Rattus norvegicus

42 known processes

Prss8

protease, serine, 8

Prss8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inorganic ion transmembrane transport GO:0098660 229 0.302
cation transmembrane transport GO:0098655 263 0.209
reproductive process GO:0022414 372 0.149
positive regulation of cell migration GO:0030335 96 0.147
regulation of cell differentiation GO:0045595 320 0.145
response to acid chemical GO:0001101 222 0.136
response to nutrient GO:0007584 248 0.131
cation transport GO:0006812 382 0.130
positive regulation of cell motility GO:2000147 97 0.125
cellular component assembly GO:0022607 360 0.119
tissue development GO:0009888 252 0.112
Mouse
regulation of nervous system development GO:0051960 264 0.102
negative regulation of multicellular organismal process GO:0051241 203 0.101
regulation of phosphorus metabolic process GO:0051174 349 0.098
response to peptide GO:1901652 292 0.098
positive regulation of nervous system development GO:0051962 178 0.095
rna biosynthetic process GO:0032774 380 0.095
positive regulation of developmental process GO:0051094 283 0.091
regulation of cell development GO:0060284 263 0.090
response to corticosteroid GO:0031960 235 0.089
male mating behavior GO:0060179 3 0.087
localization of cell GO:0051674 202 0.085
cellular response to endogenous stimulus GO:0071495 377 0.084
behavior GO:0007610 205 0.084
cellular response to stress GO:0033554 269 0.081
cell migration GO:0016477 197 0.080
regulation of molecular function GO:0065009 398 0.080
regulation of multicellular organismal development GO:2000026 376 0.079
negative regulation of rna metabolic process GO:0051253 123 0.077
regulation of cell migration GO:0030334 128 0.077
cell projection organization GO:0030030 302 0.077
cell morphogenesis GO:0000902 142 0.074
single organism reproductive process GO:0044702 297 0.072
regulation of cell proliferation GO:0042127 359 0.072
apoptotic process GO:0006915 381 0.070
brain development GO:0007420 247 0.070
transcription from rna polymerase ii promoter GO:0006366 252 0.068
regulation of cell motility GO:2000145 131 0.067
programmed cell death GO:0012501 392 0.065
gland development GO:0048732 155 0.064
inorganic cation transmembrane transport GO:0098662 202 0.064
metal ion transport GO:0030001 289 0.062
reproduction GO:0000003 245 0.061
protein complex biogenesis GO:0070271 263 0.060
central nervous system development GO:0007417 311 0.060
regulation of locomotion GO:0040012 148 0.059
rhythmic process GO:0048511 156 0.059
regulation of neurogenesis GO:0050767 247 0.059
response to peptide hormone GO:0043434 278 0.059
protein homooligomerization GO:0051260 91 0.058
cellular component biogenesis GO:0044085 368 0.058
neuron differentiation GO:0030182 368 0.058
cellular component morphogenesis GO:0032989 155 0.055
cell type specific apoptotic process GO:0097285 134 0.055
neuron development GO:0048666 286 0.055
anion transport GO:0006820 178 0.054
multicellular organismal signaling GO:0035637 44 0.053
regulation of cellular protein metabolic process GO:0032268 267 0.052
negative regulation of transcription dna templated GO:0045892 116 0.051
response to alkaloid GO:0043279 132 0.050
chemical homeostasis GO:0048878 292 0.050
neuronal action potential GO:0019228 35 0.050
negative regulation of gene expression GO:0010629 199 0.050
regulation of rna biosynthetic process GO:2001141 381 0.049
cell projection morphogenesis GO:0048858 123 0.048
positive regulation of molecular function GO:0044093 230 0.047
ion transmembrane transport GO:0034220 365 0.047
cellular response to oxygen containing compound GO:1901701 386 0.047
multicellular organism reproduction GO:0032504 233 0.046
regulation of cellular component movement GO:0051270 150 0.046
negative regulation of metabolic process GO:0009892 331 0.046
response to monosaccharide GO:0034284 159 0.045
negative regulation of cell differentiation GO:0045596 99 0.045
multi organism reproductive process GO:0044703 262 0.045
positive regulation of cellular component movement GO:0051272 102 0.045
regulation of cell projection organization GO:0031344 175 0.044
positive regulation of neurogenesis GO:0050769 165 0.044
transmembrane transport GO:0055085 412 0.044
nucleic acid templated transcription GO:0097659 379 0.043
response to external biotic stimulus GO:0043207 221 0.043
epithelium development GO:0060429 96 0.043
Mouse
regulation of catalytic activity GO:0050790 304 0.043
organic acid metabolic process GO:0006082 292 0.042
t cell activation GO:0042110 29 0.042
organ morphogenesis GO:0009887 75 0.041
divalent metal ion transport GO:0070838 132 0.041
cellular response to acid chemical GO:0071229 75 0.041
regulation of programmed cell death GO:0043067 341 0.041
positive regulation of cell development GO:0010720 176 0.041
neurological system process GO:0050877 219 0.041
protein oligomerization GO:0051259 191 0.040
multicellular organismal reproductive process GO:0048609 233 0.039
regulation of apoptotic process GO:0042981 335 0.039
multicellular organismal water homeostasis GO:0050891 4 0.039
catabolic process GO:0009056 351 0.038
positive regulation of cell proliferation GO:0008284 249 0.038
response to nutrient levels GO:0031667 370 0.038
positive regulation of locomotion GO:0040017 102 0.038
regulation of cellular component biogenesis GO:0044087 86 0.038
response to glucocorticoid GO:0051384 223 0.038
response to extracellular stimulus GO:0009991 380 0.037
muscle structure development GO:0061061 87 0.037
positive regulation of cell differentiation GO:0045597 217 0.037
head development GO:0060322 247 0.037
action potential GO:0001508 54 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.037
intracellular signal transduction GO:0035556 314 0.036
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
anion transmembrane transport GO:0098656 77 0.036
circulatory system process GO:0003013 183 0.036
cellular amino acid metabolic process GO:0006520 107 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
positive regulation of signal transduction GO:0009967 175 0.034
epithelial cell differentiation GO:0030855 71 0.034
response to oxygen levels GO:0070482 265 0.034
negative regulation of programmed cell death GO:0043069 183 0.034
response to hexose GO:0009746 144 0.034
single organism biosynthetic process GO:0044711 342 0.034
cell motility GO:0048870 202 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
muscle tissue development GO:0060537 58 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
axis specification GO:0009798 4 0.033
response to purine containing compound GO:0014074 126 0.033
calcium ion transport GO:0006816 131 0.033
protein complex assembly GO:0006461 263 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
cellular chemical homeostasis GO:0055082 247 0.032
multi multicellular organism process GO:0044706 138 0.032
response to estrogen GO:0043627 232 0.031
rna metabolic process GO:0016070 406 0.031
epiboly involved in wound healing GO:0090505 2 0.031
positive regulation of transport GO:0051050 245 0.031
Mouse
negative regulation of cell death GO:0060548 229 0.031
response to biotic stimulus GO:0009607 226 0.031
chemotaxis GO:0006935 66 0.030
neuron projection development GO:0031175 273 0.030
response to inorganic substance GO:0010035 377 0.030
response to retinoic acid GO:0032526 63 0.030
heart morphogenesis GO:0003007 3 0.029
biological adhesion GO:0022610 110 0.029
regulation of protein phosphorylation GO:0001932 183 0.029
response to metal ion GO:0010038 253 0.029
regulation of cell morphogenesis GO:0022604 77 0.029
epiboly GO:0090504 2 0.029
homeostatic process GO:0042592 331 0.028
regeneration GO:0031099 163 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
positive regulation of gene expression GO:0010628 244 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
immune system process GO:0002376 204 0.027
cellular response to external stimulus GO:0071496 118 0.027
macromolecular complex assembly GO:0065003 273 0.027
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
hepaticobiliary system development GO:0061008 90 0.027
regulation of cellular component organization GO:0051128 368 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.026
response to molecule of bacterial origin GO:0002237 194 0.026
positive regulation of protein metabolic process GO:0051247 178 0.026
positive regulation of apoptotic process GO:0043065 154 0.026
regulation of response to wounding GO:1903034 69 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
regulation of immune response GO:0050776 55 0.025
response to decreased oxygen levels GO:0036293 237 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.025
regulation of neuron projection development GO:0010975 161 0.025
cellular response to lipid GO:0071396 201 0.025
regulation of kinase activity GO:0043549 117 0.025
wound healing spreading of epidermal cells GO:0035313 2 0.025
negative regulation of cell development GO:0010721 82 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
embryonic pattern specification GO:0009880 1 0.024
wound healing GO:0042060 122 0.024
regulation of phagocytosis engulfment GO:0060099 4 0.024
renal system development GO:0072001 67 0.024
regulation of neuron differentiation GO:0045664 208 0.024
negative regulation of nucleic acid templated transcription GO:1903507 117 0.024
cell adhesion GO:0007155 110 0.024
sexual reproduction GO:0019953 148 0.024
response to vitamin GO:0033273 131 0.024
neuron projection morphogenesis GO:0048812 122 0.024
cell part morphogenesis GO:0032990 123 0.023
regulation of response to external stimulus GO:0032101 106 0.023
transmission of nerve impulse GO:0019226 42 0.023
gastrulation GO:0007369 2 0.023
b cell differentiation GO:0030183 2 0.023
sensory perception GO:0007600 101 0.023
negative regulation of signal transduction GO:0009968 83 0.023
tube development GO:0035295 89 0.023
single organism behavior GO:0044708 130 0.023
response to other organism GO:0051707 220 0.022
cellular modified amino acid metabolic process GO:0006575 61 0.022
tissue morphogenesis GO:0048729 22 0.022
transcription dna templated GO:0006351 377 0.022
neuron recognition GO:0008038 9 0.022
neuron death GO:0070997 127 0.022
monovalent inorganic cation transport GO:0015672 172 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
response to transforming growth factor beta GO:0071559 46 0.022
cellular response to growth factor stimulus GO:0071363 162 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
cation homeostasis GO:0055080 195 0.022
grooming behavior GO:0007625 4 0.022
sodium ion transmembrane transport GO:0035725 67 0.022
cellular amine metabolic process GO:0044106 38 0.021
reactive oxygen species metabolic process GO:0072593 37 0.021
regulation of membrane potential GO:0042391 110 0.021
b cell activation involved in immune response GO:0002312 1 0.021
regulation of growth GO:0040008 105 0.021
secretion GO:0046903 307 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.021
cellular homeostasis GO:0019725 252 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
regulation of stem cell differentiation GO:2000736 2 0.020
urogenital system development GO:0001655 78 0.020
negative regulation of nervous system development GO:0051961 79 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
regulation of signal transduction GO:0009966 318 0.020
regulation of rna metabolic process GO:0051252 391 0.020
protein localization GO:0008104 191 0.019
regulation of secretion by cell GO:1903530 208 0.019
gamete generation GO:0007276 124 0.019
protein complex subunit organization GO:0071822 302 0.019
response to molecule of fungal origin GO:0002238 3 0.019
oxoacid metabolic process GO:0043436 290 0.019
regulation of system process GO:0044057 208 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
regulation of neuron death GO:1901214 115 0.019
regulation of protein metabolic process GO:0051246 289 0.019
dephosphorylation GO:0016311 98 0.019
response to ketone GO:1901654 182 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
cellular component movement GO:0006928 248 0.018
negative regulation of molecular function GO:0044092 133 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
ras protein signal transduction GO:0007265 29 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
synapse organization GO:0050808 46 0.018
macromolecule localization GO:0033036 252 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
chemosensory behavior GO:0007635 2 0.018
regulation of ion transport GO:0043269 245 0.018
Mouse
protein transport GO:0015031 132 0.018
response to carbohydrate GO:0009743 183 0.018
olfactory behavior GO:0042048 2 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
ensheathment of neurons GO:0007272 40 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
lymphocyte activation involved in immune response GO:0002285 3 0.017
epithelial cell proliferation GO:0050673 54 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
response to oxidative stress GO:0006979 186 0.017
mesoderm development GO:0007498 2 0.017
negative regulation of cell communication GO:0010648 158 0.017
salivary gland morphogenesis GO:0007435 1 0.017
inflammatory response GO:0006954 150 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
hepatocyte differentiation GO:0070365 8 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
single organism organelle organization GO:1902589 180 0.016
response to growth factor GO:0070848 189 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
response to wounding GO:0009611 254 0.016
positive regulation of cell death GO:0010942 184 0.016
response to hypoxia GO:0001666 231 0.016
regulation of body fluid levels GO:0050878 90 0.016
bmp signaling pathway GO:0030509 4 0.016
hormone metabolic process GO:0042445 69 0.016
regulation of transcription dna templated GO:0006355 374 0.016
organic acid transport GO:0015849 116 0.016
nitrogen compound transport GO:0071705 229 0.016
salivary gland development GO:0007431 3 0.016
lung development GO:0030324 43 0.016
sodium ion transport GO:0006814 82 0.016
aging GO:0007568 241 0.016
myeloid leukocyte activation GO:0002274 36 0.015
negative regulation of neuron death GO:1901215 69 0.015
cell activation GO:0001775 97 0.015
synapse assembly GO:0007416 29 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
carbohydrate homeostasis GO:0033500 75 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
lens fiber cell differentiation GO:0070306 3 0.015
male sex differentiation GO:0046661 64 0.015
mesoderm morphogenesis GO:0048332 1 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
cellular ketone metabolic process GO:0042180 51 0.015
multicellular organismal response to stress GO:0033555 25 0.015
negative regulation of signaling GO:0023057 157 0.015
positive regulation of signaling GO:0023056 270 0.015
cardiovascular system development GO:0072358 134 0.015
neural crest cell development GO:0014032 2 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
inorganic anion transport GO:0015698 41 0.015
regulation of transferase activity GO:0051338 123 0.015
regulation of phosphorylation GO:0042325 248 0.015
wound healing spreading of cells GO:0044319 2 0.014
taxis GO:0042330 67 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
divalent inorganic cation transport GO:0072511 134 0.014
positive regulation of catecholamine secretion GO:0033605 13 0.014
positive regulation of ion transport GO:0043270 94 0.014
Mouse
regulation of inflammatory response GO:0050727 48 0.014
regulation of response to stress GO:0080134 126 0.014
cellular catabolic process GO:0044248 295 0.014
respiratory tube development GO:0030323 43 0.014
positive regulation of defense response GO:0031349 37 0.014
lymphoid progenitor cell differentiation GO:0002320 2 0.014
response to activity GO:0014823 73 0.014
axon ensheathment GO:0008366 40 0.014
response to glucose GO:0009749 136 0.014
response to ethanol GO:0045471 162 0.013
regulation of cell adhesion GO:0030155 52 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
leukocyte activation GO:0045321 76 0.013
cellular response to molecule of bacterial origin GO:0071219 56 0.013
leukocyte migration GO:0050900 38 0.013
regulation of synapse structure and activity GO:0050803 21 0.013
neuron apoptotic process GO:0051402 88 0.013
respiratory system development GO:0060541 45 0.013
lipid metabolic process GO:0006629 283 0.013
negative regulation of transport GO:0051051 136 0.013
organic anion transport GO:0015711 132 0.013
ion homeostasis GO:0050801 212 0.013
cellular response to oxidative stress GO:0034599 76 0.013
exocytosis GO:0006887 60 0.013
cell recognition GO:0008037 11 0.013
protein maturation GO:0051604 68 0.013
actin filament depolymerization GO:0030042 3 0.013
immunoglobulin mediated immune response GO:0016064 4 0.013
lipid biosynthetic process GO:0008610 128 0.013
axon development GO:0061564 96 0.013
cellular metal ion homeostasis GO:0006875 172 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
mammary gland epithelium development GO:0061180 1 0.012
macromolecule catabolic process GO:0009057 58 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
membrane organization GO:0061024 94 0.012
regulation of protein kinase activity GO:0045859 105 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
regulation of protein modification process GO:0031399 194 0.012
spindle organization GO:0007051 2 0.012
carboxylic acid transport GO:0046942 115 0.012
mammary gland development GO:0030879 38 0.012
response to progesterone GO:0032570 48 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
circadian rhythm GO:0007623 88 0.012
sequestering of calcium ion GO:0051208 8 0.012
response to cytokine GO:0034097 215 0.012
regulation of synaptic transmission GO:0050804 141 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
regulation of defense response GO:0031347 68 0.012
myelination GO:0042552 39 0.011
vesicle mediated transport GO:0016192 181 0.011
cholesterol homeostasis GO:0042632 3 0.011
locomotion GO:0040011 237 0.011
learning or memory GO:0007611 90 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
cellular response to retinoic acid GO:0071300 27 0.011
potassium ion transmembrane transport GO:0071805 71 0.011
regulation of notch signaling pathway GO:0008593 3 0.011
organic substance catabolic process GO:1901575 316 0.011
regulation of secretion GO:0051046 224 0.011
spermatogenesis GO:0007283 99 0.011
organelle organization GO:0006996 266 0.011
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
mapk cascade GO:0000165 140 0.011
reproductive system development GO:0061458 128 0.011
regulation of embryonic development GO:0045995 2 0.011
chromosome segregation GO:0007059 2 0.011
behavioral response to nicotine GO:0035095 2 0.011
positive regulation of growth GO:0045927 55 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
gliogenesis GO:0042063 93 0.011
cellular response to nutrient levels GO:0031669 60 0.011
regulation of cytokine production GO:0001817 56 0.011
cell cell signaling GO:0007267 335 0.011
response to lipopolysaccharide GO:0032496 191 0.011
positive regulation of protein modification process GO:0031401 142 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
cellular potassium ion transport GO:0071804 72 0.010
meiotic cell cycle process GO:1903046 3 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
response to bacterium GO:0009617 200 0.010
glucose homeostasis GO:0042593 75 0.010
mononuclear cell proliferation GO:0032943 29 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010
protein processing GO:0016485 68 0.010
morphogenesis of an epithelium GO:0002009 20 0.010
sensory organ development GO:0007423 74 0.010
positive regulation of phagocytosis engulfment GO:0060100 4 0.010
pseudopodium organization GO:0031268 3 0.010

Prss8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
respiratory system disease DOID:1579 0 0.141
disease of anatomical entity DOID:7 0 0.141
lower respiratory tract disease DOID:0050161 0 0.141
kidney disease DOID:557 0 0.026
urinary system disease DOID:18 0 0.026
renal tubular transport disease DOID:447 0 0.017
nervous system disease DOID:863 0 0.015
eye and adnexa disease DOID:1492 0 0.015
sensory system disease DOID:0050155 0 0.015
integumentary system disease DOID:16 0 0.013
disease of metabolism DOID:0014667 0 0.012