Rattus norvegicus

8 known processes

Psmb2

proteasome (prosome, macropain) subunit, beta type 2

Psmb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 14 0.808
Yeast
proteasomal protein catabolic process GO:0010498 8 0.475
Yeast
macromolecule catabolic process GO:0009057 58 0.399
Yeast
protein catabolic process GO:0030163 30 0.365
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.334
Yeast
cellular protein catabolic process GO:0044257 19 0.330
Yeast
modification dependent protein catabolic process GO:0019941 14 0.311
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.272
Yeast
cellular response to stress GO:0033554 269 0.242
Fly
proteolysis GO:0006508 175 0.221
Yeast
ubiquitin dependent protein catabolic process GO:0006511 14 0.171
Yeast
cation transport GO:0006812 382 0.150
pigment metabolic process GO:0042440 7 0.144
locomotion GO:0040011 237 0.125
positive regulation of molecular function GO:0044093 230 0.109
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.105
regulation of rna metabolic process GO:0051252 391 0.104
regulation of nucleic acid templated transcription GO:1903506 380 0.099
aging GO:0007568 241 0.096
Worm
regulation of transcription dna templated GO:0006355 374 0.089
regulation of rna biosynthetic process GO:2001141 381 0.085
cellular macromolecule catabolic process GO:0044265 29 0.084
Yeast
immune response GO:0006955 104 0.080
response to inorganic substance GO:0010035 377 0.073
cellular amino acid metabolic process GO:0006520 107 0.071
rna metabolic process GO:0016070 406 0.068
oxidation reduction process GO:0055114 304 0.065
cellular response to dna damage stimulus GO:0006974 19 0.064
Fly
positive regulation of intracellular signal transduction GO:1902533 138 0.064
transcription dna templated GO:0006351 377 0.063
regulation of cellular amine metabolic process GO:0033238 8 0.061
nucleic acid templated transcription GO:0097659 379 0.059
regulation of immune system process GO:0002682 123 0.058
cellular catabolic process GO:0044248 295 0.058
Yeast
catabolic process GO:0009056 351 0.054
Yeast
immune system process GO:0002376 204 0.054
apoptotic process GO:0006915 381 0.054
positive regulation of nucleic acid templated transcription GO:1903508 197 0.054
positive regulation of biosynthetic process GO:0009891 319 0.047
positive regulation of gene expression GO:0010628 244 0.046
regulation of molecular function GO:0065009 398 0.046
Yeast
positive regulation of transport GO:0051050 245 0.045
transcription from rna polymerase ii promoter GO:0006366 252 0.045
response to acid chemical GO:0001101 222 0.044
intracellular transport GO:0046907 185 0.044
macromolecule localization GO:0033036 252 0.044
response to external biotic stimulus GO:0043207 221 0.044
rna biosynthetic process GO:0032774 380 0.044
regulation of ion transport GO:0043269 245 0.043
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.041
regulation of cellular amino acid metabolic process GO:0006521 2 0.041
macromolecular complex subunit organization GO:0043933 339 0.040
synaptic growth at neuromuscular junction GO:0051124 1 0.039
protein localization to organelle GO:0033365 57 0.039
cellular amine metabolic process GO:0044106 38 0.038
positive regulation of transcription dna templated GO:0045893 197 0.038
neuron differentiation GO:0030182 368 0.038
positive regulation of ion transport GO:0043270 94 0.038
calcium ion homeostasis GO:0055074 162 0.038
defense response GO:0006952 194 0.037
ion homeostasis GO:0050801 212 0.037
metal ion transport GO:0030001 289 0.037
cellular ketone metabolic process GO:0042180 51 0.036
amine metabolic process GO:0009308 38 0.035
reproduction GO:0000003 245 0.035
Worm Fly
cellular response to reactive oxygen species GO:0034614 55 0.034
synaptic transmission GO:0007268 235 0.034
response to wounding GO:0009611 254 0.033
homeostatic process GO:0042592 331 0.033
organic hydroxy compound metabolic process GO:1901615 115 0.032
cellular calcium ion homeostasis GO:0006874 160 0.032
cellular cation homeostasis GO:0030003 180 0.032
organ morphogenesis GO:0009887 75 0.031
response to hydrogen peroxide GO:0042542 89 0.031
regulation of metal ion transport GO:0010959 118 0.031
regulation of cell proliferation GO:0042127 359 0.030
response to ketone GO:1901654 182 0.030
cation transmembrane transport GO:0098655 263 0.029
muscle structure development GO:0061061 87 0.029
reactive oxygen species metabolic process GO:0072593 37 0.029
negative regulation of innate immune response GO:0045824 4 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.028
positive regulation of developmental process GO:0051094 283 0.028
regulation of cellular component biogenesis GO:0044087 86 0.028
response to biotic stimulus GO:0009607 226 0.028
metal ion homeostasis GO:0055065 186 0.028
sequestering of calcium ion GO:0051208 8 0.027
negative regulation of response to stimulus GO:0048585 155 0.027
single organism intracellular transport GO:1902582 166 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
transmembrane transport GO:0055085 412 0.026
cellular ion homeostasis GO:0006873 184 0.026
tube development GO:0035295 89 0.026
multi organism reproductive process GO:0044703 262 0.026
peptidyl amino acid modification GO:0018193 126 0.025
embryonic pattern specification GO:0009880 1 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.025
mitotic spindle organization GO:0007052 2 0.024
programmed cell death GO:0012501 392 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
Yeast
positive regulation of rna metabolic process GO:0051254 203 0.024
protein localization to nucleus GO:0034504 39 0.024
cell cycle checkpoint GO:0000075 2 0.024
maintenance of location GO:0051235 17 0.024
regulation of lipid metabolic process GO:0019216 68 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
inorganic ion transmembrane transport GO:0098660 229 0.023
response to oxidative stress GO:0006979 186 0.023
gastrulation GO:0007369 2 0.022
regulation of cell cycle GO:0051726 73 0.022
negative regulation of metabolic process GO:0009892 331 0.022
cellular protein localization GO:0034613 122 0.022
monosaccharide metabolic process GO:0005996 61 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
multicellular organism reproduction GO:0032504 233 0.022
Fly
organic substance catabolic process GO:1901575 316 0.021
Yeast
positive regulation of cellular component biogenesis GO:0044089 55 0.021
cellular chemical homeostasis GO:0055082 247 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
negative regulation of signaling GO:0023057 157 0.021
divalent metal ion transport GO:0070838 132 0.021
adult locomotory behavior GO:0008344 4 0.021
inorganic cation transmembrane transport GO:0098662 202 0.021
response to molecule of bacterial origin GO:0002237 194 0.021
sequestering of metal ion GO:0051238 9 0.021
regulation of response to stress GO:0080134 126 0.020
cation homeostasis GO:0055080 195 0.020
regulation of signal transduction GO:0009966 318 0.019
protein complex subunit organization GO:0071822 302 0.019
central nervous system development GO:0007417 311 0.019
response to corticosteroid GO:0031960 235 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
embryo development GO:0009790 49 0.019
Worm
cellular component assembly GO:0022607 360 0.019
response to decreased oxygen levels GO:0036293 237 0.019
negative regulation of cell death GO:0060548 229 0.018
regulation of immune response GO:0050776 55 0.018
nucleocytoplasmic transport GO:0006913 48 0.018
protein import GO:0017038 37 0.018
ion transmembrane transport GO:0034220 365 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
response to other organism GO:0051707 220 0.018
inflammatory response GO:0006954 150 0.018
positive regulation of cell communication GO:0010647 271 0.017
spermatogenesis GO:0007283 99 0.017
positive regulation of signal transduction GO:0009967 175 0.017
organelle organization GO:0006996 266 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
molting cycle GO:0042303 3 0.017
cell migration GO:0016477 197 0.017
cellular response to oxidative stress GO:0034599 76 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
neurotransmitter uptake GO:0001504 3 0.016
spindle organization GO:0007051 2 0.016
cellular component movement GO:0006928 248 0.016
regulation of ion homeostasis GO:2000021 63 0.016
single organism reproductive process GO:0044702 297 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
cytoplasmic transport GO:0016482 115 0.016
neuron projection development GO:0031175 273 0.016
response to extracellular stimulus GO:0009991 380 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
response to reactive oxygen species GO:0000302 120 0.016
negative regulation of gene expression GO:0010629 199 0.015
oxoacid metabolic process GO:0043436 290 0.015
positive regulation of jnk cascade GO:0046330 13 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
carboxylic acid metabolic process GO:0019752 289 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
calcium ion transmembrane transport GO:0070588 70 0.015
response to monosaccharide GO:0034284 159 0.015
tetrapyrrole metabolic process GO:0033013 11 0.015
regulation of transmembrane transporter activity GO:0022898 49 0.015
regulation of protein kinase activity GO:0045859 105 0.015
regulation of sequestering of calcium ion GO:0051282 26 0.015
regulation of phosphorylation GO:0042325 248 0.015
regulation of cellular localization GO:0060341 263 0.015
cellular response to external stimulus GO:0071496 118 0.015
eye morphogenesis GO:0048592 4 0.015
extracellular matrix constituent secretion GO:0070278 4 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
single organism behavior GO:0044708 130 0.015
response to nutrient GO:0007584 248 0.014
negative regulation of defense response GO:0031348 19 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
muscle tissue development GO:0060537 58 0.014
chromosome segregation GO:0007059 2 0.014
regulation of protein complex assembly GO:0043254 33 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
cellular homeostasis GO:0019725 252 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of lipid kinase activity GO:0090218 2 0.014
small molecule biosynthetic process GO:0044283 124 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
response to nutrient levels GO:0031667 370 0.013
male gamete generation GO:0048232 99 0.013
regulation of cell growth GO:0001558 85 0.013
macromolecular complex assembly GO:0065003 273 0.013
regulation of growth GO:0040008 105 0.013
calcium ion transport into cytosol GO:0060402 38 0.013
regulation of cell cycle process GO:0010564 31 0.013
retina morphogenesis in camera type eye GO:0060042 1 0.013
tissue development GO:0009888 252 0.013
regulation of programmed cell death GO:0043067 341 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
response to lipopolysaccharide GO:0032496 191 0.012
growth GO:0040007 165 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
chemical homeostasis GO:0048878 292 0.012
cell projection organization GO:0030030 302 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
response to oxygen levels GO:0070482 265 0.012
protein localization GO:0008104 191 0.012
response to metal ion GO:0010038 253 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
negative regulation of cell communication GO:0010648 158 0.012
response to glucocorticoid GO:0051384 223 0.012
muscle organ development GO:0007517 50 0.012
regulation of cell differentiation GO:0045595 320 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
cellular response to nutrient levels GO:0031669 60 0.012
divalent inorganic cation transport GO:0072511 134 0.012
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
regulation of response to wounding GO:1903034 69 0.012
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
mitotic cell cycle process GO:1903047 35 0.012
negative regulation of response to external stimulus GO:0032102 37 0.012
protein import into nucleus GO:0006606 35 0.012
liver development GO:0001889 90 0.012
innate immune response GO:0045087 35 0.011
regulation of transmembrane transport GO:0034762 122 0.011
regulation of defense response GO:0031347 68 0.011
nucleoside transport GO:0015858 8 0.011
response to peptide hormone GO:0043434 278 0.011
cytosolic calcium ion transport GO:0060401 39 0.011
response to hyperoxia GO:0055093 45 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
single organism cellular localization GO:1902580 102 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
organic acid metabolic process GO:0006082 292 0.011
intracellular signal transduction GO:0035556 314 0.011
positive regulation of calcium ion transport GO:0051928 36 0.011
regulation of cell motility GO:2000145 131 0.011
brain development GO:0007420 247 0.011
circulatory system process GO:0003013 183 0.011
sexual reproduction GO:0019953 148 0.011
single organism catabolic process GO:0044712 283 0.011
mitotic cell cycle GO:0000278 49 0.010
behavior GO:0007610 205 0.010
axis specification GO:0009798 4 0.010
response to carbohydrate GO:0009743 183 0.010
pseudopodium organization GO:0031268 3 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
regulation of homeostatic process GO:0032844 101 0.010
response to purine containing compound GO:0014074 126 0.010

Psmb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
musculoskeletal system disease DOID:17 0 0.022
central nervous system disease DOID:331 0 0.020
nervous system disease DOID:863 0 0.020
brain disease DOID:936 0 0.011