Rattus norvegicus

0 known processes

Psmc1

proteasome (prosome, macropain) 26S subunit, ATPase, 1

(Aliases: s4)

Psmc1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 3 0.997
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 3 0.988
transcription initiation from rna polymerase ii promoter GO:0006367 3 0.983
atp catabolic process GO:0006200 54 0.976
dna templated transcription initiation GO:0006352 4 0.975
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 3 0.964
purine nucleoside monophosphate catabolic process GO:0009128 55 0.921
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.914
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.897
nucleoside monophosphate catabolic process GO:0009125 56 0.872
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.817
dna templated transcriptional preinitiation complex assembly GO:0070897 3 0.789
modification dependent macromolecule catabolic process GO:0043632 14 0.731
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.710
ribonucleoside triphosphate catabolic process GO:0009203 122 0.666
cellular response to stress GO:0033554 269 0.660
Fly
catabolic process GO:0009056 351 0.580
Worm
ribonucleotide catabolic process GO:0009261 136 0.572
purine nucleoside triphosphate catabolic process GO:0009146 122 0.565
organic substance catabolic process GO:1901575 316 0.561
Worm
cellular protein catabolic process GO:0044257 19 0.549
purine nucleotide catabolic process GO:0006195 136 0.522
organonitrogen compound catabolic process GO:1901565 179 0.517
cellular catabolic process GO:0044248 295 0.516
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.515
organophosphate catabolic process GO:0046434 148 0.501
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.489
ubiquitin dependent protein catabolic process GO:0006511 14 0.487
positive regulation of dna templated transcription initiation GO:2000144 3 0.464
regulation of molecular function GO:0065009 398 0.460
regulation of cellular component organization GO:0051128 368 0.446
regulation of rna metabolic process GO:0051252 391 0.443
glycosyl compound catabolic process GO:1901658 126 0.440
purine nucleoside catabolic process GO:0006152 124 0.434
ribonucleoside monophosphate catabolic process GO:0009158 55 0.420
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.418
rna biosynthetic process GO:0032774 380 0.405
proteolysis GO:0006508 175 0.403
Fly
transcription from rna polymerase ii promoter GO:0006366 252 0.402
aromatic compound catabolic process GO:0019439 168 0.391
regulation of transcription dna templated GO:0006355 374 0.387
positive regulation of gene expression GO:0010628 244 0.385
macromolecule catabolic process GO:0009057 58 0.380
Worm
carbohydrate derivative catabolic process GO:1901136 147 0.375
positive regulation of rna biosynthetic process GO:1902680 197 0.373
purine ribonucleoside catabolic process GO:0046130 124 0.366
protein complex biogenesis GO:0070271 263 0.364
Fly
regulation of rna biosynthetic process GO:2001141 381 0.363
regulation of nucleic acid templated transcription GO:1903506 380 0.361
purine nucleoside monophosphate metabolic process GO:0009126 84 0.357
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.353
positive regulation of biosynthetic process GO:0009891 319 0.347
atp metabolic process GO:0046034 72 0.344
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.343
transcription dna templated GO:0006351 377 0.342
cellular macromolecule catabolic process GO:0044265 29 0.337
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.337
purine ribonucleotide catabolic process GO:0009154 136 0.327
ribonucleoside catabolic process GO:0042454 126 0.325
rna metabolic process GO:0016070 406 0.318
nucleoside phosphate metabolic process GO:0006753 283 0.318
modification dependent protein catabolic process GO:0019941 14 0.308
positive regulation of transcription dna templated GO:0045893 197 0.300
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.287
nucleoside phosphate catabolic process GO:1901292 140 0.285
single organism catabolic process GO:0044712 283 0.283
positive regulation of rna metabolic process GO:0051254 203 0.282
ribonucleoside triphosphate metabolic process GO:0009199 141 0.271
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.266
purine containing compound catabolic process GO:0072523 138 0.266
nucleotide metabolic process GO:0009117 279 0.265
nucleoside triphosphate catabolic process GO:0009143 123 0.258
nucleoside monophosphate metabolic process GO:0009123 93 0.254
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.253
organophosphate metabolic process GO:0019637 370 0.253
organelle organization GO:0006996 266 0.238
Fly
nucleobase containing compound catabolic process GO:0034655 152 0.236
cellular response to dna damage stimulus GO:0006974 19 0.231
Fly
positive regulation of cellular component biogenesis GO:0044089 55 0.229
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 3 0.224
embryo development GO:0009790 49 0.224
Worm
regulation of cellular protein metabolic process GO:0032268 267 0.223
nucleic acid templated transcription GO:0097659 379 0.222
purine nucleotide metabolic process GO:0006163 229 0.218
positive regulation of cellular component organization GO:0051130 200 0.217
positive regulation of cellular biosynthetic process GO:0031328 295 0.216
cellular macromolecule localization GO:0070727 122 0.212
positive regulation of nucleic acid templated transcription GO:1903508 197 0.212
protein catabolic process GO:0030163 30 0.212
Worm
cellular protein localization GO:0034613 122 0.207
nucleoside triphosphate metabolic process GO:0009141 144 0.207
nucleoside catabolic process GO:0009164 126 0.201
nucleotide catabolic process GO:0009166 139 0.199
reproductive process GO:0022414 372 0.197
regulation of cellular component biogenesis GO:0044087 86 0.197
single organism reproductive process GO:0044702 297 0.189
gonad development GO:0008406 104 0.185
reproductive system development GO:0061458 128 0.182
carbohydrate derivative metabolic process GO:1901135 346 0.182
macromolecular complex subunit organization GO:0043933 339 0.180
Fly
ribonucleoside monophosphate metabolic process GO:0009161 88 0.177
single organism membrane organization GO:0044802 74 0.168
protein targeting GO:0006605 61 0.167
proteasomal protein catabolic process GO:0010498 8 0.167
reproduction GO:0000003 245 0.163
Worm
heterocycle catabolic process GO:0046700 167 0.159
nucleobase containing small molecule metabolic process GO:0055086 316 0.155
regulation of protein complex assembly GO:0043254 33 0.151
protein localization to organelle GO:0033365 57 0.147
single organism cellular localization GO:1902580 102 0.144
positive regulation of catalytic activity GO:0043085 184 0.141
protein complex assembly GO:0006461 263 0.141
Fly
development of primary sexual characteristics GO:0045137 107 0.138
vesicle mediated transport GO:0016192 181 0.131
organic cyclic compound catabolic process GO:1901361 175 0.128
protein dna complex subunit organization GO:0071824 7 0.127
purine ribonucleotide metabolic process GO:0009150 227 0.126
negative regulation of gene expression GO:0010629 199 0.126
purine containing compound metabolic process GO:0072521 253 0.125
cellular protein complex assembly GO:0043623 44 0.124
regulation of phosphate metabolic process GO:0019220 349 0.122
purine ribonucleoside metabolic process GO:0046128 168 0.121
membrane organization GO:0061024 94 0.121
anatomical structure morphogenesis GO:0009653 298 0.120
establishment of protein localization to organelle GO:0072594 44 0.115
reproductive structure development GO:0048608 128 0.114
macromolecule localization GO:0033036 252 0.109
Worm
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.109
ribonucleotide metabolic process GO:0009259 231 0.109
purine nucleoside metabolic process GO:0042278 169 0.108
regulation of catabolic process GO:0009894 113 0.107
macromolecular complex assembly GO:0065003 273 0.106
Fly
purine nucleoside triphosphate metabolic process GO:0009144 141 0.106
cellular nitrogen compound catabolic process GO:0044270 163 0.104
developmental process involved in reproduction GO:0003006 159 0.104
ribose phosphate metabolic process GO:0019693 235 0.103
regulation of growth GO:0040008 105 0.095
apoptotic process GO:0006915 381 0.094
sex differentiation GO:0007548 113 0.093
eye morphogenesis GO:0048592 4 0.090
regulation of dna templated transcription initiation GO:2000142 3 0.089
cellular component assembly GO:0022607 360 0.089
Fly
negative regulation of biosynthetic process GO:0009890 168 0.088
sexual reproduction GO:0019953 148 0.088
regulation of cell proliferation GO:0042127 359 0.087
mitotic spindle organization GO:0007052 2 0.083
Fly
binding of sperm to zona pellucida GO:0007339 1 0.081
multicellular organismal reproductive process GO:0048609 233 0.080
divalent metal ion transport GO:0070838 132 0.079
regulation of cell differentiation GO:0045595 320 0.079
regulation of cell development GO:0060284 263 0.076
hepaticobiliary system development GO:0061008 90 0.076
positive regulation of molecular function GO:0044093 230 0.075
negative regulation of macromolecule metabolic process GO:0010605 260 0.075
negative regulation of cellular metabolic process GO:0031324 281 0.075
multicellular organism reproduction GO:0032504 233 0.074
ribonucleoside metabolic process GO:0009119 174 0.073
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.069
protein import GO:0017038 37 0.069
programmed cell death GO:0012501 392 0.067
glycosyl compound metabolic process GO:1901657 182 0.065
cell cycle GO:0007049 101 0.065
Fly
establishment of protein localization GO:0045184 141 0.064
Worm
regulation of protein metabolic process GO:0051246 289 0.064
regulation of phosphorus metabolic process GO:0051174 349 0.062
nucleoside metabolic process GO:0009116 179 0.061
protein complex subunit organization GO:0071822 302 0.061
Fly
cellular macromolecular complex assembly GO:0034622 58 0.061
positive regulation of hydrolase activity GO:0051345 86 0.060
multi organism reproductive process GO:0044703 262 0.056
post embryonic development GO:0009791 6 0.055
negative regulation of metabolic process GO:0009892 331 0.055
negative regulation of protein transport GO:0051224 17 0.055
intracellular protein transport GO:0006886 79 0.054
regulation of catalytic activity GO:0050790 304 0.054
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.053
response to peptide hormone GO:0043434 278 0.053
negative regulation of multicellular organismal process GO:0051241 203 0.049
cytoplasmic transport GO:0016482 115 0.048
negative regulation of cellular biosynthetic process GO:0031327 161 0.048
locomotion GO:0040011 237 0.048
positive regulation of phosphorus metabolic process GO:0010562 262 0.047
protein localization GO:0008104 191 0.046
Worm
regulation of retinal cell programmed cell death GO:0046668 1 0.046
negative regulation of translational initiation GO:0045947 5 0.045
negative regulation of transcription dna templated GO:0045892 116 0.044
double strand break repair GO:0006302 1 0.044
negative regulation of nucleic acid templated transcription GO:1903507 117 0.042
negative regulation of cell differentiation GO:0045596 99 0.041
spindle organization GO:0007051 2 0.041
Fly
negative regulation of molecular function GO:0044092 133 0.041
regulation of hydrolase activity GO:0051336 143 0.041
cytoskeleton organization GO:0007010 111 0.041
Fly
sperm egg recognition GO:0035036 1 0.039
mitotic cell cycle GO:0000278 49 0.037
Fly
cellular component biogenesis GO:0044085 368 0.037
Fly
enzyme linked receptor protein signaling pathway GO:0007167 116 0.037
positive regulation of catabolic process GO:0009896 78 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.036
negative regulation of rna biosynthetic process GO:1902679 118 0.035
rhythmic process GO:0048511 156 0.035
organ morphogenesis GO:0009887 75 0.034
negative regulation of transport GO:0051051 136 0.032
cell cycle process GO:0022402 57 0.032
Fly
single organism intracellular transport GO:1902582 166 0.032
single fertilization GO:0007338 3 0.030
response to virus GO:0009615 17 0.030
regulation of programmed cell death GO:0043067 341 0.029
trna metabolic process GO:0006399 4 0.029
response to peptide GO:1901652 292 0.029
cellular response to lipid GO:0071396 201 0.028
protein prenylation GO:0018342 4 0.028
positive regulation of protein metabolic process GO:0051247 178 0.028
regulation of calcium ion transport GO:0051924 77 0.028
toxin transport GO:1901998 3 0.027
response to inorganic substance GO:0010035 377 0.027
regulation of protein modification process GO:0031399 194 0.027
regulation of cellular catabolic process GO:0031329 101 0.027
membrane fusion GO:0061025 26 0.027
positive regulation of cellular catabolic process GO:0031331 71 0.026
positive regulation of protein modification process GO:0031401 142 0.026
regulation of multicellular organismal development GO:2000026 376 0.026
negative regulation of rna metabolic process GO:0051253 123 0.026
response to hexose GO:0009746 144 0.026
cell cell recognition GO:0009988 1 0.025
embryo development ending in birth or egg hatching GO:0009792 22 0.025
Worm
aging GO:0007568 241 0.025
Worm
immune system process GO:0002376 204 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.024
extracellular matrix constituent secretion GO:0070278 4 0.024
ovulation cycle GO:0042698 67 0.024
regulation of protein catabolic process GO:0042176 16 0.024
chromosome segregation GO:0007059 2 0.024
protein transport GO:0015031 132 0.023
Worm
negative regulation of cell death GO:0060548 229 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
divalent inorganic cation transport GO:0072511 134 0.022
transmembrane transport GO:0055085 412 0.022
chordate embryonic development GO:0043009 18 0.022
response to biotic stimulus GO:0009607 226 0.022
protein import into nucleus GO:0006606 35 0.022
trna aminoacylation GO:0043039 3 0.022
neuron differentiation GO:0030182 368 0.021
calcium ion transport GO:0006816 131 0.021
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
cation transport GO:0006812 382 0.021
tissue development GO:0009888 252 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.020
chromatin remodeling GO:0006338 3 0.020
organ regeneration GO:0031100 101 0.020
maintenance of location GO:0051235 17 0.020
ras protein signal transduction GO:0007265 29 0.020
negative regulation of protein metabolic process GO:0051248 114 0.019
regulation of protein localization GO:0032880 81 0.019
regulation of phosphorylation GO:0042325 248 0.019
response to carbohydrate GO:0009743 183 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
rna catabolic process GO:0006401 3 0.018
gamete generation GO:0007276 124 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
regulation of cellular localization GO:0060341 263 0.018
regulation of immune system process GO:0002682 123 0.018
endocytosis GO:0006897 84 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
oxoacid metabolic process GO:0043436 290 0.017
ncrna metabolic process GO:0034660 8 0.017
female gonad development GO:0008585 53 0.016
single organism organelle organization GO:1902589 180 0.016
Fly
regulation of cell growth GO:0001558 85 0.016
osteoblast differentiation GO:0001649 26 0.016
microtubule cytoskeleton organization GO:0000226 25 0.015
Fly
negative regulation of signaling GO:0023057 157 0.015
cell recognition GO:0008037 11 0.015
male gamete generation GO:0048232 99 0.015
gland development GO:0048732 155 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
negative regulation of autophagy GO:0010507 1 0.014
secretion GO:0046903 307 0.014
Worm
metal ion transport GO:0030001 289 0.014
intracellular signal transduction GO:0035556 314 0.014
response to calcium ion GO:0051592 59 0.014
neuron development GO:0048666 286 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
response to other organism GO:0051707 220 0.014
regulation of metal ion transport GO:0010959 118 0.014
intracellular transport GO:0046907 185 0.013
regulation of apoptotic process GO:0042981 335 0.013
learning GO:0007612 33 0.013
histone methylation GO:0016571 3 0.013
retina morphogenesis in camera type eye GO:0060042 1 0.013
centrosome organization GO:0051297 1 0.013
response to metal ion GO:0010038 253 0.013
retinal cell programmed cell death GO:0046666 1 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.013
maintenance of protein location in cell GO:0032507 7 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
protein processing GO:0016485 68 0.013
response to monosaccharide GO:0034284 159 0.013
molting cycle GO:0042303 3 0.013
regulation of protein phosphorylation GO:0001932 183 0.012
regulation of neurogenesis GO:0050767 247 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
negative regulation of cell development GO:0010721 82 0.012
regulation of dna templated transcription elongation GO:0032784 4 0.012
cell cycle phase transition GO:0044770 21 0.012
regulation of nervous system development GO:0051960 264 0.012
mitotic cell cycle process GO:1903047 35 0.012
Fly
endocytic recycling GO:0032456 2 0.012
negative regulation of developmental process GO:0051093 125 0.012
mitochondrion organization GO:0007005 35 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
regulation of proteolysis GO:0030162 66 0.012
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
protein phosphorylation GO:0006468 345 0.011
response to ethanol GO:0045471 162 0.011
organic acid metabolic process GO:0006082 292 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of cell death GO:0010942 184 0.011
response to decreased oxygen levels GO:0036293 237 0.011
regulation of cell cycle process GO:0010564 31 0.011
response to nutrient levels GO:0031667 370 0.011
camera type eye morphogenesis GO:0048593 2 0.011
response to cytokine GO:0034097 215 0.011
positive regulation of protein complex assembly GO:0031334 18 0.011
cellular amine metabolic process GO:0044106 38 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.010
regulation of response to stress GO:0080134 126 0.010
respiratory system development GO:0060541 45 0.010
female sex differentiation GO:0046660 59 0.010
response to acid chemical GO:0001101 222 0.010

Psmc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017