Rattus norvegicus

0 known processes

Psmc4

proteasome (prosome, macropain) 26S subunit, ATPase, 4

(Aliases: Tbp7)

Psmc4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic spindle organization GO:0007052 2 0.446
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.364
Yeast
ubiquitin dependent protein catabolic process GO:0006511 14 0.346
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.292
spindle organization GO:0007051 2 0.258
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 3 0.253
Yeast
cellular response to stress GO:0033554 269 0.188
Fly
cell cycle GO:0007049 101 0.177
modification dependent macromolecule catabolic process GO:0043632 14 0.174
Yeast
proteasomal protein catabolic process GO:0010498 8 0.154
cellular protein catabolic process GO:0044257 19 0.145
Yeast
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 3 0.134
Yeast
macromolecule catabolic process GO:0009057 58 0.130
Yeast
dna templated transcription initiation GO:0006352 4 0.127
Yeast
negative regulation of translational initiation GO:0045947 5 0.125
modification dependent protein catabolic process GO:0019941 14 0.124
Yeast
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 3 0.124
Yeast
organelle organization GO:0006996 266 0.122
proteolysis GO:0006508 175 0.120
Yeast Fly
organic substance catabolic process GO:1901575 316 0.109
Yeast
protein catabolic process GO:0030163 30 0.109
Yeast
macromolecular complex assembly GO:0065003 273 0.108
Yeast
cellular catabolic process GO:0044248 295 0.104
Yeast
negative regulation of biosynthetic process GO:0009890 168 0.099
macromolecule localization GO:0033036 252 0.097
macromolecular complex subunit organization GO:0043933 339 0.097
Yeast
negative regulation of cellular metabolic process GO:0031324 281 0.094
centrosome organization GO:0051297 1 0.084
ribonucleoside catabolic process GO:0042454 126 0.082
cytoskeleton organization GO:0007010 111 0.077
regulation of retinal cell programmed cell death GO:0046668 1 0.075
transcription initiation from rna polymerase ii promoter GO:0006367 3 0.075
Yeast
reproduction GO:0000003 245 0.074
Worm
chromosome segregation GO:0007059 2 0.071
cellular macromolecule catabolic process GO:0044265 29 0.070
Yeast
atp catabolic process GO:0006200 54 0.069
multicellular organism reproduction GO:0032504 233 0.066
protein complex assembly GO:0006461 263 0.065
Yeast
protein complex biogenesis GO:0070271 263 0.063
Yeast
cellular component biogenesis GO:0044085 368 0.063
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 122 0.061
cellular protein complex assembly GO:0043623 44 0.060
Yeast
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.058
Yeast
microtubule organizing center organization GO:0031023 1 0.058
nucleotide catabolic process GO:0009166 139 0.057
organophosphate catabolic process GO:0046434 148 0.056
purine nucleoside monophosphate catabolic process GO:0009128 55 0.052
ribonucleotide catabolic process GO:0009261 136 0.050
protein complex subunit organization GO:0071822 302 0.050
Yeast
positive regulation of catalytic activity GO:0043085 184 0.047
regulation of cell development GO:0060284 263 0.043
rna metabolic process GO:0016070 406 0.043
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 122 0.043
protein localization GO:0008104 191 0.040
organonitrogen compound catabolic process GO:1901565 179 0.040
purine nucleoside triphosphate metabolic process GO:0009144 141 0.039
single organism organelle organization GO:1902589 180 0.039
negative regulation of translation in response to stress GO:0032055 5 0.039
regulation of cellular component organization GO:0051128 368 0.038
Yeast
dna templated transcriptional preinitiation complex assembly GO:0070897 3 0.038
Yeast
transcription from rna polymerase ii promoter GO:0006366 252 0.038
Yeast
purine ribonucleotide metabolic process GO:0009150 227 0.037
cellular macromolecular complex assembly GO:0034622 58 0.037
Yeast
organelle assembly GO:0070925 22 0.037
multicellular organismal reproductive process GO:0048609 233 0.037
heterocycle catabolic process GO:0046700 167 0.036
carbohydrate derivative catabolic process GO:1901136 147 0.036
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.036
regulation of cell differentiation GO:0045595 320 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.036
Yeast
cell cycle process GO:0022402 57 0.035
cellular component assembly GO:0022607 360 0.035
Yeast
regulation of cellular localization GO:0060341 263 0.034
reproductive process GO:0022414 372 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.033
response to peptide hormone GO:0043434 278 0.033
microtubule based process GO:0007017 36 0.033
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 3 0.033
catabolic process GO:0009056 351 0.033
Yeast
response to peptide GO:1901652 292 0.032
nucleoside monophosphate catabolic process GO:0009125 56 0.031
protein transport GO:0015031 132 0.031
purine nucleoside catabolic process GO:0006152 124 0.031
regulation of rna biosynthetic process GO:2001141 381 0.030
Yeast
glycosyl compound catabolic process GO:1901658 126 0.030
positive regulation of dna templated transcription initiation GO:2000144 3 0.030
Yeast
response to inorganic substance GO:0010035 377 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
Yeast
single organism catabolic process GO:0044712 283 0.029
histone methylation GO:0016571 3 0.029
regulation of protein metabolic process GO:0051246 289 0.028
nucleobase containing compound catabolic process GO:0034655 152 0.028
posttranscriptional regulation of gene expression GO:0010608 37 0.027
purine containing compound catabolic process GO:0072523 138 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
secretion by cell GO:0032940 248 0.027
rna biosynthetic process GO:0032774 380 0.027
Yeast
chromatin modification GO:0016568 33 0.026
eye morphogenesis GO:0048592 4 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
embryo development GO:0009790 49 0.026
Mouse Worm
purine ribonucleoside catabolic process GO:0046130 124 0.025
purine nucleotide catabolic process GO:0006195 136 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.024
regulation of cell proliferation GO:0042127 359 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
transcription dna templated GO:0006351 377 0.023
Yeast
aromatic compound catabolic process GO:0019439 168 0.023
establishment of protein localization GO:0045184 141 0.023
cellular protein localization GO:0034613 122 0.022
cytoskeleton dependent cytokinesis GO:0061640 2 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
Yeast
neuron projection development GO:0031175 273 0.022
transmembrane transport GO:0055085 412 0.022
response to glucose GO:0009749 136 0.021
apoptotic process GO:0006915 381 0.021
mitotic cell cycle process GO:1903047 35 0.021
organophosphate metabolic process GO:0019637 370 0.021
secretion GO:0046903 307 0.021
cellular nitrogen compound catabolic process GO:0044270 163 0.021
reproductive structure development GO:0048608 128 0.021
regulation of catabolic process GO:0009894 113 0.021
cellular amine metabolic process GO:0044106 38 0.021
amine metabolic process GO:0009308 38 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
Yeast
regulation of nucleic acid templated transcription GO:1903506 380 0.020
Yeast
membrane organization GO:0061024 94 0.020
positive regulation of cell death GO:0010942 184 0.020
single organism cellular localization GO:1902580 102 0.019
regulation of translation in response to stress GO:0043555 5 0.019
purine nucleoside monophosphate metabolic process GO:0009126 84 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
Yeast
regulation of translation GO:0006417 27 0.019
cellular ketone metabolic process GO:0042180 51 0.019
mitotic cell cycle GO:0000278 49 0.019
positive regulation of signaling GO:0023056 270 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
positive regulation of molecular function GO:0044093 230 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
Yeast
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
hematopoietic progenitor cell differentiation GO:0002244 2 0.018
vesicle mediated transport GO:0016192 181 0.018
rna catabolic process GO:0006401 3 0.018
biological adhesion GO:0022610 110 0.018
programmed cell death GO:0012501 392 0.018
regulation of proteasomal protein catabolic process GO:0061136 4 0.018
microtubule cytoskeleton organization GO:0000226 25 0.018
intracellular transport GO:0046907 185 0.018
single organism reproductive process GO:0044702 297 0.017
intracellular signal transduction GO:0035556 314 0.017
positive regulation of cellular catabolic process GO:0031331 71 0.017
aging GO:0007568 241 0.017
Worm
cellular response to dna damage stimulus GO:0006974 19 0.017
Fly
regulation of rna metabolic process GO:0051252 391 0.017
Yeast
gonad development GO:0008406 104 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
sexual reproduction GO:0019953 148 0.017
response to metal ion GO:0010038 253 0.016
response to ethanol GO:0045471 162 0.016
response to ketone GO:1901654 182 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
centrosome cycle GO:0007098 1 0.016
regulation of signal transduction GO:0009966 318 0.016
regulation of nucleotide catabolic process GO:0030811 65 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
purine containing compound metabolic process GO:0072521 253 0.015
male gamete generation GO:0048232 99 0.015
nucleocytoplasmic transport GO:0006913 48 0.015
oxoacid metabolic process GO:0043436 290 0.015
chromosome organization GO:0051276 36 0.015
tube development GO:0035295 89 0.015
translation GO:0006412 35 0.015
positive regulation of neuron death GO:1901216 43 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
peptidyl amino acid modification GO:0018193 126 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
neuron differentiation GO:0030182 368 0.014
positive regulation of cell communication GO:0010647 271 0.014
cell projection organization GO:0030030 302 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
double strand break repair GO:0006302 1 0.014
multi organism reproductive process GO:0044703 262 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
Yeast
ribonucleotide metabolic process GO:0009259 231 0.014
spermatogenesis GO:0007283 99 0.014
cellular response to unfolded protein GO:0034620 2 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
Yeast
negative regulation of rna biosynthetic process GO:1902679 118 0.013
positive regulation of gene expression GO:0010628 244 0.013
Yeast
positive regulation of apoptotic process GO:0043065 154 0.013
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.013
Yeast
organelle fission GO:0048285 25 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
cell adhesion GO:0007155 110 0.013
response to endoplasmic reticulum stress GO:0034976 10 0.013
maintenance of location GO:0051235 17 0.013
negative regulation of metabolic process GO:0009892 331 0.013
cytoplasmic transport GO:0016482 115 0.013
sex differentiation GO:0007548 113 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
Yeast
growth GO:0040007 165 0.013
regulation of organelle organization GO:0033043 80 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
nucleic acid templated transcription GO:0097659 379 0.013
Yeast
negative regulation of multicellular organismal process GO:0051241 203 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
cellular response to oxygen levels GO:0071453 60 0.013
tissue development GO:0009888 252 0.012
development of primary sexual characteristics GO:0045137 107 0.012
ovulation cycle GO:0042698 67 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
er nucleus signaling pathway GO:0006984 3 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
Yeast
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of cell growth GO:0001558 85 0.012
nucleoside catabolic process GO:0009164 126 0.012
ras protein signal transduction GO:0007265 29 0.011
cellular macromolecule localization GO:0070727 122 0.011
regulation of neurogenesis GO:0050767 247 0.011
response to calcium ion GO:0051592 59 0.011
amino acid activation GO:0043038 3 0.011
regulation of molecular function GO:0065009 398 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
cell projection morphogenesis GO:0048858 123 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
regulation of catalytic activity GO:0050790 304 0.011
protein polymerization GO:0051258 22 0.011
response to starvation GO:0042594 59 0.011
embryo development ending in birth or egg hatching GO:0009792 22 0.011
Mouse Worm
regulation of cellular ketone metabolic process GO:0010565 27 0.010
respiratory system development GO:0060541 45 0.010
regulation of hydrolase activity GO:0051336 143 0.010
regulation of neuron projection development GO:0010975 161 0.010
positive regulation of protein modification process GO:0031401 142 0.010
cellular response to topologically incorrect protein GO:0035967 3 0.010
neuron development GO:0048666 286 0.010
positive regulation of catabolic process GO:0009896 78 0.010

Psmc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015