Rattus norvegicus

61 known processes

Ptges3

prostaglandin E synthase 3 (cytosolic)

(Aliases: RGD1561913,MGC188278)

Ptges3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule catabolic process GO:0044265 29 0.273
protein refolding GO:0042026 3 0.253
Human
rna metabolic process GO:0016070 406 0.233
macromolecule catabolic process GO:0009057 58 0.213
macromolecular complex assembly GO:0065003 273 0.213
protein complex biogenesis GO:0070271 263 0.201
protein complex subunit organization GO:0071822 302 0.199
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.170
cellular component assembly GO:0022607 360 0.169
cellular component biogenesis GO:0044085 368 0.163
modification dependent macromolecule catabolic process GO:0043632 14 0.147
modification dependent protein catabolic process GO:0019941 14 0.131
regulation of transcription dna templated GO:0006355 374 0.123
protein localization GO:0008104 191 0.120
macromolecular complex subunit organization GO:0043933 339 0.111
protein ubiquitination GO:0016567 28 0.106
regulation of rna metabolic process GO:0051252 391 0.098
cytoskeleton organization GO:0007010 111 0.096
nucleic acid templated transcription GO:0097659 379 0.092
protein transport GO:0015031 132 0.083
negative regulation of metabolic process GO:0009892 331 0.082
rna biosynthetic process GO:0032774 380 0.081
regulation of protein transport GO:0051223 68 0.080
regulation of programmed cell death GO:0043067 341 0.080
programmed cell death GO:0012501 392 0.074
er associated ubiquitin dependent protein catabolic process GO:0030433 1 0.072
regulation of cellular localization GO:0060341 263 0.072
transcription dna templated GO:0006351 377 0.071
protein catabolic process GO:0030163 30 0.070
intracellular transport GO:0046907 185 0.069
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.069
organelle organization GO:0006996 266 0.068
regulation of rna biosynthetic process GO:2001141 381 0.068
negative regulation of cellular metabolic process GO:0031324 281 0.067
positive regulation of transport GO:0051050 245 0.066
regulation of nucleic acid templated transcription GO:1903506 380 0.064
macromolecule localization GO:0033036 252 0.063
cardiovascular system development GO:0072358 134 0.062
myosin filament assembly GO:0031034 1 0.058
negative regulation of transcription dna templated GO:0045892 116 0.058
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.057
catabolic process GO:0009056 351 0.056
nucleocytoplasmic transport GO:0006913 48 0.055
negative regulation of gene expression GO:0010629 199 0.052
multicellular organismal reproductive process GO:0048609 233 0.051
cellular macromolecular complex assembly GO:0034622 58 0.050
cellular response to stress GO:0033554 269 0.050
cellular protein complex assembly GO:0043623 44 0.050
single organism organelle organization GO:1902589 180 0.048
positive regulation of protein transport GO:0051222 41 0.047
cytoplasmic transport GO:0016482 115 0.045
regulation of apoptotic process GO:0042981 335 0.045
multi organism reproductive process GO:0044703 262 0.044
protein complex assembly GO:0006461 263 0.043
regulation of proteasomal protein catabolic process GO:0061136 4 0.043
cellular response to organic cyclic compound GO:0071407 202 0.042
regulation of protein import into nucleus GO:0042306 24 0.040
reproductive process GO:0022414 372 0.038
microtubule organizing center organization GO:0031023 1 0.038
proteolysis GO:0006508 175 0.038
dna metabolic process GO:0006259 96 0.037
Human
apoptotic process GO:0006915 381 0.036
organic substance catabolic process GO:1901575 316 0.035
regulation of establishment of protein localization GO:0070201 69 0.035
single organism reproductive process GO:0044702 297 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.034
cellular protein catabolic process GO:0044257 19 0.033
reproduction GO:0000003 245 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
homeostatic process GO:0042592 331 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.032
positive regulation of protein metabolic process GO:0051247 178 0.031
cellular catabolic process GO:0044248 295 0.031
cellular response to oxygen containing compound GO:1901701 386 0.030
response to growth factor GO:0070848 189 0.029
regulation of nucleocytoplasmic transport GO:0046822 28 0.028
negative regulation of rna metabolic process GO:0051253 123 0.028
establishment of protein localization GO:0045184 141 0.027
response to heat GO:0009408 60 0.027
spindle organization GO:0007051 2 0.027
regulation of protein targeting GO:1903533 28 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
regulation of protein localization GO:0032880 81 0.026
regulation of response to stress GO:0080134 126 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
dna replication GO:0006260 37 0.025
Human
circulatory system process GO:0003013 183 0.025
actin filament based process GO:0030029 86 0.025
organelle assembly GO:0070925 22 0.025
positive regulation of cellular component organization GO:0051130 200 0.024
single organism cellular localization GO:1902580 102 0.024
mitotic spindle organization GO:0007052 2 0.024
ubiquitin dependent protein catabolic process GO:0006511 14 0.024
regulation of striated muscle contraction GO:0006942 21 0.023
muscle system process GO:0003012 115 0.023
actin cytoskeleton organization GO:0030036 73 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
cellular protein localization GO:0034613 122 0.023
regulation of secretion GO:0051046 224 0.022
regulation of protein metabolic process GO:0051246 289 0.022
single organism intracellular transport GO:1902582 166 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
positive regulation of dna metabolic process GO:0051054 39 0.022
multicellular organism reproduction GO:0032504 233 0.022
trna metabolic process GO:0006399 4 0.022
sexual reproduction GO:0019953 148 0.022
ncrna processing GO:0034470 3 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
regulation of intracellular transport GO:0032386 65 0.021
cellular response to dna damage stimulus GO:0006974 19 0.020
regulation of protein catabolic process GO:0042176 16 0.020
regulation of cell differentiation GO:0045595 320 0.020
cellular amine metabolic process GO:0044106 38 0.020
negative regulation of phosphorus metabolic process GO:0010563 80 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
somatic diversification of immunoglobulins involved in immune response GO:0002208 1 0.019
negative regulation of apoptotic process GO:0043066 181 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.018
regulation of dna metabolic process GO:0051052 60 0.018
negative regulation of neuron apoptotic process GO:0043524 45 0.017
centrosome organization GO:0051297 1 0.017
vesicle mediated transport GO:0016192 181 0.017
regulation of cellular component organization GO:0051128 368 0.017
response to oxidative stress GO:0006979 186 0.017
proteasomal protein catabolic process GO:0010498 8 0.017
nuclear transport GO:0051169 49 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
cellular response to endogenous stimulus GO:0071495 377 0.016
nitrogen compound transport GO:0071705 229 0.016
endocytosis GO:0006897 84 0.016
neuron death GO:0070997 127 0.016
regulation of cell projection organization GO:0031344 175 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
negative regulation of neuron death GO:1901215 69 0.015
response to inorganic substance GO:0010035 377 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
regulation of neuron apoptotic process GO:0043523 83 0.015
immunoglobulin mediated immune response GO:0016064 4 0.015
protein localization to organelle GO:0033365 57 0.015
ribonucleoprotein complex biogenesis GO:0022613 10 0.015
regulation of homeostatic process GO:0032844 101 0.015
cellular homeostasis GO:0019725 252 0.015
receptor mediated endocytosis GO:0006898 42 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
regulation of intracellular protein transport GO:0033157 34 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
cell type specific apoptotic process GO:0097285 134 0.014
positive regulation of developmental process GO:0051094 283 0.014
protein localization to nucleus GO:0034504 39 0.014
male gamete generation GO:0048232 99 0.014
ossification GO:0001503 70 0.014
gamete generation GO:0007276 124 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
blood circulation GO:0008015 183 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
regulation of cytoplasmic transport GO:1903649 54 0.014
positive regulation of cardiac muscle contraction GO:0060452 4 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
localization of cell GO:0051674 202 0.014
regulation of protein modification process GO:0031399 194 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
response to oxygen levels GO:0070482 265 0.013
transmembrane transport GO:0055085 412 0.013
rna localization GO:0006403 4 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
nucleosome organization GO:0034728 1 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
positive regulation of cellular component biogenesis GO:0044089 55 0.012
response to metal ion GO:0010038 253 0.012
regulation of interferon gamma production GO:0032649 3 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
cell cycle process GO:0022402 57 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
response to hypoxia GO:0001666 231 0.012
positive regulation of cytoplasmic transport GO:1903651 32 0.012
regulation of neuron projection development GO:0010975 161 0.012
anterior posterior pattern specification GO:0009952 1 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 3 0.012
response to estrogen GO:0043627 232 0.012
regulation of catalytic activity GO:0050790 304 0.012
microtubule based process GO:0007017 36 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
toxin transport GO:1901998 3 0.011
protein modification by small protein conjugation or removal GO:0070647 35 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
negative regulation of cell death GO:0060548 229 0.011
signal release GO:0023061 145 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
regulation of neuron death GO:1901214 115 0.011
cell motility GO:0048870 202 0.011
male mating behavior GO:0060179 3 0.011
organophosphate metabolic process GO:0019637 370 0.011
regulation of neuron differentiation GO:0045664 208 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
b cell activation involved in immune response GO:0002312 1 0.010
regulation of cardiac muscle contraction GO:0055117 17 0.010
regulation of molecular function GO:0065009 398 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
tissue development GO:0009888 252 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
cell cell signaling GO:0007267 335 0.010
chemosensory behavior GO:0007635 2 0.010
triglyceride homeostasis GO:0070328 2 0.010

Ptges3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 0 0.017
cognitive disorder DOID:1561 0 0.017