Rattus norvegicus

4 known processes

Ptgr1

prostaglandin reductase 1

(Aliases: Ltb4dh,Dig1)

Ptgr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.493
lipid metabolic process GO:0006629 283 0.362
carboxylic acid metabolic process GO:0019752 289 0.344
organic acid metabolic process GO:0006082 292 0.330
cellular lipid metabolic process GO:0044255 208 0.265
monocarboxylic acid metabolic process GO:0032787 152 0.247
single organism catabolic process GO:0044712 283 0.181
oxidation reduction process GO:0055114 304 0.154
cellular amino acid metabolic process GO:0006520 107 0.151
response to inorganic substance GO:0010035 377 0.111
fatty acid metabolic process GO:0006631 99 0.110
organic substance catabolic process GO:1901575 316 0.106
organic hydroxy compound metabolic process GO:1901615 115 0.104
cellular catabolic process GO:0044248 295 0.102
response to extracellular stimulus GO:0009991 380 0.096
single organism biosynthetic process GO:0044711 342 0.088
response to insulin GO:0032868 133 0.088
response to peptide GO:1901652 292 0.087
response to peptide hormone GO:0043434 278 0.086
catabolic process GO:0009056 351 0.084
regulation of hormone levels GO:0010817 187 0.076
organophosphate metabolic process GO:0019637 370 0.074
response to nutrient levels GO:0031667 370 0.073
small molecule catabolic process GO:0044282 59 0.072
response to glucocorticoid GO:0051384 223 0.070
cellular response to oxygen containing compound GO:1901701 386 0.068
lipid oxidation GO:0034440 30 0.065
carbohydrate derivative metabolic process GO:1901135 346 0.065
response to toxic substance GO:0009636 133 0.059
response to acid chemical GO:0001101 222 0.058
organic acid biosynthetic process GO:0016053 83 0.057
response to corticosteroid GO:0031960 235 0.057
cellular ketone metabolic process GO:0042180 51 0.056
response to nutrient GO:0007584 248 0.056
response to metal ion GO:0010038 253 0.055
protein oligomerization GO:0051259 191 0.055
fatty acid beta oxidation GO:0006635 22 0.055
retinal metabolic process GO:0042574 3 0.053
response to vitamin GO:0033273 131 0.053
cofactor metabolic process GO:0051186 95 0.052
response to molecule of bacterial origin GO:0002237 194 0.052
cellular hormone metabolic process GO:0034754 49 0.051
organ regeneration GO:0031100 101 0.049
protein complex subunit organization GO:0071822 302 0.047
cell projection organization GO:0030030 302 0.047
response to lipopolysaccharide GO:0032496 191 0.047
cellular response to organonitrogen compound GO:0071417 197 0.046
regulation of cell proliferation GO:0042127 359 0.045
protein complex biogenesis GO:0070271 263 0.045
nucleoside phosphate metabolic process GO:0006753 283 0.044
small molecule biosynthetic process GO:0044283 124 0.044
neuron differentiation GO:0030182 368 0.043
nucleobase containing small molecule metabolic process GO:0055086 316 0.043
response to ketone GO:1901654 182 0.042
circulatory system process GO:0003013 183 0.042
response to transition metal nanoparticle GO:1990267 122 0.042
cellular component assembly GO:0022607 360 0.042
macromolecular complex subunit organization GO:0043933 339 0.041
carboxylic acid biosynthetic process GO:0046394 83 0.041
liver development GO:0001889 90 0.041
hormone metabolic process GO:0042445 69 0.040
coenzyme metabolic process GO:0006732 86 0.040
tissue development GO:0009888 252 0.040
anatomical structure morphogenesis GO:0009653 298 0.040
organelle organization GO:0006996 266 0.040
regeneration GO:0031099 163 0.039
lipid catabolic process GO:0016042 46 0.039
single organism reproductive process GO:0044702 297 0.038
response to ethanol GO:0045471 162 0.038
cellular response to endogenous stimulus GO:0071495 377 0.038
macromolecular complex assembly GO:0065003 273 0.038
response to estrogen GO:0043627 232 0.038
cellular response to nitrogen compound GO:1901699 210 0.037
cation transport GO:0006812 382 0.037
cellular response to lipid GO:0071396 201 0.037
terpenoid metabolic process GO:0006721 37 0.036
hepaticobiliary system development GO:0061008 90 0.035
single organism carbohydrate metabolic process GO:0044723 118 0.035
cellular lipid catabolic process GO:0044242 37 0.035
reproductive process GO:0022414 372 0.034
steroid metabolic process GO:0008202 73 0.034
alcohol metabolic process GO:0006066 77 0.034
carbohydrate metabolic process GO:0005975 130 0.034
cellular response to peptide hormone stimulus GO:0071375 120 0.034
positive regulation of developmental process GO:0051094 283 0.034
cellular response to hormone stimulus GO:0032870 247 0.033
neuron development GO:0048666 286 0.033
nucleotide metabolic process GO:0009117 279 0.033
response to biotic stimulus GO:0009607 226 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
carboxylic acid catabolic process GO:0046395 49 0.032
monocarboxylic acid catabolic process GO:0072329 28 0.032
cellular component biogenesis GO:0044085 368 0.032
epithelium development GO:0060429 96 0.032
aging GO:0007568 241 0.032
isoprenoid metabolic process GO:0006720 45 0.031
organophosphate biosynthetic process GO:0090407 143 0.031
organic acid catabolic process GO:0016054 49 0.031
regulation of programmed cell death GO:0043067 341 0.031
response to estradiol GO:0032355 164 0.030
response to oxygen levels GO:0070482 265 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.030
protein complex assembly GO:0006461 263 0.030
metal ion transport GO:0030001 289 0.030
cellular modified amino acid metabolic process GO:0006575 61 0.030
organic cyclic compound catabolic process GO:1901361 175 0.029
regulation of cell development GO:0060284 263 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
cellular amine metabolic process GO:0044106 38 0.029
response to cadmium ion GO:0046686 35 0.029
central nervous system development GO:0007417 311 0.029
protein phosphorylation GO:0006468 345 0.028
regulation of molecular function GO:0065009 398 0.028
cellular response to growth factor stimulus GO:0071363 162 0.028
halogenated hydrocarbon metabolic process GO:0042197 4 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
response to growth factor GO:0070848 189 0.027
heart morphogenesis GO:0003007 3 0.027
neuron projection development GO:0031175 273 0.027
blood circulation GO:0008015 183 0.027
regulation of system process GO:0044057 208 0.027
response to decreased oxygen levels GO:0036293 237 0.027
programmed cell death GO:0012501 392 0.026
intracellular signal transduction GO:0035556 314 0.026
response to external biotic stimulus GO:0043207 221 0.026
glutathione metabolic process GO:0006749 15 0.026
positive regulation of cell proliferation GO:0008284 249 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
intracellular transport GO:0046907 185 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
glycosyl compound metabolic process GO:1901657 182 0.025
cellular response to stress GO:0033554 269 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
brain development GO:0007420 247 0.025
cellular response to organic cyclic compound GO:0071407 202 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
gland development GO:0048732 155 0.024
cellular homeostasis GO:0019725 252 0.024
apoptotic process GO:0006915 381 0.024
regulation of signal transduction GO:0009966 318 0.024
response to carbohydrate GO:0009743 183 0.024
response to oxidative stress GO:0006979 186 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
regulation of neuron differentiation GO:0045664 208 0.024
reproduction GO:0000003 245 0.023
chemical homeostasis GO:0048878 292 0.023
regulation of apoptotic process GO:0042981 335 0.023
secretion GO:0046903 307 0.023
amine metabolic process GO:0009308 38 0.023
neurological system process GO:0050877 219 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
nucleoside phosphate biosynthetic process GO:1901293 102 0.022
sulfur compound metabolic process GO:0006790 70 0.022
homeostatic process GO:0042592 331 0.022
transcription dna templated GO:0006351 377 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
cellular chemical homeostasis GO:0055082 247 0.022
cellular amide metabolic process GO:0043603 44 0.022
alpha amino acid metabolic process GO:1901605 71 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
positive regulation of signal transduction GO:0009967 175 0.022
cellular amino acid biosynthetic process GO:0008652 32 0.021
regulation of catalytic activity GO:0050790 304 0.021
head development GO:0060322 247 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
response to wounding GO:0009611 254 0.021
regulation of nervous system development GO:0051960 264 0.021
amide biosynthetic process GO:0043604 10 0.021
glutathione biosynthetic process GO:0006750 3 0.021
diterpenoid metabolic process GO:0016101 33 0.021
positive regulation of signaling GO:0023056 270 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
response to bacterium GO:0009617 200 0.021
negative regulation of cell death GO:0060548 229 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
cellular response to peptide GO:1901653 133 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
cellular response to steroid hormone stimulus GO:0071383 93 0.020
response to other organism GO:0051707 220 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
response to radiation GO:0009314 137 0.020
single organism intracellular transport GO:1902582 166 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
aromatic compound catabolic process GO:0019439 168 0.020
cellular component morphogenesis GO:0032989 155 0.019
cellular component movement GO:0006928 248 0.019
single organism organelle organization GO:1902589 180 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
purine containing compound metabolic process GO:0072521 253 0.019
response to hypoxia GO:0001666 231 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
cellular response to glucocorticoid stimulus GO:0071385 68 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
rhythmic process GO:0048511 156 0.019
dicarboxylic acid metabolic process GO:0043648 42 0.019
negative regulation of metabolic process GO:0009892 331 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
rna biosynthetic process GO:0032774 380 0.018
cellular response to insulin stimulus GO:0032869 81 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
cellular response to corticosteroid stimulus GO:0071384 69 0.018
regulation of secretion GO:0051046 224 0.018
regulation of transcription dna templated GO:0006355 374 0.018
anion transport GO:0006820 178 0.017
positive regulation of transport GO:0051050 245 0.017
regulation of secretion by cell GO:1903530 208 0.017
heterocycle catabolic process GO:0046700 167 0.017
peptide biosynthetic process GO:0043043 3 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
regulation of cell differentiation GO:0045595 320 0.017
secretion by cell GO:0032940 248 0.017
membrane organization GO:0061024 94 0.017
regulation of protein metabolic process GO:0051246 289 0.017
response to alkaloid GO:0043279 132 0.017
vesicle mediated transport GO:0016192 181 0.017
inflammatory response GO:0006954 150 0.017
glial cell differentiation GO:0010001 65 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
response to monosaccharide GO:0034284 159 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
regulation of membrane potential GO:0042391 110 0.016
regulation of phosphorylation GO:0042325 248 0.016
alpha amino acid biosynthetic process GO:1901607 23 0.016
regulation of response to external stimulus GO:0032101 106 0.016
regulation of neurogenesis GO:0050767 247 0.016
positive regulation of molecular function GO:0044093 230 0.016
regulation of neuron projection development GO:0010975 161 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
negative regulation of cell communication GO:0010648 158 0.016
single organism cellular localization GO:1902580 102 0.016
response to amino acid GO:0043200 75 0.016
cellular ion homeostasis GO:0006873 184 0.016
regulation of blood pressure GO:0008217 83 0.016
regulation of rna metabolic process GO:0051252 391 0.016
positive regulation of cell development GO:0010720 176 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
fatty acid oxidation GO:0019395 29 0.015
regulation of cellular component organization GO:0051128 368 0.015
cellular response to ketone GO:1901655 51 0.015
macromolecule localization GO:0033036 252 0.015
fatty acid catabolic process GO:0009062 26 0.015
leydig cell differentiation GO:0033327 8 0.015
lipid biosynthetic process GO:0008610 128 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
nonribosomal peptide biosynthetic process GO:0019184 3 0.015
neuronal action potential GO:0019228 35 0.015
urogenital system development GO:0001655 78 0.015
negative regulation of transport GO:0051051 136 0.015
multicellular organismal signaling GO:0035637 44 0.015
response to glucose GO:0009749 136 0.015
ion transmembrane transport GO:0034220 365 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
regulation of cellular localization GO:0060341 263 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
regulation of body fluid levels GO:0050878 90 0.015
anterior posterior pattern specification GO:0009952 1 0.015
establishment of protein localization GO:0045184 141 0.015
peptide metabolic process GO:0006518 32 0.014
positive regulation of cell communication GO:0010647 271 0.014
protein homooligomerization GO:0051260 91 0.014
regulation of nucleic acid templated transcription GO:1903506 380 0.014
nucleic acid templated transcription GO:0097659 379 0.014
reproductive structure development GO:0048608 128 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
multicellular organism reproduction GO:0032504 233 0.014
multi organism reproductive process GO:0044703 262 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
cell cell signaling GO:0007267 335 0.014
nucleoside metabolic process GO:0009116 179 0.014
cellular response to oxidative stress GO:0034599 76 0.014
nitrogen compound transport GO:0071705 229 0.014
action potential GO:0001508 54 0.014
neuron death GO:0070997 127 0.014
chromosome segregation GO:0007059 2 0.014
regulation of cell migration GO:0030334 128 0.014
defense response GO:0006952 194 0.014
reproductive system development GO:0061458 128 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
regulation of locomotion GO:0040012 148 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
single organism membrane organization GO:0044802 74 0.013
glial cell development GO:0021782 19 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
wound healing GO:0042060 122 0.013
epithelial cell differentiation GO:0030855 71 0.013
developmental process involved in reproduction GO:0003006 159 0.013
regulation of cell projection organization GO:0031344 175 0.013
metal ion homeostasis GO:0055065 186 0.013
positive regulation of gene expression GO:0010628 244 0.013
protein heterooligomerization GO:0051291 89 0.013
gliogenesis GO:0042063 93 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
cellular cation homeostasis GO:0030003 180 0.013
sensory perception GO:0007600 101 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
peptidyl amino acid modification GO:0018193 126 0.013
protein localization GO:0008104 191 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
negative regulation of signaling GO:0023057 157 0.013
muscle contraction GO:0006936 88 0.013
renal system development GO:0072001 67 0.012
ras protein signal transduction GO:0007265 29 0.012
locomotion GO:0040011 237 0.012
cell motility GO:0048870 202 0.012
immune system process GO:0002376 204 0.012
axis specification GO:0009798 4 0.012
rna metabolic process GO:0016070 406 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
organ morphogenesis GO:0009887 75 0.012
circulatory system development GO:0072359 134 0.012
cofactor biosynthetic process GO:0051188 28 0.012
retinoid metabolic process GO:0001523 24 0.012
synaptic transmission GO:0007268 235 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
growth GO:0040007 165 0.012
female pregnancy GO:0007565 122 0.012
biological adhesion GO:0022610 110 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
regulation of homeostatic process GO:0032844 101 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
kidney development GO:0001822 67 0.012
transmission of nerve impulse GO:0019226 42 0.012
cell type specific apoptotic process GO:0097285 134 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
positive regulation of cell death GO:0010942 184 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
negative regulation of secretion GO:0051048 82 0.011
hormone transport GO:0009914 121 0.011
cation transmembrane transport GO:0098655 263 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
nicotinamide nucleotide metabolic process GO:0046496 28 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
signal release GO:0023061 145 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
cellular response to xenobiotic stimulus GO:0071466 19 0.011
cardiac chamber development GO:0003205 1 0.011
muscle system process GO:0003012 115 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
response to hydrogen peroxide GO:0042542 89 0.011
establishment of tissue polarity GO:0007164 2 0.011
sexual reproduction GO:0019953 148 0.011
positive regulation of nervous system development GO:0051962 178 0.011
cardiovascular system development GO:0072358 134 0.011
purine containing compound catabolic process GO:0072523 138 0.011
negative regulation of molecular function GO:0044092 133 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
transmembrane transport GO:0055085 412 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.010
cellular response to external stimulus GO:0071496 118 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
monosaccharide metabolic process GO:0005996 61 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
cellular protein localization GO:0034613 122 0.010
xenobiotic metabolic process GO:0006805 19 0.010
negative regulation of neuron death GO:1901215 69 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
calcium ion homeostasis GO:0055074 162 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
cellular response to alcohol GO:0097306 87 0.010
cellular aldehyde metabolic process GO:0006081 11 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
sex differentiation GO:0007548 113 0.010
development of primary sexual characteristics GO:0045137 107 0.010
multi multicellular organism process GO:0044706 138 0.010
response to testosterone GO:0033574 55 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
regulation of neuron death GO:1901214 115 0.010
single organism behavior GO:0044708 130 0.010

Ptgr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.016
disease of anatomical entity DOID:7 0 0.012
musculoskeletal system disease DOID:17 0 0.012
cancer DOID:162 0 0.012
nervous system disease DOID:863 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011
gastrointestinal system disease DOID:77 0 0.010