Rattus norvegicus

19 known processes

Pttg1

pituitary tumor-transforming 1

(Aliases: Pttg)

Pttg1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to ddt GO:0046680 1 0.663
dna packaging GO:0006323 4 0.619
meiosis i GO:0007127 2 0.558
chromosome condensation GO:0030261 3 0.421
chromosome segregation GO:0007059 2 0.398
ventricular cardiac muscle cell development GO:0055015 2 0.359
cellular component biogenesis GO:0044085 368 0.334
cellular response to iron iii ion GO:0071283 3 0.328
macromolecular complex assembly GO:0065003 273 0.292
mitotic spindle organization GO:0007052 2 0.264
protein complex assembly GO:0006461 263 0.243
positive regulation of histone phosphorylation GO:0033129 3 0.232
meiotic cell cycle process GO:1903046 3 0.227
mitotic sister chromatid separation GO:0051306 1 0.221
protein complex subunit organization GO:0071822 302 0.221
cellular component assembly GO:0022607 360 0.221
regulation of proteasomal protein catabolic process GO:0061136 4 0.217
protein complex biogenesis GO:0070271 263 0.191
ventricular cardiac muscle cell differentiation GO:0055012 2 0.185
mitotic sister chromatid segregation GO:0000070 1 0.171
sister chromatid segregation GO:0000819 1 0.164
regulation of multicellular organismal development GO:2000026 376 0.158
protein localization to chromosome centromeric region GO:0071459 1 0.151
regulation of cell proliferation GO:0042127 359 0.147
single organism organelle organization GO:1902589 180 0.139
positive regulation of multicellular organismal process GO:0051240 387 0.138
protein localization GO:0008104 191 0.135
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.130
negative regulation of cell death GO:0060548 229 0.126
organelle organization GO:0006996 266 0.124
regulation of cellular component organization GO:0051128 368 0.122
macromolecular complex subunit organization GO:0043933 339 0.114
regulation of molecular function GO:0065009 398 0.111
macromolecule localization GO:0033036 252 0.108
establishment of organelle localization GO:0051656 37 0.099
positive regulation of developmental process GO:0051094 283 0.095
regulation of mrna 3 end processing GO:0031440 1 0.094
spindle organization GO:0007051 2 0.091
regulation of muscle tissue development GO:1901861 25 0.090
cellular protein localization GO:0034613 122 0.090
regulation of apoptotic process GO:0042981 335 0.086
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.082
reproduction GO:0000003 245 0.081
striated muscle cell proliferation GO:0014855 9 0.081
regulation of synapse maturation GO:0090128 2 0.080
regulation of catalytic activity GO:0050790 304 0.079
cellular catabolic process GO:0044248 295 0.077
cell cycle dna replication GO:0044786 1 0.075
cell cycle g1 s phase transition GO:0044843 13 0.074
cell cycle phase transition GO:0044770 21 0.074
regulation of cellular localization GO:0060341 263 0.073
growth GO:0040007 165 0.073
regeneration GO:0031099 163 0.071
cardiac cell development GO:0055006 16 0.071
cell cycle checkpoint GO:0000075 2 0.071
negative regulation of programmed cell death GO:0043069 183 0.068
neuron differentiation GO:0030182 368 0.068
regulation of organelle organization GO:0033043 80 0.065
cellular macromolecule localization GO:0070727 122 0.065
positive regulation of cellular protein metabolic process GO:0032270 167 0.064
regulation of cell differentiation GO:0045595 320 0.063
cellular response to oxygen containing compound GO:1901701 386 0.063
single organism reproductive process GO:0044702 297 0.062
cytoskeleton organization GO:0007010 111 0.062
negative regulation of macromolecule metabolic process GO:0010605 260 0.060
regulation of nervous system development GO:0051960 264 0.059
regulation of cell development GO:0060284 263 0.057
histone serine phosphorylation GO:0035404 1 0.056
regulation of phosphate metabolic process GO:0019220 349 0.056
positive regulation of phosphorus metabolic process GO:0010562 262 0.055
cellular component movement GO:0006928 248 0.055
macromolecule catabolic process GO:0009057 58 0.055
regulation of cardiac muscle tissue development GO:0055024 12 0.053
cellular response to stress GO:0033554 269 0.052
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.052
response to wounding GO:0009611 254 0.052
reproductive process GO:0022414 372 0.052
response to toxic substance GO:0009636 133 0.052
catabolic process GO:0009056 351 0.051
programmed cell death GO:0012501 392 0.051
rna metabolic process GO:0016070 406 0.051
apoptotic process GO:0006915 381 0.051
regulation of cell cycle GO:0051726 73 0.050
multi organism reproductive process GO:0044703 262 0.049
response to oxygen levels GO:0070482 265 0.049
sexual reproduction GO:0019953 148 0.049
cardiac muscle cell development GO:0055013 16 0.049
cytokinetic process GO:0032506 1 0.048
microtubule anchoring GO:0034453 1 0.048
dna metabolic process GO:0006259 96 0.048
response to metal ion GO:0010038 253 0.048
multicellular organismal reproductive process GO:0048609 233 0.048
positive regulation of phosphate metabolic process GO:0045937 262 0.048
negative regulation of microtubule depolymerization GO:0007026 3 0.047
cell cycle GO:0007049 101 0.047
regulation of transferase activity GO:0051338 123 0.047
protein phosphorylation GO:0006468 345 0.047
cytoskeleton dependent cytokinesis GO:0061640 2 0.047
positive regulation of synaptic plasticity GO:0031915 3 0.046
maintenance of location GO:0051235 17 0.046
regulation of phosphorus metabolic process GO:0051174 349 0.046
asymmetric stem cell division GO:0098722 2 0.045
negative regulation of apoptotic process GO:0043066 181 0.045
positive regulation of synapse maturation GO:0090129 2 0.045
peptidyl serine modification GO:0018209 34 0.045
muscle tissue development GO:0060537 58 0.044
response to mechanical stimulus GO:0009612 134 0.044
negative regulation of gene expression GO:0010629 199 0.044
positive regulation of cellular component organization GO:0051130 200 0.044
regulation of neuron projection development GO:0010975 161 0.044
chromosome organization GO:0051276 36 0.043
developmental growth GO:0048589 100 0.043
negative regulation of metabolic process GO:0009892 331 0.043
response to inorganic substance GO:0010035 377 0.042
multicellular organism reproduction GO:0032504 233 0.042
neuron development GO:0048666 286 0.042
negative regulation of chromosome organization GO:2001251 1 0.041
positive regulation of catalytic activity GO:0043085 184 0.041
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.040
regulation of meiotic cell cycle GO:0051445 3 0.040
positive regulation of cell proliferation GO:0008284 249 0.040
anatomical structure morphogenesis GO:0009653 298 0.039
regulation of phosphorylation GO:0042325 248 0.038
establishment of protein localization GO:0045184 141 0.038
regulation of mitotic sister chromatid separation GO:0010965 1 0.038
response to peptide GO:1901652 292 0.037
regulation of growth GO:0040008 105 0.037
histone phosphorylation GO:0016572 6 0.037
tissue regeneration GO:0042246 36 0.037
regulation of chromosome segregation GO:0051983 1 0.037
regulation of neuron differentiation GO:0045664 208 0.036
neuron projection development GO:0031175 273 0.036
wound healing GO:0042060 122 0.036
negative regulation of cell cycle phase transition GO:1901988 4 0.036
regulation of cell projection organization GO:0031344 175 0.036
microtubule polymerization or depolymerization GO:0031109 13 0.036
developmental process involved in reproduction GO:0003006 159 0.035
positive regulation of protein modification process GO:0031401 142 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
striated muscle tissue development GO:0014706 58 0.035
response to insecticide GO:0017085 21 0.034
peptidyl amino acid modification GO:0018193 126 0.034
positive regulation of protein phosphorylation GO:0001934 135 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
positive regulation of mrna metabolic process GO:1903313 4 0.034
regulation of protein metabolic process GO:0051246 289 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
purine containing compound metabolic process GO:0072521 253 0.033
metaphase plate congression GO:0051310 1 0.033
cardiovascular system development GO:0072358 134 0.033
cellular response to acid chemical GO:0071229 75 0.033
regulation of programmed cell death GO:0043067 341 0.033
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 3 0.033
regulation of cardiac muscle cell proliferation GO:0060043 6 0.033
peptidyl serine phosphorylation GO:0018105 33 0.032
vesicle mediated transport GO:0016192 181 0.032
response to peptide hormone GO:0043434 278 0.032
cell projection organization GO:0030030 302 0.031
chromatin organization GO:0006325 34 0.031
nucleic acid templated transcription GO:0097659 379 0.031
regulation of kinase activity GO:0043549 117 0.031
positive regulation of cellular catabolic process GO:0031331 71 0.031
regulation of sister chromatid segregation GO:0033045 1 0.031
intracellular signal transduction GO:0035556 314 0.031
regulation of catabolic process GO:0009894 113 0.031
regulation of neurogenesis GO:0050767 247 0.030
organic acid metabolic process GO:0006082 292 0.030
microtubule cytoskeleton organization GO:0000226 25 0.030
positive regulation of phosphorylation GO:0042327 177 0.030
centrosome organization GO:0051297 1 0.030
regulation of microtubule polymerization or depolymerization GO:0031110 12 0.030
positive regulation of cell communication GO:0010647 271 0.029
organic substance catabolic process GO:1901575 316 0.029
positive regulation of lipid catabolic process GO:0050996 4 0.029
circulatory system development GO:0072359 134 0.029
response to iron iii ion GO:0010041 6 0.029
cellular response to hormone stimulus GO:0032870 247 0.028
response to transition metal nanoparticle GO:1990267 122 0.028
negative regulation of protein metabolic process GO:0051248 114 0.027
negative regulation of cell differentiation GO:0045596 99 0.027
negative regulation of developmental process GO:0051093 125 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
cardiac muscle tissue growth GO:0055017 20 0.027
response to hypoxia GO:0001666 231 0.026
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.026
cell morphogenesis GO:0000902 142 0.026
response to decreased oxygen levels GO:0036293 237 0.026
cellular ketone metabolic process GO:0042180 51 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
regulation of heart growth GO:0060420 12 0.026
male meiosis GO:0007140 1 0.026
organic cyclic compound catabolic process GO:1901361 175 0.025
synaptic transmission GO:0007268 235 0.025
single organism catabolic process GO:0044712 283 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
reproductive structure development GO:0048608 128 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
striated muscle cell development GO:0055002 26 0.025
carboxylic acid metabolic process GO:0019752 289 0.024
response to fatty acid GO:0070542 65 0.024
response to nutrient levels GO:0031667 370 0.024
negative regulation of phosphorus metabolic process GO:0010563 80 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
regulation of protein kinase activity GO:0045859 105 0.024
response to cadmium ion GO:0046686 35 0.024
cell cycle process GO:0022402 57 0.024
chromosome separation GO:0051304 1 0.023
negative regulation of cellular protein metabolic process GO:0032269 106 0.023
regulation of protein depolymerization GO:1901879 8 0.023
nucleobase containing compound catabolic process GO:0034655 152 0.023
regulation of rna metabolic process GO:0051252 391 0.023
regulation of histone phosphorylation GO:0033127 3 0.023
embryo development GO:0009790 49 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
cellular component morphogenesis GO:0032989 155 0.023
regulation of mitotic sister chromatid segregation GO:0033047 1 0.022
negative regulation of phosphate metabolic process GO:0045936 80 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
asymmetric protein localization GO:0008105 2 0.022
positive regulation of molecular function GO:0044093 230 0.022
somatic stem cell division GO:0048103 2 0.022
heterocycle catabolic process GO:0046700 167 0.022
ubiquitin dependent protein catabolic process GO:0006511 14 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
muscle structure development GO:0061061 87 0.021
organelle localization GO:0051640 55 0.021
positive regulation of gene expression GO:0010628 244 0.021
intracellular protein transport GO:0006886 79 0.021
neuronal stem cell maintenance GO:0097150 2 0.021
proteolysis GO:0006508 175 0.021
dna conformation change GO:0071103 10 0.021
aging GO:0007568 241 0.021
negative regulation of transcription dna templated GO:0045892 116 0.021
muscle cell differentiation GO:0042692 52 0.021
protein targeting GO:0006605 61 0.021
g1 s transition of mitotic cell cycle GO:0000082 12 0.021
regulation of protein transport GO:0051223 68 0.020
positive regulation of catabolic process GO:0009896 78 0.020
aromatic compound catabolic process GO:0019439 168 0.020
cardiocyte differentiation GO:0035051 22 0.020
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.020
positive regulation of nervous system development GO:0051962 178 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
regulation of striated muscle tissue development GO:0016202 25 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
mrna metabolic process GO:0016071 20 0.020
positive regulation of ligase activity GO:0051351 1 0.020
organophosphate metabolic process GO:0019637 370 0.020
positive regulation of protein metabolic process GO:0051247 178 0.019
response to acid chemical GO:0001101 222 0.019
cellular amine metabolic process GO:0044106 38 0.019
muscle cell proliferation GO:0033002 84 0.019
cellular macromolecule catabolic process GO:0044265 29 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
gamete generation GO:0007276 124 0.019
double strand break repair GO:0006302 1 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
response to ethanol GO:0045471 162 0.019
chromosome localization GO:0050000 1 0.019
single organism cellular localization GO:1902580 102 0.019
regulation of anatomical structure size GO:0090066 135 0.019
cell cell signaling GO:0007267 335 0.018
negative regulation of microtubule polymerization or depolymerization GO:0031111 6 0.018
oxoacid metabolic process GO:0043436 290 0.018
amine metabolic process GO:0009308 38 0.018
dna replication GO:0006260 37 0.018
nucleosome organization GO:0034728 1 0.018
tissue development GO:0009888 252 0.018
cellular modified amino acid biosynthetic process GO:0042398 18 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
microtubule based process GO:0007017 36 0.018
ras protein signal transduction GO:0007265 29 0.018
organelle assembly GO:0070925 22 0.017
cellular response to reactive oxygen species GO:0034614 55 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of nuclear cell cycle dna replication GO:0033262 1 0.017
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.017
regulation of signal transduction GO:0009966 318 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
muscle organ development GO:0007517 50 0.017
male gamete generation GO:0048232 99 0.017
response to axon injury GO:0048678 59 0.017
single organism intracellular transport GO:1902582 166 0.017
positive regulation of cardiac muscle tissue development GO:0055025 9 0.017
regulation of cell morphogenesis GO:0022604 77 0.016
regulation of cytoskeleton organization GO:0051493 49 0.016
transcription dna templated GO:0006351 377 0.016
toxin catabolic process GO:0009407 1 0.016
regulation of synaptic plasticity GO:0048167 70 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
regulation of transcription dna templated GO:0006355 374 0.016
protein maturation GO:0051604 68 0.016
regulation of cardiac muscle tissue growth GO:0055021 12 0.016
regulation of protein localization GO:0032880 81 0.016
regulation of protein modification process GO:0031399 194 0.016
developmental maturation GO:0021700 25 0.016
protein localization to organelle GO:0033365 57 0.016
positive regulation of growth GO:0045927 55 0.016
rna biosynthetic process GO:0032774 380 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
centrosome cycle GO:0007098 1 0.016
cellular protein complex assembly GO:0043623 44 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
cellular protein catabolic process GO:0044257 19 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
metaphase anaphase transition of cell cycle GO:0044784 1 0.015
heart development GO:0007507 72 0.015
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
establishment of chromosome localization GO:0051303 1 0.015
tube development GO:0035295 89 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
protein localization to chromosome GO:0034502 1 0.015
heart growth GO:0060419 20 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
dna integrity checkpoint GO:0031570 2 0.014
regulation of organ growth GO:0046620 13 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
negative regulation of phosphorylation GO:0042326 57 0.014
regulation of ligase activity GO:0051340 3 0.014
single organism biosynthetic process GO:0044711 342 0.014
spermatogenesis GO:0007283 99 0.014
single organism membrane organization GO:0044802 74 0.014
organ growth GO:0035265 24 0.014
negative regulation of nuclear division GO:0051784 1 0.014
positive regulation of organelle organization GO:0010638 48 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
organophosphate catabolic process GO:0046434 148 0.014
regulation of protein maturation GO:1903317 50 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
mitotic cell cycle process GO:1903047 35 0.013
regulation of synaptic transmission GO:0050804 141 0.013
chromatin assembly or disassembly GO:0006333 1 0.013
organelle fission GO:0048285 25 0.013
response to oxidative stress GO:0006979 186 0.013
protein processing GO:0016485 68 0.013
anterior posterior pattern specification GO:0009952 1 0.013
dephosphorylation GO:0016311 98 0.013
axis specification GO:0009798 4 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
mitotic cell cycle GO:0000278 49 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
intracellular transport GO:0046907 185 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.012
negative regulation of protein phosphorylation GO:0001933 44 0.012
maintenance of protein location GO:0045185 7 0.012
negative regulation of cell communication GO:0010648 158 0.012
positive regulation of signaling GO:0023056 270 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
protein import into nucleus GO:0006606 35 0.012
microtubule organizing center organization GO:0031023 1 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
response to extracellular stimulus GO:0009991 380 0.012
protein transport GO:0015031 132 0.012
regulation of dendrite development GO:0050773 59 0.012
cardiac muscle tissue development GO:0048738 26 0.012
regulation of cell cycle process GO:0010564 31 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
response to glucocorticoid GO:0051384 223 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
negative regulation of molecular function GO:0044092 133 0.011
cellular response to hypoxia GO:0071456 51 0.011
hepaticobiliary system development GO:0061008 90 0.011
covalent chromatin modification GO:0016569 30 0.011
single organism nuclear import GO:1902593 35 0.011
regulation of dna metabolic process GO:0051052 60 0.011
mitotic dna damage checkpoint GO:0044773 1 0.011
regulation of chromatin binding GO:0035561 3 0.011
maintenance of protein location in cell GO:0032507 7 0.011
nucleoside metabolic process GO:0009116 179 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
response to corticosteroid GO:0031960 235 0.011
cellular response to iron ion GO:0071281 5 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
actin filament based process GO:0030029 86 0.011
negative regulation of cell division GO:0051782 1 0.011
single fertilization GO:0007338 3 0.011
cerebellar purkinje cell layer formation GO:0021694 1 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
digestive tract development GO:0048565 39 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
mitotic cell cycle checkpoint GO:0007093 1 0.010
mrna 3 end processing GO:0031124 1 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
cellular response to metal ion GO:0071248 55 0.010
negative regulation of signaling GO:0023057 157 0.010
brain development GO:0007420 247 0.010
muscle cell development GO:0055001 26 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
central nervous system development GO:0007417 311 0.010
negative regulation of neuron differentiation GO:0045665 62 0.010
lipid metabolic process GO:0006629 283 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010

Pttg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org