Rattus norvegicus

0 known processes

Pum1

pumilio homolog 1 (Drosophila)

Pum1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 181 0.279
transcription dna templated GO:0006351 377 0.245
rna metabolic process GO:0016070 406 0.237
regulation of nucleic acid templated transcription GO:1903506 380 0.181
nucleoside triphosphate catabolic process GO:0009143 123 0.175
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.160
endocytosis GO:0006897 84 0.151
purine nucleotide catabolic process GO:0006195 136 0.146
purine nucleoside triphosphate catabolic process GO:0009146 122 0.141
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.138
regulation of phosphorus metabolic process GO:0051174 349 0.136
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.134
negative regulation of cellular biosynthetic process GO:0031327 161 0.133
organelle organization GO:0006996 266 0.128
regulation of transcription dna templated GO:0006355 374 0.126
carbohydrate derivative catabolic process GO:1901136 147 0.126
purine ribonucleotide catabolic process GO:0009154 136 0.122
ribonucleoside triphosphate catabolic process GO:0009203 122 0.119
ribonucleoside triphosphate metabolic process GO:0009199 141 0.117
nucleoside triphosphate metabolic process GO:0009141 144 0.115
ribonucleoside catabolic process GO:0042454 126 0.114
organophosphate metabolic process GO:0019637 370 0.110
cellular catabolic process GO:0044248 295 0.104
gtp metabolic process GO:0046039 72 0.102
positive regulation of phosphate metabolic process GO:0045937 262 0.102
purine containing compound catabolic process GO:0072523 138 0.100
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.100
nucleoside phosphate metabolic process GO:0006753 283 0.097
negative regulation of cellular metabolic process GO:0031324 281 0.097
organonitrogen compound catabolic process GO:1901565 179 0.097
positive regulation of molecular function GO:0044093 230 0.095
aromatic compound catabolic process GO:0019439 168 0.092
negative regulation of apoptotic process GO:0043066 181 0.092
purine containing compound metabolic process GO:0072521 253 0.090
ribonucleotide catabolic process GO:0009261 136 0.090
purine ribonucleoside catabolic process GO:0046130 124 0.090
single organism organelle organization GO:1902589 180 0.090
guanosine containing compound metabolic process GO:1901068 74 0.088
organic substance catabolic process GO:1901575 316 0.085
brain development GO:0007420 247 0.084
catabolic process GO:0009056 351 0.084
ribonucleotide metabolic process GO:0009259 231 0.083
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.082
ribose phosphate metabolic process GO:0019693 235 0.081
purine nucleoside catabolic process GO:0006152 124 0.079
purine nucleotide metabolic process GO:0006163 229 0.078
nucleotide metabolic process GO:0009117 279 0.077
intracellular signal transduction GO:0035556 314 0.076
nucleoside phosphate catabolic process GO:1901292 140 0.075
glycosyl compound metabolic process GO:1901657 182 0.075
purine nucleoside metabolic process GO:0042278 169 0.075
ribonucleoside metabolic process GO:0009119 174 0.074
positive regulation of phosphorus metabolic process GO:0010562 262 0.074
purine ribonucleotide metabolic process GO:0009150 227 0.071
regulation of purine nucleotide catabolic process GO:0033121 65 0.070
nucleic acid templated transcription GO:0097659 379 0.070
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.068
gtp catabolic process GO:0006184 71 0.067
regulation of protein metabolic process GO:0051246 289 0.066
carbohydrate derivative metabolic process GO:1901135 346 0.066
regulation of catalytic activity GO:0050790 304 0.066
nucleobase containing compound catabolic process GO:0034655 152 0.066
organic cyclic compound catabolic process GO:1901361 175 0.065
positive regulation of nucleotide catabolic process GO:0030813 53 0.065
heterocycle catabolic process GO:0046700 167 0.065
regulation of nucleotide catabolic process GO:0030811 65 0.064
purine nucleoside triphosphate metabolic process GO:0009144 141 0.064
regulation of nucleotide metabolic process GO:0006140 117 0.064
response to fungicide GO:0060992 20 0.064
negative regulation of biosynthetic process GO:0009890 168 0.063
central nervous system development GO:0007417 311 0.062
regulation of rna biosynthetic process GO:2001141 381 0.061
single organism catabolic process GO:0044712 283 0.061
rna biosynthetic process GO:0032774 380 0.061
cellular response to growth factor stimulus GO:0071363 162 0.061
regulation of hydrolase activity GO:0051336 143 0.059
macromolecular complex subunit organization GO:0043933 339 0.058
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.058
regulation of molecular function GO:0065009 398 0.058
regulation of cellular protein metabolic process GO:0032268 267 0.058
positive regulation of nucleotide metabolic process GO:0045981 91 0.057
nucleoside metabolic process GO:0009116 179 0.056
guanosine containing compound catabolic process GO:1901069 71 0.056
ras protein signal transduction GO:0007265 29 0.056
cellular component biogenesis GO:0044085 368 0.055
glycosyl compound catabolic process GO:1901658 126 0.055
negative regulation of gene expression GO:0010629 199 0.055
negative regulation of nucleic acid templated transcription GO:1903507 117 0.054
regulation of purine nucleotide metabolic process GO:1900542 115 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.052
regulation of cellular component organization GO:0051128 368 0.052
response to other organism GO:0051707 220 0.052
nucleotide catabolic process GO:0009166 139 0.052
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.051
cellular nitrogen compound catabolic process GO:0044270 163 0.050
carboxylic acid metabolic process GO:0019752 289 0.050
regulation of apoptotic process GO:0042981 335 0.049
positive regulation of catalytic activity GO:0043085 184 0.049
head development GO:0060322 247 0.048
regulation of phosphate metabolic process GO:0019220 349 0.046
small gtpase mediated signal transduction GO:0007264 36 0.046
positive regulation of cell differentiation GO:0045597 217 0.046
apoptotic process GO:0006915 381 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.045
defense response GO:0006952 194 0.045
secretion GO:0046903 307 0.044
positive regulation of cellular biosynthetic process GO:0031328 295 0.044
enzyme linked receptor protein signaling pathway GO:0007167 116 0.044
homeostatic process GO:0042592 331 0.042
positive regulation of rna biosynthetic process GO:1902680 197 0.042
response to fibroblast growth factor GO:0071774 29 0.041
locomotion GO:0040011 237 0.041
positive regulation of multicellular organismal process GO:0051240 387 0.041
response to growth factor GO:0070848 189 0.041
positive regulation of nucleoside metabolic process GO:0045979 55 0.041
single organism reproductive process GO:0044702 297 0.041
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.039
tissue development GO:0009888 252 0.039
cellular response to endogenous stimulus GO:0071495 377 0.039
negative regulation of metabolic process GO:0009892 331 0.039
positive regulation of developmental process GO:0051094 283 0.039
neuron projection development GO:0031175 273 0.039
regulation of multicellular organismal development GO:2000026 376 0.038
cellular component movement GO:0006928 248 0.038
regulation of programmed cell death GO:0043067 341 0.038
positive regulation of hydrolase activity GO:0051345 86 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
macromolecule localization GO:0033036 252 0.037
neuron differentiation GO:0030182 368 0.036
organic acid metabolic process GO:0006082 292 0.036
programmed cell death GO:0012501 392 0.035
regulation of signal transduction GO:0009966 318 0.035
negative regulation of rna metabolic process GO:0051253 123 0.035
cellular amino acid metabolic process GO:0006520 107 0.035
localization of cell GO:0051674 202 0.034
oxoacid metabolic process GO:0043436 290 0.034
positive regulation of cellular catabolic process GO:0031331 71 0.034
regulation of nucleoside metabolic process GO:0009118 66 0.033
regulation of cell migration GO:0030334 128 0.032
anterior posterior pattern specification GO:0009952 1 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.032
cellular component assembly GO:0022607 360 0.032
regulation of rna metabolic process GO:0051252 391 0.031
negative regulation of programmed cell death GO:0043069 183 0.031
reproductive process GO:0022414 372 0.030
transcription from rna polymerase ii promoter GO:0006366 252 0.030
purine ribonucleoside metabolic process GO:0046128 168 0.030
negative regulation of transcription dna templated GO:0045892 116 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
response to extracellular stimulus GO:0009991 380 0.028
negative regulation of cell death GO:0060548 229 0.028
peptidyl amino acid modification GO:0018193 126 0.028
ribonucleoside monophosphate metabolic process GO:0009161 88 0.028
cellular cation homeostasis GO:0030003 180 0.027
reproduction GO:0000003 245 0.027
amine metabolic process GO:0009308 38 0.027
regulation of bmp signaling pathway GO:0030510 2 0.027
positive regulation of catabolic process GO:0009896 78 0.027
response to nutrient levels GO:0031667 370 0.026
nucleoside monophosphate metabolic process GO:0009123 93 0.026
organophosphate catabolic process GO:0046434 148 0.026
response to external biotic stimulus GO:0043207 221 0.026
protein complex biogenesis GO:0070271 263 0.025
negative regulation of rna biosynthetic process GO:1902679 118 0.025
purine nucleoside monophosphate metabolic process GO:0009126 84 0.025
nucleoside catabolic process GO:0009164 126 0.025
cell motility GO:0048870 202 0.025
cellular amine metabolic process GO:0044106 38 0.024
cell projection organization GO:0030030 302 0.024
biological adhesion GO:0022610 110 0.024
ion homeostasis GO:0050801 212 0.023
regulation of cellular catabolic process GO:0031329 101 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
nucleoside monophosphate catabolic process GO:0009125 56 0.023
dna metabolic process GO:0006259 96 0.023
regulation of cell development GO:0060284 263 0.022
histone h3 k9 methylation GO:0051567 1 0.022
cell adhesion GO:0007155 110 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
cellular chemical homeostasis GO:0055082 247 0.022
protein phosphorylation GO:0006468 345 0.022
cellular ion homeostasis GO:0006873 184 0.022
cell migration GO:0016477 197 0.022
regulation of body fluid levels GO:0050878 90 0.022
intracellular transport GO:0046907 185 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
regulation of protein modification process GO:0031399 194 0.021
regulation of phosphorylation GO:0042325 248 0.021
chromatin organization GO:0006325 34 0.021
developmental process involved in reproduction GO:0003006 159 0.021
positive regulation of cell communication GO:0010647 271 0.021
development of primary sexual characteristics GO:0045137 107 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
neuron projection morphogenesis GO:0048812 122 0.021
multicellular organism reproduction GO:0032504 233 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
asymmetric protein localization GO:0008105 2 0.021
regulation of cell differentiation GO:0045595 320 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.020
cellular response to lipid GO:0071396 201 0.020
atp metabolic process GO:0046034 72 0.020
single organism intracellular transport GO:1902582 166 0.020
atp catabolic process GO:0006200 54 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
dna methylation or demethylation GO:0044728 8 0.020
purine nucleoside monophosphate catabolic process GO:0009128 55 0.020
axis specification GO:0009798 4 0.020
regulation of protein localization GO:0032880 81 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
positive regulation of gene expression GO:0010628 244 0.019
neurological system process GO:0050877 219 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
cellular ketone metabolic process GO:0042180 51 0.019
ribonucleoside monophosphate catabolic process GO:0009158 55 0.018
response to bacterium GO:0009617 200 0.018
regulation of catabolic process GO:0009894 113 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
positive regulation of nervous system development GO:0051962 178 0.018
negative regulation of molecular function GO:0044092 133 0.018
cytoplasmic transport GO:0016482 115 0.018
negative regulation of developmental process GO:0051093 125 0.018
multicellular organismal reproductive process GO:0048609 233 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
positive regulation of signaling GO:0023056 270 0.017
reproductive system development GO:0061458 128 0.017
vasculogenesis GO:0001570 3 0.017
cation homeostasis GO:0055080 195 0.017
sexual reproduction GO:0019953 148 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of anatomical structure size GO:0090066 135 0.017
positive regulation of cell development GO:0010720 176 0.017
behavior GO:0007610 205 0.017
regulation of gtpase activity GO:0043087 57 0.016
response to biotic stimulus GO:0009607 226 0.016
aging GO:0007568 241 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
body fluid secretion GO:0007589 41 0.016
cell part morphogenesis GO:0032990 123 0.016
circulatory system process GO:0003013 183 0.016
regulation of cellular component movement GO:0051270 150 0.016
rab protein signal transduction GO:0032482 1 0.016
cell type specific apoptotic process GO:0097285 134 0.016
actin filament based process GO:0030029 86 0.016
regulation of cell projection organization GO:0031344 175 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
positive regulation of signal transduction GO:0009967 175 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
immune system process GO:0002376 204 0.015
cardiovascular system development GO:0072358 134 0.015
transmembrane transport GO:0055085 412 0.015
chemical homeostasis GO:0048878 292 0.015
cell morphogenesis GO:0000902 142 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
regulation of cell adhesion GO:0030155 52 0.015
macromolecular complex assembly GO:0065003 273 0.015
gamete generation GO:0007276 124 0.015
regulation of system process GO:0044057 208 0.014
growth GO:0040007 165 0.014
neuron death GO:0070997 127 0.014
regulation of nervous system development GO:0051960 264 0.014
regulation of organelle organization GO:0033043 80 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.014
embryo development GO:0009790 49 0.014
regulation of cell proliferation GO:0042127 359 0.014
cell matrix adhesion GO:0007160 19 0.014
heart morphogenesis GO:0003007 3 0.014
single organism biosynthetic process GO:0044711 342 0.014
regulation of gtp catabolic process GO:0033124 58 0.014
circulatory system development GO:0072359 134 0.014
mechanoreceptor differentiation GO:0042490 2 0.014
gonad development GO:0008406 104 0.014
protein complex assembly GO:0006461 263 0.014
positive regulation of atpase activity GO:0032781 6 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
neuron development GO:0048666 286 0.014
response to ethanol GO:0045471 162 0.014
regulation of locomotion GO:0040012 148 0.014
single organism membrane organization GO:0044802 74 0.013
positive regulation of gtp catabolic process GO:0033126 48 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
sex differentiation GO:0007548 113 0.013
positive regulation of gtpase activity GO:0043547 47 0.013
protein deubiquitination GO:0016579 4 0.013
gastrulation GO:0007369 2 0.013
chromatin modification GO:0016568 33 0.013
eye morphogenesis GO:0048592 4 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
cell substrate adhesion GO:0031589 29 0.013
response to oxygen levels GO:0070482 265 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
motor neuron axon guidance GO:0008045 1 0.013
regulation of immune system process GO:0002682 123 0.012
cellular component morphogenesis GO:0032989 155 0.012
bmp signaling pathway GO:0030509 4 0.012
calcium ion homeostasis GO:0055074 162 0.012
male gamete generation GO:0048232 99 0.012
histone methylation GO:0016571 3 0.012
single organism behavior GO:0044708 130 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of atpase activity GO:0043462 7 0.012
neural crest cell differentiation GO:0014033 2 0.012
cellular response to stress GO:0033554 269 0.012
cation transport GO:0006812 382 0.012
response to decreased oxygen levels GO:0036293 237 0.012
chromosome organization GO:0051276 36 0.012
muscle system process GO:0003012 115 0.012
multi organism reproductive process GO:0044703 262 0.011
regulation of actin filament based process GO:0032970 42 0.011
muscle structure development GO:0061061 87 0.011
regulation of ras gtpase activity GO:0032318 32 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
ncrna processing GO:0034470 3 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
positive regulation of ras gtpase activity GO:0032320 28 0.011
carbohydrate metabolic process GO:0005975 130 0.011
regulation of secretion GO:0051046 224 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
regulation of transferase activity GO:0051338 123 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
response to acid chemical GO:0001101 222 0.011
response to hypoxia GO:0001666 231 0.011
positive regulation of transport GO:0051050 245 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of neurogenesis GO:0050767 247 0.010
olfactory learning GO:0008355 1 0.010
regulation of growth GO:0040008 105 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
non canonical wnt signaling pathway GO:0035567 3 0.010
negative regulation of cell communication GO:0010648 158 0.010
membrane organization GO:0061024 94 0.010
response to hexose GO:0009746 144 0.010
dephosphorylation GO:0016311 98 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
rhythmic process GO:0048511 156 0.010
response to wounding GO:0009611 254 0.010
erythrocyte differentiation GO:0030218 1 0.010

Pum1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
colon carcinoma DOID:1520 0 0.011
large intestine cancer DOID:5672 0 0.011
colon cancer DOID:219 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
colorectal cancer DOID:9256 0 0.011