Rattus norvegicus

0 known processes

Pxdn

peroxidasin homolog (Drosophila)

(Aliases: Perc64)

Pxdn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of axon guidance GO:1902669 3 0.530
regulation of multicellular organismal development GO:2000026 376 0.313
negative regulation of cell development GO:0010721 82 0.269
response to growth factor GO:0070848 189 0.225
regulation of signal transduction GO:0009966 318 0.185
growth GO:0040007 165 0.182
positive regulation of phosphate metabolic process GO:0045937 262 0.181
positive regulation of axon extension involved in axon guidance GO:0048842 3 0.157
cellular response to endogenous stimulus GO:0071495 377 0.155
regulation of neurogenesis GO:0050767 247 0.148
blood vessel morphogenesis GO:0048514 58 0.143
regulation of cell development GO:0060284 263 0.140
tissue development GO:0009888 252 0.131
regulation of neuron differentiation GO:0045664 208 0.131
axon extension involved in axon guidance GO:0048846 6 0.130
response to radiation GO:0009314 137 0.125
neuron apoptotic process GO:0051402 88 0.121
cell type specific apoptotic process GO:0097285 134 0.111
positive regulation of signal transduction GO:0009967 175 0.109
regulation of cellular component organization GO:0051128 368 0.107
motor neuron axon guidance GO:0008045 1 0.106
aorta development GO:0035904 2 0.106
cell chemotaxis GO:0060326 31 0.105
regulation of neuron death GO:1901214 115 0.097
regulation of cellular component movement GO:0051270 150 0.097
anatomical structure formation involved in morphogenesis GO:0048646 83 0.093
coronary vasculature morphogenesis GO:0060977 3 0.092
neuron death GO:0070997 127 0.090
regulation of nervous system development GO:0051960 264 0.090
regulation of cell differentiation GO:0045595 320 0.090
cellular response to growth factor stimulus GO:0071363 162 0.088
bone development GO:0060348 25 0.085
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.085
positive regulation of signaling GO:0023056 270 0.082
negative regulation of multicellular organismal process GO:0051241 203 0.081
positive regulation of phosphorus metabolic process GO:0010562 262 0.080
positive regulation of cell communication GO:0010647 271 0.080
cellular component movement GO:0006928 248 0.079
transcription dna templated GO:0006351 377 0.078
response to ionizing radiation GO:0010212 59 0.076
response to estrogen GO:0043627 232 0.075
locomotion GO:0040011 237 0.075
response to estradiol GO:0032355 164 0.073
regulation of phosphate metabolic process GO:0019220 349 0.071
positive regulation of cell differentiation GO:0045597 217 0.069
cardiovascular system development GO:0072358 134 0.068
vasculature development GO:0001944 70 0.068
negative regulation of axon guidance GO:1902668 3 0.066
vascular endothelial growth factor receptor signaling pathway GO:0048010 8 0.066
regulation of rna biosynthetic process GO:2001141 381 0.066
developmental growth involved in morphogenesis GO:0060560 33 0.066
regulation of neuron apoptotic process GO:0043523 83 0.064
neural crest cell development GO:0014032 2 0.064
response to peptide hormone GO:0043434 278 0.063
regulation of transcription dna templated GO:0006355 374 0.062
tooth eruption GO:0044691 1 0.061
protein localization GO:0008104 191 0.060
cell motility GO:0048870 202 0.060
parasympathetic nervous system development GO:0048486 1 0.059
neuron differentiation GO:0030182 368 0.058
regulation of locomotion GO:0040012 148 0.057
cellular amino acid metabolic process GO:0006520 107 0.056
regulation of nucleic acid templated transcription GO:1903506 380 0.056
positive regulation of locomotion GO:0040017 102 0.055
positive regulation of transcription dna templated GO:0045893 197 0.054
anatomical structure morphogenesis GO:0009653 298 0.053
positive regulation of protein metabolic process GO:0051247 178 0.052
response to nutrient levels GO:0031667 370 0.052
negative regulation of chemotaxis GO:0050922 5 0.052
positive regulation of developmental process GO:0051094 283 0.051
angiogenesis GO:0001525 53 0.051
regulation of axonogenesis GO:0050770 37 0.051
substrate dependent cerebral cortex tangential migration GO:0021825 1 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.050
regulation of cell projection organization GO:0031344 175 0.049
oxoacid metabolic process GO:0043436 290 0.048
rna biosynthetic process GO:0032774 380 0.048
cellular ketone metabolic process GO:0042180 51 0.048
cellular amine metabolic process GO:0044106 38 0.046
cellular response to peptide GO:1901653 133 0.046
negative regulation of developmental process GO:0051093 125 0.046
negative regulation of response to stimulus GO:0048585 155 0.046
regulation of neuron projection development GO:0010975 161 0.046
carboxylic acid metabolic process GO:0019752 289 0.045
organic acid metabolic process GO:0006082 292 0.044
developmental growth GO:0048589 100 0.044
blood vessel development GO:0001568 69 0.044
cellular calcium ion homeostasis GO:0006874 160 0.043
cellular response to organic cyclic compound GO:0071407 202 0.043
positive regulation of rna biosynthetic process GO:1902680 197 0.042
positive regulation of phosphorylation GO:0042327 177 0.042
amine metabolic process GO:0009308 38 0.042
negative regulation of neurogenesis GO:0050768 78 0.042
negative regulation of signaling GO:0023057 157 0.041
single organism biosynthetic process GO:0044711 342 0.041
negative regulation of cell differentiation GO:0045596 99 0.041
positive regulation of response to stimulus GO:0048584 285 0.041
positive regulation of multicellular organismal process GO:0051240 387 0.040
response to oxidative stress GO:0006979 186 0.040
regulation of protein modification process GO:0031399 194 0.040
localization of cell GO:0051674 202 0.040
positive regulation of rna metabolic process GO:0051254 203 0.040
negative regulation of neuron death GO:1901215 69 0.040
regulation of phosphorus metabolic process GO:0051174 349 0.040
retinal ganglion cell axon guidance GO:0031290 1 0.040
negative regulation of neuron apoptotic process GO:0043524 45 0.039
regulation of anatomical structure morphogenesis GO:0022603 141 0.039
nucleic acid templated transcription GO:0097659 379 0.039
neuron development GO:0048666 286 0.039
response to mechanical stimulus GO:0009612 134 0.039
neural crest cell migration GO:0001755 1 0.038
intracellular signal transduction GO:0035556 314 0.038
cell migration GO:0016477 197 0.037
regulation of growth GO:0040008 105 0.036
regulation of intracellular signal transduction GO:1902531 218 0.036
toxin transport GO:1901998 3 0.036
positive regulation of cellular amine metabolic process GO:0033240 3 0.036
positive regulation of intracellular signal transduction GO:1902533 138 0.036
hepatocyte growth factor receptor signaling pathway GO:0048012 1 0.035
endochondral bone morphogenesis GO:0060350 7 0.035
cellular response to abiotic stimulus GO:0071214 85 0.035
regulation of rna metabolic process GO:0051252 391 0.034
cellular response to organonitrogen compound GO:0071417 197 0.034
apoptotic process GO:0006915 381 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.034
neuron projection development GO:0031175 273 0.033
forebrain development GO:0030900 98 0.033
brain development GO:0007420 247 0.033
apoptotic signaling pathway GO:0097190 27 0.033
connective tissue development GO:0061448 33 0.033
cellular ion homeostasis GO:0006873 184 0.033
organelle organization GO:0006996 266 0.032
regulation of protein metabolic process GO:0051246 289 0.032
circulatory system development GO:0072359 134 0.031
regulation of axon extension GO:0030516 24 0.031
response to extracellular stimulus GO:0009991 380 0.031
neuron projection guidance GO:0097485 24 0.031
muscle structure development GO:0061061 87 0.030
organonitrogen compound biosynthetic process GO:1901566 167 0.030
carbohydrate derivative biosynthetic process GO:1901137 124 0.030
response to fluoride GO:1902617 3 0.030
salivary gland development GO:0007431 3 0.030
cell growth GO:0016049 104 0.030
response to peptide GO:1901652 292 0.030
response to acid chemical GO:0001101 222 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
cell adhesion GO:0007155 110 0.029
enzyme linked receptor protein signaling pathway GO:0007167 116 0.029
regulation of phosphorylation GO:0042325 248 0.029
cellular cation homeostasis GO:0030003 180 0.029
macromolecule localization GO:0033036 252 0.029
chemotaxis GO:0006935 66 0.029
positive regulation of cellular component organization GO:0051130 200 0.029
positive regulation of cellular component movement GO:0051272 102 0.028
regulation of cellular localization GO:0060341 263 0.028
response to tumor necrosis factor GO:0034612 56 0.028
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.027
erk1 and erk2 cascade GO:0070371 48 0.027
positive regulation of neurogenesis GO:0050769 165 0.027
cellular response to peptide hormone stimulus GO:0071375 120 0.027
regulation of protein phosphorylation GO:0001932 183 0.027
cellular macromolecule localization GO:0070727 122 0.027
regulation of molecular function GO:0065009 398 0.026
cell morphogenesis involved in differentiation GO:0000904 119 0.026
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.026
cell projection morphogenesis GO:0048858 123 0.026
negative regulation of nervous system development GO:0051961 79 0.026
response to wounding GO:0009611 254 0.026
cytosolic calcium ion homeostasis GO:0051480 140 0.025
negative regulation of signal transduction GO:0009968 83 0.025
negative regulation of phosphate metabolic process GO:0045936 80 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
extracellular structure organization GO:0043062 13 0.025
response to nutrient GO:0007584 248 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
mapk cascade GO:0000165 140 0.024
cellular response to lipid GO:0071396 201 0.024
regulation of apoptotic process GO:0042981 335 0.024
regulation of immune system process GO:0002682 123 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
positive regulation of nervous system development GO:0051962 178 0.023
renal system development GO:0072001 67 0.023
regulation of canonical wnt signaling pathway GO:0060828 4 0.023
sex differentiation GO:0007548 113 0.023
salivary gland morphogenesis GO:0007435 1 0.023
positive regulation of mapk cascade GO:0043410 92 0.023
regeneration GO:0031099 163 0.023
positive regulation of cell development GO:0010720 176 0.022
autonomic nervous system development GO:0048483 3 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.022
metal ion homeostasis GO:0055065 186 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
regulation of catalytic activity GO:0050790 304 0.021
response to corticosteroid GO:0031960 235 0.021
negative regulation of neuron projection development GO:0010977 46 0.021
ion homeostasis GO:0050801 212 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
response to vitamin GO:0033273 131 0.021
cerebral cortex tangential migration GO:0021800 1 0.021
positive regulation of biosynthetic process GO:0009891 319 0.020
kidney development GO:0001822 67 0.020
transmembrane transport GO:0055085 412 0.020
head development GO:0060322 247 0.020
cell projection organization GO:0030030 302 0.020
gland development GO:0048732 155 0.020
protein phosphorylation GO:0006468 345 0.020
inner ear morphogenesis GO:0042472 1 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
cell cell signaling GO:0007267 335 0.020
response to cytokine GO:0034097 215 0.020
forebrain neuron development GO:0021884 3 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
regulation of cell morphogenesis GO:0022604 77 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
regulation of epithelial cell proliferation GO:0050678 49 0.019
positive regulation of gene expression GO:0010628 244 0.019
cerebral cortex cell migration GO:0021795 4 0.019
development of primary sexual characteristics GO:0045137 107 0.019
response to oxygen levels GO:0070482 265 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
positive regulation of axon extension GO:0045773 14 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
ras protein signal transduction GO:0007265 29 0.018
positive regulation of growth GO:0045927 55 0.018
neuron migration GO:0001764 21 0.018
organ regeneration GO:0031100 101 0.018
urogenital system development GO:0001655 78 0.018
regulation of behavior GO:0050795 61 0.018
gonad development GO:0008406 104 0.018
response to vitamin e GO:0033197 24 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
chemical homeostasis GO:0048878 292 0.018
cellular response to vascular endothelial growth factor stimulus GO:0035924 6 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
cellular protein localization GO:0034613 122 0.018
cell morphogenesis GO:0000902 142 0.018
ion transmembrane transport GO:0034220 365 0.017
establishment of protein localization GO:0045184 141 0.017
regulation of programmed cell death GO:0043067 341 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
negative regulation of cell projection organization GO:0031345 50 0.017
kidney vasculature development GO:0061440 6 0.017
axis specification GO:0009798 4 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.017
regulation of stem cell differentiation GO:2000736 2 0.017
negative regulation of cell communication GO:0010648 158 0.017
skeletal system development GO:0001501 41 0.017
positive regulation of cell migration GO:0030335 96 0.017
multicellular organism reproduction GO:0032504 233 0.017
regulation of anatomical structure size GO:0090066 135 0.016
response to alkaloid GO:0043279 132 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
vesicle mediated transport GO:0016192 181 0.016
homeostatic process GO:0042592 331 0.016
forebrain generation of neurons GO:0021872 8 0.016
formation of primary germ layer GO:0001704 1 0.016
eye morphogenesis GO:0048592 4 0.016
dendrite development GO:0016358 72 0.016
sensory organ development GO:0007423 74 0.016
embryonic pattern specification GO:0009880 1 0.016
negative regulation of cell growth GO:0030308 33 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
nucleotide metabolic process GO:0009117 279 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
sequestering of metal ion GO:0051238 9 0.015
reproductive process GO:0022414 372 0.015
peptidyl tyrosine modification GO:0018212 72 0.015
cellular homeostasis GO:0019725 252 0.015
epithelial cell migration GO:0010631 19 0.015
multi organism reproductive process GO:0044703 262 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
artery development GO:0060840 3 0.015
regulation of transferase activity GO:0051338 123 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.015
organophosphate metabolic process GO:0019637 370 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
single organism membrane organization GO:0044802 74 0.015
cell part morphogenesis GO:0032990 123 0.015
axon extension GO:0048675 26 0.014
response to inorganic substance GO:0010035 377 0.014
ribose phosphate biosynthetic process GO:0046390 87 0.014
regulation of kinase activity GO:0043549 117 0.014
negative regulation of gene expression GO:0010629 199 0.014
programmed cell death GO:0012501 392 0.014
regulation of cell migration GO:0030334 128 0.014
aging GO:0007568 241 0.014
regulation of chemotaxis GO:0050920 29 0.014
substrate dependent cell migration GO:0006929 1 0.014
positive regulation of protein modification process GO:0031401 142 0.014
tube development GO:0035295 89 0.014
response to transforming growth factor beta GO:0071559 46 0.014
regulation of fat cell differentiation GO:0045598 3 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
rna metabolic process GO:0016070 406 0.014
extracellular fibril organization GO:0043206 1 0.014
regulation of developmental growth GO:0048638 45 0.014
regulation of system process GO:0044057 208 0.013
cellular response to external stimulus GO:0071496 118 0.013
response to reactive oxygen species GO:0000302 120 0.013
regulation of vesicle mediated transport GO:0060627 81 0.013
negative regulation of metabolic process GO:0009892 331 0.013
positive regulation of neuron death GO:1901216 43 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
positive regulation of angiogenesis GO:0045766 28 0.013
neuron projection morphogenesis GO:0048812 122 0.013
hypothalamus development GO:0021854 11 0.013
female pregnancy GO:0007565 122 0.013
antigen receptor mediated signaling pathway GO:0050851 1 0.013
neuron projection extension GO:1990138 26 0.013
neuronal stem cell maintenance GO:0097150 2 0.013
positive regulation of kinase activity GO:0033674 77 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
negative regulation of axon extension involved in axon guidance GO:0048843 3 0.013
reproduction GO:0000003 245 0.012
male gonad development GO:0008584 59 0.012
negative regulation of immune system process GO:0002683 39 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
cellular response to stress GO:0033554 269 0.012
cellular component biogenesis GO:0044085 368 0.012
sexual reproduction GO:0019953 148 0.012
telencephalon development GO:0021537 62 0.012
cation transport GO:0006812 382 0.012
gastrulation GO:0007369 2 0.012
calcium ion homeostasis GO:0055074 162 0.012
positive regulation of transport GO:0051050 245 0.012
aminoglycan biosynthetic process GO:0006023 4 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
response to calcium ion GO:0051592 59 0.012
multicellular organism growth GO:0035264 1 0.012
female sex differentiation GO:0046660 59 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
glycosaminoglycan biosynthetic process GO:0006024 4 0.012
diencephalon development GO:0021536 21 0.012
immune system process GO:0002376 204 0.012
cellular response to oxygen containing compound GO:1901701 386 0.012
response to metal ion GO:0010038 253 0.012
regulation of embryonic development GO:0045995 2 0.012
ventricular cardiac muscle cell action potential GO:0086005 2 0.012
protein complex subunit organization GO:0071822 302 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
nucleoside metabolic process GO:0009116 179 0.012
cation homeostasis GO:0055080 195 0.012
sympathetic nervous system development GO:0048485 1 0.012
sulfation GO:0051923 2 0.012
ribose phosphate metabolic process GO:0019693 235 0.011
regulation of cell growth GO:0001558 85 0.011
limbic system development GO:0021761 38 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
growth plate cartilage development GO:0003417 2 0.011
asymmetric stem cell division GO:0098722 2 0.011
bone morphogenesis GO:0060349 11 0.011
positive regulation of molecular function GO:0044093 230 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
innervation GO:0060384 1 0.011
heart development GO:0007507 72 0.011
developmental process involved in reproduction GO:0003006 159 0.011
regulation of protein kinase activity GO:0045859 105 0.011
positive regulation of stem cell differentiation GO:2000738 2 0.011
cartilage development involved in endochondral bone morphogenesis GO:0060351 3 0.011
regulation of mapk cascade GO:0043408 116 0.011
spermatogenesis GO:0007283 99 0.011
cellular response to ketone GO:1901655 51 0.011
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
axonogenesis GO:0007409 71 0.011
regulation of cell motility GO:2000145 131 0.011
response to decreased oxygen levels GO:0036293 237 0.011
pinocytosis GO:0006907 1 0.011
taxis GO:0042330 67 0.011
mesenchymal cell differentiation GO:0048762 8 0.011
response to gamma radiation GO:0010332 24 0.011
negative regulation of molecular function GO:0044092 133 0.011
male gamete generation GO:0048232 99 0.011
receptor metabolic process GO:0043112 18 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
single organism reproductive process GO:0044702 297 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
regulation of epithelial to mesenchymal transition GO:0010717 2 0.010
cellular response to tumor necrosis factor GO:0071356 46 0.010
regulation of secretion by cell GO:1903530 208 0.010
response to toxic substance GO:0009636 133 0.010
sulfur compound metabolic process GO:0006790 70 0.010
embryonic skeletal system development GO:0048706 3 0.010
organ morphogenesis GO:0009887 75 0.010
cellular response to retinoic acid GO:0071300 27 0.010
rho protein signal transduction GO:0007266 11 0.010
actin filament based movement GO:0030048 16 0.010
positive regulation of fatty acid beta oxidation GO:0032000 4 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
synaptic transmission GO:0007268 235 0.010
blood circulation GO:0008015 183 0.010
negative regulation of behavior GO:0048521 18 0.010

Pxdn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.010
cardiovascular system disease DOID:1287 0 0.010