Rattus norvegicus

22 known processes

Rac2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

(Aliases: MGC105983)

Rac2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 204 0.455
Human Zebrafish Rat Fly
cellular component assembly GO:0022607 360 0.410
Human Fly
cellular component biogenesis GO:0044085 368 0.377
Human Fly
cell activation GO:0001775 97 0.345
cell motility GO:0048870 202 0.307
Human Zebrafish Rat Fly
regulation of b cell differentiation GO:0045577 1 0.281
positive regulation of multicellular organismal process GO:0051240 387 0.259
regulation of immune system process GO:0002682 123 0.240
Human Zebrafish
protein complex subunit organization GO:0071822 302 0.222
Human Rat Fly
granulocyte chemotaxis GO:0071621 15 0.197
Human
cell projection organization GO:0030030 302 0.194
Human Fly
cellular component movement GO:0006928 248 0.193
Human Zebrafish Rat Fly
actin filament based process GO:0030029 86 0.186
macromolecular complex subunit organization GO:0043933 339 0.172
Human Rat Fly
localization of cell GO:0051674 202 0.172
Human Zebrafish Rat Fly
single organism organelle organization GO:1902589 180 0.161
amine metabolic process GO:0009308 38 0.161
leukocyte migration GO:0050900 38 0.152
Human Zebrafish Rat
regulation of cell motility GO:2000145 131 0.146
Human Zebrafish
cellular amino acid metabolic process GO:0006520 107 0.139
immune response GO:0006955 104 0.137
Fly
regulation of locomotion GO:0040012 148 0.134
Human Zebrafish
response to biotic stimulus GO:0009607 226 0.124
Fly
leukocyte chemotaxis GO:0030595 22 0.122
Human Rat
b cell differentiation GO:0030183 2 0.114
response to external biotic stimulus GO:0043207 221 0.112
Fly
neuron death GO:0070997 127 0.112
Rat
regulation of phosphate metabolic process GO:0019220 349 0.109
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.107
Rat
intracellular signal transduction GO:0035556 314 0.102
Rat Fly
regulation of cellular amine metabolic process GO:0033238 8 0.102
positive regulation of intracellular signal transduction GO:1902533 138 0.101
Rat
actin cytoskeleton organization GO:0030036 73 0.101
cell migration GO:0016477 197 0.099
Human Zebrafish Rat Fly
regulation of cellular amino acid metabolic process GO:0006521 2 0.098
macromolecular complex assembly GO:0065003 273 0.094
programmed cell death GO:0012501 392 0.093
Rat
positive regulation of protein modification process GO:0031401 142 0.092
protein complex biogenesis GO:0070271 263 0.091
regulation of protein metabolic process GO:0051246 289 0.090
cytoskeleton organization GO:0007010 111 0.090
regulation of anatomical structure size GO:0090066 135 0.087
cell projection morphogenesis GO:0048858 123 0.084
Fly
regulation of cell migration GO:0030334 128 0.081
Human Zebrafish
taxis GO:0042330 67 0.080
Human Rat
locomotion GO:0040011 237 0.079
Human Zebrafish Rat Fly
positive regulation of signaling GO:0023056 270 0.079
Rat
anatomical structure morphogenesis GO:0009653 298 0.079
Rat Fly
dephosphorylation GO:0016311 98 0.078
mapk cascade GO:0000165 140 0.075
Rat Fly
cellular amine metabolic process GO:0044106 38 0.074
positive regulation of biosynthetic process GO:0009891 319 0.073
Rat
regulation of cellular component movement GO:0051270 150 0.073
Human Zebrafish
organic acid metabolic process GO:0006082 292 0.072
hematopoietic progenitor cell differentiation GO:0002244 2 0.072
regulation of neuron death GO:1901214 115 0.072
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.070
protein phosphorylation GO:0006468 345 0.070
triglyceride homeostasis GO:0070328 2 0.068
response to wounding GO:0009611 254 0.068
Zebrafish Fly
negative regulation of cellular metabolic process GO:0031324 281 0.068
regulation of molecular function GO:0065009 398 0.068
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.068
regulation of protein modification process GO:0031399 194 0.068
regulation of cell morphogenesis GO:0022604 77 0.066
Fly
cell morphogenesis GO:0000902 142 0.065
Fly
positive regulation of cell communication GO:0010647 271 0.065
Rat
regulation of cell differentiation GO:0045595 320 0.065
Fly
positive regulation of signal transduction GO:0009967 175 0.064
Rat
positive regulation of cell differentiation GO:0045597 217 0.062
regulation of signal transduction GO:0009966 318 0.062
Rat
positive regulation of cellular component organization GO:0051130 200 0.062
Human Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.061
Rat
protein complex assembly GO:0006461 263 0.058
t cell activation GO:0042110 29 0.058
leukocyte activation GO:0045321 76 0.057
negative regulation of programmed cell death GO:0043069 183 0.056
sequestering of metal ion GO:0051238 9 0.056
neuron differentiation GO:0030182 368 0.055
Fly
divalent inorganic cation homeostasis GO:0072507 165 0.054
positive regulation of protein phosphorylation GO:0001934 135 0.054
carboxylic acid metabolic process GO:0019752 289 0.054
negative regulation of response to stimulus GO:0048585 155 0.053
peptidyl tyrosine phosphorylation GO:0018108 72 0.053
immune response activating signal transduction GO:0002757 15 0.053
defense response GO:0006952 194 0.053
Fly
negative regulation of apoptotic process GO:0043066 181 0.052
regulation of protein serine threonine kinase activity GO:0071900 64 0.052
positive regulation of cellular protein metabolic process GO:0032270 167 0.051
regulation of catalytic activity GO:0050790 304 0.051
Rat
positive regulation of cell motility GO:2000147 97 0.050
Human Zebrafish
cellular component morphogenesis GO:0032989 155 0.049
Fly
regulation of kinase activity GO:0043549 117 0.048
calcium ion transport into cytosol GO:0060402 38 0.048
cellular ketone metabolic process GO:0042180 51 0.048
positive regulation of neurogenesis GO:0050769 165 0.047
regulation of programmed cell death GO:0043067 341 0.047
Rat
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.047
positive regulation of catalytic activity GO:0043085 184 0.047
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.046
antibiotic transport GO:0042891 2 0.046
leukocyte cell cell adhesion GO:0007159 4 0.045
Human
positive regulation of response to stimulus GO:0048584 285 0.044
Human Rat Fly
mitotic spindle organization GO:0007052 2 0.044
positive regulation of phosphorylation GO:0042327 177 0.043
Rat
cation transport GO:0006812 382 0.043
regulation of transcription dna templated GO:0006355 374 0.043
central nervous system development GO:0007417 311 0.042
regulation of phosphorus metabolic process GO:0051174 349 0.041
Rat
peptidyl amino acid modification GO:0018193 126 0.041
metanephric glomerulus morphogenesis GO:0072275 1 0.041
regulation of homeostatic process GO:0032844 101 0.041
cellular homeostasis GO:0019725 252 0.040
metal ion transport GO:0030001 289 0.039
olfactory learning GO:0008355 1 0.039
neuron projection development GO:0031175 273 0.039
Fly
positive regulation of cell proliferation GO:0008284 249 0.038
peptidyl tyrosine modification GO:0018212 72 0.038
positive regulation of nervous system development GO:0051962 178 0.038
regulation of cell development GO:0060284 263 0.038
Fly
regulation of protein phosphorylation GO:0001932 183 0.038
regulation of cell proliferation GO:0042127 359 0.037
sequestering of calcium ion GO:0051208 8 0.037
regulation of protein kinase activity GO:0045859 105 0.036
regulation of rna metabolic process GO:0051252 391 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.036
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
regulation of neutrophil migration GO:1902622 6 0.036
Human
positive regulation of developmental process GO:0051094 283 0.035
cellular chemical homeostasis GO:0055082 247 0.035
organelle organization GO:0006996 266 0.035
regulation of actin filament based process GO:0032970 42 0.035
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.034
Fly
regulation of phosphorylation GO:0042325 248 0.034
Rat
divalent metal ion transport GO:0070838 132 0.034
rna metabolic process GO:0016070 406 0.034
proline transport GO:0015824 3 0.034
negative regulation of signal transduction GO:0009968 83 0.033
biological adhesion GO:0022610 110 0.033
Human
cellular response to endogenous stimulus GO:0071495 377 0.033
male sex determination GO:0030238 2 0.033
immune effector process GO:0002252 53 0.032
Zebrafish Fly
apoptotic process GO:0006915 381 0.032
Rat
positive regulation of cell migration GO:0030335 96 0.032
Human Zebrafish
positive regulation of cellular amine metabolic process GO:0033240 3 0.032
protein autophosphorylation GO:0046777 66 0.031
regulation of neurogenesis GO:0050767 247 0.031
Fly
positive regulation of gene expression GO:0010628 244 0.031
calcium ion homeostasis GO:0055074 162 0.031
macromolecule localization GO:0033036 252 0.031
Rat Fly
single organism cell adhesion GO:0098602 46 0.031
Human
neuron projection morphogenesis GO:0048812 122 0.030
Fly
regulation of intracellular signal transduction GO:1902531 218 0.030
Rat
cellular response to growth factor stimulus GO:0071363 162 0.030
positive regulation of hydrolase activity GO:0051345 86 0.030
regulation of mapk cascade GO:0043408 116 0.030
Rat
organ regeneration GO:0031100 101 0.029
spindle organization GO:0007051 2 0.029
positive regulation of cell development GO:0010720 176 0.029
cellular protein complex assembly GO:0043623 44 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
Rat
head development GO:0060322 247 0.028
regulation of immune response GO:0050776 55 0.028
single organism carbohydrate metabolic process GO:0044723 118 0.028
cell type specific apoptotic process GO:0097285 134 0.028
Rat
regulation of immunoglobulin production GO:0002637 4 0.028
regulation of leukocyte differentiation GO:1902105 20 0.028
regulation of apoptotic process GO:0042981 335 0.027
Rat
establishment of protein localization GO:0045184 141 0.027
Rat
positive regulation of protein metabolic process GO:0051247 178 0.027
cellular calcium ion homeostasis GO:0006874 160 0.027
single organism biosynthetic process GO:0044711 342 0.026
actin filament organization GO:0007015 42 0.026
Human Rat Fly
cellular response to molecule of fungal origin GO:0071226 1 0.026
regeneration GO:0031099 163 0.026
brain development GO:0007420 247 0.026
oxoacid metabolic process GO:0043436 290 0.025
cellular response to stress GO:0033554 269 0.025
Rat Fly
neuron development GO:0048666 286 0.025
Fly
cellular divalent inorganic cation homeostasis GO:0072503 162 0.025
release of sequestered calcium ion into cytosol GO:0051209 25 0.025
negative regulation of phosphate metabolic process GO:0045936 80 0.025
positive regulation of transport GO:0051050 245 0.025
Rat
vesicle docking involved in exocytosis GO:0006904 4 0.025
ion homeostasis GO:0050801 212 0.024
response to oxygen levels GO:0070482 265 0.024
regulation of cellular component size GO:0032535 51 0.024
positive regulation of protein kinase activity GO:0045860 73 0.024
response to bacterium GO:0009617 200 0.024
Fly
actin filament bundle assembly GO:0051017 19 0.024
Fly
negative regulation of metabolic process GO:0009892 331 0.024
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.024
cellular cation homeostasis GO:0030003 180 0.024
immune response regulating signaling pathway GO:0002764 19 0.024
chemotaxis GO:0006935 66 0.024
Human Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
Rat Fly
lymphocyte activation GO:0046649 43 0.023
chemical homeostasis GO:0048878 292 0.023
tissue development GO:0009888 252 0.023
Fly
response to hypoxia GO:0001666 231 0.023
platelet aggregation GO:0070527 4 0.023
regulation of cell projection organization GO:0031344 175 0.022
Human Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
Rat
homeostatic process GO:0042592 331 0.022
cell cell junction organization GO:0045216 20 0.022
Fly
positive regulation of kinase activity GO:0033674 77 0.022
cytosolic calcium ion homeostasis GO:0051480 140 0.022
rna biosynthetic process GO:0032774 380 0.022
muscle structure development GO:0061061 87 0.022
Fly
leukocyte homeostasis GO:0001776 7 0.022
Zebrafish
regulation of hormone levels GO:0010817 187 0.022
nucleic acid templated transcription GO:0097659 379 0.021
single organismal cell cell adhesion GO:0016337 42 0.021
Human
activation of mapk activity GO:0000187 33 0.021
glial cell differentiation GO:0010001 65 0.021
metal ion homeostasis GO:0055065 186 0.021
regulation of system process GO:0044057 208 0.021
response to nutrient levels GO:0031667 370 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
regulation of leukocyte migration GO:0002685 24 0.021
Human Zebrafish
behavior GO:0007610 205 0.021
Human Fly
mononuclear cell proliferation GO:0032943 29 0.021
divalent inorganic cation transport GO:0072511 134 0.021
cell part morphogenesis GO:0032990 123 0.020
Fly
regulation of cell activation GO:0050865 50 0.020
positive regulation of mapk cascade GO:0043410 92 0.020
Rat
regulation of protein complex assembly GO:0043254 33 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
Fly
secretion GO:0046903 307 0.020
positive regulation of molecular function GO:0044093 230 0.020
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
activation of immune response GO:0002253 26 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.019
Fly
negative regulation of cell death GO:0060548 229 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
positive regulation of cellular component movement GO:0051272 102 0.019
Human Zebrafish
cellular macromolecular complex assembly GO:0034622 58 0.019
positive regulation of secretion GO:0051047 140 0.019
regulation of calcium ion transport GO:0051924 77 0.019
positive regulation of immune system process GO:0002684 90 0.018
Human Zebrafish
cellular response to oxygen containing compound GO:1901701 386 0.018
lipid metabolic process GO:0006629 283 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
response to growth factor GO:0070848 189 0.018
leukocyte proliferation GO:0070661 29 0.018
endocytosis GO:0006897 84 0.018
Fly
signal transduction by phosphorylation GO:0023014 144 0.017
Rat Fly
cation homeostasis GO:0055080 195 0.017
regulation of transferase activity GO:0051338 123 0.017
defense response to gram negative bacterium GO:0050829 3 0.017
response to other organism GO:0051707 220 0.017
Fly
hemopoiesis GO:0030097 34 0.016
Fly
axis specification GO:0009798 4 0.016
Fly
negative regulation of neuron death GO:1901215 69 0.016
salivary gland development GO:0007431 3 0.016
Rat Fly
glycosaminoglycan biosynthetic process GO:0006024 4 0.016
wound healing GO:0042060 122 0.016
Fly
regulation of hexokinase activity GO:1903299 5 0.016
regulation of cytokinesis GO:0032465 3 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
negative regulation of viral process GO:0048525 4 0.015
positive regulation of mesonephros development GO:0061213 7 0.015
protein heterooligomerization GO:0051291 89 0.015
calcium ion transport GO:0006816 131 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
Fly
salivary gland morphogenesis GO:0007435 1 0.015
Rat Fly
cell adhesion mediated by integrin GO:0033627 1 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
Human
cellular metal ion homeostasis GO:0006875 172 0.015
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 1 0.015
regulation of t cell differentiation in thymus GO:0033081 1 0.014
regulation of neuron differentiation GO:0045664 208 0.014
Fly
positive regulation of organelle organization GO:0010638 48 0.014
neuron apoptotic process GO:0051402 88 0.014
Rat
acylglycerol homeostasis GO:0055090 2 0.014
response to yeast GO:0001878 3 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
regulation of cell adhesion GO:0030155 52 0.014
Human
defense response to gram positive bacterium GO:0050830 2 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
microtubule based process GO:0007017 36 0.014
Rat Fly
regulation of neuron projection development GO:0010975 161 0.014
Fly
muscle cell differentiation GO:0042692 52 0.014
activation of protein kinase activity GO:0032147 47 0.014
mast cell migration GO:0097531 4 0.014
Rat
regulation of neuron apoptotic process GO:0043523 83 0.013
Rat
regulation of heart morphogenesis GO:2000826 2 0.013
positive regulation of leukocyte degranulation GO:0043302 4 0.013
establishment of organelle localization GO:0051656 37 0.013
Rat
regulation of response to wounding GO:1903034 69 0.013
Fly
regulation of ion homeostasis GO:2000021 63 0.013
positive regulation of locomotion GO:0040017 102 0.013
Human Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
mast cell activation involved in immune response GO:0002279 10 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
pro t cell differentiation GO:0002572 1 0.013
neurological system process GO:0050877 219 0.013
regulation of cell size GO:0008361 37 0.013
regulation of cellular component organization GO:0051128 368 0.012
Human Rat Fly
cell cell signaling GO:0007267 335 0.012
Rat Fly
reproduction GO:0000003 245 0.012
Fly
positive regulation of neuron differentiation GO:0045666 126 0.012
cell cycle GO:0007049 101 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
alcohol metabolic process GO:0006066 77 0.012
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.012
response to extracellular stimulus GO:0009991 380 0.012
organelle localization GO:0051640 55 0.012
Rat
immunoglobulin mediated immune response GO:0016064 4 0.012
cell proliferation involved in heart morphogenesis GO:0061323 2 0.012
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
Fly
regulation of organelle organization GO:0033043 80 0.012
negative regulation of cell development GO:0010721 82 0.012
olfactory behavior GO:0042048 2 0.012
negative regulation of homeostatic process GO:0032845 47 0.012
negative regulation of neuron apoptotic process GO:0043524 45 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
negative regulation of cell communication GO:0010648 158 0.012
growth GO:0040007 165 0.012
Fly
dorsal ventral pattern formation GO:0009953 4 0.011
circulatory system development GO:0072359 134 0.011
Rat
regulation of nervous system development GO:0051960 264 0.011
Fly
response to acid chemical GO:0001101 222 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.011
protein transport GO:0015031 132 0.011
Rat
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
immune system development GO:0002520 41 0.011
Fly
cellular response to external stimulus GO:0071496 118 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
cellular response to lipid GO:0071396 201 0.011
transcription dna templated GO:0006351 377 0.011
cell chemotaxis GO:0060326 31 0.011
Human Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
positive regulation of transferase activity GO:0051347 81 0.011
regulation of intracellular transport GO:0032386 65 0.011
Rat
anion transport GO:0006820 178 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
Rat
t cell migration GO:0072678 2 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.010
Human
chemosensory behavior GO:0007635 2 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
Fly
actin polymerization or depolymerization GO:0008154 14 0.010
negative regulation of molecular function GO:0044092 133 0.010
vesicle mediated transport GO:0016192 181 0.010
Fly
insulin receptor signaling pathway GO:0008286 24 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
response to decreased oxygen levels GO:0036293 237 0.010
neutrophil migration GO:1990266 12 0.010
Human

Rac2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org