Rattus norvegicus

0 known processes

Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

(Aliases: MGC124613,Epac)

Rapgef3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.299
transcription dna templated GO:0006351 377 0.287
cellular response to endogenous stimulus GO:0071495 377 0.238
Human Rat
regulation of cellular localization GO:0060341 263 0.235
cellular component movement GO:0006928 248 0.233
Rat
single organism biosynthetic process GO:0044711 342 0.215
apoptotic process GO:0006915 381 0.214
intracellular signal transduction GO:0035556 314 0.195
Human Rat
secretion GO:0046903 307 0.186
regulation of apoptotic process GO:0042981 335 0.186
cell motility GO:0048870 202 0.183
Rat
regulation of rna metabolic process GO:0051252 391 0.178
regulation of catalytic activity GO:0050790 304 0.178
Human Mouse Rat
cation transport GO:0006812 382 0.166
regulation of phosphorus metabolic process GO:0051174 349 0.162
Human Mouse Rat
macromolecule localization GO:0033036 252 0.159
cell cell signaling GO:0007267 335 0.158
Rat
regulation of molecular function GO:0065009 398 0.158
Human Mouse Rat
homeostatic process GO:0042592 331 0.153
anatomical structure morphogenesis GO:0009653 298 0.151
Human
cellular response to nitrogen compound GO:1901699 210 0.145
Human
circulatory system process GO:0003013 183 0.142
programmed cell death GO:0012501 392 0.135
behavior GO:0007610 205 0.134
localization of cell GO:0051674 202 0.133
Rat
neurological system process GO:0050877 219 0.133
secretion by cell GO:0032940 248 0.130
blood circulation GO:0008015 183 0.128
regulation of blood vessel size GO:0050880 89 0.125
regulation of nucleic acid templated transcription GO:1903506 380 0.125
positive regulation of signaling GO:0023056 270 0.123
Rat
organophosphate metabolic process GO:0019637 370 0.118
Human Mouse Rat
rna metabolic process GO:0016070 406 0.116
cellular component assembly GO:0022607 360 0.114
Human
regulation of cellular component movement GO:0051270 150 0.108
Rat
regulation of transcription dna templated GO:0006355 374 0.107
regulation of protein metabolic process GO:0051246 289 0.105
Rat
regulation of phosphate metabolic process GO:0019220 349 0.103
Human Mouse Rat
regulation of phosphorylation GO:0042325 248 0.103
Rat
regulation of blood circulation GO:1903522 110 0.103
regulation of cellular component organization GO:0051128 368 0.101
Human Rat
regulation of cell proliferation GO:0042127 359 0.097
negative regulation of metabolic process GO:0009892 331 0.096
positive regulation of phosphate metabolic process GO:0045937 262 0.095
Human Mouse Rat
regulation of secretion by cell GO:1903530 208 0.095
mapk cascade GO:0000165 140 0.094
Rat
tissue development GO:0009888 252 0.094
Human
g protein coupled receptor signaling pathway GO:0007186 242 0.091
chemotaxis GO:0006935 66 0.091
cardiovascular system development GO:0072358 134 0.090
Human Rat
nucleic acid templated transcription GO:0097659 379 0.090
response to metal ion GO:0010038 253 0.089
regulation of system process GO:0044057 208 0.089
response to oxygen levels GO:0070482 265 0.089
regulation of rna biosynthetic process GO:2001141 381 0.089
cellular component biogenesis GO:0044085 368 0.089
Human
locomotion GO:0040011 237 0.088
Rat
heart contraction GO:0060047 57 0.088
regulation of programmed cell death GO:0043067 341 0.087
cell migration GO:0016477 197 0.086
Rat
neuron differentiation GO:0030182 368 0.085
Rat
regulation of tube size GO:0035150 89 0.084
ion homeostasis GO:0050801 212 0.083
positive regulation of transport GO:0051050 245 0.081
organic acid metabolic process GO:0006082 292 0.079
regulation of hydrolase activity GO:0051336 143 0.077
Human Mouse Rat
regulation of ion transport GO:0043269 245 0.077
regulation of cellular protein metabolic process GO:0032268 267 0.076
Rat
single organism behavior GO:0044708 130 0.076
regulation of secretion GO:0051046 224 0.075
regulation of heart contraction GO:0008016 48 0.075
rna biosynthetic process GO:0032774 380 0.074
single organism organelle organization GO:1902589 180 0.073
Human
positive regulation of cell death GO:0010942 184 0.073
positive regulation of programmed cell death GO:0043068 157 0.073
macromolecular complex subunit organization GO:0043933 339 0.071
Human
positive regulation of molecular function GO:0044093 230 0.071
Human Mouse Rat
immune system process GO:0002376 204 0.069
divalent metal ion transport GO:0070838 132 0.068
transcription from rna polymerase ii promoter GO:0006366 252 0.068
regulation of anatomical structure size GO:0090066 135 0.067
positive regulation of apoptotic process GO:0043065 154 0.066
response to wounding GO:0009611 254 0.066
positive regulation of cell motility GO:2000147 97 0.066
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.065
regulation of multicellular organismal development GO:2000026 376 0.065
Human Rat
regulation of neurogenesis GO:0050767 247 0.065
Rat
neuron development GO:0048666 286 0.064
Rat
oxoacid metabolic process GO:0043436 290 0.063
positive regulation of gene expression GO:0010628 244 0.062
cellular ion homeostasis GO:0006873 184 0.062
negative regulation of macromolecule metabolic process GO:0010605 260 0.062
negative regulation of multicellular organismal process GO:0051241 203 0.062
chemical homeostasis GO:0048878 292 0.061
nitrogen compound transport GO:0071705 229 0.061
positive regulation of nucleic acid templated transcription GO:1903508 197 0.061
regulation of signal transduction GO:0009966 318 0.061
Human Rat
cellular cation homeostasis GO:0030003 180 0.060
regulation of intracellular signal transduction GO:1902531 218 0.060
Human Rat
response to extracellular stimulus GO:0009991 380 0.060
positive regulation of cellular biosynthetic process GO:0031328 295 0.059
carbohydrate derivative metabolic process GO:1901135 346 0.059
Human Mouse Rat
response to peptide GO:1901652 292 0.058
growth GO:0040007 165 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.058
Human Mouse Rat
metal ion homeostasis GO:0055065 186 0.058
catabolic process GO:0009056 351 0.058
Human Mouse Rat
synaptic transmission GO:0007268 235 0.057
Rat
positive regulation of cell communication GO:0010647 271 0.057
Rat
muscle system process GO:0003012 115 0.057
response to purine containing compound GO:0014074 126 0.057
Human
calcium ion homeostasis GO:0055074 162 0.057
carbohydrate metabolic process GO:0005975 130 0.057
divalent inorganic cation transport GO:0072511 134 0.057
vascular process in circulatory system GO:0003018 96 0.056
positive regulation of signal transduction GO:0009967 175 0.056
Rat
positive regulation of secretion by cell GO:1903532 128 0.055
organic substance catabolic process GO:1901575 316 0.055
Human Mouse Rat
defense response GO:0006952 194 0.055
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.054
cellular metal ion homeostasis GO:0006875 172 0.053
cellular lipid metabolic process GO:0044255 208 0.053
heart process GO:0003015 57 0.052
organophosphate biosynthetic process GO:0090407 143 0.052
cellular amino acid metabolic process GO:0006520 107 0.052
protein complex assembly GO:0006461 263 0.052
cellular protein localization GO:0034613 122 0.052
regulation of metal ion transport GO:0010959 118 0.051
cardiac muscle contraction GO:0060048 27 0.051
purine ribonucleotide metabolic process GO:0009150 227 0.051
Human Mouse Rat
circulatory system development GO:0072359 134 0.050
Human Rat
regulation of protein phosphorylation GO:0001932 183 0.050
Rat
response to ketone GO:1901654 182 0.050
inflammatory response GO:0006954 150 0.049
metal ion transport GO:0030001 289 0.048
positive regulation of phosphorus metabolic process GO:0010562 262 0.048
Human Mouse Rat
cation homeostasis GO:0055080 195 0.048
response to hypoxia GO:0001666 231 0.048
rhythmic process GO:0048511 156 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
Human Mouse Rat
carboxylic acid metabolic process GO:0019752 289 0.046
organophosphate catabolic process GO:0046434 148 0.046
Human Mouse Rat
positive regulation of phosphorylation GO:0042327 177 0.045
Rat
cell projection organization GO:0030030 302 0.044
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.044
positive regulation of catalytic activity GO:0043085 184 0.044
Human Mouse Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.043
learning or memory GO:0007611 90 0.043
blood vessel morphogenesis GO:0048514 58 0.043
Human
positive regulation of biosynthetic process GO:0009891 319 0.043
muscle contraction GO:0006936 88 0.042
single organism catabolic process GO:0044712 283 0.042
Human Mouse Rat
signal release GO:0023061 145 0.042
action potential GO:0001508 54 0.042
lipid biosynthetic process GO:0008610 128 0.041
purine nucleotide metabolic process GO:0006163 229 0.041
Human Mouse Rat
positive regulation of cell migration GO:0030335 96 0.040
Rat
central nervous system development GO:0007417 311 0.040
response to nutrient levels GO:0031667 370 0.040
cognition GO:0050890 92 0.040
signal transduction by phosphorylation GO:0023014 144 0.040
Rat
organelle organization GO:0006996 266 0.040
Human
cellular divalent inorganic cation homeostasis GO:0072503 162 0.040
positive regulation of cellular component organization GO:0051130 200 0.040
Human Rat
positive regulation of cellular component movement GO:0051272 102 0.040
Rat
response to peptide hormone GO:0043434 278 0.039
protein phosphorylation GO:0006468 345 0.039
Rat
sensory perception GO:0007600 101 0.039
regulation of blood pressure GO:0008217 83 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
Human
cellular response to organonitrogen compound GO:0071417 197 0.038
Human
negative regulation of programmed cell death GO:0043069 183 0.038
nucleotide metabolic process GO:0009117 279 0.038
Human Mouse Rat
vesicle mediated transport GO:0016192 181 0.038
negative regulation of gene expression GO:0010629 199 0.038
calcium ion transport GO:0006816 131 0.037
lipid metabolic process GO:0006629 283 0.037
reproductive process GO:0022414 372 0.037
cellular homeostasis GO:0019725 252 0.037
regulation of homeostatic process GO:0032844 101 0.036
protein complex biogenesis GO:0070271 263 0.036
mechanoreceptor differentiation GO:0042490 2 0.035
endocytosis GO:0006897 84 0.035
transmission of nerve impulse GO:0019226 42 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.035
enzyme linked receptor protein signaling pathway GO:0007167 116 0.035
Rat
regulation of immune system process GO:0002682 123 0.035
regulation of cell growth GO:0001558 85 0.035
neuron projection development GO:0031175 273 0.035
Rat
transmembrane transport GO:0055085 412 0.035
cellular response to stress GO:0033554 269 0.034
protein complex subunit organization GO:0071822 302 0.034
Human
regulation of cell motility GO:2000145 131 0.034
Rat
positive regulation of rna metabolic process GO:0051254 203 0.034
actin filament based process GO:0030029 86 0.034
Human
ribonucleotide metabolic process GO:0009259 231 0.034
Human Mouse Rat
regulation of kinase activity GO:0043549 117 0.034
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.034
negative regulation of cell communication GO:0010648 158 0.033
Rat
negative regulation of apoptotic process GO:0043066 181 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
Human Rat
b cell differentiation GO:0030183 2 0.033
cellular component morphogenesis GO:0032989 155 0.033
regulation of membrane potential GO:0042391 110 0.032
response to decreased oxygen levels GO:0036293 237 0.032
insulin secretion GO:0030073 69 0.032
negative regulation of biosynthetic process GO:0009890 168 0.032
purine ribonucleotide catabolic process GO:0009154 136 0.032
Human Mouse Rat
positive regulation of cell proliferation GO:0008284 249 0.032
angiogenesis GO:0001525 53 0.031
Human
protein localization GO:0008104 191 0.031
hormone transport GO:0009914 121 0.031
regulation of synaptic plasticity GO:0048167 70 0.031
Rat
negative regulation of response to stimulus GO:0048585 155 0.031
macromolecular complex assembly GO:0065003 273 0.031
cytoskeleton organization GO:0007010 111 0.031
Human
positive regulation of cell differentiation GO:0045597 217 0.031
Rat
membrane organization GO:0061024 94 0.031
purine containing compound metabolic process GO:0072521 253 0.030
Human Mouse Rat
cellular amine metabolic process GO:0044106 38 0.030
response to oxidative stress GO:0006979 186 0.030
phospholipid metabolic process GO:0006644 61 0.030
positive regulation of intracellular signal transduction GO:1902533 138 0.030
Rat
protein transport GO:0015031 132 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
Rat
sensory perception of pain GO:0019233 73 0.030
negative regulation of developmental process GO:0051093 125 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
Human Mouse Rat
regulation of behavior GO:0050795 61 0.030
response to hydrogen peroxide GO:0042542 89 0.030
immune response GO:0006955 104 0.030
cellular response to growth factor stimulus GO:0071363 162 0.030
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
Rat
response to biotic stimulus GO:0009607 226 0.030
cellular catabolic process GO:0044248 295 0.029
Human Mouse Rat
response to growth factor GO:0070848 189 0.029
Rat
peptidyl amino acid modification GO:0018193 126 0.029
response to insulin GO:0032868 133 0.029
regulation of cell migration GO:0030334 128 0.029
Rat
vasoconstriction GO:0042310 54 0.029
multi organism reproductive process GO:0044703 262 0.029
smooth muscle cell proliferation GO:0048659 77 0.029
intracellular transport GO:0046907 185 0.029
regulation of cell development GO:0060284 263 0.029
Rat
anatomical structure formation involved in morphogenesis GO:0048646 83 0.029
Human
small molecule biosynthetic process GO:0044283 124 0.028
amine metabolic process GO:0009308 38 0.028
cellular carbohydrate metabolic process GO:0044262 72 0.028
cation transmembrane transport GO:0098655 263 0.028
positive regulation of hydrolase activity GO:0051345 86 0.028
Human Mouse Rat
divalent inorganic cation homeostasis GO:0072507 165 0.028
hormone secretion GO:0046879 115 0.028
single organism membrane organization GO:0044802 74 0.027
regulation of protein modification process GO:0031399 194 0.027
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
Rat
regulation of muscle contraction GO:0006937 53 0.027
response to cytokine GO:0034097 215 0.027
regulation of neuron differentiation GO:0045664 208 0.027
Rat
positive regulation of secretion GO:0051047 140 0.026
cellular response to cytokine stimulus GO:0071345 127 0.026
carbohydrate derivative catabolic process GO:1901136 147 0.026
Human Mouse Rat
mesoderm development GO:0007498 2 0.026
ion transmembrane transport GO:0034220 365 0.026
regulation of transferase activity GO:0051338 123 0.026
Rat
response to monosaccharide GO:0034284 159 0.026
regulation of cell differentiation GO:0045595 320 0.026
Rat
potassium ion transport GO:0006813 97 0.025
multicellular organism reproduction GO:0032504 233 0.025
wound healing GO:0042060 122 0.025
reproductive structure development GO:0048608 128 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.025
muscle cell proliferation GO:0033002 84 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
regulation of nervous system development GO:0051960 264 0.025
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.025
response to other organism GO:0051707 220 0.025
multicellular organismal signaling GO:0035637 44 0.025
regulation of anatomical structure morphogenesis GO:0022603 141 0.025
Human
positive regulation of mapk cascade GO:0043410 92 0.024
Rat
ribonucleoside metabolic process GO:0009119 174 0.024
Human Mouse Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
Human
regulation of small gtpase mediated signal transduction GO:0051056 48 0.024
Human Rat
regulation of angiogenesis GO:0045765 39 0.024
Human
response to nutrient GO:0007584 248 0.024
response to toxic substance GO:0009636 133 0.024
sexual reproduction GO:0019953 148 0.024
purine nucleoside triphosphate metabolic process GO:0009144 141 0.024
Human Mouse Rat
monovalent inorganic cation transport GO:0015672 172 0.024
cellular calcium ion homeostasis GO:0006874 160 0.024
aging GO:0007568 241 0.024
ribonucleotide biosynthetic process GO:0009260 85 0.024
response to alkaloid GO:0043279 132 0.023
regulation of muscle system process GO:0090257 79 0.023
cell growth GO:0016049 104 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
Human Mouse Rat
nucleoside phosphate metabolic process GO:0006753 283 0.023
Human Mouse Rat
ras protein signal transduction GO:0007265 29 0.023
Human
organonitrogen compound biosynthetic process GO:1901566 167 0.023
negative regulation of cell proliferation GO:0008285 119 0.023
positive regulation of locomotion GO:0040017 102 0.023
Rat
regulation of nucleotide biosynthetic process GO:0030808 47 0.023
positive regulation of nervous system development GO:0051962 178 0.022
Rat
response to acid chemical GO:0001101 222 0.022
response to hexose GO:0009746 144 0.022
gland development GO:0048732 155 0.022
developmental growth GO:0048589 100 0.022
positive regulation of cell development GO:0010720 176 0.022
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
negative regulation of cell death GO:0060548 229 0.022
regulation of endothelial cell differentiation GO:0045601 4 0.022
negative regulation of rna metabolic process GO:0051253 123 0.022
negative regulation of signaling GO:0023057 157 0.022
Rat
cyclic nucleotide metabolic process GO:0009187 80 0.022
cellular macromolecule localization GO:0070727 122 0.022
response to mechanical stimulus GO:0009612 134 0.022
response to glucocorticoid GO:0051384 223 0.021
renal system development GO:0072001 67 0.021
brain development GO:0007420 247 0.021
cardiac muscle cell contraction GO:0086003 10 0.021
single organism reproductive process GO:0044702 297 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
response to corticosteroid GO:0031960 235 0.021
regulation of hormone levels GO:0010817 187 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
nucleoside metabolic process GO:0009116 179 0.021
Human Mouse Rat
positive regulation of transcription dna templated GO:0045893 197 0.021
negative regulation of molecular function GO:0044092 133 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
ribose phosphate biosynthetic process GO:0046390 87 0.021
cellular ketone metabolic process GO:0042180 51 0.021
motor neuron axon guidance GO:0008045 1 0.021
single organism intracellular transport GO:1902582 166 0.021
response to mineralocorticoid GO:0051385 49 0.020
protein oligomerization GO:0051259 191 0.020
memory GO:0007613 54 0.020
oxidation reduction process GO:0055114 304 0.020
neuron neuron synaptic transmission GO:0007270 60 0.020
reproduction GO:0000003 245 0.020
glycerolipid metabolic process GO:0046486 67 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
cell fate determination GO:0001709 2 0.020
negative regulation of phosphate metabolic process GO:0045936 80 0.020
cyclic purine nucleotide metabolic process GO:0052652 62 0.020
regulation of synaptic transmission GO:0050804 141 0.020
Rat
regulation of mapk cascade GO:0043408 116 0.020
Rat
response to carbohydrate GO:0009743 183 0.020
protein homooligomerization GO:0051260 91 0.020
peptide hormone secretion GO:0030072 84 0.020
muscle structure development GO:0061061 87 0.020
cellular chemical homeostasis GO:0055082 247 0.020
response to ammonium ion GO:0060359 71 0.019
peptide secretion GO:0002790 86 0.019
negative regulation of transport GO:0051051 136 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
Human Mouse Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
ribonucleoside triphosphate catabolic process GO:0009203 122 0.019
Human Mouse Rat
nucleoside phosphate catabolic process GO:1901292 140 0.019
Human Mouse Rat
cellular response to peptide GO:1901653 133 0.019
cell part morphogenesis GO:0032990 123 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
peptide transport GO:0015833 97 0.019
cyclic nucleotide biosynthetic process GO:0009190 63 0.019
positive regulation of nucleotide metabolic process GO:0045981 91 0.019
Human Mouse Rat
multicellular organismal reproductive process GO:0048609 233 0.019
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.019
aromatic compound catabolic process GO:0019439 168 0.019
Human Mouse Rat
amide transport GO:0042886 105 0.019
purine containing compound catabolic process GO:0072523 138 0.018
Human Mouse Rat
urogenital system development GO:0001655 78 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
regulation of organ formation GO:0003156 2 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.018
Human Mouse Rat
regulation of hormone secretion GO:0046883 106 0.018
vasculature development GO:0001944 70 0.018
Human
response to temperature stimulus GO:0009266 94 0.018
amine transport GO:0015837 57 0.018
single organism cellular localization GO:1902580 102 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
proteolysis GO:0006508 175 0.017
cell cycle GO:0007049 101 0.017
axon ensheathment GO:0008366 40 0.017
neuron fate commitment GO:0048663 4 0.017
regulation of body fluid levels GO:0050878 90 0.017
bmp signaling pathway GO:0030509 4 0.017
cellular response to insulin stimulus GO:0032869 81 0.017
nucleotide biosynthetic process GO:0009165 98 0.017
anion transport GO:0006820 178 0.017
generation of precursor metabolites and energy GO:0006091 62 0.017
gastrulation GO:0007369 2 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
Rat
receptor mediated endocytosis GO:0006898 42 0.017
developmental process involved in reproduction GO:0003006 159 0.017
negative regulation of catalytic activity GO:0043086 103 0.017
purine ribonucleotide biosynthetic process GO:0009152 81 0.017
tube development GO:0035295 89 0.017
establishment of protein localization GO:0045184 141 0.017
regulation of neurological system process GO:0031644 43 0.017
heart morphogenesis GO:0003007 3 0.017
negative regulation of hormone secretion GO:0046888 46 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
Human Mouse Rat
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
regulation of b cell differentiation GO:0045577 1 0.017
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.016
positive regulation of protein modification process GO:0031401 142 0.016
Rat
positive regulation of neuron projection development GO:0010976 99 0.016
Rat
exocytosis GO:0006887 60 0.016
glomerular visceral epithelial cell development GO:0072015 2 0.016
erythrocyte differentiation GO:0030218 1 0.016
multi multicellular organism process GO:0044706 138 0.016
regulation of growth GO:0040008 105 0.016
regulation of striated muscle contraction GO:0006942 21 0.016
circadian rhythm GO:0007623 88 0.016
developmental induction GO:0031128 2 0.016
reproductive system development GO:0061458 128 0.016
response to reactive oxygen species GO:0000302 120 0.016
negative regulation of signal transduction GO:0009968 83 0.016
response to lipopolysaccharide GO:0032496 191 0.015
kidney development GO:0001822 67 0.015
protein maturation GO:0051604 68 0.015
negative regulation of secretion GO:0051048 82 0.015
cell activation GO:0001775 97 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
membrane repolarization GO:0086009 1 0.015
reactive oxygen species metabolic process GO:0072593 37 0.015
regulation of protein localization GO:0032880 81 0.015
regulation of response to external stimulus GO:0032101 106 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
regulation of insulin secretion GO:0050796 65 0.015
somatic stem cell division GO:0048103 2 0.015
cytoplasmic transport GO:0016482 115 0.015
regeneration GO:0031099 163 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
Rat
glycosyl compound catabolic process GO:1901658 126 0.015
Human Mouse Rat
multicellular organismal homeostasis GO:0048871 49 0.015
head development GO:0060322 247 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
Human Mouse Rat
purine nucleotide catabolic process GO:0006195 136 0.015
Human Mouse Rat
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.015
positive regulation of blood circulation GO:1903524 65 0.015
response to external biotic stimulus GO:0043207 221 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
Human Mouse Rat
purine containing compound biosynthetic process GO:0072522 85 0.015
cellular response to external stimulus GO:0071496 118 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
Human Mouse Rat
organonitrogen compound catabolic process GO:1901565 179 0.014
Human Mouse Rat
negative regulation of ion transport GO:0043271 51 0.014
gtp catabolic process GO:0006184 71 0.014
Human Mouse Rat
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
biological adhesion GO:0022610 110 0.014
regulation of cell projection organization GO:0031344 175 0.014
Rat
gamete generation GO:0007276 124 0.014
cell morphogenesis GO:0000902 142 0.014
forebrain development GO:0030900 98 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
regulation of calcium ion transport GO:0051924 77 0.014
auditory receptor cell differentiation GO:0042491 2 0.014
regulation of locomotion GO:0040012 148 0.014
Rat
detection of stimulus GO:0051606 24 0.014
inner ear receptor cell differentiation GO:0060113 2 0.014
rho protein signal transduction GO:0007266 11 0.014
regulation of peptide secretion GO:0002791 82 0.014
heterocycle catabolic process GO:0046700 167 0.014
Human Mouse Rat
lymphoid progenitor cell differentiation GO:0002320 2 0.014
neuron projection morphogenesis GO:0048812 122 0.014
energy derivation by oxidation of organic compounds GO:0015980 46 0.014
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.014
striated muscle contraction GO:0006941 44 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
blood vessel development GO:0001568 69 0.014
Human
response to fatty acid GO:0070542 65 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.013
regulation of cytoskeleton organization GO:0051493 49 0.013
Human
defense response to gram negative bacterium GO:0050829 3 0.013
dna metabolic process GO:0006259 96 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
cell type specific apoptotic process GO:0097285 134 0.013
regulation of camp metabolic process GO:0030814 43 0.013
regulation of neuron projection development GO:0010975 161 0.013
Rat

Rapgef3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
cardiovascular system disease DOID:1287 0 0.036
vascular disease DOID:178 0 0.034
hypertension DOID:10763 0 0.027
artery disease DOID:0050828 0 0.027
essential hypertension DOID:10825 0 0.027
central nervous system disease DOID:331 0 0.015
nervous system disease DOID:863 0 0.015