Rattus norvegicus

182 known processes

Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

(Aliases: CAMP-GEFII,CAMPS,Epac2,Cgef2)

Rapgef4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.259
intracellular signal transduction GO:0035556 314 0.232
Mouse Rat
secretion GO:0046903 307 0.115
Mouse
nitrogen compound transport GO:0071705 229 0.113
Mouse
cellular response to stress GO:0033554 269 0.112
carboxylic acid metabolic process GO:0019752 289 0.112
behavior GO:0007610 205 0.100
regulation of phosphorus metabolic process GO:0051174 349 0.098
cell cell signaling GO:0007267 335 0.095
response to nutrient GO:0007584 248 0.095
protein dephosphorylation GO:0006470 38 0.095
regulation of molecular function GO:0065009 398 0.090
regulation of cell development GO:0060284 263 0.089
learning or memory GO:0007611 90 0.088
cellular response to oxygen containing compound GO:1901701 386 0.086
neuron development GO:0048666 286 0.086
response to nutrient levels GO:0031667 370 0.080
lipid metabolic process GO:0006629 283 0.077
memory GO:0007613 54 0.077
cell projection organization GO:0030030 302 0.077
response to peptide GO:1901652 292 0.074
multi organism reproductive process GO:0044703 262 0.072
positive regulation of catalytic activity GO:0043085 184 0.070
transcription dna templated GO:0006351 377 0.069
regulation of signal transduction GO:0009966 318 0.068
Mouse Rat
positive regulation of secretion GO:0051047 140 0.067
neuron differentiation GO:0030182 368 0.066
neuronal action potential GO:0019228 35 0.066
response to extracellular stimulus GO:0009991 380 0.065
cellular component assembly GO:0022607 360 0.063
response to peptide hormone GO:0043434 278 0.063
head development GO:0060322 247 0.062
metal ion transport GO:0030001 289 0.062
regulation of membrane potential GO:0042391 110 0.061
neuron projection development GO:0031175 273 0.061
protein complex subunit organization GO:0071822 302 0.060
anion transport GO:0006820 178 0.059
positive regulation of locomotion GO:0040017 102 0.059
synaptic transmission GO:0007268 235 0.058
nucleic acid templated transcription GO:0097659 379 0.057
reproductive process GO:0022414 372 0.057
inorganic ion transmembrane transport GO:0098660 229 0.057
response to carbohydrate GO:0009743 183 0.057
homeostatic process GO:0042592 331 0.056
response to oxygen levels GO:0070482 265 0.056
neurological system process GO:0050877 219 0.055
positive regulation of transport GO:0051050 245 0.054
single organism biosynthetic process GO:0044711 342 0.054
oxoacid metabolic process GO:0043436 290 0.054
cellular lipid metabolic process GO:0044255 208 0.053
organic acid metabolic process GO:0006082 292 0.053
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.053
regulation of phosphate metabolic process GO:0019220 349 0.052
ion homeostasis GO:0050801 212 0.051
response to cytokine GO:0034097 215 0.051
transmembrane transport GO:0055085 412 0.051
regulation of cell proliferation GO:0042127 359 0.051
reproduction GO:0000003 245 0.051
single organism behavior GO:0044708 130 0.050
rna metabolic process GO:0016070 406 0.050
programmed cell death GO:0012501 392 0.049
regulation of cellular ketone metabolic process GO:0010565 27 0.048
signal release GO:0023061 145 0.048
Mouse
regulation of nervous system development GO:0051960 264 0.047
cellular amine metabolic process GO:0044106 38 0.047
positive regulation of cell proliferation GO:0008284 249 0.046
catabolic process GO:0009056 351 0.046
negative regulation of signaling GO:0023057 157 0.046
chemical homeostasis GO:0048878 292 0.045
central nervous system development GO:0007417 311 0.045
response to glucose GO:0009749 136 0.044
positive regulation of cell motility GO:2000147 97 0.044
sexual reproduction GO:0019953 148 0.044
multicellular organismal reproductive process GO:0048609 233 0.044
regulation of neurogenesis GO:0050767 247 0.044
regulation of catabolic process GO:0009894 113 0.043
regulation of cellular catabolic process GO:0031329 101 0.043
positive regulation of transcription factor import into nucleus GO:0042993 4 0.043
multicellular organism reproduction GO:0032504 233 0.042
rhythmic process GO:0048511 156 0.042
regulation of transcription dna templated GO:0006355 374 0.042
single organism reproductive process GO:0044702 297 0.042
negative regulation of transport GO:0051051 136 0.041
regulation of cellular component movement GO:0051270 150 0.041
rna biosynthetic process GO:0032774 380 0.041
regulation of cellular component organization GO:0051128 368 0.041
organic substance catabolic process GO:1901575 316 0.040
response to monosaccharide GO:0034284 159 0.040
protein localization GO:0008104 191 0.040
organophosphate metabolic process GO:0019637 370 0.040
neuron projection morphogenesis GO:0048812 122 0.039
dephosphorylation GO:0016311 98 0.039
regulation of cell differentiation GO:0045595 320 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
regulation of response to stress GO:0080134 126 0.039
response to hexose GO:0009746 144 0.039
cellular homeostasis GO:0019725 252 0.039
positive regulation of cell migration GO:0030335 96 0.039
cellular response to peptide GO:1901653 133 0.038
response to interleukin 15 GO:0070672 4 0.038
multi multicellular organism process GO:0044706 138 0.038
regulation of cellular localization GO:0060341 263 0.038
Mouse
cellular response to hormone stimulus GO:0032870 247 0.038
regulation of hormone levels GO:0010817 187 0.038
Mouse
regulation of multicellular organismal development GO:2000026 376 0.037
cellular response to endogenous stimulus GO:0071495 377 0.037
Rat
cellular component movement GO:0006928 248 0.037
regulation of neuron death GO:1901214 115 0.037
response to metal ion GO:0010038 253 0.036
regulation of homeostatic process GO:0032844 101 0.036
regulation of cell projection organization GO:0031344 175 0.036
negative regulation of nucleic acid templated transcription GO:1903507 117 0.036
cellular response to peptide hormone stimulus GO:0071375 120 0.036
secretion by cell GO:0032940 248 0.035
Mouse
positive regulation of cell communication GO:0010647 271 0.035
Rat
positive regulation of signal transduction GO:0009967 175 0.035
Rat
cellular chemical homeostasis GO:0055082 247 0.035
regulation of system process GO:0044057 208 0.035
regulation of catalytic activity GO:0050790 304 0.035
transcription from rna polymerase ii promoter GO:0006366 252 0.034
regulation of secretion GO:0051046 224 0.034
Mouse
positive regulation of neuron projection development GO:0010976 99 0.034
Rat
macromolecular complex assembly GO:0065003 273 0.033
cellular ketone metabolic process GO:0042180 51 0.033
cation transmembrane transport GO:0098655 263 0.033
response to purine containing compound GO:0014074 126 0.033
cellular response to organonitrogen compound GO:0071417 197 0.033
transmission of nerve impulse GO:0019226 42 0.033
protein complex biogenesis GO:0070271 263 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.032
negative regulation of multicellular organismal process GO:0051241 203 0.032
synaptic vesicle priming GO:0016082 4 0.032
regulation of ion transport GO:0043269 245 0.032
lipid biosynthetic process GO:0008610 128 0.032
neuron death GO:0070997 127 0.032
cellular catabolic process GO:0044248 295 0.032
cellular cation homeostasis GO:0030003 180 0.032
amide transport GO:0042886 105 0.031
Mouse
macromolecule localization GO:0033036 252 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
regulation of protein phosphorylation GO:0001932 183 0.031
Rat
establishment of tissue polarity GO:0007164 2 0.031
positive regulation of nervous system development GO:0051962 178 0.031
Rat
regulation of synaptic transmission GO:0050804 141 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
axon ensheathment GO:0008366 40 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
cellular response to insulin stimulus GO:0032869 81 0.030
purine containing compound catabolic process GO:0072523 138 0.030
amine metabolic process GO:0009308 38 0.030
cell migration GO:0016477 197 0.029
guanosine containing compound metabolic process GO:1901068 74 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
brain development GO:0007420 247 0.029
vascular process in circulatory system GO:0003018 96 0.029
divalent metal ion transport GO:0070838 132 0.029
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.029
positive regulation of neuron migration GO:2001224 2 0.029
cell part morphogenesis GO:0032990 123 0.029
positive regulation of cellular component organization GO:0051130 200 0.029
Rat
positive regulation of cell differentiation GO:0045597 217 0.028
Rat
positive regulation of developmental process GO:0051094 283 0.028
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.028
female pregnancy GO:0007565 122 0.028
hormone transport GO:0009914 121 0.028
Mouse
regulation of postsynaptic membrane potential GO:0060078 25 0.028
apoptotic process GO:0006915 381 0.028
neuron apoptotic process GO:0051402 88 0.028
negative regulation of metabolic process GO:0009892 331 0.027
positive regulation of nucleotide metabolic process GO:0045981 91 0.027
positive regulation of gene expression GO:0010628 244 0.027
regulation of neuron differentiation GO:0045664 208 0.027
ribonucleotide metabolic process GO:0009259 231 0.027
cell projection morphogenesis GO:0048858 123 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
positive regulation of cell projection organization GO:0031346 111 0.027
Rat
response to insulin GO:0032868 133 0.027
regulation of secretion by cell GO:1903530 208 0.027
Mouse
positive regulation of molecular function GO:0044093 230 0.027
response to estradiol GO:0032355 164 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
Rat
positive regulation of secretion by cell GO:1903532 128 0.027
metal ion homeostasis GO:0055065 186 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
protein complex assembly GO:0006461 263 0.026
peptide secretion GO:0002790 86 0.026
Mouse
positive regulation of rna metabolic process GO:0051254 203 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
mapk cascade GO:0000165 140 0.026
Rat
sensory perception GO:0007600 101 0.026
purine containing compound metabolic process GO:0072521 253 0.026
regulation of anatomical structure size GO:0090066 135 0.026
circulatory system development GO:0072359 134 0.026
stress activated protein kinase signaling cascade GO:0031098 37 0.026
multicellular organismal signaling GO:0035637 44 0.026
cellular macromolecule localization GO:0070727 122 0.025
cellular calcium ion homeostasis GO:0006874 160 0.025
response to corticosteroid GO:0031960 235 0.025
establishment of protein localization GO:0045184 141 0.025
myelination GO:0042552 39 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
negative regulation of cell communication GO:0010648 158 0.025
exocytosis GO:0006887 60 0.025
Mouse
vesicle mediated transport GO:0016192 181 0.025
Mouse
cell motility GO:0048870 202 0.025
cellular component morphogenesis GO:0032989 155 0.025
positive regulation of protein phosphorylation GO:0001934 135 0.024
Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
regulation of apoptotic process GO:0042981 335 0.024
signal transduction by phosphorylation GO:0023014 144 0.024
Rat
organic hydroxy compound transport GO:0015850 77 0.024
carboxylic acid transport GO:0046942 115 0.024
regulation of programmed cell death GO:0043067 341 0.023
response to hypoxia GO:0001666 231 0.023
divalent inorganic cation transport GO:0072511 134 0.023
ensheathment of neurons GO:0007272 40 0.023
response to inorganic substance GO:0010035 377 0.023
regeneration GO:0031099 163 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
positive regulation of cellular component movement GO:0051272 102 0.023
peptide transport GO:0015833 97 0.023
Mouse
positive regulation of neurogenesis GO:0050769 165 0.023
Rat
regulation of rna metabolic process GO:0051252 391 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
positive regulation of homeostatic process GO:0032846 49 0.023
negative regulation of response to stimulus GO:0048585 155 0.022
positive regulation of apoptotic process GO:0043065 154 0.022
negative regulation of rna metabolic process GO:0051253 123 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
Rat
biological adhesion GO:0022610 110 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
response to lipopolysaccharide GO:0032496 191 0.021
response to organophosphorus GO:0046683 102 0.021
regulation of stress activated mapk cascade GO:0032872 23 0.021
response to decreased oxygen levels GO:0036293 237 0.021
negative regulation of gene expression GO:0010629 199 0.021
regulation of phosphorylation GO:0042325 248 0.021
Rat
regulation of protein metabolic process GO:0051246 289 0.021
Rat
macromolecular complex subunit organization GO:0043933 339 0.021
peptide hormone secretion GO:0030072 84 0.021
Mouse
negative regulation of cell death GO:0060548 229 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
Rat
cellular component biogenesis GO:0044085 368 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
maintenance of location GO:0051235 17 0.020
axon development GO:0061564 96 0.020
stress activated mapk cascade GO:0051403 35 0.020
response to estrogen GO:0043627 232 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
inorganic cation transmembrane transport GO:0098662 202 0.020
small molecule biosynthetic process GO:0044283 124 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
response to wounding GO:0009611 254 0.020
amino acid transport GO:0006865 70 0.020
hormone secretion GO:0046879 115 0.020
Mouse
single organism catabolic process GO:0044712 283 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
response to radiation GO:0009314 137 0.019
mesoderm development GO:0007498 2 0.019
regulation of cell motility GO:2000145 131 0.019
regulation of vesicle mediated transport GO:0060627 81 0.019
Mouse
response to amine GO:0014075 46 0.019
monocarboxylic acid metabolic process GO:0032787 152 0.019
circulatory system process GO:0003013 183 0.019
cell type specific apoptotic process GO:0097285 134 0.019
sequestering of metal ion GO:0051238 9 0.019
regulation of peptide transport GO:0090087 87 0.019
positive regulation of cell development GO:0010720 176 0.019
Rat
regulation of locomotion GO:0040012 148 0.019
regulation of dendrite development GO:0050773 59 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
cellular protein localization GO:0034613 122 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
regulation of cellular response to stress GO:0080135 49 0.019
circadian rhythm GO:0007623 88 0.019
glycerolipid metabolic process GO:0046486 67 0.019
regulation of intracellular signal transduction GO:1902531 218 0.018
Mouse Rat
organelle organization GO:0006996 266 0.018
calcium ion transport GO:0006816 131 0.018
response to other organism GO:0051707 220 0.018
regulation of neuron projection development GO:0010975 161 0.018
regulation of cellular component biogenesis GO:0044087 86 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
Rat
negative regulation of secretion GO:0051048 82 0.018
regulation of p38mapk cascade GO:1900744 1 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
positive regulation of peptide secretion GO:0002793 52 0.018
cellular response to alcohol GO:0097306 87 0.018
response to glucocorticoid GO:0051384 223 0.018
organic acid transport GO:0015849 116 0.018
immune system process GO:0002376 204 0.018
ion transmembrane transport GO:0034220 365 0.017
muscle system process GO:0003012 115 0.017
regulation of proteasomal protein catabolic process GO:0061136 4 0.017
regulation of neuron apoptotic process GO:0043523 83 0.017
positive regulation of nucleoside metabolic process GO:0045979 55 0.017
cation homeostasis GO:0055080 195 0.017
cell morphogenesis GO:0000902 142 0.017
regulation of immune system process GO:0002682 123 0.017
calcium ion transmembrane transport GO:0070588 70 0.017
carbohydrate homeostasis GO:0033500 75 0.017
p38mapk cascade GO:0038066 1 0.017
axis specification GO:0009798 4 0.017
response to camp GO:0051591 91 0.016
positive regulation of cell death GO:0010942 184 0.016
cellular response to drug GO:0035690 30 0.016
locomotion GO:0040011 237 0.016
ras protein signal transduction GO:0007265 29 0.016
neuron neuron synaptic transmission GO:0007270 60 0.016
organic anion transport GO:0015711 132 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
negative regulation of cell development GO:0010721 82 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
negative regulation of developmental process GO:0051093 125 0.016
negative regulation of ion transport GO:0043271 51 0.016
regulation of cell migration GO:0030334 128 0.016
fatty acid metabolic process GO:0006631 99 0.016
regulation of mapk cascade GO:0043408 116 0.016
Rat
response to hydrogen peroxide GO:0042542 89 0.016
response to external biotic stimulus GO:0043207 221 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
regulation of metal ion transport GO:0010959 118 0.015
regulation of intracellular transport GO:0032386 65 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
aging GO:0007568 241 0.015
protein phosphorylation GO:0006468 345 0.015
Rat
positive regulation of transferase activity GO:0051347 81 0.015
Rat
single organism cellular localization GO:1902580 102 0.015
gamete generation GO:0007276 124 0.015
insulin like growth factor receptor signaling pathway GO:0048009 3 0.015
positive regulation of nucleotide catabolic process GO:0030813 53 0.015
action potential GO:0001508 54 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
developmental process involved in reproduction GO:0003006 159 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
forebrain development GO:0030900 98 0.015
positive regulation of signaling GO:0023056 270 0.015
Rat
nucleotide metabolic process GO:0009117 279 0.015
positive regulation of dendrite development GO:1900006 35 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
response to vitamin GO:0033273 131 0.015
carbohydrate metabolic process GO:0005975 130 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
nucleocytoplasmic transport GO:0006913 48 0.014
embryonic skeletal system development GO:0048706 3 0.014
cellular ion homeostasis GO:0006873 184 0.014
sequestering of calcium ion GO:0051208 8 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
response to light stimulus GO:0009416 52 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
chemosensory behavior GO:0007635 2 0.014
glucose homeostasis GO:0042593 75 0.014
cellular response to lipid GO:0071396 201 0.014
response to alkaloid GO:0043279 132 0.014
inflammatory response GO:0006954 150 0.014
nucleotide catabolic process GO:0009166 139 0.014
muscle cell proliferation GO:0033002 84 0.014
negative regulation of hormone secretion GO:0046888 46 0.014
positive regulation of protein modification process GO:0031401 142 0.014
Rat
regulation of peptide hormone secretion GO:0090276 80 0.014
regulation of protein modification process GO:0031399 194 0.014
Rat
single organism organelle organization GO:1902589 180 0.014
adult locomotory behavior GO:0008344 4 0.014
regulation of exocytosis GO:0017157 37 0.014
Mouse
calcium ion homeostasis GO:0055074 162 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
cytoplasmic transport GO:0016482 115 0.014
aromatic compound catabolic process GO:0019439 168 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
intracellular transport GO:0046907 185 0.014
receptor mediated endocytosis GO:0006898 42 0.013
heterocycle catabolic process GO:0046700 167 0.013
response to growth factor GO:0070848 189 0.013
Rat
positive regulation of transcription dna templated GO:0045893 197 0.013
gliogenesis GO:0042063 93 0.013
organophosphate catabolic process GO:0046434 148 0.013
positive regulation of neuron death GO:1901216 43 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
response to oxidative stress GO:0006979 186 0.013
response to acid chemical GO:0001101 222 0.013
regulation of jnk cascade GO:0046328 19 0.013
cellular response to glucose stimulus GO:0071333 65 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
cell adhesion GO:0007155 110 0.013
regulation of transporter activity GO:0032409 50 0.013
regulation of establishment of planar polarity GO:0090175 2 0.013
defense response GO:0006952 194 0.013
localization of cell GO:0051674 202 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
regulation of muscle system process GO:0090257 79 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
response to reactive oxygen species GO:0000302 120 0.012
response to mechanical stimulus GO:0009612 134 0.012
axonogenesis GO:0007409 71 0.012
actin filament based process GO:0030029 86 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
response to ethanol GO:0045471 162 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
protein transport GO:0015031 132 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
male gamete generation GO:0048232 99 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
Rat
tissue development GO:0009888 252 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
response to ketone GO:1901654 182 0.012
cellular response to hexose stimulus GO:0071331 65 0.012
morphogenesis of a polarized epithelium GO:0001738 1 0.012
neurotransmitter transport GO:0006836 42 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
telencephalon development GO:0021537 62 0.012
response to bacterium GO:0009617 200 0.012
gastrulation GO:0007369 2 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
single organism intracellular transport GO:1902582 166 0.012
potassium ion transport GO:0006813 97 0.012
cellular response to ketone GO:1901655 51 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
Rat
negative regulation of cellular component organization GO:0051129 83 0.012
insulin secretion GO:0030073 69 0.012
Mouse
response to fatty acid GO:0070542 65 0.012
positive regulation of programmed cell death GO:0043068 157 0.011
lipid catabolic process GO:0016042 46 0.011
regulation of cell growth GO:0001558 85 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
response to increased oxygen levels GO:0036296 45 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
Rat
ribonucleotide catabolic process GO:0009261 136 0.011
hair cell differentiation GO:0035315 2 0.011
regulation of response to external stimulus GO:0032101 106 0.011
olfactory behavior GO:0042048 2 0.011
chromosome segregation GO:0007059 2 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
organ regeneration GO:0031100 101 0.011
regulation of body fluid levels GO:0050878 90 0.011
regulation of carbohydrate catabolic process GO:0043470 14 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
organ morphogenesis GO:0009887 75 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
lipid storage GO:0019915 1 0.011
regulation of protein localization GO:0032880 81 0.011
regulation of ion homeostasis GO:2000021 63 0.011
cell cycle GO:0007049 101 0.011
regulation of calcium ion transport GO:0051924 77 0.011
cellular glucose homeostasis GO:0001678 66 0.011
regulation of growth GO:0040008 105 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
lipid localization GO:0010876 62 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.011
regulation of transferase activity GO:0051338 123 0.011
Rat
spermatogenesis GO:0007283 99 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
response to biotic stimulus GO:0009607 226 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
regulation of transmembrane transport GO:0034762 122 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
macromolecule catabolic process GO:0009057 58 0.011
catecholamine transport GO:0051937 37 0.011
mechanoreceptor differentiation GO:0042490 2 0.010
negative regulation of neuron death GO:1901215 69 0.010
positive regulation of cytoplasmic transport GO:1903651 32 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
bmp signaling pathway GO:0030509 4 0.010
negative regulation of monooxygenase activity GO:0032769 3 0.010
protein oligomerization GO:0051259 191 0.010
lymphocyte homeostasis GO:0002260 2 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
cell activation GO:0001775 97 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
Rat
small gtpase mediated signal transduction GO:0007264 36 0.010

Rapgef4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.071
nervous system disease DOID:863 0 0.071
sensory system disease DOID:0050155 0 0.022
disease of metabolism DOID:0014667 0 0.015
central nervous system disease DOID:331 0 0.015
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.012
inherited metabolic disorder DOID:655 0 0.011