Rattus norvegicus

0 known processes

RatNP-3b

defensin RatNP-3 precursor

(Aliases: NP-3b,NP-3a,Np3,NP-3)

RatNP-3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to estrogen GO:0043627 232 0.404
organic acid transport GO:0015849 116 0.294
monocarboxylic acid transport GO:0015718 52 0.274
immune system process GO:0002376 204 0.217
Human
positive regulation of multicellular organismal process GO:0051240 387 0.162
cytokine production GO:0001816 61 0.134
response to molecule of bacterial origin GO:0002237 194 0.131
regulation of cell proliferation GO:0042127 359 0.115
regulation of multicellular organismal development GO:2000026 376 0.114
response to acid chemical GO:0001101 222 0.112
carboxylic acid transport GO:0046942 115 0.110
regulation of cytokine production GO:0001817 56 0.109
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.107
response to biotic stimulus GO:0009607 226 0.106
Human
single organism biosynthetic process GO:0044711 342 0.104
immune response GO:0006955 104 0.103
Human
cellular amino acid metabolic process GO:0006520 107 0.103
response to extracellular stimulus GO:0009991 380 0.096
multi organism reproductive process GO:0044703 262 0.094
negative regulation of cell death GO:0060548 229 0.088
protein localization GO:0008104 191 0.083
response to glucocorticoid GO:0051384 223 0.081
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.081
response to oxidative stress GO:0006979 186 0.081
cellular response to alcohol GO:0097306 87 0.080
neurological system process GO:0050877 219 0.077
response to peptide GO:1901652 292 0.076
organic anion transport GO:0015711 132 0.075
ribonucleotide biosynthetic process GO:0009260 85 0.075
proteolysis GO:0006508 175 0.075
regulation of blood pressure GO:0008217 83 0.072
regulation of hormone levels GO:0010817 187 0.067
negative regulation of multicellular organismal process GO:0051241 203 0.065
response to oxygen levels GO:0070482 265 0.064
response to estradiol GO:0032355 164 0.063
regulation of cell development GO:0060284 263 0.061
positive regulation of cell migration GO:0030335 96 0.060
response to nutrient levels GO:0031667 370 0.059
purine ribonucleotide biosynthetic process GO:0009152 81 0.058
positive regulation of cell communication GO:0010647 271 0.058
organophosphate biosynthetic process GO:0090407 143 0.058
purine ribonucleotide metabolic process GO:0009150 227 0.055
organic acid metabolic process GO:0006082 292 0.055
purine nucleotide metabolic process GO:0006163 229 0.055
response to cytokine GO:0034097 215 0.054
ribose phosphate metabolic process GO:0019693 235 0.053
macromolecule localization GO:0033036 252 0.053
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.053
regulation of transcription dna templated GO:0006355 374 0.052
regulation of cell differentiation GO:0045595 320 0.052
anion transport GO:0006820 178 0.052
response to corticosteroid GO:0031960 235 0.052
positive regulation of necroptotic process GO:0060545 2 0.052
metal ion transport GO:0030001 289 0.052
defense response GO:0006952 194 0.051
Human
response to peptide hormone GO:0043434 278 0.049
purine containing compound metabolic process GO:0072521 253 0.049
positive regulation of cellular biosynthetic process GO:0031328 295 0.049
positive regulation of catalytic activity GO:0043085 184 0.048
response to bacterium GO:0009617 200 0.048
Human
positive regulation of rna biosynthetic process GO:1902680 197 0.047
cation transport GO:0006812 382 0.047
organonitrogen compound biosynthetic process GO:1901566 167 0.046
cgmp biosynthetic process GO:0006182 15 0.045
regulation of phosphorus metabolic process GO:0051174 349 0.045
regulation of catalytic activity GO:0050790 304 0.045
reproductive process GO:0022414 372 0.045
nitrogen compound transport GO:0071705 229 0.045
regulation of cellular component organization GO:0051128 368 0.045
positive regulation of cytokine production GO:0001819 42 0.044
negative regulation of metabolic process GO:0009892 331 0.044
cyclic purine nucleotide metabolic process GO:0052652 62 0.044
positive regulation of molecular function GO:0044093 230 0.043
innate immune response GO:0045087 35 0.042
Human
intracellular transport GO:0046907 185 0.042
response to monosaccharide GO:0034284 159 0.042
positive regulation of signaling GO:0023056 270 0.041
nucleobase containing small molecule metabolic process GO:0055086 316 0.041
cellular response to glucocorticoid stimulus GO:0071385 68 0.040
regulation of anatomical structure morphogenesis GO:0022603 141 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.040
nucleotide metabolic process GO:0009117 279 0.040
response to other organism GO:0051707 220 0.039
Human
response to glucose GO:0009749 136 0.039
organ regeneration GO:0031100 101 0.039
response to inorganic substance GO:0010035 377 0.039
leukocyte differentiation GO:0002521 30 0.038
ribonucleotide metabolic process GO:0009259 231 0.038
aging GO:0007568 241 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.038
regulation of homeostatic process GO:0032844 101 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.036
carboxylic acid metabolic process GO:0019752 289 0.036
head development GO:0060322 247 0.035
nucleoside phosphate biosynthetic process GO:1901293 102 0.035
acid secretion GO:0046717 48 0.034
organic hydroxy compound transport GO:0015850 77 0.034
regulation of rna metabolic process GO:0051252 391 0.034
transcription from rna polymerase ii promoter GO:0006366 252 0.034
g protein coupled receptor signaling pathway GO:0007186 242 0.033
transcription dna templated GO:0006351 377 0.033
cellular response to oxygen containing compound GO:1901701 386 0.033
regulation of purine nucleotide metabolic process GO:1900542 115 0.033
calcium ion transport GO:0006816 131 0.033
regulation of nucleotide metabolic process GO:0006140 117 0.032
positive regulation of secretion GO:0051047 140 0.032
positive regulation of ion transport GO:0043270 94 0.032
establishment of protein localization GO:0045184 141 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
positive regulation of developmental process GO:0051094 283 0.031
purine containing compound biosynthetic process GO:0072522 85 0.031
regulation of necroptotic process GO:0060544 2 0.031
response to external biotic stimulus GO:0043207 221 0.030
Human
transmembrane transport GO:0055085 412 0.030
carbohydrate derivative biosynthetic process GO:1901137 124 0.030
positive regulation of cell motility GO:2000147 97 0.030
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.030
protein maturation GO:0051604 68 0.030
amine metabolic process GO:0009308 38 0.029
rna metabolic process GO:0016070 406 0.029
cell cell signaling GO:0007267 335 0.029
purine nucleotide biosynthetic process GO:0006164 83 0.029
cellular response to stress GO:0033554 269 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.028
cell projection organization GO:0030030 302 0.028
homeostatic process GO:0042592 331 0.028
positive regulation of protein phosphorylation GO:0001934 135 0.028
neuron differentiation GO:0030182 368 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
lymphocyte activation GO:0046649 43 0.027
ribose phosphate biosynthetic process GO:0046390 87 0.027
divalent inorganic cation transport GO:0072511 134 0.027
neuron death GO:0070997 127 0.027
regeneration GO:0031099 163 0.027
inflammatory response GO:0006954 150 0.027
positive regulation of necrotic cell death GO:0010940 4 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
secretion by cell GO:0032940 248 0.026
positive regulation of nervous system development GO:0051962 178 0.026
regulation of rna biosynthetic process GO:2001141 381 0.026
muscle system process GO:0003012 115 0.026
regulation of ion homeostasis GO:2000021 63 0.026
cellular response to steroid hormone stimulus GO:0071383 93 0.025
nucleotide biosynthetic process GO:0009165 98 0.025
cellular amine metabolic process GO:0044106 38 0.025
oxoacid metabolic process GO:0043436 290 0.025
cellular homeostasis GO:0019725 252 0.025
cellular ketone metabolic process GO:0042180 51 0.025
neuron development GO:0048666 286 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
organic substance catabolic process GO:1901575 316 0.024
amine transport GO:0015837 57 0.024
regulation of molecular function GO:0065009 398 0.024
cellular response to ketone GO:1901655 51 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
positive regulation of secretion by cell GO:1903532 128 0.024
apoptotic process GO:0006915 381 0.024
cyclic nucleotide biosynthetic process GO:0009190 63 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
regulation of ion transport GO:0043269 245 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
female pregnancy GO:0007565 122 0.023
response to ketone GO:1901654 182 0.023
behavior GO:0007610 205 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
positive regulation of organic acid transport GO:0032892 22 0.022
response to wounding GO:0009611 254 0.022
leukocyte cell cell adhesion GO:0007159 4 0.022
response to ethanol GO:0045471 162 0.022
negative regulation of developmental process GO:0051093 125 0.022
cytoplasmic transport GO:0016482 115 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
immune system development GO:0002520 41 0.022
sequestering of metal ion GO:0051238 9 0.021
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.021
response to metal ion GO:0010038 253 0.021
ion homeostasis GO:0050801 212 0.021
necroptotic process GO:0070266 2 0.021
cellular response to lipid GO:0071396 201 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
tissue development GO:0009888 252 0.021
regulation of secretion GO:0051046 224 0.021
circulatory system process GO:0003013 183 0.021
negative regulation of neuron death GO:1901215 69 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
sequestering of calcium ion GO:0051208 8 0.020
cellular amide metabolic process GO:0043603 44 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
regulation of immune response GO:0050776 55 0.020
gamete generation GO:0007276 124 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
synaptic transmission GO:0007268 235 0.020
regulation of nucleotide biosynthetic process GO:0030808 47 0.020
cellular modified amino acid metabolic process GO:0006575 61 0.019
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
rna biosynthetic process GO:0032774 380 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
fatty acid transport GO:0015908 25 0.019
intracellular signal transduction GO:0035556 314 0.019
cyclic nucleotide metabolic process GO:0009187 80 0.019
regulation of immune system process GO:0002682 123 0.019
organophosphate metabolic process GO:0019637 370 0.019
transmission of nerve impulse GO:0019226 42 0.019
regulation of secretion by cell GO:1903530 208 0.019
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.019
amino acid transport GO:0006865 70 0.019
vascular process in circulatory system GO:0003018 96 0.018
camp biosynthetic process GO:0006171 47 0.018
response to decreased oxygen levels GO:0036293 237 0.018
lipid metabolic process GO:0006629 283 0.018
response to carbohydrate GO:0009743 183 0.018
cellular response to reactive oxygen species GO:0034614 55 0.018
mechanoreceptor differentiation GO:0042490 2 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
cellular component biogenesis GO:0044085 368 0.018
response to food GO:0032094 27 0.018
regulation of phosphorylation GO:0042325 248 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
multi multicellular organism process GO:0044706 138 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
positive regulation of cellular component movement GO:0051272 102 0.017
cellular response to oxidative stress GO:0034599 76 0.017
cellular component assembly GO:0022607 360 0.017
steroid metabolic process GO:0008202 73 0.017
learning or memory GO:0007611 90 0.017
lipid transport GO:0006869 61 0.017
cellular hormone metabolic process GO:0034754 49 0.017
cell motility GO:0048870 202 0.017
protein transport GO:0015031 132 0.016
response to growth factor GO:0070848 189 0.016
chemical homeostasis GO:0048878 292 0.016
response to interleukin 1 GO:0070555 55 0.016
hair cell differentiation GO:0035315 2 0.016
regulation of response to stress GO:0080134 126 0.016
regulation of mapk cascade GO:0043408 116 0.016
negative regulation of gene expression GO:0010629 199 0.016
regulation of neurogenesis GO:0050767 247 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.016
localization of cell GO:0051674 202 0.016
regulation of protein localization GO:0032880 81 0.016
secretion GO:0046903 307 0.016
positive regulation of homeostatic process GO:0032846 49 0.015
positive regulation of immunoglobulin production GO:0002639 4 0.015
multicellular organism reproduction GO:0032504 233 0.015
renal system process GO:0003014 40 0.015
action potential GO:0001508 54 0.015
regulation of muscle system process GO:0090257 79 0.015
wound healing GO:0042060 122 0.015
regulation of anatomical structure size GO:0090066 135 0.015
regulation of cellular localization GO:0060341 263 0.015
cellular response to biotic stimulus GO:0071216 59 0.015
regulation of synapse organization GO:0050807 19 0.015
embryonic pattern specification GO:0009880 1 0.015
cellular lipid metabolic process GO:0044255 208 0.015
regulation of response to external stimulus GO:0032101 106 0.015
cytosolic calcium ion transport GO:0060401 39 0.015
response to hexose GO:0009746 144 0.015
dna metabolic process GO:0006259 96 0.015
divalent metal ion transport GO:0070838 132 0.014
regulation of neuron projection development GO:0010975 161 0.014
single organism behavior GO:0044708 130 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
regulation of tube size GO:0035150 89 0.014
embryonic axis specification GO:0000578 1 0.014
regulation of defense response GO:0031347 68 0.014
acute inflammatory response GO:0002526 58 0.014
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.014
small molecule biosynthetic process GO:0044283 124 0.014
axis specification GO:0009798 4 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
catabolic process GO:0009056 351 0.014
cell chemotaxis GO:0060326 31 0.014
tube development GO:0035295 89 0.014
organic hydroxy compound biosynthetic process GO:1901617 51 0.014
response to lipopolysaccharide GO:0032496 191 0.014
regulation of protein modification process GO:0031399 194 0.014
positive regulation of cell death GO:0010942 184 0.013
positive regulation of protein modification process GO:0031401 142 0.013
regulation of neuron differentiation GO:0045664 208 0.013
reproduction GO:0000003 245 0.013
metal ion homeostasis GO:0055065 186 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
norepinephrine secretion GO:0048243 16 0.013
male gamete generation GO:0048232 99 0.013
positive regulation of gene expression GO:0010628 244 0.013
establishment of tissue polarity GO:0007164 2 0.013
single organism catabolic process GO:0044712 283 0.013
biological adhesion GO:0022610 110 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
auditory receptor cell differentiation GO:0042491 2 0.013
hormone metabolic process GO:0042445 69 0.013
brain development GO:0007420 247 0.013
response to fatty acid GO:0070542 65 0.013
single organism cell adhesion GO:0098602 46 0.013
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.013
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
ion transmembrane transport GO:0034220 365 0.012
regulation of synaptic transmission GO:0050804 141 0.012
b cell differentiation GO:0030183 2 0.012
negative regulation of skeletal muscle tissue development GO:0048642 3 0.012
regulation of embryonic development GO:0045995 2 0.012
regulation of cellular component movement GO:0051270 150 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
bile acid and bile salt transport GO:0015721 12 0.012
regulation of protein metabolic process GO:0051246 289 0.012
peptidyl amino acid modification GO:0018193 126 0.012
positive regulation of blood circulation GO:1903524 65 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
inner ear receptor cell differentiation GO:0060113 2 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
regulation of apoptotic process GO:0042981 335 0.012
neuron projection development GO:0031175 273 0.012
regulation of anion transport GO:0044070 43 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
actin filament depolymerization GO:0030042 3 0.012
regulation of organic acid transport GO:0032890 35 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
protein heterooligomerization GO:0051291 89 0.012
cell migration GO:0016477 197 0.012
one carbon compound transport GO:0019755 5 0.012
nucleic acid templated transcription GO:0097659 379 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
regulation of neuron death GO:1901214 115 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
single organismal cell cell adhesion GO:0016337 42 0.012
glycerol transport GO:0015793 2 0.012
spermatogenesis GO:0007283 99 0.012
response to cadmium ion GO:0046686 35 0.011
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.011
appendage morphogenesis GO:0035107 4 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
response to ammonium ion GO:0060359 71 0.011
ras protein signal transduction GO:0007265 29 0.011
single organism intracellular transport GO:1902582 166 0.011
response to muscle stretch GO:0035994 2 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
positive regulation of leukocyte proliferation GO:0070665 20 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
positive regulation of gamma aminobutyric acid secretion GO:0014054 4 0.011
urogenital system development GO:0001655 78 0.011
regulation of membrane potential GO:0042391 110 0.011
ossification GO:0001503 70 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
regulation of body fluid levels GO:0050878 90 0.011
gliogenesis GO:0042063 93 0.011
response to starvation GO:0042594 59 0.011
alcohol biosynthetic process GO:0046165 38 0.011
positive regulation of calcium ion transport GO:0051928 36 0.011
regulation of system process GO:0044057 208 0.011
cation transmembrane transport GO:0098655 263 0.011
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
response to amino acid GO:0043200 75 0.011
regulation of kinase activity GO:0043549 117 0.011
peptide metabolic process GO:0006518 32 0.011
maintenance of location GO:0051235 17 0.011
negative regulation of monooxygenase activity GO:0032769 3 0.011
neuropeptide signaling pathway GO:0007218 29 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
cellular response to peptide GO:1901653 133 0.011
anion transmembrane transport GO:0098656 77 0.011
chemosensory behavior GO:0007635 2 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
hormone secretion GO:0046879 115 0.010
interferon gamma production GO:0032609 3 0.010
rna localization GO:0006403 4 0.010
lipid localization GO:0010876 62 0.010
response to activity GO:0014823 73 0.010
sexual reproduction GO:0019953 148 0.010
positive regulation of transport GO:0051050 245 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
cellular response to dexamethasone stimulus GO:0071549 36 0.010
defense response to other organism GO:0098542 17 0.010
Human
cell type specific apoptotic process GO:0097285 134 0.010
forebrain development GO:0030900 98 0.010
cellular chemical homeostasis GO:0055082 247 0.010
regulation of interferon gamma production GO:0032649 3 0.010
positive regulation of synaptic transmission GO:0050806 62 0.010
chromosome segregation GO:0007059 2 0.010
alcohol metabolic process GO:0006066 77 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010

RatNP-3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
musculoskeletal system disease DOID:17 0 0.029
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.016
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.016
inherited metabolic disorder DOID:655 0 0.015
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
sensory system disease DOID:0050155 0 0.010