Rattus norvegicus

31 known processes

Rdh2

retinol dehydrogenase 2

(Aliases: RoDHII)

Rdh2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 152 0.423
transmembrane transport GO:0055085 412 0.403
lipid metabolic process GO:0006629 283 0.372
oxoacid metabolic process GO:0043436 290 0.356
antibiotic transport GO:0042891 2 0.252
alpha amino acid metabolic process GO:1901605 71 0.248
regulation of nervous system development GO:0051960 264 0.226
carboxylic acid metabolic process GO:0019752 289 0.196
positive regulation of nervous system development GO:0051962 178 0.195
fatty acid metabolic process GO:0006631 99 0.194
cellular component assembly GO:0022607 360 0.185
ion transmembrane transport GO:0034220 365 0.179
glutathione transport GO:0034635 2 0.173
carboxylic acid biosynthetic process GO:0046394 83 0.161
sulfur amino acid metabolic process GO:0000096 9 0.155
choline transport GO:0015871 4 0.146
sulfur compound transport GO:0072348 8 0.142
amide transport GO:0042886 105 0.139
rna metabolic process GO:0016070 406 0.127
anion transmembrane transport GO:0098656 77 0.123
cellular response to endogenous stimulus GO:0071495 377 0.122
neuron development GO:0048666 286 0.116
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.116
single organism biosynthetic process GO:0044711 342 0.114
response to purine containing compound GO:0014074 126 0.112
regulation of neuron differentiation GO:0045664 208 0.107
positive regulation of neurogenesis GO:0050769 165 0.104
organic acid metabolic process GO:0006082 292 0.101
anatomical structure morphogenesis GO:0009653 298 0.094
regulation of neurogenesis GO:0050767 247 0.092
response to molecule of fungal origin GO:0002238 3 0.091
quaternary ammonium group transport GO:0015697 6 0.086
response to osmotic stress GO:0006970 42 0.085
cation transmembrane transport GO:0098655 263 0.083
tripeptide transport GO:0042939 2 0.079
cellular homeostasis GO:0019725 252 0.074
alpha amino acid biosynthetic process GO:1901607 23 0.074
reproductive process GO:0022414 372 0.073
response to inorganic substance GO:0010035 377 0.072
response to acid chemical GO:0001101 222 0.071
single organism catabolic process GO:0044712 283 0.071
regulation of phagocytosis engulfment GO:0060099 4 0.070
regulation of cellular ketone metabolic process GO:0010565 27 0.068
regulation of cell development GO:0060284 263 0.067
macromolecular complex subunit organization GO:0043933 339 0.064
response to nutrient levels GO:0031667 370 0.063
cell projection organization GO:0030030 302 0.063
response to hexose GO:0009746 144 0.063
protein homooligomerization GO:0051260 91 0.062
cellular lipid metabolic process GO:0044255 208 0.061
lipid biosynthetic process GO:0008610 128 0.059
positive regulation of phagocytosis engulfment GO:0060100 4 0.059
response to oxidative stress GO:0006979 186 0.056
organic acid biosynthetic process GO:0016053 83 0.056
dopamine transport GO:0015872 18 0.056
nitrogen compound transport GO:0071705 229 0.054
cation transport GO:0006812 382 0.053
sodium independent organic anion transport GO:0043252 2 0.053
protein complex biogenesis GO:0070271 263 0.053
protein oligomerization GO:0051259 191 0.053
response to organophosphorus GO:0046683 102 0.053
cellular amino acid biosynthetic process GO:0008652 32 0.053
small molecule biosynthetic process GO:0044283 124 0.053
chemical homeostasis GO:0048878 292 0.052
regulation of cellular component organization GO:0051128 368 0.052
response to carbohydrate GO:0009743 183 0.052
g protein coupled receptor signaling pathway GO:0007186 242 0.050
organic acid transport GO:0015849 116 0.049
positive regulation of neuron differentiation GO:0045666 126 0.049
hormone transport GO:0009914 121 0.048
cellular divalent inorganic cation homeostasis GO:0072503 162 0.048
regulation of secretion by cell GO:1903530 208 0.047
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.046
single organism behavior GO:0044708 130 0.046
rna biosynthetic process GO:0032774 380 0.046
neuron differentiation GO:0030182 368 0.046
regulation of neuron projection development GO:0010975 161 0.046
positive regulation of phosphate metabolic process GO:0045937 262 0.046
ion homeostasis GO:0050801 212 0.046
locomotion GO:0040011 237 0.045
cellular response to stress GO:0033554 269 0.045
toxin transport GO:1901998 3 0.045
cellular component biogenesis GO:0044085 368 0.045
peptide transport GO:0015833 97 0.044
protein complex assembly GO:0006461 263 0.043
protein complex subunit organization GO:0071822 302 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.043
regulation of cell projection organization GO:0031344 175 0.043
positive regulation of gene expression GO:0010628 244 0.042
macromolecular complex assembly GO:0065003 273 0.042
nucleic acid templated transcription GO:0097659 379 0.042
positive regulation of cell communication GO:0010647 271 0.042
positive regulation of signaling GO:0023056 270 0.041
positive regulation of cell migration GO:0030335 96 0.041
cellular ketone metabolic process GO:0042180 51 0.041
organic hydroxy compound metabolic process GO:1901615 115 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.041
organic anion transport GO:0015711 132 0.041
response to monosaccharide GO:0034284 159 0.041
positive regulation of cell motility GO:2000147 97 0.040
growth GO:0040007 165 0.040
cellular response to oxygen containing compound GO:1901701 386 0.039
embryo implantation GO:0007566 15 0.039
fatty acid oxidation GO:0019395 29 0.039
cell motility GO:0048870 202 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
cognition GO:0050890 92 0.039
response to glucose GO:0009749 136 0.038
regulation of locomotion GO:0040012 148 0.038
multi multicellular organism process GO:0044706 138 0.038
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
regulation of cell differentiation GO:0045595 320 0.037
positive regulation of neuron projection development GO:0010976 99 0.037
regulation of anatomical structure size GO:0090066 135 0.036
vitamin d receptor signaling pathway GO:0070561 1 0.036
inorganic ion transmembrane transport GO:0098660 229 0.036
lipid oxidation GO:0034440 30 0.036
amino acid transport GO:0006865 70 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.035
carnitine transport GO:0015879 1 0.035
positive regulation of rna metabolic process GO:0051254 203 0.035
circadian rhythm GO:0007623 88 0.034
anion transport GO:0006820 178 0.034
oligopeptide transport GO:0006857 4 0.034
negative regulation of metabolic process GO:0009892 331 0.034
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.034
drug catabolic process GO:0042737 1 0.034
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
cellular response to nitrogen compound GO:1901699 210 0.033
cellular chemical homeostasis GO:0055082 247 0.033
homeostatic process GO:0042592 331 0.033
positive regulation of locomotion GO:0040017 102 0.033
multicellular organism reproduction GO:0032504 233 0.032
protein heterooligomerization GO:0051291 89 0.032
multicellular organismal reproductive process GO:0048609 233 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
transcription dna templated GO:0006351 377 0.031
metal ion homeostasis GO:0055065 186 0.031
cation homeostasis GO:0055080 195 0.031
muscle cell migration GO:0014812 36 0.031
oxidation reduction process GO:0055114 304 0.031
regulation of transcription dna templated GO:0006355 374 0.030
blood circulation GO:0008015 183 0.030
regulation of transferase activity GO:0051338 123 0.029
positive regulation of phosphorus metabolic process GO:0010562 262 0.029
cellular ion homeostasis GO:0006873 184 0.029
amino acid betaine transport GO:0015838 1 0.029
regulation of catalytic activity GO:0050790 304 0.029
cellular response to organonitrogen compound GO:0071417 197 0.028
positive regulation of hexokinase activity GO:1903301 3 0.028
carboxylic acid transport GO:0046942 115 0.028
central nervous system development GO:0007417 311 0.028
positive regulation of nucleic acid templated transcription GO:1903508 197 0.028
response to oxygen levels GO:0070482 265 0.028
response to transition metal nanoparticle GO:1990267 122 0.028
organonitrogen compound biosynthetic process GO:1901566 167 0.028
regulation of molecular function GO:0065009 398 0.027
cellular cation homeostasis GO:0030003 180 0.027
multicellular organismal signaling GO:0035637 44 0.027
regulation of protein metabolic process GO:0051246 289 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
calcium ion homeostasis GO:0055074 162 0.027
catabolic process GO:0009056 351 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
behavior GO:0007610 205 0.026
positive regulation of cellular component movement GO:0051272 102 0.026
response to starvation GO:0042594 59 0.026
cellular response to organic cyclic compound GO:0071407 202 0.026
response to peptide GO:1901652 292 0.026
secretion GO:0046903 307 0.026
regeneration GO:0031099 163 0.025
vitamin a metabolic process GO:0006776 2 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
response to extracellular stimulus GO:0009991 380 0.025
vascular process in circulatory system GO:0003018 96 0.024
positive regulation of cell projection organization GO:0031346 111 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
monoamine transport GO:0015844 43 0.024
peptide hormone secretion GO:0030072 84 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
synaptic transmission GO:0007268 235 0.024
acute inflammatory response GO:0002526 58 0.023
neuron projection development GO:0031175 273 0.023
sterol catabolic process GO:0016127 1 0.023
isoprenoid metabolic process GO:0006720 45 0.023
cell migration GO:0016477 197 0.022
carbohydrate phosphorylation GO:0046835 16 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
salivary gland development GO:0007431 3 0.022
gamma aminobutyric acid secretion GO:0014051 6 0.022
response to ammonium ion GO:0060359 71 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
neurological system process GO:0050877 219 0.022
neuron death GO:0070997 127 0.022
digestive system development GO:0055123 41 0.022
regulation of insulin secretion GO:0050796 65 0.022
regulation of cell migration GO:0030334 128 0.022
vesicle mediated transport GO:0016192 181 0.021
regulation of signal transduction GO:0009966 318 0.021
multi organism reproductive process GO:0044703 262 0.021
positive regulation of cell development GO:0010720 176 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
monocarboxylic acid transport GO:0015718 52 0.020
organic substance catabolic process GO:1901575 316 0.020
regulation of smooth muscle cell proliferation GO:0048660 75 0.020
cell part morphogenesis GO:0032990 123 0.020
mrna transcription GO:0009299 2 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
dna metabolic process GO:0006259 96 0.020
learning or memory GO:0007611 90 0.020
reproduction GO:0000003 245 0.019
gastrulation GO:0007369 2 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
smooth muscle cell migration GO:0014909 36 0.019
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.019
intracellular signal transduction GO:0035556 314 0.019
cytoskeleton organization GO:0007010 111 0.019
circadian behavior GO:0048512 24 0.019
reactive oxygen species metabolic process GO:0072593 37 0.018
response to camp GO:0051591 91 0.018
small molecule catabolic process GO:0044282 59 0.018
protein phosphorylation GO:0006468 345 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
regulation of neuron death GO:1901214 115 0.018
response to hypoxia GO:0001666 231 0.018
coenzyme metabolic process GO:0006732 86 0.018
response to metal ion GO:0010038 253 0.018
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.018
cell morphogenesis GO:0000902 142 0.018
cellular component movement GO:0006928 248 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
alcohol metabolic process GO:0006066 77 0.018
cellular catabolic process GO:0044248 295 0.017
organelle organization GO:0006996 266 0.017
sterol homeostasis GO:0055092 3 0.017
lipid storage GO:0019915 1 0.017
positive regulation of molecular function GO:0044093 230 0.017
regulation of cell morphogenesis GO:0022604 77 0.017
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.017
peptide secretion GO:0002790 86 0.017
response to amine GO:0014075 46 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
response to light stimulus GO:0009416 52 0.017
insulin secretion GO:0030073 69 0.017
grooming behavior GO:0007625 4 0.017
carboxylic acid catabolic process GO:0046395 49 0.017
regulation of phosphorylation GO:0042325 248 0.016
response to toxic substance GO:0009636 133 0.016
rhythmic behavior GO:0007622 24 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
multicellular organism growth GO:0035264 1 0.016
behavioral response to nicotine GO:0035095 2 0.016
regulation of kinase activity GO:0043549 117 0.016
cell projection morphogenesis GO:0048858 123 0.016
regulation of smooth muscle cell migration GO:0014910 36 0.016
memory GO:0007613 54 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
cell cell signaling GO:0007267 335 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
organic cation transport GO:0015695 11 0.015
amine metabolic process GO:0009308 38 0.015
brain development GO:0007420 247 0.015
negative regulation of signaling GO:0023057 157 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
hepatocyte growth factor receptor signaling pathway GO:0048012 1 0.015
regulation of dendrite development GO:0050773 59 0.015
regulation of cell motility GO:2000145 131 0.015
localization of cell GO:0051674 202 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
regulation of map kinase activity GO:0043405 53 0.014
amino acid transmembrane transport GO:0003333 33 0.014
response to hydrogen peroxide GO:0042542 89 0.014
pancreatic stellate cell proliferation GO:0072343 2 0.014
regulation of hormone secretion GO:0046883 106 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
cellular amine metabolic process GO:0044106 38 0.014
positive regulation of developmental process GO:0051094 283 0.014
single organism organelle organization GO:1902589 180 0.014
secretion by cell GO:0032940 248 0.014
cellular response to vitamin e GO:0071306 3 0.014
neuron projection morphogenesis GO:0048812 122 0.014
regulation of actin cytoskeleton organization GO:0032956 30 0.014
response to growth factor GO:0070848 189 0.014
cellular carbohydrate metabolic process GO:0044262 72 0.014
tissue remodeling GO:0048771 40 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
activation of protein kinase activity GO:0032147 47 0.013
metal ion transport GO:0030001 289 0.013
developmental process involved in reproduction GO:0003006 159 0.013
negative regulation of signal transduction GO:0009968 83 0.013
adult locomotory behavior GO:0008344 4 0.013
response to cytokine GO:0034097 215 0.013
sexual reproduction GO:0019953 148 0.013
response to ketone GO:1901654 182 0.013
regulation of blood circulation GO:1903522 110 0.013
tissue development GO:0009888 252 0.013
gliogenesis GO:0042063 93 0.013
heart development GO:0007507 72 0.013
positive regulation of insulin secretion GO:0032024 36 0.013
intracellular transport GO:0046907 185 0.013
regulation of rna metabolic process GO:0051252 391 0.013
olfactory learning GO:0008355 1 0.013
single organism reproductive process GO:0044702 297 0.013
bmp signaling pathway GO:0030509 4 0.013
cellular response to acid chemical GO:0071229 75 0.013
response to glucocorticoid GO:0051384 223 0.013
maintenance of location GO:0051235 17 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
actin cytoskeleton organization GO:0030036 73 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
single organism intracellular transport GO:1902582 166 0.013
regulation of peptide transport GO:0090087 87 0.013
female pregnancy GO:0007565 122 0.012
cholesterol homeostasis GO:0042632 3 0.012
digestive tract development GO:0048565 39 0.012
response to decreased oxygen levels GO:0036293 237 0.012
modified amino acid transport GO:0072337 12 0.012
regulation of system process GO:0044057 208 0.012
locomotor rhythm GO:0045475 1 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
positive regulation of dendrite development GO:1900006 35 0.012
muscle cell proliferation GO:0033002 84 0.012
negative regulation of cell communication GO:0010648 158 0.012
l glutamate import GO:0051938 2 0.012
dendritic spine organization GO:0097061 12 0.012
drug transport GO:0015893 18 0.012
acidic amino acid transport GO:0015800 10 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
response to peptide hormone GO:0043434 278 0.012
pyruvate metabolic process GO:0006090 27 0.011
dendrite development GO:0016358 72 0.011
response to corticosteroid GO:0031960 235 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
rhythmic process GO:0048511 156 0.011
regulation of peptide secretion GO:0002791 82 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
circulatory system process GO:0003013 183 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
response to calcium ion GO:0051592 59 0.011
response to metformin GO:1901558 1 0.011
response to nutrient GO:0007584 248 0.011
dna replication GO:0006260 37 0.011
regulation of cellular localization GO:0060341 263 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
response to fatty acid GO:0070542 65 0.011
regulation of carbohydrate metabolic process GO:0006109 41 0.011
organophosphate metabolic process GO:0019637 370 0.011
sensory organ development GO:0007423 74 0.011
male gamete generation GO:0048232 99 0.011
transmission of nerve impulse GO:0019226 42 0.011
negative regulation of cell death GO:0060548 229 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
epinephrine transport GO:0048241 7 0.011
negative regulation of gene expression GO:0010629 199 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
regulation of dna metabolic process GO:0051052 60 0.011
signal release GO:0023061 145 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
positive regulation of amine transport GO:0051954 26 0.011
response to radiation GO:0009314 137 0.010
chemosensory behavior GO:0007635 2 0.010
olfactory behavior GO:0042048 2 0.010
regulation of cytoskeleton organization GO:0051493 49 0.010
sodium ion transmembrane transport GO:0035725 67 0.010
negative regulation of collagen biosynthetic process GO:0032966 4 0.010
developmental growth GO:0048589 100 0.010
startle response GO:0001964 2 0.010
myelination GO:0042552 39 0.010
cellular modified amino acid metabolic process GO:0006575 61 0.010
cellular response to ketone GO:1901655 51 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010

Rdh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.034
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
inherited metabolic disorder DOID:655 0 0.018
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
central nervous system disease DOID:331 0 0.014