|
|
mapk cascade
|
GO:0000165 |
140 |
0.451
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.315
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.306
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.287
|
Mouse |
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.257
|
Mouse |
|
|
blood circulation
|
GO:0008015 |
183 |
0.244
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.211
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.190
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.183
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.178
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.172
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.169
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.163
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.162
|
Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.161
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.161
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.159
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.154
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.153
|
|
|
|
blood vessel development
|
GO:0001568 |
69 |
0.149
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.147
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.147
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.141
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.139
|
|
|
|
response to insulin
|
GO:0032868 |
133 |
0.130
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
89 |
0.125
|
|
|
|
response to oxidative stress
|
GO:0006979 |
186 |
0.125
|
|
|
|
anion transport
|
GO:0006820 |
178 |
0.124
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.122
|
Mouse |
|
|
n methyl d aspartate receptor clustering
|
GO:0097114 |
2 |
0.121
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.117
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
48 |
0.115
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
62 |
0.115
|
Mouse |
|
|
circulatory system process
|
GO:0003013 |
183 |
0.114
|
Fly |
|
|
response to ketone
|
GO:1901654 |
182 |
0.113
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.112
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.112
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
77 |
0.111
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.111
|
|
|
|
response to mineralocorticoid
|
GO:0051385 |
49 |
0.110
|
|
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.110
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.108
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
110 |
0.107
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.104
|
|
|
|
neuromuscular process
|
GO:0050905 |
2 |
0.103
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.100
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.099
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.098
|
Mouse |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
52 |
0.098
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.097
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.097
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.091
|
Fly |
|
|
amino acid transport
|
GO:0006865 |
70 |
0.091
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.091
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.090
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
54 |
0.090
|
|
|
|
secretion by tissue
|
GO:0032941 |
37 |
0.090
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.085
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.085
|
|
|
|
feeding behavior
|
GO:0007631 |
53 |
0.084
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.084
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.084
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
84 |
0.082
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
83 |
0.081
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.080
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.079
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.079
|
|
|
|
urinary tract smooth muscle contraction
|
GO:0014848 |
4 |
0.078
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.077
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
33 |
0.074
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.073
|
|
|
|
cell activation
|
GO:0001775 |
97 |
0.073
|
|
|
|
regulation of saliva secretion
|
GO:0046877 |
3 |
0.073
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
37 |
0.073
|
|
|
|
positive regulation of membrane potential
|
GO:0045838 |
16 |
0.071
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.070
|
|
|
|
regulation of amine transport
|
GO:0051952 |
54 |
0.070
|
|
|
|
organic acid transport
|
GO:0015849 |
116 |
0.066
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.066
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.066
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.066
|
Mouse |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.065
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.064
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.064
|
Mouse |
|
|
lipid biosynthetic process
|
GO:0008610 |
128 |
0.063
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
26 |
0.063
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.062
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.062
|
|
|
|
estrous cycle phase
|
GO:0060206 |
15 |
0.062
|
|
|
|
cell growth
|
GO:0016049 |
104 |
0.061
|
|
|
|
regulation of anion transport
|
GO:0044070 |
43 |
0.061
|
|
|
|
regulation of vascular smooth muscle contraction
|
GO:0003056 |
3 |
0.060
|
|
|
|
learning
|
GO:0007612 |
33 |
0.060
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.059
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
25 |
0.059
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.059
|
Fly |
|
|
regulation of body fluid levels
|
GO:0050878 |
90 |
0.059
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.059
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.058
|
Mouse |
|
|
neurotransmitter gated ion channel clustering
|
GO:0072578 |
3 |
0.057
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
65 |
0.057
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.057
|
Mouse |
|
|
regulation of organic acid transport
|
GO:0032890 |
35 |
0.057
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.057
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.057
|
|
|
|
positive regulation of saliva secretion
|
GO:0046878 |
3 |
0.056
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.056
|
Mouse |
|
|
regulation of systemic arterial blood pressure by norepinephrine epinephrine
|
GO:0001993 |
2 |
0.056
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.055
|
Mouse |
|
|
neurological system process
|
GO:0050877 |
219 |
0.055
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.054
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.054
|
|
|
|
muscle contraction
|
GO:0006936 |
88 |
0.054
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.054
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.053
|
|
|
|
leukocyte migration
|
GO:0050900 |
38 |
0.053
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.053
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
46 |
0.053
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
29 |
0.052
|
|
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.052
|
|
|
|
positive regulation of muscle contraction
|
GO:0045933 |
22 |
0.051
|
|
|
|
regulation of amino acid transport
|
GO:0051955 |
25 |
0.050
|
|
|
|
amine transport
|
GO:0015837 |
57 |
0.050
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.050
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.049
|
Fly |
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.049
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
11 |
0.049
|
|
|
|
urinary bladder smooth muscle contraction
|
GO:0014832 |
4 |
0.049
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.049
|
|
|
|
regulation of behavior
|
GO:0050795 |
61 |
0.048
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.048
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.048
|
Human Mouse Fly |
|
|
negative regulation of blood pressure
|
GO:0045776 |
29 |
0.047
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.046
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.046
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.045
|
Mouse |
|
|
saliva secretion
|
GO:0046541 |
3 |
0.045
|
|
|
|
sodium ion transport
|
GO:0006814 |
82 |
0.045
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.043
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.043
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.042
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
60 |
0.042
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.041
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
3 |
0.041
|
|
|
|
regulation of tube size
|
GO:0035150 |
89 |
0.041
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
122 |
0.041
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
51 |
0.041
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.040
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.040
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.040
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.040
|
|
|
|
aging
|
GO:0007568 |
241 |
0.040
|
|
|
|
tissue remodeling
|
GO:0048771 |
40 |
0.040
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.040
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
96 |
0.040
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.040
|
|
|
|
body fluid secretion
|
GO:0007589 |
41 |
0.040
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.040
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
37 |
0.040
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.039
|
Mouse |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.039
|
|
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.039
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.039
|
|
|
|
vasculature development
|
GO:0001944 |
70 |
0.039
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
45 |
0.039
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.039
|
Mouse |
|
|
dicarboxylic acid transport
|
GO:0006835 |
34 |
0.039
|
|
|
|
negative regulation of immune response to tumor cell
|
GO:0002838 |
2 |
0.038
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.038
|
|
|
|
uterine smooth muscle contraction
|
GO:0070471 |
10 |
0.038
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.038
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.038
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
66 |
0.038
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.038
|
|
|
|
regulation of odontogenesis of dentin containing tooth
|
GO:0042487 |
2 |
0.038
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
85 |
0.038
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.037
|
Fly |
|
|
synaptic transmission gabaergic
|
GO:0051932 |
22 |
0.037
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
115 |
0.037
|
|
|
|
growth
|
GO:0040007 |
165 |
0.037
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
5 |
0.036
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
53 |
0.036
|
Mouse |
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.036
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.036
|
Mouse |
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.036
|
Fly |
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.036
|
Human Mouse |
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.036
|
Human Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
42 |
0.036
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.036
|
Fly |
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.035
|
|
|
|
regulation of cell activation
|
GO:0050865 |
50 |
0.035
|
|
|
|
chemosensory behavior
|
GO:0007635 |
2 |
0.035
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.035
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
1 |
0.035
|
|
|
|
heart process
|
GO:0003015 |
57 |
0.035
|
Fly |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.034
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.034
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.034
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.034
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
4 |
0.034
|
|
|
|
positive regulation of blood pressure by epinephrine norepinephrine
|
GO:0003321 |
2 |
0.034
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
59 |
0.034
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
60 |
0.033
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.033
|
|
|
|
positive regulation of growth
|
GO:0045927 |
55 |
0.033
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.032
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.032
|
|
|
|
muscle structure development
|
GO:0061061 |
87 |
0.032
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
1 |
0.032
|
|
|
|
response to estrogen
|
GO:0043627 |
232 |
0.032
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.032
|
Fly |
|
|
regulation of glutamate secretion
|
GO:0014048 |
17 |
0.032
|
|
|
|
membrane depolarization
|
GO:0051899 |
32 |
0.032
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.032
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.031
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
77 |
0.031
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.031
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.031
|
|
|
|
negative regulation of amine transport
|
GO:0051953 |
24 |
0.031
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.031
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
18 |
0.031
|
|
|
|
organic anion transport
|
GO:0015711 |
132 |
0.030
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.030
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
70 |
0.030
|
Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.030
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.030
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.030
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.030
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.030
|
|
|
|
lymphocyte activation
|
GO:0046649 |
43 |
0.029
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.029
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
81 |
0.029
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
25 |
0.029
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
24 |
0.029
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.029
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.029
|
Mouse |
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.029
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.028
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
48 |
0.028
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
46 |
0.028
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.028
|
Mouse |
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
75 |
0.028
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
107 |
0.028
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.027
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.027
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.027
|
|
|
|
activation of protein kinase b activity
|
GO:0032148 |
3 |
0.027
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
1 |
0.027
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.027
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.027
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.027
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.027
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
69 |
0.027
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.027
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.026
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.026
|
|
|
|
leukocyte activation
|
GO:0045321 |
76 |
0.026
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
41 |
0.026
|
|
|
|
adrenergic receptor signaling pathway
|
GO:0071875 |
9 |
0.026
|
|
|
|
dna metabolic process
|
GO:0006259 |
96 |
0.026
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
127 |
0.026
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.026
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.026
|
|
|
|
tonic smooth muscle contraction
|
GO:0014820 |
4 |
0.025
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.025
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
77 |
0.025
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.025
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.025
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
64 |
0.025
|
Mouse |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.025
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.025
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.025
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
77 |
0.025
|
|
|
|
developmental growth
|
GO:0048589 |
100 |
0.024
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.024
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.024
|
|
|
|
renal system process
|
GO:0003014 |
40 |
0.024
|
|
|
|
angiotensin mediated drinking behavior
|
GO:0003051 |
2 |
0.024
|
|
|
|
epithelial cell migration
|
GO:0010631 |
19 |
0.024
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.024
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.024
|
|
|
|
response to corticosterone
|
GO:0051412 |
40 |
0.024
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.024
|
|
|
|
cognition
|
GO:0050890 |
92 |
0.024
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.024
|
|
|
|
gliogenesis
|
GO:0042063 |
93 |
0.024
|
Fly |
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
26 |
0.024
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.024
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.024
|
Fly |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
83 |
0.024
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.024
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.024
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.024
|
Fly |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.023
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.023
|
|
|
|
eating behavior
|
GO:0042755 |
21 |
0.023
|
|
|
|
response to electrical stimulus
|
GO:0051602 |
56 |
0.023
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
91 |
0.023
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.023
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.023
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.022
|
|
|
|
memory
|
GO:0007613 |
54 |
0.022
|
Mouse |
|
|
dopamine secretion
|
GO:0014046 |
15 |
0.022
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.022
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.022
|
|
|
|
atp metabolic process
|
GO:0046034 |
72 |
0.022
|
|
|
|
regulation of ossification
|
GO:0030278 |
32 |
0.022
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.022
|
Fly |
|
|
regulation of vasoconstriction
|
GO:0019229 |
44 |
0.022
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
51 |
0.022
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.022
|
|
|
|
negative regulation of rna splicing
|
GO:0033119 |
3 |
0.022
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
42 |
0.022
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.022
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
37 |
0.022
|
|
|
|
learning or memory
|
GO:0007611 |
90 |
0.022
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
49 |
0.021
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
79 |
0.021
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.021
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.021
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.021
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
120 |
0.021
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.021
|
|
|
|
regulation of cell growth
|
GO:0001558 |
85 |
0.021
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
85 |
0.021
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
4 |
0.021
|
|
|
|
regulation of protein transport
|
GO:0051223 |
68 |
0.021
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.021
|
|
|
|
sensory perception of pain
|
GO:0019233 |
73 |
0.021
|
|
|
|
sex differentiation
|
GO:0007548 |
113 |
0.021
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.021
|
Mouse |
|
|
cellular response to external stimulus
|
GO:0071496 |
118 |
0.021
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
98 |
0.021
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.021
|
Fly |
|
|
membrane depolarization during action potential
|
GO:0086010 |
1 |
0.020
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.020
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.020
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
51 |
0.020
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
39 |
0.020
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.020
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.020
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.020
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
102 |
0.020
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.020
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.020
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.020
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
1 |
0.020
|
|
|
|
endocytosis
|
GO:0006897 |
84 |
0.020
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.020
|
|
|
|
regeneration
|
GO:0031099 |
163 |
0.020
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
55 |
0.020
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
46 |
0.020
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
21 |
0.020
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.020
|
|
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.019
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
161 |
0.019
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
29 |
0.019
|
|
|
|
protein secretion
|
GO:0009306 |
34 |
0.019
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
48 |
0.019
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
49 |
0.019
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
60 |
0.019
|
|
|
|
positive regulation of synaptic transmission glutamatergic
|
GO:0051968 |
13 |
0.019
|
|
|
|
renal sodium excretion
|
GO:0035812 |
20 |
0.019
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.019
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.019
|
|
|
|
positive regulation of heart contraction
|
GO:0045823 |
15 |
0.019
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
63 |
0.019
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.019
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.018
|
|
|
|
sodium ion homeostasis
|
GO:0055078 |
23 |
0.018
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.018
|
|
|
|
negative regulation of response to tumor cell
|
GO:0002835 |
2 |
0.018
|
|
|
|
regulation of organ growth
|
GO:0046620 |
13 |
0.018
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.018
|
|
|
|
response to heat
|
GO:0009408 |
60 |
0.018
|
Fly |
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.018
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
89 |
0.018
|
|
|
|
detection of temperature stimulus involved in sensory perception of pain
|
GO:0050965 |
4 |
0.018
|
|
|
|
synapse assembly
|
GO:0007416 |
29 |
0.018
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
94 |
0.018
|
Fly |
|
|
neuron death
|
GO:0070997 |
127 |
0.018
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
35 |
0.018
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.018
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
38 |
0.018
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.018
|
Mouse |
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.018
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
106 |
0.018
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.018
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
46 |
0.018
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.017
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
99 |
0.017
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.017
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
55 |
0.017
|
|
|
|
positive regulation of smooth muscle contraction
|
GO:0045987 |
18 |
0.017
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.017
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
111 |
0.017
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
81 |
0.017
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
82 |
0.017
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
44 |
0.017
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
93 |
0.017
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
51 |
0.017
|
|
|
|
positive regulation of renin secretion into blood stream
|
GO:1900135 |
1 |
0.017
|
|
|
|
head development
|
GO:0060322 |
247 |
0.017
|
|
|
|
synapse organization
|
GO:0050808 |
46 |
0.017
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.017
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.017
|
|
|
|
heart contraction
|
GO:0060047 |
57 |
0.017
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.017
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
45 |
0.017
|
|
|
|
positive regulation of synaptic transmission gabaergic
|
GO:0032230 |
9 |
0.017
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
62 |
0.017
|
|
|
|
female pregnancy
|
GO:0007565 |
122 |
0.016
|
|
|
|
glutamate secretion
|
GO:0014047 |
19 |
0.016
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.016
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
4 |
0.016
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
25 |
0.016
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.016
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
45 |
0.016
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.016
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.016
|
|
|
|
regulation of vasodilation
|
GO:0042312 |
36 |
0.016
|
|
|
|
vasoconstriction
|
GO:0042310 |
54 |
0.016
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.016
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
44 |
0.016
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
88 |
0.016
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
41 |
0.016
|
|
|
|
regulation of nitric oxide synthase activity
|
GO:0050999 |
8 |
0.016
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
29 |
0.016
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.016
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
42 |
0.016
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.016
|
|
|
|
ionotropic glutamate receptor signaling pathway
|
GO:0035235 |
34 |
0.016
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.016
|
Mouse |
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
84 |
0.016
|
|
|
|
olfactory behavior
|
GO:0042048 |
2 |
0.016
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
31 |
0.016
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
69 |
0.015
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
55 |
0.015
|
|
|
|
response to amphetamine
|
GO:0001975 |
25 |
0.015
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.015
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.015
|
|
|
|
regulation of renal sodium excretion
|
GO:0035813 |
20 |
0.015
|
|
|
|
axon development
|
GO:0061564 |
96 |
0.015
|
|
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
5 |
0.015
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.015
|
|
|
|
diaphragm contraction
|
GO:0002086 |
2 |
0.015
|
|
|
|
monoamine transport
|
GO:0015844 |
43 |
0.015
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.015
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
84 |
0.015
|
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
2 |
0.015
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
49 |
0.015
|
|
|
|
regulation of action potential
|
GO:0098900 |
14 |
0.015
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
126 |
0.015
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.015
|
|
|
|
amide transport
|
GO:0042886 |
105 |
0.015
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.015
|
|
|
|
intracellular protein transport
|
GO:0006886 |
79 |
0.015
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.014
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.014
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.014
|
|
|
|
regulation of cell size
|
GO:0008361 |
37 |
0.014
|
|
|
|
positive regulation of renal sodium excretion
|
GO:0035815 |
10 |
0.014
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
71 |
0.014
|
Fly |
|
|
response to cocaine
|
GO:0042220 |
39 |
0.014
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.014
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.014
|
Fly |
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.014
|
|
|
|
negative regulation of organic acid transport
|
GO:0032891 |
14 |
0.014
|
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
29 |
0.014
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.014
|
|
|
|
gonad development
|
GO:0008406 |
104 |
0.014
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.014
|
|
|
|
single organism behavior
|
GO:0044708 |
130 |
0.014
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.014
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
58 |
0.014
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
83 |
0.014
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.014
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.014
|
Mouse |
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.014
|
Fly |
|
|
inflammatory response
|
GO:0006954 |
150 |
0.014
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
2 |
0.013
|
|
|
|
dephosphorylation
|
GO:0016311 |
98 |
0.013
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
48 |
0.013
|
|
|
|
involuntary skeletal muscle contraction
|
GO:0003011 |
2 |
0.013
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
4 |
0.013
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.013
|
Fly |
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.013
|
Human Mouse Fly |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.013
|
|
|
|
ventral spinal cord interneuron specification
|
GO:0021521 |
2 |
0.013
|
|
|
|
platelet aggregation
|
GO:0070527 |
4 |
0.013
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
78 |
0.013
|
|
|
|
biological phase
|
GO:0044848 |
17 |
0.013
|
|
|
|
presynaptic membrane assembly
|
GO:0097105 |
3 |
0.013
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
47 |
0.013
|
|
|
|
muscle cell migration
|
GO:0014812 |
36 |
0.013
|
|
|
|
triglyceride homeostasis
|
GO:0070328 |
2 |
0.013
|
|
