Rattus norvegicus

75 known processes

Robo1

roundabout homolog 1 (Drosophila)

Robo1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell motility GO:0048870 202 0.740
Human Zebrafish Fly
cell morphogenesis GO:0000902 142 0.692
neuron projection development GO:0031175 273 0.681
axon guidance GO:0007411 24 0.584
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.574
cell part morphogenesis GO:0032990 123 0.559
rna metabolic process GO:0016070 406 0.555
axon midline choice point recognition GO:0016199 2 0.529
axon choice point recognition GO:0016198 2 0.526
regulation of rna biosynthetic process GO:2001141 381 0.486
anatomical structure morphogenesis GO:0009653 298 0.483
neuron apoptotic process GO:0051402 88 0.475
regulation of multicellular organismal development GO:2000026 376 0.466
regulation of nucleic acid templated transcription GO:1903506 380 0.425
central nervous system development GO:0007417 311 0.416
growth GO:0040007 165 0.411
Mouse
tissue development GO:0009888 252 0.402
Human Zebrafish Mouse Fly
heart morphogenesis GO:0003007 3 0.392
Zebrafish Fly
developmental growth GO:0048589 100 0.389
Mouse
programmed cell death GO:0012501 392 0.387
Human
regulation of cellular component organization GO:0051128 368 0.371
regulation of cell differentiation GO:0045595 320 0.364
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.363
regulation of transcription dna templated GO:0006355 374 0.360
cellular component movement GO:0006928 248 0.355
neuron differentiation GO:0030182 368 0.353
cell type specific apoptotic process GO:0097285 134 0.344
regulation of cellular protein metabolic process GO:0032268 267 0.340
Human
transcription from rna polymerase ii promoter GO:0006366 252 0.336
cell migration GO:0016477 197 0.333
Human Zebrafish Fly
neuron projection guidance GO:0097485 24 0.329
regulation of signal transduction GO:0009966 318 0.327
Human
cellular component morphogenesis GO:0032989 155 0.327
cell adhesion GO:0007155 110 0.324
Human Fly
rna biosynthetic process GO:0032774 380 0.321
head development GO:0060322 247 0.320
Human Mouse Fly
enzyme linked receptor protein signaling pathway GO:0007167 116 0.316
signal transduction by phosphorylation GO:0023014 144 0.308
positive regulation of cell communication GO:0010647 271 0.301
taxis GO:0042330 67 0.293
cell projection morphogenesis GO:0048858 123 0.287
epithelium development GO:0060429 96 0.286
Human Zebrafish Mouse Fly
regulation of phosphate metabolic process GO:0019220 349 0.284
axonogenesis GO:0007409 71 0.282
regulation of molecular function GO:0065009 398 0.276
Human
regulation of rna metabolic process GO:0051252 391 0.276
positive regulation of developmental process GO:0051094 283 0.269
Human
neuron projection morphogenesis GO:0048812 122 0.266
locomotion GO:0040011 237 0.257
cell growth GO:0016049 104 0.253
regulation of protein modification process GO:0031399 194 0.242
positive regulation of response to stimulus GO:0048584 285 0.238
tissue morphogenesis GO:0048729 22 0.235
Zebrafish Mouse
positive regulation of catalytic activity GO:0043085 184 0.231
Human
organ formation GO:0048645 3 0.230
Zebrafish Fly
regulation of programmed cell death GO:0043067 341 0.228
Human
forebrain development GO:0030900 98 0.224
Human Mouse
axon development GO:0061564 96 0.224
biological adhesion GO:0022610 110 0.223
Human Fly
regulation of nervous system development GO:0051960 264 0.222
regulation of intracellular signal transduction GO:1902531 218 0.214
positive regulation of hormone secretion GO:0046887 65 0.213
nucleic acid templated transcription GO:0097659 379 0.211
behavior GO:0007610 205 0.211
Human Fly
regulation of phosphorus metabolic process GO:0051174 349 0.210
heart development GO:0007507 72 0.209
Zebrafish Fly
positive regulation of signaling GO:0023056 270 0.206
regulation of cell growth GO:0001558 85 0.206
gliogenesis GO:0042063 93 0.201
positive regulation of multicellular organismal process GO:0051240 387 0.194
Human
neuron death GO:0070997 127 0.188
protein phosphorylation GO:0006468 345 0.182
dorsal ventral axon guidance GO:0033563 1 0.182
regulation of neuron apoptotic process GO:0043523 83 0.180
regulation of mapk cascade GO:0043408 116 0.179
cell cell signaling GO:0007267 335 0.178
regulation of catalytic activity GO:0050790 304 0.175
Human
apoptotic process GO:0006915 381 0.174
Human
regeneration GO:0031099 163 0.171
negative regulation of macromolecule metabolic process GO:0010605 260 0.170
positive regulation of phosphorylation GO:0042327 177 0.167
positive regulation of molecular function GO:0044093 230 0.164
Human
g protein coupled receptor signaling pathway GO:0007186 242 0.163
defecation GO:0030421 1 0.162
negative regulation of metabolic process GO:0009892 331 0.161
organ morphogenesis GO:0009887 75 0.160
Zebrafish Mouse Fly
intracellular signal transduction GO:0035556 314 0.159
transcription dna templated GO:0006351 377 0.156
reproduction GO:0000003 245 0.154
localization of cell GO:0051674 202 0.153
Human Zebrafish Fly
negative regulation of neuron differentiation GO:0045665 62 0.146
response to inorganic substance GO:0010035 377 0.144
negative regulation of cell development GO:0010721 82 0.142
gland development GO:0048732 155 0.141
Human Mouse Fly
development of primary sexual characteristics GO:0045137 107 0.141
Fly
positive regulation of cell proliferation GO:0008284 249 0.141
cell morphogenesis involved in differentiation GO:0000904 119 0.141
positive regulation of phosphorus metabolic process GO:0010562 262 0.140
positive regulation of peptide hormone secretion GO:0090277 50 0.139
cytoskeleton organization GO:0007010 111 0.139
cellular component assembly GO:0022607 360 0.136
regulation of neuron death GO:1901214 115 0.135
developmental growth involved in morphogenesis GO:0060560 33 0.131
Mouse
response to wounding GO:0009611 254 0.130
negative regulation of programmed cell death GO:0043069 183 0.129
cellular amino acid metabolic process GO:0006520 107 0.125
regulation of neuron projection development GO:0010975 161 0.124
cellular amine metabolic process GO:0044106 38 0.124
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.124
single organism reproductive process GO:0044702 297 0.123
Fly
regulation of neurogenesis GO:0050767 247 0.120
single organismal cell cell adhesion GO:0016337 42 0.117
Fly
regulation of neuron differentiation GO:0045664 208 0.116
neuron development GO:0048666 286 0.115
comma shaped body morphogenesis GO:0072049 2 0.115
regulation of locomotion GO:0040012 148 0.114
Human Fly
circulatory system development GO:0072359 134 0.112
Human Zebrafish Fly
developmental process involved in reproduction GO:0003006 159 0.111
Fly
muscle cell proliferation GO:0033002 84 0.111
regulation of synaptic vesicle recycling GO:1903421 1 0.110
regulation of cellular amino acid metabolic process GO:0006521 2 0.108
negative regulation of cellular metabolic process GO:0031324 281 0.107
brain development GO:0007420 247 0.107
Human Mouse Fly
regulation of extent of cell growth GO:0061387 25 0.107
regulation of cell projection organization GO:0031344 175 0.106
negative regulation of cell death GO:0060548 229 0.106
regulation of cell development GO:0060284 263 0.104
response to corticosteroid GO:0031960 235 0.104
regulation of growth GO:0040008 105 0.104
metanephric glomerulus development GO:0072224 3 0.103
reproductive system development GO:0061458 128 0.103
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.101
positive regulation of nervous system development GO:0051962 178 0.101
Human
cell projection organization GO:0030030 302 0.100
response to peptide hormone GO:0043434 278 0.100
cellular component biogenesis GO:0044085 368 0.099
response to glucocorticoid GO:0051384 223 0.098
divalent inorganic cation homeostasis GO:0072507 165 0.098
protein complex subunit organization GO:0071822 302 0.097
negative regulation of cellular biosynthetic process GO:0031327 161 0.096
positive regulation of cell differentiation GO:0045597 217 0.095
Human
positive regulation of signal transduction GO:0009967 175 0.095
telencephalon development GO:0021537 62 0.094
Human Mouse
multicellular organismal reproductive process GO:0048609 233 0.094
actin cytoskeleton organization GO:0030036 73 0.093
central nervous system neuron development GO:0021954 5 0.093
Human Mouse
defense response GO:0006952 194 0.092
response to ketone GO:1901654 182 0.091
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.090
regulation of kinase activity GO:0043549 117 0.089
regulation of phosphorylation GO:0042325 248 0.088
immune response GO:0006955 104 0.088
vesicle mediated transport GO:0016192 181 0.087
regulation of protein metabolic process GO:0051246 289 0.086
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.085
regulation of cell proliferation GO:0042127 359 0.084
Human Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.083
response to ethanol GO:0045471 162 0.083
regulation of anatomical structure morphogenesis GO:0022603 141 0.083
protein autophosphorylation GO:0046777 66 0.082
cardiovascular system development GO:0072358 134 0.082
Human Zebrafish Fly
positive regulation of hydrolase activity GO:0051345 86 0.081
Human
regulation of erk1 and erk2 cascade GO:0070372 41 0.081
negative regulation of gene expression GO:0010629 199 0.081
dendrite development GO:0016358 72 0.080
positive regulation of gene expression GO:0010628 244 0.079
aging GO:0007568 241 0.079
dendrite morphogenesis GO:0048813 43 0.077
regulation of apoptotic process GO:0042981 335 0.077
Human
chemotaxis GO:0006935 66 0.075
positive regulation of cellular component organization GO:0051130 200 0.074
Human
cellular response to glucocorticoid stimulus GO:0071385 68 0.073
negative regulation of cell differentiation GO:0045596 99 0.073
actin filament based process GO:0030029 86 0.073
regulation of cell motility GO:2000145 131 0.072
Fly
organic hydroxy compound metabolic process GO:1901615 115 0.072
neurological system process GO:0050877 219 0.070
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.069
negative regulation of biosynthetic process GO:0009890 168 0.068
multicellular organism reproduction GO:0032504 233 0.067
erk1 and erk2 cascade GO:0070371 48 0.067
salivary gland development GO:0007431 3 0.067
Fly
motor neuron axon guidance GO:0008045 1 0.067
Fly
positive regulation of transcription dna templated GO:0045893 197 0.066
positive regulation of intracellular signal transduction GO:1902533 138 0.065
positive regulation of rna metabolic process GO:0051254 203 0.065
protein complex biogenesis GO:0070271 263 0.065
cellular response to endogenous stimulus GO:0071495 377 0.064
positive regulation of protein kinase activity GO:0045860 73 0.063
mapk cascade GO:0000165 140 0.062
carbohydrate derivative metabolic process GO:1901135 346 0.062
metanephric comma shaped body morphogenesis GO:0072278 2 0.061
macromolecular complex subunit organization GO:0043933 339 0.061
negative regulation of neuron apoptotic process GO:0043524 45 0.060
regulation of synaptic transmission GO:0050804 141 0.059
regulation of cellular amine metabolic process GO:0033238 8 0.059
neuron projection extension GO:1990138 26 0.059
reproductive process GO:0022414 372 0.058
Fly
organonitrogen compound biosynthetic process GO:1901566 167 0.058
female sex differentiation GO:0046660 59 0.058
striated muscle tissue development GO:0014706 58 0.058
transmission of nerve impulse GO:0019226 42 0.057
positive regulation of cell development GO:0010720 176 0.057
Human
response to oxygen levels GO:0070482 265 0.056
negative regulation of phosphate metabolic process GO:0045936 80 0.055
regulation of peptide hormone secretion GO:0090276 80 0.055
amine metabolic process GO:0009308 38 0.055
negative regulation of phosphorus metabolic process GO:0010563 80 0.055
negative regulation of response to stimulus GO:0048585 155 0.055
Human
regulation of cell adhesion GO:0030155 52 0.054
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.054
axon extension GO:0048675 26 0.053
negative regulation of transcription dna templated GO:0045892 116 0.053
positive regulation of kinase activity GO:0033674 77 0.052
positive regulation of programmed cell death GO:0043068 157 0.052
Human
regulation of smooth muscle cell proliferation GO:0048660 75 0.051
positive regulation of mapk cascade GO:0043410 92 0.051
anatomical structure formation involved in morphogenesis GO:0048646 83 0.050
Human Zebrafish Fly
kidney development GO:0001822 67 0.050
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.050
gonad development GO:0008406 104 0.050
Fly
muscle structure development GO:0061061 87 0.049
positive regulation of transport GO:0051050 245 0.049
response to dexamethasone GO:0071548 49 0.048
muscle tissue development GO:0060537 58 0.048
negative regulation of multicellular organismal process GO:0051241 203 0.048
Human
positive regulation of nucleic acid templated transcription GO:1903508 197 0.047
positive regulation of transferase activity GO:0051347 81 0.047
cellular response to steroid hormone stimulus GO:0071383 93 0.047
exploration behavior GO:0035640 1 0.047
single organism organelle organization GO:1902589 180 0.047
embryonic skeletal system morphogenesis GO:0048704 3 0.047
multi organism reproductive process GO:0044703 262 0.047
cardiac ventricle development GO:0003231 1 0.047
cellular response to corticosteroid stimulus GO:0071384 69 0.046
regulation of membrane potential GO:0042391 110 0.046
response to oxidative stress GO:0006979 186 0.046
response to insulin GO:0032868 133 0.046
regulation of response to stress GO:0080134 126 0.046
action potential GO:0001508 54 0.045
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.045
response to extracellular stimulus GO:0009991 380 0.044
regulation of cellular component movement GO:0051270 150 0.044
Fly
ribonucleotide metabolic process GO:0009259 231 0.044
positive regulation of phosphate metabolic process GO:0045937 262 0.044
regulation of defense response GO:0031347 68 0.043
cardiac conduction GO:0061337 2 0.043
phenol containing compound metabolic process GO:0018958 30 0.043
reproductive structure development GO:0048608 128 0.043
Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.042
regulation of heart rate GO:0002027 16 0.042
neural crest cell development GO:0014032 2 0.042
response to progesterone GO:0032570 48 0.042
ovulation cycle process GO:0022602 50 0.042
regulation of axon extension GO:0030516 24 0.042
regulation of immune system process GO:0002682 123 0.042
sex differentiation GO:0007548 113 0.042
Fly
positive regulation of biosynthetic process GO:0009891 319 0.041
synaptic transmission GO:0007268 235 0.041
monovalent inorganic cation transport GO:0015672 172 0.041
response to ammonium ion GO:0060359 71 0.041
smooth muscle cell proliferation GO:0048659 77 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
peptidyl amino acid modification GO:0018193 126 0.040
negative regulation of rna metabolic process GO:0051253 123 0.040
regulation of behavior GO:0050795 61 0.040
Human
regulation of protein phosphorylation GO:0001932 183 0.040
positive regulation of protein phosphorylation GO:0001934 135 0.039
response to hypoxia GO:0001666 231 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
positive regulation of neuron differentiation GO:0045666 126 0.039
Human
multicellular organismal signaling GO:0035637 44 0.039
development of primary female sexual characteristics GO:0046545 56 0.039
regulation of developmental growth GO:0048638 45 0.039
regulation of cell migration GO:0030334 128 0.039
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.039
cerebral cortex tangential migration GO:0021800 1 0.038
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.038
cellular cation homeostasis GO:0030003 180 0.038
wound healing GO:0042060 122 0.038
response to reactive oxygen species GO:0000302 120 0.037
learning or memory GO:0007611 90 0.037
regulation of cellular component size GO:0032535 51 0.037
metanephric s shaped body morphogenesis GO:0072284 2 0.037
regulation of catabolic process GO:0009894 113 0.037
negative regulation of signal transduction GO:0009968 83 0.037
Human
retinal ganglion cell axon guidance GO:0031290 1 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.037
response to decreased oxygen levels GO:0036293 237 0.036
positive regulation of growth GO:0045927 55 0.036
cardiac chamber development GO:0003205 1 0.036
gastrulation GO:0007369 2 0.036
regulation of hormone secretion GO:0046883 106 0.036
response to radiation GO:0009314 137 0.035
negative regulation of nervous system development GO:0051961 79 0.035
neural crest cell migration GO:0001755 1 0.035
dna metabolic process GO:0006259 96 0.035
muscle organ development GO:0007517 50 0.034
immune system process GO:0002376 204 0.034
inflammatory response GO:0006954 150 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
response to estradiol GO:0032355 164 0.033
response to peptide GO:1901652 292 0.033
metal ion transport GO:0030001 289 0.033
cellular response to nitrogen compound GO:1901699 210 0.032
cytokine mediated signaling pathway GO:0019221 43 0.032
Human
negative regulation of growth GO:0045926 37 0.032
morphogenesis of an epithelium GO:0002009 20 0.032
Zebrafish Mouse
ion transmembrane transport GO:0034220 365 0.032
response to other organism GO:0051707 220 0.032
negative regulation of neuron death GO:1901215 69 0.031
cellular response to stress GO:0033554 269 0.031
transmembrane transport GO:0055085 412 0.031
positive regulation of nucleotide metabolic process GO:0045981 91 0.031
negative regulation of luteinizing hormone secretion GO:0033685 4 0.031
synapse assembly GO:0007416 29 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.031
ion homeostasis GO:0050801 212 0.031
positive regulation of neuron death GO:1901216 43 0.030
peptide secretion GO:0002790 86 0.030
positive regulation of neuron projection development GO:0010976 99 0.030
Human
cellular response to cytokine stimulus GO:0071345 127 0.030
Human
organelle organization GO:0006996 266 0.030
macromolecular complex assembly GO:0065003 273 0.030
epithelial cell differentiation GO:0030855 71 0.030
ovulation cycle GO:0042698 67 0.030
purine containing compound metabolic process GO:0072521 253 0.029
regulation of organ formation GO:0003156 2 0.029
regulation of axonogenesis GO:0050770 37 0.029
Human
organophosphate metabolic process GO:0019637 370 0.029
cell activation GO:0001775 97 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
negative regulation of axon guidance GO:1902668 3 0.029
negative regulation of cell communication GO:0010648 158 0.029
Human
organic cyclic compound catabolic process GO:1901361 175 0.029
carboxylic acid metabolic process GO:0019752 289 0.028
regulation of purine nucleotide metabolic process GO:1900542 115 0.028
regulation of cell size GO:0008361 37 0.028
negative regulation of cell proliferation GO:0008285 119 0.028
Human Mouse
hematopoietic or lymphoid organ development GO:0048534 36 0.028
sexual reproduction GO:0019953 148 0.028
regulation of leukocyte differentiation GO:1902105 20 0.028
organonitrogen compound catabolic process GO:1901565 179 0.028
regulation of organelle organization GO:0033043 80 0.027
nucleotide metabolic process GO:0009117 279 0.027
sodium ion transmembrane transport GO:0035725 67 0.027
locomotory exploration behavior GO:0035641 1 0.027
regulation of cellular catabolic process GO:0031329 101 0.027
leukocyte activation GO:0045321 76 0.027
synapse organization GO:0050808 46 0.027
glial cell differentiation GO:0010001 65 0.026
axon ensheathment GO:0008366 40 0.026
cell cycle process GO:0022402 57 0.026
regulation of cellular component biogenesis GO:0044087 86 0.026
regulation of transferase activity GO:0051338 123 0.026
single organism cell adhesion GO:0098602 46 0.026
Fly
regulation of small gtpase mediated signal transduction GO:0051056 48 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
regulation of anatomical structure size GO:0090066 135 0.026
positive regulation of immune response GO:0050778 42 0.026
response to estrogen GO:0043627 232 0.026
positive regulation of immune system process GO:0002684 90 0.025
protein complex assembly GO:0006461 263 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
positive regulation of neuron apoptotic process GO:0043525 33 0.025
neuron fate commitment GO:0048663 4 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.025
response to electrical stimulus GO:0051602 56 0.025
cell communication involved in cardiac conduction GO:0086065 2 0.025
b cell differentiation GO:0030183 2 0.025
negative regulation of neurogenesis GO:0050768 78 0.025
protein heterooligomerization GO:0051291 89 0.025
regulation of peptide transport GO:0090087 87 0.025
positive regulation of nucleotide catabolic process GO:0030813 53 0.024
regulation of system process GO:0044057 208 0.024
glial cell migration GO:0008347 11 0.024
urogenital system development GO:0001655 78 0.024
positive regulation of neurogenesis GO:0050769 165 0.024
Human
ensheathment of neurons GO:0007272 40 0.024
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.023
anterior posterior pattern specification GO:0009952 1 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
heterocycle catabolic process GO:0046700 167 0.023
positive regulation of protein metabolic process GO:0051247 178 0.023
Human
small gtpase mediated signal transduction GO:0007264 36 0.023
single organism behavior GO:0044708 130 0.023
epithelial cell migration GO:0010631 19 0.023
Human Fly
regulation of synaptic transmission glutamatergic GO:0051966 26 0.023
skeletal muscle tissue development GO:0007519 31 0.022
eye development GO:0001654 50 0.022
hormone transport GO:0009914 121 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
rhythmic process GO:0048511 156 0.022
Fly
regulation of actin cytoskeleton organization GO:0032956 30 0.022
regulation of nucleoside metabolic process GO:0009118 66 0.022
positive regulation of heart contraction GO:0045823 15 0.022
neuronal action potential GO:0019228 35 0.022
diencephalon development GO:0021536 21 0.021
positive regulation of blood circulation GO:1903524 65 0.021
jak stat cascade GO:0007259 26 0.021
calcium ion homeostasis GO:0055074 162 0.021
secretion by cell GO:0032940 248 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
positive regulation of peptide secretion GO:0002793 52 0.021
cell substrate adhesion GO:0031589 29 0.020
actin filament bundle organization GO:0061572 19 0.020
stress activated protein kinase signaling cascade GO:0031098 37 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.020
peptidyl tyrosine phosphorylation GO:0018108 72 0.020
organic hydroxy compound biosynthetic process GO:1901617 51 0.020
regulation of response to wounding GO:1903034 69 0.020
forebrain neuron development GO:0021884 3 0.020
Human Mouse
spinal cord development GO:0021510 27 0.020
cellular protein localization GO:0034613 122 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
positive regulation of cellular catabolic process GO:0031331 71 0.019
purine nucleoside triphosphate catabolic process GO:0009146 122 0.019
regulation of defecation GO:2000292 1 0.019
glomerulus development GO:0032835 10 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.019
axon extension involved in axon guidance GO:0048846 6 0.019
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.019
gamete generation GO:0007276 124 0.019
cellular ketone metabolic process GO:0042180 51 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
glomerulus morphogenesis GO:0072102 1 0.019
central nervous system neuron axonogenesis GO:0021955 1 0.019
organ growth GO:0035265 24 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
cerebellar purkinje cell layer development GO:0021680 2 0.019
myelination GO:0042552 39 0.019
specification of organ identity GO:0010092 2 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
negative regulation of cell growth GO:0030308 33 0.018
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
Human
cation transport GO:0006812 382 0.018
response to cytokine GO:0034097 215 0.018
Human
central nervous system neuron differentiation GO:0021953 17 0.018
Human Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.018
peptidyl tyrosine modification GO:0018212 72 0.018
regulation of protein serine threonine kinase activity GO:0071900 64 0.018
negative regulation of immune system process GO:0002683 39 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
Human
regulation of inflammatory response GO:0050727 48 0.018
gtp catabolic process GO:0006184 71 0.018
response to alkaloid GO:0043279 132 0.018
positive regulation of leukocyte activation GO:0002696 30 0.018
heart contraction GO:0060047 57 0.017
cellular response to fibroblast growth factor stimulus GO:0044344 24 0.017
regulation of gtpase activity GO:0043087 57 0.017
organic acid metabolic process GO:0006082 292 0.017
protein oligomerization GO:0051259 191 0.017
embryonic cranial skeleton morphogenesis GO:0048701 2 0.017
regulation of gtp catabolic process GO:0033124 58 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
Human
ras protein signal transduction GO:0007265 29 0.017
intracellular receptor signaling pathway GO:0030522 35 0.017
positive regulation of catabolic process GO:0009896 78 0.017
peptide transport GO:0015833 97 0.017
response to nutrient GO:0007584 248 0.017
negative regulation of calcium ion import GO:0090281 2 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
positive regulation of locomotion GO:0040017 102 0.017
neural crest cell differentiation GO:0014033 2 0.017
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 1 0.017
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 24 0.017
cellular response to peptide hormone stimulus GO:0071375 120 0.017
mesoderm development GO:0007498 2 0.017
gastric inhibitory peptide signaling pathway GO:0038192 1 0.017
regulation of map kinase activity GO:0043405 53 0.017
cell cell signaling involved in cell fate commitment GO:0045168 2 0.017
purine nucleotide metabolic process GO:0006163 229 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
regulation of metanephros development GO:0072215 4 0.016
sensory perception of pain GO:0019233 73 0.016
positive regulation of developmental growth GO:0048639 29 0.016
response to biotic stimulus GO:0009607 226 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
kidney morphogenesis GO:0060993 13 0.016
tissue regeneration GO:0042246 36 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
regulation of protein transport GO:0051223 68 0.016
nitrogen compound transport GO:0071705 229 0.016
coronary vasculature morphogenesis GO:0060977 3 0.016

Robo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.039
disease of cellular proliferation DOID:14566 0 0.039
gastrointestinal system cancer DOID:3119 0 0.026
organ system cancer DOID:0050686 0 0.026
colon carcinoma DOID:1520 0 0.017
large intestine cancer DOID:5672 0 0.017
colon cancer DOID:219 0 0.017
intestinal cancer DOID:10155 0 0.017
colorectal cancer DOID:9256 0 0.017