Rattus norvegicus

47 known processes

Rpe65

retinal pigment epithelium 65

Rpe65 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of molecular function GO:0065009 398 0.243
regulation of phosphate metabolic process GO:0019220 349 0.217
transmembrane transport GO:0055085 412 0.213
response to carbohydrate GO:0009743 183 0.192
single organism biosynthetic process GO:0044711 342 0.170
regulation of signal transduction GO:0009966 318 0.142
ion transmembrane transport GO:0034220 365 0.140
regulation of phosphorus metabolic process GO:0051174 349 0.127
positive regulation of phosphorus metabolic process GO:0010562 262 0.118
response to estrogen GO:0043627 232 0.118
macromolecular complex subunit organization GO:0043933 339 0.113
intracellular signal transduction GO:0035556 314 0.106
reproductive process GO:0022414 372 0.106
anion transport GO:0006820 178 0.104
organophosphate metabolic process GO:0019637 370 0.103
cellular response to endogenous stimulus GO:0071495 377 0.102
response to inorganic substance GO:0010035 377 0.098
cation transport GO:0006812 382 0.095
reproduction GO:0000003 245 0.092
neuron differentiation GO:0030182 368 0.089
positive regulation of phosphate metabolic process GO:0045937 262 0.084
regulation of phosphorylation GO:0042325 248 0.084
regulation of programmed cell death GO:0043067 341 0.082
protein phosphorylation GO:0006468 345 0.082
cation transmembrane transport GO:0098655 263 0.082
response to nutrient levels GO:0031667 370 0.079
cellular response to organonitrogen compound GO:0071417 197 0.078
nucleotide metabolic process GO:0009117 279 0.078
positive regulation of response to stimulus GO:0048584 285 0.071
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.069
multicellular organism reproduction GO:0032504 233 0.068
homeostatic process GO:0042592 331 0.068
response to alkaloid GO:0043279 132 0.067
protein complex subunit organization GO:0071822 302 0.066
response to hexose GO:0009746 144 0.065
circadian rhythm GO:0007623 88 0.064
inflammatory response GO:0006954 150 0.063
cellular response to organic cyclic compound GO:0071407 202 0.062
brain development GO:0007420 247 0.061
aging GO:0007568 241 0.060
purine ribonucleotide metabolic process GO:0009150 227 0.057
oxoacid metabolic process GO:0043436 290 0.057
negative regulation of metabolic process GO:0009892 331 0.055
transcription dna templated GO:0006351 377 0.055
inorganic ion transmembrane transport GO:0098660 229 0.054
cellular component movement GO:0006928 248 0.054
cellular chemical homeostasis GO:0055082 247 0.054
response to other organism GO:0051707 220 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.054
regulation of apoptotic process GO:0042981 335 0.053
protein complex assembly GO:0006461 263 0.053
positive regulation of signal transduction GO:0009967 175 0.053
organic substance catabolic process GO:1901575 316 0.053
positive regulation of gene expression GO:0010628 244 0.051
carboxylic acid transport GO:0046942 115 0.051
neuron projection development GO:0031175 273 0.051
response to biotic stimulus GO:0009607 226 0.051
protein oligomerization GO:0051259 191 0.050
organic anion transport GO:0015711 132 0.049
carboxylic acid metabolic process GO:0019752 289 0.049
positive regulation of molecular function GO:0044093 230 0.049
regulation of ion transport GO:0043269 245 0.049
g protein coupled receptor signaling pathway GO:0007186 242 0.048
regulation of protein modification process GO:0031399 194 0.048
regulation of protein metabolic process GO:0051246 289 0.047
response to light stimulus GO:0009416 52 0.047
regulation of metal ion transport GO:0010959 118 0.047
nucleobase containing small molecule metabolic process GO:0055086 316 0.047
regulation of catalytic activity GO:0050790 304 0.046
regulation of protein phosphorylation GO:0001932 183 0.046
anatomical structure morphogenesis GO:0009653 298 0.045
positive regulation of rna metabolic process GO:0051254 203 0.045
regulation of neuron differentiation GO:0045664 208 0.045
organic acid metabolic process GO:0006082 292 0.044
protein homooligomerization GO:0051260 91 0.044
regulation of nucleic acid templated transcription GO:1903506 380 0.044
protein complex biogenesis GO:0070271 263 0.044
regulation of growth GO:0040008 105 0.044
alcohol metabolic process GO:0006066 77 0.044
negative regulation of apoptotic process GO:0043066 181 0.043
inorganic cation transmembrane transport GO:0098662 202 0.043
regulation of cellular localization GO:0060341 263 0.043
regulation of cellular protein metabolic process GO:0032268 267 0.043
programmed cell death GO:0012501 392 0.042
response to cytokine GO:0034097 215 0.042
negative regulation of cell death GO:0060548 229 0.042
organic hydroxy compound metabolic process GO:1901615 115 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.042
response to bacterium GO:0009617 200 0.042
rhythmic process GO:0048511 156 0.041
response to lipopolysaccharide GO:0032496 191 0.041
nitrogen compound transport GO:0071705 229 0.041
regulation of cell proliferation GO:0042127 359 0.041
regulation of kinase activity GO:0043549 117 0.041
positive regulation of phosphorylation GO:0042327 177 0.040
cellular component biogenesis GO:0044085 368 0.040
regulation of cell development GO:0060284 263 0.038
lipid biosynthetic process GO:0008610 128 0.038
positive regulation of protein metabolic process GO:0051247 178 0.038
positive regulation of neurogenesis GO:0050769 165 0.038
organelle organization GO:0006996 266 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
metal ion transport GO:0030001 289 0.037
growth GO:0040007 165 0.037
macromolecular complex assembly GO:0065003 273 0.037
multicellular organismal reproductive process GO:0048609 233 0.037
rna biosynthetic process GO:0032774 380 0.036
positive regulation of protein phosphorylation GO:0001934 135 0.036
response to glucocorticoid GO:0051384 223 0.036
regulation of neurogenesis GO:0050767 247 0.036
regulation of hormone levels GO:0010817 187 0.036
synaptic transmission GO:0007268 235 0.036
cellular homeostasis GO:0019725 252 0.036
amine metabolic process GO:0009308 38 0.036
cellular response to alkaloid GO:0071312 25 0.036
regulation of neuron projection development GO:0010975 161 0.035
purine nucleotide metabolic process GO:0006163 229 0.035
nucleic acid templated transcription GO:0097659 379 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
cellular catabolic process GO:0044248 295 0.034
anion transmembrane transport GO:0098656 77 0.034
positive regulation of biosynthetic process GO:0009891 319 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.034
negative regulation of biosynthetic process GO:0009890 168 0.034
response to estradiol GO:0032355 164 0.033
response to molecule of bacterial origin GO:0002237 194 0.033
positive regulation of catalytic activity GO:0043085 184 0.033
positive regulation of intracellular signal transduction GO:1902533 138 0.033
response to extracellular stimulus GO:0009991 380 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
positive regulation of rna biosynthetic process GO:1902680 197 0.032
lipid metabolic process GO:0006629 283 0.032
cell cell signaling GO:0007267 335 0.032
single organism reproductive process GO:0044702 297 0.032
positive regulation of signaling GO:0023056 270 0.032
signal transduction by phosphorylation GO:0023014 144 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
regulation of cellular component organization GO:0051128 368 0.031
response to monosaccharide GO:0034284 159 0.031
neuron development GO:0048666 286 0.031
apoptotic process GO:0006915 381 0.031
positive regulation of cell communication GO:0010647 271 0.030
rna metabolic process GO:0016070 406 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
regulation of membrane potential GO:0042391 110 0.030
neuron projection morphogenesis GO:0048812 122 0.030
response to radiation GO:0009314 137 0.030
cellular amino acid metabolic process GO:0006520 107 0.029
heterocycle catabolic process GO:0046700 167 0.029
cellular lipid metabolic process GO:0044255 208 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
glutamate receptor signaling pathway GO:0007215 43 0.029
regulation of transcription dna templated GO:0006355 374 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
protein localization GO:0008104 191 0.029
ribose phosphate metabolic process GO:0019693 235 0.028
organophosphate biosynthetic process GO:0090407 143 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.028
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.028
response to acid chemical GO:0001101 222 0.027
regulation of system process GO:0044057 208 0.027
regulation of mapk cascade GO:0043408 116 0.027
regulation of rna metabolic process GO:0051252 391 0.027
cellular ketone metabolic process GO:0042180 51 0.026
mapk cascade GO:0000165 140 0.026
peptidyl tyrosine phosphorylation GO:0018108 72 0.026
peptidyl amino acid modification GO:0018193 126 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
organophosphate catabolic process GO:0046434 148 0.026
response to purine containing compound GO:0014074 126 0.026
regulation of anatomical structure size GO:0090066 135 0.025
cell projection organization GO:0030030 302 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
cellular component assembly GO:0022607 360 0.025
response to peptide GO:1901652 292 0.025
central nervous system development GO:0007417 311 0.025
cellular response to abiotic stimulus GO:0071214 85 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
ribonucleoside triphosphate catabolic process GO:0009203 122 0.025
steroid metabolic process GO:0008202 73 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
cellular amine metabolic process GO:0044106 38 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
response to glucose GO:0009749 136 0.024
neurological system process GO:0050877 219 0.024
regulation of transferase activity GO:0051338 123 0.024
chemical homeostasis GO:0048878 292 0.024
macromolecule localization GO:0033036 252 0.024
neural precursor cell proliferation GO:0061351 23 0.023
l glutamate import GO:0051938 2 0.023
purine nucleotide catabolic process GO:0006195 136 0.023
nucleoside metabolic process GO:0009116 179 0.023
tissue development GO:0009888 252 0.023
single organism behavior GO:0044708 130 0.023
cellular response to stress GO:0033554 269 0.023
activation of protein kinase activity GO:0032147 47 0.023
purine containing compound metabolic process GO:0072521 253 0.023
catabolic process GO:0009056 351 0.023
positive regulation of nervous system development GO:0051962 178 0.022
sex differentiation GO:0007548 113 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
regulation of transmembrane transport GO:0034762 122 0.022
developmental process involved in reproduction GO:0003006 159 0.022
response to blue light GO:0009637 1 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
vasoconstriction GO:0042310 54 0.022
cyclic purine nucleotide metabolic process GO:0052652 62 0.022
negative regulation of gene expression GO:0010629 199 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
regulation of response to external stimulus GO:0032101 106 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
response to corticosteroid GO:0031960 235 0.021
positive regulation of protein modification process GO:0031401 142 0.021
positive regulation of transport GO:0051050 245 0.021
response to growth factor GO:0070848 189 0.021
intracellular transport GO:0046907 185 0.021
carbohydrate homeostasis GO:0033500 75 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
regulation of epithelial cell proliferation GO:0050678 49 0.020
muscle system process GO:0003012 115 0.020
cellular response to hexose stimulus GO:0071331 65 0.020
cell morphogenesis GO:0000902 142 0.020
camp biosynthetic process GO:0006171 47 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
secretion GO:0046903 307 0.020
positive regulation of response to wounding GO:1903036 34 0.020
response to ketone GO:1901654 182 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
epithelium development GO:0060429 96 0.020
single organism catabolic process GO:0044712 283 0.020
b cell differentiation GO:0030183 2 0.019
negative regulation of signaling GO:0023057 157 0.019
response to organophosphorus GO:0046683 102 0.019
cellular ion homeostasis GO:0006873 184 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.019
positive regulation of mapk cascade GO:0043410 92 0.019
cell part morphogenesis GO:0032990 123 0.019
positive regulation of kinase activity GO:0033674 77 0.019
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.019
regulation of hormone secretion GO:0046883 106 0.019
response to ethanol GO:0045471 162 0.019
regulation of cell differentiation GO:0045595 320 0.019
head development GO:0060322 247 0.019
cellular protein localization GO:0034613 122 0.019
reproductive structure development GO:0048608 128 0.019
glucose homeostasis GO:0042593 75 0.019
secretion by cell GO:0032940 248 0.019
negative regulation of transcription dna templated GO:0045892 116 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
cellular response to histamine GO:0071420 3 0.018
multicellular organism growth GO:0035264 1 0.018
regulation of response to stress GO:0080134 126 0.018
response to ammonium ion GO:0060359 71 0.018
negative regulation of transport GO:0051051 136 0.018
phototransduction visible light GO:0007603 2 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
response to external biotic stimulus GO:0043207 221 0.018
heart morphogenesis GO:0003007 3 0.018
divalent metal ion transport GO:0070838 132 0.018
glandular epithelial cell differentiation GO:0002067 4 0.018
monocarboxylic acid metabolic process GO:0032787 152 0.018
positive regulation of protein kinase activity GO:0045860 73 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
negative regulation of molecular function GO:0044092 133 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
cell migration GO:0016477 197 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
sexual reproduction GO:0019953 148 0.017
response to peptide hormone GO:0043434 278 0.017
response to mineralocorticoid GO:0051385 49 0.017
response to camp GO:0051591 91 0.017
neuron neuron synaptic transmission GO:0007270 60 0.017
cellular component morphogenesis GO:0032989 155 0.017
regulation of protein kinase activity GO:0045859 105 0.017
small molecule biosynthetic process GO:0044283 124 0.017
endocrine system development GO:0035270 30 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
axis specification GO:0009798 4 0.017
peptidyl tyrosine modification GO:0018212 72 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
cellular response to glucose stimulus GO:0071333 65 0.017
regulation of secretion by cell GO:1903530 208 0.017
positive regulation of cell death GO:0010942 184 0.017
synaptic transmission gabaergic GO:0051932 22 0.017
regulation of multicellular organismal development GO:2000026 376 0.016
hormone metabolic process GO:0042445 69 0.016
gland development GO:0048732 155 0.016
blood circulation GO:0008015 183 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
gliogenesis GO:0042063 93 0.016
leukocyte activation GO:0045321 76 0.016
positive regulation of transferase activity GO:0051347 81 0.016
cellular response to carbohydrate stimulus GO:0071322 72 0.016
purine containing compound catabolic process GO:0072523 138 0.016
hormone transport GO:0009914 121 0.016
gastrulation GO:0007369 2 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
wound healing GO:0042060 122 0.016
ribonucleotide biosynthetic process GO:0009260 85 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
positive regulation of secretion GO:0051047 140 0.015
response to mechanical stimulus GO:0009612 134 0.015
neuron death GO:0070997 127 0.015
glycerolipid metabolic process GO:0046486 67 0.015
reproductive system development GO:0061458 128 0.015
organic acid transport GO:0015849 116 0.015
potassium ion transport GO:0006813 97 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
response to morphine GO:0043278 27 0.015
regulation of secretion GO:0051046 224 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
cell growth GO:0016049 104 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
eye morphogenesis GO:0048592 4 0.014
single organism organelle organization GO:1902589 180 0.014
terpenoid metabolic process GO:0006721 37 0.014
response to hypoxia GO:0001666 231 0.014
defense response GO:0006952 194 0.014
signal release GO:0023061 145 0.014
muscle contraction GO:0006936 88 0.014
camp metabolic process GO:0046058 63 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
regulation of locomotion GO:0040012 148 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
cell cycle GO:0007049 101 0.014
cerebellar granule cell precursor proliferation GO:0021930 1 0.014
positive regulation of developmental process GO:0051094 283 0.014
regulation of synaptic transmission GO:0050804 141 0.014
multi organism reproductive process GO:0044703 262 0.014
response to wounding GO:0009611 254 0.014
regulation of blood vessel size GO:0050880 89 0.014
actin filament based process GO:0030029 86 0.014
phospholipid metabolic process GO:0006644 61 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
action potential GO:0001508 54 0.013
response to hydrogen peroxide GO:0042542 89 0.013
activation of mapkk activity GO:0000186 18 0.013
positive regulation of fat cell proliferation GO:0070346 1 0.013
cellular response to lipid GO:0071396 201 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.013
cell projection morphogenesis GO:0048858 123 0.013
amide transport GO:0042886 105 0.013
aromatic compound catabolic process GO:0019439 168 0.013
regulation of cell projection organization GO:0031344 175 0.013
developmental growth GO:0048589 100 0.013
response to insulin GO:0032868 133 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
sensory perception of pain GO:0019233 73 0.012
ras protein signal transduction GO:0007265 29 0.012
response to metal ion GO:0010038 253 0.012
regulation of behavior GO:0050795 61 0.012
nerve development GO:0021675 11 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
response to fluoride GO:1902617 3 0.012
developmental growth involved in morphogenesis GO:0060560 33 0.012
cardiac muscle cell contraction GO:0086003 10 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
ion homeostasis GO:0050801 212 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
regulation of transporter activity GO:0032409 50 0.012
proteolysis GO:0006508 175 0.012
spermatogenesis GO:0007283 99 0.012
regulation of neuron death GO:1901214 115 0.012
cellular glucose homeostasis GO:0001678 66 0.012
cellular response to acid chemical GO:0071229 75 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
regulation of nucleotide biosynthetic process GO:0030808 47 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
regulation of cellular component movement GO:0051270 150 0.012
negative regulation of innate immune response GO:0045824 4 0.011
positive regulation of growth GO:0045927 55 0.011
adenohypophysis development GO:0021984 2 0.011
cell type specific apoptotic process GO:0097285 134 0.011
meiotic cell cycle process GO:1903046 3 0.011
cellular response to glucocorticoid stimulus GO:0071385 68 0.011
gonad development GO:0008406 104 0.011
cellular response to corticosteroid stimulus GO:0071384 69 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
inositol trisphosphate biosynthetic process GO:0032959 3 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
male gamete generation GO:0048232 99 0.011
response to toxic substance GO:0009636 133 0.011
response to nicotine GO:0035094 51 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
response to reactive oxygen species GO:0000302 120 0.011
regulation of muscle system process GO:0090257 79 0.011
hormone biosynthetic process GO:0042446 25 0.011
circulatory system development GO:0072359 134 0.011
ossification GO:0001503 70 0.011
regulation of tube size GO:0035150 89 0.011
regulation of ion transmembrane transporter activity GO:0032412 48 0.011
metal ion homeostasis GO:0055065 186 0.011
cation homeostasis GO:0055080 195 0.011
protein transport GO:0015031 132 0.011
regulation of response to wounding GO:1903034 69 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
response to histamine GO:0034776 3 0.011
cellular response to monosaccharide stimulus GO:0071326 67 0.011
hormone secretion GO:0046879 115 0.011
regulation of cell motility GO:2000145 131 0.011
cell proliferation in external granule layer GO:0021924 1 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
cell motility GO:0048870 202 0.010
respiratory system development GO:0060541 45 0.010
positive regulation of cell development GO:0010720 176 0.010
epithelial cell differentiation GO:0030855 71 0.010
response to disaccharide GO:0034285 10 0.010
endochondral bone growth GO:0003416 3 0.010
carbohydrate metabolic process GO:0005975 130 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.010
positive regulation of ion transport GO:0043270 94 0.010
circadian behavior GO:0048512 24 0.010
vesicle organization GO:0016050 29 0.010

Rpe65 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
nervous system disease DOID:863 0 0.055
sensory system disease DOID:0050155 0 0.030
disease of metabolism DOID:0014667 0 0.015
eye and adnexa disease DOID:1492 0 0.014
central nervous system disease DOID:331 0 0.013