Rattus norvegicus

0 known processes

Rt1.aa

MHC class I RT1.Aa alpha-chain

(Aliases: MGC188489)

Rt1.aa biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
antigen processing and presentation of endogenous antigen GO:0019883 1 0.360
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.131
cation transport GO:0006812 382 0.129
regulation of cell killing GO:0031341 12 0.121
choline transport GO:0015871 4 0.112
regulation of immune system process GO:0002682 123 0.111
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.110
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.100
carboxylic acid metabolic process GO:0019752 289 0.091
response to retinoic acid GO:0032526 63 0.088
response to nutrient levels GO:0031667 370 0.088
cellular chemical homeostasis GO:0055082 247 0.081
muscle system process GO:0003012 115 0.080
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.068
cell killing GO:0001906 13 0.063
secretion GO:0046903 307 0.063
chemical homeostasis GO:0048878 292 0.061
cellular cation homeostasis GO:0030003 180 0.059
positive regulation of multicellular organismal process GO:0051240 387 0.059
immune system development GO:0002520 41 0.058
negative regulation of multicellular organismal process GO:0051241 203 0.057
regulation of natural killer cell mediated cytotoxicity GO:0042269 6 0.057
regulation of ion transport GO:0043269 245 0.050
response to extracellular stimulus GO:0009991 380 0.049
response to nutrient GO:0007584 248 0.048
leukocyte activation GO:0045321 76 0.047
positive regulation of immune system process GO:0002684 90 0.046
cellular response to stress GO:0033554 269 0.044
neuron differentiation GO:0030182 368 0.042
cellular response to oxygen containing compound GO:1901701 386 0.041
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.039
cellular calcium ion homeostasis GO:0006874 160 0.038
cellular homeostasis GO:0019725 252 0.038
cellular amino acid metabolic process GO:0006520 107 0.038
sodium ion transport GO:0006814 82 0.037
cellular ion homeostasis GO:0006873 184 0.036
negative regulation of innate immune response GO:0045824 4 0.036
negative regulation of cell killing GO:0031342 5 0.035
defense response GO:0006952 194 0.035
response to external biotic stimulus GO:0043207 221 0.035
lymphocyte activation GO:0046649 43 0.034
biological adhesion GO:0022610 110 0.034
cgmp biosynthetic process GO:0006182 15 0.034
blood circulation GO:0008015 183 0.034
immune system process GO:0002376 204 0.034
regulation of nervous system development GO:0051960 264 0.033
negative regulation of immune system process GO:0002683 39 0.033
positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 0.033
neuron development GO:0048666 286 0.033
negative regulation of cell proliferation GO:0008285 119 0.032
positive regulation of programmed cell death GO:0043068 157 0.032
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.030
t cell activation GO:0042110 29 0.030
regulation of phagocytosis engulfment GO:0060099 4 0.030
regulation of cell migration GO:0030334 128 0.030
cation homeostasis GO:0055080 195 0.030
regulation of system process GO:0044057 208 0.030
negative regulation of cell differentiation GO:0045596 99 0.029
immune response GO:0006955 104 0.029
regulation of cellular component organization GO:0051128 368 0.029
regulation of tolerance induction to nonself antigen GO:0002655 1 0.029
positive regulation of response to stimulus GO:0048584 285 0.028
regulation of metal ion transport GO:0010959 118 0.028
oxoacid metabolic process GO:0043436 290 0.027
ion homeostasis GO:0050801 212 0.027
negative regulation of leukocyte mediated immunity GO:0002704 6 0.027
natural killer cell mediated cytotoxicity GO:0042267 6 0.027
regulation of multicellular organismal development GO:2000026 376 0.026
negative regulation of developmental process GO:0051093 125 0.026
localization of cell GO:0051674 202 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.024
neuron projection development GO:0031175 273 0.024
vesicle mediated transport GO:0016192 181 0.023
organic acid metabolic process GO:0006082 292 0.023
leukocyte mediated cytotoxicity GO:0001909 10 0.023
regulation of cell projection organization GO:0031344 175 0.023
fatty acid metabolic process GO:0006631 99 0.023
regulation of response to external stimulus GO:0032101 106 0.022
regulation of vesicle mediated transport GO:0060627 81 0.022
cellular response to iron ion starvation GO:0010106 1 0.022
regulation of cell development GO:0060284 263 0.022
monocarboxylic acid metabolic process GO:0032787 152 0.021
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.021
sodium ion transmembrane transport GO:0035725 67 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
positive regulation of cellular component movement GO:0051272 102 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
metal ion transport GO:0030001 289 0.019
central nervous system development GO:0007417 311 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
organophosphate metabolic process GO:0019637 370 0.019
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 1 0.019
regulation of catalytic activity GO:0050790 304 0.018
glucose metabolic process GO:0006006 52 0.018
anion transmembrane transport GO:0098656 77 0.018
cellular response to ketone GO:1901655 51 0.018
carboxylic acid transport GO:0046942 115 0.018
positive regulation of molecular function GO:0044093 230 0.018
cellular ketone metabolic process GO:0042180 51 0.018
amine metabolic process GO:0009308 38 0.017
regulation of neuron projection development GO:0010975 161 0.017
sterol homeostasis GO:0055092 3 0.017
circulatory system process GO:0003013 183 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
actin filament based movement GO:0030048 16 0.017
inflammatory response GO:0006954 150 0.017
leukocyte mediated immunity GO:0002443 28 0.017
multicellular organismal signaling GO:0035637 44 0.017
nitrogen compound transport GO:0071705 229 0.017
transmembrane transport GO:0055085 412 0.016
cellular component movement GO:0006928 248 0.016
regulation of endocytosis GO:0030100 42 0.016
gland development GO:0048732 155 0.016
response to organophosphorus GO:0046683 102 0.016
regulation of blood circulation GO:1903522 110 0.016
regulation of cell differentiation GO:0045595 320 0.016
modified amino acid transport GO:0072337 12 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
innate immune response GO:0045087 35 0.016
negative regulation of lymphocyte mediated immunity GO:0002707 5 0.016
regulation of neurogenesis GO:0050767 247 0.016
positive regulation of cell development GO:0010720 176 0.015
single organism intracellular transport GO:1902582 166 0.015
response to tumor cell GO:0002347 4 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
regulation of cell motility GO:2000145 131 0.015
mitotic spindle organization GO:0007052 2 0.015
cytoskeleton dependent cytokinesis GO:0061640 2 0.015
vitamin a metabolic process GO:0006776 2 0.015
metal ion homeostasis GO:0055065 186 0.015
response to molecule of fungal origin GO:0002238 3 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.014
monocarboxylic acid biosynthetic process GO:0072330 48 0.014
defense response to gram positive bacterium GO:0050830 2 0.014
leukocyte cell cell adhesion GO:0007159 4 0.014
negative regulation of nervous system development GO:0051961 79 0.014
transmission of nerve impulse GO:0019226 42 0.014
positive regulation of mitochondrial membrane permeability GO:0035794 1 0.014
regulation of cell activation GO:0050865 50 0.014
cellular component assembly GO:0022607 360 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
cellular amine metabolic process GO:0044106 38 0.014
regulation of lymphocyte proliferation GO:0050670 26 0.014
nucleotide metabolic process GO:0009117 279 0.014
positive regulation of phagocytosis engulfment GO:0060100 4 0.014
immune effector process GO:0002252 53 0.014
cholesterol homeostasis GO:0042632 3 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
regulation of cell proliferation GO:0042127 359 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
cellular response to cgmp GO:0071321 2 0.014
vascular process in circulatory system GO:0003018 96 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
positive regulation of tolerance induction to nonself antigen GO:0002657 1 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.013
calcium ion transport GO:0006816 131 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
protein transport GO:0015031 132 0.013
regulation of locomotion GO:0040012 148 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
positive regulation of locomotion GO:0040017 102 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
response to antibiotic GO:0046677 39 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
lipid metabolic process GO:0006629 283 0.013
gamete generation GO:0007276 124 0.013
response to virus GO:0009615 17 0.013
regulation of lymphocyte migration GO:2000401 1 0.013
sequestering of metal ion GO:0051238 9 0.013
negative regulation of immune response GO:0050777 15 0.013
regulation of neuron differentiation GO:0045664 208 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
intracellular transport GO:0046907 185 0.013
response to toxic substance GO:0009636 133 0.013
response to interleukin 1 GO:0070555 55 0.013
regulation of protein metabolic process GO:0051246 289 0.013
detection of chemical stimulus GO:0009593 10 0.013
cellular response to organic cyclic compound GO:0071407 202 0.012
actin filament based process GO:0030029 86 0.012
regulation of response to stress GO:0080134 126 0.012
cell adhesion GO:0007155 110 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
activation of immune response GO:0002253 26 0.012
protein oligomerization GO:0051259 191 0.012
action potential GO:0001508 54 0.012
response to oxidative stress GO:0006979 186 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
regulation of secretion by cell GO:1903530 208 0.012
organ regeneration GO:0031100 101 0.012
positive regulation of tolerance induction GO:0002645 1 0.012
behavior GO:0007610 205 0.012
synaptic transmission GO:0007268 235 0.012
calcium ion homeostasis GO:0055074 162 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
intestinal absorption GO:0050892 3 0.012
positive regulation of developmental process GO:0051094 283 0.012
positive regulation of cell death GO:0010942 184 0.012
cellular response to lipid GO:0071396 201 0.012
organic acid transport GO:0015849 116 0.012
regulation of anatomical structure size GO:0090066 135 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
t cell proliferation GO:0042098 19 0.012
positive regulation of cell migration GO:0030335 96 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
regulation of sodium ion transport GO:0002028 21 0.012
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.012
monocarboxylic acid transport GO:0015718 52 0.012
divalent inorganic cation transport GO:0072511 134 0.011
positive regulation of chemotaxis GO:0050921 23 0.011
homeostatic process GO:0042592 331 0.011
sequestering of calcium ion GO:0051208 8 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
cellular component biogenesis GO:0044085 368 0.011
lymphocyte migration GO:0072676 3 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
regulation of peptide transport GO:0090087 87 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
negative regulation of viral process GO:0048525 4 0.011
cardiac conduction GO:0061337 2 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
brain development GO:0007420 247 0.011
sensory perception of bitter taste GO:0050913 4 0.011
macromolecule localization GO:0033036 252 0.011
positive regulation of endothelial cell differentiation GO:0045603 2 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
response to wounding GO:0009611 254 0.011
regulation of rna metabolic process GO:0051252 391 0.011
cellular response to extracellular stimulus GO:0031668 73 0.010
cell cell junction organization GO:0045216 20 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.010
response to cytokine GO:0034097 215 0.010
regulation of lymphocyte activation GO:0051249 34 0.010
regulation of synaptic transmission GO:0050804 141 0.010
leukocyte differentiation GO:0002521 30 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
neurological system process GO:0050877 219 0.010
spindle organization GO:0007051 2 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
cellular response to hormone stimulus GO:0032870 247 0.010

Rt1.aa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
sensory system disease DOID:0050155 0 0.038
musculoskeletal system disease DOID:17 0 0.030
cardiovascular system disease DOID:1287 0 0.026
eye and adnexa disease DOID:1492 0 0.024
eye disease DOID:5614 0 0.024
combined t cell and b cell immunodeficiency DOID:628 0 0.012
severe combined immunodeficiency DOID:627 0 0.012
primary immunodeficiency disease DOID:612 0 0.012
immune system disease DOID:2914 0 0.012