Rattus norvegicus

0 known processes

Rtn1

reticulon 1

(Aliases: Nsp)

Rtn1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.282
regulation of cell development GO:0060284 263 0.234
protein complex biogenesis GO:0070271 263 0.188
negative regulation of nervous system development GO:0051961 79 0.168
cellular component biogenesis GO:0044085 368 0.164
cellular component assembly GO:0022607 360 0.159
macromolecular complex assembly GO:0065003 273 0.155
regulation of neuron differentiation GO:0045664 208 0.152
neuron development GO:0048666 286 0.137
locomotion GO:0040011 237 0.136
macromolecular complex subunit organization GO:0043933 339 0.136
positive regulation of neuron projection development GO:0010976 99 0.133
regulation of nervous system development GO:0051960 264 0.125
regulation of multicellular organismal development GO:2000026 376 0.124
regulation of cell differentiation GO:0045595 320 0.116
negative regulation of multicellular organismal process GO:0051241 203 0.109
regulation of cellular component organization GO:0051128 368 0.108
carboxylic acid metabolic process GO:0019752 289 0.107
regulation of neurogenesis GO:0050767 247 0.106
eye morphogenesis GO:0048592 4 0.102
protein complex subunit organization GO:0071822 302 0.102
neuron projection development GO:0031175 273 0.099
oxoacid metabolic process GO:0043436 290 0.099
organic acid metabolic process GO:0006082 292 0.095
regulation of protein metabolic process GO:0051246 289 0.094
cell projection organization GO:0030030 302 0.087
regulation of neuron projection development GO:0010975 161 0.086
protein complex assembly GO:0006461 263 0.079
cell migration GO:0016477 197 0.077
anatomical structure morphogenesis GO:0009653 298 0.077
axon development GO:0061564 96 0.076
negative regulation of cell development GO:0010721 82 0.073
negative regulation of developmental process GO:0051093 125 0.072
cellular component movement GO:0006928 248 0.072
response to wounding GO:0009611 254 0.068
vesicle mediated transport GO:0016192 181 0.068
organic substance catabolic process GO:1901575 316 0.063
regulation of locomotion GO:0040012 148 0.061
negative regulation of cell differentiation GO:0045596 99 0.060
negative regulation of metabolic process GO:0009892 331 0.059
positive regulation of nervous system development GO:0051962 178 0.058
regulation of cell projection organization GO:0031344 175 0.057
organelle organization GO:0006996 266 0.056
regulation of cell migration GO:0030334 128 0.056
positive regulation of neurogenesis GO:0050769 165 0.053
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.053
cell projection morphogenesis GO:0048858 123 0.052
cellular catabolic process GO:0044248 295 0.052
protein oligomerization GO:0051259 191 0.050
central nervous system development GO:0007417 311 0.050
single organism behavior GO:0044708 130 0.049
cell cell signaling GO:0007267 335 0.048
positive regulation of developmental process GO:0051094 283 0.046
behavior GO:0007610 205 0.045
cellular response to endogenous stimulus GO:0071495 377 0.045
secretion GO:0046903 307 0.044
cation transport GO:0006812 382 0.044
neurological system process GO:0050877 219 0.042
single organism organelle organization GO:1902589 180 0.041
cell motility GO:0048870 202 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.041
cell morphogenesis GO:0000902 142 0.040
positive regulation of cell differentiation GO:0045597 217 0.040
cytoskeleton organization GO:0007010 111 0.040
neuron projection morphogenesis GO:0048812 122 0.039
heterocycle catabolic process GO:0046700 167 0.039
positive regulation of multicellular organismal process GO:0051240 387 0.039
divalent metal ion transport GO:0070838 132 0.039
negative regulation of cellular metabolic process GO:0031324 281 0.038
localization of cell GO:0051674 202 0.038
regulation of rna metabolic process GO:0051252 391 0.038
positive regulation of signaling GO:0023056 270 0.038
cellular response to growth factor stimulus GO:0071363 162 0.038
synaptic transmission GO:0007268 235 0.037
rna metabolic process GO:0016070 406 0.037
learning or memory GO:0007611 90 0.036
intracellular signal transduction GO:0035556 314 0.036
response to growth factor GO:0070848 189 0.036
response to corticosteroid GO:0031960 235 0.036
cognition GO:0050890 92 0.036
nucleoside phosphate metabolic process GO:0006753 283 0.036
catabolic process GO:0009056 351 0.035
single organism catabolic process GO:0044712 283 0.035
synaptic vesicle transport GO:0048489 23 0.034
positive regulation of cell projection organization GO:0031346 111 0.034
response to inorganic substance GO:0010035 377 0.034
chemical homeostasis GO:0048878 292 0.033
nucleotide catabolic process GO:0009166 139 0.033
ion homeostasis GO:0050801 212 0.033
cellular amino acid metabolic process GO:0006520 107 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
positive regulation of neuron differentiation GO:0045666 126 0.032
response to cytokine GO:0034097 215 0.032
regulation of signal transduction GO:0009966 318 0.032
cellular ketone metabolic process GO:0042180 51 0.032
monocarboxylic acid metabolic process GO:0032787 152 0.031
positive regulation of cellular component organization GO:0051130 200 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
ras protein signal transduction GO:0007265 29 0.031
endocytosis GO:0006897 84 0.030
oxidation reduction process GO:0055114 304 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
nucleoside metabolic process GO:0009116 179 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.028
actin filament based process GO:0030029 86 0.028
cell morphogenesis involved in differentiation GO:0000904 119 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
small gtpase mediated signal transduction GO:0007264 36 0.027
purine containing compound metabolic process GO:0072521 253 0.027
regulation of cell motility GO:2000145 131 0.027
positive regulation of cell development GO:0010720 176 0.027
multi organism reproductive process GO:0044703 262 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
lipid metabolic process GO:0006629 283 0.027
secretion by cell GO:0032940 248 0.026
synaptic growth at neuromuscular junction GO:0051124 1 0.026
regulation of cellular localization GO:0060341 263 0.026
pyrimidine nucleobase catabolic process GO:0006208 3 0.026
negative regulation of neurogenesis GO:0050768 78 0.026
cellular amine metabolic process GO:0044106 38 0.025
rna biosynthetic process GO:0032774 380 0.025
protein phosphorylation GO:0006468 345 0.025
cellular component morphogenesis GO:0032989 155 0.025
nucleic acid templated transcription GO:0097659 379 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.024
cellular divalent inorganic cation homeostasis GO:0072503 162 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
eye photoreceptor cell development GO:0042462 1 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
organophosphate metabolic process GO:0019637 370 0.023
metal ion transport GO:0030001 289 0.023
regeneration GO:0031099 163 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
positive regulation of gene expression GO:0010628 244 0.023
positive regulation of rna metabolic process GO:0051254 203 0.022
multicellular organism reproduction GO:0032504 233 0.022
amine metabolic process GO:0009308 38 0.022
cellular lipid metabolic process GO:0044255 208 0.022
response to metal ion GO:0010038 253 0.022
reproduction GO:0000003 245 0.022
response to extracellular stimulus GO:0009991 380 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
exocytosis GO:0006887 60 0.021
axis specification GO:0009798 4 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
response to purine containing compound GO:0014074 126 0.020
negative regulation of gene expression GO:0010629 199 0.020
regulation of secretion GO:0051046 224 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
negative regulation of cellular amide metabolic process GO:0034249 1 0.020
reproductive process GO:0022414 372 0.020
positive regulation of fatty acid beta oxidation GO:0032000 4 0.019
actin crosslink formation GO:0051764 3 0.019
cellular cation homeostasis GO:0030003 180 0.019
regulation of secretion by cell GO:1903530 208 0.019
response to nutrient GO:0007584 248 0.019
programmed cell death GO:0012501 392 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
response to peptide GO:1901652 292 0.019
male mating behavior GO:0060179 3 0.019
ribonucleoside metabolic process GO:0009119 174 0.018
intracellular transport GO:0046907 185 0.018
negative regulation of neuron projection development GO:0010977 46 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
response to radiation GO:0009314 137 0.018
regulation of ion transport GO:0043269 245 0.018
feeding behavior GO:0007631 53 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
response to ethanol GO:0045471 162 0.018
gamete generation GO:0007276 124 0.017
vesicle localization GO:0051648 33 0.017
homeostatic process GO:0042592 331 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to peptide hormone GO:0043434 278 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
ion transmembrane transport GO:0034220 365 0.017
aging GO:0007568 241 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
regulation of cellular component biogenesis GO:0044087 86 0.016
response to camp GO:0051591 91 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
single organism intracellular transport GO:1902582 166 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
regulation of transcription dna templated GO:0006355 374 0.016
regulation of catalytic activity GO:0050790 304 0.016
response to acid chemical GO:0001101 222 0.016
cellular ion homeostasis GO:0006873 184 0.016
negative regulation of neuron differentiation GO:0045665 62 0.016
embryonic pattern specification GO:0009880 1 0.016
cytoskeleton dependent cytokinesis GO:0061640 2 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
peptidyl amino acid modification GO:0018193 126 0.016
potassium ion transport GO:0006813 97 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
proteolysis GO:0006508 175 0.016
adult locomotory behavior GO:0008344 4 0.016
immune system process GO:0002376 204 0.016
transcription dna templated GO:0006351 377 0.016
cellular homeostasis GO:0019725 252 0.015
protein heterooligomerization GO:0051291 89 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
response to bacterium GO:0009617 200 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
regulation of programmed cell death GO:0043067 341 0.015
peptide metabolic process GO:0006518 32 0.015
response to glucocorticoid GO:0051384 223 0.015
sexual reproduction GO:0019953 148 0.015
single organism biosynthetic process GO:0044711 342 0.015
response to lipopolysaccharide GO:0032496 191 0.015
gliogenesis GO:0042063 93 0.015
axon choice point recognition GO:0016198 2 0.015
meiotic cell cycle process GO:1903046 3 0.015
cation homeostasis GO:0055080 195 0.015
nucleotide metabolic process GO:0009117 279 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
regulation of molecular function GO:0065009 398 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
response to carbohydrate GO:0009743 183 0.015
regulation of anatomical structure size GO:0090066 135 0.015
response to oxidative stress GO:0006979 186 0.015
positive regulation of transport GO:0051050 245 0.014
positive regulation of cell death GO:0010942 184 0.014
organophosphate catabolic process GO:0046434 148 0.014
axon cargo transport GO:0008088 1 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
response to other organism GO:0051707 220 0.014
response to hypoxia GO:0001666 231 0.014
response to biotic stimulus GO:0009607 226 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
olfactory learning GO:0008355 1 0.014
protein transport GO:0015031 132 0.014
response to nutrient levels GO:0031667 370 0.014
fatty acid metabolic process GO:0006631 99 0.014
brain development GO:0007420 247 0.014
protein autophosphorylation GO:0046777 66 0.014
response to monosaccharide GO:0034284 159 0.014
actin cytoskeleton organization GO:0030036 73 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
negative regulation of cell death GO:0060548 229 0.014
positive regulation of cell communication GO:0010647 271 0.013
regulation of synaptic transmission GO:0050804 141 0.013
response to oxygen levels GO:0070482 265 0.013
cellular chemical homeostasis GO:0055082 247 0.013
synaptic vesicle priming GO:0016082 4 0.013
positive regulation of cellular component biogenesis GO:0044089 55 0.013
developmental growth GO:0048589 100 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
regulation of cell proliferation GO:0042127 359 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
positive regulation of secretion GO:0051047 140 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
lipid biosynthetic process GO:0008610 128 0.013
embryonic axis specification GO:0000578 1 0.013
regulation of hormone levels GO:0010817 187 0.013
apoptotic process GO:0006915 381 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
macromolecule localization GO:0033036 252 0.013
transmission of nerve impulse GO:0019226 42 0.013
cellular amide metabolic process GO:0043603 44 0.013
cellular response to nitrogen compound GO:1901699 210 0.012
transmembrane transport GO:0055085 412 0.012
male gamete generation GO:0048232 99 0.012
response to vitamin GO:0033273 131 0.012
regulation of cellular component movement GO:0051270 150 0.012
organelle localization GO:0051640 55 0.012
generation of precursor metabolites and energy GO:0006091 62 0.012
lipid oxidation GO:0034440 30 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
response to amphetamine GO:0001975 25 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
salivary gland morphogenesis GO:0007435 1 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
metal ion homeostasis GO:0055065 186 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
axonogenesis GO:0007409 71 0.012
cation transmembrane transport GO:0098655 263 0.012
response to cocaine GO:0042220 39 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
response to organophosphorus GO:0046683 102 0.012
divalent inorganic cation transport GO:0072511 134 0.012
regulation of small gtpase mediated signal transduction GO:0051056 48 0.012
olfactory behavior GO:0042048 2 0.012
response to estrogen GO:0043627 232 0.012
cell projection assembly GO:0030031 21 0.012
gtp metabolic process GO:0046039 72 0.012
tissue development GO:0009888 252 0.012
regulation of apoptotic process GO:0042981 335 0.012
calcium ion homeostasis GO:0055074 162 0.012
rna localization GO:0006403 4 0.012
regulation of transporter activity GO:0032409 50 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
dendrite development GO:0016358 72 0.011
regulation of growth GO:0040008 105 0.011
spermatogenesis GO:0007283 99 0.011
cellular protein complex assembly GO:0043623 44 0.011
purine containing compound catabolic process GO:0072523 138 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
cell cycle process GO:0022402 57 0.011
dendrite morphogenesis GO:0048813 43 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
protein tetramerization GO:0051262 38 0.011
head development GO:0060322 247 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.011
establishment of synaptic vesicle localization GO:0097480 23 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
regulation of hydrolase activity GO:0051336 143 0.011
regulation of gtpase activity GO:0043087 57 0.011
neuron death GO:0070997 127 0.011
memory GO:0007613 54 0.011
beta alanine metabolic process GO:0019482 3 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
cellular response to acid chemical GO:0071229 75 0.011
microtubule organizing center organization GO:0031023 1 0.011
establishment of protein localization GO:0045184 141 0.011
response to ammonium ion GO:0060359 71 0.010
cellular response to stress GO:0033554 269 0.010
single organism cellular localization GO:1902580 102 0.010
regulation of synaptic plasticity GO:0048167 70 0.010
response to axon injury GO:0048678 59 0.010
uracil metabolic process GO:0019860 3 0.010
cellular macromolecule localization GO:0070727 122 0.010
response to hexose GO:0009746 144 0.010

Rtn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
central nervous system disease DOID:331 0 0.024
epilepsy syndrome DOID:1826 0 0.013
brain disease DOID:936 0 0.013
electroclinical syndrome DOID:0050701 0 0.013
neonatal period electroclinical syndrome DOID:0050702 0 0.013