Rattus norvegicus

111 known processes

S100b

S100 calcium binding protein B

(Aliases: MGC93559,S100P)

S100b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myelination GO:0042552 39 0.579
transmission of nerve impulse GO:0019226 42 0.247
anatomical structure morphogenesis GO:0009653 298 0.231
response to metal ion GO:0010038 253 0.191
Rat
regulation of nervous system development GO:0051960 264 0.184
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.181
response to inorganic substance GO:0010035 377 0.143
Rat
inorganic cation transmembrane transport GO:0098662 202 0.135
Rat
aging GO:0007568 241 0.126
negative regulation of multicellular organismal process GO:0051241 203 0.125
regulation of cellular component organization GO:0051128 368 0.124
response to transition metal nanoparticle GO:1990267 122 0.121
cation transport GO:0006812 382 0.115
Rat
regulation of cell morphogenesis GO:0022604 77 0.114
apoptotic process GO:0006915 381 0.113
regulation of cell projection organization GO:0031344 175 0.110
regulation of cell proliferation GO:0042127 359 0.108
positive regulation of cell death GO:0010942 184 0.102
cellular response to growth factor stimulus GO:0071363 162 0.100
regulation of cell development GO:0060284 263 0.098
neurotransmitter uptake GO:0001504 3 0.095
response to molecule of bacterial origin GO:0002237 194 0.094
Rat
response to oxygen levels GO:0070482 265 0.093
neuronal action potential GO:0019228 35 0.091
regulation of cell differentiation GO:0045595 320 0.089
programmed cell death GO:0012501 392 0.089
divalent inorganic cation transport GO:0072511 134 0.086
Rat
response to ketone GO:1901654 182 0.086
response to peptide hormone GO:0043434 278 0.084
cellular cation homeostasis GO:0030003 180 0.082
regulation of apoptotic process GO:0042981 335 0.082
homeostatic process GO:0042592 331 0.080
axon ensheathment GO:0008366 40 0.080
cellular potassium ion transport GO:0071804 72 0.080
neuron projection development GO:0031175 273 0.080
response to camp GO:0051591 91 0.079
cellular response to endogenous stimulus GO:0071495 377 0.079
regulation of axonogenesis GO:0050770 37 0.078
respiratory system process GO:0003016 3 0.075
response to biotic stimulus GO:0009607 226 0.075
Rat
negative regulation of cell differentiation GO:0045596 99 0.074
regulation of neuron projection development GO:0010975 161 0.074
response to oxidative stress GO:0006979 186 0.073
regulation of anatomical structure morphogenesis GO:0022603 141 0.068
inorganic ion transmembrane transport GO:0098660 229 0.067
Rat
negative regulation of neuron differentiation GO:0045665 62 0.067
response to tumor necrosis factor GO:0034612 56 0.066
neuron apoptotic process GO:0051402 88 0.064
cell projection organization GO:0030030 302 0.064
negative regulation of neurogenesis GO:0050768 78 0.062
response to external biotic stimulus GO:0043207 221 0.061
Rat
regulation of ion transport GO:0043269 245 0.060
Rat
response to fatty acid GO:0070542 65 0.060
sodium ion transport GO:0006814 82 0.059
cellular response to hormone stimulus GO:0032870 247 0.058
cellular sodium ion homeostasis GO:0006883 4 0.058
response to acid chemical GO:0001101 222 0.058
behavior GO:0007610 205 0.057
Mouse
chemical homeostasis GO:0048878 292 0.056
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.054
regulation of membrane potential GO:0042391 110 0.053
response to cytokine GO:0034097 215 0.053
divalent inorganic cation homeostasis GO:0072507 165 0.053
response to growth factor GO:0070848 189 0.052
cell morphogenesis GO:0000902 142 0.052
regulation of neuron differentiation GO:0045664 208 0.051
tissue development GO:0009888 252 0.051
response to other organism GO:0051707 220 0.051
Rat
carboxylic acid metabolic process GO:0019752 289 0.051
cation transmembrane transport GO:0098655 263 0.051
Rat
catabolic process GO:0009056 351 0.051
divalent metal ion transport GO:0070838 132 0.051
Rat
transmembrane transport GO:0055085 412 0.051
Rat
neuron development GO:0048666 286 0.050
central nervous system development GO:0007417 311 0.047
response to carbohydrate GO:0009743 183 0.047
cellular chemical homeostasis GO:0055082 247 0.046
head development GO:0060322 247 0.046
regulation of cellular amine metabolic process GO:0033238 8 0.045
sodium ion transmembrane transport GO:0035725 67 0.045
brain development GO:0007420 247 0.045
neuron differentiation GO:0030182 368 0.045
single organism biosynthetic process GO:0044711 342 0.045
regulation of multicellular organismal development GO:2000026 376 0.044
regulation of phosphorylation GO:0042325 248 0.043
regulation of blood pressure GO:0008217 83 0.043
amine metabolic process GO:0009308 38 0.043
circulatory system development GO:0072359 134 0.042
regulation of phosphorus metabolic process GO:0051174 349 0.041
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.041
cellular ketone metabolic process GO:0042180 51 0.040
response to nutrient levels GO:0031667 370 0.040
organic acid metabolic process GO:0006082 292 0.040
response to alkaloid GO:0043279 132 0.040
response to estrogen GO:0043627 232 0.039
response to increased oxygen levels GO:0036296 45 0.038
response to purine containing compound GO:0014074 126 0.038
metal ion transport GO:0030001 289 0.037
Rat
cellular response to acid chemical GO:0071229 75 0.037
oxoacid metabolic process GO:0043436 290 0.036
cellular response to lipid GO:0071396 201 0.035
regulation of neuron apoptotic process GO:0043523 83 0.035
monovalent inorganic cation transport GO:0015672 172 0.035
single organism behavior GO:0044708 130 0.035
Mouse
nitrogen compound transport GO:0071705 229 0.035
membrane hyperpolarization GO:0060081 11 0.035
response to lead ion GO:0010288 33 0.034
regulation of molecular function GO:0065009 398 0.034
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.034
cardiovascular system development GO:0072358 134 0.033
heart morphogenesis GO:0003007 3 0.032
metal ion homeostasis GO:0055065 186 0.032
cellular homeostasis GO:0019725 252 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
cellular metal ion homeostasis GO:0006875 172 0.031
respiratory gaseous exchange GO:0007585 4 0.031
response to extracellular stimulus GO:0009991 380 0.031
cellular response to oxygen containing compound GO:1901701 386 0.031
blood circulation GO:0008015 183 0.030
regulation of protein metabolic process GO:0051246 289 0.030
regulation of respiratory gaseous exchange GO:0043576 2 0.030
cellular divalent inorganic cation homeostasis GO:0072503 162 0.030
cellular response to abiotic stimulus GO:0071214 85 0.030
response to ethanol GO:0045471 162 0.029
Rat
neuron death GO:0070997 127 0.029
response to lipopolysaccharide GO:0032496 191 0.029
Rat
positive regulation of cellular component organization GO:0051130 200 0.029
lipid metabolic process GO:0006629 283 0.029
negative regulation of metabolic process GO:0009892 331 0.029
Rat
response to vitamin GO:0033273 131 0.029
protein phosphorylation GO:0006468 345 0.028
response to hydrogen peroxide GO:0042542 89 0.028
cellular response to organic cyclic compound GO:0071407 202 0.028
negative regulation of cell proliferation GO:0008285 119 0.028
response to fluoride GO:1902617 3 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.028
Rat
cardiac muscle cell contraction GO:0086003 10 0.027
regulation of tube size GO:0035150 89 0.027
ion homeostasis GO:0050801 212 0.027
regulation of sodium ion transport GO:0002028 21 0.027
cellular amine metabolic process GO:0044106 38 0.027
cellular component movement GO:0006928 248 0.027
cellular response to external stimulus GO:0071496 118 0.027
taxis GO:0042330 67 0.026
axonogenesis GO:0007409 71 0.026
response to organophosphorus GO:0046683 102 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
ion transmembrane transport GO:0034220 365 0.026
Rat
organic hydroxy compound transport GO:0015850 77 0.026
multicellular organism growth GO:0035264 1 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
defense response GO:0006952 194 0.025
Rat
regulation of phosphate metabolic process GO:0019220 349 0.025
striated muscle tissue development GO:0014706 58 0.025
regulation of homotypic cell cell adhesion GO:0034110 4 0.025
ensheathment of neurons GO:0007272 40 0.025
positive regulation of nervous system development GO:0051962 178 0.024
cellular response to stress GO:0033554 269 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
regulation of programmed cell death GO:0043067 341 0.024
response to corticosteroid GO:0031960 235 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
Rat
response to reactive oxygen species GO:0000302 120 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
response to bacterium GO:0009617 200 0.024
Rat
negative regulation of cell development GO:0010721 82 0.024
regulation of neuron death GO:1901214 115 0.024
response to peptide GO:1901652 292 0.024
cellular potassium ion homeostasis GO:0030007 1 0.024
regulation of calcium ion transmembrane transport GO:1903169 18 0.024
Rat
positive regulation of molecular function GO:0044093 230 0.023
Rat
cellular lipid metabolic process GO:0044255 208 0.023
cellular response to cytokine stimulus GO:0071345 127 0.023
cellular response to mechanical stimulus GO:0071260 48 0.023
response to nutrient GO:0007584 248 0.023
response to toxic substance GO:0009636 133 0.023
calcium ion homeostasis GO:0055074 162 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
adult locomotory behavior GO:0008344 4 0.023
positive regulation of apoptotic process GO:0043065 154 0.023
regulation of calcium ion transport GO:0051924 77 0.023
Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
secretion GO:0046903 307 0.022
regeneration GO:0031099 163 0.022
response to nicotine GO:0035094 51 0.022
response to zinc ion GO:0010043 39 0.022
Rat
reproductive process GO:0022414 372 0.022
regulation of ion transmembrane transport GO:0034765 121 0.021
Rat
cell motility GO:0048870 202 0.021
negative regulation of nervous system development GO:0051961 79 0.021
positive regulation of developmental process GO:0051094 283 0.021
regulation of respiratory system process GO:0044065 1 0.021
cellular response to peptide hormone stimulus GO:0071375 120 0.021
response to glucocorticoid GO:0051384 223 0.021
positive regulation of cell projection organization GO:0031346 111 0.021
organ morphogenesis GO:0009887 75 0.021
positive regulation of cell development GO:0010720 176 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
response to hypoxia GO:0001666 231 0.021
negative regulation of protein metabolic process GO:0051248 114 0.020
multi organism reproductive process GO:0044703 262 0.020
regulation of metal ion transport GO:0010959 118 0.020
Rat
multicellular organismal signaling GO:0035637 44 0.020
negative regulation of transport GO:0051051 136 0.020
regulation of anatomical structure size GO:0090066 135 0.020
vasoconstriction GO:0042310 54 0.020
response to estradiol GO:0032355 164 0.020
muscle tissue development GO:0060537 58 0.020
positive regulation of fatty acid beta oxidation GO:0032000 4 0.020
reproductive system development GO:0061458 128 0.019
regulation of neurogenesis GO:0050767 247 0.019
regulation of cell motility GO:2000145 131 0.019
heart development GO:0007507 72 0.019
regulation of transporter activity GO:0032409 50 0.019
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
dna metabolic process GO:0006259 96 0.019
response to monosaccharide GO:0034284 159 0.019
negative regulation of molecular function GO:0044092 133 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
localization of cell GO:0051674 202 0.019
negative regulation of phosphorus metabolic process GO:0010563 80 0.018
response to radiation GO:0009314 137 0.018
positive regulation of signaling GO:0023056 270 0.018
cellular response to oxidative stress GO:0034599 76 0.018
lipid transport GO:0006869 61 0.018
organophosphate metabolic process GO:0019637 370 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
regulation of protein modification process GO:0031399 194 0.018
developmental growth GO:0048589 100 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.017
renal system process GO:0003014 40 0.017
cell type specific apoptotic process GO:0097285 134 0.017
eye morphogenesis GO:0048592 4 0.017
locomotion GO:0040011 237 0.017
negative regulation of developmental process GO:0051093 125 0.017
protein complex biogenesis GO:0070271 263 0.016
reproductive structure development GO:0048608 128 0.016
anion transport GO:0006820 178 0.016
regulation of blood vessel size GO:0050880 89 0.016
pyruvate metabolic process GO:0006090 27 0.016
epithelium development GO:0060429 96 0.016
learning or memory GO:0007611 90 0.016
Mouse
positive regulation of neuron projection development GO:0010976 99 0.016
macromolecule localization GO:0033036 252 0.016
regulation of cellular component movement GO:0051270 150 0.016
neuron projection morphogenesis GO:0048812 122 0.016
positive regulation of cell motility GO:2000147 97 0.015
negative regulation of signaling GO:0023057 157 0.015
response to mechanical stimulus GO:0009612 134 0.015
gliogenesis GO:0042063 93 0.015
response to progesterone GO:0032570 48 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
potassium ion transmembrane transport GO:0071805 71 0.015
extracellular matrix constituent secretion GO:0070278 4 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
positive regulation of cell communication GO:0010647 271 0.015
intracellular signal transduction GO:0035556 314 0.015
axis specification GO:0009798 4 0.015
response to hexose GO:0009746 144 0.015
cellular catabolic process GO:0044248 295 0.015
regulation of growth GO:0040008 105 0.015
regulation of lipid metabolic process GO:0019216 68 0.015
chemotaxis GO:0006935 66 0.015
diaphragm contraction GO:0002086 2 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
multi multicellular organism process GO:0044706 138 0.014
small molecule catabolic process GO:0044282 59 0.014
negative regulation of cell projection organization GO:0031345 50 0.014
macromolecular complex assembly GO:0065003 273 0.014
organic substance catabolic process GO:1901575 316 0.014
negative regulation of cell communication GO:0010648 158 0.014
regulation of cell growth GO:0001558 85 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
growth GO:0040007 165 0.014
regulation of transferase activity GO:0051338 123 0.014
regulation of nucleic acid templated transcription GO:1903506 380 0.014
Rat
cellular component biogenesis GO:0044085 368 0.014
proteolysis GO:0006508 175 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
response to hyperoxia GO:0055093 45 0.014
positive regulation of neuron differentiation GO:0045666 126 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
negative regulation of epithelial cell proliferation GO:0050680 16 0.013
potassium ion homeostasis GO:0055075 2 0.013
skeletal muscle tissue development GO:0007519 31 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
regulation of system process GO:0044057 208 0.013
negative regulation of sodium ion transport GO:0010766 2 0.013
ras protein signal transduction GO:0007265 29 0.013
protein homooligomerization GO:0051260 91 0.013
negative regulation of neuron projection development GO:0010977 46 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
response to wounding GO:0009611 254 0.013
Rat
potassium ion transport GO:0006813 97 0.013
rhythmic process GO:0048511 156 0.013
regulation of signal transduction GO:0009966 318 0.013
negative regulation of cell death GO:0060548 229 0.013
protein localization GO:0008104 191 0.013
gamete generation GO:0007276 124 0.013
reproduction GO:0000003 245 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.013
regulation of cell migration GO:0030334 128 0.013
protein complex assembly GO:0006461 263 0.013
cellular ion homeostasis GO:0006873 184 0.013
sex differentiation GO:0007548 113 0.013
male gamete generation GO:0048232 99 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
intermediate filament bundle assembly GO:0045110 1 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.012
intracellular transport GO:0046907 185 0.012
response to glucose GO:0009749 136 0.012
response to fibroblast growth factor GO:0071774 29 0.012
cell cycle checkpoint GO:0000075 2 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
response to ionizing radiation GO:0010212 59 0.012
inflammatory response GO:0006954 150 0.012
Rat
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
response to ammonium ion GO:0060359 71 0.012
response to corticosterone GO:0051412 40 0.012
response to genistein GO:0033595 4 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
regulation of response to wounding GO:1903034 69 0.012
involuntary skeletal muscle contraction GO:0003011 2 0.012
development of primary sexual characteristics GO:0045137 107 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
multicellular organism reproduction GO:0032504 233 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
vascular process in circulatory system GO:0003018 96 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
fatty acid metabolic process GO:0006631 99 0.012
cellular macromolecule localization GO:0070727 122 0.012
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.012
negative regulation of phosphorylation GO:0042326 57 0.012
female pregnancy GO:0007565 122 0.012
schwann cell migration GO:0036135 2 0.011
positive regulation of protein modification process GO:0031401 142 0.011
protein processing GO:0016485 68 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
regulation of response to external stimulus GO:0032101 106 0.011
spermatogenesis GO:0007283 99 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
positive regulation of transport GO:0051050 245 0.011
Rat
regulation of membrane repolarization GO:0060306 1 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
regulation of developmental growth GO:0048638 45 0.011
epithelial cell proliferation GO:0050673 54 0.011
regulation of defense response GO:0031347 68 0.011
response to decreased oxygen levels GO:0036293 237 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
fatty acid catabolic process GO:0009062 26 0.011
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.011
negative regulation of endothelial cell proliferation GO:0001937 5 0.011
regulation of ion homeostasis GO:2000021 63 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
glycerolipid metabolic process GO:0046486 67 0.011
motor neuron axon guidance GO:0008045 1 0.011
neural crest cell differentiation GO:0014033 2 0.011
dna integrity checkpoint GO:0031570 2 0.010
action potential GO:0001508 54 0.010
mapk cascade GO:0000165 140 0.010
organ regeneration GO:0031100 101 0.010
response to amino acid GO:0043200 75 0.010
embryonic cranial skeleton morphogenesis GO:0048701 2 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
small molecule biosynthetic process GO:0044283 124 0.010
catenin import into nucleus GO:0035411 1 0.010
response to retinoic acid GO:0032526 63 0.010
neurological system process GO:0050877 219 0.010
Mouse
lipid biosynthetic process GO:0008610 128 0.010
glucose homeostasis GO:0042593 75 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.010
cell part morphogenesis GO:0032990 123 0.010
carboxylic acid catabolic process GO:0046395 49 0.010
positive regulation of hormone secretion GO:0046887 65 0.010
regulation of vasoconstriction GO:0019229 44 0.010
positive regulation of fibroblast proliferation GO:0048146 15 0.010

S100b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.081
disease of anatomical entity DOID:7 0 0.081
brain disease DOID:936 0 0.051
central nervous system disease DOID:331 0 0.051
cerebral degeneration DOID:1443 0 0.043
musculoskeletal system disease DOID:17 0 0.032
leukodystrophy DOID:10579 0 0.016
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
bone disease DOID:0080001 0 0.011
connective tissue disease DOID:65 0 0.011