Rattus norvegicus

0 known processes

Sash3

SAM and SH3 domain containing 3

(Aliases: MGC189506,RGD1560293)

Sash3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune response activating signal transduction GO:0002757 15 0.318
immune system process GO:0002376 204 0.216
biological adhesion GO:0022610 110 0.207
cellular component biogenesis GO:0044085 368 0.175
regulation of immune system process GO:0002682 123 0.149
t cell receptor signaling pathway GO:0050852 1 0.130
leukocyte cell cell adhesion GO:0007159 4 0.113
oxoacid metabolic process GO:0043436 290 0.112
rna biosynthetic process GO:0032774 380 0.107
regulation of protein phosphorylation GO:0001932 183 0.098
cell migration GO:0016477 197 0.096
regulation of molecular function GO:0065009 398 0.093
cellular component assembly GO:0022607 360 0.091
cell motility GO:0048870 202 0.086
positive regulation of secretion GO:0051047 140 0.084
antigen receptor mediated signaling pathway GO:0050851 1 0.083
intracellular signal transduction GO:0035556 314 0.078
response to biotic stimulus GO:0009607 226 0.073
regulation of phosphate metabolic process GO:0019220 349 0.073
immune response regulating signaling pathway GO:0002764 19 0.071
protein complex subunit organization GO:0071822 302 0.070
negative regulation of metabolic process GO:0009892 331 0.068
regulation of signal transduction GO:0009966 318 0.066
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.066
macromolecular complex assembly GO:0065003 273 0.065
positive regulation of biosynthetic process GO:0009891 319 0.061
organic acid metabolic process GO:0006082 292 0.060
localization of cell GO:0051674 202 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.058
response to wounding GO:0009611 254 0.057
immune response GO:0006955 104 0.057
regulation of cellular component organization GO:0051128 368 0.057
synaptic growth at neuromuscular junction GO:0051124 1 0.057
secretion GO:0046903 307 0.057
carboxylic acid metabolic process GO:0019752 289 0.057
cellular carbohydrate metabolic process GO:0044262 72 0.056
organophosphate metabolic process GO:0019637 370 0.055
protein phosphorylation GO:0006468 345 0.055
nucleoside phosphate catabolic process GO:1901292 140 0.054
cellular catabolic process GO:0044248 295 0.053
regulation of locomotion GO:0040012 148 0.053
positive regulation of protein metabolic process GO:0051247 178 0.052
regulation of nucleic acid templated transcription GO:1903506 380 0.052
regulation of cell proliferation GO:0042127 359 0.052
regulation of rna metabolic process GO:0051252 391 0.052
regulation of protein metabolic process GO:0051246 289 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.051
regulation of cellular amino acid metabolic process GO:0006521 2 0.050
protein complex biogenesis GO:0070271 263 0.049
vesicle mediated transport GO:0016192 181 0.048
regulation of phosphorylation GO:0042325 248 0.048
regulation of programmed cell death GO:0043067 341 0.048
exocytosis GO:0006887 60 0.046
regulation of cellular amine metabolic process GO:0033238 8 0.045
regulation of cellular ketone metabolic process GO:0010565 27 0.045
cell activation GO:0001775 97 0.045
transcription dna templated GO:0006351 377 0.045
regulation of transcription dna templated GO:0006355 374 0.045
cellular amino acid metabolic process GO:0006520 107 0.044
single organism biosynthetic process GO:0044711 342 0.044
protein complex assembly GO:0006461 263 0.044
immune response activating cell surface receptor signaling pathway GO:0002429 6 0.043
positive regulation of transport GO:0051050 245 0.043
peptidyl tyrosine phosphorylation GO:0018108 72 0.043
amine metabolic process GO:0009308 38 0.042
fc receptor mediated stimulatory signaling pathway GO:0002431 3 0.041
multi organism reproductive process GO:0044703 262 0.041
cellular amine metabolic process GO:0044106 38 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.040
anatomical structure morphogenesis GO:0009653 298 0.040
regulation of hydrolase activity GO:0051336 143 0.039
rna metabolic process GO:0016070 406 0.038
positive regulation of developmental process GO:0051094 283 0.038
single organism catabolic process GO:0044712 283 0.038
wound healing GO:0042060 122 0.037
positive regulation of response to stimulus GO:0048584 285 0.037
positive regulation of cell proliferation GO:0008284 249 0.037
regulation of apoptotic process GO:0042981 335 0.037
positive regulation of phosphorus metabolic process GO:0010562 262 0.036
regulation of neurogenesis GO:0050767 247 0.035
cellular ketone metabolic process GO:0042180 51 0.035
protein localization GO:0008104 191 0.035
response to growth factor GO:0070848 189 0.035
positive regulation of cellular protein metabolic process GO:0032270 167 0.035
glycosyl compound catabolic process GO:1901658 126 0.035
catabolic process GO:0009056 351 0.034
regulation of rna biosynthetic process GO:2001141 381 0.034
negative regulation of cell communication GO:0010648 158 0.033
lymphocyte activation GO:0046649 43 0.032
response to extracellular stimulus GO:0009991 380 0.032
feeding behavior GO:0007631 53 0.032
positive regulation of mononuclear cell proliferation GO:0032946 20 0.032
regulation of cell differentiation GO:0045595 320 0.032
g protein coupled receptor signaling pathway GO:0007186 242 0.032
activation of immune response GO:0002253 26 0.032
regulation of secretion GO:0051046 224 0.032
multicellular organismal reproductive process GO:0048609 233 0.031
ribonucleoside triphosphate metabolic process GO:0009199 141 0.031
regulation of secretion by cell GO:1903530 208 0.031
secretion by cell GO:0032940 248 0.031
macromolecular complex subunit organization GO:0043933 339 0.031
single organism reproductive process GO:0044702 297 0.030
ion homeostasis GO:0050801 212 0.030
positive regulation of immunoglobulin production GO:0002639 4 0.029
protein maturation GO:0051604 68 0.029
regulation of cellular component biogenesis GO:0044087 86 0.029
negative regulation of signal transduction GO:0009968 83 0.029
regulation of neuron death GO:1901214 115 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
regulation of catalytic activity GO:0050790 304 0.028
single organism intracellular transport GO:1902582 166 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
cytoskeleton organization GO:0007010 111 0.028
organonitrogen compound catabolic process GO:1901565 179 0.028
positive regulation of cell death GO:0010942 184 0.028
positive regulation of cellular component organization GO:0051130 200 0.028
regulation of intracellular signal transduction GO:1902531 218 0.027
positive regulation of phosphorylation GO:0042327 177 0.027
cellular response to external stimulus GO:0071496 118 0.027
transmembrane transport GO:0055085 412 0.026
reproduction GO:0000003 245 0.026
proteolysis GO:0006508 175 0.026
dephosphorylation GO:0016311 98 0.026
programmed cell death GO:0012501 392 0.026
nucleic acid templated transcription GO:0097659 379 0.025
neuron death GO:0070997 127 0.025
multicellular organism reproduction GO:0032504 233 0.025
salivary gland development GO:0007431 3 0.025
response to nutrient levels GO:0031667 370 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
regulation of cellular localization GO:0060341 263 0.025
response to inorganic substance GO:0010035 377 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
positive regulation of leukocyte activation GO:0002696 30 0.024
negative regulation of signaling GO:0023057 157 0.024
positive regulation of molecular function GO:0044093 230 0.024
nitrogen compound transport GO:0071705 229 0.024
intracellular transport GO:0046907 185 0.024
cellular component movement GO:0006928 248 0.024
ribonucleotide metabolic process GO:0009259 231 0.023
regulation of mononuclear cell proliferation GO:0032944 26 0.023
positive regulation of secretion by cell GO:1903532 128 0.023
cation homeostasis GO:0055080 195 0.023
small molecule biosynthetic process GO:0044283 124 0.023
response to carbohydrate GO:0009743 183 0.023
positive regulation of protein modification process GO:0031401 142 0.023
reproductive process GO:0022414 372 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
regulation of leukocyte activation GO:0002694 45 0.023
cardiovascular system development GO:0072358 134 0.023
immune effector process GO:0002252 53 0.023
cell projection organization GO:0030030 302 0.022
cell adhesion GO:0007155 110 0.022
erythrocyte differentiation GO:0030218 1 0.022
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 3 0.022
actin filament based process GO:0030029 86 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
peptidyl tyrosine modification GO:0018212 72 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
negative regulation of response to stimulus GO:0048585 155 0.022
regulation of cell migration GO:0030334 128 0.022
homeostatic process GO:0042592 331 0.022
defense response GO:0006952 194 0.022
response to radiation GO:0009314 137 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
regulation of mapk cascade GO:0043408 116 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
single organism organelle organization GO:1902589 180 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
single organismal cell cell adhesion GO:0016337 42 0.020
regulation of dna metabolic process GO:0051052 60 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.020
protein dephosphorylation GO:0006470 38 0.020
neuron differentiation GO:0030182 368 0.020
response to reactive oxygen species GO:0000302 120 0.020
cellular lipid metabolic process GO:0044255 208 0.020
positive regulation of cell differentiation GO:0045597 217 0.019
carbohydrate metabolic process GO:0005975 130 0.019
response to external biotic stimulus GO:0043207 221 0.019
organic substance catabolic process GO:1901575 316 0.019
cellular macromolecular complex assembly GO:0034622 58 0.019
negative regulation of gene expression GO:0010629 199 0.019
glycerolipid metabolic process GO:0046486 67 0.019
cellular homeostasis GO:0019725 252 0.018
cell type specific apoptotic process GO:0097285 134 0.018
sequestering of calcium ion GO:0051208 8 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
cellular protein complex assembly GO:0043623 44 0.018
positive regulation of signaling GO:0023056 270 0.018
central nervous system development GO:0007417 311 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
cellular ion homeostasis GO:0006873 184 0.018
nucleoside metabolic process GO:0009116 179 0.018
negative regulation of molecular function GO:0044092 133 0.018
nucleoside catabolic process GO:0009164 126 0.018
negative regulation of adherens junction organization GO:1903392 2 0.018
maintenance of location GO:0051235 17 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
ribonucleoside catabolic process GO:0042454 126 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
protein oligomerization GO:0051259 191 0.017
spindle organization GO:0007051 2 0.017
apoptotic process GO:0006915 381 0.017
positive regulation of gamma delta t cell activation GO:0046645 1 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
cellular protein localization GO:0034613 122 0.017
heterocycle catabolic process GO:0046700 167 0.017
protein processing GO:0016485 68 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
ribonucleotide catabolic process GO:0009261 136 0.017
positive regulation of dna metabolic process GO:0051054 39 0.017
negative regulation of phosphate metabolic process GO:0045936 80 0.017
regulation of hormone levels GO:0010817 187 0.017
mapk cascade GO:0000165 140 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.016
negative regulation of cell death GO:0060548 229 0.016
anatomical structure formation involved in morphogenesis GO:0048646 83 0.016
negative regulation of innate immune response GO:0045824 4 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
erbb signaling pathway GO:0038127 23 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
lipid metabolic process GO:0006629 283 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
leukocyte migration GO:0050900 38 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
regeneration GO:0031099 163 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
single organism membrane organization GO:0044802 74 0.016
cellular response to extracellular stimulus GO:0031668 73 0.016
signal release GO:0023061 145 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.016
regulation of cell motility GO:2000145 131 0.016
response to other organism GO:0051707 220 0.016
dna metabolic process GO:0006259 96 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
motor neuron axon guidance GO:0008045 1 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
response to mechanical stimulus GO:0009612 134 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
nucleotide catabolic process GO:0009166 139 0.015
brain development GO:0007420 247 0.015
positive regulation of gene expression GO:0010628 244 0.015
establishment of protein localization GO:0045184 141 0.015
regulation of anatomical structure size GO:0090066 135 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
ras protein signal transduction GO:0007265 29 0.015
positive regulation of immune response GO:0050778 42 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
regulation of cell adhesion GO:0030155 52 0.015
organic hydroxy compound biosynthetic process GO:1901617 51 0.015
nucleotide metabolic process GO:0009117 279 0.015
response to acid chemical GO:0001101 222 0.015
protein heterooligomerization GO:0051291 89 0.015
response to insulin GO:0032868 133 0.015
regulation of protein kinase activity GO:0045859 105 0.015
erythrocyte homeostasis GO:0034101 2 0.015
regulation of kinase activity GO:0043549 117 0.015
ribonucleoside metabolic process GO:0009119 174 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
purine containing compound catabolic process GO:0072523 138 0.014
purine containing compound metabolic process GO:0072521 253 0.014
response to bacterium GO:0009617 200 0.014
negative regulation of transport GO:0051051 136 0.014
positive regulation of immune system process GO:0002684 90 0.014
insulin receptor signaling pathway GO:0008286 24 0.014
actin filament organization GO:0007015 42 0.014
negative regulation of secretion GO:0051048 82 0.014
regulation of reactive oxygen species metabolic process GO:2000377 26 0.014
circulatory system development GO:0072359 134 0.014
protein autophosphorylation GO:0046777 66 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
response to peptide hormone GO:0043434 278 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
regulation of vesicle mediated transport GO:0060627 81 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
cell cell signaling GO:0007267 335 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
organophosphate catabolic process GO:0046434 148 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
regulation of proteolysis GO:0030162 66 0.013
response to metal ion GO:0010038 253 0.013
b cell differentiation GO:0030183 2 0.013
regulation of t cell proliferation GO:0042129 17 0.013
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
hormone transport GO:0009914 121 0.013
regulation of cellular component size GO:0032535 51 0.013
cellular chemical homeostasis GO:0055082 247 0.013
response to starvation GO:0042594 59 0.013
metal ion homeostasis GO:0055065 186 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
regulation of protein modification process GO:0031399 194 0.013
regulation of nervous system development GO:0051960 264 0.013
macromolecule localization GO:0033036 252 0.013
leukocyte activation GO:0045321 76 0.013
positive regulation of lipid kinase activity GO:0090218 2 0.013
organelle organization GO:0006996 266 0.013
response to molecule of fungal origin GO:0002238 3 0.013
positive regulation of locomotion GO:0040017 102 0.013
regulation of transferase activity GO:0051338 123 0.013
response to toxic substance GO:0009636 133 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
positive regulation of leukocyte proliferation GO:0070665 20 0.013
regulation of cytoskeleton organization GO:0051493 49 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
positive regulation of humoral immune response GO:0002922 2 0.013
growth GO:0040007 165 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
t cell activation GO:0042110 29 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
regulation of lymphocyte proliferation GO:0050670 26 0.013
calcium ion transmembrane transport GO:0070588 70 0.013
platelet aggregation GO:0070527 4 0.013
positive regulation of signal transduction GO:0009967 175 0.013
regulation of vasculature development GO:1901342 44 0.012
cellular response to molecule of fungal origin GO:0071226 1 0.012
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.012
cellular component morphogenesis GO:0032989 155 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 1 0.012
mitotic spindle organization GO:0007052 2 0.012
head development GO:0060322 247 0.012
cellular response to stress GO:0033554 269 0.012
gland development GO:0048732 155 0.012
vasculature development GO:0001944 70 0.012
phosphatidylinositol 3 kinase signaling GO:0014065 14 0.012
membrane organization GO:0061024 94 0.012
regulation of peptidase activity GO:0052547 55 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
response to oxidative stress GO:0006979 186 0.012
developmental growth GO:0048589 100 0.012
positive regulation of gamma delta t cell differentiation GO:0045588 1 0.012
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.012
sequestering of metal ion GO:0051238 9 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
regulation of immune response GO:0050776 55 0.012
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
olfactory learning GO:0008355 1 0.012
regulation of leukocyte proliferation GO:0070663 26 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
regulation of homotypic cell cell adhesion GO:0034110 4 0.012
response to transition metal nanoparticle GO:1990267 122 0.011
multicellular organism growth GO:0035264 1 0.011
positive regulation of kinase activity GO:0033674 77 0.011
positive regulation of isotype switching GO:0045830 1 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
response to decreased oxygen levels GO:0036293 237 0.011
cell substrate adhesion GO:0031589 29 0.011
sexual reproduction GO:0019953 148 0.011
actin filament bundle assembly GO:0051017 19 0.011
regulation of cell development GO:0060284 263 0.011
regulation of actin nucleation GO:0051125 2 0.011
positive regulation of cell motility GO:2000147 97 0.011
response to estrogen GO:0043627 232 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
anterior posterior pattern specification GO:0009952 1 0.011
alcohol metabolic process GO:0006066 77 0.011
chemical homeostasis GO:0048878 292 0.011
glomerular mesangial cell proliferation GO:0072110 4 0.011
single organism cellular localization GO:1902580 102 0.011
tissue regeneration GO:0042246 36 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
cellular response to nutrient levels GO:0031669 60 0.011
cation transport GO:0006812 382 0.011
regulation of ion homeostasis GO:2000021 63 0.011
positive regulation of cell migration GO:0030335 96 0.011
lipid biosynthetic process GO:0008610 128 0.011
cell activation involved in immune response GO:0002263 16 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
calcium ion transport GO:0006816 131 0.011
response to hydrogen peroxide GO:0042542 89 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
axis specification GO:0009798 4 0.010
negative regulation of cell matrix adhesion GO:0001953 3 0.010
cellular response to insulin stimulus GO:0032869 81 0.010
positive regulation of rab gtpase activity GO:0032851 3 0.010
calcium ion homeostasis GO:0055074 162 0.010
locomotion GO:0040011 237 0.010
activation of protein kinase b activity GO:0032148 3 0.010
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.010
regulation of neuron projection development GO:0010975 161 0.010
neuron development GO:0048666 286 0.010

Sash3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org