Rattus norvegicus

34 known processes

Scaf1

SR-related CTD-associated factor 1

(Aliases: Sr-a1)

Scaf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna biosynthetic process GO:2001141 381 0.674
regulation of nucleic acid templated transcription GO:1903506 380 0.540
mitotic spindle organization GO:0007052 2 0.450
transcription dna templated GO:0006351 377 0.438
rna metabolic process GO:0016070 406 0.391
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.331
negative regulation of cellular metabolic process GO:0031324 281 0.318
transcription from rna polymerase ii promoter GO:0006366 252 0.281
rna biosynthetic process GO:0032774 380 0.261
nucleic acid templated transcription GO:0097659 379 0.259
regulation of transcription dna templated GO:0006355 374 0.238
peptide biosynthetic process GO:0043043 3 0.212
negative regulation of metabolic process GO:0009892 331 0.177
positive regulation of rna biosynthetic process GO:1902680 197 0.168
regulation of cellular protein metabolic process GO:0032268 267 0.165
positive regulation of biosynthetic process GO:0009891 319 0.165
regulation of rna metabolic process GO:0051252 391 0.164
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.143
chromosome segregation GO:0007059 2 0.138
regulation of apoptotic process GO:0042981 335 0.137
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.134
regulation of molecular function GO:0065009 398 0.129
spindle organization GO:0007051 2 0.119
cell cell signaling GO:0007267 335 0.106
organelle organization GO:0006996 266 0.106
negative regulation of macromolecule metabolic process GO:0010605 260 0.105
regulation of protein phosphorylation GO:0001932 183 0.104
positive regulation of signaling GO:0023056 270 0.102
protein phosphorylation GO:0006468 345 0.102
regulation of protein metabolic process GO:0051246 289 0.098
innate immune response GO:0045087 35 0.094
programmed cell death GO:0012501 392 0.092
reproductive process GO:0022414 372 0.089
negative regulation of gene expression GO:0010629 199 0.086
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.081
apoptotic process GO:0006915 381 0.080
regulation of cell maturation GO:1903429 3 0.079
cellular component assembly GO:0022607 360 0.078
negative regulation of cell communication GO:0010648 158 0.078
response to metal ion GO:0010038 253 0.075
response to nutrient levels GO:0031667 370 0.075
reproduction GO:0000003 245 0.074
anterior posterior pattern specification GO:0009952 1 0.073
central nervous system development GO:0007417 311 0.072
negative regulation of rna metabolic process GO:0051253 123 0.072
regulation of cell differentiation GO:0045595 320 0.072
immune system process GO:0002376 204 0.069
sensory organ development GO:0007423 74 0.067
proteolysis GO:0006508 175 0.066
multi organism reproductive process GO:0044703 262 0.065
macromolecular complex subunit organization GO:0043933 339 0.065
positive regulation of rna metabolic process GO:0051254 203 0.065
negative regulation of transcription dna templated GO:0045892 116 0.064
positive regulation of transcription dna templated GO:0045893 197 0.063
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.062
positive regulation of nucleic acid templated transcription GO:1903508 197 0.061
neuron differentiation GO:0030182 368 0.059
macromolecular complex assembly GO:0065003 273 0.059
tube formation GO:0035148 3 0.058
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.058
response to hexose GO:0009746 144 0.057
intracellular signal transduction GO:0035556 314 0.056
response to nutrient GO:0007584 248 0.056
brain development GO:0007420 247 0.056
response to peptide GO:1901652 292 0.055
positive regulation of molecular function GO:0044093 230 0.054
positive regulation of signal transduction GO:0009967 175 0.053
regulation of multicellular organismal development GO:2000026 376 0.053
response to inorganic substance GO:0010035 377 0.052
positive regulation of cellular biosynthetic process GO:0031328 295 0.052
regulation of signal transduction GO:0009966 318 0.051
neuron development GO:0048666 286 0.051
regulation of phosphorylation GO:0042325 248 0.050
single organism reproductive process GO:0044702 297 0.050
positive regulation of protein metabolic process GO:0051247 178 0.049
response to wounding GO:0009611 254 0.048
regulation of cell development GO:0060284 263 0.048
protein complex assembly GO:0006461 263 0.048
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.048
head development GO:0060322 247 0.046
positive regulation of protein modification process GO:0031401 142 0.046
positive regulation of protein phosphorylation GO:0001934 135 0.045
cellular response to endogenous stimulus GO:0071495 377 0.044
catabolic process GO:0009056 351 0.044
multicellular organismal reproductive process GO:0048609 233 0.044
regulation of intracellular signal transduction GO:1902531 218 0.044
regulation of system process GO:0044057 208 0.043
neuron projection development GO:0031175 273 0.043
response to other organism GO:0051707 220 0.042
oxoacid metabolic process GO:0043436 290 0.042
localization of cell GO:0051674 202 0.041
cellular response to oxygen containing compound GO:1901701 386 0.041
positive regulation of response to stimulus GO:0048584 285 0.041
morphogenesis of embryonic epithelium GO:0016331 3 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.039
positive regulation of transport GO:0051050 245 0.039
regulation of purine nucleotide metabolic process GO:1900542 115 0.039
signal release GO:0023061 145 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.037
regulation of programmed cell death GO:0043067 341 0.037
developmental process involved in reproduction GO:0003006 159 0.037
multi multicellular organism process GO:0044706 138 0.036
positive regulation of gene expression GO:0010628 244 0.036
single organism organelle organization GO:1902589 180 0.036
neurological system process GO:0050877 219 0.036
negative regulation of response to stimulus GO:0048585 155 0.035
reproductive system development GO:0061458 128 0.035
negative regulation of biosynthetic process GO:0009890 168 0.035
response to estrogen GO:0043627 232 0.034
neuron death GO:0070997 127 0.034
reproductive structure development GO:0048608 128 0.033
positive regulation of cell communication GO:0010647 271 0.033
amine metabolic process GO:0009308 38 0.033
oxidation reduction process GO:0055114 304 0.033
synaptic transmission GO:0007268 235 0.032
organic substance catabolic process GO:1901575 316 0.032
regulation of gene expression epigenetic GO:0040029 10 0.032
positive regulation of phosphorylation GO:0042327 177 0.032
cellular amide metabolic process GO:0043603 44 0.032
regulation of nervous system development GO:0051960 264 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
multicellular organism reproduction GO:0032504 233 0.031
organophosphate metabolic process GO:0019637 370 0.031
regulation of neurogenesis GO:0050767 247 0.030
cellular response to nitrogen compound GO:1901699 210 0.030
negative regulation of cell death GO:0060548 229 0.030
negative regulation of signaling GO:0023057 157 0.030
secretion by cell GO:0032940 248 0.030
positive regulation of cellular component organization GO:0051130 200 0.029
nucleotide metabolic process GO:0009117 279 0.029
single organism biosynthetic process GO:0044711 342 0.029
non canonical wnt signaling pathway GO:0035567 3 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.028
regulation of protein modification process GO:0031399 194 0.028
ribonucleoside catabolic process GO:0042454 126 0.028
sex differentiation GO:0007548 113 0.028
organic acid metabolic process GO:0006082 292 0.027
cell cycle process GO:0022402 57 0.027
cellular amine metabolic process GO:0044106 38 0.027
response to carbohydrate GO:0009743 183 0.027
negative regulation of organ growth GO:0046621 3 0.027
defense response GO:0006952 194 0.027
forebrain development GO:0030900 98 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
development of primary sexual characteristics GO:0045137 107 0.026
chemical homeostasis GO:0048878 292 0.026
immune effector process GO:0002252 53 0.026
cellular component biogenesis GO:0044085 368 0.025
gland development GO:0048732 155 0.025
response to monosaccharide GO:0034284 159 0.025
protein complex biogenesis GO:0070271 263 0.025
behavior GO:0007610 205 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
regulation of hydrolase activity GO:0051336 143 0.025
response to extracellular stimulus GO:0009991 380 0.025
response to peptide hormone GO:0043434 278 0.025
enzyme linked receptor protein signaling pathway GO:0007167 116 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
regulation of synaptic transmission GO:0050804 141 0.024
cellular response to insulin stimulus GO:0032869 81 0.024
cellular catabolic process GO:0044248 295 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
regulation of ion transport GO:0043269 245 0.023
regulation of chromosome segregation GO:0051983 1 0.023
organic hydroxy compound metabolic process GO:1901615 115 0.023
cellular homeostasis GO:0019725 252 0.023
regulation of response to external stimulus GO:0032101 106 0.023
single organism cellular localization GO:1902580 102 0.023
response to ketone GO:1901654 182 0.023
eye morphogenesis GO:0048592 4 0.023
response to cytokine GO:0034097 215 0.023
response to vitamin GO:0033273 131 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
gamete generation GO:0007276 124 0.022
negative regulation of molecular function GO:0044092 133 0.022
jak stat cascade GO:0007259 26 0.022
secretion GO:0046903 307 0.022
response to insulin GO:0032868 133 0.022
protein localization to membrane GO:0072657 36 0.022
homeostatic process GO:0042592 331 0.022
single organism intracellular transport GO:1902582 166 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of protein kinase activity GO:0045859 105 0.021
cellular ketone metabolic process GO:0042180 51 0.021
cellular response to stress GO:0033554 269 0.021
axis specification GO:0009798 4 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
cellular carbohydrate metabolic process GO:0044262 72 0.021
response to estradiol GO:0032355 164 0.021
regulation of hormone levels GO:0010817 187 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
single organism behavior GO:0044708 130 0.020
neural tube formation GO:0001841 1 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
protein localization GO:0008104 191 0.020
response to corticosteroid GO:0031960 235 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
positive regulation of developmental process GO:0051094 283 0.020
cell fate determination GO:0001709 2 0.020
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
regulation of catalytic activity GO:0050790 304 0.019
response to glucose GO:0009749 136 0.019
regulation of peptide secretion GO:0002791 82 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
embryonic pattern specification GO:0009880 1 0.019
divalent inorganic cation transport GO:0072511 134 0.019
sexual reproduction GO:0019953 148 0.019
glutamate receptor signaling pathway GO:0007215 43 0.019
cell cycle GO:0007049 101 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
regulation of immune system process GO:0002682 123 0.019
intracellular transport GO:0046907 185 0.018
cell motility GO:0048870 202 0.018
microtubule cytoskeleton organization GO:0000226 25 0.018
regulation of body fluid levels GO:0050878 90 0.018
regulation of proteasomal protein catabolic process GO:0061136 4 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
positive regulation of catabolic process GO:0009896 78 0.018
immune response GO:0006955 104 0.018
olfactory behavior GO:0042048 2 0.018
formation of primary germ layer GO:0001704 1 0.018
tube development GO:0035295 89 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
rna localization GO:0006403 4 0.017
asymmetric protein localization GO:0008105 2 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
epithelial tube formation GO:0072175 3 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
camp biosynthetic process GO:0006171 47 0.017
peptidyl amino acid modification GO:0018193 126 0.017
regulation of cell cycle GO:0051726 73 0.017
chemosensory behavior GO:0007635 2 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
positive regulation of transferase activity GO:0051347 81 0.017
cell projection organization GO:0030030 302 0.017
membrane organization GO:0061024 94 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
positive regulation of cell maturation GO:1903431 3 0.017
regulation of kinase activity GO:0043549 117 0.017
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
spermatogenesis GO:0007283 99 0.017
nucleotide biosynthetic process GO:0009165 98 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.016
gonad development GO:0008406 104 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
small molecule biosynthetic process GO:0044283 124 0.016
establishment of protein localization GO:0045184 141 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
locomotion GO:0040011 237 0.016
protein oligomerization GO:0051259 191 0.016
negative regulation of catalytic activity GO:0043086 103 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
mesoderm development GO:0007498 2 0.016
generation of precursor metabolites and energy GO:0006091 62 0.016
hormone transport GO:0009914 121 0.016
regulation of secretion GO:0051046 224 0.016
single organism catabolic process GO:0044712 283 0.016
rhythmic process GO:0048511 156 0.016
carbohydrate homeostasis GO:0033500 75 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
choline transport GO:0015871 4 0.016
dna hypermethylation GO:0044026 1 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
hormone secretion GO:0046879 115 0.015
cell type specific apoptotic process GO:0097285 134 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
cellular response to hexose stimulus GO:0071331 65 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
metal ion transport GO:0030001 289 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
carbon catabolite activation of transcription GO:0045991 1 0.015
single organism membrane organization GO:0044802 74 0.015
regulation of blood circulation GO:1903522 110 0.015
myelination GO:0042552 39 0.015
dendrite development GO:0016358 72 0.015
lipid biosynthetic process GO:0008610 128 0.015
dna metabolic process GO:0006259 96 0.014
peptide secretion GO:0002790 86 0.014
chromosome organization GO:0051276 36 0.014
regulation of protein maturation GO:1903317 50 0.014
gastrulation GO:0007369 2 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
t cell selection GO:0045058 1 0.014
neural crest cell differentiation GO:0014033 2 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
regulation of cellular protein catabolic process GO:1903362 7 0.014
regulation of hormone secretion GO:0046883 106 0.014
response to acid chemical GO:0001101 222 0.014
regulation of camp metabolic process GO:0030814 43 0.014
positive regulation of secretion GO:0051047 140 0.014
regulation of transferase activity GO:0051338 123 0.014
hepatocyte growth factor receptor signaling pathway GO:0048012 1 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
sensory perception GO:0007600 101 0.013
regulation of mapk cascade GO:0043408 116 0.013
microtubule based process GO:0007017 36 0.013
regulation of cellular component organization GO:0051128 368 0.013
protein complex subunit organization GO:0071822 302 0.013
positive regulation of cell death GO:0010942 184 0.013
negative regulation of tor signaling GO:0032007 2 0.013
cyclic purine nucleotide metabolic process GO:0052652 62 0.013
cellular chemical homeostasis GO:0055082 247 0.013
intracellular protein transport GO:0006886 79 0.013
negative regulation of developmental process GO:0051093 125 0.013
regulation of insulin secretion GO:0050796 65 0.013
regulation of proteolysis GO:0030162 66 0.013
response to oxidative stress GO:0006979 186 0.013
response to alkaloid GO:0043279 132 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
muscle system process GO:0003012 115 0.013
regulation of protein processing GO:0070613 50 0.013
response to ethanol GO:0045471 162 0.013
female gonad development GO:0008585 53 0.013
male gamete generation GO:0048232 99 0.012
amide transport GO:0042886 105 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
tissue development GO:0009888 252 0.012
dendrite morphogenesis GO:0048813 43 0.012
protein maturation GO:0051604 68 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
circadian rhythm GO:0007623 88 0.012
monocarboxylic acid biosynthetic process GO:0072330 48 0.012
response to external biotic stimulus GO:0043207 221 0.012
adult locomotory behavior GO:0008344 4 0.012
digestive tract development GO:0048565 39 0.012
protein homooligomerization GO:0051260 91 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.012
cation transport GO:0006812 382 0.012
positive regulation of cell development GO:0010720 176 0.012
aromatic compound catabolic process GO:0019439 168 0.012
heart morphogenesis GO:0003007 3 0.012
response to mechanical stimulus GO:0009612 134 0.012
female pregnancy GO:0007565 122 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.012
mitotic sister chromatid segregation GO:0000070 1 0.012
insulin secretion GO:0030073 69 0.012
epithelial cell differentiation GO:0030855 71 0.012
cellular response to peptide GO:1901653 133 0.012
biological adhesion GO:0022610 110 0.012
embryonic epithelial tube formation GO:0001838 3 0.012
cardiac chamber development GO:0003205 1 0.012
action potential GO:0001508 54 0.012
ribose phosphate metabolic process GO:0019693 235 0.011
negative regulation of signal transduction GO:0009968 83 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
negative regulation of transport GO:0051051 136 0.011
regulation of mitochondrion organization GO:0010821 7 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
regulation of embryonic development GO:0045995 2 0.011
positive regulation of organelle organization GO:0010638 48 0.011
neuron apoptotic process GO:0051402 88 0.011
regulation of transmembrane transport GO:0034762 122 0.011
mitotic cell cycle process GO:1903047 35 0.011
hepaticobiliary system development GO:0061008 90 0.011
heart process GO:0003015 57 0.011
macromolecule catabolic process GO:0009057 58 0.011
endoplasmic reticulum organization GO:0007029 1 0.011
receptor metabolic process GO:0043112 18 0.011
peptide transport GO:0015833 97 0.011
female sex differentiation GO:0046660 59 0.011
positive regulation of kinase activity GO:0033674 77 0.011
macromolecule localization GO:0033036 252 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
nitrogen compound transport GO:0071705 229 0.011
peptidyl serine modification GO:0018209 34 0.011
peptidyl serine phosphorylation GO:0018105 33 0.011
pyruvate metabolic process GO:0006090 27 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
positive regulation of mitochondrion organization GO:0010822 4 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.010
lipid metabolic process GO:0006629 283 0.010
embryo development GO:0009790 49 0.010
regulation of cell proliferation GO:0042127 359 0.010
purine nucleotide biosynthetic process GO:0006164 83 0.010
purine containing compound metabolic process GO:0072521 253 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
organic acid transport GO:0015849 116 0.010
response to calcium ion GO:0051592 59 0.010
purine nucleoside monophosphate metabolic process GO:0009126 84 0.010
regulation of protein serine threonine kinase activity GO:0071900 64 0.010
peptide metabolic process GO:0006518 32 0.010
regulation of cellular response to stress GO:0080135 49 0.010
calcium ion transport GO:0006816 131 0.010
development of primary female sexual characteristics GO:0046545 56 0.010
positive regulation of mitochondrial membrane permeability GO:0035794 1 0.010
organic acid biosynthetic process GO:0016053 83 0.010

Scaf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.047
neuropathy DOID:870 0 0.047
neuromuscular disease DOID:440 0 0.047
charcot marie tooth disease type 2 DOID:0050539 0 0.047
disease of anatomical entity DOID:7 0 0.047
charcot marie tooth disease DOID:10595 0 0.047
central nervous system disease DOID:331 0 0.012