Rattus norvegicus

17 known processes

Scn4a

sodium channel, voltage-gated, type IV, alpha subunit

(Aliases: microI,NCHVS,Nav1.4)

Scn4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to corticosteroid GO:0031960 235 0.758
neurological system process GO:0050877 219 0.731
Rat
response to estrogen GO:0043627 232 0.682
regulation of secretion GO:0051046 224 0.664
regulation of cellular localization GO:0060341 263 0.654
cellular response to endogenous stimulus GO:0071495 377 0.613
cation transmembrane transport GO:0098655 263 0.590
Mouse Rat
cellular response to oxygen containing compound GO:1901701 386 0.583
cognition GO:0050890 92 0.581
single organism behavior GO:0044708 130 0.562
cellular response to organonitrogen compound GO:0071417 197 0.562
regulation of phosphorus metabolic process GO:0051174 349 0.537
response to estradiol GO:0032355 164 0.513
sensory perception GO:0007600 101 0.461
Rat
nitrogen compound transport GO:0071705 229 0.441
regulation of transcription dna templated GO:0006355 374 0.428
neuron neuron synaptic transmission GO:0007270 60 0.396
secretion by cell GO:0032940 248 0.386
positive regulation of phosphate metabolic process GO:0045937 262 0.376
response to wounding GO:0009611 254 0.371
regulation of cell proliferation GO:0042127 359 0.356
Rat
synaptic transmission GO:0007268 235 0.348
carbohydrate derivative biosynthetic process GO:1901137 124 0.347
rhythmic process GO:0048511 156 0.345
anion transport GO:0006820 178 0.344
cellular homeostasis GO:0019725 252 0.341
regulation of phosphate metabolic process GO:0019220 349 0.340
regulation of cell development GO:0060284 263 0.332
circadian rhythm GO:0007623 88 0.320
positive regulation of cellular biosynthetic process GO:0031328 295 0.318
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.307
nucleoside phosphate biosynthetic process GO:1901293 102 0.287
cellular chemical homeostasis GO:0055082 247 0.280
positive regulation of phosphorylation GO:0042327 177 0.277
regulation of nucleic acid templated transcription GO:1903506 380 0.277
response to acid chemical GO:0001101 222 0.269
response to extracellular stimulus GO:0009991 380 0.268
positive regulation of biosynthetic process GO:0009891 319 0.268
protein phosphorylation GO:0006468 345 0.267
behavior GO:0007610 205 0.265
cellular response to nitrogen compound GO:1901699 210 0.264
response to glucocorticoid GO:0051384 223 0.263
cellular response to hormone stimulus GO:0032870 247 0.261
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.260
carbohydrate derivative metabolic process GO:1901135 346 0.257
homeostatic process GO:0042592 331 0.254
mapk cascade GO:0000165 140 0.247
transmembrane transport GO:0055085 412 0.246
Mouse Rat
positive regulation of transcription dna templated GO:0045893 197 0.246
regulation of rna biosynthetic process GO:2001141 381 0.239
reproductive process GO:0022414 372 0.236
regulation of signal transduction GO:0009966 318 0.233
metal ion transport GO:0030001 289 0.229
multi organism reproductive process GO:0044703 262 0.228
multi multicellular organism process GO:0044706 138 0.225
negative regulation of metabolic process GO:0009892 331 0.225
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.224
reproduction GO:0000003 245 0.224
regulation of catecholamine secretion GO:0050433 32 0.223
positive regulation of cell proliferation GO:0008284 249 0.222
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.221
response to alkaloid GO:0043279 132 0.220
memory GO:0007613 54 0.219
purine ribonucleotide biosynthetic process GO:0009152 81 0.217
enzyme linked receptor protein signaling pathway GO:0007167 116 0.216
rna metabolic process GO:0016070 406 0.215
potassium ion transport GO:0006813 97 0.214
protein homooligomerization GO:0051260 91 0.213
response to nutrient levels GO:0031667 370 0.212
transcription from rna polymerase ii promoter GO:0006366 252 0.212
regulation of synaptic transmission GO:0050804 141 0.208
response to oxygen levels GO:0070482 265 0.208
multicellular organism reproduction GO:0032504 233 0.207
organonitrogen compound biosynthetic process GO:1901566 167 0.202
positive regulation of signal transduction GO:0009967 175 0.202
chemical homeostasis GO:0048878 292 0.201
hormone transport GO:0009914 121 0.200
organophosphate metabolic process GO:0019637 370 0.199
cardiovascular system development GO:0072358 134 0.198
positive regulation of cell communication GO:0010647 271 0.195
camp metabolic process GO:0046058 63 0.193
regulation of phosphorylation GO:0042325 248 0.192
positive regulation of rna biosynthetic process GO:1902680 197 0.187
cellular component assembly GO:0022607 360 0.187
cellular component biogenesis GO:0044085 368 0.186
purine containing compound metabolic process GO:0072521 253 0.182
catecholamine transport GO:0051937 37 0.182
macromolecular complex subunit organization GO:0043933 339 0.181
positive regulation of gene expression GO:0010628 244 0.181
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.180
regulation of system process GO:0044057 208 0.179
Rat
cellular calcium ion homeostasis GO:0006874 160 0.178
negative regulation of macromolecule metabolic process GO:0010605 260 0.178
response to ethanol GO:0045471 162 0.178
rna biosynthetic process GO:0032774 380 0.177
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.174
neuron differentiation GO:0030182 368 0.171
nucleic acid templated transcription GO:0097659 379 0.169
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.165
cellular response to lipid GO:0071396 201 0.164
positive regulation of phosphorus metabolic process GO:0010562 262 0.163
regulation of peptide transport GO:0090087 87 0.162
response to peptide GO:1901652 292 0.161
calcium ion homeostasis GO:0055074 162 0.159
amine transport GO:0015837 57 0.159
negative regulation of cell proliferation GO:0008285 119 0.159
ion transmembrane transport GO:0034220 365 0.159
Mouse Rat
inorganic cation transmembrane transport GO:0098662 202 0.158
Mouse Rat
cation transport GO:0006812 382 0.158
inorganic ion transmembrane transport GO:0098660 229 0.155
Mouse Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.153
regulation of protein modification process GO:0031399 194 0.151
signal transduction by phosphorylation GO:0023014 144 0.150
regulation of protein phosphorylation GO:0001932 183 0.149
cellular metal ion homeostasis GO:0006875 172 0.148
response to growth factor GO:0070848 189 0.147
protein oligomerization GO:0051259 191 0.143
purine nucleotide biosynthetic process GO:0006164 83 0.142
response to inorganic substance GO:0010035 377 0.141
brain development GO:0007420 247 0.139
Rat
inflammatory response GO:0006954 150 0.138
positive regulation of nervous system development GO:0051962 178 0.137
regulation of secretion by cell GO:1903530 208 0.137
intracellular signal transduction GO:0035556 314 0.135
regulation of intracellular signal transduction GO:1902531 218 0.134
nucleobase containing small molecule metabolic process GO:0055086 316 0.134
organic hydroxy compound transport GO:0015850 77 0.134
positive regulation of developmental process GO:0051094 283 0.132
cytosolic calcium ion homeostasis GO:0051480 140 0.132
protein complex subunit organization GO:0071822 302 0.129
response to carbohydrate GO:0009743 183 0.129
response to hypoxia GO:0001666 231 0.129
regulation of cyclase activity GO:0031279 21 0.129
single organism reproductive process GO:0044702 297 0.128
secretion GO:0046903 307 0.127
aging GO:0007568 241 0.127
positive regulation of protein modification process GO:0031401 142 0.126
response to ammonium ion GO:0060359 71 0.125
purine containing compound biosynthetic process GO:0072522 85 0.124
cyclic nucleotide biosynthetic process GO:0009190 63 0.124
learning or memory GO:0007611 90 0.123
regulation of rna metabolic process GO:0051252 391 0.121
response to radiation GO:0009314 137 0.121
nucleoside phosphate metabolic process GO:0006753 283 0.119
cyclic purine nucleotide metabolic process GO:0052652 62 0.118
cyclic nucleotide metabolic process GO:0009187 80 0.118
catecholamine secretion GO:0050432 33 0.118
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.117
response to cytokine GO:0034097 215 0.115
positive regulation of nucleotide metabolic process GO:0045981 91 0.115
learning GO:0007612 33 0.115
regulation of cellular protein metabolic process GO:0032268 267 0.115
regulation of molecular function GO:0065009 398 0.114
central nervous system development GO:0007417 311 0.113
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.113
monoamine transport GO:0015844 43 0.113
neuron death GO:0070997 127 0.113
ribonucleotide metabolic process GO:0009259 231 0.112
response to peptide hormone GO:0043434 278 0.111
regulation of neurogenesis GO:0050767 247 0.111
negative regulation of cellular metabolic process GO:0031324 281 0.111
regulation of dopamine secretion GO:0014059 15 0.111
positive regulation of mapk cascade GO:0043410 92 0.111
macromolecule localization GO:0033036 252 0.110
multicellular organismal reproductive process GO:0048609 233 0.110
regulation of catalytic activity GO:0050790 304 0.110
neuron apoptotic process GO:0051402 88 0.110
negative regulation of programmed cell death GO:0043069 183 0.108
telencephalon development GO:0021537 62 0.108
Rat
oxoacid metabolic process GO:0043436 290 0.106
regulation of programmed cell death GO:0043067 341 0.106
transcription dna templated GO:0006351 377 0.106
protein complex biogenesis GO:0070271 263 0.105
purine ribonucleotide metabolic process GO:0009150 227 0.104
positive regulation of signaling GO:0023056 270 0.104
oxidation reduction process GO:0055114 304 0.103
apoptotic process GO:0006915 381 0.102
regulation of protein metabolic process GO:0051246 289 0.102
negative regulation of cell death GO:0060548 229 0.101
protein complex assembly GO:0006461 263 0.100
response to decreased oxygen levels GO:0036293 237 0.100
regulation of nucleotide biosynthetic process GO:0030808 47 0.100
cell activation GO:0001775 97 0.098
cellular ion homeostasis GO:0006873 184 0.097
response to retinoic acid GO:0032526 63 0.097
ribose phosphate biosynthetic process GO:0046390 87 0.096
cation homeostasis GO:0055080 195 0.096
negative regulation of gene expression GO:0010629 199 0.096
cellular cation homeostasis GO:0030003 180 0.094
cellular response to stress GO:0033554 269 0.093
cellular divalent inorganic cation homeostasis GO:0072503 162 0.093
response to nutrient GO:0007584 248 0.092
regulation of anatomical structure morphogenesis GO:0022603 141 0.092
positive regulation of response to stimulus GO:0048584 285 0.091
negative regulation of phosphorus metabolic process GO:0010563 80 0.091
regulation of purine nucleotide metabolic process GO:1900542 115 0.090
synapse organization GO:0050808 46 0.089
negative regulation of response to stimulus GO:0048585 155 0.089
neuron development GO:0048666 286 0.088
regulation of ion transport GO:0043269 245 0.088
Mouse Rat
nucleotide biosynthetic process GO:0009165 98 0.088
organelle organization GO:0006996 266 0.088
negative regulation of signaling GO:0023057 157 0.088
positive regulation of ion transport GO:0043270 94 0.087
regulation of cell differentiation GO:0045595 320 0.087
cellular response to glucocorticoid stimulus GO:0071385 68 0.087
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.087
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.086
immune system process GO:0002376 204 0.085
positive regulation of cell development GO:0010720 176 0.085
cell projection organization GO:0030030 302 0.085
carbohydrate homeostasis GO:0033500 75 0.085
regulation of camp metabolic process GO:0030814 43 0.085
positive regulation of protein phosphorylation GO:0001934 135 0.084
regulation of neuron differentiation GO:0045664 208 0.083
organ regeneration GO:0031100 101 0.083
cellular response to organic cyclic compound GO:0071407 202 0.082
ribose phosphate metabolic process GO:0019693 235 0.082
g protein coupled receptor signaling pathway GO:0007186 242 0.081
dopamine transport GO:0015872 18 0.081
regulation of locomotion GO:0040012 148 0.080
nucleotide metabolic process GO:0009117 279 0.080
positive regulation of rna metabolic process GO:0051254 203 0.080
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.079
positive regulation of secretion by cell GO:1903532 128 0.078
organic anion transport GO:0015711 132 0.078
response to light stimulus GO:0009416 52 0.078
regulation of nervous system development GO:0051960 264 0.078
cellular response to growth factor stimulus GO:0071363 162 0.077
positive regulation of cellular component organization GO:0051130 200 0.077
response to calcium ion GO:0051592 59 0.077
regulation of amine transport GO:0051952 54 0.076
organic acid metabolic process GO:0006082 292 0.075
regulation of metal ion transport GO:0010959 118 0.075
macromolecular complex assembly GO:0065003 273 0.074
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.072
positive regulation of cell differentiation GO:0045597 217 0.072
circulatory system development GO:0072359 134 0.072
positive regulation of transport GO:0051050 245 0.070
cell cell signaling GO:0007267 335 0.069
gland development GO:0048732 155 0.069
purine nucleotide metabolic process GO:0006163 229 0.068
neuronal action potential GO:0019228 35 0.068
Rat
positive regulation of long term synaptic potentiation GO:1900273 4 0.068
response to cocaine GO:0042220 39 0.068
signal release GO:0023061 145 0.068
regulation of synaptic plasticity GO:0048167 70 0.066
regulation of potassium ion transport GO:0043266 29 0.065
muscle system process GO:0003012 115 0.065
ion homeostasis GO:0050801 212 0.064
positive regulation of multicellular organismal process GO:0051240 387 0.064
Rat
organophosphate biosynthetic process GO:0090407 143 0.063
positive regulation of catalytic activity GO:0043085 184 0.063
single organism catabolic process GO:0044712 283 0.062
striated muscle contraction GO:0006941 44 0.062
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.062
sexual reproduction GO:0019953 148 0.061
positive regulation of protein metabolic process GO:0051247 178 0.061
regulation of transferase activity GO:0051338 123 0.061
regulation of hormone secretion GO:0046883 106 0.060
protein heterooligomerization GO:0051291 89 0.060
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.059
glucose homeostasis GO:0042593 75 0.059
wound healing GO:0042060 122 0.058
regulation of apoptotic process GO:0042981 335 0.058
ribonucleotide biosynthetic process GO:0009260 85 0.058
response to monosaccharide GO:0034284 159 0.057
response to other organism GO:0051707 220 0.057
negative regulation of phosphate metabolic process GO:0045936 80 0.056
regeneration GO:0031099 163 0.056
heart development GO:0007507 72 0.056
organic hydroxy compound metabolic process GO:1901615 115 0.056
tissue development GO:0009888 252 0.056
negative regulation of nervous system development GO:0051961 79 0.056
response to insulin GO:0032868 133 0.055
regulation of membrane potential GO:0042391 110 0.055
Rat
protein localization GO:0008104 191 0.054
epithelial cell differentiation GO:0030855 71 0.054
dopamine secretion GO:0014046 15 0.054
response to toxic substance GO:0009636 133 0.053
positive regulation of neurogenesis GO:0050769 165 0.053
negative regulation of apoptotic process GO:0043066 181 0.053
response to metal ion GO:0010038 253 0.053
negative regulation of secretion by cell GO:1903531 72 0.053
regulation of growth GO:0040008 105 0.052
response to hexose GO:0009746 144 0.052
amino acid transport GO:0006865 70 0.051
regulation of mapk cascade GO:0043408 116 0.051
anatomical structure morphogenesis GO:0009653 298 0.051
Rat
regulation of nucleotide metabolic process GO:0006140 117 0.051
biological adhesion GO:0022610 110 0.049
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.049
response to oxidative stress GO:0006979 186 0.049
sensory perception of pain GO:0019233 73 0.049
Rat
regulation of peptide secretion GO:0002791 82 0.048
neurotransmitter transport GO:0006836 42 0.048
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.048
positive regulation of neuron projection development GO:0010976 99 0.048
positive regulation of neuron differentiation GO:0045666 126 0.048
calcium ion transport GO:0006816 131 0.047
myelination GO:0042552 39 0.046
Rat
defense response GO:0006952 194 0.046
amine metabolic process GO:0009308 38 0.046
head development GO:0060322 247 0.046
Rat
carboxylic acid transport GO:0046942 115 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.045
organic substance catabolic process GO:1901575 316 0.045
cellular response to cytokine stimulus GO:0071345 127 0.045
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 10 0.045
growth GO:0040007 165 0.045
regulation of multicellular organismal development GO:2000026 376 0.045
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.044
divalent inorganic cation homeostasis GO:0072507 165 0.044
peptide hormone secretion GO:0030072 84 0.044
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.044
action potential GO:0001508 54 0.044
Rat
response to purine containing compound GO:0014074 126 0.044
positive regulation of molecular function GO:0044093 230 0.044
regulation of insulin secretion GO:0050796 65 0.043
camp biosynthetic process GO:0006171 47 0.043
response to ketone GO:1901654 182 0.043
regulation of hormone levels GO:0010817 187 0.043
cellular response to alkaloid GO:0071312 25 0.043
regulation of response to wounding GO:1903034 69 0.042
response to organophosphorus GO:0046683 102 0.042
copulation GO:0007620 17 0.042
establishment of protein localization GO:0045184 141 0.042
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.042
programmed cell death GO:0012501 392 0.041
negative adaptation of signaling pathway GO:0022401 10 0.041
blood vessel development GO:0001568 69 0.041
angiogenesis GO:0001525 53 0.041
ossification GO:0001503 70 0.041
hormone secretion GO:0046879 115 0.040
regulation of organelle organization GO:0033043 80 0.040
regulation of protein kinase activity GO:0045859 105 0.040
cell type specific apoptotic process GO:0097285 134 0.040
regulation of neurotransmitter levels GO:0001505 42 0.040
long term synaptic potentiation GO:0060291 21 0.039
regulation of muscle system process GO:0090257 79 0.039
Rat
choline transport GO:0015871 4 0.039
cellular response to steroid hormone stimulus GO:0071383 93 0.039
negative regulation of camp biosynthetic process GO:0030818 12 0.039
neuron fate commitment GO:0048663 4 0.039
regulation of response to stress GO:0080134 126 0.039
olfactory learning GO:0008355 1 0.038
neuron projection development GO:0031175 273 0.037
cell adhesion GO:0007155 110 0.037
single organism carbohydrate metabolic process GO:0044723 118 0.037
cellular response to alcohol GO:0097306 87 0.037
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.036
cellular amine metabolic process GO:0044106 38 0.036
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.036
divalent metal ion transport GO:0070838 132 0.036
positive regulation of synaptic transmission GO:0050806 62 0.036
response to biotic stimulus GO:0009607 226 0.036
negative regulation of cellular protein metabolic process GO:0032269 106 0.036
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
response to external biotic stimulus GO:0043207 221 0.036
regulation of neuron projection development GO:0010975 161 0.036
negative regulation of cell communication GO:0010648 158 0.036
response to camp GO:0051591 91 0.035
female pregnancy GO:0007565 122 0.035
negative regulation of developmental process GO:0051093 125 0.035
heart contraction GO:0060047 57 0.035
Rat
alcohol metabolic process GO:0006066 77 0.035
leukocyte activation GO:0045321 76 0.035
immunoglobulin mediated immune response GO:0016064 4 0.034
positive regulation of transferase activity GO:0051347 81 0.034
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.034
regulation of heart contraction GO:0008016 48 0.034
Rat
renal system process GO:0003014 40 0.034
regulation of neuron apoptotic process GO:0043523 83 0.034
locomotion GO:0040011 237 0.034
circulatory system process GO:0003013 183 0.034
Rat
single organism biosynthetic process GO:0044711 342 0.034
phototransduction visible light GO:0007603 2 0.033
negative regulation of nucleic acid templated transcription GO:1903507 117 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.033
detection of visible light GO:0009584 3 0.033
eye development GO:0001654 50 0.033
camera type eye development GO:0043010 48 0.033
positive regulation of cellular amine metabolic process GO:0033240 3 0.032
positive regulation of cellular protein metabolic process GO:0032270 167 0.032
neurotransmitter uptake GO:0001504 3 0.032
organic acid transport GO:0015849 116 0.032
regulation of map kinase activity GO:0043405 53 0.032
negative regulation of secretion GO:0051048 82 0.032
single organism organelle organization GO:1902589 180 0.031
synapse assembly GO:0007416 29 0.031
response to bacterium GO:0009617 200 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
regulation of kinase activity GO:0043549 117 0.031
cellular carbohydrate metabolic process GO:0044262 72 0.031
sleep GO:0030431 30 0.031
monocarboxylic acid transport GO:0015718 52 0.031
regulation of neuron death GO:1901214 115 0.031
regulation of behavior GO:0050795 61 0.030
response to amphetamine GO:0001975 25 0.030
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.030
response to transition metal nanoparticle GO:1990267 122 0.030
positive regulation of kinase activity GO:0033674 77 0.030
positive regulation of secretion GO:0051047 140 0.030
cellular response to peptide GO:1901653 133 0.029
sodium ion transmembrane transport GO:0035725 67 0.029
Mouse Rat
inflammatory response to antigenic stimulus GO:0002437 18 0.029
positive regulation of cell projection organization GO:0031346 111 0.029
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 12 0.029
response to mechanical stimulus GO:0009612 134 0.029
synaptic transmission dopaminergic GO:0001963 11 0.029
negative regulation of transcription dna templated GO:0045892 116 0.028
neuromuscular process GO:0050905 2 0.028
multicellular organismal signaling GO:0035637 44 0.028
Rat
negative regulation of cell development GO:0010721 82 0.027
cellular ketone metabolic process GO:0042180 51 0.027
cellular response to ammonium ion GO:0071242 17 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.027
negative regulation of purine nucleotide metabolic process GO:1900543 23 0.027
neuron projection morphogenesis GO:0048812 122 0.027
negative regulation of biosynthetic process GO:0009890 168 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.026
regulation of response to external stimulus GO:0032101 106 0.026
monovalent inorganic cation transport GO:0015672 172 0.026
peptide transport GO:0015833 97 0.026
dna metabolic process GO:0006259 96 0.026
metal ion homeostasis GO:0055065 186 0.026
developmental growth GO:0048589 100 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.026
negative regulation of nucleotide metabolic process GO:0045980 23 0.026
calcium ion transmembrane transport GO:0070588 70 0.026
cellular component morphogenesis GO:0032989 155 0.026
negative regulation of molecular function GO:0044092 133 0.026
amide transport GO:0042886 105 0.026
regulation of peptide hormone secretion GO:0090276 80 0.026
ovulation cycle GO:0042698 67 0.025
response to glucose GO:0009749 136 0.025
muscle contraction GO:0006936 88 0.025
regulation of calcium ion transport GO:0051924 77 0.025
regulation of blood vessel size GO:0050880 89 0.025
positive regulation of intracellular signal transduction GO:1902533 138 0.025
development of primary sexual characteristics GO:0045137 107 0.025
cellular lipid metabolic process GO:0044255 208 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
second messenger mediated signaling GO:0019932 51 0.025
reproductive system development GO:0061458 128 0.025
response to molecule of bacterial origin GO:0002237 194 0.024
positive regulation of dopamine secretion GO:0033603 8 0.024
regulation of cellular component organization GO:0051128 368 0.024
skeletal system development GO:0001501 41 0.024
locomotory exploration behavior GO:0035641 1 0.024
synaptic transmission glutamatergic GO:0035249 33 0.024
negative regulation of cellular component organization GO:0051129 83 0.024
cellular response to peptide hormone stimulus GO:0071375 120 0.024
regulation of lyase activity GO:0051339 22 0.024
cellular response to insulin stimulus GO:0032869 81 0.024
transmission of nerve impulse GO:0019226 42 0.024
Rat
nerve development GO:0021675 11 0.024
ensheathment of neurons GO:0007272 40 0.023
Rat
negative regulation of defecation GO:2000293 1 0.023
male gamete generation GO:0048232 99 0.023
negative regulation of neuron differentiation GO:0045665 62 0.023
response to histamine GO:0034776 3 0.023
regulation of camp biosynthetic process GO:0030817 38 0.023
synaptic growth at neuromuscular junction GO:0051124 1 0.023
divalent inorganic cation transport GO:0072511 134 0.023
regulation of blood circulation GO:1903522 110 0.023
Rat
synaptic transmission gabaergic GO:0051932 22 0.023
response to reactive oxygen species GO:0000302 120 0.022
cellular response to retinoic acid GO:0071300 27 0.022
forebrain development GO:0030900 98 0.022
Rat
cellular response to corticosteroid stimulus GO:0071384 69 0.022
acid secretion GO:0046717 48 0.022
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.022
regulation of reactive oxygen species metabolic process GO:2000377 26 0.022
catecholamine metabolic process GO:0006584 19 0.022
positive regulation of epithelial cell proliferation GO:0050679 32 0.022
Rat
spermatogenesis GO:0007283 99 0.022
protein transport GO:0015031 132 0.022
cellular response to glucose stimulus GO:0071333 65 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
negative regulation of cyclic nucleotide metabolic process GO:0030800 15 0.021
sensory organ development GO:0007423 74 0.021
negative regulation of camp metabolic process GO:0030815 14 0.021
positive regulation of growth GO:0045927 55 0.021
organ morphogenesis GO:0009887 75 0.021
Rat
immune response GO:0006955 104 0.020
negative regulation of protein phosphorylation GO:0001933 44 0.020
membrane depolarization GO:0051899 32 0.020
embryonic pattern specification GO:0009880 1 0.020
regulation of postsynaptic membrane potential GO:0060078 25 0.020
multicellular organismal movement GO:0050879 17 0.020

Scn4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.059
disease of anatomical entity DOID:7 0 0.059
Human
eye and adnexa disease DOID:1492 0 0.059
nervous system disease DOID:863 0 0.059
eye disease DOID:5614 0 0.059
urinary system disease DOID:18 0 0.026