Rattus norvegicus

81 known processes

Scn5a

sodium channel, voltage-gated, type V, alpha subunit

(Aliases: SCAL)

Scn5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cardiac muscle contraction GO:0055117 17 0.856
Human Mouse
transmembrane transport GO:0055085 412 0.746
inorganic ion transmembrane transport GO:0098660 229 0.620
striated muscle contraction GO:0006941 44 0.559
Human Mouse
cardiac muscle cell contraction GO:0086003 10 0.528
Human Mouse
cardiac muscle contraction GO:0060048 27 0.502
Human Mouse
monovalent inorganic cation transport GO:0015672 172 0.362
macromolecular complex assembly GO:0065003 273 0.272
metal ion homeostasis GO:0055065 186 0.268
cellular divalent inorganic cation homeostasis GO:0072503 162 0.261
cellular response to endogenous stimulus GO:0071495 377 0.257
protein complex assembly GO:0006461 263 0.239
regulation of metal ion transport GO:0010959 118 0.239
Human
actin mediated cell contraction GO:0070252 12 0.237
Human Mouse
circulatory system process GO:0003013 183 0.225
cellular metal ion homeostasis GO:0006875 172 0.216
regulation of ion transport GO:0043269 245 0.215
Human Mouse Rat
cation transmembrane transport GO:0098655 263 0.209
potassium ion transport GO:0006813 97 0.208
Rat
metal ion transport GO:0030001 289 0.204
programmed cell death GO:0012501 392 0.203
cardiac chamber development GO:0003205 1 0.202
Mouse
protein complex biogenesis GO:0070271 263 0.200
apoptotic process GO:0006915 381 0.200
regulation of apoptotic process GO:0042981 335 0.188
cellular component movement GO:0006928 248 0.185
Human Mouse
cell communication involved in cardiac conduction GO:0086065 2 0.184
Human Mouse
ion transmembrane transport GO:0034220 365 0.182
cellular component biogenesis GO:0044085 368 0.177
protein complex subunit organization GO:0071822 302 0.176
cation transport GO:0006812 382 0.176
cellular calcium ion homeostasis GO:0006874 160 0.174
negative regulation of cellular metabolic process GO:0031324 281 0.165
regulation of blood circulation GO:1903522 110 0.163
cellular chemical homeostasis GO:0055082 247 0.161
heart development GO:0007507 72 0.158
Mouse
cardiovascular system development GO:0072358 134 0.157
Mouse
cardiac ventricle development GO:0003231 1 0.152
Mouse
aging GO:0007568 241 0.151
cellular ion homeostasis GO:0006873 184 0.150
organophosphate metabolic process GO:0019637 370 0.145
regulation of secretion GO:0051046 224 0.144
heart process GO:0003015 57 0.143
regulation of system process GO:0044057 208 0.142
muscle system process GO:0003012 115 0.139
Human Mouse
regulation of heart contraction GO:0008016 48 0.137
regulation of membrane potential GO:0042391 110 0.134
forebrain development GO:0030900 98 0.131
regulation of cardiac muscle cell contraction GO:0086004 11 0.122
Human Mouse
heart contraction GO:0060047 57 0.121
cellular component assembly GO:0022607 360 0.121
nucleotide metabolic process GO:0009117 279 0.120
sodium ion transmembrane transport GO:0035725 67 0.118
blood circulation GO:0008015 183 0.116
cytosolic calcium ion homeostasis GO:0051480 140 0.114
multicellular organismal movement GO:0050879 17 0.114
organic hydroxy compound transport GO:0015850 77 0.113
Rat
response to hypoxia GO:0001666 231 0.110
regulation of muscle system process GO:0090257 79 0.109
regulation of rna metabolic process GO:0051252 391 0.106
regulation of cellular localization GO:0060341 263 0.102
cell cell signaling GO:0007267 335 0.100
Mouse
negative regulation of cell proliferation GO:0008285 119 0.099
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.099
muscle tissue development GO:0060537 58 0.097
circulatory system development GO:0072359 134 0.097
Mouse
membrane hyperpolarization GO:0060081 11 0.096
regulation of actin filament based movement GO:1903115 12 0.096
Human Mouse
heart morphogenesis GO:0003007 3 0.091
nitrogen compound transport GO:0071705 229 0.090
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.089
inorganic cation transmembrane transport GO:0098662 202 0.088
response to camp GO:0051591 91 0.087
macromolecular complex subunit organization GO:0043933 339 0.087
muscle structure development GO:0061061 87 0.086
regulation of striated muscle contraction GO:0006942 21 0.085
Human Mouse
cellular cation homeostasis GO:0030003 180 0.084
neurological system process GO:0050877 219 0.084
Rat
cellular homeostasis GO:0019725 252 0.083
fat cell proliferation GO:0070341 2 0.083
regulation of muscle contraction GO:0006937 53 0.082
Human Mouse
gland development GO:0048732 155 0.082
regulation of multicellular organismal development GO:2000026 376 0.081
transcription dna templated GO:0006351 377 0.080
tissue development GO:0009888 252 0.080
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.080
muscle contraction GO:0006936 88 0.079
Human Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.079
regulation of hydrolase activity GO:0051336 143 0.078
nucleobase containing small molecule metabolic process GO:0055086 316 0.078
anatomical structure morphogenesis GO:0009653 298 0.077
membrane repolarization GO:0086009 1 0.077
Human
rna biosynthetic process GO:0032774 380 0.076
regulation of rna biosynthetic process GO:2001141 381 0.076
response to carbohydrate GO:0009743 183 0.074
membrane organization GO:0061024 94 0.074
actin filament based movement GO:0030048 16 0.074
Human Mouse
regulation of transcription dna templated GO:0006355 374 0.074
organic anion transport GO:0015711 132 0.074
regulation of nucleic acid templated transcription GO:1903506 380 0.073
secretion by cell GO:0032940 248 0.073
mrna transcription GO:0009299 2 0.073
developmental growth GO:0048589 100 0.072
response to extracellular stimulus GO:0009991 380 0.072
response to metal ion GO:0010038 253 0.070
Human
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.070
transcription from rna polymerase ii promoter GO:0006366 252 0.070
lipid metabolic process GO:0006629 283 0.068
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.068
response to ethanol GO:0045471 162 0.068
regulation of catalytic activity GO:0050790 304 0.068
monoamine transport GO:0015844 43 0.068
protein homooligomerization GO:0051260 91 0.067
response to peptide hormone GO:0043434 278 0.067
response to external biotic stimulus GO:0043207 221 0.067
response to corticosteroid GO:0031960 235 0.065
negative regulation of cellular biosynthetic process GO:0031327 161 0.064
carboxylic acid metabolic process GO:0019752 289 0.064
locomotion GO:0040011 237 0.064
positive regulation of developmental process GO:0051094 283 0.062
cellular response to nitrogen compound GO:1901699 210 0.062
enzyme linked receptor protein signaling pathway GO:0007167 116 0.061
learning or memory GO:0007611 90 0.060
multi organism reproductive process GO:0044703 262 0.060
thyroid gland development GO:0030878 1 0.060
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.060
cardiac muscle tissue growth GO:0055017 20 0.060
response to ketone GO:1901654 182 0.058
organonitrogen compound catabolic process GO:1901565 179 0.058
monocarboxylic acid metabolic process GO:0032787 152 0.058
cellular response to hormone stimulus GO:0032870 247 0.058
defense response GO:0006952 194 0.057
response to molecule of bacterial origin GO:0002237 194 0.057
regulation of molecular function GO:0065009 398 0.057
neuron differentiation GO:0030182 368 0.056
single organism catabolic process GO:0044712 283 0.056
regulation of cell proliferation GO:0042127 359 0.056
purine nucleoside triphosphate catabolic process GO:0009146 122 0.055
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.055
ribose phosphate metabolic process GO:0019693 235 0.054
ribonucleoside metabolic process GO:0009119 174 0.054
regulation of blood vessel size GO:0050880 89 0.054
oxoacid metabolic process GO:0043436 290 0.054
growth GO:0040007 165 0.054
organ growth GO:0035265 24 0.053
n methyl d aspartate receptor clustering GO:0097114 2 0.053
response to insulin GO:0032868 133 0.053
divalent inorganic cation transport GO:0072511 134 0.052
single organism reproductive process GO:0044702 297 0.052
response to cytokine GO:0034097 215 0.052
regulation of synaptic transmission GO:0050804 141 0.052
musculoskeletal movement GO:0050881 17 0.051
divalent metal ion transport GO:0070838 132 0.051
response to glucocorticoid GO:0051384 223 0.051
response to nutrient GO:0007584 248 0.051
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.051
secretion GO:0046903 307 0.051
single organism behavior GO:0044708 130 0.050
nucleic acid templated transcription GO:0097659 379 0.050
g protein coupled receptor signaling pathway GO:0007186 242 0.050
response to peptide GO:1901652 292 0.050
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.049
hormone secretion GO:0046879 115 0.049
appendage morphogenesis GO:0035107 4 0.049
calcium ion homeostasis GO:0055074 162 0.048
heart growth GO:0060419 20 0.048
single organism organelle organization GO:1902589 180 0.048
cation homeostasis GO:0055080 195 0.048
vitamin d receptor signaling pathway GO:0070561 1 0.047
blood vessel development GO:0001568 69 0.047
blood vessel morphogenesis GO:0048514 58 0.047
response to testosterone GO:0033574 55 0.046
multi multicellular organism process GO:0044706 138 0.046
cardiac muscle tissue development GO:0048738 26 0.046
ion homeostasis GO:0050801 212 0.046
Human
cardiac conduction GO:0061337 2 0.046
Human Mouse
carbohydrate derivative metabolic process GO:1901135 346 0.046
synaptic transmission GO:0007268 235 0.046
organelle organization GO:0006996 266 0.044
catabolic process GO:0009056 351 0.044
reproduction GO:0000003 245 0.044
circadian rhythm GO:0007623 88 0.044
response to nicotine GO:0035094 51 0.043
multicellular organism reproduction GO:0032504 233 0.043
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
purine containing compound metabolic process GO:0072521 253 0.043
glycosyl compound catabolic process GO:1901658 126 0.043
striated muscle tissue development GO:0014706 58 0.042
regulation of lipid biosynthetic process GO:0046890 38 0.042
calcium ion transport GO:0006816 131 0.042
response to other organism GO:0051707 220 0.042
organic acid metabolic process GO:0006082 292 0.042
regulation of potassium ion transport GO:0043266 29 0.041
response to hexose GO:0009746 144 0.041
protein oligomerization GO:0051259 191 0.041
vascular process in circulatory system GO:0003018 96 0.041
rna metabolic process GO:0016070 406 0.041
regulation of membrane repolarization GO:0060306 1 0.041
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.041
response to estrogen GO:0043627 232 0.041
response to organophosphorus GO:0046683 102 0.041
localization of cell GO:0051674 202 0.040
neuron projection morphogenesis GO:0048812 122 0.040
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.040
cardiac muscle cell development GO:0055013 16 0.039
response to estradiol GO:0032355 164 0.039
regulation of hormone levels GO:0010817 187 0.039
positive regulation of transcription dna templated GO:0045893 197 0.039
sleep GO:0030431 30 0.039
rhythmic process GO:0048511 156 0.038
purine nucleotide biosynthetic process GO:0006164 83 0.038
camp metabolic process GO:0046058 63 0.038
glycosyl compound metabolic process GO:1901657 182 0.038
regulation of inhibitory postsynaptic membrane potential GO:0060080 6 0.038
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.038
organophosphate catabolic process GO:0046434 148 0.037
purine ribonucleotide metabolic process GO:0009150 227 0.037
cardiocyte differentiation GO:0035051 22 0.037
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.037
positive regulation of long term synaptic potentiation GO:1900273 4 0.037
negative regulation of multicellular organismal process GO:0051241 203 0.037
negative regulation of molecular function GO:0044092 133 0.037
muscle organ development GO:0007517 50 0.037
regulation of cell differentiation GO:0045595 320 0.036
macromolecule localization GO:0033036 252 0.036
negative regulation of biosynthetic process GO:0009890 168 0.036
vesicle mediated transport GO:0016192 181 0.036
purine nucleotide metabolic process GO:0006163 229 0.036
homeostatic process GO:0042592 331 0.036
Human
negative regulation of developmental process GO:0051093 125 0.036
heterocycle catabolic process GO:0046700 167 0.035
purine containing compound catabolic process GO:0072523 138 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
ribose phosphate biosynthetic process GO:0046390 87 0.035
chemical homeostasis GO:0048878 292 0.034
Human
response to mechanical stimulus GO:0009612 134 0.034
regulation of nucleotide metabolic process GO:0006140 117 0.034
response to purine containing compound GO:0014074 126 0.034
multicellular organismal signaling GO:0035637 44 0.034
Human Mouse Rat
epithelium development GO:0060429 96 0.033
vasculature development GO:0001944 70 0.033
immunoglobulin mediated immune response GO:0016064 4 0.033
regeneration GO:0031099 163 0.033
nucleotide biosynthetic process GO:0009165 98 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
response to decreased oxygen levels GO:0036293 237 0.032
cellular response to growth factor stimulus GO:0071363 162 0.032
response to radiation GO:0009314 137 0.032
vitamin a metabolic process GO:0006776 2 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
bmp signaling pathway GO:0030509 4 0.032
cellular response to organonitrogen compound GO:0071417 197 0.032
ribonucleotide catabolic process GO:0009261 136 0.032
respiratory gaseous exchange GO:0007585 4 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
positive regulation of hydrolase activity GO:0051345 86 0.032
positive regulation of apoptotic process GO:0043065 154 0.032
signal release GO:0023061 145 0.031
regulation of blood pressure GO:0008217 83 0.031
regulation of purine nucleotide metabolic process GO:1900542 115 0.031
regulation of neurogenesis GO:0050767 247 0.031
organic cyclic compound catabolic process GO:1901361 175 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.031
regulation of phagocytosis engulfment GO:0060099 4 0.031
serotonin receptor signaling pathway GO:0007210 10 0.031
purine containing compound biosynthetic process GO:0072522 85 0.030
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.030
actin filament based process GO:0030029 86 0.030
Human Mouse
positive regulation of transport GO:0051050 245 0.030
Human
negative regulation of metabolic process GO:0009892 331 0.030
head development GO:0060322 247 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
regulation of ion transmembrane transporter activity GO:0032412 48 0.030
single organism biosynthetic process GO:0044711 342 0.029
muscle cell proliferation GO:0033002 84 0.029
regulation of catabolic process GO:0009894 113 0.029
cellular response to insulin stimulus GO:0032869 81 0.029
response to toxic substance GO:0009636 133 0.028
aromatic compound catabolic process GO:0019439 168 0.028
tonic smooth muscle contraction GO:0014820 4 0.028
catecholamine transport GO:0051937 37 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.028
feeding behavior GO:0007631 53 0.028
positive regulation of molecular function GO:0044093 230 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.028
behavioral response to nicotine GO:0035095 2 0.028
response to alkaloid GO:0043279 132 0.027
cell projection morphogenesis GO:0048858 123 0.027
positive regulation of nucleotide catabolic process GO:0030813 53 0.027
positive regulation of epithelial cell differentiation GO:0030858 6 0.027
purine ribonucleotide biosynthetic process GO:0009152 81 0.027
cardiac cell development GO:0055006 16 0.027
negative regulation of synaptic transmission glutamatergic GO:0051967 8 0.027
autonomic nervous system development GO:0048483 3 0.027
developmental process involved in reproduction GO:0003006 159 0.027
multicellular organismal reproductive process GO:0048609 233 0.027
cellular response to peptide hormone stimulus GO:0071375 120 0.027
neuron projection development GO:0031175 273 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
negative regulation of signaling GO:0023057 157 0.026
single organism cell adhesion GO:0098602 46 0.026
carbohydrate derivative catabolic process GO:1901136 147 0.026
regulation of transporter activity GO:0032409 50 0.026
regulation of ion transmembrane transport GO:0034765 121 0.026
Human Mouse Rat
cyclic purine nucleotide metabolic process GO:0052652 62 0.026
neural crest cell development GO:0014032 2 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
regulation of transmembrane transporter activity GO:0022898 49 0.025
single organism membrane organization GO:0044802 74 0.025
neuroblast differentiation GO:0014016 1 0.025
gonad development GO:0008406 104 0.025
female gonad development GO:0008585 53 0.025
nucleotide catabolic process GO:0009166 139 0.025
reproductive process GO:0022414 372 0.024
neural crest cell differentiation GO:0014033 2 0.024
positive regulation of secretion GO:0051047 140 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.024
response to glucose GO:0009749 136 0.024
central nervous system development GO:0007417 311 0.024
brain development GO:0007420 247 0.024
ribonucleoside catabolic process GO:0042454 126 0.024
response to monosaccharide GO:0034284 159 0.024
regulation of cation channel activity GO:2001257 23 0.024
motor neuron axon guidance GO:0008045 1 0.023
anion transport GO:0006820 178 0.023
telencephalon development GO:0021537 62 0.023
organ morphogenesis GO:0009887 75 0.023
respiratory system process GO:0003016 3 0.023
hormone transport GO:0009914 121 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
neural crest cell migration GO:0001755 1 0.023
antibiotic transport GO:0042891 2 0.023
response to oxygen levels GO:0070482 265 0.023
regulation of secretion by cell GO:1903530 208 0.023
positive regulation of gene expression GO:0010628 244 0.023
reactive nitrogen species metabolic process GO:2001057 1 0.023
female pregnancy GO:0007565 122 0.022
response to vitamin a GO:0033189 36 0.022
response to transition metal nanoparticle GO:1990267 122 0.022
regulation of catecholamine secretion GO:0050433 32 0.022
regulation of cellular component movement GO:0051270 150 0.022
Human Mouse
intracellular transport GO:0046907 185 0.022
vasodilation GO:0042311 44 0.022
adrenergic receptor signaling pathway GO:0071875 9 0.022
interleukin 18 production GO:0032621 1 0.022
response to ammonium ion GO:0060359 71 0.022
second messenger mediated signaling GO:0019932 51 0.022
regulation of calcium ion transport GO:0051924 77 0.022
l glutamate import GO:0051938 2 0.022
sympathetic nervous system development GO:0048485 1 0.022
catecholamine secretion GO:0050432 33 0.021
muscle cell differentiation GO:0042692 52 0.021
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.021
reproductive system development GO:0061458 128 0.021
cytoskeleton organization GO:0007010 111 0.021
positive regulation of nucleotide metabolic process GO:0045981 91 0.021
purine nucleoside metabolic process GO:0042278 169 0.021
negative regulation of response to external stimulus GO:0032102 37 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.021
positive regulation of camp metabolic process GO:0030816 31 0.021
cellular ketone metabolic process GO:0042180 51 0.021
specification of organ identity GO:0010092 2 0.021
response to hydrogen peroxide GO:0042542 89 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cellular response to mechanical stimulus GO:0071260 48 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
nucleoside metabolic process GO:0009116 179 0.021
sex differentiation GO:0007548 113 0.021
anatomical structure formation involved in morphogenesis GO:0048646 83 0.021
response to inorganic substance GO:0010035 377 0.021
Human
pyruvate metabolic process GO:0006090 27 0.021
spermatogenesis GO:0007283 99 0.020
purine nucleoside catabolic process GO:0006152 124 0.020
carboxylic acid transport GO:0046942 115 0.020
neurotransmitter gated ion channel clustering GO:0072578 3 0.020
nucleoside phosphate biosynthetic process GO:1901293 102 0.020
forebrain generation of neurons GO:0021872 8 0.020
cellular lipid metabolic process GO:0044255 208 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
response to amino acid GO:0043200 75 0.020
response to fatty acid GO:0070542 65 0.020
negative regulation of rna metabolic process GO:0051253 123 0.019
cell cycle checkpoint GO:0000075 2 0.019
regulation of lipid metabolic process GO:0019216 68 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
response to growth factor GO:0070848 189 0.019
regulation of glucose transport GO:0010827 18 0.019
regulation of programmed cell death GO:0043067 341 0.018
single organism intracellular transport GO:1902582 166 0.018
intestinal absorption GO:0050892 3 0.018
response to activity GO:0014823 73 0.018
muscle organ morphogenesis GO:0048644 1 0.018
response to interleukin 1 GO:0070555 55 0.018
synapse organization GO:0050808 46 0.018
artery smooth muscle contraction GO:0014824 4 0.018
single organismal cell cell adhesion GO:0016337 42 0.018
cellular response to prostaglandin stimulus GO:0071379 7 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
positive regulation of vasodilation GO:0045909 29 0.018
oxidation reduction process GO:0055114 304 0.018
immune system process GO:0002376 204 0.018
positive regulation of blood circulation GO:1903524 65 0.018
regulation of sodium ion transport GO:0002028 21 0.018
Human
cellular response to external stimulus GO:0071496 118 0.018
glucan metabolic process GO:0044042 23 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
reproductive structure development GO:0048608 128 0.017
negative regulation of cell communication GO:0010648 158 0.017
neuromuscular process GO:0050905 2 0.017
positive regulation of cellular catabolic process GO:0031331 71 0.017
regulation of tube size GO:0035150 89 0.017
locomotory exploration behavior GO:0035641 1 0.017
cytoplasmic transport GO:0016482 115 0.017
positive regulation of catabolic process GO:0009896 78 0.017
positive regulation of cell death GO:0010942 184 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
cellular response to peptide GO:1901653 133 0.017
locomotory behavior GO:0007626 15 0.017
response to calcium ion GO:0051592 59 0.017
Human
negative regulation of transport GO:0051051 136 0.016
regulation of nucleotide biosynthetic process GO:0030808 47 0.016
regulation of nervous system development GO:0051960 264 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.016
response to mineralocorticoid GO:0051385 49 0.016
intracellular signal transduction GO:0035556 314 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
regulation of fat cell proliferation GO:0070344 1 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
negative regulation of organ growth GO:0046621 3 0.016
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.016
g protein coupled purinergic receptor signaling pathway GO:0035588 8 0.016
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.016
response to uv c GO:0010225 2 0.016
cellular catabolic process GO:0044248 295 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.015
response to lipopolysaccharide GO:0032496 191 0.015
sexual reproduction GO:0019953 148 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
development of primary female sexual characteristics GO:0046545 56 0.015
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.015
regulation of peptide secretion GO:0002791 82 0.015
behavior GO:0007610 205 0.015
purine nucleoside monophosphate metabolic process GO:0009126 84 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
ras protein signal transduction GO:0007265 29 0.015
ribonucleotide biosynthetic process GO:0009260 85 0.015
response to biotic stimulus GO:0009607 226 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
axis specification GO:0009798 4 0.015
negative regulation of transporter activity GO:0032410 13 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
calcium ion transmembrane transport GO:0070588 70 0.015
organic substance catabolic process GO:1901575 316 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
regulation of neuron apoptotic process GO:0043523 83 0.015
regulation of cardiac muscle tissue growth GO:0055021 12 0.014
regulation of neuron differentiation GO:0045664 208 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
regulation of signal transduction GO:0009966 318 0.014
dendrite morphogenesis GO:0048813 43 0.014
protein heterooligomerization GO:0051291 89 0.014
pancreatic stellate cell proliferation GO:0072343 2 0.014
positive regulation of gtpase activity GO:0043547 47 0.014
immune response GO:0006955 104 0.014
regulation of b cell mediated immunity GO:0002712 2 0.014
protein phosphorylation GO:0006468 345 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
g protein coupled receptor internalization GO:0002031 3 0.014
proteolysis GO:0006508 175 0.014
cellular response to stress GO:0033554 269 0.014
positive regulation of interleukin 18 production GO:0032741 1 0.014
cellular protein complex assembly GO:0043623 44 0.014
response to reactive oxygen species GO:0000302 120 0.014
cellular response to acid chemical GO:0071229 75 0.014
inflammatory response GO:0006954 150 0.014

Scn5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
Human
cardiovascular system disease DOID:1287 0 0.051
Human
long qt syndrome DOID:2843 0 0.050
Human
nervous system disease DOID:863 0 0.044
central nervous system disease DOID:331 0 0.038
kidney disease DOID:557 0 0.033
urinary system disease DOID:18 0 0.033
heart disease DOID:114 0 0.030
Human
congenital heart disease DOID:1682 0 0.030
heart septal defect DOID:1681 0 0.030
atrial heart septal defect DOID:1882 0 0.030
heart conduction disease DOID:10273 0 0.022
Human
brain disease DOID:936 0 0.021