Rattus norvegicus

0 known processes

Sdk2

sidekick homolog 2 (chicken)

Sdk2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nervous system development GO:0051960 264 0.174
receptor localization to synapse GO:0097120 2 0.173
neuron development GO:0048666 286 0.144
neuron projection development GO:0031175 273 0.143
cell projection organization GO:0030030 302 0.141
neuron differentiation GO:0030182 368 0.132
anatomical structure morphogenesis GO:0009653 298 0.130
glutamate receptor signaling pathway GO:0007215 43 0.126
regulation of signal transduction GO:0009966 318 0.122
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.121
anterior posterior pattern specification GO:0009952 1 0.111
synaptic growth at neuromuscular junction GO:0051124 1 0.110
cellular component assembly GO:0022607 360 0.105
synaptic transmission GO:0007268 235 0.105
regulation of multicellular organismal development GO:2000026 376 0.099
regulation of cellular component organization GO:0051128 368 0.095
protein complex subunit organization GO:0071822 302 0.095
cell cell signaling GO:0007267 335 0.091
ion transmembrane transport GO:0034220 365 0.087
positive regulation of transport GO:0051050 245 0.086
cell morphogenesis involved in differentiation GO:0000904 119 0.085
regulation of neuron differentiation GO:0045664 208 0.084
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.083
protein complex biogenesis GO:0070271 263 0.083
regulation of glutamate receptor signaling pathway GO:1900449 17 0.079
regulation of rna metabolic process GO:0051252 391 0.079
rna metabolic process GO:0016070 406 0.077
regulation of ion transmembrane transport GO:0034765 121 0.076
locomotion GO:0040011 237 0.076
positive regulation of signaling GO:0023056 270 0.075
regulation of cell differentiation GO:0045595 320 0.074
regulation of neuron projection development GO:0010975 161 0.074
regulation of molecular function GO:0065009 398 0.072
regulation of secretion GO:0051046 224 0.070
positive regulation of developmental process GO:0051094 283 0.070
transcription dna templated GO:0006351 377 0.070
negative regulation of receptor internalization GO:0002091 2 0.068
regulation of synaptic transmission GO:0050804 141 0.068
regulation of transcription dna templated GO:0006355 374 0.068
regulation of nucleic acid templated transcription GO:1903506 380 0.065
secretion by cell GO:0032940 248 0.065
regulation of neurogenesis GO:0050767 247 0.065
regulation of transmembrane transport GO:0034762 122 0.065
regulation of phosphate metabolic process GO:0019220 349 0.065
synapse assembly GO:0007416 29 0.064
nucleic acid templated transcription GO:0097659 379 0.064
cellular component biogenesis GO:0044085 368 0.062
positive regulation of neuron projection development GO:0010976 99 0.062
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.061
negative regulation of rna metabolic process GO:0051253 123 0.060
rna biosynthetic process GO:0032774 380 0.059
positive regulation of multicellular organismal process GO:0051240 387 0.056
regulation of cell projection organization GO:0031344 175 0.055
regulation of protein localization GO:0032880 81 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.055
cellular component morphogenesis GO:0032989 155 0.053
cell part morphogenesis GO:0032990 123 0.053
cellular amino acid metabolic process GO:0006520 107 0.053
axis specification GO:0009798 4 0.053
embryonic axis specification GO:0000578 1 0.052
dendrite development GO:0016358 72 0.051
macromolecule localization GO:0033036 252 0.051
regulation of secretion by cell GO:1903530 208 0.050
organelle organization GO:0006996 266 0.049
behavior GO:0007610 205 0.049
negative regulation of metabolic process GO:0009892 331 0.048
axon development GO:0061564 96 0.048
positive regulation of secretion GO:0051047 140 0.048
positive regulation of nervous system development GO:0051962 178 0.048
regulation of receptor activity GO:0010469 29 0.047
dendritic spine morphogenesis GO:0060997 9 0.047
regulation of cell development GO:0060284 263 0.047
positive regulation of neurogenesis GO:0050769 165 0.047
regulation of rna biosynthetic process GO:2001141 381 0.046
protein localization GO:0008104 191 0.046
negative regulation of nucleic acid templated transcription GO:1903507 117 0.046
axonogenesis GO:0007409 71 0.045
central nervous system development GO:0007417 311 0.045
dendrite morphogenesis GO:0048813 43 0.044
cation homeostasis GO:0055080 195 0.044
cell cycle GO:0007049 101 0.044
cytoskeleton organization GO:0007010 111 0.043
cellular component movement GO:0006928 248 0.043
cellular response to stress GO:0033554 269 0.042
positive regulation of cellular component organization GO:0051130 200 0.041
negative regulation of gene expression GO:0010629 199 0.041
brain development GO:0007420 247 0.041
metal ion homeostasis GO:0055065 186 0.041
regulation of phosphorus metabolic process GO:0051174 349 0.041
regulation of catalytic activity GO:0050790 304 0.041
embryonic pattern specification GO:0009880 1 0.041
regulation of intracellular signal transduction GO:1902531 218 0.040
single organism behavior GO:0044708 130 0.040
positive regulation of membrane potential GO:0045838 16 0.040
macromolecular complex assembly GO:0065003 273 0.040
negative regulation of cellular metabolic process GO:0031324 281 0.040
intracellular signal transduction GO:0035556 314 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.038
regulation of cellular localization GO:0060341 263 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.038
transmembrane transport GO:0055085 412 0.038
neurological system process GO:0050877 219 0.038
transcription from rna polymerase ii promoter GO:0006366 252 0.038
cation transport GO:0006812 382 0.038
positive regulation of neuron differentiation GO:0045666 126 0.037
macromolecular complex subunit organization GO:0043933 339 0.037
positive regulation of cell projection organization GO:0031346 111 0.037
single organism organelle organization GO:1902589 180 0.037
localization of cell GO:0051674 202 0.037
cellular response to oxygen containing compound GO:1901701 386 0.036
protein complex assembly GO:0006461 263 0.036
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.036
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 6 0.035
cell morphogenesis GO:0000902 142 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.035
single organism cellular localization GO:1902580 102 0.035
synaptic vesicle endocytosis GO:0048488 4 0.034
response to growth factor GO:0070848 189 0.034
positive regulation of rna metabolic process GO:0051254 203 0.034
vesicle mediated transport GO:0016192 181 0.034
positive regulation of synaptic transmission GO:0050806 62 0.034
secretion GO:0046903 307 0.034
protein oligomerization GO:0051259 191 0.034
cell motility GO:0048870 202 0.033
negative regulation of biosynthetic process GO:0009890 168 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
neuron projection morphogenesis GO:0048812 122 0.033
negative regulation of rna biosynthetic process GO:1902679 118 0.033
regulation of programmed cell death GO:0043067 341 0.033
cell projection morphogenesis GO:0048858 123 0.032
asymmetric protein localization GO:0008105 2 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
chemical homeostasis GO:0048878 292 0.032
neurotransmitter gated ion channel clustering GO:0072578 3 0.032
organelle localization GO:0051640 55 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.031
cellular catabolic process GO:0044248 295 0.031
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.031
cellular metal ion homeostasis GO:0006875 172 0.031
positive regulation of biosynthetic process GO:0009891 319 0.030
homeostatic process GO:0042592 331 0.030
apoptotic process GO:0006915 381 0.030
biological adhesion GO:0022610 110 0.030
anion transport GO:0006820 178 0.030
reproductive process GO:0022414 372 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
positive regulation of cell development GO:0010720 176 0.029
endocytosis GO:0006897 84 0.029
cardiac chamber development GO:0003205 1 0.028
divalent inorganic cation homeostasis GO:0072507 165 0.028
cellular response to organic cyclic compound GO:0071407 202 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
enzyme linked receptor protein signaling pathway GO:0007167 116 0.027
signal release GO:0023061 145 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.026
positive regulation of ion transport GO:0043270 94 0.026
cell fate commitment involved in pattern specification GO:0060581 2 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
positive regulation of gene expression GO:0010628 244 0.026
adult locomotory behavior GO:0008344 4 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.025
exocytosis GO:0006887 60 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
negative regulation of transcription dna templated GO:0045892 116 0.025
positive regulation of cell communication GO:0010647 271 0.025
multicellular organism reproduction GO:0032504 233 0.025
response to biotic stimulus GO:0009607 226 0.025
cellular macromolecule localization GO:0070727 122 0.025
growth GO:0040007 165 0.025
regulation of vesicle mediated transport GO:0060627 81 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
synapse organization GO:0050808 46 0.024
regulation of endocytosis GO:0030100 42 0.024
positive regulation of signal transduction GO:0009967 175 0.023
cellular amine metabolic process GO:0044106 38 0.023
regulation of protein metabolic process GO:0051246 289 0.023
sexual reproduction GO:0019953 148 0.023
cellular ion homeostasis GO:0006873 184 0.023
response to extracellular stimulus GO:0009991 380 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.022
protein heterooligomerization GO:0051291 89 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
dendritic spine development GO:0060996 20 0.022
nitrogen compound transport GO:0071705 229 0.022
salivary gland morphogenesis GO:0007435 1 0.022
embryonic skeletal system development GO:0048706 3 0.022
regulation of postsynaptic membrane potential GO:0060078 25 0.022
response to nutrient levels GO:0031667 370 0.022
cellular response to lipid GO:0071396 201 0.022
negative regulation of cell death GO:0060548 229 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
small gtpase mediated signal transduction GO:0007264 36 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
salivary gland development GO:0007431 3 0.021
ras protein signal transduction GO:0007265 29 0.021
receptor clustering GO:0043113 13 0.021
membrane depolarization GO:0051899 32 0.021
response to radiation GO:0009314 137 0.021
response to inorganic substance GO:0010035 377 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
ion homeostasis GO:0050801 212 0.021
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.021
multi organism reproductive process GO:0044703 262 0.020
positive regulation of cell death GO:0010942 184 0.020
negative regulation of transport GO:0051051 136 0.020
regeneration GO:0031099 163 0.020
regulation of ion transport GO:0043269 245 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.020
positive regulation of molecular function GO:0044093 230 0.020
protein localization to membrane GO:0072657 36 0.020
organophosphate metabolic process GO:0019637 370 0.019
regulation of synapse assembly GO:0051963 15 0.019
protein phosphorylation GO:0006468 345 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
single organism reproductive process GO:0044702 297 0.019
receptor mediated endocytosis GO:0006898 42 0.019
programmed cell death GO:0012501 392 0.019
establishment of tissue polarity GO:0007164 2 0.019
cellular protein localization GO:0034613 122 0.019
cellular cation homeostasis GO:0030003 180 0.019
hormone transport GO:0009914 121 0.019
negative regulation of molecular function GO:0044092 133 0.019
catabolic process GO:0009056 351 0.019
dendritic spine organization GO:0097061 12 0.018
regulation of ion transmembrane transporter activity GO:0032412 48 0.018
regulation of receptor internalization GO:0002090 6 0.018
organic anion transport GO:0015711 132 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
regulation of receptor mediated endocytosis GO:0048259 17 0.018
heart morphogenesis GO:0003007 3 0.018
carboxylic acid transport GO:0046942 115 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
organic substance catabolic process GO:1901575 316 0.017
single organism membrane organization GO:0044802 74 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
regulation of cellular component movement GO:0051270 150 0.017
rhythmic behavior GO:0007622 24 0.017
regulation of notch signaling pathway GO:0008593 3 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of membrane potential GO:0042391 110 0.017
developmental process involved in reproduction GO:0003006 159 0.017
regulation of proteasomal protein catabolic process GO:0061136 4 0.017
response to other organism GO:0051707 220 0.017
tissue development GO:0009888 252 0.016
reproduction GO:0000003 245 0.016
gamete generation GO:0007276 124 0.016
regulation of apoptotic process GO:0042981 335 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
response to bacterium GO:0009617 200 0.016
developmental growth GO:0048589 100 0.016
taxis GO:0042330 67 0.016
establishment of organelle localization GO:0051656 37 0.016
epithelial cell differentiation involved in kidney development GO:0035850 3 0.016
sensory perception GO:0007600 101 0.016
response to acid chemical GO:0001101 222 0.016
nucleotide metabolic process GO:0009117 279 0.016
response to toxic substance GO:0009636 133 0.016
jak stat cascade GO:0007259 26 0.016
regulation of cellular component biogenesis GO:0044087 86 0.016
amine metabolic process GO:0009308 38 0.016
regulation of cell cycle GO:0051726 73 0.016
response to purine containing compound GO:0014074 126 0.016
positive regulation of phosphorylation GO:0042327 177 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
actin filament based process GO:0030029 86 0.015
neuromuscular process GO:0050905 2 0.015
regulation of locomotion GO:0040012 148 0.015
head development GO:0060322 247 0.015
negative regulation of signaling GO:0023057 157 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
dephosphorylation GO:0016311 98 0.015
establishment of planar polarity GO:0001736 1 0.015
intracellular transport GO:0046907 185 0.015
regulation of transmembrane transporter activity GO:0022898 49 0.015
negative regulation of signal transduction GO:0009968 83 0.015
erbb signaling pathway GO:0038127 23 0.015
cellular response to acid chemical GO:0071229 75 0.015
nephric duct development GO:0072176 1 0.015
cell cycle process GO:0022402 57 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
purine containing compound metabolic process GO:0072521 253 0.014
immune response GO:0006955 104 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
cognition GO:0050890 92 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
glomerular epithelial cell differentiation GO:0072311 2 0.014
regulation of system process GO:0044057 208 0.014
cell migration GO:0016477 197 0.014
positive regulation of locomotion GO:0040017 102 0.014
cellular chemical homeostasis GO:0055082 247 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
regulation of hydrolase activity GO:0051336 143 0.014
receptor internalization GO:0031623 14 0.014
tissue morphogenesis GO:0048729 22 0.014
regulation of synaptic plasticity GO:0048167 70 0.014
single organism catabolic process GO:0044712 283 0.014
oxoacid metabolic process GO:0043436 290 0.014
cytoplasmic transport GO:0016482 115 0.014
response to metal ion GO:0010038 253 0.014
multicellular organismal reproductive process GO:0048609 233 0.013
chemotaxis GO:0006935 66 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
cell adhesion GO:0007155 110 0.013
organic acid metabolic process GO:0006082 292 0.013
cellular ketone metabolic process GO:0042180 51 0.013
hematopoietic progenitor cell differentiation GO:0002244 2 0.013
regulation of metal ion transport GO:0010959 118 0.013
locomotor rhythm GO:0045475 1 0.013
cellular homeostasis GO:0019725 252 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
membrane organization GO:0061024 94 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
response to nutrient GO:0007584 248 0.012
motor neuron axon guidance GO:0008045 1 0.012
regulation of protein modification process GO:0031399 194 0.012
embryonic skeletal system morphogenesis GO:0048704 3 0.012
protein localization to synapse GO:0035418 5 0.012
epidermal growth factor receptor signaling pathway GO:0007173 23 0.012
renal system development GO:0072001 67 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
divalent inorganic cation transport GO:0072511 134 0.012
developmental maturation GO:0021700 25 0.012
morphogenesis of a polarized epithelium GO:0001738 1 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
regulation of immune system process GO:0002682 123 0.012
amide transport GO:0042886 105 0.012
response to light stimulus GO:0009416 52 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
tube formation GO:0035148 3 0.012
calcium ion homeostasis GO:0055074 162 0.012
response to oxygen levels GO:0070482 265 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.011
ephrin receptor signaling pathway GO:0048013 3 0.011
learning or memory GO:0007611 90 0.011
kidney development GO:0001822 67 0.011
nucleoside metabolic process GO:0009116 179 0.011
epithelium development GO:0060429 96 0.011
synaptic vesicle exocytosis GO:0016079 15 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
response to gravity GO:0009629 13 0.011
bmp signaling pathway GO:0030509 4 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of transferase activity GO:0051338 123 0.011
kidney epithelium development GO:0072073 19 0.011
regulation of response to stress GO:0080134 126 0.011
inner ear morphogenesis GO:0042472 1 0.011
glomerular visceral epithelial cell differentiation GO:0072112 2 0.011
regulation of transporter activity GO:0032409 50 0.011
response to calcium ion GO:0051592 59 0.011
protein transport GO:0015031 132 0.011
response to ethanol GO:0045471 162 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
protein homooligomerization GO:0051260 91 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
gliogenesis GO:0042063 93 0.011
regulation of growth GO:0040008 105 0.011
regulation of insulin secretion GO:0050796 65 0.010
regulation of phosphorylation GO:0042325 248 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
cell differentiation involved in kidney development GO:0061005 4 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
rho protein signal transduction GO:0007266 11 0.010
wound healing GO:0042060 122 0.010
multi multicellular organism process GO:0044706 138 0.010
embryo development GO:0009790 49 0.010
response to decreased oxygen levels GO:0036293 237 0.010
cellular response to metal ion GO:0071248 55 0.010
response to wounding GO:0009611 254 0.010
establishment of protein localization GO:0045184 141 0.010
cellular response to inorganic substance GO:0071241 65 0.010
positive regulation of cell motility GO:2000147 97 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
response to magnesium ion GO:0032026 20 0.010
negative regulation of apoptotic process GO:0043066 181 0.010

Sdk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.014
disease of anatomical entity DOID:7 0 0.014