Rattus norvegicus

42 known processes

Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

Sema6c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 365 0.439
cation transport GO:0006812 382 0.152
regulation of nucleic acid templated transcription GO:1903506 380 0.149
cell projection morphogenesis GO:0048858 123 0.148
secretion by cell GO:0032940 248 0.141
regulation of membrane potential GO:0042391 110 0.139
learning or memory GO:0007611 90 0.132
neurological system process GO:0050877 219 0.131
Fly
transmembrane transport GO:0055085 412 0.091
negative regulation of metabolic process GO:0009892 331 0.088
neuron projection morphogenesis GO:0048812 122 0.088
cell part morphogenesis GO:0032990 123 0.087
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.082
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.079
rna metabolic process GO:0016070 406 0.074
positive regulation of cell proliferation GO:0008284 249 0.069
sensory perception GO:0007600 101 0.068
cellular component morphogenesis GO:0032989 155 0.068
negative regulation of cellular metabolic process GO:0031324 281 0.067
central nervous system development GO:0007417 311 0.065
Fly
carbohydrate derivative biosynthetic process GO:1901137 124 0.062
cation transmembrane transport GO:0098655 263 0.062
regulation of rna metabolic process GO:0051252 391 0.061
behavior GO:0007610 205 0.060
Fly
nucleic acid templated transcription GO:0097659 379 0.060
protein phosphorylation GO:0006468 345 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.058
glutamate receptor signaling pathway GO:0007215 43 0.058
regulation of secretion by cell GO:1903530 208 0.057
monovalent inorganic cation transport GO:0015672 172 0.057
anatomical structure morphogenesis GO:0009653 298 0.057
regulation of transcription dna templated GO:0006355 374 0.054
sensory perception of pain GO:0019233 73 0.054
metestrus GO:0060210 1 0.053
chemotaxis GO:0006935 66 0.052
positive regulation of rna metabolic process GO:0051254 203 0.052
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.051
single organism behavior GO:0044708 130 0.051
positive regulation of gene expression GO:0010628 244 0.051
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.050
transcription dna templated GO:0006351 377 0.050
regulation of secretion GO:0051046 224 0.049
positive regulation of rna biosynthetic process GO:1902680 197 0.049
metal ion homeostasis GO:0055065 186 0.046
positive regulation of transport GO:0051050 245 0.045
positive regulation of heart contraction GO:0045823 15 0.045
ribose phosphate biosynthetic process GO:0046390 87 0.044
regulation of ion transport GO:0043269 245 0.043
regulation of cellular localization GO:0060341 263 0.043
cell morphogenesis GO:0000902 142 0.042
cell cell signaling GO:0007267 335 0.042
nitrogen compound transport GO:0071705 229 0.041
positive regulation of biosynthetic process GO:0009891 319 0.041
transcription from rna polymerase ii promoter GO:0006366 252 0.040
ribonucleotide biosynthetic process GO:0009260 85 0.040
carbohydrate metabolic process GO:0005975 130 0.040
regulation of cell proliferation GO:0042127 359 0.040
secretion GO:0046903 307 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
single organism carbohydrate metabolic process GO:0044723 118 0.039
negative regulation of biosynthetic process GO:0009890 168 0.038
ribonucleotide metabolic process GO:0009259 231 0.037
cellular calcium ion homeostasis GO:0006874 160 0.037
regulation of anatomical structure morphogenesis GO:0022603 141 0.035
Rat Fly
regulation of rna biosynthetic process GO:2001141 381 0.035
synaptic transmission glutamatergic GO:0035249 33 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.035
dorsal ventral axon guidance GO:0033563 1 0.035
anion transport GO:0006820 178 0.035
nucleoside phosphate biosynthetic process GO:1901293 102 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
organophosphate metabolic process GO:0019637 370 0.034
calcium ion homeostasis GO:0055074 162 0.034
dicarboxylic acid transport GO:0006835 34 0.034
organonitrogen compound biosynthetic process GO:1901566 167 0.034
catabolic process GO:0009056 351 0.034
development of primary sexual characteristics GO:0045137 107 0.033
positive regulation of response to stimulus GO:0048584 285 0.033
gonad development GO:0008406 104 0.033
head development GO:0060322 247 0.032
Fly
cellular metal ion homeostasis GO:0006875 172 0.032
cellular cation homeostasis GO:0030003 180 0.031
negative regulation of transport GO:0051051 136 0.031
alcohol metabolic process GO:0006066 77 0.031
neuromuscular process GO:0050905 2 0.030
Fly
organ formation GO:0048645 3 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
cell projection organization GO:0030030 302 0.030
membrane organization GO:0061024 94 0.030
regulation of protein metabolic process GO:0051246 289 0.030
motor neuron axon guidance GO:0008045 1 0.029
Fly
regulation of cell projection organization GO:0031344 175 0.029
Rat Fly
reproductive process GO:0022414 372 0.029
regulation of cellular component organization GO:0051128 368 0.028
Rat Fly
single organism biosynthetic process GO:0044711 342 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
cytosolic calcium ion homeostasis GO:0051480 140 0.027
brain development GO:0007420 247 0.027
Fly
action potential GO:0001508 54 0.027
positive regulation of nucleotide metabolic process GO:0045981 91 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
reproductive system development GO:0061458 128 0.026
purine ribonucleotide biosynthetic process GO:0009152 81 0.026
establishment of tissue polarity GO:0007164 2 0.026
cyclic purine nucleotide metabolic process GO:0052652 62 0.025
single organism reproductive process GO:0044702 297 0.025
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.025
purine containing compound biosynthetic process GO:0072522 85 0.025
cyclic nucleotide biosynthetic process GO:0009190 63 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.025
Rat Fly
cellular component biogenesis GO:0044085 368 0.025
Fly
cellular response to oxygen containing compound GO:1901701 386 0.024
regulation of synaptic transmission GO:0050804 141 0.024
purine nucleotide biosynthetic process GO:0006164 83 0.024
organophosphate biosynthetic process GO:0090407 143 0.024
chemical homeostasis GO:0048878 292 0.024
regulation of nervous system development GO:0051960 264 0.023
Rat Fly
positive regulation of developmental process GO:0051094 283 0.023
heart development GO:0007507 72 0.023
urinary bladder smooth muscle contraction GO:0014832 4 0.023
nucleotide biosynthetic process GO:0009165 98 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
synaptic transmission GO:0007268 235 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.023
oxoacid metabolic process GO:0043436 290 0.023
regulation of peptide transport GO:0090087 87 0.023
sleep GO:0030431 30 0.022
positive regulation of protein kinase activity GO:0045860 73 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
positive regulation of signaling GO:0023056 270 0.022
regulation of anatomical structure size GO:0090066 135 0.022
Rat Fly
membrane depolarization GO:0051899 32 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.021
hormone transport GO:0009914 121 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 2 0.021
response to alkaloid GO:0043279 132 0.020
regulation of signal transduction GO:0009966 318 0.020
regulation of neuron projection development GO:0010975 161 0.020
Rat Fly
regulation of neurogenesis GO:0050767 247 0.020
Rat Fly
protein complex subunit organization GO:0071822 302 0.020
negative regulation of cellular component organization GO:0051129 83 0.020
Rat
positive regulation of cell development GO:0010720 176 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
positive regulation of protein modification process GO:0031401 142 0.019
vesicle mediated transport GO:0016192 181 0.019
cellular ketone metabolic process GO:0042180 51 0.019
ion homeostasis GO:0050801 212 0.019
cognition GO:0050890 92 0.019
negative regulation of gene expression GO:0010629 199 0.019
regulation of response to external stimulus GO:0032101 106 0.019
Fly
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
neuron projection development GO:0031175 273 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
camp metabolic process GO:0046058 63 0.018
response to hypoxia GO:0001666 231 0.018
organic acid metabolic process GO:0006082 292 0.018
negative regulation of secretion by cell GO:1903531 72 0.018
transmission of nerve impulse GO:0019226 42 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
regulation of lyase activity GO:0051339 22 0.018
regulation of response to stress GO:0080134 126 0.017
sodium ion transmembrane transport GO:0035725 67 0.017
urinary tract smooth muscle contraction GO:0014848 4 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
developmental growth GO:0048589 100 0.017
Rat
reproductive structure development GO:0048608 128 0.017
insulin secretion GO:0030073 69 0.017
growth GO:0040007 165 0.017
Rat
negative regulation of neuron differentiation GO:0045665 62 0.017
Rat
rna biosynthetic process GO:0032774 380 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
neuronal action potential GO:0019228 35 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
sex differentiation GO:0007548 113 0.017
salivary gland development GO:0007431 3 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.016
organic substance catabolic process GO:1901575 316 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
regulation of camp biosynthetic process GO:0030817 38 0.016
regulation of organ formation GO:0003156 2 0.016
regulation of molecular function GO:0065009 398 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
cellular chemical homeostasis GO:0055082 247 0.016
amide transport GO:0042886 105 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
cellular catabolic process GO:0044248 295 0.016
negative regulation of hormone secretion GO:0046888 46 0.016
memory GO:0007613 54 0.016
response to insulin GO:0032868 133 0.016
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.016
organic anion transport GO:0015711 132 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
negative regulation of dopamine secretion GO:0033602 4 0.015
cell proliferation in forebrain GO:0021846 3 0.015
cellular amine metabolic process GO:0044106 38 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
positive regulation of nervous system development GO:0051962 178 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
regulation of apoptotic process GO:0042981 335 0.015
heart contraction GO:0060047 57 0.015
cell cell signaling involved in cell fate commitment GO:0045168 2 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
regulation of organelle organization GO:0033043 80 0.015
mesoderm development GO:0007498 2 0.014
macromolecule localization GO:0033036 252 0.014
camp biosynthetic process GO:0006171 47 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
negative regulation of secretion GO:0051048 82 0.014
skeletal system development GO:0001501 41 0.014
phasic smooth muscle contraction GO:0014821 3 0.014
activation of protein kinase activity GO:0032147 47 0.014
endocytosis GO:0006897 84 0.014
regulation of nucleotide biosynthetic process GO:0030808 47 0.014
purine containing compound metabolic process GO:0072521 253 0.014
saliva secretion GO:0046541 3 0.014
sodium ion transport GO:0006814 82 0.014
carboxylic acid transport GO:0046942 115 0.014
positive regulation of peptide secretion GO:0002793 52 0.014
negative regulation of molecular function GO:0044092 133 0.014
regulation of receptor activity GO:0010469 29 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
regulation of interleukin 1 secretion GO:0050704 3 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
cation homeostasis GO:0055080 195 0.014
metal ion transport GO:0030001 289 0.013
programmed cell death GO:0012501 392 0.013
Rat
neuron development GO:0048666 286 0.013
glutamate secretion GO:0014047 19 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
signal release GO:0023061 145 0.013
negative regulation of signaling GO:0023057 157 0.013
regulation of growth GO:0040008 105 0.013
Rat
hormone secretion GO:0046879 115 0.013
regulation of heart contraction GO:0008016 48 0.013
male sex differentiation GO:0046661 64 0.013
gland development GO:0048732 155 0.013
positive regulation of organelle organization GO:0010638 48 0.013
synapse assembly GO:0007416 29 0.013
Fly
negative regulation of cell death GO:0060548 229 0.013
multicellular organism reproduction GO:0032504 233 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
multi organism reproductive process GO:0044703 262 0.012
nucleotide metabolic process GO:0009117 279 0.012
development of primary male sexual characteristics GO:0046546 59 0.012
regulation of cell development GO:0060284 263 0.012
Rat Fly
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.012
regeneration GO:0031099 163 0.012
tissue development GO:0009888 252 0.012
response to extracellular stimulus GO:0009991 380 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
positive regulation of peptide hormone secretion GO:0090277 50 0.012
developmental induction GO:0031128 2 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
neuron differentiation GO:0030182 368 0.012
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
positive regulation of ion transport GO:0043270 94 0.012
developmental process involved in reproduction GO:0003006 159 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
Rat Fly
male gonad development GO:0008584 59 0.012
negative regulation of cell projection organization GO:0031345 50 0.012
Rat
negative regulation of cell communication GO:0010648 158 0.012
organelle organization GO:0006996 266 0.012
lipid storage GO:0019915 1 0.011
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.011
carbohydrate catabolic process GO:0016052 40 0.011
positive regulation of molecular function GO:0044093 230 0.011
female sex differentiation GO:0046660 59 0.011
regulation of hormone secretion GO:0046883 106 0.011
dendrite morphogenesis GO:0048813 43 0.011
Fly
eating behavior GO:0042755 21 0.011
aging GO:0007568 241 0.011
positive regulation of cell communication GO:0010647 271 0.011
regulation of neuron differentiation GO:0045664 208 0.011
Rat Fly
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
response to amphetamine GO:0001975 25 0.011
regulation of camp metabolic process GO:0030814 43 0.011
somatostatin receptor signaling pathway GO:0038169 4 0.011
regulation of system process GO:0044057 208 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
peristalsis GO:0030432 2 0.011
single organism catabolic process GO:0044712 283 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
cell cycle checkpoint GO:0000075 2 0.011
multicellular organismal reproductive process GO:0048609 233 0.010
cellular component assembly GO:0022607 360 0.010
Fly
estrous cycle phase GO:0060206 15 0.010
thigmotaxis GO:0001966 1 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.010
regulation of cellular protein metabolic process GO:0032268 267 0.010
positive regulation of action potential GO:0045760 8 0.010
regulation of glutamate receptor signaling pathway GO:1900449 17 0.010
regulation of hormone levels GO:0010817 187 0.010
reproduction GO:0000003 245 0.010
epithelial cell differentiation GO:0030855 71 0.010
multicellular organismal signaling GO:0035637 44 0.010
dendrite development GO:0016358 72 0.010
Fly
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
circulatory system development GO:0072359 134 0.010
male gamete generation GO:0048232 99 0.010
defense response GO:0006952 194 0.010

Sema6c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.013
disease of anatomical entity DOID:7 0 0.013