Rattus norvegicus

60 known processes

Senp2

Sumo1/sentrin/SMT3 specific peptidase 2

(Aliases: Axam)

Senp2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cell communication GO:0010647 271 0.169
cellular catabolic process GO:0044248 295 0.141
organic acid metabolic process GO:0006082 292 0.109
cellular response to luteinizing hormone stimulus GO:0071373 5 0.105
intracellular signal transduction GO:0035556 314 0.103
ubiquitin dependent protein catabolic process GO:0006511 14 0.099
protein modification by small protein conjugation or removal GO:0070647 35 0.095
Human
positive regulation of signaling GO:0023056 270 0.093
response to uv c GO:0010225 2 0.091
oxoacid metabolic process GO:0043436 290 0.086
organic substance catabolic process GO:1901575 316 0.085
macromolecular complex assembly GO:0065003 273 0.081
macromolecule localization GO:0033036 252 0.079
protein phosphorylation GO:0006468 345 0.072
dna metabolic process GO:0006259 96 0.072
regulation of phosphorus metabolic process GO:0051174 349 0.066
growth GO:0040007 165 0.065
cellular protein localization GO:0034613 122 0.065
single organism cellular localization GO:1902580 102 0.064
regulation of phosphorylation GO:0042325 248 0.063
anterior posterior pattern specification GO:0009952 1 0.061
negative regulation of signaling GO:0023057 157 0.061
regulation of signal transduction GO:0009966 318 0.060
catabolic process GO:0009056 351 0.059
regulation of kinase activity GO:0043549 117 0.059
organophosphate metabolic process GO:0019637 370 0.058
carboxylic acid metabolic process GO:0019752 289 0.055
regulation of catalytic activity GO:0050790 304 0.055
regulation of protein phosphorylation GO:0001932 183 0.055
reproductive process GO:0022414 372 0.051
response to growth factor GO:0070848 189 0.050
small gtpase mediated signal transduction GO:0007264 36 0.050
positive regulation of protein metabolic process GO:0051247 178 0.050
regulation of glycoprotein biosynthetic process GO:0010559 6 0.049
positive regulation of biosynthetic process GO:0009891 319 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.047
negative regulation of rna biosynthetic process GO:1902679 118 0.046
regulation of protein metabolic process GO:0051246 289 0.046
cellular macromolecule localization GO:0070727 122 0.045
positive regulation of phosphorylation GO:0042327 177 0.043
embryonic pattern specification GO:0009880 1 0.043
nucleocytoplasmic transport GO:0006913 48 0.043
dicarboxylic acid metabolic process GO:0043648 42 0.042
regulation of protein modification process GO:0031399 194 0.041
protein complex subunit organization GO:0071822 302 0.041
regulation of cellular component organization GO:0051128 368 0.041
cytoplasmic transport GO:0016482 115 0.039
cellular component biogenesis GO:0044085 368 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
cell projection morphogenesis GO:0048858 123 0.038
regulation of molecular function GO:0065009 398 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.038
positive regulation of response to stimulus GO:0048584 285 0.037
establishment of protein localization GO:0045184 141 0.037
nucleoside phosphate metabolic process GO:0006753 283 0.037
alpha amino acid catabolic process GO:1901606 20 0.037
cellular ion homeostasis GO:0006873 184 0.036
purine nucleotide metabolic process GO:0006163 229 0.036
cellular cation homeostasis GO:0030003 180 0.035
positive regulation of cell proliferation GO:0008284 249 0.035
cell cycle GO:0007049 101 0.035
regulation of membrane potential GO:0042391 110 0.035
cellular response to growth factor stimulus GO:0071363 162 0.034
embryonic axis specification GO:0000578 1 0.034
single organism reproductive process GO:0044702 297 0.034
positive regulation of signal transduction GO:0009967 175 0.034
ribose phosphate metabolic process GO:0019693 235 0.034
positive regulation of mapk cascade GO:0043410 92 0.034
cation transport GO:0006812 382 0.034
cellular response to stress GO:0033554 269 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.033
cellular response to abiotic stimulus GO:0071214 85 0.033
positive regulation of intracellular signal transduction GO:1902533 138 0.033
muscle system process GO:0003012 115 0.033
nucleic acid templated transcription GO:0097659 379 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
metal ion transport GO:0030001 289 0.032
acetyl coa metabolic process GO:0006084 17 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
single organism intracellular transport GO:1902582 166 0.032
cell part morphogenesis GO:0032990 123 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
protein modification by small protein conjugation GO:0032446 31 0.032
nucleoside monophosphate metabolic process GO:0009123 93 0.031
protein localization GO:0008104 191 0.031
response to radiation GO:0009314 137 0.030
protein targeting GO:0006605 61 0.030
negative regulation of transcription dna templated GO:0045892 116 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.030
neurological system process GO:0050877 219 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
secretion GO:0046903 307 0.029
chemical homeostasis GO:0048878 292 0.028
secretion by cell GO:0032940 248 0.028
intracellular transport GO:0046907 185 0.028
organelle organization GO:0006996 266 0.028
regulation of cell cycle GO:0051726 73 0.027
ion homeostasis GO:0050801 212 0.026
protein complex biogenesis GO:0070271 263 0.026
regulation of respiratory gaseous exchange GO:0043576 2 0.026
transcription dna templated GO:0006351 377 0.026
protein complex assembly GO:0006461 263 0.025
homeostatic process GO:0042592 331 0.025
wnt signaling pathway GO:0016055 17 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
cation homeostasis GO:0055080 195 0.024
axis specification GO:0009798 4 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
response to extracellular stimulus GO:0009991 380 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
cellular protein catabolic process GO:0044257 19 0.023
divalent inorganic cation transport GO:0072511 134 0.023
ribonucleoside catabolic process GO:0042454 126 0.023
glycosyl compound catabolic process GO:1901658 126 0.023
mitotic cell cycle GO:0000278 49 0.023
regulation of transferase activity GO:0051338 123 0.023
positive regulation of membrane potential GO:0045838 16 0.023
protein ubiquitination GO:0016567 28 0.023
vesicle mediated transport GO:0016192 181 0.023
positive regulation of dna metabolic process GO:0051054 39 0.023
ribonucleotide catabolic process GO:0009261 136 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
purine nucleoside monophosphate catabolic process GO:0009128 55 0.022
nuclear transport GO:0051169 49 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
multi organism reproductive process GO:0044703 262 0.022
sexual reproduction GO:0019953 148 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
divalent metal ion transport GO:0070838 132 0.021
programmed cell death GO:0012501 392 0.021
negative regulation of cell communication GO:0010648 158 0.021
transmembrane transport GO:0055085 412 0.021
protein oligomerization GO:0051259 191 0.021
proteolysis GO:0006508 175 0.021
Human
cellular amino acid metabolic process GO:0006520 107 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
regulation of protein transport GO:0051223 68 0.020
regulation of protein kinase activity GO:0045859 105 0.020
reproduction GO:0000003 245 0.020
lipid transport GO:0006869 61 0.020
intracellular protein transport GO:0006886 79 0.020
cell cycle process GO:0022402 57 0.019
single organism catabolic process GO:0044712 283 0.019
cellular component morphogenesis GO:0032989 155 0.019
regulation of neurogenesis GO:0050767 247 0.019
regulation of hydrolase activity GO:0051336 143 0.019
positive regulation of molecular function GO:0044093 230 0.019
neuronal action potential GO:0019228 35 0.019
protein transport GO:0015031 132 0.019
peristalsis GO:0030432 2 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
establishment of protein localization to organelle GO:0072594 44 0.018
regulation of nervous system development GO:0051960 264 0.018
response to nutrient levels GO:0031667 370 0.018
rna metabolic process GO:0016070 406 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
developmental process involved in reproduction GO:0003006 159 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
protein catabolic process GO:0030163 30 0.017
positive regulation of protein modification process GO:0031401 142 0.017
alpha amino acid metabolic process GO:1901605 71 0.017
meiotic cell cycle process GO:1903046 3 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
regulation of small gtpase mediated signal transduction GO:0051056 48 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
cell cell signaling GO:0007267 335 0.017
cytoskeleton organization GO:0007010 111 0.017
negative regulation of metabolic process GO:0009892 331 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
gtp catabolic process GO:0006184 71 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
cellular homeostasis GO:0019725 252 0.016
protein autophosphorylation GO:0046777 66 0.016
modification dependent macromolecule catabolic process GO:0043632 14 0.016
negative regulation of molecular function GO:0044092 133 0.016
cardiovascular system development GO:0072358 134 0.016
chromosome segregation GO:0007059 2 0.016
cellular component assembly GO:0022607 360 0.016
regulation of transcription dna templated GO:0006355 374 0.016
purine nucleoside monophosphate metabolic process GO:0009126 84 0.016
cellular amine metabolic process GO:0044106 38 0.016
ras protein signal transduction GO:0007265 29 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
ephrin receptor signaling pathway GO:0048013 3 0.015
purine containing compound metabolic process GO:0072521 253 0.015
potassium ion transport GO:0006813 97 0.015
aromatic compound catabolic process GO:0019439 168 0.015
nucleotide metabolic process GO:0009117 279 0.015
multicellular organism reproduction GO:0032504 233 0.014
acetyl coa biosynthetic process GO:0006085 6 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
regulation of postsynaptic membrane potential GO:0060078 25 0.014
cellular response to oxidative stress GO:0034599 76 0.014
neuron development GO:0048666 286 0.014
response to oxidative stress GO:0006979 186 0.014
purine nucleoside catabolic process GO:0006152 124 0.014
receptor localization to synapse GO:0097120 2 0.014
neurotransmitter gated ion channel clustering GO:0072578 3 0.014
positive regulation of gene expression GO:0010628 244 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
mapk cascade GO:0000165 140 0.014
meiosis i GO:0007127 2 0.014
regulation of cell proliferation GO:0042127 359 0.014
regulation of cellular localization GO:0060341 263 0.014
dephosphorylation GO:0016311 98 0.014
nucleoside metabolic process GO:0009116 179 0.013
metal ion homeostasis GO:0055065 186 0.013
response to biotic stimulus GO:0009607 226 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.013
activation of mapkkk activity GO:0000185 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
regulation of dna metabolic process GO:0051052 60 0.013
embryonic skeletal system morphogenesis GO:0048704 3 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
p38mapk cascade GO:0038066 1 0.013
positive regulation of developmental process GO:0051094 283 0.013
reproductive structure development GO:0048608 128 0.013
rna biosynthetic process GO:0032774 380 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
cellular chemical homeostasis GO:0055082 247 0.013
regulation of metal ion transport GO:0010959 118 0.013
locomotion GO:0040011 237 0.013
negative regulation of receptor internalization GO:0002091 2 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
single organism organelle organization GO:1902589 180 0.013
lipid metabolic process GO:0006629 283 0.013
spermatogenesis GO:0007283 99 0.013
circulatory system development GO:0072359 134 0.013
cell projection organization GO:0030030 302 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
spindle organization GO:0007051 2 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
regulation of secretion GO:0051046 224 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
ncrna processing GO:0034470 3 0.012
cellular response to metal ion GO:0071248 55 0.012
maintenance of location GO:0051235 17 0.012
cell cycle checkpoint GO:0000075 2 0.012
regulation of hormone levels GO:0010817 187 0.012
deoxyribonucleotide metabolic process GO:0009262 9 0.012
cell motility GO:0048870 202 0.012
reproductive system development GO:0061458 128 0.012
cofactor metabolic process GO:0051186 95 0.012
single organism nuclear import GO:1902593 35 0.012
regulation of erk1 and erk2 cascade GO:0070372 41 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
male gamete generation GO:0048232 99 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
transmission of nerve impulse GO:0019226 42 0.012
gamete generation GO:0007276 124 0.012
regulation of mapk cascade GO:0043408 116 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
protein homooligomerization GO:0051260 91 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
immune response GO:0006955 104 0.012
regulation of jnk cascade GO:0046328 19 0.012
negative regulation of catalytic activity GO:0043086 103 0.011
embryo development GO:0009790 49 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
ribonucleoside monophosphate catabolic process GO:0009158 55 0.011
rho protein signal transduction GO:0007266 11 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
cell morphogenesis GO:0000902 142 0.011
rna localization GO:0006403 4 0.011
neuron projection guidance GO:0097485 24 0.011
neuron projection development GO:0031175 273 0.011
heterocycle catabolic process GO:0046700 167 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
deoxyribonucleoside triphosphate metabolic process GO:0009200 6 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
macromolecule catabolic process GO:0009057 58 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
dendrite development GO:0016358 72 0.011
actin filament based process GO:0030029 86 0.011
regulation of rna metabolic process GO:0051252 391 0.011
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
regulation of programmed cell death GO:0043067 341 0.011
cell growth GO:0016049 104 0.011
neuronal ion channel clustering GO:0045161 3 0.011
regulation of calcium ion transport GO:0051924 77 0.011
positive regulation of dendritic spine morphogenesis GO:0061003 3 0.011
cellular ketone metabolic process GO:0042180 51 0.010
2 deoxyribonucleotide metabolic process GO:0009394 9 0.010
immune system process GO:0002376 204 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
regulation of hormone secretion GO:0046883 106 0.010
locomotor rhythm GO:0045475 1 0.010
cellular amino acid catabolic process GO:0009063 21 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
developmental growth GO:0048589 100 0.010
deoxyribose phosphate metabolic process GO:0019692 9 0.010
dendritic spine development GO:0060996 20 0.010

Senp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.010
musculoskeletal system disease DOID:17 0 0.010