Rattus norvegicus

0 known processes

Serpinb12

serpin peptidase inhibitor, clade B (ovalbumin), member 12

(Aliases: RGD1566382)

Serpinb12 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular biosynthetic process GO:0031328 295 0.134
transmembrane transport GO:0055085 412 0.121
macromolecule localization GO:0033036 252 0.099
response to inorganic substance GO:0010035 377 0.095
organ morphogenesis GO:0009887 75 0.086
single organism biosynthetic process GO:0044711 342 0.086
Rat
regulation of rna metabolic process GO:0051252 391 0.084
ossification GO:0001503 70 0.084
regulation of nucleic acid templated transcription GO:1903506 380 0.083
epithelial cell proliferation GO:0050673 54 0.082
macromolecular complex assembly GO:0065003 273 0.079
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.078
Rat
negative regulation of rna metabolic process GO:0051253 123 0.077
regulation of rna biosynthetic process GO:2001141 381 0.076
anatomical structure morphogenesis GO:0009653 298 0.075
tissue development GO:0009888 252 0.074
Rat
rna metabolic process GO:0016070 406 0.072
transcription from rna polymerase ii promoter GO:0006366 252 0.070
apoptotic process GO:0006915 381 0.069
regulation of anatomical structure morphogenesis GO:0022603 141 0.067
regulation of cell differentiation GO:0045595 320 0.065
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.064
cellular component morphogenesis GO:0032989 155 0.064
regulation of protein modification process GO:0031399 194 0.062
negative regulation of rna biosynthetic process GO:1902679 118 0.059
cellular ion homeostasis GO:0006873 184 0.058
regulation of growth GO:0040008 105 0.057
positive regulation of cell proliferation GO:0008284 249 0.057
Rat
cellular component biogenesis GO:0044085 368 0.056
negative regulation of cellular metabolic process GO:0031324 281 0.055
Human Rat
negative regulation of gene expression GO:0010629 199 0.055
Human Rat
neuron development GO:0048666 286 0.055
response to extracellular stimulus GO:0009991 380 0.054
embryonic appendage morphogenesis GO:0035113 4 0.054
positive regulation of phosphate metabolic process GO:0045937 262 0.054
regulation of metal ion transport GO:0010959 118 0.052
head development GO:0060322 247 0.050
negative regulation of nucleic acid templated transcription GO:1903507 117 0.050
positive regulation of protein phosphorylation GO:0001934 135 0.050
cellular component assembly GO:0022607 360 0.049
homeostatic process GO:0042592 331 0.049
protein oligomerization GO:0051259 191 0.048
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.048
protein phosphorylation GO:0006468 345 0.047
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.046
organic acid metabolic process GO:0006082 292 0.045
brain development GO:0007420 247 0.043
positive regulation of gene expression GO:0010628 244 0.043
lipid metabolic process GO:0006629 283 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.041
negative regulation of cellular biosynthetic process GO:0031327 161 0.041
sensory perception GO:0007600 101 0.039
positive regulation of phosphorus metabolic process GO:0010562 262 0.039
wound healing GO:0042060 122 0.039
Rat
response to hypoxia GO:0001666 231 0.038
positive regulation of biosynthetic process GO:0009891 319 0.038
Rat
protein complex biogenesis GO:0070271 263 0.037
protein complex subunit organization GO:0071822 302 0.036
behavior GO:0007610 205 0.035
lipid biosynthetic process GO:0008610 128 0.035
negative regulation of biosynthetic process GO:0009890 168 0.035
central nervous system development GO:0007417 311 0.035
embryonic hindlimb morphogenesis GO:0035116 2 0.034
rna biosynthetic process GO:0032774 380 0.034
positive regulation of response to stimulus GO:0048584 285 0.033
programmed cell death GO:0012501 392 0.032
detection of chemical stimulus GO:0009593 10 0.031
steroid metabolic process GO:0008202 73 0.031
positive regulation of mapk cascade GO:0043410 92 0.031
amine metabolic process GO:0009308 38 0.031
response to estrogen GO:0043627 232 0.031
organic anion transport GO:0015711 132 0.031
positive regulation of protein kinase activity GO:0045860 73 0.030
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
cell projection morphogenesis GO:0048858 123 0.030
forebrain development GO:0030900 98 0.030
hepaticobiliary system development GO:0061008 90 0.030
positive regulation of kinase activity GO:0033674 77 0.029
hindlimb morphogenesis GO:0035137 2 0.029
positive regulation of protein metabolic process GO:0051247 178 0.029
regulation of blood vessel size GO:0050880 89 0.029
response to estradiol GO:0032355 164 0.029
appendage morphogenesis GO:0035107 4 0.029
response to decreased oxygen levels GO:0036293 237 0.029
cellular amine metabolic process GO:0044106 38 0.029
carboxylic acid metabolic process GO:0019752 289 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
regulation of secretion by cell GO:1903530 208 0.028
neuron projection development GO:0031175 273 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
cytokine mediated signaling pathway GO:0019221 43 0.027
neurological system process GO:0050877 219 0.027
nucleic acid templated transcription GO:0097659 379 0.026
signal transduction by phosphorylation GO:0023014 144 0.026
response to wounding GO:0009611 254 0.026
Rat
regulation of protein metabolic process GO:0051246 289 0.025
Human Rat
organ induction GO:0001759 1 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
establishment of protein localization GO:0045184 141 0.025
vascular process in circulatory system GO:0003018 96 0.025
negative regulation of long term synaptic potentiation GO:1900272 1 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
regulation of organ formation GO:0003156 2 0.024
positive regulation of signal transduction GO:0009967 175 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
cellular response to stress GO:0033554 269 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
negative regulation of cell proliferation GO:0008285 119 0.022
sodium ion transport GO:0006814 82 0.022
cellular protein localization GO:0034613 122 0.022
regulation of transporter activity GO:0032409 50 0.022
protein complex assembly GO:0006461 263 0.022
cation homeostasis GO:0055080 195 0.021
cation transmembrane transport GO:0098655 263 0.021
protein localization GO:0008104 191 0.021
negative regulation of chronic inflammatory response GO:0002677 2 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
positive regulation of transcription dna templated GO:0045893 197 0.021
limb morphogenesis GO:0035108 4 0.021
regulation of phosphorylation GO:0042325 248 0.020
immune system process GO:0002376 204 0.020
Mouse
inorganic ion transmembrane transport GO:0098660 229 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
regulation of establishment of protein localization GO:0070201 69 0.020
glycerolipid metabolic process GO:0046486 67 0.020
cellular chemical homeostasis GO:0055082 247 0.020
secretion GO:0046903 307 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.019
regulation of protein kinase activity GO:0045859 105 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
regulation of epithelial cell proliferation GO:0050678 49 0.019
metal ion transport GO:0030001 289 0.019
estrous cycle phase GO:0060206 15 0.019
cell cell signaling involved in cell fate commitment GO:0045168 2 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
regulation of apoptotic process GO:0042981 335 0.019
oxoacid metabolic process GO:0043436 290 0.019
response to peptide hormone GO:0043434 278 0.019
cell adhesion GO:0007155 110 0.018
circulatory system process GO:0003013 183 0.018
regulation of transcription dna templated GO:0006355 374 0.018
response to vitamin GO:0033273 131 0.018
developmental process involved in reproduction GO:0003006 159 0.018
cellular macromolecule localization GO:0070727 122 0.018
transcription dna templated GO:0006351 377 0.018
organophosphate metabolic process GO:0019637 370 0.017
cell part morphogenesis GO:0032990 123 0.017
neuromuscular process GO:0050905 2 0.017
response to reactive oxygen species GO:0000302 120 0.017
cell morphogenesis GO:0000902 142 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
regulation of regulatory t cell differentiation GO:0045589 2 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
Human Rat
organelle organization GO:0006996 266 0.017
regulation of signal transduction GO:0009966 318 0.017
regeneration GO:0031099 163 0.017
blood circulation GO:0008015 183 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
regulation of mapk cascade GO:0043408 116 0.016
cellular ketone metabolic process GO:0042180 51 0.016
peptidyl tyrosine modification GO:0018212 72 0.016
response to nutrient levels GO:0031667 370 0.016
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.016
developmental induction GO:0031128 2 0.016
neuron differentiation GO:0030182 368 0.016
single organism organelle organization GO:1902589 180 0.016
l glutamate import GO:0051938 2 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
Rat
muscle structure development GO:0061061 87 0.016
sensory perception of bitter taste GO:0050913 4 0.016
gland development GO:0048732 155 0.016
positive regulation of developmental process GO:0051094 283 0.016
Rat
regulation of cardiac muscle tissue development GO:0055024 12 0.016
single organism cell adhesion GO:0098602 46 0.015
regulation of ossification GO:0030278 32 0.015
endoplasmic reticulum organization GO:0007029 1 0.015
response to toxic substance GO:0009636 133 0.015
positive regulation of renin secretion into blood stream GO:1900135 1 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
regulation of cell proliferation GO:0042127 359 0.015
Rat
gamete generation GO:0007276 124 0.015
single organism behavior GO:0044708 130 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
angioblast cell migration GO:0035476 1 0.015
synapse organization GO:0050808 46 0.015
mapk cascade GO:0000165 140 0.015
cell cycle GO:0007049 101 0.015
chemical homeostasis GO:0048878 292 0.014
regulation of transmembrane transporter activity GO:0022898 49 0.014
regulation of immune system process GO:0002682 123 0.014
liver development GO:0001889 90 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
biological adhesion GO:0022610 110 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
ion transmembrane transport GO:0034220 365 0.014
aging GO:0007568 241 0.014
rho protein signal transduction GO:0007266 11 0.014
growth GO:0040007 165 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
locomotor rhythm GO:0045475 1 0.013
regulation of protein localization GO:0032880 81 0.013
regulation of osteoblast differentiation GO:0045667 14 0.013
reproductive process GO:0022414 372 0.013
calcium ion transport GO:0006816 131 0.013
cellular response to estradiol stimulus GO:0071392 16 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
peptidyl amino acid modification GO:0018193 126 0.013
negative regulation of cell death GO:0060548 229 0.013
neuron projection morphogenesis GO:0048812 122 0.013
positive regulation of transferase activity GO:0051347 81 0.013
calcium ion homeostasis GO:0055074 162 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
cellular modified amino acid metabolic process GO:0006575 61 0.013
positive regulation of cardiac muscle tissue development GO:0055025 9 0.013
regulation of anatomical structure size GO:0090066 135 0.012
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
bone development GO:0060348 25 0.012
regulation of hormone levels GO:0010817 187 0.012
cell growth GO:0016049 104 0.012
intracellular signal transduction GO:0035556 314 0.012
cellular homeostasis GO:0019725 252 0.012
prostate gland morphogenesis GO:0060512 2 0.012
synapse assembly GO:0007416 29 0.012
negative regulation of neutrophil apoptotic process GO:0033030 3 0.012
cation transport GO:0006812 382 0.012
negative regulation of metabolic process GO:0009892 331 0.012
Human Rat
sexual reproduction GO:0019953 148 0.012
multi organism reproductive process GO:0044703 262 0.012
regulation of cell projection organization GO:0031344 175 0.012
epithelial cell differentiation GO:0030855 71 0.012
skeletal system development GO:0001501 41 0.012
endochondral ossification GO:0001958 2 0.011
regulation of protein transport GO:0051223 68 0.011
regulation of sodium ion transport GO:0002028 21 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
mammary gland epithelium development GO:0061180 1 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
regulation of blood circulation GO:1903522 110 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.011
regulation of chronic inflammatory response GO:0002676 3 0.011
lipid storage GO:0019915 1 0.011
multicellular organismal homeostasis GO:0048871 49 0.011
glucose homeostasis GO:0042593 75 0.011
regulation of cellular component organization GO:0051128 368 0.011
muscle organ development GO:0007517 50 0.011
ras protein signal transduction GO:0007265 29 0.011
reproductive structure development GO:0048608 128 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
neutrophil apoptotic process GO:0001781 4 0.011
regulation of cardiac muscle tissue growth GO:0055021 12 0.011
axis specification GO:0009798 4 0.011
response to metal ion GO:0010038 253 0.011
organic acid transport GO:0015849 116 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
cell cell signaling GO:0007267 335 0.010
detection of stimulus GO:0051606 24 0.010
negative regulation of developmental process GO:0051093 125 0.010
metanephric tubule development GO:0072170 4 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
positive regulation of protein modification process GO:0031401 142 0.010
oxidation reduction process GO:0055114 304 0.010
multicellular organism reproduction GO:0032504 233 0.010
organ formation GO:0048645 3 0.010
regulation of multicellular organismal development GO:2000026 376 0.010
Rat
defense response to gram negative bacterium GO:0050829 3 0.010

Serpinb12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
urinary system disease DOID:18 0 0.012
renal tubular transport disease DOID:447 0 0.012
kidney disease DOID:557 0 0.012