Rattus norvegicus

0 known processes

Serpinb3a

serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A

(Aliases: RGD1562868)

Serpinb3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to reactive oxygen species GO:0000302 120 0.207
negative regulation of metabolic process GO:0009892 331 0.149
Human Mouse Rat
cellular response to glucocorticoid stimulus GO:0071385 68 0.136
cellular response to hormone stimulus GO:0032870 247 0.113
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.110
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.105
reproductive process GO:0022414 372 0.104
nucleoside phosphate biosynthetic process GO:1901293 102 0.103
negative regulation of immune response to tumor cell GO:0002838 2 0.093
ribonucleotide biosynthetic process GO:0009260 85 0.087
central nervous system development GO:0007417 311 0.082
negative regulation of response to tumor cell GO:0002835 2 0.082
ribonucleotide metabolic process GO:0009259 231 0.079
response to tumor cell GO:0002347 4 0.079
intracellular signal transduction GO:0035556 314 0.078
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.078
regulation of body fluid levels GO:0050878 90 0.077
single organism reproductive process GO:0044702 297 0.074
regulation of multicellular organismal development GO:2000026 376 0.073
Rat
response to ketone GO:1901654 182 0.071
negative regulation of macromolecule metabolic process GO:0010605 260 0.067
Human Mouse Rat
purine nucleotide metabolic process GO:0006163 229 0.065
tissue development GO:0009888 252 0.065
Rat
positive regulation of biosynthetic process GO:0009891 319 0.064
Rat
regulation of cell differentiation GO:0045595 320 0.064
rna metabolic process GO:0016070 406 0.063
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.063
negative regulation of rna biosynthetic process GO:1902679 118 0.062
purine ribonucleotide metabolic process GO:0009150 227 0.062
carboxylic acid metabolic process GO:0019752 289 0.061
regulation of molecular function GO:0065009 398 0.061
Human Mouse Rat
carbohydrate derivative metabolic process GO:1901135 346 0.061
cellular response to endogenous stimulus GO:0071495 377 0.060
regulation of rna metabolic process GO:0051252 391 0.060
response to estrogen GO:0043627 232 0.060
single organism cell adhesion GO:0098602 46 0.058
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.057
response to nutrient levels GO:0031667 370 0.057
gland development GO:0048732 155 0.055
multi organism reproductive process GO:0044703 262 0.055
cellular response to peptide hormone stimulus GO:0071375 120 0.053
ribose phosphate biosynthetic process GO:0046390 87 0.053
negative regulation of response to stimulus GO:0048585 155 0.052
single organismal cell cell adhesion GO:0016337 42 0.052
negative regulation of molecular function GO:0044092 133 0.051
Human Mouse Rat
negative regulation of biosynthetic process GO:0009890 168 0.051
multi multicellular organism process GO:0044706 138 0.050
regulation of neurogenesis GO:0050767 247 0.049
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.049
negative regulation of cellular metabolic process GO:0031324 281 0.048
Human Mouse Rat
regulation of immune response to tumor cell GO:0002837 3 0.048
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.048
negative regulation of cellular biosynthetic process GO:0031327 161 0.047
response to inorganic substance GO:0010035 377 0.047
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.047
regulation of response to tumor cell GO:0002834 3 0.045
regulation of cell development GO:0060284 263 0.045
negative regulation of rna metabolic process GO:0051253 123 0.045
negative regulation of transcription dna templated GO:0045892 116 0.044
regulation of nucleotide metabolic process GO:0006140 117 0.044
response to ethanol GO:0045471 162 0.044
anterior posterior pattern specification GO:0009952 1 0.043
transcription dna templated GO:0006351 377 0.043
response to extracellular stimulus GO:0009991 380 0.043
organic acid metabolic process GO:0006082 292 0.042
nucleobase containing small molecule metabolic process GO:0055086 316 0.042
purine ribonucleotide biosynthetic process GO:0009152 81 0.042
salivary gland morphogenesis GO:0007435 1 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.041
Human Mouse Rat
positive regulation of multicellular organismal process GO:0051240 387 0.041
Rat
oxoacid metabolic process GO:0043436 290 0.040
rna biosynthetic process GO:0032774 380 0.040
cyclic nucleotide metabolic process GO:0009187 80 0.040
circulatory system process GO:0003013 183 0.040
response to oxidative stress GO:0006979 186 0.040
ribose phosphate metabolic process GO:0019693 235 0.040
transcription from rna polymerase ii promoter GO:0006366 252 0.039
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
regulation of rna biosynthetic process GO:2001141 381 0.039
cyclic purine nucleotide metabolic process GO:0052652 62 0.039
negative regulation of gene expression GO:0010629 199 0.038
Human Mouse Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.037
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.036
regulation of cyclase activity GO:0031279 21 0.036
regulation of transcription dna templated GO:0006355 374 0.036
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.036
purine containing compound metabolic process GO:0072521 253 0.036
negative regulation of cell death GO:0060548 229 0.036
cellular response to corticosteroid stimulus GO:0071384 69 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.034
epithelium development GO:0060429 96 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
glycosyl compound catabolic process GO:1901658 126 0.034
response to acid chemical GO:0001101 222 0.034
positive regulation of transcription dna templated GO:0045893 197 0.033
negative regulation of developmental process GO:0051093 125 0.033
response to nutrient GO:0007584 248 0.033
regulation of cellular component organization GO:0051128 368 0.033
purine containing compound biosynthetic process GO:0072522 85 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.033
cellular nitrogen compound catabolic process GO:0044270 163 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
female pregnancy GO:0007565 122 0.032
ribonucleoside metabolic process GO:0009119 174 0.032
response to peptide hormone GO:0043434 278 0.031
intracellular transport GO:0046907 185 0.031
epithelial cell differentiation GO:0030855 71 0.031
cellular response to nitrogen compound GO:1901699 210 0.031
cellular ketone metabolic process GO:0042180 51 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
positive regulation of cell differentiation GO:0045597 217 0.030
immune response to tumor cell GO:0002418 3 0.029
cellular response to organic cyclic compound GO:0071407 202 0.029
regulation of catalytic activity GO:0050790 304 0.029
Human Mouse Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.028
regulation of protein modification process GO:0031399 194 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
nucleotide biosynthetic process GO:0009165 98 0.028
positive regulation of gene expression GO:0010628 244 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
rhythmic process GO:0048511 156 0.027
liver development GO:0001889 90 0.027
cgmp biosynthetic process GO:0006182 15 0.026
negative regulation of phosphate metabolic process GO:0045936 80 0.026
regulation of hydrolase activity GO:0051336 143 0.026
Human Mouse Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.026
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
nucleotide metabolic process GO:0009117 279 0.025
fatty acid derivative metabolic process GO:1901568 38 0.025
response to peptide GO:1901652 292 0.025
purine containing compound catabolic process GO:0072523 138 0.025
muscle structure development GO:0061061 87 0.025
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.025
cellular response to steroid hormone stimulus GO:0071383 93 0.025
regulation of programmed cell death GO:0043067 341 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
reproduction GO:0000003 245 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
multicellular organism reproduction GO:0032504 233 0.024
negative regulation of innate immune response GO:0045824 4 0.024
apoptotic process GO:0006915 381 0.024
neuronal action potential GO:0019228 35 0.024
purine nucleotide biosynthetic process GO:0006164 83 0.024
glycosyl compound metabolic process GO:1901657 182 0.023
lipid metabolic process GO:0006629 283 0.023
nucleoside triphosphate metabolic process GO:0009141 144 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
Rat
multicellular organismal signaling GO:0035637 44 0.023
striated muscle cell development GO:0055002 26 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
positive regulation of developmental process GO:0051094 283 0.022
Rat
regulation of phosphate metabolic process GO:0019220 349 0.022
urogenital system development GO:0001655 78 0.022
Rat
positive regulation of molecular function GO:0044093 230 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.022
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.022
cyclic nucleotide biosynthetic process GO:0009190 63 0.022
nucleoside metabolic process GO:0009116 179 0.022
purine nucleoside metabolic process GO:0042278 169 0.021
purine ribonucleotide catabolic process GO:0009154 136 0.021
negative regulation of cell differentiation GO:0045596 99 0.021
leukocyte cell cell adhesion GO:0007159 4 0.021
regulation of nucleotide biosynthetic process GO:0030808 47 0.021
axis specification GO:0009798 4 0.021
response to decreased oxygen levels GO:0036293 237 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
brain development GO:0007420 247 0.021
single organism organelle organization GO:1902589 180 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
protein localization GO:0008104 191 0.021
cellular response to acid chemical GO:0071229 75 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
amine metabolic process GO:0009308 38 0.021
regulation of apoptotic process GO:0042981 335 0.020
negative regulation of cell communication GO:0010648 158 0.020
protein phosphorylation GO:0006468 345 0.020
response to oxygen levels GO:0070482 265 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
negative regulation of signaling GO:0023057 157 0.020
regulation of cell proliferation GO:0042127 359 0.020
Rat
organophosphate metabolic process GO:0019637 370 0.020
regulation of stem cell differentiation GO:2000736 2 0.020
purine nucleoside triphosphate catabolic process GO:0009146 122 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
organophosphate catabolic process GO:0046434 148 0.020
head development GO:0060322 247 0.020
ribonucleotide catabolic process GO:0009261 136 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
protein transport GO:0015031 132 0.019
ribonucleoside triphosphate catabolic process GO:0009203 122 0.019
positive regulation of nucleotide metabolic process GO:0045981 91 0.019
endocytosis GO:0006897 84 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
regulation of nervous system development GO:0051960 264 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
response to glucocorticoid GO:0051384 223 0.019
regeneration GO:0031099 163 0.019
cation homeostasis GO:0055080 195 0.019
embryonic pattern specification GO:0009880 1 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
coagulation GO:0050817 28 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
response to testosterone GO:0033574 55 0.019
nucleotide catabolic process GO:0009166 139 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
negative regulation of cell development GO:0010721 82 0.018
blood circulation GO:0008015 183 0.018
single organism biosynthetic process GO:0044711 342 0.018
Rat
regulation of cell activation GO:0050865 50 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
salivary gland development GO:0007431 3 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
positive regulation of immune response GO:0050778 42 0.018
positive regulation of signaling GO:0023056 270 0.018
regulation of protein transport GO:0051223 68 0.018
regulation of protein metabolic process GO:0051246 289 0.018
Human Mouse Rat
response to growth factor GO:0070848 189 0.017
regulation of response to external stimulus GO:0032101 106 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
response to metal ion GO:0010038 253 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
nephric duct development GO:0072176 1 0.016
response to wounding GO:0009611 254 0.016
Rat
inflammatory response GO:0006954 150 0.016
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.016
hepaticobiliary system development GO:0061008 90 0.016
regulation of defense response GO:0031347 68 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
single organism cellular localization GO:1902580 102 0.016
cytoplasmic transport GO:0016482 115 0.016
nucleic acid templated transcription GO:0097659 379 0.016
cellular response to peptide GO:1901653 133 0.016
peptidyl tyrosine modification GO:0018212 72 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
cellular amine metabolic process GO:0044106 38 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.016
response to hydrogen peroxide GO:0042542 89 0.015
b cell differentiation GO:0030183 2 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
chemical homeostasis GO:0048878 292 0.015
response to dexamethasone GO:0071548 49 0.015
kidney development GO:0001822 67 0.015
Rat
macromolecular complex subunit organization GO:0043933 339 0.015
reproductive structure development GO:0048608 128 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
metanephric s shaped body morphogenesis GO:0072284 2 0.015
response to corticosteroid GO:0031960 235 0.015
heart morphogenesis GO:0003007 3 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
cell part morphogenesis GO:0032990 123 0.015
cardiac chamber development GO:0003205 1 0.015
regulation of protein kinase activity GO:0045859 105 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
response to mineralocorticoid GO:0051385 49 0.015
embryonic axis specification GO:0000578 1 0.014
circadian rhythm GO:0007623 88 0.014
g protein coupled receptor internalization GO:0002031 3 0.014
macromolecule localization GO:0033036 252 0.014
response to insulin GO:0032868 133 0.014
response to vitamin GO:0033273 131 0.014
cellular response to stress GO:0033554 269 0.014
cellular lipid metabolic process GO:0044255 208 0.014
muscle tissue development GO:0060537 58 0.014
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.014
growth GO:0040007 165 0.014
positive regulation of protein kinase activity GO:0045860 73 0.014
reproductive system development GO:0061458 128 0.014
proteolysis GO:0006508 175 0.014
Human Mouse Rat
metanephric comma shaped body morphogenesis GO:0072278 2 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
Human Mouse Rat
response to organophosphorus GO:0046683 102 0.014
neuron projection development GO:0031175 273 0.014
intracellular protein transport GO:0006886 79 0.014
metanephric glomerulus development GO:0072224 3 0.014
cytoskeleton organization GO:0007010 111 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
molting cycle process GO:0022404 2 0.014
response to toxic substance GO:0009636 133 0.013
cell cell signaling GO:0007267 335 0.013
behavior GO:0007610 205 0.013
comma shaped body morphogenesis GO:0072049 2 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
regulation of transferase activity GO:0051338 123 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
myosin filament assembly GO:0031034 1 0.013
synaptic transmission GO:0007268 235 0.013
aromatic compound catabolic process GO:0019439 168 0.013
tube development GO:0035295 89 0.013
organelle organization GO:0006996 266 0.013
positive regulation of synaptic transmission GO:0050806 62 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
molting cycle GO:0042303 3 0.013
regulation of signal transduction GO:0009966 318 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
positive regulation of cell communication GO:0010647 271 0.013
metal ion homeostasis GO:0055065 186 0.013
cellular component morphogenesis GO:0032989 155 0.013
regulation of protein serine threonine kinase activity GO:0071900 64 0.013
kidney morphogenesis GO:0060993 13 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
cellular protein localization GO:0034613 122 0.013
organ regeneration GO:0031100 101 0.013
cellular component biogenesis GO:0044085 368 0.013
negative regulation of signal transduction GO:0009968 83 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
negative regulation of catalytic activity GO:0043086 103 0.012
Human Mouse Rat
negative regulation of multicellular organismal process GO:0051241 203 0.012
defense response GO:0006952 194 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
cell fate determination GO:0001709 2 0.012
negative regulation of response to biotic stimulus GO:0002832 4 0.012
regulation of response to wounding GO:1903034 69 0.012
regulation of membrane potential GO:0042391 110 0.012
positive regulation of transferase activity GO:0051347 81 0.012
jak stat cascade GO:0007259 26 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
muscle cell differentiation GO:0042692 52 0.012
developmental process involved in reproduction GO:0003006 159 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
single organism intracellular transport GO:1902582 166 0.012
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
regulation of cellular component movement GO:0051270 150 0.012
ras protein signal transduction GO:0007265 29 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.011
macromolecular complex assembly GO:0065003 273 0.011
glial cell development GO:0021782 19 0.011
regulation of muscle system process GO:0090257 79 0.011
hair cycle GO:0042633 3 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
camp biosynthetic process GO:0006171 47 0.011
cellular component assembly GO:0022607 360 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
response to hypoxia GO:0001666 231 0.011
muscle cell development GO:0055001 26 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
biological adhesion GO:0022610 110 0.011
hair cycle process GO:0022405 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
Human Mouse Rat
calcium ion homeostasis GO:0055074 162 0.011
transmission of nerve impulse GO:0019226 42 0.011
heterocycle catabolic process GO:0046700 167 0.011
blood coagulation GO:0007596 26 0.011
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.011
gliogenesis GO:0042063 93 0.011
nucleoside catabolic process GO:0009164 126 0.011
regulation of system process GO:0044057 208 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
homeostatic process GO:0042592 331 0.011
cellular response to alcohol GO:0097306 87 0.011
peptidyl amino acid modification GO:0018193 126 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
cytokine mediated signaling pathway GO:0019221 43 0.011
nucleocytoplasmic transport GO:0006913 48 0.010
response to radiation GO:0009314 137 0.010
s shaped body morphogenesis GO:0072050 2 0.010
mesonephros development GO:0001823 14 0.010
programmed cell death GO:0012501 392 0.010
cellular response to insulin stimulus GO:0032869 81 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
response to cadmium ion GO:0046686 35 0.010
response to axon injury GO:0048678 59 0.010
cell projection morphogenesis GO:0048858 123 0.010
neural crest cell differentiation GO:0014033 2 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
fractalkine metabolic process GO:0050756 3 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
regulation of response to stress GO:0080134 126 0.010
positive regulation of kinase activity GO:0033674 77 0.010
negative regulation of defense response GO:0031348 19 0.010
regulation of kinase activity GO:0043549 117 0.010

Serpinb3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.016
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014