Rattus norvegicus

0 known processes

Serpinb6a

serine (or cysteine) peptidase inhibitor, clade B, member 6a

(Aliases: MGC72983,Serpinb6)

Serpinb6a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecule localization GO:0033036 252 0.356
cellular lipid metabolic process GO:0044255 208 0.346
positive regulation of programmed cell death GO:0043068 157 0.217
positive regulation of cell death GO:0010942 184 0.199
positive regulation of apoptotic process GO:0043065 154 0.197
regulation of cell proliferation GO:0042127 359 0.169
Rat
regulation of cellular component organization GO:0051128 368 0.157
cation transport GO:0006812 382 0.157
lipid metabolic process GO:0006629 283 0.155
organic acid biosynthetic process GO:0016053 83 0.151
apoptotic process GO:0006915 381 0.141
regulation of programmed cell death GO:0043067 341 0.126
endomembrane system organization GO:0010256 48 0.124
monocarboxylic acid metabolic process GO:0032787 152 0.122
protein localization GO:0008104 191 0.115
single organism intracellular transport GO:1902582 166 0.113
small molecule biosynthetic process GO:0044283 124 0.112
fatty acid metabolic process GO:0006631 99 0.111
regulation of apoptotic process GO:0042981 335 0.102
oxoacid metabolic process GO:0043436 290 0.101
cellular component biogenesis GO:0044085 368 0.097
regulation of wound healing GO:0061041 14 0.096
positive regulation of transport GO:0051050 245 0.091
single organism membrane organization GO:0044802 74 0.088
purine containing compound metabolic process GO:0072521 253 0.088
gliogenesis GO:0042063 93 0.087
membrane organization GO:0061024 94 0.086
organic substance catabolic process GO:1901575 316 0.085
regulation of secretion GO:0051046 224 0.084
cellular component movement GO:0006928 248 0.083
synaptic transmission GO:0007268 235 0.082
metal ion transport GO:0030001 289 0.079
response to estradiol GO:0032355 164 0.078
establishment of protein localization GO:0045184 141 0.078
locomotion GO:0040011 237 0.077
positive regulation of cell proliferation GO:0008284 249 0.077
Rat
secretion GO:0046903 307 0.077
localization of cell GO:0051674 202 0.076
cell motility GO:0048870 202 0.074
regulation of ion transport GO:0043269 245 0.074
cellular protein localization GO:0034613 122 0.074
intracellular transport GO:0046907 185 0.073
response to zinc ion GO:0010043 39 0.073
regulation of molecular function GO:0065009 398 0.072
Human Rat
programmed cell death GO:0012501 392 0.071
regulation of catalytic activity GO:0050790 304 0.071
Human Rat
establishment of protein localization to membrane GO:0090150 16 0.068
protein localization to membrane GO:0072657 36 0.067
exocytosis GO:0006887 60 0.065
response to metal ion GO:0010038 253 0.064
regulation of secretion by cell GO:1903530 208 0.062
anatomical structure morphogenesis GO:0009653 298 0.062
brain development GO:0007420 247 0.060
negative regulation of phospholipase a2 activity GO:1900138 1 0.058
ribonucleoside triphosphate catabolic process GO:0009203 122 0.057
response to transition metal nanoparticle GO:1990267 122 0.057
secretion by cell GO:0032940 248 0.057
fatty acid derivative metabolic process GO:1901568 38 0.054
organic acid metabolic process GO:0006082 292 0.052
vesicle mediated transport GO:0016192 181 0.052
inorganic ion transmembrane transport GO:0098660 229 0.052
cellular response to corticosteroid stimulus GO:0071384 69 0.050
central nervous system development GO:0007417 311 0.050
organophosphate metabolic process GO:0019637 370 0.050
icosanoid biosynthetic process GO:0046456 18 0.050
single organism biosynthetic process GO:0044711 342 0.050
Rat
negative regulation of secretion GO:0051048 82 0.048
negative regulation of multicellular organismal process GO:0051241 203 0.048
negative regulation of secretion by cell GO:1903531 72 0.048
response to nutrient GO:0007584 248 0.048
plasma membrane organization GO:0007009 17 0.047
golgi vesicle transport GO:0048193 22 0.047
regulation of blood coagulation GO:0030193 9 0.046
unsaturated fatty acid biosynthetic process GO:0006636 21 0.046
ion transmembrane transport GO:0034220 365 0.045
cation transmembrane transport GO:0098655 263 0.045
single organism reproductive process GO:0044702 297 0.045
response to estrogen GO:0043627 232 0.044
response to decreased oxygen levels GO:0036293 237 0.044
protein complex biogenesis GO:0070271 263 0.043
ribonucleotide metabolic process GO:0009259 231 0.042
protein transport GO:0015031 132 0.042
nitrogen compound transport GO:0071705 229 0.041
negative regulation of transport GO:0051051 136 0.041
reproductive process GO:0022414 372 0.041
membrane fusion GO:0061025 26 0.041
regulation of phosphorus metabolic process GO:0051174 349 0.041
response to corticosteroid GO:0031960 235 0.041
heterocycle catabolic process GO:0046700 167 0.040
cellular component assembly GO:0022607 360 0.040
carboxylic acid biosynthetic process GO:0046394 83 0.040
epithelium development GO:0060429 96 0.040
response to inorganic substance GO:0010035 377 0.040
single organism cellular localization GO:1902580 102 0.040
cellular macromolecule localization GO:0070727 122 0.039
organonitrogen compound catabolic process GO:1901565 179 0.039
cell cell signaling GO:0007267 335 0.038
intracellular protein transport GO:0006886 79 0.038
neuron differentiation GO:0030182 368 0.038
cellular nitrogen compound catabolic process GO:0044270 163 0.037
regulation of response to external stimulus GO:0032101 106 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.036
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.035
protein targeting to membrane GO:0006612 11 0.035
positive regulation of signaling GO:0023056 270 0.035
purine nucleotide metabolic process GO:0006163 229 0.035
catabolic process GO:0009056 351 0.035
neuron development GO:0048666 286 0.034
purine ribonucleotide catabolic process GO:0009154 136 0.033
cellular response to glucocorticoid stimulus GO:0071385 68 0.033
multi organism reproductive process GO:0044703 262 0.033
nucleotide metabolic process GO:0009117 279 0.033
ribonucleoside triphosphate metabolic process GO:0009199 141 0.033
regulation of hormone levels GO:0010817 187 0.033
peptide secretion GO:0002790 86 0.033
regulation of metal ion transport GO:0010959 118 0.033
cellular response to oxygen containing compound GO:1901701 386 0.032
purine nucleoside triphosphate catabolic process GO:0009146 122 0.032
inorganic cation transmembrane transport GO:0098662 202 0.032
positive regulation of phosphate metabolic process GO:0045937 262 0.032
hormone transport GO:0009914 121 0.031
positive regulation of response to stimulus GO:0048584 285 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
protein complex assembly GO:0006461 263 0.031
regulation of cell adhesion GO:0030155 52 0.031
cell migration GO:0016477 197 0.031
skeletal muscle cell differentiation GO:0035914 2 0.030
cellular response to stress GO:0033554 269 0.030
hemostasis GO:0007599 26 0.030
response to glucocorticoid GO:0051384 223 0.030
inflammatory response GO:0006954 150 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
positive regulation of molecular function GO:0044093 230 0.029
regulation of cell differentiation GO:0045595 320 0.029
glycosyl compound catabolic process GO:1901658 126 0.029
divalent inorganic cation transport GO:0072511 134 0.029
long term synaptic potentiation GO:0060291 21 0.028
telencephalon development GO:0021537 62 0.028
nucleoside phosphate catabolic process GO:1901292 140 0.028
fatty acid biosynthetic process GO:0006633 33 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
regulation of rna metabolic process GO:0051252 391 0.028
regulation of response to stress GO:0080134 126 0.028
unsaturated fatty acid metabolic process GO:0033559 39 0.028
cellular catabolic process GO:0044248 295 0.028
transmembrane transport GO:0055085 412 0.028
purine containing compound catabolic process GO:0072523 138 0.028
acute inflammatory response GO:0002526 58 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.027
signal release GO:0023061 145 0.027
regulation of hemostasis GO:1900046 9 0.027
dna geometric change GO:0032392 4 0.027
response to extracellular stimulus GO:0009991 380 0.027
organic cyclic compound catabolic process GO:1901361 175 0.027
protein complex subunit organization GO:0071822 302 0.027
negative regulation of metabolic process GO:0009892 331 0.027
Human Rat
calcium ion transport GO:0006816 131 0.027
positive regulation of phosphorylation GO:0042327 177 0.026
purine nucleoside catabolic process GO:0006152 124 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
carboxylic acid metabolic process GO:0019752 289 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
negative regulation of developmental process GO:0051093 125 0.026
peptide transport GO:0015833 97 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
regulation of establishment of protein localization GO:0070201 69 0.026
protein phosphorylation GO:0006468 345 0.026
protein targeting to plasma membrane GO:0072661 4 0.025
glial cell differentiation GO:0010001 65 0.025
response to biotic stimulus GO:0009607 226 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
positive regulation of signal transduction GO:0009967 175 0.025
regulation of coagulation GO:0050818 11 0.025
response to calcium ion GO:0051592 59 0.024
amide transport GO:0042886 105 0.024
regulation of cellular localization GO:0060341 263 0.024
lipid biosynthetic process GO:0008610 128 0.024
endosomal transport GO:0016197 14 0.024
chemical homeostasis GO:0048878 292 0.024
anion transport GO:0006820 178 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
regulation of lipid biosynthetic process GO:0046890 38 0.024
cellular response to organic cyclic compound GO:0071407 202 0.024
protein localization to plasma membrane GO:0072659 15 0.023
response to cytokine GO:0034097 215 0.023
response to hypoxia GO:0001666 231 0.023
limbic system development GO:0021761 38 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
regulation of body fluid levels GO:0050878 90 0.023
multicellular organism reproduction GO:0032504 233 0.023
head development GO:0060322 247 0.023
reproductive system development GO:0061458 128 0.023
neuronal action potential GO:0019228 35 0.023
regulation of protein transport GO:0051223 68 0.023
purine nucleotide catabolic process GO:0006195 136 0.023
cell projection organization GO:0030030 302 0.023
homeostatic process GO:0042592 331 0.023
hormone secretion GO:0046879 115 0.023
aromatic compound catabolic process GO:0019439 168 0.023
fatty acid derivative biosynthetic process GO:1901570 18 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of membrane potential GO:0042391 110 0.022
divalent metal ion transport GO:0070838 132 0.022
intracellular signal transduction GO:0035556 314 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
ribonucleoside catabolic process GO:0042454 126 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
regulation of catabolic process GO:0009894 113 0.021
monocarboxylic acid biosynthetic process GO:0072330 48 0.021
regulation of synaptic transmission GO:0050804 141 0.021
peptide hormone secretion GO:0030072 84 0.021
organ regeneration GO:0031100 101 0.021
response to radiation GO:0009314 137 0.021
regulation of fatty acid biosynthetic process GO:0042304 7 0.020
neuron projection development GO:0031175 273 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
cellular response to lipid GO:0071396 201 0.020
transcription dna templated GO:0006351 377 0.020
positive regulation of developmental process GO:0051094 283 0.020
Rat
macromolecular complex assembly GO:0065003 273 0.020
ion homeostasis GO:0050801 212 0.019
nucleoside metabolic process GO:0009116 179 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
positive regulation of cell communication GO:0010647 271 0.019
regulation of synaptic plasticity GO:0048167 70 0.019
organophosphate catabolic process GO:0046434 148 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
regulation of protein localization GO:0032880 81 0.019
leukotriene biosynthetic process GO:0019370 3 0.019
nucleotide catabolic process GO:0009166 139 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
regulation of fatty acid metabolic process GO:0019217 18 0.019
regulation of cell development GO:0060284 263 0.019
dna strand renaturation GO:0000733 1 0.019
cellular ketone metabolic process GO:0042180 51 0.019
regulation of transcription dna templated GO:0006355 374 0.018
regulation of skeletal muscle cell differentiation GO:2001014 1 0.018
icosanoid metabolic process GO:0006690 38 0.018
response to vitamin GO:0033273 131 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
tissue development GO:0009888 252 0.018
Rat
female pregnancy GO:0007565 122 0.018
negative regulation of nervous system development GO:0051961 79 0.018
gland development GO:0048732 155 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
positive regulation of ion transport GO:0043270 94 0.018
response to oxidative stress GO:0006979 186 0.017
cellular response to steroid hormone stimulus GO:0071383 93 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
Rat
regeneration GO:0031099 163 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
protein oligomerization GO:0051259 191 0.017
purine nucleoside monophosphate catabolic process GO:0009128 55 0.017
forebrain development GO:0030900 98 0.017
aging GO:0007568 241 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
regulation of phosphorylation GO:0042325 248 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
positive regulation of fibroblast proliferation GO:0048146 15 0.016
reproduction GO:0000003 245 0.016
action potential GO:0001508 54 0.016
negative regulation of hemostasis GO:1900047 6 0.016
single organism catabolic process GO:0044712 283 0.016
nucleic acid templated transcription GO:0097659 379 0.016
positive regulation of synaptic transmission GO:0050806 62 0.016
dna conformation change GO:0071103 10 0.016
regulation of response to wounding GO:1903034 69 0.015
prolactin secretion GO:0070459 2 0.015
nucleoside catabolic process GO:0009164 126 0.015
response to glucose GO:0009749 136 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
multi multicellular organism process GO:0044706 138 0.015
regulation of neuron differentiation GO:0045664 208 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
regulation of protein metabolic process GO:0051246 289 0.015
Human Rat
purine nucleoside monophosphate metabolic process GO:0009126 84 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.015
negative regulation of response to external stimulus GO:0032102 37 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
atp metabolic process GO:0046034 72 0.014
cell chemotaxis GO:0060326 31 0.014
response to growth factor GO:0070848 189 0.014
cellular response to hypoxia GO:0071456 51 0.014
cell type specific apoptotic process GO:0097285 134 0.014
regulation of protein modification process GO:0031399 194 0.014
regulation of neurogenesis GO:0050767 247 0.014
immune system process GO:0002376 204 0.014
axon development GO:0061564 96 0.014
epithelial cell differentiation GO:0030855 71 0.014
multicellular organismal signaling GO:0035637 44 0.014
response to carbohydrate GO:0009743 183 0.014
response to ethanol GO:0045471 162 0.014
negative regulation of molecular function GO:0044092 133 0.014
Human Rat
multicellular organismal reproductive process GO:0048609 233 0.014
hepatocyte differentiation GO:0070365 8 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
protein targeting GO:0006605 61 0.013
dna rewinding GO:0036292 1 0.013
hippocampus development GO:0021766 30 0.013
biological adhesion GO:0022610 110 0.013
regulation of transmembrane transport GO:0034762 122 0.013
behavior GO:0007610 205 0.013
endocrine system development GO:0035270 30 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
Human Rat
coagulation GO:0050817 28 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
response to oxygen levels GO:0070482 265 0.013
cytoplasmic transport GO:0016482 115 0.013
blood coagulation GO:0007596 26 0.013
transmission of nerve impulse GO:0019226 42 0.013
gamete generation GO:0007276 124 0.013
pallium development GO:0021543 42 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
regulation of dna metabolic process GO:0051052 60 0.013
lipid localization GO:0010876 62 0.013
atp catabolic process GO:0006200 54 0.013
nucleoside monophosphate catabolic process GO:0009125 56 0.013
growth GO:0040007 165 0.012
cellular response to oxygen levels GO:0071453 60 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
vesicle fusion GO:0006906 14 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
positive regulation of catabolic process GO:0009896 78 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
single organism behavior GO:0044708 130 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
negative regulation of lipase activity GO:0060192 3 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
regulation of calcium ion transport GO:0051924 77 0.012
positive regulation of transmembrane transport GO:0034764 25 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
response to monosaccharide GO:0034284 159 0.012
response to nutrient levels GO:0031667 370 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
regulation of locomotion GO:0040012 148 0.012
wound healing GO:0042060 122 0.012
Rat
positive regulation of calcium ion transport GO:0051928 36 0.011
response to peptide hormone GO:0043434 278 0.011
organic anion transport GO:0015711 132 0.011
regulation of phospholipase a2 activity GO:0032429 1 0.011
response to external biotic stimulus GO:0043207 221 0.011
organelle organization GO:0006996 266 0.011
prostaglandin metabolic process GO:0006693 12 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
response to light stimulus GO:0009416 52 0.011
ras protein signal transduction GO:0007265 29 0.011
urogenital system development GO:0001655 78 0.011
Rat
cellular ion homeostasis GO:0006873 184 0.011
dna duplex unwinding GO:0032508 3 0.011
developmental process involved in reproduction GO:0003006 159 0.011
erythrocyte differentiation GO:0030218 1 0.011
lipid transport GO:0006869 61 0.011
response to bacterium GO:0009617 200 0.011
response to ionizing radiation GO:0010212 59 0.011
chronic inflammatory response GO:0002544 16 0.010
male gamete generation GO:0048232 99 0.010
cellular amine metabolic process GO:0044106 38 0.010
estrous cycle phase GO:0060206 15 0.010
dna metabolic process GO:0006259 96 0.010
amine metabolic process GO:0009308 38 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
glucose homeostasis GO:0042593 75 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
response to other organism GO:0051707 220 0.010
negative regulation of cell differentiation GO:0045596 99 0.010

Serpinb6a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021