Rattus norvegicus

311 known processes

Serpine1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

(Aliases: Pai1aa,PAI1A,Pai1,Planh,RATPAI1A)

Serpine1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cell migration GO:0030335 96 0.907
positive regulation of locomotion GO:0040017 102 0.885
cell motility GO:0048870 202 0.810
apoptotic process GO:0006915 381 0.733
Human
positive regulation of cell motility GO:2000147 97 0.673
response to wounding GO:0009611 254 0.663
regulation of programmed cell death GO:0043067 341 0.661
Human
response to peptide GO:1901652 292 0.616
negative regulation of cell death GO:0060548 229 0.608
Human
response to corticosteroid GO:0031960 235 0.603
response to temperature stimulus GO:0009266 94 0.584
regulation of cellular component movement GO:0051270 150 0.552
response to interleukin 1 GO:0070555 55 0.513
locomotion GO:0040011 237 0.512
ovulation GO:0030728 17 0.511
single organism reproductive process GO:0044702 297 0.500
positive regulation of response to stimulus GO:0048584 285 0.475
Human
cellular response to high density lipoprotein particle stimulus GO:0071403 2 0.475
regulation of nucleic acid templated transcription GO:1903506 380 0.468
positive regulation of cellular component movement GO:0051272 102 0.461
regulation of cell proliferation GO:0042127 359 0.447
regulation of signal transduction GO:0009966 318 0.447
Human
response to estrogen GO:0043627 232 0.424
cellular response to organic cyclic compound GO:0071407 202 0.422
positive regulation of multicellular organismal process GO:0051240 387 0.420
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.402
response to biotic stimulus GO:0009607 226 0.401
regeneration GO:0031099 163 0.400
response to inorganic substance GO:0010035 377 0.397
cellular response to interleukin 1 GO:0071347 37 0.385
cellular response to cytokine stimulus GO:0071345 127 0.383
programmed cell death GO:0012501 392 0.378
Human
localization of cell GO:0051674 202 0.374
response to lipopolysaccharide GO:0032496 191 0.367
positive regulation of cell communication GO:0010647 271 0.362
cellular response to endogenous stimulus GO:0071495 377 0.357
cellular response to stress GO:0033554 269 0.357
blood vessel development GO:0001568 69 0.351
Human Mouse
response to bacterium GO:0009617 200 0.339
response to estradiol GO:0032355 164 0.337
response to acid chemical GO:0001101 222 0.331
response to oxygen levels GO:0070482 265 0.330
regulation of leukocyte migration GO:0002685 24 0.325
Human
regulation of locomotion GO:0040012 148 0.323
positive regulation of smooth muscle cell migration GO:0014911 27 0.314
reproductive process GO:0022414 372 0.314
response to cytokine GO:0034097 215 0.313
response to extracellular stimulus GO:0009991 380 0.310
response to dexamethasone GO:0071548 49 0.309
cell chemotaxis GO:0060326 31 0.308
Human
cellular response to hormone stimulus GO:0032870 247 0.305
negative regulation of cell proliferation GO:0008285 119 0.302
response to vitamin GO:0033273 131 0.301
wound healing GO:0042060 122 0.301
response to amino acid GO:0043200 75 0.298
regulation of cell differentiation GO:0045595 320 0.297
Rat
positive regulation of signaling GO:0023056 270 0.297
cellular response to glucocorticoid stimulus GO:0071385 68 0.283
circulatory system development GO:0072359 134 0.282
Human Mouse
reproduction GO:0000003 245 0.280
response to heat GO:0009408 60 0.278
response to tumor necrosis factor GO:0034612 56 0.276
cellular response to drug GO:0035690 30 0.273
response to molecule of bacterial origin GO:0002237 194 0.270
regulation of apoptotic process GO:0042981 335 0.267
Human
positive regulation of fever generation GO:0031622 5 0.265
anatomical structure morphogenesis GO:0009653 298 0.259
Human Mouse
carbohydrate derivative metabolic process GO:1901135 346 0.258
regulation of fever generation GO:0031620 6 0.255
regulation of cellular component organization GO:0051128 368 0.254
response to nutrient levels GO:0031667 370 0.252
nucleic acid templated transcription GO:0097659 379 0.250
tissue development GO:0009888 252 0.250
negative regulation of programmed cell death GO:0043069 183 0.247
Human
transcription dna templated GO:0006351 377 0.246
cellular component biogenesis GO:0044085 368 0.244
Rat
response to hypoxia GO:0001666 231 0.236
response to indole 3 methanol GO:0071680 2 0.236
leukocyte migration GO:0050900 38 0.235
Human
response to mechanical stimulus GO:0009612 134 0.230
cellular component movement GO:0006928 248 0.226
positive regulation of synaptic plasticity GO:0031915 3 0.222
multi multicellular organism process GO:0044706 138 0.221
positive regulation of neuron projection development GO:0010976 99 0.220
Rat
cell migration GO:0016477 197 0.220
muscle cell migration GO:0014812 36 0.216
Human
transformation of host cell by virus GO:0019087 4 0.216
catabolic process GO:0009056 351 0.209
Rat
regulation of angiogenesis GO:0045765 39 0.204
Human Mouse
positive regulation of cell proliferation GO:0008284 249 0.203
cellular response to oxygen containing compound GO:1901701 386 0.201
response to other organism GO:0051707 220 0.201
transcription from rna polymerase ii promoter GO:0006366 252 0.199
regulation of immune system process GO:0002682 123 0.199
Human
cellular response to lipoteichoic acid GO:0071223 1 0.197
positive regulation of g0 to g1 transition GO:0070318 2 0.195
positive regulation of phosphorus metabolic process GO:0010562 262 0.195
response to high density lipoprotein particle GO:0055099 2 0.194
multicellular organism reproduction GO:0032504 233 0.190
response to decreased oxygen levels GO:0036293 237 0.190
vasculature development GO:0001944 70 0.186
Human Mouse
secretion by cell GO:0032940 248 0.183
Rat
single organism biosynthetic process GO:0044711 342 0.176
taxis GO:0042330 67 0.175
Human
negative regulation of apoptotic process GO:0043066 181 0.172
Human
regulation of cell motility GO:2000145 131 0.172
secretion GO:0046903 307 0.170
Rat
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.170
response to peptide hormone GO:0043434 278 0.168
regulation of rna metabolic process GO:0051252 391 0.165
regulation of nervous system development GO:0051960 264 0.164
Rat
positive regulation of biosynthetic process GO:0009891 319 0.163
regulation of transcription dna templated GO:0006355 374 0.163
response to external biotic stimulus GO:0043207 221 0.162
multi organism reproductive process GO:0044703 262 0.158
response to organophosphorus GO:0046683 102 0.149
positive regulation of developmental process GO:0051094 283 0.149
Human Mouse Rat
regulation of system process GO:0044057 208 0.148
positive regulation of programmed cell death GO:0043068 157 0.148
neuron projection development GO:0031175 273 0.147
Rat
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.145
cellular response to iron iii ion GO:0071283 3 0.144
regulation of cell migration GO:0030334 128 0.143
positive regulation of gene expression GO:0010628 244 0.142
sexual reproduction GO:0019953 148 0.142
regulation of catalytic activity GO:0050790 304 0.139
ossification GO:0001503 70 0.138
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.136
biological adhesion GO:0022610 110 0.135
Human Rat
cell adhesion GO:0007155 110 0.134
Human Rat
blood circulation GO:0008015 183 0.134
organ regeneration GO:0031100 101 0.133
positive regulation of cellular biosynthetic process GO:0031328 295 0.133
multicellular organismal reproductive process GO:0048609 233 0.133
positive regulation of phosphorylation GO:0042327 177 0.131
positive regulation of cellular component organization GO:0051130 200 0.131
regulation of cell cycle GO:0051726 73 0.130
cellular metal ion homeostasis GO:0006875 172 0.129
aging GO:0007568 241 0.128
Human
positive regulation of leukocyte migration GO:0002687 21 0.128
Human
epithelial cell proliferation GO:0050673 54 0.127
negative regulation of multicellular organismal process GO:0051241 203 0.127
Human Mouse Rat
response to nutrient GO:0007584 248 0.126
negative regulation of gene expression GO:0010629 199 0.125
regulation of neurogenesis GO:0050767 247 0.124
Rat
osteoblast differentiation GO:0001649 26 0.120
macromolecular complex subunit organization GO:0043933 339 0.119
cellular response to lipopolysaccharide GO:0071222 55 0.119
Human
neuron differentiation GO:0030182 368 0.119
Rat
regulation of cell projection organization GO:0031344 175 0.118
Rat
homeostatic process GO:0042592 331 0.118
cardiovascular system development GO:0072358 134 0.116
Human Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.115
regulation of intracellular signal transduction GO:1902531 218 0.114
positive regulation of neuron differentiation GO:0045666 126 0.113
Rat
rna metabolic process GO:0016070 406 0.113
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.113
regulation of osteoblast differentiation GO:0045667 14 0.112
response to tumor cell GO:0002347 4 0.112
cellular response to growth factor stimulus GO:0071363 162 0.110
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.110
regulation of rna biosynthetic process GO:2001141 381 0.108
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.108
gamete generation GO:0007276 124 0.107
cellular response to fluid shear stress GO:0071498 4 0.106
embryo implantation GO:0007566 15 0.105
Rat
regulation of kinase activity GO:0043549 117 0.104
response to carbohydrate GO:0009743 183 0.103
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.103
cellular response to ketone GO:1901655 51 0.103
response to glucocorticoid GO:0051384 223 0.103
response to hydrogen peroxide GO:0042542 89 0.101
circulatory system process GO:0003013 183 0.100
regulation of neuron differentiation GO:0045664 208 0.100
Rat
regulation of ossification GO:0030278 32 0.099
cellular response to molecule of bacterial origin GO:0071219 56 0.096
Human
cell cell signaling GO:0007267 335 0.096
negative regulation of signaling GO:0023057 157 0.095
Human
positive regulation of muscle contraction GO:0045933 22 0.095
growth GO:0040007 165 0.092
immune response GO:0006955 104 0.092
response to low density lipoprotein particle GO:0055098 4 0.092
positive regulation of nervous system development GO:0051962 178 0.091
Rat
cell projection organization GO:0030030 302 0.091
Rat
positive regulation of signal transduction GO:0009967 175 0.090
positive regulation of catalytic activity GO:0043085 184 0.088
smooth muscle cell migration GO:0014909 36 0.088
Human
positive regulation of leukocyte chemotaxis GO:0002690 10 0.088
Human
response to toxic substance GO:0009636 133 0.088
hindlimb morphogenesis GO:0035137 2 0.086
lipid metabolic process GO:0006629 283 0.086
cellular component morphogenesis GO:0032989 155 0.086
cell growth GO:0016049 104 0.085
regulation of cell adhesion GO:0030155 52 0.084
Human Rat
cellular response to platelet derived growth factor stimulus GO:0036120 7 0.084
cellular component assembly GO:0022607 360 0.083
positive regulation of angiogenesis GO:0045766 28 0.083
Human Mouse
regulation of phosphorylation GO:0042325 248 0.083
developmental growth GO:0048589 100 0.083
regulation of nf kappab import into nucleus GO:0042345 5 0.083
regulation of transferase activity GO:0051338 123 0.083
response to fatty acid GO:0070542 65 0.082
formation of primary germ layer GO:0001704 1 0.082
response to purine containing compound GO:0014074 126 0.082
granulocyte chemotaxis GO:0071621 15 0.082
positive regulation of phosphate metabolic process GO:0045937 262 0.081
response to ketone GO:1901654 182 0.081
fever generation GO:0001660 9 0.081
organic substance catabolic process GO:1901575 316 0.081
Rat
response to mineralocorticoid GO:0051385 49 0.081
limb morphogenesis GO:0035108 4 0.080
protein complex assembly GO:0006461 263 0.080
regulation of smooth muscle cell migration GO:0014910 36 0.080
Human
regulation of molecular function GO:0065009 398 0.079
cell cycle GO:0007049 101 0.078
immune system process GO:0002376 204 0.078
positive regulation of keratinocyte migration GO:0051549 2 0.078
neuron death GO:0070997 127 0.077
muscle contraction GO:0006936 88 0.077
cation transport GO:0006812 382 0.077
positive regulation of response to external stimulus GO:0032103 51 0.077
Human
negative regulation of cell differentiation GO:0045596 99 0.077
rhythmic process GO:0048511 156 0.077
single organism catabolic process GO:0044712 283 0.076
cellular response to peptide GO:1901653 133 0.076
positive regulation of intracellular signal transduction GO:1902533 138 0.076
cellular response to peptide hormone stimulus GO:0071375 120 0.075
positive regulation of nucleic acid templated transcription GO:1903508 197 0.075
regulation of behavior GO:0050795 61 0.075
Human
regulation of neuron projection development GO:0010975 161 0.075
Rat
cellular calcium ion homeostasis GO:0006874 160 0.074
neutrophil migration GO:1990266 12 0.074
embryonic hindlimb morphogenesis GO:0035116 2 0.074
skeletal muscle tissue regeneration GO:0043403 10 0.073
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.073
reactive oxygen species metabolic process GO:0072593 37 0.072
negative regulation of cell communication GO:0010648 158 0.072
Human
positive regulation of transcription dna templated GO:0045893 197 0.072
response to activity GO:0014823 73 0.072
regulation of synaptic transmission GO:0050804 141 0.071
response to metal ion GO:0010038 253 0.071
mapk cascade GO:0000165 140 0.070
response to ionizing radiation GO:0010212 59 0.069
regulation of vasculature development GO:1901342 44 0.068
Human Mouse
establishment of synaptic specificity at neuromuscular junction GO:0007529 1 0.068
negative regulation of metabolic process GO:0009892 331 0.067
response to amphetamine GO:0001975 25 0.067
positive regulation of molecular function GO:0044093 230 0.066
regulation of muscle system process GO:0090257 79 0.065
response to reactive oxygen species GO:0000302 120 0.064
carboxylic acid metabolic process GO:0019752 289 0.064
central nervous system development GO:0007417 311 0.064
protein phosphorylation GO:0006468 345 0.064
positive regulation of cell development GO:0010720 176 0.064
Rat
axon development GO:0061564 96 0.063
regulation of response to stress GO:0080134 126 0.063
Human Mouse Rat
response to hexose GO:0009746 144 0.063
regulation of protein transport GO:0051223 68 0.063
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.063
reproductive system development GO:0061458 128 0.062
signal transduction by phosphorylation GO:0023014 144 0.062
protein localization GO:0008104 191 0.061
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.060
regulation of secretion GO:0051046 224 0.060
single organism organelle organization GO:1902589 180 0.060
cellular response to steroid hormone stimulus GO:0071383 93 0.060
neurological system process GO:0050877 219 0.060
cellular chemical homeostasis GO:0055082 247 0.060
muscle system process GO:0003012 115 0.060
eosinophil chemotaxis GO:0048245 3 0.059
cellular response to tumor necrosis factor GO:0071356 46 0.059
cellular response to lipid GO:0071396 201 0.058
rna biosynthetic process GO:0032774 380 0.058
positive regulation of protein phosphorylation GO:0001934 135 0.058
regulation of secretion by cell GO:1903530 208 0.058
positive regulation of apoptotic process GO:0043065 154 0.058
neuron development GO:0048666 286 0.058
Rat
regulation of blood circulation GO:1903522 110 0.057
positive regulation of rna biosynthetic process GO:1902680 197 0.057
organic acid metabolic process GO:0006082 292 0.057
synaptic transmission GO:0007268 235 0.056
establishment of protein localization GO:0045184 141 0.056
female pregnancy GO:0007565 122 0.056
regulation of protein phosphorylation GO:0001932 183 0.055
t helper 1 type immune response GO:0042088 1 0.055
bmp signaling pathway GO:0030509 4 0.055
anatomical structure formation involved in morphogenesis GO:0048646 83 0.055
Human Mouse
positive regulation of transcription factor import into nucleus GO:0042993 4 0.055
angiogenesis GO:0001525 53 0.055
Human Mouse
female gonad development GO:0008585 53 0.055
positive regulation of transport GO:0051050 245 0.055
granulocyte migration GO:0097530 16 0.054
leukocyte mediated immunity GO:0002443 28 0.054
regulation of protein kinase activity GO:0045859 105 0.054
regulation of multicellular organismal development GO:2000026 376 0.054
Human Mouse Rat
positive regulation of neurogenesis GO:0050769 165 0.054
Rat
response to axon injury GO:0048678 59 0.053
developmental process involved in reproduction GO:0003006 159 0.053
hexose metabolic process GO:0019318 58 0.053
keratinocyte migration GO:0051546 2 0.052
interleukin 1 alpha biosynthetic process GO:0050719 1 0.052
regulation of immune response to tumor cell GO:0002837 3 0.051
chemical homeostasis GO:0048878 292 0.051
positive regulation of immune system process GO:0002684 90 0.050
Human
lymphocyte migration GO:0072676 3 0.050
regulation of phosphate metabolic process GO:0019220 349 0.049
positive regulation of cell death GO:0010942 184 0.049
ovulation cycle GO:0042698 67 0.049
cell matrix adhesion GO:0007160 19 0.049
Human
negative regulation of immune response to tumor cell GO:0002838 2 0.049
neutrophil chemotaxis GO:0030593 11 0.048
positive regulation of cell projection organization GO:0031346 111 0.048
Rat
regulation of smooth muscle contraction GO:0006940 29 0.048
negative regulation of macromolecule metabolic process GO:0010605 260 0.048
regulation of phosphorus metabolic process GO:0051174 349 0.047
regulation of t cell chemotaxis GO:0010819 1 0.047
positive regulation of cell differentiation GO:0045597 217 0.047
Rat
positive regulation of behavior GO:0048520 38 0.047
Human
protein transport GO:0015031 132 0.047
regulation of neuron death GO:1901214 115 0.047
positive regulation of rna metabolic process GO:0051254 203 0.047
response to insulin GO:0032868 133 0.047
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.047
defense response GO:0006952 194 0.047
Human Mouse
acute inflammatory response GO:0002526 58 0.047
regulation of tube size GO:0035150 89 0.046
cellular catabolic process GO:0044248 295 0.046
cellular response to organonitrogen compound GO:0071417 197 0.046
response to growth factor GO:0070848 189 0.046
cell morphogenesis GO:0000902 142 0.046
myeloid leukocyte migration GO:0097529 20 0.046
Human
regulation of muscle contraction GO:0006937 53 0.046
regulation of leukocyte mediated immunity GO:0002703 19 0.046
regulation of cell development GO:0060284 263 0.046
Rat
jak stat cascade GO:0007259 26 0.045
neuron projection regeneration GO:0031102 35 0.045
negative regulation of transport GO:0051051 136 0.044
heat acclimation GO:0010286 1 0.044
cytokine production GO:0001816 61 0.044
Human
cellular homeostasis GO:0019725 252 0.044
innate immune response GO:0045087 35 0.044
regulation of cellular localization GO:0060341 263 0.043
leukocyte cell cell adhesion GO:0007159 4 0.043
positive regulation of protein modification process GO:0031401 142 0.043
head development GO:0060322 247 0.043
positive regulation of lymphocyte migration GO:2000403 1 0.042
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.042
metal ion homeostasis GO:0055065 186 0.041
intracellular signal transduction GO:0035556 314 0.041
amine metabolic process GO:0009308 38 0.041
regulation of metanephros development GO:0072215 4 0.041
gastrulation GO:0007369 2 0.041
cellular response to external stimulus GO:0071496 118 0.041
positive regulation of secretion GO:0051047 140 0.040
cellular ion homeostasis GO:0006873 184 0.040
blood vessel morphogenesis GO:0048514 58 0.040
Human Mouse
regulation of lymphocyte migration GO:2000401 1 0.040
response to glucose GO:0009749 136 0.040
negative regulation of rna metabolic process GO:0051253 123 0.039
positive regulation of kinase activity GO:0033674 77 0.039
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.039
regulation of protein metabolic process GO:0051246 289 0.039
prostate gland epithelium morphogenesis GO:0060740 2 0.039
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.039
protein complex biogenesis GO:0070271 263 0.039
organonitrogen compound catabolic process GO:1901565 179 0.038
single organism intracellular transport GO:1902582 166 0.038
single organism cell adhesion GO:0098602 46 0.038
negative regulation of developmental process GO:0051093 125 0.038
Human Mouse
interleukin 1 biosynthetic process GO:0042222 1 0.038
chemotaxis GO:0006935 66 0.038
Human
cellular response to extracellular stimulus GO:0031668 73 0.038
negative regulation of transcription dna templated GO:0045892 116 0.037
calcium ion homeostasis GO:0055074 162 0.037
organonitrogen compound biosynthetic process GO:1901566 167 0.037
response to gamma radiation GO:0010332 24 0.037
cell substrate adhesion GO:0031589 29 0.036
Human
skeletal muscle tissue development GO:0007519 31 0.036
brain renin angiotensin system GO:0002035 3 0.036
ribonucleotide metabolic process GO:0009259 231 0.036
regulation of anatomical structure morphogenesis GO:0022603 141 0.036
Human Mouse
organic acid biosynthetic process GO:0016053 83 0.035
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.035
cellular cation homeostasis GO:0030003 180 0.035
cation homeostasis GO:0055080 195 0.035
regulation of t cell migration GO:2000404 1 0.035
epithelial cell migration GO:0010631 19 0.035
epithelial cell differentiation involved in prostate gland development GO:0060742 1 0.035
positive regulation of protein transport GO:0051222 41 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.034
cytokine mediated signaling pathway GO:0019221 43 0.034
regulation of neuron apoptotic process GO:0043523 83 0.034
multicellular organismal catabolic process GO:0044243 2 0.034
female sex differentiation GO:0046660 59 0.034
negative regulation of secretion by cell GO:1903531 72 0.034
negative regulation of biosynthetic process GO:0009890 168 0.034
regulation of protein localization GO:0032880 81 0.034
positive regulation of nf kappab import into nucleus GO:0042346 2 0.033
regulation of protein secretion GO:0050708 28 0.033
response to transition metal nanoparticle GO:1990267 122 0.033
cyclic purine nucleotide metabolic process GO:0052652 62 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.033
vesicle mediated transport GO:0016192 181 0.033
brain development GO:0007420 247 0.033
negative regulation of osteoblast differentiation GO:0045668 2 0.033
regulation of cytokine production GO:0001817 56 0.033
Human
response to radiation GO:0009314 137 0.032
Rat
enzyme linked receptor protein signaling pathway GO:0007167 116 0.032
response to cold GO:0009409 29 0.032
muscle cell proliferation GO:0033002 84 0.032
positive regulation of blood circulation GO:1903524 65 0.032
cellular response to corticosteroid stimulus GO:0071384 69 0.032
positive regulation of synaptic transmission GO:0050806 62 0.031
regulation of blood vessel size GO:0050880 89 0.031
regulation of synaptic plasticity GO:0048167 70 0.031
interleukin 1 alpha production GO:0032610 1 0.031
ion homeostasis GO:0050801 212 0.031
response to muscle stretch GO:0035994 2 0.030
regulation of anatomical structure size GO:0090066 135 0.030
sex differentiation GO:0007548 113 0.030
regulation of wound healing GO:0061041 14 0.030
Human Mouse Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.030
muscle structure development GO:0061061 87 0.030
cellular response to biotic stimulus GO:0071216 59 0.030
Human
development of primary sexual characteristics GO:0045137 107 0.030
vascular endothelial growth factor receptor signaling pathway GO:0048010 8 0.030
small gtpase mediated signal transduction GO:0007264 36 0.030
heart contraction GO:0060047 57 0.030
response to hyperoxia GO:0055093 45 0.029
muscle organ development GO:0007517 50 0.029
regulation of defense response GO:0031347 68 0.029
Human
inflammatory response GO:0006954 150 0.029
Human
positive regulation of protein metabolic process GO:0051247 178 0.029
protein complex subunit organization GO:0071822 302 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.029
epiboly involved in wound healing GO:0090505 2 0.029
vasoconstriction GO:0042310 54 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.029
response to amine GO:0014075 46 0.028
response to progesterone GO:0032570 48 0.028
regulation of cell killing GO:0031341 12 0.028
positive regulation of homeostatic process GO:0032846 49 0.028
protein oligomerization GO:0051259 191 0.028
regulation of mast cell chemotaxis GO:0060753 1 0.028
interleukin 6 production GO:0032635 12 0.028
cellular amine metabolic process GO:0044106 38 0.028
macromolecule localization GO:0033036 252 0.028
response to oxidative stress GO:0006979 186 0.028
cellular response to insulin stimulus GO:0032869 81 0.027
regulation of response to wounding GO:1903034 69 0.027
Human Mouse Rat
response to vitamin d GO:0033280 34 0.027
regulation of homeostatic process GO:0032844 101 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.027
negative regulation of neuron death GO:1901215 69 0.027
reproductive structure development GO:0048608 128 0.027
transmission of nerve impulse GO:0019226 42 0.027
negative regulation of rna biosynthetic process GO:1902679 118 0.027
regulation of cell morphogenesis GO:0022604 77 0.027
ovulation cycle process GO:0022602 50 0.027
response to camp GO:0051591 91 0.027
skeletal muscle organ development GO:0060538 33 0.027
cytosolic calcium ion homeostasis GO:0051480 140 0.026
response to electrical stimulus GO:0051602 56 0.026
multicellular organismal macromolecule metabolic process GO:0044259 21 0.026
response to high light intensity GO:0009644 1 0.026
response to monosaccharide GO:0034284 159 0.026
intracellular transport GO:0046907 185 0.026
behavior GO:0007610 205 0.026
Human
positive regulation of cytoskeleton organization GO:0051495 26 0.026
cellular response to lipoprotein particle stimulus GO:0071402 5 0.026
positive regulation of transferase activity GO:0051347 81 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
cellular response to nutrient levels GO:0031669 60 0.025
positive regulation of cardiac muscle contraction GO:0060452 4 0.025
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.025
tissue remodeling GO:0048771 40 0.025
carboxylic acid biosynthetic process GO:0046394 83 0.025
regulation of neurological system process GO:0031644 43 0.025
chemokine mediated signaling pathway GO:0070098 5 0.025
axon regeneration GO:0031103 28 0.025
positive regulation of interleukin 1 alpha biosynthetic process GO:0050726 1 0.025
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
monosaccharide metabolic process GO:0005996 61 0.025
protein homooligomerization GO:0051260 91 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
positive regulation of organelle organization GO:0010638 48 0.024

Serpine1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.056
muscular disease DOID:0080000 0 0.056
heart disease DOID:114 0 0.056
cardiomyopathy DOID:0050700 0 0.056
dilated cardiomyopathy DOID:12930 0 0.056
disease of anatomical entity DOID:7 0 0.056
intrinsic cardiomyopathy DOID:0060036 0 0.056
cardiovascular system disease DOID:1287 0 0.056
musculoskeletal system disease DOID:17 0 0.056
muscle tissue disease DOID:66 0 0.056
nervous system disease DOID:863 0 0.036
disease of cellular proliferation DOID:14566 0 0.029