Rattus norvegicus

150 known processes

Serpine2

serine (or cysteine) peptidase inhibitor, clade E, member 2

(Aliases: Pn-1,PI-7,Gdnpn1,Spin4)

Serpine2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane repolarization GO:0086009 1 0.471
cellular component movement GO:0006928 248 0.392
Rat
cell motility GO:0048870 202 0.390
Rat
regulation of membrane repolarization GO:0060306 1 0.316
regulation of cellular component organization GO:0051128 368 0.307
negative regulation of cardiac muscle tissue development GO:0055026 3 0.305
glomerular filtration GO:0003094 10 0.285
regulation of cell proliferation GO:0042127 359 0.284
Mouse Rat
response to peptide hormone GO:0043434 278 0.276
Rat
response to biotic stimulus GO:0009607 226 0.271
Rat
regulation of protein metabolic process GO:0051246 289 0.242
negative regulation of heart growth GO:0061117 3 0.236
response to peptide GO:1901652 292 0.232
Rat
neuron differentiation GO:0030182 368 0.221
cellular component assembly GO:0022607 360 0.212
wound healing GO:0042060 122 0.207
cardiac conduction GO:0061337 2 0.201
appendage morphogenesis GO:0035107 4 0.201
carboxylic acid metabolic process GO:0019752 289 0.191
cell projection organization GO:0030030 302 0.184
response to molecule of bacterial origin GO:0002237 194 0.183
Rat
response to hydrogen peroxide GO:0042542 89 0.182
Rat
programmed cell death GO:0012501 392 0.182
regulation of molecular function GO:0065009 398 0.179
negative regulation of multicellular organismal process GO:0051241 203 0.177
secretion by cell GO:0032940 248 0.177
apoptotic process GO:0006915 381 0.177
response to oxidative stress GO:0006979 186 0.177
Rat
reproductive system development GO:0061458 128 0.175
Mouse Rat
response to wounding GO:0009611 254 0.172
regulation of protein modification process GO:0031399 194 0.170
developmental process involved in reproduction GO:0003006 159 0.167
Mouse Rat
homeostatic process GO:0042592 331 0.166
Rat
locomotion GO:0040011 237 0.166
Rat
regeneration GO:0031099 163 0.162
Rat
positive regulation of signaling GO:0023056 270 0.159
Mouse
single organism reproductive process GO:0044702 297 0.155
response to fluid shear stress GO:0034405 16 0.155
Rat
chemical homeostasis GO:0048878 292 0.154
Rat
regulation of programmed cell death GO:0043067 341 0.143
response to monosaccharide GO:0034284 159 0.142
Rat
cellular component biogenesis GO:0044085 368 0.141
negative regulation of organ growth GO:0046621 3 0.134
renal filtration GO:0097205 10 0.133
sex differentiation GO:0007548 113 0.132
Rat
positive regulation of cell communication GO:0010647 271 0.132
Mouse
reproductive process GO:0022414 372 0.131
nitrogen compound transport GO:0071705 229 0.131
regulation of phosphate metabolic process GO:0019220 349 0.130
embryonic appendage morphogenesis GO:0035113 4 0.130
negative regulation of response to stimulus GO:0048585 155 0.129
cellular response to oxygen containing compound GO:1901701 386 0.127
Rat
response to estrogen GO:0043627 232 0.127
Rat
regulation of cell migration GO:0030334 128 0.126
Rat
response to external biotic stimulus GO:0043207 221 0.126
Rat
response to inorganic substance GO:0010035 377 0.124
Rat
aging GO:0007568 241 0.123
multicellular organismal signaling GO:0035637 44 0.123
localization of cell GO:0051674 202 0.117
Rat
response to reactive oxygen species GO:0000302 120 0.115
Rat
response to other organism GO:0051707 220 0.115
Rat
positive regulation of behavioral fear response GO:2000987 3 0.115
secretion GO:0046903 307 0.115
response to ketone GO:1901654 182 0.115
Rat
single organism biosynthetic process GO:0044711 342 0.111
regulation of response to external stimulus GO:0032101 106 0.107
response to lipopolysaccharide GO:0032496 191 0.105
Rat
regulation of cellular component movement GO:0051270 150 0.105
Rat
positive regulation of developmental process GO:0051094 283 0.105
cation transport GO:0006812 382 0.104
Mouse Rat
ion transmembrane transport GO:0034220 365 0.104
Rat
regulation of signal transduction GO:0009966 318 0.103
Mouse
organelle organization GO:0006996 266 0.103
vesicle mediated transport GO:0016192 181 0.103
Rat
oxoacid metabolic process GO:0043436 290 0.102
cellular response to hormone stimulus GO:0032870 247 0.101
Rat
cell migration GO:0016477 197 0.100
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.099
negative regulation of response to external stimulus GO:0032102 37 0.099
response to corticosteroid GO:0031960 235 0.096
Rat
multi multicellular organism process GO:0044706 138 0.096
regulation of metal ion transport GO:0010959 118 0.095
Mouse Rat
positive regulation of protein metabolic process GO:0051247 178 0.095
positive regulation of secretion GO:0051047 140 0.094
regulation of blood pressure GO:0008217 83 0.094
reproduction GO:0000003 245 0.094
Mouse Rat
regulation of peptide transport GO:0090087 87 0.093
anion transport GO:0006820 178 0.092
response to insulin GO:0032868 133 0.090
Rat
chemotaxis GO:0006935 66 0.090
epithelium development GO:0060429 96 0.089
Mouse
response to glucocorticoid GO:0051384 223 0.088
Rat
organic acid metabolic process GO:0006082 292 0.088
regulation of calcium ion transport GO:0051924 77 0.087
Rat
regulation of multicellular organismal development GO:2000026 376 0.087
regulation of ion transport GO:0043269 245 0.087
Mouse Rat
immune system process GO:0002376 204 0.086
Rat
positive regulation of phosphorylation GO:0042327 177 0.086
regulation of intracellular signal transduction GO:1902531 218 0.085
Mouse
male sex differentiation GO:0046661 64 0.084
regulation of cell differentiation GO:0045595 320 0.083
tube development GO:0035295 89 0.082
metal ion transport GO:0030001 289 0.081
Mouse Rat
behavior GO:0007610 205 0.081
Mouse
cellular cation homeostasis GO:0030003 180 0.081
calcium ion transport GO:0006816 131 0.081
Rat
response to estradiol GO:0032355 164 0.080
regulation of protein phosphorylation GO:0001932 183 0.080
positive regulation of response to stimulus GO:0048584 285 0.079
negative regulation of wound healing GO:0061045 8 0.079
positive regulation of multicellular organismal process GO:0051240 387 0.078
positive regulation of catalytic activity GO:0043085 184 0.078
catabolic process GO:0009056 351 0.077
head development GO:0060322 247 0.077
Mouse
cellular ketone metabolic process GO:0042180 51 0.077
organic anion transport GO:0015711 132 0.077
macromolecular complex assembly GO:0065003 273 0.076
organic substance catabolic process GO:1901575 316 0.076
negative regulation of metabolic process GO:0009892 331 0.076
cellular amino acid metabolic process GO:0006520 107 0.076
heart morphogenesis GO:0003007 3 0.075
central nervous system development GO:0007417 311 0.074
Human Mouse
cellular response to organonitrogen compound GO:0071417 197 0.074
Rat
regulation of growth GO:0040008 105 0.074
Mouse
cell adhesion GO:0007155 110 0.073
Mouse Rat
positive regulation of signal transduction GO:0009967 175 0.073
regulation of secretion by cell GO:1903530 208 0.073
intracellular signal transduction GO:0035556 314 0.073
Mouse
multicellular organism reproduction GO:0032504 233 0.072
Mouse Rat
female pregnancy GO:0007565 122 0.071
vasomotion GO:1990029 1 0.071
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.071
response to hexose GO:0009746 144 0.071
Rat
cell communication by chemical coupling GO:0010643 2 0.071
regulation of hormone secretion GO:0046883 106 0.070
organophosphate metabolic process GO:0019637 370 0.070
positive regulation of cellular component organization GO:0051130 200 0.070
skeletal muscle tissue regeneration GO:0043403 10 0.069
regulation of neurogenesis GO:0050767 247 0.069
regulation of apoptotic process GO:0042981 335 0.069
monovalent inorganic cation transport GO:0015672 172 0.069
Mouse
regulation of hormone levels GO:0010817 187 0.069
negative regulation of gene expression GO:0010629 199 0.069
response to carbohydrate GO:0009743 183 0.068
Rat
regulation of secretion GO:0051046 224 0.068
regulation of cellular amine metabolic process GO:0033238 8 0.067
regulation of cellular localization GO:0060341 263 0.067
regulation of behavior GO:0050795 61 0.065
protein complex biogenesis GO:0070271 263 0.065
positive regulation of phosphate metabolic process GO:0045937 262 0.065
response to radiation GO:0009314 137 0.065
anatomical structure morphogenesis GO:0009653 298 0.065
Mouse
renal system process GO:0003014 40 0.064
limb morphogenesis GO:0035108 4 0.064
neurological system process GO:0050877 219 0.064
Mouse
regulation of homeostatic process GO:0032844 101 0.064
regulation of response to stress GO:0080134 126 0.063
negative regulation of response to wounding GO:1903035 23 0.063
blood vessel development GO:0001568 69 0.063
positive regulation of phosphorus metabolic process GO:0010562 262 0.062
regulation of protein kinase activity GO:0045859 105 0.062
action potential GO:0001508 54 0.062
negative regulation of developmental process GO:0051093 125 0.061
regulation of wound healing GO:0061041 14 0.060
neuron projection development GO:0031175 273 0.060
positive regulation of transport GO:0051050 245 0.060
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.060
macromolecular complex subunit organization GO:0043933 339 0.059
protein phosphorylation GO:0006468 345 0.059
regulation of membrane potential GO:0042391 110 0.059
cell projection morphogenesis GO:0048858 123 0.058
negative regulation of apoptotic process GO:0043066 181 0.058
embryonic limb morphogenesis GO:0030326 4 0.058
regulation of peptide secretion GO:0002791 82 0.058
circulatory system process GO:0003013 183 0.057
lipid metabolic process GO:0006629 283 0.057
regulation of glomerular filtration GO:0003093 9 0.057
regulation of system process GO:0044057 208 0.057
signal transduction by phosphorylation GO:0023014 144 0.057
cellular divalent inorganic cation homeostasis GO:0072503 162 0.057
response to decreased oxygen levels GO:0036293 237 0.056
Rat
transmembrane transport GO:0055085 412 0.056
Rat
protein complex assembly GO:0006461 263 0.056
taxis GO:0042330 67 0.056
tissue remodeling GO:0048771 40 0.056
lipid biosynthetic process GO:0008610 128 0.056
small molecule biosynthetic process GO:0044283 124 0.056
positive regulation of intracellular signal transduction GO:1902533 138 0.056
response to bacterium GO:0009617 200 0.056
Rat
regulation of hydrolase activity GO:0051336 143 0.056
multicellular organismal reproductive process GO:0048609 233 0.056
Mouse Rat
positive regulation of programmed cell death GO:0043068 157 0.055
amide transport GO:0042886 105 0.055
cellular homeostasis GO:0019725 252 0.054
Rat
cellular response to abiotic stimulus GO:0071214 85 0.054
Rat
tissue regeneration GO:0042246 36 0.053
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.053
regulation of cell development GO:0060284 263 0.053
response to extracellular stimulus GO:0009991 380 0.053
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.053
cardiovascular system development GO:0072358 134 0.053
cellular response to endogenous stimulus GO:0071495 377 0.052
Rat
protein oligomerization GO:0051259 191 0.052
regulation of defense response GO:0031347 68 0.052
cellular response to oxidative stress GO:0034599 76 0.052
Rat
mapk cascade GO:0000165 140 0.052
cell cell signaling GO:0007267 335 0.051
Mouse
positive regulation of peptide secretion GO:0002793 52 0.051
defense response GO:0006952 194 0.051
cellular response to nitrogen compound GO:1901699 210 0.051
Rat
blood circulation GO:0008015 183 0.051
response to nutrient levels GO:0031667 370 0.051
Rat
cell part morphogenesis GO:0032990 123 0.050
dna metabolic process GO:0006259 96 0.050
negative regulation of cell death GO:0060548 229 0.050
cation homeostasis GO:0055080 195 0.050
regulation of peptide hormone secretion GO:0090276 80 0.050
cellular response to organic cyclic compound GO:0071407 202 0.049
Rat
neuron development GO:0048666 286 0.049
development of primary female sexual characteristics GO:0046545 56 0.049
Rat
peptide secretion GO:0002790 86 0.049
blood vessel morphogenesis GO:0048514 58 0.049
regulation of anatomical structure size GO:0090066 135 0.048
protein complex subunit organization GO:0071822 302 0.048
glucose homeostasis GO:0042593 75 0.048
Rat
cellular response to external stimulus GO:0071496 118 0.048
Rat
regulation of response to wounding GO:1903034 69 0.048
cellular ion homeostasis GO:0006873 184 0.048
regulation of cell motility GO:2000145 131 0.048
Rat
rhythmic process GO:0048511 156 0.047
negative regulation of programmed cell death GO:0043069 183 0.047
sensory organ development GO:0007423 74 0.047
response to nutrient GO:0007584 248 0.047
cellular amine metabolic process GO:0044106 38 0.047
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.047
camera type eye development GO:0043010 48 0.047
embryonic organ morphogenesis GO:0048562 5 0.046
peptide transport GO:0015833 97 0.046
striated muscle tissue development GO:0014706 58 0.046
hormone secretion GO:0046879 115 0.046
metal ion homeostasis GO:0055065 186 0.046
multi organism reproductive process GO:0044703 262 0.045
growth GO:0040007 165 0.045
Mouse Rat
cellular response to stress GO:0033554 269 0.045
Rat
inflammatory response GO:0006954 150 0.044
actin filament based process GO:0030029 86 0.044
negative regulation of cardiac muscle cell proliferation GO:0060044 2 0.044
amine metabolic process GO:0009308 38 0.044
calcium ion homeostasis GO:0055074 162 0.044
cardiac muscle cell proliferation GO:0060038 6 0.044
regulation of catalytic activity GO:0050790 304 0.044
muscle cell proliferation GO:0033002 84 0.043
positive regulation of secretion by cell GO:1903532 128 0.043
cell cycle GO:0007049 101 0.043
circulatory system development GO:0072359 134 0.043
regulation of cellular amino acid metabolic process GO:0006521 2 0.043
cellular metal ion homeostasis GO:0006875 172 0.042
cellular calcium ion homeostasis GO:0006874 160 0.042
neuronal action potential GO:0019228 35 0.042
positive regulation of molecular function GO:0044093 230 0.041
carbohydrate metabolic process GO:0005975 130 0.041
regulation of locomotion GO:0040012 148 0.041
Rat
positive regulation of apoptotic process GO:0043065 154 0.040
response to hypoxia GO:0001666 231 0.040
Rat
hormone transport GO:0009914 121 0.040
regulation of neuron differentiation GO:0045664 208 0.039
metanephric comma shaped body morphogenesis GO:0072278 2 0.039
organonitrogen compound biosynthetic process GO:1901566 167 0.039
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.039
carboxylic acid biosynthetic process GO:0046394 83 0.039
brain development GO:0007420 247 0.039
Mouse
myelination GO:0042552 39 0.038
negative regulation of macromolecule metabolic process GO:0010605 260 0.038
cellular component morphogenesis GO:0032989 155 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
regulation of nervous system development GO:0051960 264 0.038
placenta development GO:0001890 22 0.038
Rat
muscle structure development GO:0061061 87 0.037
response to metal ion GO:0010038 253 0.037
Rat
regulation of tight junction assembly GO:2000810 2 0.037
positive regulation of defense response GO:0031349 37 0.037
peptide hormone secretion GO:0030072 84 0.037
signal release GO:0023061 145 0.037
regulation of transferase activity GO:0051338 123 0.037
vasculature development GO:0001944 70 0.037
positive regulation of cell differentiation GO:0045597 217 0.037
regulation of phosphorylation GO:0042325 248 0.036
vascular process in circulatory system GO:0003018 96 0.036
cell morphogenesis GO:0000902 142 0.036
adenine nucleotide transport GO:0051503 2 0.036
cellular response to glucocorticoid stimulus GO:0071385 68 0.036
Rat
macromolecule localization GO:0033036 252 0.036
lens development in camera type eye GO:0002088 13 0.036
regulation of blood circulation GO:1903522 110 0.036
protein localization GO:0008104 191 0.036
developmental growth GO:0048589 100 0.035
Rat
glial cell differentiation GO:0010001 65 0.035
Human
ion homeostasis GO:0050801 212 0.035
response to electrical stimulus GO:0051602 56 0.035
enzyme linked receptor protein signaling pathway GO:0007167 116 0.035
positive regulation of cell proliferation GO:0008284 249 0.035
Rat
response to alkaloid GO:0043279 132 0.035
Rat
regulation of tube size GO:0035150 89 0.034
organ regeneration GO:0031100 101 0.034
protein transport GO:0015031 132 0.034
ensheathment of neurons GO:0007272 40 0.034
positive regulation of cellular protein metabolic process GO:0032270 167 0.034
cellular chemical homeostasis GO:0055082 247 0.034
Rat
response to acid chemical GO:0001101 222 0.034
negative regulation of protein metabolic process GO:0051248 114 0.033
regulation of kinase activity GO:0043549 117 0.033
divalent inorganic cation homeostasis GO:0072507 165 0.033
heart contraction GO:0060047 57 0.033
regulation of dna metabolic process GO:0051052 60 0.033
cytoskeleton organization GO:0007010 111 0.033
negative regulation of cellular protein metabolic process GO:0032269 106 0.033
negative regulation of signaling GO:0023057 157 0.033
Mouse
positive regulation of peptide hormone secretion GO:0090277 50 0.033
cell cell junction organization GO:0045216 20 0.033
single organism behavior GO:0044708 130 0.033
Mouse
positive regulation of behavior GO:0048520 38 0.033
regulation of blood vessel size GO:0050880 89 0.033
positive regulation of protein modification process GO:0031401 142 0.032
neuron apoptotic process GO:0051402 88 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
positive regulation of cellular amine metabolic process GO:0033240 3 0.032
positive regulation of protein phosphorylation GO:0001934 135 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
maternal process involved in female pregnancy GO:0060135 38 0.032
Rat
organic acid biosynthetic process GO:0016053 83 0.031
potassium ion transport GO:0006813 97 0.031
regulation of cellular component biogenesis GO:0044087 86 0.031
peptidyl tyrosine phosphorylation GO:0018108 72 0.031
regulation of mapk cascade GO:0043408 116 0.031
divalent inorganic cation transport GO:0072511 134 0.031
Rat
organophosphate biosynthetic process GO:0090407 143 0.030
neuron projection morphogenesis GO:0048812 122 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.030
regulation of immune system process GO:0002682 123 0.030
epithelial cell differentiation GO:0030855 71 0.030
regulation of cell projection organization GO:0031344 175 0.030
cell chemotaxis GO:0060326 31 0.030
multicellular organismal homeostasis GO:0048871 49 0.030
peptidyl tyrosine modification GO:0018212 72 0.029
positive regulation of hormone secretion GO:0046887 65 0.029
actin cytoskeleton organization GO:0030036 73 0.029
inorganic cation transmembrane transport GO:0098662 202 0.029
transmission of nerve impulse GO:0019226 42 0.029
negative regulation of neurogenesis GO:0050768 78 0.029
nucleotide metabolic process GO:0009117 279 0.028
regulation of neuron projection development GO:0010975 161 0.028
negative regulation of growth GO:0045926 37 0.028
Mouse
response to oxygen levels GO:0070482 265 0.028
Rat
response to organophosphorus GO:0046683 102 0.028
Rat
negative regulation of cell communication GO:0010648 158 0.028
Mouse
cellular catabolic process GO:0044248 295 0.028
insulin secretion GO:0030073 69 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.028
cell type specific apoptotic process GO:0097285 134 0.028
cell morphogenesis involved in differentiation GO:0000904 119 0.028
carbohydrate homeostasis GO:0033500 75 0.028
Rat
gonad development GO:0008406 104 0.027
Rat
rna metabolic process GO:0016070 406 0.027
female sex differentiation GO:0046660 59 0.027
Rat
small gtpase mediated signal transduction GO:0007264 36 0.027
negative regulation of molecular function GO:0044092 133 0.027
eye development GO:0001654 50 0.027
axon development GO:0061564 96 0.027
smooth muscle cell proliferation GO:0048659 77 0.027
sexual reproduction GO:0019953 148 0.027
Mouse
response to temperature stimulus GO:0009266 94 0.027
positive regulation of ion transport GO:0043270 94 0.027
Rat
positive regulation of neurogenesis GO:0050769 165 0.027
cytosolic calcium ion homeostasis GO:0051480 140 0.027
cellular response to corticosteroid stimulus GO:0071384 69 0.026
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.026
biological adhesion GO:0022610 110 0.026
Mouse Rat
positive regulation of cell communication by chemical coupling GO:0010652 2 0.026
transcription dna templated GO:0006351 377 0.026
reproductive structure development GO:0048608 128 0.026
Mouse Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.026
positive regulation of vasodilation GO:0045909 29 0.026
regulation of insulin secretion GO:0050796 65 0.026
regulation of transcription dna templated GO:0006355 374 0.026
ribonucleotide metabolic process GO:0009259 231 0.025
positive regulation of nervous system development GO:0051962 178 0.025
regulation of systemic arterial blood pressure GO:0003073 30 0.025
response to growth factor GO:0070848 189 0.025
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
positive regulation of hydrolase activity GO:0051345 86 0.025
anterior posterior pattern specification GO:0009952 1 0.025
regulation of nucleotide metabolic process GO:0006140 117 0.025
tube morphogenesis GO:0035239 23 0.024
tissue development GO:0009888 252 0.024
Mouse Rat
regulation of cardiac muscle tissue development GO:0055024 12 0.024
single organism carbohydrate metabolic process GO:0044723 118 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
response to mechanical stimulus GO:0009612 134 0.024
Mouse Rat
sensory perception GO:0007600 101 0.024
Mouse
cellular response to insulin stimulus GO:0032869 81 0.024
Rat
ras protein signal transduction GO:0007265 29 0.024
cellular lipid metabolic process GO:0044255 208 0.024
regulation of catabolic process GO:0009894 113 0.024
heart development GO:0007507 72 0.024
proteolysis GO:0006508 175 0.023
regulation of canonical wnt signaling pathway GO:0060828 4 0.023
spindle organization GO:0007051 2 0.023
response to axon injury GO:0048678 59 0.023
cellular response to mechanical stimulus GO:0071260 48 0.023
Rat
single organism cell adhesion GO:0098602 46 0.023
Mouse
forebrain development GO:0030900 98 0.023
response to light stimulus GO:0009416 52 0.023
positive regulation of cell motility GO:2000147 97 0.023
Rat
gliogenesis GO:0042063 93 0.023
Human
synapse organization GO:0050808 46 0.023
organ morphogenesis GO:0009887 75 0.023
regulation of body fluid levels GO:0050878 90 0.023
gland development GO:0048732 155 0.023
Mouse
positive regulation of cell migration GO:0030335 96 0.022
Rat
development of primary sexual characteristics GO:0045137 107 0.022
Rat
cation transmembrane transport GO:0098655 263 0.022
cell junction organization GO:0034330 21 0.022
axon ensheathment GO:0008366 40 0.022
synaptic transmission GO:0007268 235 0.022
Mouse
eye morphogenesis GO:0048592 4 0.022
mitotic cell cycle GO:0000278 49 0.022
muscle tissue development GO:0060537 58 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
gastrulation GO:0007369 2 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
single organismal cell cell adhesion GO:0016337 42 0.022
Mouse
ovulation cycle process GO:0022602 50 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
cellular response to hexose stimulus GO:0071331 65 0.021
Rat
response to glucose GO:0009749 136 0.021
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
ossification GO:0001503 70 0.021
s shaped body morphogenesis GO:0072050 2 0.021
heart process GO:0003015 57 0.021
mechanoreceptor differentiation GO:0042490 2 0.021
nucleic acid templated transcription GO:0097659 379 0.021
mesoderm development GO:0007498 2 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
reactive oxygen species metabolic process GO:0072593 37 0.021
single organism catabolic process GO:0044712 283 0.020
vasodilation GO:0042311 44 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
muscle system process GO:0003012 115 0.020
positive regulation of immune system process GO:0002684 90 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
response to transition metal nanoparticle GO:1990267 122 0.020
monosaccharide metabolic process GO:0005996 61 0.020
regulation of tissue remodeling GO:0034103 14 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
peptidyl amino acid modification GO:0018193 126 0.020
protein autophosphorylation GO:0046777 66 0.020
positive regulation of cellular component movement GO:0051272 102 0.019
Rat
ovulation cycle GO:0042698 67 0.019
axonogenesis GO:0007409 71 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
Rat
negative regulation of nervous system development GO:0051961 79 0.019
rna biosynthetic process GO:0032774 380 0.019
morphogenesis of an epithelium GO:0002009 20 0.019
monocarboxylic acid metabolic process GO:0032787 152 0.019
cellular response to lipid GO:0071396 201 0.019
Rat
motor neuron axon guidance GO:0008045 1 0.019
positive regulation of cell death GO:0010942 184 0.019
lymphoid progenitor cell differentiation GO:0002320 2 0.019
single organism organelle organization GO:1902589 180 0.019
neural crest cell development GO:0014032 2 0.019
regulation of neuron death GO:1901214 115 0.019
carboxylic acid transport GO:0046942 115 0.018
renal system development GO:0072001 67 0.018
cardiac muscle tissue growth GO:0055017 20 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
female gonad development GO:0008585 53 0.018
Rat
endothelial cell proliferation GO:0001935 20 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
positive regulation of protein kinase activity GO:0045860 73 0.018
tissue morphogenesis GO:0048729 22 0.018
vasculogenesis GO:0001570 3 0.018
response to purine containing compound GO:0014074 126 0.018
Rat
response to fatty acid GO:0070542 65 0.018
oxidation reduction process GO:0055114 304 0.018
response to ethanol GO:0045471 162 0.018
neuron death GO:0070997 127 0.018
epithelial cell proliferation GO:0050673 54 0.018
embryonic cranial skeleton morphogenesis GO:0048701 2 0.018
urogenital system development GO:0001655 78 0.018
multicellular organismal response to stress GO:0033555 25 0.018
fear response GO:0042596 9 0.018
regulation of striated muscle tissue development GO:0016202 25 0.017

Serpine2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.028
disease of anatomical entity DOID:7 0 0.028
organ system cancer DOID:0050686 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.018