Rattus norvegicus

62 known processes

Sftpb

surfactant protein B

(Aliases: Sp-b)

Sftpb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 365 0.282
cation transport GO:0006812 382 0.192
inorganic ion transmembrane transport GO:0098660 229 0.177
regulation of phosphorus metabolic process GO:0051174 349 0.168
circulatory system process GO:0003013 183 0.157
response to corticosteroid GO:0031960 235 0.154
rna metabolic process GO:0016070 406 0.147
nucleobase containing small molecule metabolic process GO:0055086 316 0.141
positive regulation of phosphorus metabolic process GO:0010562 262 0.126
reproductive process GO:0022414 372 0.113
positive regulation of transport GO:0051050 245 0.111
multicellular organism reproduction GO:0032504 233 0.110
regulation of molecular function GO:0065009 398 0.107
secretion by cell GO:0032940 248 0.106
regulation of rna metabolic process GO:0051252 391 0.104
carbohydrate derivative metabolic process GO:1901135 346 0.102
response to lipopolysaccharide GO:0032496 191 0.099
positive regulation of signaling GO:0023056 270 0.099
neuron development GO:0048666 286 0.097
negative regulation of metabolic process GO:0009892 331 0.096
calcium ion import GO:0070509 22 0.096
regulation of rna biosynthetic process GO:2001141 381 0.092
response to ketone GO:1901654 182 0.087
nucleoside phosphate metabolic process GO:0006753 283 0.084
regulation of cell proliferation GO:0042127 359 0.083
metal ion transport GO:0030001 289 0.080
ribose phosphate metabolic process GO:0019693 235 0.079
multi multicellular organism process GO:0044706 138 0.078
response to hexose GO:0009746 144 0.076
protein homooligomerization GO:0051260 91 0.075
protein complex biogenesis GO:0070271 263 0.075
response to vitamin GO:0033273 131 0.074
neuron death GO:0070997 127 0.072
response to oxygen levels GO:0070482 265 0.068
inorganic cation transmembrane transport GO:0098662 202 0.067
organophosphate metabolic process GO:0019637 370 0.067
cellular response to stress GO:0033554 269 0.066
transcription from rna polymerase ii promoter GO:0006366 252 0.065
positive regulation of phosphate metabolic process GO:0045937 262 0.063
lipid biosynthetic process GO:0008610 128 0.063
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.060
cell projection organization GO:0030030 302 0.060
positive regulation of multicellular organismal process GO:0051240 387 0.060
positive regulation of gene expression GO:0010628 244 0.059
nucleotide metabolic process GO:0009117 279 0.059
response to peptide hormone GO:0043434 278 0.059
purine nucleotide biosynthetic process GO:0006164 83 0.059
positive regulation of biosynthetic process GO:0009891 319 0.058
positive regulation of cellular biosynthetic process GO:0031328 295 0.058
intracellular transport GO:0046907 185 0.057
protein complex subunit organization GO:0071822 302 0.057
positive regulation of developmental process GO:0051094 283 0.057
behavior GO:0007610 205 0.056
transmembrane transport GO:0055085 412 0.056
single organism reproductive process GO:0044702 297 0.055
response to glucocorticoid GO:0051384 223 0.054
response to peptide GO:1901652 292 0.054
wound healing GO:0042060 122 0.053
nephric duct development GO:0072176 1 0.053
macromolecular complex assembly GO:0065003 273 0.052
rna biosynthetic process GO:0032774 380 0.052
reproduction GO:0000003 245 0.052
blood circulation GO:0008015 183 0.051
cellular response to organic cyclic compound GO:0071407 202 0.051
cyclic purine nucleotide metabolic process GO:0052652 62 0.050
positive regulation of catalytic activity GO:0043085 184 0.050
oxidation reduction process GO:0055114 304 0.049
chemical homeostasis GO:0048878 292 0.048
positive regulation of protein kinase activity GO:0045860 73 0.048
response to purine containing compound GO:0014074 126 0.048
multicellular organismal reproductive process GO:0048609 233 0.048
protein phosphorylation GO:0006468 345 0.047
positive regulation of protein metabolic process GO:0051247 178 0.046
secretion GO:0046903 307 0.046
g protein coupled receptor signaling pathway GO:0007186 242 0.046
tube development GO:0035295 89 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.045
positive regulation of rna biosynthetic process GO:1902680 197 0.044
response to glucose GO:0009749 136 0.044
multicellular organism growth GO:0035264 1 0.043
regulation of phosphate metabolic process GO:0019220 349 0.042
protein oligomerization GO:0051259 191 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.042
regulation of catalytic activity GO:0050790 304 0.042
muscle tissue development GO:0060537 58 0.042
cellular component biogenesis GO:0044085 368 0.042
regulation of programmed cell death GO:0043067 341 0.041
rhythmic process GO:0048511 156 0.041
response to nutrient GO:0007584 248 0.041
cellular response to endogenous stimulus GO:0071495 377 0.041
programmed cell death GO:0012501 392 0.041
positive regulation of molecular function GO:0044093 230 0.040
regulation of apoptotic process GO:0042981 335 0.040
positive regulation of programmed cell death GO:0043068 157 0.040
response to carbohydrate GO:0009743 183 0.039
response to reactive oxygen species GO:0000302 120 0.039
neuron differentiation GO:0030182 368 0.039
organophosphate biosynthetic process GO:0090407 143 0.039
positive regulation of cell communication GO:0010647 271 0.038
response to extracellular stimulus GO:0009991 380 0.038
digestive tract development GO:0048565 39 0.038
negative regulation of response to stimulus GO:0048585 155 0.038
carbohydrate homeostasis GO:0033500 75 0.038
apoptotic process GO:0006915 381 0.038
regulation of metal ion transport GO:0010959 118 0.038
cellular response to hormone stimulus GO:0032870 247 0.038
response to hypoxia GO:0001666 231 0.038
regeneration GO:0031099 163 0.038
regulation of body fluid levels GO:0050878 90 0.037
multi organism reproductive process GO:0044703 262 0.037
regulation of growth GO:0040008 105 0.036
response to molecule of bacterial origin GO:0002237 194 0.036
negative regulation of biosynthetic process GO:0009890 168 0.036
sexual reproduction GO:0019953 148 0.035
response to camp GO:0051591 91 0.035
response to organophosphorus GO:0046683 102 0.035
sodium ion transport GO:0006814 82 0.035
negative regulation of nucleic acid templated transcription GO:1903507 117 0.035
cellular response to oxidative stress GO:0034599 76 0.034
response to nutrient levels GO:0031667 370 0.034
epithelium development GO:0060429 96 0.034
response to cytokine GO:0034097 215 0.034
regulation of system process GO:0044057 208 0.034
regulation of cellular component organization GO:0051128 368 0.034
ribonucleotide biosynthetic process GO:0009260 85 0.034
response to acid chemical GO:0001101 222 0.033
purine nucleotide metabolic process GO:0006163 229 0.033
regulation of cell development GO:0060284 263 0.033
homeostatic process GO:0042592 331 0.033
positive regulation of kinase activity GO:0033674 77 0.033
purine ribonucleotide metabolic process GO:0009150 227 0.033
negative regulation of gene expression GO:0010629 199 0.033
regulation of cellular component movement GO:0051270 150 0.033
development of primary female sexual characteristics GO:0046545 56 0.032
cyclic nucleotide metabolic process GO:0009187 80 0.032
regulation of cell differentiation GO:0045595 320 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
negative regulation of transcription dna templated GO:0045892 116 0.032
hexose metabolic process GO:0019318 58 0.032
central nervous system development GO:0007417 311 0.031
cation homeostasis GO:0055080 195 0.031
negative regulation of rna biosynthetic process GO:1902679 118 0.031
positive regulation of protein modification process GO:0031401 142 0.031
divalent inorganic cation transport GO:0072511 134 0.030
response to estrogen GO:0043627 232 0.030
developmental process involved in reproduction GO:0003006 159 0.030
circulatory system development GO:0072359 134 0.030
regulation of cell projection organization GO:0031344 175 0.030
single organism biosynthetic process GO:0044711 342 0.030
aging GO:0007568 241 0.030
maternal aggressive behavior GO:0002125 3 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
ribonucleotide metabolic process GO:0009259 231 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
regulation of nervous system development GO:0051960 264 0.029
divalent metal ion transport GO:0070838 132 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.029
purine containing compound biosynthetic process GO:0072522 85 0.029
regulation of kinase activity GO:0043549 117 0.029
response to estradiol GO:0032355 164 0.028
calcium ion transport GO:0006816 131 0.028
vesicle mediated transport GO:0016192 181 0.028
reproductive system development GO:0061458 128 0.028
cellular response to acid chemical GO:0071229 75 0.028
organic substance catabolic process GO:1901575 316 0.028
lipid localization GO:0010876 62 0.027
nucleic acid templated transcription GO:0097659 379 0.027
regulation of transcription dna templated GO:0006355 374 0.027
purine containing compound metabolic process GO:0072521 253 0.027
cellular ketone metabolic process GO:0042180 51 0.027
regulation of cellular catabolic process GO:0031329 101 0.026
positive regulation of transferase activity GO:0051347 81 0.026
ribose phosphate biosynthetic process GO:0046390 87 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
negative regulation of rna metabolic process GO:0051253 123 0.026
calcium ion homeostasis GO:0055074 162 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
nucleoside phosphate biosynthetic process GO:1901293 102 0.025
regulation of lipid biosynthetic process GO:0046890 38 0.025
positive regulation of ion transport GO:0043270 94 0.025
gamete generation GO:0007276 124 0.025
regulation of protein phosphorylation GO:0001932 183 0.025
single organism behavior GO:0044708 130 0.025
transcription dna templated GO:0006351 377 0.025
cation transmembrane transport GO:0098655 263 0.024
response to retinoic acid GO:0032526 63 0.024
positive regulation of transcription dna templated GO:0045893 197 0.023
macromolecule localization GO:0033036 252 0.023
carbohydrate derivative biosynthetic process GO:1901137 124 0.023
gastrulation GO:0007369 2 0.023
regulation of ion transmembrane transport GO:0034765 121 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
synaptic transmission GO:0007268 235 0.023
regulation of protein modification process GO:0031399 194 0.023
protein complex assembly GO:0006461 263 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
single organism cellular localization GO:1902580 102 0.023
calcium ion transmembrane transport GO:0070588 70 0.022
brain development GO:0007420 247 0.022
hormone biosynthetic process GO:0042446 25 0.022
reproductive structure development GO:0048608 128 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.022
divalent inorganic cation homeostasis GO:0072507 165 0.022
regulation of anatomical structure size GO:0090066 135 0.022
metanephric comma shaped body morphogenesis GO:0072278 2 0.022
regulation of protein kinase activity GO:0045859 105 0.022
response to wounding GO:0009611 254 0.022
positive regulation of cell development GO:0010720 176 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
glucose homeostasis GO:0042593 75 0.021
positive regulation of cell death GO:0010942 184 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
neurological system process GO:0050877 219 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
regulation of cellular localization GO:0060341 263 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
protein localization GO:0008104 191 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
s shaped body morphogenesis GO:0072050 2 0.020
response to fatty acid GO:0070542 65 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.020
positive regulation of secretion GO:0051047 140 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
cell type specific apoptotic process GO:0097285 134 0.020
cellular chemical homeostasis GO:0055082 247 0.020
single organism intracellular transport GO:1902582 166 0.020
cellular component assembly GO:0022607 360 0.020
response to hyperoxia GO:0055093 45 0.020
metanephric s shaped body morphogenesis GO:0072284 2 0.020
retina morphogenesis in camera type eye GO:0060042 1 0.020
response to monosaccharide GO:0034284 159 0.019
growth GO:0040007 165 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
thyroid gland development GO:0030878 1 0.019
response to oxidative stress GO:0006979 186 0.019
purine ribonucleotide biosynthetic process GO:0009152 81 0.019
response to external biotic stimulus GO:0043207 221 0.019
ion homeostasis GO:0050801 212 0.019
proteolysis GO:0006508 175 0.019
head development GO:0060322 247 0.019
cellular catabolic process GO:0044248 295 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
response to insulin GO:0032868 133 0.018
regulation of secretion GO:0051046 224 0.018
nucleotide biosynthetic process GO:0009165 98 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
gland development GO:0048732 155 0.018
regulation of neuron projection development GO:0010975 161 0.018
regulation of blood pressure GO:0008217 83 0.018
tissue development GO:0009888 252 0.018
adenohypophysis development GO:0021984 2 0.018
response to vitamin a GO:0033189 36 0.018
cell cell signaling GO:0007267 335 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
axis specification GO:0009798 4 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
regulation of phosphorylation GO:0042325 248 0.017
regulation of neurogenesis GO:0050767 247 0.017
regulation of calcium ion transport GO:0051924 77 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.017
organ morphogenesis GO:0009887 75 0.017
transmission of nerve impulse GO:0019226 42 0.017
regulation of locomotion GO:0040012 148 0.017
regulation of ion transmembrane transporter activity GO:0032412 48 0.017
salivary gland development GO:0007431 3 0.017
female gonad development GO:0008585 53 0.017
sex differentiation GO:0007548 113 0.017
regulation of signal transduction GO:0009966 318 0.017
female sex differentiation GO:0046660 59 0.016
negative regulation of cell death GO:0060548 229 0.016
steroid biosynthetic process GO:0006694 48 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
endocrine system development GO:0035270 30 0.016
nuclear transport GO:0051169 49 0.016
mesoderm development GO:0007498 2 0.016
cardiovascular system development GO:0072358 134 0.016
synaptic transmission glutamatergic GO:0035249 33 0.016
neuron projection development GO:0031175 273 0.016
spermatogenesis GO:0007283 99 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
positive regulation of peptide secretion GO:0002793 52 0.016
regulation of transferase activity GO:0051338 123 0.016
cellular response to drug GO:0035690 30 0.016
peptide hormone secretion GO:0030072 84 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
cyclic nucleotide biosynthetic process GO:0009190 63 0.016
amine metabolic process GO:0009308 38 0.015
embryonic pattern specification GO:0009880 1 0.015
tongue morphogenesis GO:0043587 3 0.015
carbohydrate metabolic process GO:0005975 130 0.015
establishment of protein localization GO:0045184 141 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
cellular amine metabolic process GO:0044106 38 0.015
regulation of blood vessel size GO:0050880 89 0.015
negative regulation of neuron death GO:1901215 69 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
vascular process in circulatory system GO:0003018 96 0.015
ovulation cycle GO:0042698 67 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
regulation of membrane potential GO:0042391 110 0.014
regulation of neuron death GO:1901214 115 0.014
protein heterooligomerization GO:0051291 89 0.014
regulation of reactive oxygen species metabolic process GO:2000377 26 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
response to inorganic substance GO:0010035 377 0.014
protein targeting GO:0006605 61 0.014
regulation of cell migration GO:0030334 128 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.014
cellular cation homeostasis GO:0030003 180 0.014
locomotory exploration behavior GO:0035641 1 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
intracellular signal transduction GO:0035556 314 0.014
porphyrin containing compound metabolic process GO:0006778 8 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
negative regulation of molecular function GO:0044092 133 0.013
cellular homeostasis GO:0019725 252 0.013
regulation of ion transport GO:0043269 245 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
regulation of transmembrane transporter activity GO:0022898 49 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.013
negative regulation of calcium ion import GO:0090281 2 0.013
regulation of cell cycle GO:0051726 73 0.013
circadian rhythm GO:0007623 88 0.013
negative regulation of signaling GO:0023057 157 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
forebrain development GO:0030900 98 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
potassium ion transport GO:0006813 97 0.012
regulation of transmembrane transport GO:0034762 122 0.012
positive regulation of potassium ion transmembrane transport GO:1901381 4 0.012
cellular response to lipid GO:0071396 201 0.012
regulation of carbohydrate metabolic process GO:0006109 41 0.012
heart morphogenesis GO:0003007 3 0.012
cellular response to external stimulus GO:0071496 118 0.012
response to metal ion GO:0010038 253 0.012
cell growth GO:0016049 104 0.012
multicellular organismal signaling GO:0035637 44 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
muscle structure development GO:0061061 87 0.012
male gamete generation GO:0048232 99 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
behavioral response to ethanol GO:0048149 1 0.012
regulation of metanephros development GO:0072215 4 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of vascular smooth muscle contraction GO:0003056 3 0.012
grooming behavior GO:0007625 4 0.012
cellular response to carbohydrate stimulus GO:0071322 72 0.012
positive regulation of map kinase activity GO:0043406 46 0.012
muscle contraction GO:0006936 88 0.011
mesoderm morphogenesis GO:0048332 1 0.011
response to decreased oxygen levels GO:0036293 237 0.011
visual perception GO:0007601 3 0.011
cell activation GO:0001775 97 0.011
regulation of protein maturation GO:1903317 50 0.011
positive regulation of lipid biosynthetic process GO:0046889 25 0.011
nucleoside catabolic process GO:0009164 126 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
metal ion homeostasis GO:0055065 186 0.011
adaptation of signaling pathway GO:0023058 10 0.011
cytoplasmic transport GO:0016482 115 0.011
camp metabolic process GO:0046058 63 0.011
anterior posterior pattern specification GO:0009952 1 0.011
cellular response to histamine GO:0071420 3 0.011
regulation of cellular response to stress GO:0080135 49 0.011
development of primary sexual characteristics GO:0045137 107 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
embryonic axis specification GO:0000578 1 0.011
regulation of cell growth GO:0001558 85 0.011
formation of primary germ layer GO:0001704 1 0.011
mesoderm formation GO:0001707 1 0.011
carboxylic acid transport GO:0046942 115 0.011
response to ammonium ion GO:0060359 71 0.011
negative regulation of transport GO:0051051 136 0.011
female mating behavior GO:0060180 6 0.011
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
negative regulation of protein autophosphorylation GO:0031953 2 0.011
drinking behavior GO:0042756 11 0.011
lung development GO:0030324 43 0.011
cellular macromolecule localization GO:0070727 122 0.011
small molecule biosynthetic process GO:0044283 124 0.011
regulation of hormone levels GO:0010817 187 0.011
response to growth factor GO:0070848 189 0.010
respiratory tube development GO:0030323 43 0.010
cell morphogenesis GO:0000902 142 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
cellular response to glucose stimulus GO:0071333 65 0.010
regulation of tube size GO:0035150 89 0.010
positive regulation of hormone secretion GO:0046887 65 0.010
response to mechanical stimulus GO:0009612 134 0.010
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.010
catecholamine secretion GO:0050432 33 0.010
urogenital system development GO:0001655 78 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010

Sftpb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.014
disease of anatomical entity DOID:7 0 0.014
Human
sensory system disease DOID:0050155 0 0.014
eye disease DOID:5614 0 0.011
eye and adnexa disease DOID:1492 0 0.011
retinal disease DOID:5679 0 0.011