Rattus norvegicus

0 known processes

Shox2

short stature homeobox 2

Shox2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.599
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.573
Mouse
positive regulation of rna biosynthetic process GO:1902680 197 0.496
Mouse
nucleic acid templated transcription GO:0097659 379 0.455
Mouse
signal transduction by phosphorylation GO:0023014 144 0.422
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.418
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.403
Mouse
rna biosynthetic process GO:0032774 380 0.396
Mouse
positive regulation of gene expression GO:0010628 244 0.381
Mouse
positive regulation of cell communication GO:0010647 271 0.367
Mouse
response to hypoxia GO:0001666 231 0.363
positive regulation of signal transduction GO:0009967 175 0.362
Mouse
cation transport GO:0006812 382 0.355
negative regulation of cellular biosynthetic process GO:0031327 161 0.349
Mouse
regulation of signal transduction GO:0009966 318 0.339
Mouse
transcription from rna polymerase ii promoter GO:0006366 252 0.339
Mouse
positive regulation of transcription dna templated GO:0045893 197 0.332
Mouse
rna metabolic process GO:0016070 406 0.326
Mouse
positive regulation of signaling GO:0023056 270 0.319
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.318
intracellular signal transduction GO:0035556 314 0.309
mapk cascade GO:0000165 140 0.304
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.299
Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.298
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.294
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.292
Mouse
tissue development GO:0009888 252 0.289
Mouse
positive regulation of cell proliferation GO:0008284 249 0.289
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.288
response to glucocorticoid GO:0051384 223 0.282
negative regulation of nucleic acid templated transcription GO:1903507 117 0.277
Mouse
prepulse inhibition GO:0060134 1 0.277
negative regulation of biosynthetic process GO:0009890 168 0.251
Mouse
regulation of cell proliferation GO:0042127 359 0.245
Mouse
negative regulation of gene expression GO:0010629 199 0.237
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.231
Mouse
cation transmembrane transport GO:0098655 263 0.228
head development GO:0060322 247 0.225
positive regulation of intracellular signal transduction GO:1902533 138 0.223
ureteric bud development GO:0001657 14 0.217
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.215
Mouse
transcription dna templated GO:0006351 377 0.210
Mouse
positive regulation of cellular biosynthetic process GO:0031328 295 0.199
Mouse
g protein coupled receptor signaling pathway GO:0007186 242 0.197
response to corticosteroid GO:0031960 235 0.192
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.191
Mouse
brain development GO:0007420 247 0.191
embryonic skeletal system morphogenesis GO:0048704 3 0.190
Mouse
homeostatic process GO:0042592 331 0.180
regulation of intracellular signal transduction GO:1902531 218 0.174
chemical homeostasis GO:0048878 292 0.173
regulation of system process GO:0044057 208 0.168
response to peptide GO:1901652 292 0.165
organ morphogenesis GO:0009887 75 0.164
Mouse
response to estradiol GO:0032355 164 0.164
regulation of neuron death GO:1901214 115 0.164
regulation of cell differentiation GO:0045595 320 0.164
Mouse
cyclic nucleotide metabolic process GO:0009187 80 0.162
negative regulation of rna biosynthetic process GO:1902679 118 0.162
Mouse
regulation of neuron apoptotic process GO:0043523 83 0.162
regulation of rna metabolic process GO:0051252 391 0.157
Mouse
anatomical structure morphogenesis GO:0009653 298 0.157
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.157
enzyme linked receptor protein signaling pathway GO:0007167 116 0.155
positive regulation of epithelial cell proliferation GO:0050679 32 0.154
cellular component morphogenesis GO:0032989 155 0.150
Mouse
connective tissue development GO:0061448 33 0.150
Mouse
forebrain development GO:0030900 98 0.149
neurological system process GO:0050877 219 0.146
positive regulation of molecular function GO:0044093 230 0.143
regulation of molecular function GO:0065009 398 0.141
positive regulation of nucleic acid templated transcription GO:1903508 197 0.139
Mouse
cellular response to peptide hormone stimulus GO:0071375 120 0.137
positive regulation of rna metabolic process GO:0051254 203 0.137
Mouse
negative regulation of cell death GO:0060548 229 0.137
regulation of phosphorylation GO:0042325 248 0.136
synaptic transmission GO:0007268 235 0.136
negative regulation of transcription dna templated GO:0045892 116 0.131
Mouse
organophosphate metabolic process GO:0019637 370 0.131
regulation of mapk cascade GO:0043408 116 0.130
cellular response to nitrogen compound GO:1901699 210 0.129
regulation of phosphorus metabolic process GO:0051174 349 0.129
positive regulation of multicellular organismal process GO:0051240 387 0.126
Mouse
response to oxygen levels GO:0070482 265 0.124
carbohydrate derivative metabolic process GO:1901135 346 0.123
cellular metal ion homeostasis GO:0006875 172 0.123
limb morphogenesis GO:0035108 4 0.123
Mouse
regulation of multicellular organismal development GO:2000026 376 0.121
Mouse
anion transport GO:0006820 178 0.118
regulation of ion transport GO:0043269 245 0.117
anterior posterior pattern specification GO:0009952 1 0.116
response to cytokine GO:0034097 215 0.116
kidney morphogenesis GO:0060993 13 0.116
regulation of cell development GO:0060284 263 0.115
Mouse
camp metabolic process GO:0046058 63 0.113
skeletal system development GO:0001501 41 0.110
Mouse
regulation of apoptotic process GO:0042981 335 0.108
regulation of canonical wnt signaling pathway GO:0060828 4 0.107
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.106
Mouse
positive regulation of transport GO:0051050 245 0.106
ribose phosphate metabolic process GO:0019693 235 0.105
sensory organ development GO:0007423 74 0.105
regulation of programmed cell death GO:0043067 341 0.102
programmed cell death GO:0012501 392 0.100
ribonucleotide metabolic process GO:0009259 231 0.099
response to growth factor GO:0070848 189 0.097
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.096
regulation of epithelial cell proliferation GO:0050678 49 0.095
cellular response to stress GO:0033554 269 0.095
mesonephros development GO:0001823 14 0.095
cell type specific apoptotic process GO:0097285 134 0.093
transmembrane transport GO:0055085 412 0.093
bone development GO:0060348 25 0.092
Mouse
secretion by cell GO:0032940 248 0.092
negative regulation of cellular metabolic process GO:0031324 281 0.090
Mouse
neuron death GO:0070997 127 0.090
mesonephric tubule development GO:0072164 14 0.088
intracellular transport GO:0046907 185 0.088
nucleobase containing small molecule metabolic process GO:0055086 316 0.088
response to peptide hormone GO:0043434 278 0.087
appendage morphogenesis GO:0035107 4 0.087
Mouse
embryonic skeletal system development GO:0048706 3 0.087
Mouse
positive regulation of kinase activity GO:0033674 77 0.084
neuromuscular process GO:0050905 2 0.084
tube development GO:0035295 89 0.083
Mouse
negative regulation of cell proliferation GO:0008285 119 0.083
macromolecule localization GO:0033036 252 0.082
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.082
Mouse
cartilage development GO:0051216 22 0.080
Mouse
response to decreased oxygen levels GO:0036293 237 0.080
potassium ion transport GO:0006813 97 0.079
nucleotide metabolic process GO:0009117 279 0.079
positive regulation of mapk cascade GO:0043410 92 0.078
gland development GO:0048732 155 0.076
specification of organ identity GO:0010092 2 0.076
calcium ion homeostasis GO:0055074 162 0.076
central nervous system development GO:0007417 311 0.076
cellular amino acid metabolic process GO:0006520 107 0.076
behavior GO:0007610 205 0.075
regulation of cyclase activity GO:0031279 21 0.075
nitrogen compound transport GO:0071705 229 0.075
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.075
Mouse
regulation of purine nucleotide metabolic process GO:1900542 115 0.075
organophosphate biosynthetic process GO:0090407 143 0.075
positive regulation of transferase activity GO:0051347 81 0.075
cellular response to abiotic stimulus GO:0071214 85 0.074
carbohydrate derivative biosynthetic process GO:1901137 124 0.074
cellular homeostasis GO:0019725 252 0.074
regulation of secretion GO:0051046 224 0.074
ossification GO:0001503 70 0.073
Mouse
establishment of protein localization GO:0045184 141 0.073
positive regulation of response to stimulus GO:0048584 285 0.073
Mouse
response to axon injury GO:0048678 59 0.072
protein localization GO:0008104 191 0.071
regulation of lipid biosynthetic process GO:0046890 38 0.071
purine nucleotide metabolic process GO:0006163 229 0.071
cardiovascular system development GO:0072358 134 0.070
Mouse
positive regulation of cellular component organization GO:0051130 200 0.070
Mouse
positive regulation of developmental process GO:0051094 283 0.070
Mouse
cellular response to organic cyclic compound GO:0071407 202 0.070
cytosolic calcium ion homeostasis GO:0051480 140 0.070
response to estrogen GO:0043627 232 0.069
response to acid chemical GO:0001101 222 0.067
tissue morphogenesis GO:0048729 22 0.067
Mouse
response to extracellular stimulus GO:0009991 380 0.066
response to nutrient levels GO:0031667 370 0.065
embryonic cranial skeleton morphogenesis GO:0048701 2 0.065
macromolecular complex assembly GO:0065003 273 0.065
hormone mediated signaling pathway GO:0009755 23 0.065
mesonephric epithelium development GO:0072163 14 0.064
locomotion GO:0040011 237 0.064
second messenger mediated signaling GO:0019932 51 0.063
nucleoside catabolic process GO:0009164 126 0.063
protein phosphorylation GO:0006468 345 0.062
regulation of adenylate cyclase activity GO:0045761 18 0.062
amine metabolic process GO:0009308 38 0.062
cellular component assembly GO:0022607 360 0.062
cellular response to hormone stimulus GO:0032870 247 0.062
cellular component biogenesis GO:0044085 368 0.062
neuropeptide signaling pathway GO:0007218 29 0.062
cellular cation homeostasis GO:0030003 180 0.061
negative regulation of cell communication GO:0010648 158 0.061
embryonic appendage morphogenesis GO:0035113 4 0.060
Mouse
purine ribonucleotide metabolic process GO:0009150 227 0.060
regulation of hormone levels GO:0010817 187 0.059
response to hexose GO:0009746 144 0.059
cellular chemical homeostasis GO:0055082 247 0.059
epithelial cell proliferation GO:0050673 54 0.059
cell cell signaling GO:0007267 335 0.059
renal system development GO:0072001 67 0.058
localization of cell GO:0051674 202 0.058
cellular ion homeostasis GO:0006873 184 0.057
positive regulation of ion transport GO:0043270 94 0.057
macromolecular complex subunit organization GO:0043933 339 0.056
anatomical structure formation involved in morphogenesis GO:0048646 83 0.056
reproductive process GO:0022414 372 0.056
morphogenesis of an epithelium GO:0002009 20 0.056
cellular response to oxygen containing compound GO:1901701 386 0.056
oxoacid metabolic process GO:0043436 290 0.055
response to metal ion GO:0010038 253 0.055
monovalent inorganic cation transport GO:0015672 172 0.055
purine nucleoside catabolic process GO:0006152 124 0.055
cellular response to growth factor stimulus GO:0071363 162 0.055
negative regulation of metabolic process GO:0009892 331 0.055
Mouse
neuron projection development GO:0031175 273 0.055
Mouse
negative regulation of transport GO:0051051 136 0.055
vesicle mediated transport GO:0016192 181 0.054
cognition GO:0050890 92 0.054
kidney epithelium development GO:0072073 19 0.054
positive regulation of cellular amine metabolic process GO:0033240 3 0.053
apoptotic process GO:0006915 381 0.053
single organism reproductive process GO:0044702 297 0.053
nucleoside phosphate metabolic process GO:0006753 283 0.052
single organism intracellular transport GO:1902582 166 0.052
positive regulation of phosphorus metabolic process GO:0010562 262 0.052
negative regulation of apoptotic process GO:0043066 181 0.052
positive regulation of secretion GO:0051047 140 0.051
positive regulation of neurogenesis GO:0050769 165 0.051
Mouse
cellular response to organonitrogen compound GO:0071417 197 0.050
positive regulation of cell differentiation GO:0045597 217 0.050
Mouse
protein complex subunit organization GO:0071822 302 0.049
regulation of catecholamine secretion GO:0050433 32 0.049
organic hydroxy compound transport GO:0015850 77 0.049
transmission of nerve impulse GO:0019226 42 0.048
negative regulation of molecular function GO:0044092 133 0.048
activation of protein kinase activity GO:0032147 47 0.048
regulation of cellular amine metabolic process GO:0033238 8 0.048
response to inorganic substance GO:0010035 377 0.048
regulation of membrane potential GO:0042391 110 0.048
startle response GO:0001964 2 0.047
regulation of homeostatic process GO:0032844 101 0.047
positive regulation of phosphorylation GO:0042327 177 0.047
positive regulation of cell development GO:0010720 176 0.047
Mouse
inorganic ion transmembrane transport GO:0098660 229 0.047
regulation of kinase activity GO:0043549 117 0.047
regulation of metal ion transport GO:0010959 118 0.046
cellular amine metabolic process GO:0044106 38 0.046
purine nucleotide biosynthetic process GO:0006164 83 0.045
hormone secretion GO:0046879 115 0.045
negative regulation of rna metabolic process GO:0051253 123 0.045
Mouse
amine transport GO:0015837 57 0.045
metal ion homeostasis GO:0055065 186 0.045
response to amphetamine GO:0001975 25 0.045
peptidyl amino acid modification GO:0018193 126 0.045
hormone transport GO:0009914 121 0.045
single organism catabolic process GO:0044712 283 0.044
negative regulation of signaling GO:0023057 157 0.044
regulation of cellular amino acid metabolic process GO:0006521 2 0.044
regulation of transmembrane transport GO:0034762 122 0.044
purine nucleoside triphosphate metabolic process GO:0009144 141 0.044
organic cyclic compound catabolic process GO:1901361 175 0.044
camera type eye development GO:0043010 48 0.044
erk1 and erk2 cascade GO:0070371 48 0.044
positive regulation of catalytic activity GO:0043085 184 0.044
protein complex assembly GO:0006461 263 0.044
respiratory system development GO:0060541 45 0.043
leukocyte activation GO:0045321 76 0.043
nucleoside phosphate biosynthetic process GO:1901293 102 0.043
carboxylic acid metabolic process GO:0019752 289 0.042
regulation of synaptic plasticity GO:0048167 70 0.042
aromatic compound catabolic process GO:0019439 168 0.042
reproduction GO:0000003 245 0.042
purine ribonucleotide biosynthetic process GO:0009152 81 0.042
ion homeostasis GO:0050801 212 0.041
negative regulation of neuron death GO:1901215 69 0.041
muscle tissue morphogenesis GO:0060415 1 0.041
Mouse
embryonic limb morphogenesis GO:0030326 4 0.041
Mouse
cellular response to insulin stimulus GO:0032869 81 0.041
regulation of hormone secretion GO:0046883 106 0.041
skeletal system morphogenesis GO:0048705 12 0.041
Mouse
response to transition metal nanoparticle GO:1990267 122 0.041
purine containing compound metabolic process GO:0072521 253 0.041
response to anoxia GO:0034059 4 0.041
camp biosynthetic process GO:0006171 47 0.040
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.040
growth GO:0040007 165 0.040
cellular protein localization GO:0034613 122 0.040
regulation of catalytic activity GO:0050790 304 0.040
regulation of ion transmembrane transport GO:0034765 121 0.040
regulation of nervous system development GO:0051960 264 0.040
Mouse
urogenital system development GO:0001655 78 0.039
regulation of protein phosphorylation GO:0001932 183 0.039
cellular response to lipid GO:0071396 201 0.039
response to mechanical stimulus GO:0009612 134 0.039
negative regulation of multicellular organismal process GO:0051241 203 0.039
organonitrogen compound biosynthetic process GO:1901566 167 0.038
protein complex biogenesis GO:0070271 263 0.038
nucleoside phosphate catabolic process GO:1901292 140 0.038
regulation of phosphate metabolic process GO:0019220 349 0.038
positive regulation of camp metabolic process GO:0030816 31 0.037
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.037
blood vessel development GO:0001568 69 0.037
cyclic nucleotide biosynthetic process GO:0009190 63 0.037
regulation of camp metabolic process GO:0030814 43 0.037
negative regulation of ion transport GO:0043271 51 0.037
positive regulation of protein kinase activity GO:0045860 73 0.037
cell motility GO:0048870 202 0.037
grooming behavior GO:0007625 4 0.037
neuron projection morphogenesis GO:0048812 122 0.037
Mouse
ribose phosphate biosynthetic process GO:0046390 87 0.037
chemosensory behavior GO:0007635 2 0.036
nephric duct development GO:0072176 1 0.036
positive regulation of protein phosphorylation GO:0001934 135 0.035
catabolic process GO:0009056 351 0.035
single organism biosynthetic process GO:0044711 342 0.035
embryo development GO:0009790 49 0.035
Mouse
osteoblast differentiation GO:0001649 26 0.035
Mouse
intracellular protein transport GO:0006886 79 0.035
olfactory learning GO:0008355 1 0.034
amide transport GO:0042886 105 0.034
s shaped body morphogenesis GO:0072050 2 0.034
cyclic purine nucleotide metabolic process GO:0052652 62 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.034
neuron apoptotic process GO:0051402 88 0.034
rhythmic process GO:0048511 156 0.034
regeneration GO:0031099 163 0.034
regulation of transferase activity GO:0051338 123 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.034
regulation of amine transport GO:0051952 54 0.034
heart development GO:0007507 72 0.033
Mouse
peptidyl tyrosine modification GO:0018212 72 0.033
negative regulation of neuron apoptotic process GO:0043524 45 0.033
positive regulation of nervous system development GO:0051962 178 0.033
Mouse
negative regulation of programmed cell death GO:0043069 183 0.033
palate development GO:0060021 2 0.033
peptidyl tyrosine phosphorylation GO:0018108 72 0.033
liver development GO:0001889 90 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.033
protein transport GO:0015031 132 0.032
divalent inorganic cation homeostasis GO:0072507 165 0.032
cell projection organization GO:0030030 302 0.032
Mouse
response to purine containing compound GO:0014074 126 0.032
positive regulation of glutamate secretion GO:0014049 8 0.032
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.032
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
Mouse
lipid biosynthetic process GO:0008610 128 0.032
muscle tissue development GO:0060537 58 0.032
Mouse
cellular response to metal ion GO:0071248 55 0.031
circadian rhythm GO:0007623 88 0.031
excretion GO:0007588 24 0.031
organic acid metabolic process GO:0006082 292 0.031
regulation of ossification GO:0030278 32 0.031
response to radiation GO:0009314 137 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
metal ion transport GO:0030001 289 0.031
regulation of neurogenesis GO:0050767 247 0.031
Mouse
organic acid transport GO:0015849 116 0.030
cellular divalent inorganic cation homeostasis GO:0072503 162 0.030
organic substance catabolic process GO:1901575 316 0.030
cellular response to cytokine stimulus GO:0071345 127 0.030
cellular response to peptide GO:1901653 133 0.030
circulatory system development GO:0072359 134 0.029
Mouse
positive regulation of secretion by cell GO:1903532 128 0.029
secretion GO:0046903 307 0.029
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.029
ribonucleotide biosynthetic process GO:0009260 85 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.029
Mouse
response to amine GO:0014075 46 0.029
purine nucleotide catabolic process GO:0006195 136 0.029
immune system development GO:0002520 41 0.029
positive regulation of jak stat cascade GO:0046427 19 0.029
regulation of amino acid transport GO:0051955 25 0.028
olfactory behavior GO:0042048 2 0.028
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.028
ribonucleoside triphosphate catabolic process GO:0009203 122 0.028
nucleotide biosynthetic process GO:0009165 98 0.028
cytoplasmic transport GO:0016482 115 0.028
regulation of nucleotide metabolic process GO:0006140 117 0.028
epithelium development GO:0060429 96 0.028
regulation of anatomical structure morphogenesis GO:0022603 141 0.028
Mouse
regulation of protein modification process GO:0031399 194 0.028
positive regulation of amino acid transport GO:0051957 13 0.028
regulation of neuronal synaptic plasticity GO:0048168 31 0.027
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.027
endocytosis GO:0006897 84 0.027
limb development GO:0060173 5 0.027
Mouse
regulation of cellular localization GO:0060341 263 0.027
regulation of glutamate secretion GO:0014048 17 0.027
positive regulation of neuron differentiation GO:0045666 126 0.027
Mouse
nucleoside triphosphate catabolic process GO:0009143 123 0.027
organophosphate catabolic process GO:0046434 148 0.027
regulation of organic acid transport GO:0032890 35 0.027
purine containing compound biosynthetic process GO:0072522 85 0.026
heterocycle catabolic process GO:0046700 167 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.026
muscle cell differentiation GO:0042692 52 0.026
Mouse
positive regulation of amine transport GO:0051954 26 0.026
single organism cellular localization GO:1902580 102 0.026
regulation of nucleotide biosynthetic process GO:0030808 47 0.026
organic anion transport GO:0015711 132 0.026
cellular calcium ion homeostasis GO:0006874 160 0.026
regulation of cellular component organization GO:0051128 368 0.026
Mouse
response to light stimulus GO:0009416 52 0.026
multi organism reproductive process GO:0044703 262 0.025
cellular ketone metabolic process GO:0042180 51 0.025
response to molecule of bacterial origin GO:0002237 194 0.025
neuron development GO:0048666 286 0.025
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
response to glucose GO:0009749 136 0.025
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.025
gastrulation GO:0007369 2 0.025
hormone metabolic process GO:0042445 69 0.025
regulation of secretion by cell GO:1903530 208 0.024
response to nutrient GO:0007584 248 0.024
dicarboxylic acid transport GO:0006835 34 0.024
regulation of organelle organization GO:0033043 80 0.024
taxis GO:0042330 67 0.024
calcium ion transport GO:0006816 131 0.024
striated muscle tissue development GO:0014706 58 0.024
Mouse
regulation of synaptic transmission GO:0050804 141 0.023
guanosine containing compound catabolic process GO:1901069 71 0.023
cation homeostasis GO:0055080 195 0.023
molting cycle process GO:0022404 2 0.023
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.023
insulin secretion GO:0030073 69 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
positive regulation of protein modification process GO:0031401 142 0.023
ribonucleoside triphosphate metabolic process GO:0009199 141 0.023
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.023
digestive system development GO:0055123 41 0.023
Mouse
response to lipopolysaccharide GO:0032496 191 0.023
gtp catabolic process GO:0006184 71 0.023
regulation of ion homeostasis GO:2000021 63 0.023
peptide transport GO:0015833 97 0.022
regulation of cell activation GO:0050865 50 0.022
immune system process GO:0002376 204 0.022
positive regulation of leukocyte degranulation GO:0043302 4 0.022
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.022
regulation of organ formation GO:0003156 2 0.022
muscle structure development GO:0061061 87 0.022
Mouse
regulation of protein localization GO:0032880 81 0.022
choline transport GO:0015871 4 0.022
negative regulation of camp metabolic process GO:0030815 14 0.022
organ formation GO:0048645 3 0.022
regulation of mesenchymal cell proliferation GO:0010464 4 0.022
Mouse
gland morphogenesis GO:0022612 12 0.022
nucleotide catabolic process GO:0009166 139 0.022
negative regulation of cell development GO:0010721 82 0.022
receptor mediated endocytosis GO:0006898 42 0.022
cellular response to alkaloid GO:0071312 25 0.022
positive regulation of synaptic transmission GO:0050806 62 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
negative regulation of secretion GO:0051048 82 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
heart growth GO:0060419 20 0.021
response to monosaccharide GO:0034284 159 0.021
regulation of protein kinase activity GO:0045859 105 0.021
kidney development GO:0001822 67 0.021
developmental induction GO:0031128 2 0.021
activation of janus kinase activity GO:0042976 5 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
purine nucleoside metabolic process GO:0042278 169 0.020
peptide secretion GO:0002790 86 0.020
regulation of lyase activity GO:0051339 22 0.020
negative regulation of phosphate metabolic process GO:0045936 80 0.020
regulation of blood circulation GO:1903522 110 0.020
regulation of response to external stimulus GO:0032101 106 0.020
response to alkaloid GO:0043279 132 0.020
purine containing compound catabolic process GO:0072523 138 0.020
single organism organelle organization GO:1902589 180 0.020
heart contraction GO:0060047 57 0.020
cell cycle process GO:0022402 57 0.020
locomotory behavior GO:0007626 15 0.020
metanephric glomerulus development GO:0072224 3 0.019
endocrine system development GO:0035270 30 0.019
regulation of protein metabolic process GO:0051246 289 0.019
mammary gland epithelium development GO:0061180 1 0.019
response to other organism GO:0051707 220 0.019
negative regulation of cell differentiation GO:0045596 99 0.019
steroid biosynthetic process GO:0006694 48 0.019
bmp signaling pathway GO:0030509 4 0.019
sequestering of metal ion GO:0051238 9 0.019
regulation of camp biosynthetic process GO:0030817 38 0.019
positive regulation of lipid biosynthetic process GO:0046889 25 0.019
organelle organization GO:0006996 266 0.019
behavioral response to ethanol GO:0048149 1 0.019
protein oligomerization GO:0051259 191 0.018
response to ethanol GO:0045471 162 0.018
muscle contraction GO:0006936 88 0.018
cellular response to inorganic substance GO:0071241 65 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
smooth muscle contraction GO:0006939 37 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
cellular response to lipopolysaccharide GO:0071222 55 0.018
insulin receptor signaling pathway GO:0008286 24 0.018
carbohydrate homeostasis GO:0033500 75 0.018
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.018
regulation of sodium ion transport GO:0002028 21 0.018
ribonucleoside metabolic process GO:0009119 174 0.018

Shox2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
musculoskeletal system disease DOID:17 0 0.060
bone development disease DOID:0080006 0 0.020
bone disease DOID:0080001 0 0.020
connective tissue disease DOID:65 0 0.020
disease of metabolism DOID:0014667 0 0.019