Rattus norvegicus

48 known processes

Siah1a

seven in absentia 1A

(Aliases: Siah1,SIAH)

Siah1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular metabolic process GO:0031324 281 0.475
rna metabolic process GO:0016070 406 0.446
negative regulation of rna metabolic process GO:0051253 123 0.394
transcription dna templated GO:0006351 377 0.385
nucleic acid templated transcription GO:0097659 379 0.317
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.287
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.274
rna biosynthetic process GO:0032774 380 0.270
negative regulation of metabolic process GO:0009892 331 0.265
regulation of transcription dna templated GO:0006355 374 0.245
regulation of rna metabolic process GO:0051252 391 0.213
negative regulation of cellular biosynthetic process GO:0031327 161 0.179
negative regulation of nucleic acid templated transcription GO:1903507 117 0.174
regulation of protein metabolic process GO:0051246 289 0.173
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.168
negative regulation of transcription dna templated GO:0045892 116 0.167
programmed cell death GO:0012501 392 0.166
regulation of rna biosynthetic process GO:2001141 381 0.164
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.149
negative regulation of biosynthetic process GO:0009890 168 0.127
apoptotic process GO:0006915 381 0.126
transcription from rna polymerase ii promoter GO:0006366 252 0.125
negative regulation of gene expression GO:0010629 199 0.124
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.111
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.111
intracellular signal transduction GO:0035556 314 0.109
regulation of nucleic acid templated transcription GO:1903506 380 0.105
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.104
negative regulation of macromolecule metabolic process GO:0010605 260 0.100
organelle organization GO:0006996 266 0.100
negative regulation of rna biosynthetic process GO:1902679 118 0.097
regulation of cellular protein metabolic process GO:0032268 267 0.095
positive regulation of gene expression GO:0010628 244 0.083
regulation of programmed cell death GO:0043067 341 0.082
positive regulation of cellular protein metabolic process GO:0032270 167 0.080
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.077
positive regulation of cellular biosynthetic process GO:0031328 295 0.068
positive regulation of rna metabolic process GO:0051254 203 0.064
positive regulation of cell communication GO:0010647 271 0.063
chromosome segregation GO:0007059 2 0.058
positive regulation of signal transduction GO:0009967 175 0.057
positive regulation of rna biosynthetic process GO:1902680 197 0.056
positive regulation of transcription dna templated GO:0045893 197 0.056
regulation of apoptotic process GO:0042981 335 0.055
regulation of signal transduction GO:0009966 318 0.055
positive regulation of biosynthetic process GO:0009891 319 0.054
regulation of catalytic activity GO:0050790 304 0.054
cellular response to oxygen containing compound GO:1901701 386 0.051
positive regulation of catalytic activity GO:0043085 184 0.051
positive regulation of signaling GO:0023056 270 0.050
cellular response to endogenous stimulus GO:0071495 377 0.050
positive regulation of response to stimulus GO:0048584 285 0.050
cellular catabolic process GO:0044248 295 0.049
anterior posterior pattern specification GO:0009952 1 0.049
negative regulation of cell death GO:0060548 229 0.049
central nervous system development GO:0007417 311 0.047
regulation of nervous system development GO:0051960 264 0.045
protein localization GO:0008104 191 0.044
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.044
catabolic process GO:0009056 351 0.043
macromolecular complex subunit organization GO:0043933 339 0.043
regulation of multicellular organismal development GO:2000026 376 0.042
positive regulation of molecular function GO:0044093 230 0.041
regulation of cell differentiation GO:0045595 320 0.041
reproduction GO:0000003 245 0.041
nucleoside phosphate metabolic process GO:0006753 283 0.040
cellular component assembly GO:0022607 360 0.040
positive regulation of cell death GO:0010942 184 0.040
positive regulation of cell motility GO:2000147 97 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.039
protein complex subunit organization GO:0071822 302 0.039
multicellular organismal reproductive process GO:0048609 233 0.038
positive regulation of developmental process GO:0051094 283 0.038
multicellular organism reproduction GO:0032504 233 0.037
neuron differentiation GO:0030182 368 0.037
negative regulation of multicellular organismal process GO:0051241 203 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.036
regulation of neuron differentiation GO:0045664 208 0.036
regulation of molecular function GO:0065009 398 0.035
sexual reproduction GO:0019953 148 0.035
regulation of cellular component organization GO:0051128 368 0.035
organic acid metabolic process GO:0006082 292 0.035
regulation of cell development GO:0060284 263 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.035
positive regulation of protein metabolic process GO:0051247 178 0.034
positive regulation of programmed cell death GO:0043068 157 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
cellular ketone metabolic process GO:0042180 51 0.033
amine metabolic process GO:0009308 38 0.033
regulation of phosphorylation GO:0042325 248 0.033
single organism reproductive process GO:0044702 297 0.033
endocytosis GO:0006897 84 0.032
neurological system process GO:0050877 219 0.032
brain development GO:0007420 247 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
cellular component biogenesis GO:0044085 368 0.032
negative regulation of response to stimulus GO:0048585 155 0.032
response to inorganic substance GO:0010035 377 0.032
single organism cellular localization GO:1902580 102 0.031
negative regulation of signaling GO:0023057 157 0.031
response to wounding GO:0009611 254 0.031
reproductive process GO:0022414 372 0.030
multi organism reproductive process GO:0044703 262 0.030
negative regulation of protein metabolic process GO:0051248 114 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
regulation of protein modification process GO:0031399 194 0.030
proteolysis GO:0006508 175 0.030
cellular response to stress GO:0033554 269 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.029
cytoskeleton organization GO:0007010 111 0.029
response to acid chemical GO:0001101 222 0.029
response to extracellular stimulus GO:0009991 380 0.028
positive regulation of apoptotic process GO:0043065 154 0.027
carboxylic acid metabolic process GO:0019752 289 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.026
response to bacterium GO:0009617 200 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
macromolecular complex assembly GO:0065003 273 0.026
gamete generation GO:0007276 124 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
mitotic spindle organization GO:0007052 2 0.025
positive regulation of protein phosphorylation GO:0001934 135 0.025
oxoacid metabolic process GO:0043436 290 0.025
protein complex assembly GO:0006461 263 0.025
regulation of cellular catabolic process GO:0031329 101 0.025
cell cycle GO:0007049 101 0.025
response to other organism GO:0051707 220 0.024
single organism organelle organization GO:1902589 180 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
single organism intracellular transport GO:1902582 166 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
negative regulation of cell communication GO:0010648 158 0.023
vesicle mediated transport GO:0016192 181 0.023
homeostatic process GO:0042592 331 0.023
action potential GO:0001508 54 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
regulation of neurogenesis GO:0050767 247 0.022
response to carbohydrate GO:0009743 183 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
reproductive structure development GO:0048608 128 0.022
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
cellular protein localization GO:0034613 122 0.021
gastrulation GO:0007369 2 0.021
aging GO:0007568 241 0.021
response to biotic stimulus GO:0009607 226 0.021
lipid metabolic process GO:0006629 283 0.021
response to external biotic stimulus GO:0043207 221 0.021
neuron development GO:0048666 286 0.021
cellular response to growth factor stimulus GO:0071363 162 0.020
cellular amine metabolic process GO:0044106 38 0.020
protein oligomerization GO:0051259 191 0.020
response to cytokine GO:0034097 215 0.020
dna metabolic process GO:0006259 96 0.020
peptidyl amino acid modification GO:0018193 126 0.019
regulation of proteasomal protein catabolic process GO:0061136 4 0.019
neuronal action potential GO:0019228 35 0.019
macromolecule localization GO:0033036 252 0.019
axis specification GO:0009798 4 0.019
response to hexose GO:0009746 144 0.019
growth GO:0040007 165 0.019
apoptotic signaling pathway GO:0097190 27 0.019
regulation of catabolic process GO:0009894 113 0.019
regulation of hydrolase activity GO:0051336 143 0.018
localization of cell GO:0051674 202 0.018
neuron projection development GO:0031175 273 0.018
negative regulation of developmental process GO:0051093 125 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
embryonic skeletal system morphogenesis GO:0048704 3 0.018
protein complex biogenesis GO:0070271 263 0.018
spindle organization GO:0007051 2 0.018
developmental process involved in reproduction GO:0003006 159 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
anion transport GO:0006820 178 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
cellular response to peptide GO:1901653 133 0.018
cellular chemical homeostasis GO:0055082 247 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
cellular response to lipid GO:0071396 201 0.017
response to decreased oxygen levels GO:0036293 237 0.017
locomotion GO:0040011 237 0.017
ras protein signal transduction GO:0007265 29 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
sex differentiation GO:0007548 113 0.017
response to oxidative stress GO:0006979 186 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
positive regulation of protein modification process GO:0031401 142 0.017
regeneration GO:0031099 163 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
regulation of cell proliferation GO:0042127 359 0.017
protein phosphorylation GO:0006468 345 0.017
tissue development GO:0009888 252 0.017
smad protein complex assembly GO:0007183 1 0.017
response to nutrient levels GO:0031667 370 0.016
response to heat GO:0009408 60 0.016
single organism catabolic process GO:0044712 283 0.016
positive regulation of cell development GO:0010720 176 0.016
biological adhesion GO:0022610 110 0.016
muscle structure development GO:0061061 87 0.016
meiotic cell cycle process GO:1903046 3 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
negative regulation of cell differentiation GO:0045596 99 0.016
positive regulation of transport GO:0051050 245 0.016
positive regulation of nervous system development GO:0051962 178 0.016
cell adhesion GO:0007155 110 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
cellular response to alcohol GO:0097306 87 0.015
cell migration GO:0016477 197 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
reproductive system development GO:0061458 128 0.015
negative regulation of transport GO:0051051 136 0.015
secretion GO:0046903 307 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
protein ubiquitination GO:0016567 28 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
response to radiation GO:0009314 137 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
nucleoside monophosphate metabolic process GO:0009123 93 0.015
chemical homeostasis GO:0048878 292 0.015
positive regulation of hydrolase activity GO:0051345 86 0.015
negative regulation of signal transduction GO:0009968 83 0.014
regulation of dna metabolic process GO:0051052 60 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
purine nucleoside monophosphate metabolic process GO:0009126 84 0.014
organ morphogenesis GO:0009887 75 0.014
regulation of proteolysis GO:0030162 66 0.014
response to monosaccharide GO:0034284 159 0.014
tube development GO:0035295 89 0.014
behavior GO:0007610 205 0.014
negative regulation of molecular function GO:0044092 133 0.014
regulation of transferase activity GO:0051338 123 0.014
organic acid transport GO:0015849 116 0.014
cellular component movement GO:0006928 248 0.014
embryonic pattern specification GO:0009880 1 0.014
response to growth factor GO:0070848 189 0.014
response to oxygen levels GO:0070482 265 0.014
response to mechanical stimulus GO:0009612 134 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
response to axon injury GO:0048678 59 0.014
mitotic cell cycle GO:0000278 49 0.014
response to glucose GO:0009749 136 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
cation homeostasis GO:0055080 195 0.014
cellular response to acid chemical GO:0071229 75 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
multicellular organismal signaling GO:0035637 44 0.013
regulation of membrane potential GO:0042391 110 0.013
intracellular protein transport GO:0006886 79 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
organic anion transport GO:0015711 132 0.013
embryo development GO:0009790 49 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
cellular component morphogenesis GO:0032989 155 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
nucleoside metabolic process GO:0009116 179 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
cell cycle process GO:0022402 57 0.013
eye morphogenesis GO:0048592 4 0.013
organic substance catabolic process GO:1901575 316 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
cell cell signaling GO:0007267 335 0.013
calcium ion homeostasis GO:0055074 162 0.013
protein processing GO:0016485 68 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
cell motility GO:0048870 202 0.012
single organism behavior GO:0044708 130 0.012
embryonic skeletal system development GO:0048706 3 0.012
cytoplasmic transport GO:0016482 115 0.012
nucleotide metabolic process GO:0009117 279 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
negative regulation of rna splicing GO:0033119 3 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of cell migration GO:0030334 128 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
male gamete generation GO:0048232 99 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
gonad development GO:0008406 104 0.012
developmental growth GO:0048589 100 0.012
response to metal ion GO:0010038 253 0.012
nucleoside catabolic process GO:0009164 126 0.012
cellular homeostasis GO:0019725 252 0.012
protein transport GO:0015031 132 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
purine containing compound metabolic process GO:0072521 253 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
cell projection organization GO:0030030 302 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.012
chromosome organization GO:0051276 36 0.012
centrosome organization GO:0051297 1 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
dephosphorylation GO:0016311 98 0.012
spermatogenesis GO:0007283 99 0.011
mapk cascade GO:0000165 140 0.011
secretion by cell GO:0032940 248 0.011
response to lipopolysaccharide GO:0032496 191 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
intracellular transport GO:0046907 185 0.011
gland development GO:0048732 155 0.011
regulation of secretion GO:0051046 224 0.011
response to peptide GO:1901652 292 0.011
carboxylic acid transport GO:0046942 115 0.011
protein modification by small protein conjugation or removal GO:0070647 35 0.011
protein targeting GO:0006605 61 0.011
response to hypoxia GO:0001666 231 0.011
monocarboxylic acid transport GO:0015718 52 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
regulation of locomotion GO:0040012 148 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
response to peptide hormone GO:0043434 278 0.010
regulation of peptidase activity GO:0052547 55 0.010
microtubule cytoskeleton organization GO:0000226 25 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
meiosis i GO:0007127 2 0.010
transmembrane transport GO:0055085 412 0.010
neuron death GO:0070997 127 0.010
activation of cysteine type endopeptidase activity GO:0097202 4 0.010

Siah1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.013
nervous system disease DOID:863 0 0.013