Rattus norvegicus

0 known processes

Sla

src-like adaptor

(Aliases: Slap1)

Sla biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 204 0.306
immune response GO:0006955 104 0.248
immune response regulating signaling pathway GO:0002764 19 0.167
cell activation GO:0001775 97 0.165
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.157
cation homeostasis GO:0055080 195 0.144
positive regulation of signaling GO:0023056 270 0.140
ion homeostasis GO:0050801 212 0.131
positive regulation of cell motility GO:2000147 97 0.129
immunoglobulin mediated immune response GO:0016064 4 0.126
defense response GO:0006952 194 0.121
intracellular signal transduction GO:0035556 314 0.117
response to biotic stimulus GO:0009607 226 0.106
positive regulation of cell communication GO:0010647 271 0.103
single organism intracellular transport GO:1902582 166 0.099
regulation of programmed cell death GO:0043067 341 0.098
metal ion homeostasis GO:0055065 186 0.096
localization of cell GO:0051674 202 0.092
regulation of b cell differentiation GO:0045577 1 0.091
calcium ion transport into cytosol GO:0060402 38 0.091
divalent inorganic cation homeostasis GO:0072507 165 0.089
positive regulation of response to stimulus GO:0048584 285 0.089
cellular metal ion homeostasis GO:0006875 172 0.086
regulation of immune system process GO:0002682 123 0.085
positive regulation of signal transduction GO:0009967 175 0.085
homeostatic process GO:0042592 331 0.081
positive regulation of immune system process GO:0002684 90 0.081
protein phosphorylation GO:0006468 345 0.080
cellular amine metabolic process GO:0044106 38 0.080
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.079
positive regulation of neurogenesis GO:0050769 165 0.076
mapk cascade GO:0000165 140 0.076
positive regulation of intracellular signal transduction GO:1902533 138 0.075
calcium ion homeostasis GO:0055074 162 0.074
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.069
signal transduction by phosphorylation GO:0023014 144 0.069
anatomical structure morphogenesis GO:0009653 298 0.069
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.068
immune response activating signal transduction GO:0002757 15 0.067
regulation of molecular function GO:0065009 398 0.067
leukocyte activation GO:0045321 76 0.067
positive regulation of immune response GO:0050778 42 0.065
positive regulation of cell differentiation GO:0045597 217 0.064
sequestering of metal ion GO:0051238 9 0.062
regulation of mapk cascade GO:0043408 116 0.060
regulation of intracellular signal transduction GO:1902531 218 0.059
regulation of cellular amino acid metabolic process GO:0006521 2 0.059
regulation of phosphate metabolic process GO:0019220 349 0.058
cellular ketone metabolic process GO:0042180 51 0.055
cellular component biogenesis GO:0044085 368 0.055
Yeast Rat
cation transport GO:0006812 382 0.055
positive regulation of phosphate metabolic process GO:0045937 262 0.054
positive regulation of transcription factor import into nucleus GO:0042993 4 0.053
sequestering of calcium ion GO:0051208 8 0.052
cellular amino acid metabolic process GO:0006520 107 0.051
response to extracellular stimulus GO:0009991 380 0.051
neuron differentiation GO:0030182 368 0.051
cellular component movement GO:0006928 248 0.050
protein localization GO:0008104 191 0.050
regulation of phosphorylation GO:0042325 248 0.049
positive regulation of phosphorus metabolic process GO:0010562 262 0.048
mast cell migration GO:0097531 4 0.048
regulation of signal transduction GO:0009966 318 0.048
single organism cellular localization GO:1902580 102 0.047
release of sequestered calcium ion into cytosol GO:0051209 25 0.047
cellular divalent inorganic cation homeostasis GO:0072503 162 0.047
neuron development GO:0048666 286 0.046
dephosphorylation GO:0016311 98 0.046
b cell differentiation GO:0030183 2 0.046
cellular ion homeostasis GO:0006873 184 0.045
regulation of apoptotic process GO:0042981 335 0.045
response to growth factor GO:0070848 189 0.044
immune effector process GO:0002252 53 0.044
cellular protein localization GO:0034613 122 0.043
cytokine biosynthetic process GO:0042089 3 0.042
apoptotic process GO:0006915 381 0.042
cellular chemical homeostasis GO:0055082 247 0.042
regulation of immune response GO:0050776 55 0.042
programmed cell death GO:0012501 392 0.041
cellular cation homeostasis GO:0030003 180 0.040
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.039
positive regulation of programmed cell death GO:0043068 157 0.039
positive regulation of transport GO:0051050 245 0.039
aging GO:0007568 241 0.039
Rat
divalent metal ion transport GO:0070838 132 0.038
multi organism reproductive process GO:0044703 262 0.038
activation of immune response GO:0002253 26 0.038
regulation of protein transport GO:0051223 68 0.037
positive regulation of developmental process GO:0051094 283 0.037
negative regulation of metabolic process GO:0009892 331 0.037
hematopoietic progenitor cell differentiation GO:0002244 2 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.035
macromolecular complex subunit organization GO:0043933 339 0.035
Yeast Rat
cellular calcium ion homeostasis GO:0006874 160 0.035
cytoplasmic transport GO:0016482 115 0.034
establishment of protein localization GO:0045184 141 0.034
regulation of rna metabolic process GO:0051252 391 0.034
cell motility GO:0048870 202 0.034
protein complex biogenesis GO:0070271 263 0.034
Yeast Rat
regulation of protein phosphorylation GO:0001932 183 0.034
metal ion transport GO:0030001 289 0.034
protein complex subunit organization GO:0071822 302 0.034
Yeast Rat
macromolecule localization GO:0033036 252 0.033
amine metabolic process GO:0009308 38 0.033
neuron death GO:0070997 127 0.033
response to bacterium GO:0009617 200 0.033
response to oxygen levels GO:0070482 265 0.033
single organism reproductive process GO:0044702 297 0.033
cellular macromolecule localization GO:0070727 122 0.033
positive regulation of phosphorylation GO:0042327 177 0.032
lymphocyte activation GO:0046649 43 0.032
regulation of transcription dna templated GO:0006355 374 0.032
cellular response to cytokine stimulus GO:0071345 127 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
cytosolic calcium ion homeostasis GO:0051480 140 0.032
calcium ion transport GO:0006816 131 0.032
regulation of cell differentiation GO:0045595 320 0.032
chemical homeostasis GO:0048878 292 0.031
organic acid metabolic process GO:0006082 292 0.031
regulation of catalytic activity GO:0050790 304 0.031
regulation of cytokine biosynthetic process GO:0042035 3 0.031
peptidyl amino acid modification GO:0018193 126 0.031
cellular response to stress GO:0033554 269 0.031
response to external biotic stimulus GO:0043207 221 0.031
cell cell signaling GO:0007267 335 0.030
negative regulation of response to stimulus GO:0048585 155 0.030
cell substrate adhesion GO:0031589 29 0.029
regulation of neurogenesis GO:0050767 247 0.029
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.029
cell type specific apoptotic process GO:0097285 134 0.029
reproductive process GO:0022414 372 0.029
b cell mediated immunity GO:0019724 4 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
cell migration GO:0016477 197 0.028
regulation of intracellular transport GO:0032386 65 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
positive regulation of apoptotic process GO:0043065 154 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
leukocyte mediated immunity GO:0002443 28 0.027
salivary gland morphogenesis GO:0007435 1 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.027
positive regulation of neuron differentiation GO:0045666 126 0.027
regulation of neuron apoptotic process GO:0043523 83 0.027
multicellular organismal reproductive process GO:0048609 233 0.027
response to alkyl hydroperoxide GO:0033195 1 0.027
response to insulin GO:0032868 133 0.027
positive regulation of cell activation GO:0050867 34 0.027
secretion by cell GO:0032940 248 0.027
regulation of neuron death GO:1901214 115 0.026
response to decreased oxygen levels GO:0036293 237 0.026
head development GO:0060322 247 0.026
hormone secretion GO:0046879 115 0.026
actin filament based process GO:0030029 86 0.026
Yeast
positive regulation of immunoglobulin production GO:0002639 4 0.026
regulation of secretion by cell GO:1903530 208 0.026
regulation of cellular extravasation GO:0002691 2 0.026
regulation of protein kinase activity GO:0045859 105 0.026
negative regulation of neuron apoptotic process GO:0043524 45 0.026
regulation of kinase activity GO:0043549 117 0.026
regulation of hormone levels GO:0010817 187 0.026
negative regulation of programmed cell death GO:0043069 183 0.025
cellular component assembly GO:0022607 360 0.025
Yeast Rat
nucleic acid templated transcription GO:0097659 379 0.025
response to hypoxia GO:0001666 231 0.025
salivary gland development GO:0007431 3 0.025
maintenance of location GO:0051235 17 0.025
multicellular organism reproduction GO:0032504 233 0.024
blood vessel development GO:0001568 69 0.024
positive regulation of cell death GO:0010942 184 0.024
positive regulation of isotype switching to igg isotypes GO:0048304 1 0.024
regulation of cell migration GO:0030334 128 0.024
central nervous system development GO:0007417 311 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
response to mechanical stimulus GO:0009612 134 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
cellular homeostasis GO:0019725 252 0.024
regulation of cellular localization GO:0060341 263 0.023
regulation of neuron projection development GO:0010975 161 0.023
gland development GO:0048732 155 0.023
regulation of b cell mediated immunity GO:0002712 2 0.023
positive regulation of cell development GO:0010720 176 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
muscle contraction GO:0006936 88 0.023
rna biosynthetic process GO:0032774 380 0.022
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.022
response to corticosteroid GO:0031960 235 0.022
antigen receptor mediated signaling pathway GO:0050851 1 0.022
regulation of ion transport GO:0043269 245 0.022
hematopoietic or lymphoid organ development GO:0048534 36 0.022
macromolecular complex assembly GO:0065003 273 0.022
Yeast Rat
regulation of transferase activity GO:0051338 123 0.022
cytokine mediated signaling pathway GO:0019221 43 0.022
response to nutrient levels GO:0031667 370 0.022
regulation of homeostatic process GO:0032844 101 0.022
actin filament bundle assembly GO:0051017 19 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
positive regulation of protein kinase activity GO:0045860 73 0.021
cellular carbohydrate metabolic process GO:0044262 72 0.021
regulation of immunoglobulin production GO:0002637 4 0.021
locomotion GO:0040011 237 0.021
positive regulation of cell projection organization GO:0031346 111 0.021
enzyme linked receptor protein signaling pathway GO:0007167 116 0.021
cell projection organization GO:0030030 302 0.021
biological adhesion GO:0022610 110 0.021
protein transport GO:0015031 132 0.021
muscle system process GO:0003012 115 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
cellular response to external stimulus GO:0071496 118 0.021
neurotrophin trk receptor signaling pathway GO:0048011 10 0.021
negative regulation of homeostatic process GO:0032845 47 0.021
purine containing compound metabolic process GO:0072521 253 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
b cell activation involved in immune response GO:0002312 1 0.020
regulation of dna metabolic process GO:0051052 60 0.020
regulation of cell proliferation GO:0042127 359 0.020
negative regulation of neuron death GO:1901215 69 0.020
reproduction GO:0000003 245 0.020
oxoacid metabolic process GO:0043436 290 0.020
regulation of cell development GO:0060284 263 0.020
regulation of locomotion GO:0040012 148 0.020
regulation of sequestering of calcium ion GO:0051282 26 0.020
cellular lipid metabolic process GO:0044255 208 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
leukocyte activation involved in immune response GO:0002366 16 0.020
cytoskeleton organization GO:0007010 111 0.020
Yeast
axis specification GO:0009798 4 0.020
brain development GO:0007420 247 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
negative regulation of signaling GO:0023057 157 0.019
organic hydroxy compound metabolic process GO:1901615 115 0.019
positive regulation of cell migration GO:0030335 96 0.019
nitrogen compound transport GO:0071705 229 0.019
fc receptor mediated stimulatory signaling pathway GO:0002431 3 0.019
regulation of calcium ion transport into cytosol GO:0010522 25 0.019
regulation of system process GO:0044057 208 0.019
response to toxic substance GO:0009636 133 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of protein metabolic process GO:0051246 289 0.018
regulation of protein modification process GO:0031399 194 0.018
olfactory learning GO:0008355 1 0.018
regulation of platelet activation GO:0010543 2 0.018
positive regulation of nervous system development GO:0051962 178 0.018
regulation of b cell proliferation GO:0030888 6 0.018
response to other organism GO:0051707 220 0.018
neuron apoptotic process GO:0051402 88 0.018
anterior posterior pattern specification GO:0009952 1 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
mononuclear cell proliferation GO:0032943 29 0.018
cytokine production GO:0001816 61 0.018
intracellular transport GO:0046907 185 0.018
organophosphate metabolic process GO:0019637 370 0.017
positive regulation of humoral immune response GO:0002922 2 0.017
motor neuron axon guidance GO:0008045 1 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
regulation of response to stress GO:0080134 126 0.017
regulation of nervous system development GO:0051960 264 0.017
negative regulation of chronic inflammatory response GO:0002677 2 0.017
positive regulation of intracellular protein transport GO:0090316 20 0.017
regulation of cell adhesion GO:0030155 52 0.017
protein autophosphorylation GO:0046777 66 0.017
regulation of protein serine threonine kinase activity GO:0071900 64 0.017
response to fatty acid GO:0070542 65 0.017
single organism organelle organization GO:1902589 180 0.017
Yeast
cellular response to organonitrogen compound GO:0071417 197 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
vesicle mediated transport GO:0016192 181 0.016
Yeast
positive regulation of neuron projection development GO:0010976 99 0.016
positive regulation of smooth muscle cell migration GO:0014911 27 0.016
regulation of cellular component movement GO:0051270 150 0.016
leukocyte cell cell adhesion GO:0007159 4 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
regulation of leukocyte proliferation GO:0070663 26 0.016
insulin receptor signaling pathway GO:0008286 24 0.016
circulatory system development GO:0072359 134 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
cell projection morphogenesis GO:0048858 123 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
positive regulation of gamma delta t cell activation GO:0046645 1 0.016
cellular response to insulin stimulus GO:0032869 81 0.016
neuron projection development GO:0031175 273 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.015
negative regulation of signal transduction GO:0009968 83 0.015
negative regulation of cell communication GO:0010648 158 0.015
positive regulation of molecular function GO:0044093 230 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
nuclear transport GO:0051169 49 0.015
developmental process involved in reproduction GO:0003006 159 0.015
positive regulation of cellular component movement GO:0051272 102 0.015
regulation of mononuclear cell proliferation GO:0032944 26 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
positive regulation of leukocyte activation GO:0002696 30 0.015
leukocyte aggregation GO:0070486 1 0.015
glial cell differentiation GO:0010001 65 0.015
cytokine metabolic process GO:0042107 6 0.015
leukocyte proliferation GO:0070661 29 0.015
positive regulation of lymphocyte proliferation GO:0050671 20 0.015
regulation of t cell proliferation GO:0042129 17 0.015
actin filament bundle organization GO:0061572 19 0.015
regulation of isotype switching GO:0045191 1 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
erythrocyte homeostasis GO:0034101 2 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
negative regulation of cell death GO:0060548 229 0.014
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.014
lipid metabolic process GO:0006629 283 0.014
positive regulation of gene expression GO:0010628 244 0.014
actin cytoskeleton organization GO:0030036 73 0.014
Yeast
positive regulation of protein modification process GO:0031401 142 0.014
positive regulation of immune effector process GO:0002699 19 0.013
activation of protein kinase b activity GO:0032148 3 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
gamma delta t cell differentiation GO:0042492 1 0.013
dna metabolic process GO:0006259 96 0.013
regulation of cell activation GO:0050865 50 0.013
membrane organization GO:0061024 94 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
rna metabolic process GO:0016070 406 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
negative regulation of sequestering of calcium ion GO:0051283 25 0.013
regulation of cellular component organization GO:0051128 368 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
response to vitamin GO:0033273 131 0.013
erk1 and erk2 cascade GO:0070371 48 0.013
phosphatidylinositol 3 kinase signaling GO:0014065 14 0.013
positive regulation of myeloid cell differentiation GO:0045639 7 0.012
positive regulation of kinase activity GO:0033674 77 0.012
positive regulation of nf kappab import into nucleus GO:0042346 2 0.012
mast cell chemotaxis GO:0002551 4 0.012
inflammatory response GO:0006954 150 0.012
positive regulation of secretion GO:0051047 140 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
mitotic spindle organization GO:0007052 2 0.012
cell cycle GO:0007049 101 0.012
gamete generation GO:0007276 124 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
regulation of response to wounding GO:1903034 69 0.012
heterotypic cell cell adhesion GO:0034113 2 0.012
positive regulation of leukocyte degranulation GO:0043302 4 0.012
signal release GO:0023061 145 0.012
myoblast fusion GO:0007520 2 0.012
regulation of ion homeostasis GO:2000021 63 0.012
positive regulation of fc receptor mediated stimulatory signaling pathway GO:0060369 1 0.012
regulation of cell motility GO:2000145 131 0.012
cellular response to oxidative stress GO:0034599 76 0.012
cellular response to peptide GO:1901653 133 0.012
progesterone receptor signaling pathway GO:0050847 1 0.012
peptide transport GO:0015833 97 0.012
regulation of actin filament based process GO:0032970 42 0.011
regulation of isotype switching to igg isotypes GO:0048302 1 0.011
response to peptide hormone GO:0043434 278 0.011
multicellular organismal homeostasis GO:0048871 49 0.011
tube development GO:0035295 89 0.011
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.011
regulation of cellular response to insulin stimulus GO:1900076 16 0.011
lipid storage GO:0019915 1 0.011
defense response to gram positive bacterium GO:0050830 2 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
embryonic pattern specification GO:0009880 1 0.011
cell adhesion GO:0007155 110 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
syncytium formation GO:0006949 4 0.011
response to radiation GO:0009314 137 0.011
positive regulation of leukocyte differentiation GO:1902107 13 0.011
negative regulation of molecular function GO:0044092 133 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
defense response to other organism GO:0098542 17 0.011
cytosolic calcium ion transport GO:0060401 39 0.011
positive regulation of cytokine production GO:0001819 42 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
t cell migration GO:0072678 2 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
spindle organization GO:0007051 2 0.011
protein complex assembly GO:0006461 263 0.011
Yeast Rat
regulation of multicellular organismal development GO:2000026 376 0.011
cardiovascular system development GO:0072358 134 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
organelle organization GO:0006996 266 0.010
Yeast
macrophage activation GO:0042116 15 0.010
regeneration GO:0031099 163 0.010
lymphocyte activation involved in immune response GO:0002285 3 0.010
response to peptide GO:1901652 292 0.010
response to oxidative stress GO:0006979 186 0.010
triglyceride homeostasis GO:0070328 2 0.010
positive regulation of transferase activity GO:0051347 81 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
sexual reproduction GO:0019953 148 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
response to purine containing compound GO:0014074 126 0.010
regulation of cytokinesis GO:0032465 3 0.010
transcription dna templated GO:0006351 377 0.010
phospholipid metabolic process GO:0006644 61 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
ribose phosphate metabolic process GO:0019693 235 0.010
regulation of neutrophil migration GO:1902622 6 0.010
embryonic axis specification GO:0000578 1 0.010
single organism cell adhesion GO:0098602 46 0.010
alcohol metabolic process GO:0006066 77 0.010

Sla disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
thyroid gland disease DOID:50 0 0.013
hypothyroidism DOID:1459 0 0.013
congenital hypothyroidism DOID:0050328 0 0.013
disease of anatomical entity DOID:7 0 0.013
endocrine system disease DOID:28 0 0.013