Rattus norvegicus

0 known processes

Slc12a4

solute carrier family 12 (potassium/chloride transporters), member 4

(Aliases: Kcc1)

Slc12a4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of phosphorus metabolic process GO:0051174 349 0.347
cell motility GO:0048870 202 0.330
regulation of signal transduction GO:0009966 318 0.231
cell migration GO:0016477 197 0.211
macromolecule localization GO:0033036 252 0.207
protein localization GO:0008104 191 0.191
locomotion GO:0040011 237 0.182
regulation of cellular localization GO:0060341 263 0.177
localization of cell GO:0051674 202 0.177
positive regulation of phosphorus metabolic process GO:0010562 262 0.175
regulation of catalytic activity GO:0050790 304 0.173
intracellular signal transduction GO:0035556 314 0.166
regulation of apoptotic process GO:0042981 335 0.157
regulation of cellular protein metabolic process GO:0032268 267 0.156
regulation of phosphorylation GO:0042325 248 0.152
positive regulation of phosphate metabolic process GO:0045937 262 0.152
response to hypoxia GO:0001666 231 0.142
anatomical structure morphogenesis GO:0009653 298 0.140
cellular component movement GO:0006928 248 0.139
nucleic acid templated transcription GO:0097659 379 0.138
apoptotic process GO:0006915 381 0.131
regulation of multicellular organismal development GO:2000026 376 0.131
protein phosphorylation GO:0006468 345 0.131
positive regulation of cell communication GO:0010647 271 0.128
regulation of molecular function GO:0065009 398 0.124
response to extracellular stimulus GO:0009991 380 0.117
catabolic process GO:0009056 351 0.115
regulation of cell migration GO:0030334 128 0.115
negative regulation of programmed cell death GO:0043069 183 0.114
biological adhesion GO:0022610 110 0.112
response to growth factor GO:0070848 189 0.109
tissue development GO:0009888 252 0.108
response to other organism GO:0051707 220 0.107
response to nutrient levels GO:0031667 370 0.106
regulation of phosphate metabolic process GO:0019220 349 0.105
regulation of protein metabolic process GO:0051246 289 0.105
rna metabolic process GO:0016070 406 0.103
positive regulation of developmental process GO:0051094 283 0.102
regulation of cellular component organization GO:0051128 368 0.101
regulation of programmed cell death GO:0043067 341 0.099
macromolecular complex subunit organization GO:0043933 339 0.098
regulation of transferase activity GO:0051338 123 0.097
cation transport GO:0006812 382 0.097
Rat
cellular component assembly GO:0022607 360 0.096
response to oxygen levels GO:0070482 265 0.095
secretion GO:0046903 307 0.093
regulation of rna metabolic process GO:0051252 391 0.091
programmed cell death GO:0012501 392 0.091
regulation of secretion GO:0051046 224 0.091
carbohydrate derivative metabolic process GO:1901135 346 0.091
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.089
negative regulation of metabolic process GO:0009892 331 0.089
response to decreased oxygen levels GO:0036293 237 0.089
actin filament based process GO:0030029 86 0.086
negative regulation of cell death GO:0060548 229 0.084
protein transport GO:0015031 132 0.084
mesoderm development GO:0007498 2 0.082
positive regulation of response to stimulus GO:0048584 285 0.082
carboxylic acid metabolic process GO:0019752 289 0.081
positive regulation of cell motility GO:2000147 97 0.081
cellular component biogenesis GO:0044085 368 0.081
regulation of secretion by cell GO:1903530 208 0.080
tissue morphogenesis GO:0048729 22 0.079
cell projection organization GO:0030030 302 0.078
positive regulation of signal transduction GO:0009967 175 0.078
purine containing compound metabolic process GO:0072521 253 0.078
ribose phosphate metabolic process GO:0019693 235 0.077
regulation of rna biosynthetic process GO:2001141 381 0.077
rna biosynthetic process GO:0032774 380 0.077
positive regulation of cellular protein metabolic process GO:0032270 167 0.077
regulation of nervous system development GO:0051960 264 0.076
secretion by cell GO:0032940 248 0.076
positive regulation of phosphorylation GO:0042327 177 0.076
protein complex subunit organization GO:0071822 302 0.076
neurological system process GO:0050877 219 0.076
ribonucleoside triphosphate catabolic process GO:0009203 122 0.076
response to external biotic stimulus GO:0043207 221 0.075
cell activation GO:0001775 97 0.075
establishment of protein localization GO:0045184 141 0.075
signal transduction by phosphorylation GO:0023014 144 0.074
positive regulation of multicellular organismal process GO:0051240 387 0.072
single organism organelle organization GO:1902589 180 0.071
cellular response to hormone stimulus GO:0032870 247 0.071
negative regulation of response to stimulus GO:0048585 155 0.070
cellular amino acid metabolic process GO:0006520 107 0.069
organelle organization GO:0006996 266 0.069
negative regulation of cellular metabolic process GO:0031324 281 0.069
oxoacid metabolic process GO:0043436 290 0.069
organic acid metabolic process GO:0006082 292 0.068
homeostatic process GO:0042592 331 0.068
Rat
positive regulation of cell differentiation GO:0045597 217 0.067
regulation of neuron differentiation GO:0045664 208 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.066
regulation of intracellular signal transduction GO:1902531 218 0.065
response to cytokine GO:0034097 215 0.065
behavior GO:0007610 205 0.064
purine nucleotide metabolic process GO:0006163 229 0.064
positive regulation of gene expression GO:0010628 244 0.064
regulation of protein modification process GO:0031399 194 0.063
negative regulation of cell communication GO:0010648 158 0.063
positive regulation of cellular biosynthetic process GO:0031328 295 0.063
cell cycle GO:0007049 101 0.062
cellular catabolic process GO:0044248 295 0.061
multicellular organism reproduction GO:0032504 233 0.061
regulation of protein localization GO:0032880 81 0.061
regulation of locomotion GO:0040012 148 0.061
positive regulation of molecular function GO:0044093 230 0.061
purine nucleoside catabolic process GO:0006152 124 0.060
regulation of nucleic acid templated transcription GO:1903506 380 0.060
peptidyl amino acid modification GO:0018193 126 0.060
positive regulation of intracellular signal transduction GO:1902533 138 0.060
negative regulation of apoptotic process GO:0043066 181 0.059
ribonucleoside catabolic process GO:0042454 126 0.059
gastrulation GO:0007369 2 0.059
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.058
regulation of neurogenesis GO:0050767 247 0.058
response to peptide hormone GO:0043434 278 0.058
ribonucleotide catabolic process GO:0009261 136 0.057
multicellular organismal reproductive process GO:0048609 233 0.057
response to bacterium GO:0009617 200 0.057
transcription dna templated GO:0006351 377 0.057
regulation of cellular component movement GO:0051270 150 0.057
cardiovascular system development GO:0072358 134 0.057
positive regulation of biosynthetic process GO:0009891 319 0.056
single organism catabolic process GO:0044712 283 0.056
positive regulation of signaling GO:0023056 270 0.056
purine ribonucleotide catabolic process GO:0009154 136 0.056
positive regulation of cell migration GO:0030335 96 0.056
reproduction GO:0000003 245 0.055
regulation of anatomical structure morphogenesis GO:0022603 141 0.055
positive regulation of protein phosphorylation GO:0001934 135 0.054
defense response GO:0006952 194 0.053
amine metabolic process GO:0009308 38 0.053
organophosphate metabolic process GO:0019637 370 0.053
regulation of cellular amine metabolic process GO:0033238 8 0.053
regulation of hydrolase activity GO:0051336 143 0.053
organonitrogen compound catabolic process GO:1901565 179 0.053
cellular response to oxygen containing compound GO:1901701 386 0.053
purine ribonucleoside catabolic process GO:0046130 124 0.053
purine ribonucleotide metabolic process GO:0009150 227 0.053
wound healing GO:0042060 122 0.053
positive regulation of neurogenesis GO:0050769 165 0.053
positive regulation of cell development GO:0010720 176 0.052
organophosphate catabolic process GO:0046434 148 0.052
response to wounding GO:0009611 254 0.052
positive regulation of cellular component movement GO:0051272 102 0.052
regulation of ion transport GO:0043269 245 0.052
positive regulation of cell death GO:0010942 184 0.052
organic substance catabolic process GO:1901575 316 0.052
regulation of protein phosphorylation GO:0001932 183 0.051
positive regulation of catalytic activity GO:0043085 184 0.051
nucleotide metabolic process GO:0009117 279 0.051
response to inorganic substance GO:0010035 377 0.051
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.051
transmission of nerve impulse GO:0019226 42 0.050
reproductive process GO:0022414 372 0.050
cellular chemical homeostasis GO:0055082 247 0.049
Rat
positive regulation of nervous system development GO:0051962 178 0.049
cytoskeleton organization GO:0007010 111 0.049
cell cell signaling GO:0007267 335 0.049
positive regulation of protein modification process GO:0031401 142 0.049
regulation of cell proliferation GO:0042127 359 0.049
response to metal ion GO:0010038 253 0.049
cellular amine metabolic process GO:0044106 38 0.049
regulation of cellular ketone metabolic process GO:0010565 27 0.048
response to vitamin GO:0033273 131 0.048
response to biotic stimulus GO:0009607 226 0.048
cellular response to endogenous stimulus GO:0071495 377 0.047
protein import GO:0017038 37 0.047
regulation of kinase activity GO:0043549 117 0.047
regulation of cellular amino acid metabolic process GO:0006521 2 0.047
limb morphogenesis GO:0035108 4 0.046
aging GO:0007568 241 0.046
multi organism reproductive process GO:0044703 262 0.045
connective tissue development GO:0061448 33 0.045
enzyme linked receptor protein signaling pathway GO:0007167 116 0.045
nucleoside catabolic process GO:0009164 126 0.044
negative regulation of multicellular organismal process GO:0051241 203 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.044
aromatic compound catabolic process GO:0019439 168 0.044
defense response to other organism GO:0098542 17 0.044
growth GO:0040007 165 0.044
ribonucleotide metabolic process GO:0009259 231 0.044
purine nucleotide catabolic process GO:0006195 136 0.043
cellular response to stress GO:0033554 269 0.043
nucleobase containing small molecule metabolic process GO:0055086 316 0.043
proteolysis GO:0006508 175 0.043
central nervous system development GO:0007417 311 0.043
epithelium development GO:0060429 96 0.043
regulation of cell motility GO:2000145 131 0.043
regulation of cell differentiation GO:0045595 320 0.043
chemical homeostasis GO:0048878 292 0.042
Rat
single organism intracellular transport GO:1902582 166 0.042
protein complex assembly GO:0006461 263 0.042
circulatory system process GO:0003013 183 0.042
positive regulation of cellular component organization GO:0051130 200 0.041
membrane organization GO:0061024 94 0.041
positive regulation of apoptotic process GO:0043065 154 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.041
carbohydrate derivative catabolic process GO:1901136 147 0.041
organ morphogenesis GO:0009887 75 0.040
purine nucleoside triphosphate metabolic process GO:0009144 141 0.040
positive regulation of rna biosynthetic process GO:1902680 197 0.040
mechanoreceptor differentiation GO:0042490 2 0.040
ribonucleoside metabolic process GO:0009119 174 0.040
negative regulation of signaling GO:0023057 157 0.039
regulation of protein transport GO:0051223 68 0.039
g protein coupled receptor signaling pathway GO:0007186 242 0.039
multicellular organismal signaling GO:0035637 44 0.039
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.039
nucleoside phosphate metabolic process GO:0006753 283 0.039
protein secretion GO:0009306 34 0.039
cellular ketone metabolic process GO:0042180 51 0.039
positive regulation of transcription dna templated GO:0045893 197 0.038
negative regulation of nervous system development GO:0051961 79 0.038
gland development GO:0048732 155 0.038
positive regulation of programmed cell death GO:0043068 157 0.038
response to carbohydrate GO:0009743 183 0.038
positive regulation of kinase activity GO:0033674 77 0.038
single organism reproductive process GO:0044702 297 0.038
heterocycle catabolic process GO:0046700 167 0.037
actin cytoskeleton organization GO:0030036 73 0.037
regulation of catabolic process GO:0009894 113 0.037
positive regulation of protein metabolic process GO:0051247 178 0.037
nucleobase containing compound catabolic process GO:0034655 152 0.037
regulation of purine nucleotide metabolic process GO:1900542 115 0.036
organic cyclic compound catabolic process GO:1901361 175 0.036
small gtpase mediated signal transduction GO:0007264 36 0.036
sexual reproduction GO:0019953 148 0.036
purine ribonucleoside metabolic process GO:0046128 168 0.036
positive regulation of cell projection organization GO:0031346 111 0.036
cellular homeostasis GO:0019725 252 0.036
Rat
lipid metabolic process GO:0006629 283 0.035
glycosyl compound catabolic process GO:1901658 126 0.035
cation transmembrane transport GO:0098655 263 0.035
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.035
blood circulation GO:0008015 183 0.034
positive regulation of locomotion GO:0040017 102 0.034
negative regulation of cellular component organization GO:0051129 83 0.034
regulation of cell morphogenesis GO:0022604 77 0.034
macromolecular complex assembly GO:0065003 273 0.034
nucleoside metabolic process GO:0009116 179 0.034
protein complex biogenesis GO:0070271 263 0.034
muscle structure development GO:0061061 87 0.034
embryonic appendage morphogenesis GO:0035113 4 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.033
positive regulation of rna metabolic process GO:0051254 203 0.033
regulation of cell projection organization GO:0031344 175 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.033
mapk cascade GO:0000165 140 0.033
cell adhesion GO:0007155 110 0.033
single organism biosynthetic process GO:0044711 342 0.033
negative regulation of phosphorus metabolic process GO:0010563 80 0.033
muscle system process GO:0003012 115 0.033
positive regulation of mapk cascade GO:0043410 92 0.032
nucleoside phosphate catabolic process GO:1901292 140 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.032
heart process GO:0003015 57 0.032
heart morphogenesis GO:0003007 3 0.032
positive regulation of neuron differentiation GO:0045666 126 0.032
endocytosis GO:0006897 84 0.032
protein oligomerization GO:0051259 191 0.032
nucleoside triphosphate metabolic process GO:0009141 144 0.031
regulation of protein kinase activity GO:0045859 105 0.031
response to organophosphorus GO:0046683 102 0.031
head development GO:0060322 247 0.031
neuron differentiation GO:0030182 368 0.031
regulation of system process GO:0044057 208 0.031
regeneration GO:0031099 163 0.031
nucleotide catabolic process GO:0009166 139 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.031
positive regulation of nucleotide metabolic process GO:0045981 91 0.031
cellular response to cytokine stimulus GO:0071345 127 0.031
cellular response to growth factor stimulus GO:0071363 162 0.031
circulatory system development GO:0072359 134 0.031
negative regulation of cell differentiation GO:0045596 99 0.031
divalent metal ion transport GO:0070838 132 0.031
vesicle mediated transport GO:0016192 181 0.031
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.030
regulation of transcription dna templated GO:0006355 374 0.030
purine nucleoside metabolic process GO:0042278 169 0.030
regulation of proteasomal protein catabolic process GO:0061136 4 0.030
urogenital system development GO:0001655 78 0.030
cellular ion homeostasis GO:0006873 184 0.029
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.029
cell part morphogenesis GO:0032990 123 0.029
lipid biosynthetic process GO:0008610 128 0.029
inflammatory response GO:0006954 150 0.029
regulation of establishment of protein localization GO:0070201 69 0.029
cellular protein localization GO:0034613 122 0.029
response to nutrient GO:0007584 248 0.029
regulation of membrane potential GO:0042391 110 0.029
angiogenesis GO:0001525 53 0.029
positive regulation of transport GO:0051050 245 0.028
cell projection morphogenesis GO:0048858 123 0.028
neuron projection development GO:0031175 273 0.028
neuron development GO:0048666 286 0.028
response to molecule of bacterial origin GO:0002237 194 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
positive regulation of cellular amine metabolic process GO:0033240 3 0.028
cellular component morphogenesis GO:0032989 155 0.027
regulation of nucleotide catabolic process GO:0030811 65 0.027
ion transmembrane transport GO:0034220 365 0.027
Rat
ion homeostasis GO:0050801 212 0.027
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.027
synaptic transmission GO:0007268 235 0.027
neuronal action potential GO:0019228 35 0.027
anterior posterior pattern specification GO:0009952 1 0.027
response to peptide GO:1901652 292 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
anatomical structure formation involved in morphogenesis GO:0048646 83 0.026
tissue regeneration GO:0042246 36 0.026
blood vessel development GO:0001568 69 0.026
regulation of mapk cascade GO:0043408 116 0.026
transmembrane transport GO:0055085 412 0.026
Rat
negative regulation of developmental process GO:0051093 125 0.026
apoptotic signaling pathway GO:0097190 27 0.026
metal ion homeostasis GO:0055065 186 0.026
cell growth GO:0016049 104 0.026
nucleoside triphosphate catabolic process GO:0009143 123 0.026
positive regulation of cell proliferation GO:0008284 249 0.025
response to amino acid GO:0043200 75 0.025
divalent inorganic cation transport GO:0072511 134 0.025
immune response GO:0006955 104 0.025
positive regulation of protein kinase activity GO:0045860 73 0.025
developmental growth GO:0048589 100 0.025
immune system process GO:0002376 204 0.025
axon ensheathment GO:0008366 40 0.024
vascular process in circulatory system GO:0003018 96 0.024
intracellular transport GO:0046907 185 0.024
reactive oxygen species metabolic process GO:0072593 37 0.024
small molecule biosynthetic process GO:0044283 124 0.024
regulation of cell development GO:0060284 263 0.024
calcium ion transport GO:0006816 131 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
negative regulation of molecular function GO:0044092 133 0.024
embryo development GO:0009790 49 0.024
response to corticosteroid GO:0031960 235 0.024
regulation of protein secretion GO:0050708 28 0.024
muscle tissue development GO:0060537 58 0.023
myelination GO:0042552 39 0.023
regulation of hormone levels GO:0010817 187 0.023
intracellular protein transport GO:0006886 79 0.023
gamete generation GO:0007276 124 0.023
ras protein signal transduction GO:0007265 29 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
cellular response to oxygen levels GO:0071453 60 0.023
brain development GO:0007420 247 0.023
cognition GO:0050890 92 0.023
bmp signaling pathway GO:0030509 4 0.022
protein targeting GO:0006605 61 0.022
response to starvation GO:0042594 59 0.022
muscle tissue morphogenesis GO:0060415 1 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
fatty acid metabolic process GO:0006631 99 0.022
regulation of blood vessel size GO:0050880 89 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
calcium ion homeostasis GO:0055074 162 0.022
response to monosaccharide GO:0034284 159 0.022
cell morphogenesis GO:0000902 142 0.022
glial cell differentiation GO:0010001 65 0.022
response to acid chemical GO:0001101 222 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
regulation of map kinase activity GO:0043405 53 0.021
skin morphogenesis GO:0043589 2 0.021
response to lipopolysaccharide GO:0032496 191 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 7 0.021
positive regulation of transferase activity GO:0051347 81 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
Rat
formation of primary germ layer GO:0001704 1 0.021
negative regulation of gene expression GO:0010629 199 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
cellular macromolecule localization GO:0070727 122 0.021
regulation of cellular component biogenesis GO:0044087 86 0.021
gliogenesis GO:0042063 93 0.021
positive regulation of hydrolase activity GO:0051345 86 0.021
regulation of tube size GO:0035150 89 0.021
regulation of stem cell differentiation GO:2000736 2 0.021
regulation of anatomical structure size GO:0090066 135 0.021
cellular cation homeostasis GO:0030003 180 0.021
Rat
response to glucose GO:0009749 136 0.021
negative regulation of transport GO:0051051 136 0.021
action potential GO:0001508 54 0.020
axon development GO:0061564 96 0.020
negative regulation of signal transduction GO:0009968 83 0.020
regulation of response to external stimulus GO:0032101 106 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
regulation of cell cycle GO:0051726 73 0.020
regulation of protein serine threonine kinase activity GO:0071900 64 0.020
cytoplasmic transport GO:0016482 115 0.020
cellular response to tumor necrosis factor GO:0071356 46 0.020
cyclic nucleotide metabolic process GO:0009187 80 0.020
regulation of cellular catabolic process GO:0031329 101 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
positive regulation of neuron projection development GO:0010976 99 0.020
heart contraction GO:0060047 57 0.020
cellular calcium ion homeostasis GO:0006874 160 0.020
divalent inorganic cation homeostasis GO:0072507 165 0.020
cell cycle process GO:0022402 57 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
single organism membrane organization GO:0044802 74 0.020
chemotaxis GO:0006935 66 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.020
muscle organ morphogenesis GO:0048644 1 0.020
positive regulation of protein transport GO:0051222 41 0.020
single organism cellular localization GO:1902580 102 0.020
response to heat GO:0009408 60 0.020
tube development GO:0035295 89 0.020
neuron fate commitment GO:0048663 4 0.020
reproductive system development GO:0061458 128 0.019
learning or memory GO:0007611 90 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
ribonucleoside triphosphate metabolic process GO:0009199 141 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
response to purine containing compound GO:0014074 126 0.019
negative regulation of neuron differentiation GO:0045665 62 0.019
guanosine containing compound catabolic process GO:1901069 71 0.019
digestive system development GO:0055123 41 0.019
purine nucleoside triphosphate catabolic process GO:0009146 122 0.019
negative regulation of catalytic activity GO:0043086 103 0.018
regulation of growth GO:0040008 105 0.018
response to estradiol GO:0032355 164 0.018
regulation of immune system process GO:0002682 123 0.018
vasculature development GO:0001944 70 0.018
organ formation GO:0048645 3 0.018
embryonic limb morphogenesis GO:0030326 4 0.018
regulation of response to wounding GO:1903034 69 0.018
neuron death GO:0070997 127 0.018
regulation of reactive oxygen species metabolic process GO:2000377 26 0.018
female pregnancy GO:0007565 122 0.018
response to hexose GO:0009746 144 0.018
response to temperature stimulus GO:0009266 94 0.018
reproductive structure development GO:0048608 128 0.018
purine containing compound catabolic process GO:0072523 138 0.018
negative regulation of cell development GO:0010721 82 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
Rat
heart development GO:0007507 72 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
response to ketone GO:1901654 182 0.018
macromolecule catabolic process GO:0009057 58 0.018
extrinsic apoptotic signaling pathway GO:0097191 10 0.017
appendage morphogenesis GO:0035107 4 0.017
endomembrane system organization GO:0010256 48 0.017
small molecule catabolic process GO:0044282 59 0.017
hair cell differentiation GO:0035315 2 0.017
regulation of ossification GO:0030278 32 0.017
neuron projection morphogenesis GO:0048812 122 0.017
developmental process involved in reproduction GO:0003006 159 0.017
protein autophosphorylation GO:0046777 66 0.017
cyclic nucleotide biosynthetic process GO:0009190 63 0.017
oxidation reduction process GO:0055114 304 0.017
protein heterooligomerization GO:0051291 89 0.017
peptidyl lysine hydroxylation GO:0017185 1 0.017
cell fate determination GO:0001709 2 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
amide transport GO:0042886 105 0.017
respiratory system development GO:0060541 45 0.017
response to alkaloid GO:0043279 132 0.017
forebrain development GO:0030900 98 0.016
organic acid biosynthetic process GO:0016053 83 0.016
embryonic pattern specification GO:0009880 1 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
extracellular structure organization GO:0043062 13 0.016
embryonic cranial skeleton morphogenesis GO:0048701 2 0.016
blood vessel morphogenesis GO:0048514 58 0.016
negative regulation of osteoblast differentiation GO:0045668 2 0.016
dna metabolic process GO:0006259 96 0.016
regulation of muscle system process GO:0090257 79 0.016
response to estrogen GO:0043627 232 0.016
atp catabolic process GO:0006200 54 0.016
lung development GO:0030324 43 0.016
nucleocytoplasmic transport GO:0006913 48 0.016
cytokine production GO:0001816 61 0.016
multi multicellular organism process GO:0044706 138 0.016
male gamete generation GO:0048232 99 0.016
positive regulation of secretion GO:0051047 140 0.016

Slc12a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.454
musculoskeletal system disease DOID:17 0 0.454
muscular disease DOID:0080000 0 0.207
myopathy DOID:423 0 0.207
muscle tissue disease DOID:66 0 0.207
muscular dystrophy DOID:9884 0 0.075
nervous system disease DOID:863 0 0.074
cardiovascular system disease DOID:1287 0 0.069
connective tissue disease DOID:65 0 0.042
bone development disease DOID:0080006 0 0.025
bone disease DOID:0080001 0 0.025
heart disease DOID:114 0 0.023
cardiomyopathy DOID:0050700 0 0.023
sensory system disease DOID:0050155 0 0.022
neuromuscular disease DOID:440 0 0.021
neuropathy DOID:870 0 0.021
disease of metabolism DOID:0014667 0 0.019
intrinsic cardiomyopathy DOID:0060036 0 0.016