Rattus norvegicus

35 known processes

Slc19a1

solute carrier family 19 (folate transporter), member 1

(Aliases: MGC93506,MTX1)

Slc19a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.138
carboxylic acid metabolic process GO:0019752 289 0.097
organic acid metabolic process GO:0006082 292 0.089
cofactor metabolic process GO:0051186 95 0.076
cellular amino acid metabolic process GO:0006520 107 0.063
regulation of apoptotic process GO:0042981 335 0.058
organophosphate metabolic process GO:0019637 370 0.058
cellular lipid metabolic process GO:0044255 208 0.057
regulation of programmed cell death GO:0043067 341 0.052
response to nutrient levels GO:0031667 370 0.047
response to extracellular stimulus GO:0009991 380 0.046
single organism biosynthetic process GO:0044711 342 0.043
programmed cell death GO:0012501 392 0.041
catabolic process GO:0009056 351 0.040
single organism catabolic process GO:0044712 283 0.040
regulation of cellular amino acid metabolic process GO:0006521 2 0.040
regulation of molecular function GO:0065009 398 0.040
apoptotic process GO:0006915 381 0.039
cellular amine metabolic process GO:0044106 38 0.039
response to transition metal nanoparticle GO:1990267 122 0.038
amine metabolic process GO:0009308 38 0.038
cellular ketone metabolic process GO:0042180 51 0.037
coenzyme metabolic process GO:0006732 86 0.037
central nervous system development GO:0007417 311 0.037
cellular response to oxygen containing compound GO:1901701 386 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.036
macromolecule localization GO:0033036 252 0.036
positive regulation of molecular function GO:0044093 230 0.036
lipid metabolic process GO:0006629 283 0.035
positive regulation of apoptotic process GO:0043065 154 0.035
nitrogen compound transport GO:0071705 229 0.035
cellular catabolic process GO:0044248 295 0.034
regulation of catalytic activity GO:0050790 304 0.034
alpha amino acid metabolic process GO:1901605 71 0.034
proteolysis GO:0006508 175 0.032
multicellular organismal reproductive process GO:0048609 233 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.030
organic substance catabolic process GO:1901575 316 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.029
cell cell signaling GO:0007267 335 0.029
neuron differentiation GO:0030182 368 0.029
protein phosphorylation GO:0006468 345 0.029
response to nutrient GO:0007584 248 0.029
cation transport GO:0006812 382 0.029
macromolecular complex assembly GO:0065003 273 0.028
response to peptide hormone GO:0043434 278 0.028
anatomical structure morphogenesis GO:0009653 298 0.028
tetrahydrofolate metabolic process GO:0046653 9 0.028
brain development GO:0007420 247 0.027
reproduction GO:0000003 245 0.027
nucleotide metabolic process GO:0009117 279 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
regulation of protein metabolic process GO:0051246 289 0.025
protein oligomerization GO:0051259 191 0.025
regulation of proteasomal protein catabolic process GO:0061136 4 0.025
reproductive structure development GO:0048608 128 0.025
reproductive process GO:0022414 372 0.025
reproductive system development GO:0061458 128 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
multicellular organism reproduction GO:0032504 233 0.024
response to metal ion GO:0010038 253 0.024
negative regulation of cell death GO:0060548 229 0.024
response to hexose GO:0009746 144 0.024
cellular component assembly GO:0022607 360 0.023
response to monosaccharide GO:0034284 159 0.023
rna metabolic process GO:0016070 406 0.023
gonad development GO:0008406 104 0.023
organelle organization GO:0006996 266 0.023
regulation of phosphorylation GO:0042325 248 0.023
purine containing compound metabolic process GO:0072521 253 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.022
aging GO:0007568 241 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
homeostatic process GO:0042592 331 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.021
single organism reproductive process GO:0044702 297 0.021
gland development GO:0048732 155 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
pteridine containing compound metabolic process GO:0042558 14 0.021
cell projection organization GO:0030030 302 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
positive regulation of cell death GO:0010942 184 0.021
small molecule biosynthetic process GO:0044283 124 0.021
protein maturation GO:0051604 68 0.020
regulation of hormone levels GO:0010817 187 0.020
chemical homeostasis GO:0048878 292 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
negative regulation of signaling GO:0023057 157 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
negative regulation of apoptotic process GO:0043066 181 0.019
response to peptide GO:1901652 292 0.019
response to glucose GO:0009749 136 0.019
heart morphogenesis GO:0003007 3 0.019
cell type specific apoptotic process GO:0097285 134 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
protein complex assembly GO:0006461 263 0.018
tissue development GO:0009888 252 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
oxidation reduction process GO:0055114 304 0.018
establishment of protein localization GO:0045184 141 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
regulation of signal transduction GO:0009966 318 0.018
rhythmic process GO:0048511 156 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
synaptic transmission GO:0007268 235 0.018
developmental process involved in reproduction GO:0003006 159 0.017
development of primary female sexual characteristics GO:0046545 56 0.017
protein complex biogenesis GO:0070271 263 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
response to carbohydrate GO:0009743 183 0.017
regulation of transferase activity GO:0051338 123 0.017
response to inorganic substance GO:0010035 377 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
regulation of membrane potential GO:0042391 110 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
vitamin transport GO:0051180 14 0.017
regulation of protein localization GO:0032880 81 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
regulation of cell projection organization GO:0031344 175 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.017
axis specification GO:0009798 4 0.017
response to biotic stimulus GO:0009607 226 0.017
secretion GO:0046903 307 0.017
gastrulation GO:0007369 2 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
response to growth factor GO:0070848 189 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
response to oxygen levels GO:0070482 265 0.016
response to acid chemical GO:0001101 222 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
development of primary sexual characteristics GO:0045137 107 0.016
response to bacterium GO:0009617 200 0.016
neuron projection development GO:0031175 273 0.016
limb morphogenesis GO:0035108 4 0.016
response to cytokine GO:0034097 215 0.016
neuron development GO:0048666 286 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
response to ethanol GO:0045471 162 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
response to other organism GO:0051707 220 0.015
cellular component biogenesis GO:0044085 368 0.015
regulation of cell proliferation GO:0042127 359 0.015
cytoskeleton dependent cytokinesis GO:0061640 2 0.015
organic hydroxy compound transport GO:0015850 77 0.015
nucleic acid templated transcription GO:0097659 379 0.015
regulation of cellular component organization GO:0051128 368 0.015
response to decreased oxygen levels GO:0036293 237 0.015
multi organism reproductive process GO:0044703 262 0.015
ion homeostasis GO:0050801 212 0.015
fatty acid metabolic process GO:0006631 99 0.015
lipid biosynthetic process GO:0008610 128 0.015
chromosome segregation GO:0007059 2 0.015
cation transmembrane transport GO:0098655 263 0.015
transmembrane transport GO:0055085 412 0.015
ras protein signal transduction GO:0007265 29 0.015
negative regulation of molecular function GO:0044092 133 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
heterocycle catabolic process GO:0046700 167 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
glial cell differentiation GO:0010001 65 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
carboxylic acid transport GO:0046942 115 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
intracellular signal transduction GO:0035556 314 0.014
cardiovascular system development GO:0072358 134 0.014
positive regulation of cell communication GO:0010647 271 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
head development GO:0060322 247 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
dna metabolic process GO:0006259 96 0.014
regulation of neurogenesis GO:0050767 247 0.014
cellular macromolecule localization GO:0070727 122 0.013
gamete generation GO:0007276 124 0.013
anion transport GO:0006820 178 0.013
circulatory system development GO:0072359 134 0.013
protein homooligomerization GO:0051260 91 0.013
rna biosynthetic process GO:0032774 380 0.013
cofactor biosynthetic process GO:0051188 28 0.013
regulation of proteolysis GO:0030162 66 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
bmp signaling pathway GO:0030509 4 0.013
cellular response to stress GO:0033554 269 0.013
positive regulation of signal transduction GO:0009967 175 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
organic anion transport GO:0015711 132 0.013
regulation of catabolic process GO:0009894 113 0.013
protein localization GO:0008104 191 0.013
ion transmembrane transport GO:0034220 365 0.013
negative regulation of gene expression GO:0010629 199 0.013
hexose metabolic process GO:0019318 58 0.013
organic acid biosynthetic process GO:0016053 83 0.013
metal ion transport GO:0030001 289 0.012
folic acid containing compound metabolic process GO:0006760 10 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
response to toxic substance GO:0009636 133 0.012
regulation of protein maturation GO:1903317 50 0.012
response to axon injury GO:0048678 59 0.012
locomotion GO:0040011 237 0.012
biological adhesion GO:0022610 110 0.012
regulation of neuron projection development GO:0010975 161 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
cellular response to external stimulus GO:0071496 118 0.012
cation homeostasis GO:0055080 195 0.012
sex differentiation GO:0007548 113 0.012
positive regulation of transport GO:0051050 245 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
regeneration GO:0031099 163 0.012
positive regulation of signaling GO:0023056 270 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
eye morphogenesis GO:0048592 4 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
regulation of neuron differentiation GO:0045664 208 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
appendage morphogenesis GO:0035107 4 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
microtubule organizing center organization GO:0031023 1 0.012
protein processing GO:0016485 68 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
growth GO:0040007 165 0.012
embryonic limb morphogenesis GO:0030326 4 0.012
neurological system process GO:0050877 219 0.011
response to oxidative stress GO:0006979 186 0.011
cellular response to peptide GO:1901653 133 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
regulation of system process GO:0044057 208 0.011
regulation of mapk cascade GO:0043408 116 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
regulation of protein kinase activity GO:0045859 105 0.011
transcription dna templated GO:0006351 377 0.011
positive regulation of cell development GO:0010720 176 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
intracellular transport GO:0046907 185 0.011
response to external biotic stimulus GO:0043207 221 0.011
positive regulation of mitochondrion organization GO:0010822 4 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
amino acid transport GO:0006865 70 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
regulation of protein processing GO:0070613 50 0.011
cell cycle checkpoint GO:0000075 2 0.011
protein complex subunit organization GO:0071822 302 0.011
organophosphate catabolic process GO:0046434 148 0.011
protein transport GO:0015031 132 0.011
regulation of secretion GO:0051046 224 0.011
regulation of nervous system development GO:0051960 264 0.011
cellular homeostasis GO:0019725 252 0.011
neuron death GO:0070997 127 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.011
secretion by cell GO:0032940 248 0.011
regulation of protein modification process GO:0031399 194 0.010
cellular modified amino acid metabolic process GO:0006575 61 0.010
gliogenesis GO:0042063 93 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
small molecule catabolic process GO:0044282 59 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
single organism organelle organization GO:1902589 180 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
regulation of meiotic cell cycle GO:0051445 3 0.010
male sex differentiation GO:0046661 64 0.010
cytoplasmic transport GO:0016482 115 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
response to hypoxia GO:0001666 231 0.010
response to purine containing compound GO:0014074 126 0.010

Slc19a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.011
disease of anatomical entity DOID:7 0 0.011
inherited metabolic disorder DOID:655 0 0.010
disease of metabolism DOID:0014667 0 0.010