Rattus norvegicus

31 known processes

Slc23a1

solute carrier family 23 (nucleobase transporters), member 1

(Aliases: SVCT1)

Slc23a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glutathione transport GO:0034635 2 0.427
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.388
cellular lipid metabolic process GO:0044255 208 0.356
lipid metabolic process GO:0006629 283 0.348
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.317
vitamin d receptor signaling pathway GO:0070561 1 0.311
carboxylic acid metabolic process GO:0019752 289 0.301
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.274
linoleic acid metabolic process GO:0043651 4 0.263
drug transmembrane transport GO:0006855 13 0.262
naphthalene containing compound metabolic process GO:0090420 2 0.224
monocarboxylic acid transport GO:0015718 52 0.213
small molecule catabolic process GO:0044282 59 0.188
naphthalene metabolic process GO:0018931 2 0.175
drug catabolic process GO:0042737 1 0.168
response to inorganic substance GO:0010035 377 0.160
organic hydroxy compound metabolic process GO:1901615 115 0.160
oxoacid metabolic process GO:0043436 290 0.155
Rat
fatty acid metabolic process GO:0006631 99 0.154
oxidation reduction process GO:0055114 304 0.152
ion transmembrane transport GO:0034220 365 0.134
exogenous drug catabolic process GO:0042738 1 0.133
drug transport GO:0015893 18 0.126
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.125
quaternary ammonium group transport GO:0015697 6 0.124
vitamin a metabolic process GO:0006776 2 0.115
response to acid chemical GO:0001101 222 0.114
regulation of telomerase activity GO:0051972 2 0.111
carboxylic acid transport GO:0046942 115 0.108
sorbitol biosynthetic process GO:0006061 1 0.101
nitrogen cycle metabolic process GO:0071941 5 0.100
organic acid biosynthetic process GO:0016053 83 0.099
organic acid metabolic process GO:0006082 292 0.095
Rat
antibiotic transport GO:0042891 2 0.094
cellular hormone metabolic process GO:0034754 49 0.093
tripeptide transport GO:0042939 2 0.092
organic substance catabolic process GO:1901575 316 0.089
oligopeptide transport GO:0006857 4 0.089
carnitine transport GO:0015879 1 0.086
halogenated hydrocarbon metabolic process GO:0042197 4 0.084
organophosphate metabolic process GO:0019637 370 0.081
reproductive process GO:0022414 372 0.080
sodium independent organic anion transport GO:0043252 2 0.079
cellular response to stress GO:0033554 269 0.077
cellular homeostasis GO:0019725 252 0.077
collecting duct development GO:0072044 1 0.075
behavioral response to nicotine GO:0035095 2 0.075
multi organism reproductive process GO:0044703 262 0.075
mrna transcription GO:0009299 2 0.075
trichloroethylene metabolic process GO:0018979 1 0.074
nitrogen compound transport GO:0071705 229 0.073
epoxygenase p450 pathway GO:0019373 1 0.072
pancreatic stellate cell proliferation GO:0072343 2 0.071
cellular catabolic process GO:0044248 295 0.070
phenol containing compound metabolic process GO:0018958 30 0.069
terpenoid metabolic process GO:0006721 37 0.069
response to estradiol GO:0032355 164 0.067
organonitrogen compound biosynthetic process GO:1901566 167 0.067
lauric acid metabolic process GO:0048252 4 0.066
response to oxidative stress GO:0006979 186 0.066
Rat
response to metformin GO:1901558 1 0.066
catabolic process GO:0009056 351 0.065
rna metabolic process GO:0016070 406 0.064
single organism biosynthetic process GO:0044711 342 0.063
inner medullary collecting duct development GO:0072061 1 0.062
drug metabolic process GO:0017144 11 0.062
response to sulfur dioxide GO:0010477 3 0.062
nicotine metabolic process GO:0018933 1 0.061
cofactor metabolic process GO:0051186 95 0.061
transcription from rna polymerase ii promoter GO:0006366 252 0.060
response to corticosteroid GO:0031960 235 0.060
anion transport GO:0006820 178 0.058
choline transport GO:0015871 4 0.058
response to ketone GO:1901654 182 0.058
organic cation transport GO:0015695 11 0.056
sorbitol metabolic process GO:0006060 1 0.055
response to ethanol GO:0045471 162 0.055
chlorinated hydrocarbon metabolic process GO:0042196 4 0.055
regulation of hormone levels GO:0010817 187 0.055
cellular response to vitamin e GO:0071306 3 0.055
retinal metabolic process GO:0042574 3 0.053
response to estrogen GO:0043627 232 0.053
regulation of phagocytosis engulfment GO:0060099 4 0.052
aging GO:0007568 241 0.052
long chain fatty acid metabolic process GO:0001676 32 0.051
response to cesium ion GO:0010164 2 0.051
diterpenoid metabolic process GO:0016101 33 0.050
protein complex biogenesis GO:0070271 263 0.050
cation transport GO:0006812 382 0.049
nucleic acid templated transcription GO:0097659 379 0.049
smooth muscle cell proliferation GO:0048659 77 0.049
single organism catabolic process GO:0044712 283 0.048
cell cell signaling GO:0007267 335 0.047
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.047
protein complex subunit organization GO:0071822 302 0.046
organic anion transport GO:0015711 132 0.046
response to radiation GO:0009314 137 0.046
coumarin metabolic process GO:0009804 5 0.045
isoprenoid metabolic process GO:0006720 45 0.045
sterol homeostasis GO:0055092 3 0.045
macromolecular complex assembly GO:0065003 273 0.044
protein complex assembly GO:0006461 263 0.044
secretion GO:0046903 307 0.042
toxin transport GO:1901998 3 0.042
response to nutrient levels GO:0031667 370 0.042
lipid localization GO:0010876 62 0.042
response to metal ion GO:0010038 253 0.042
small molecule biosynthetic process GO:0044283 124 0.041
cellular response to oxygen containing compound GO:1901701 386 0.041
organophosphate biosynthetic process GO:0090407 143 0.040
positive regulation of phagocytosis engulfment GO:0060100 4 0.040
regulation of smooth muscle cell proliferation GO:0048660 75 0.040
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
arachidonic acid metabolic process GO:0019369 20 0.039
response to molecule of fungal origin GO:0002238 3 0.039
cellular component assembly GO:0022607 360 0.039
positive regulation of gene expression GO:0010628 244 0.039
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.038
cellular ketone metabolic process GO:0042180 51 0.038
secretion by cell GO:0032940 248 0.038
multi multicellular organism process GO:0044706 138 0.037
multicellular organismal reproductive process GO:0048609 233 0.037
positive regulation of developmental process GO:0051094 283 0.037
regulation of blood pressure GO:0008217 83 0.036
retinoid metabolic process GO:0001523 24 0.036
fatty acid oxidation GO:0019395 29 0.036
fatty acid transport GO:0015908 25 0.036
central nervous system development GO:0007417 311 0.036
coenzyme metabolic process GO:0006732 86 0.036
lipid transport GO:0006869 61 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
organic hydroxy compound transport GO:0015850 77 0.034
head development GO:0060322 247 0.033
negative regulation of molecular function GO:0044092 133 0.033
rna biosynthetic process GO:0032774 380 0.033
alkaloid metabolic process GO:0009820 3 0.033
cellular component biogenesis GO:0044085 368 0.033
circadian rhythm GO:0007623 88 0.032
carboxylic acid biosynthetic process GO:0046394 83 0.032
organelle organization GO:0006996 266 0.032
ion homeostasis GO:0050801 212 0.032
protein homooligomerization GO:0051260 91 0.032
carboxylic acid catabolic process GO:0046395 49 0.032
hexitol biosynthetic process GO:0019406 1 0.031
regulation of metal ion transport GO:0010959 118 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
aromatic amino acid family catabolic process GO:0009074 7 0.031
positive regulation of ion transport GO:0043270 94 0.031
sulfur compound metabolic process GO:0006790 70 0.030
positive regulation of transcription dna templated GO:0045893 197 0.030
cellular response to lipid GO:0071396 201 0.030
indole containing compound metabolic process GO:0042430 11 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
negative regulation of metabolic process GO:0009892 331 0.030
macromolecule localization GO:0033036 252 0.030
female pregnancy GO:0007565 122 0.030
generation of precursor metabolites and energy GO:0006091 62 0.030
icosanoid metabolic process GO:0006690 38 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
reproduction GO:0000003 245 0.029
nucleotide biosynthetic process GO:0009165 98 0.029
fatty acid derivative metabolic process GO:1901568 38 0.029
alpha amino acid metabolic process GO:1901605 71 0.028
response to external biotic stimulus GO:0043207 221 0.028
defense response GO:0006952 194 0.028
acetyl coa metabolic process GO:0006084 17 0.028
lipid modification GO:0030258 52 0.028
carbohydrate metabolic process GO:0005975 130 0.028
Rat
negative regulation of telomerase activity GO:0051974 1 0.028
regulation of cell differentiation GO:0045595 320 0.028
response to interleukin 1 GO:0070555 55 0.027
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.027
cellular metal ion homeostasis GO:0006875 172 0.027
lipid oxidation GO:0034440 30 0.027
response to glucocorticoid GO:0051384 223 0.027
organic acid transport GO:0015849 116 0.027
multicellular organism growth GO:0035264 1 0.027
unsaturated fatty acid metabolic process GO:0033559 39 0.027
cellular response to growth factor stimulus GO:0071363 162 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
response to amine GO:0014075 46 0.025
response to extracellular stimulus GO:0009991 380 0.025
apoptotic process GO:0006915 381 0.025
epinephrine transport GO:0048241 7 0.025
inflammatory response GO:0006954 150 0.024
liver development GO:0001889 90 0.024
monovalent inorganic cation transport GO:0015672 172 0.024
cellular carbohydrate metabolic process GO:0044262 72 0.024
regulation of cellular localization GO:0060341 263 0.024
response to growth factor GO:0070848 189 0.024
serotonin metabolic process GO:0042428 3 0.024
homeostatic process GO:0042592 331 0.024
signal release GO:0023061 145 0.024
protein oligomerization GO:0051259 191 0.024
response to peptide hormone GO:0043434 278 0.024
regulation of ion transport GO:0043269 245 0.023
thioester metabolic process GO:0035383 28 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
growth GO:0040007 165 0.023
brain development GO:0007420 247 0.023
response to peptide GO:1901652 292 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
catechol containing compound metabolic process GO:0009712 19 0.023
response to biotic stimulus GO:0009607 226 0.023
fluorene metabolic process GO:0018917 1 0.023
regulation of transcription dna templated GO:0006355 374 0.023
regulation of secretion by cell GO:1903530 208 0.022
organic acid catabolic process GO:0016054 49 0.022
cellular response to steroid hormone stimulus GO:0071383 93 0.022
response to carbohydrate GO:0009743 183 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
rhythmic process GO:0048511 156 0.022
amide transport GO:0042886 105 0.022
pyridine containing compound metabolic process GO:0072524 32 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
norepinephrine metabolic process GO:0042415 3 0.021
cyclic nucleotide metabolic process GO:0009187 80 0.021
organic hydroxy compound biosynthetic process GO:1901617 51 0.021
single organism behavior GO:0044708 130 0.020
cation homeostasis GO:0055080 195 0.020
single organism carbohydrate metabolic process GO:0044723 118 0.020
Rat
single organism organelle organization GO:1902589 180 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
cellular response to methylglyoxal GO:0097238 1 0.020
amino acid betaine transport GO:0015838 1 0.020
regulation of system process GO:0044057 208 0.020
amine metabolic process GO:0009308 38 0.020
cation transmembrane transport GO:0098655 263 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
metal ion transport GO:0030001 289 0.019
positive regulation of transport GO:0051050 245 0.019
regulation of fat cell differentiation GO:0045598 3 0.019
multicellular organism reproduction GO:0032504 233 0.019
vesicle mediated transport GO:0016192 181 0.019
regulation of cell proliferation GO:0042127 359 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
response to calcium ion GO:0051592 59 0.019
cellular response to oxygen levels GO:0071453 60 0.018
phospholipid metabolic process GO:0006644 61 0.018
4 nitrophenol metabolic process GO:0018960 1 0.018
cellular amine metabolic process GO:0044106 38 0.018
cellular cation homeostasis GO:0030003 180 0.018
single organism reproductive process GO:0044702 297 0.018
glycerolipid metabolic process GO:0046486 67 0.018
response to fatty acid GO:0070542 65 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
acylglycerol metabolic process GO:0006639 21 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
renal system development GO:0072001 67 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
regulation of response to external stimulus GO:0032101 106 0.017
response to toxic substance GO:0009636 133 0.017
Human
inorganic cation transmembrane transport GO:0098662 202 0.017
lipid storage GO:0019915 1 0.017
purine containing compound metabolic process GO:0072521 253 0.017
chemical homeostasis GO:0048878 292 0.017
behavior GO:0007610 205 0.017
cellular response to ketone GO:1901655 51 0.017
regulation of endocytosis GO:0030100 42 0.017
sodium ion transport GO:0006814 82 0.017
regulation of rna metabolic process GO:0051252 391 0.017
forebrain development GO:0030900 98 0.016
response to cytokine GO:0034097 215 0.016
cellular response to alcohol GO:0097306 87 0.016
cell motility GO:0048870 202 0.016
response to starvation GO:0042594 59 0.016
response to xenobiotic stimulus GO:0009410 23 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
regulation of secretion GO:0051046 224 0.016
cellular response to extracellular stimulus GO:0031668 73 0.016
tissue development GO:0009888 252 0.016
catecholamine transport GO:0051937 37 0.016
regulation of cell migration GO:0030334 128 0.016
regulation of calcium ion transport GO:0051924 77 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
canalicular bile acid transport GO:0015722 5 0.015
monocarboxylic acid catabolic process GO:0072329 28 0.015
telencephalon development GO:0021537 62 0.015
regulation of cellular component organization GO:0051128 368 0.015
sensory perception of bitter taste GO:0050913 4 0.015
neutral lipid metabolic process GO:0006638 21 0.015
regulation of locomotion GO:0040012 148 0.015
biphenyl metabolic process GO:0018879 10 0.015
response to mechanical stimulus GO:0009612 134 0.015
regulation of apoptotic process GO:0042981 335 0.015
response to cocaine GO:0042220 39 0.015
alcohol metabolic process GO:0006066 77 0.015
response to vitamin GO:0033273 131 0.015
response to insulin GO:0032868 133 0.015
regulation of generation of precursor metabolites and energy GO:0043467 18 0.015
membrane organization GO:0061024 94 0.015
regulation of transcription regulatory region dna binding GO:2000677 4 0.015
long chain fatty acid transport GO:0015909 14 0.015
response to osmotic stress GO:0006970 42 0.015
b cell activation involved in immune response GO:0002312 1 0.015
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
transcription dna templated GO:0006351 377 0.014
adult locomotory behavior GO:0008344 4 0.014
cholesterol homeostasis GO:0042632 3 0.014
monoamine transport GO:0015844 43 0.014
calcium ion homeostasis GO:0055074 162 0.014
phospholipid biosynthetic process GO:0008654 29 0.014
response to vitamin d GO:0033280 34 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
cell growth GO:0016049 104 0.014
catecholamine metabolic process GO:0006584 19 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
protein localization GO:0008104 191 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
cell migration GO:0016477 197 0.014
glycogen metabolic process GO:0005977 23 0.014
regulation of cell projection organization GO:0031344 175 0.014
negative regulation of secretion GO:0051048 82 0.013
sulfur compound transport GO:0072348 8 0.013
response to testosterone GO:0033574 55 0.013
developmental growth GO:0048589 100 0.013
transmembrane transport GO:0055085 412 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
adult behavior GO:0030534 16 0.013
negative regulation of secretion by cell GO:1903531 72 0.013
regulation of carbohydrate metabolic process GO:0006109 41 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
endocytosis GO:0006897 84 0.013
regulation of programmed cell death GO:0043067 341 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
intestinal absorption GO:0050892 3 0.013
response to hexose GO:0009746 144 0.013
energy derivation by oxidation of organic compounds GO:0015980 46 0.012
regulation of phagocytosis GO:0050764 13 0.012
glucan metabolic process GO:0044042 23 0.012
hormone metabolic process GO:0042445 69 0.012
dicarboxylic acid metabolic process GO:0043648 42 0.012
response to monosaccharide GO:0034284 159 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
gland development GO:0048732 155 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
divalent metal ion transport GO:0070838 132 0.012
negative regulation of camp metabolic process GO:0030815 14 0.012
urea metabolic process GO:0019627 5 0.012
blood circulation GO:0008015 183 0.012
negative regulation of nucleotide metabolic process GO:0045980 23 0.012
female sex differentiation GO:0046660 59 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
cellular response to prostaglandin stimulus GO:0071379 7 0.012
negative regulation of collagen biosynthetic process GO:0032966 4 0.012
lens fiber cell differentiation GO:0070306 3 0.012
organ formation GO:0048645 3 0.012
fatty acid transmembrane transport GO:1902001 3 0.012
sulfation GO:0051923 2 0.011
regulation of cell growth GO:0001558 85 0.011
memory GO:0007613 54 0.011
cellular response to oxidative stress GO:0034599 76 0.011
regulation of insulin secretion GO:0050796 65 0.011
cellular response to glucocorticoid stimulus GO:0071385 68 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
sexual reproduction GO:0019953 148 0.011
regeneration GO:0031099 163 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
positive regulation of biosynthetic process GO:0009891 319 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
response to food GO:0032094 27 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
cell morphogenesis GO:0000902 142 0.011
cellular polysaccharide metabolic process GO:0044264 23 0.011
nucleotide metabolic process GO:0009117 279 0.011
polysaccharide metabolic process GO:0005976 25 0.011
response to alkaloid GO:0043279 132 0.011
response to nitrosative stress GO:0051409 2 0.011
positive regulation of cell communication GO:0010647 271 0.011
detection of chemical stimulus involved in sensory perception of taste GO:0050912 6 0.011
bile acid secretion GO:0032782 5 0.011
alditol metabolic process GO:0019400 4 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
cellular aldehyde metabolic process GO:0006081 11 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
cell cycle GO:0007049 101 0.011
urogenital system development GO:0001655 78 0.011
regulation of catecholamine secretion GO:0050433 32 0.011
cellular lipid catabolic process GO:0044242 37 0.011
pyridine nucleotide biosynthetic process GO:0019363 2 0.011
axis specification GO:0009798 4 0.011
energy reserve metabolic process GO:0006112 25 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.010
cellular component movement GO:0006928 248 0.010
nicotinamide nucleotide metabolic process GO:0046496 28 0.010
modified amino acid transport GO:0072337 12 0.010
dopamine transport GO:0015872 18 0.010
regulation of peptide transport GO:0090087 87 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
negative regulation of transport GO:0051051 136 0.010
protein homotrimerization GO:0070207 15 0.010
locomotion GO:0040011 237 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
positive regulation of synaptic transmission GO:0050806 62 0.010
proteoglycan metabolic process GO:0006029 3 0.010
benzene containing compound metabolic process GO:0042537 22 0.010
negative regulation of cell communication GO:0010648 158 0.010

Slc23a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
connective tissue disease DOID:65 0 0.024
musculoskeletal system disease DOID:17 0 0.024
disease of anatomical entity DOID:7 0 0.024
vascular disease DOID:178 0 0.015
cardiovascular system disease DOID:1287 0 0.015
endocrine system disease DOID:28 0 0.012