Rattus norvegicus

37 known processes

Slc7a11

solute carrier family 7 (cationic amino acid transporter, y+ system), member 11

Slc7a11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid transport GO:0046942 115 0.111
Yeast Rat
transmembrane transport GO:0055085 412 0.086
Yeast Rat
organic acid transport GO:0015849 116 0.084
Yeast Rat
brain development GO:0007420 247 0.077
nitrogen compound transport GO:0071705 229 0.077
Yeast Rat
anion transport GO:0006820 178 0.074
Yeast Rat
cellular response to oxygen containing compound GO:1901701 386 0.061
organic anion transport GO:0015711 132 0.059
Yeast Rat
cation transport GO:0006812 382 0.059
Yeast
ion transmembrane transport GO:0034220 365 0.058
Yeast Rat
oxoacid metabolic process GO:0043436 290 0.056
central nervous system development GO:0007417 311 0.055
cellular response to endogenous stimulus GO:0071495 377 0.054
homeostatic process GO:0042592 331 0.053
carboxylic acid metabolic process GO:0019752 289 0.051
response to nutrient levels GO:0031667 370 0.051
cell projection organization GO:0030030 302 0.051
intracellular signal transduction GO:0035556 314 0.050
regulation of cellular ketone metabolic process GO:0010565 27 0.048
catabolic process GO:0009056 351 0.047
regeneration GO:0031099 163 0.047
cellular ketone metabolic process GO:0042180 51 0.047
cell cell signaling GO:0007267 335 0.047
protein complex assembly GO:0006461 263 0.046
response to extracellular stimulus GO:0009991 380 0.045
response to estrogen GO:0043627 232 0.045
head development GO:0060322 247 0.044
protein complex subunit organization GO:0071822 302 0.043
apoptotic process GO:0006915 381 0.042
amino acid transmembrane transport GO:0003333 33 0.042
Yeast Rat
cellular amino acid metabolic process GO:0006520 107 0.042
regulation of cell proliferation GO:0042127 359 0.042
cell migration GO:0016477 197 0.042
anatomical structure morphogenesis GO:0009653 298 0.042
regulation of apoptotic process GO:0042981 335 0.041
amine metabolic process GO:0009308 38 0.040
protein complex biogenesis GO:0070271 263 0.040
positive regulation of multicellular organismal process GO:0051240 387 0.040
cellular component movement GO:0006928 248 0.040
locomotion GO:0040011 237 0.039
response to nutrient GO:0007584 248 0.039
response to estradiol GO:0032355 164 0.039
anion transmembrane transport GO:0098656 77 0.039
Yeast Rat
cellular component biogenesis GO:0044085 368 0.039
organic acid metabolic process GO:0006082 292 0.038
positive regulation of cell proliferation GO:0008284 249 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.038
cellular homeostasis GO:0019725 252 0.038
regulation of cellular amine metabolic process GO:0033238 8 0.038
programmed cell death GO:0012501 392 0.038
regulation of signal transduction GO:0009966 318 0.037
cellular response to stress GO:0033554 269 0.037
aging GO:0007568 241 0.037
cellular amine metabolic process GO:0044106 38 0.037
macromolecular complex subunit organization GO:0043933 339 0.037
chemical homeostasis GO:0048878 292 0.037
cellular response to organonitrogen compound GO:0071417 197 0.036
reproductive process GO:0022414 372 0.036
reproduction GO:0000003 245 0.036
single organism reproductive process GO:0044702 297 0.036
cardiovascular system development GO:0072358 134 0.036
regulation of programmed cell death GO:0043067 341 0.036
neuron development GO:0048666 286 0.035
neuron differentiation GO:0030182 368 0.035
cellular response to organic cyclic compound GO:0071407 202 0.035
protein phosphorylation GO:0006468 345 0.035
positive regulation of cell communication GO:0010647 271 0.035
neurological system process GO:0050877 219 0.035
positive regulation of transport GO:0051050 245 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
behavior GO:0007610 205 0.032
response to hypoxia GO:0001666 231 0.032
blood circulation GO:0008015 183 0.032
regulation of intracellular signal transduction GO:1902531 218 0.031
amino acid transport GO:0006865 70 0.031
Yeast Rat
metal ion transport GO:0030001 289 0.031
response to corticosteroid GO:0031960 235 0.031
positive regulation of developmental process GO:0051094 283 0.030
regulation of cell differentiation GO:0045595 320 0.030
regulation of phosphorylation GO:0042325 248 0.030
positive regulation of cell differentiation GO:0045597 217 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
regulation of cellular localization GO:0060341 263 0.030
positive regulation of cell death GO:0010942 184 0.029
response to glucocorticoid GO:0051384 223 0.029
oxidation reduction process GO:0055114 304 0.029
multi organism reproductive process GO:0044703 262 0.029
response to carbohydrate GO:0009743 183 0.028
response to wounding GO:0009611 254 0.028
multicellular organism reproduction GO:0032504 233 0.028
protein oligomerization GO:0051259 191 0.028
multicellular organismal reproductive process GO:0048609 233 0.027
macromolecular complex assembly GO:0065003 273 0.027
single organism biosynthetic process GO:0044711 342 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
response to toxic substance GO:0009636 133 0.027
Human
circulatory system development GO:0072359 134 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
localization of cell GO:0051674 202 0.026
cellular catabolic process GO:0044248 295 0.026
regulation of protein modification process GO:0031399 194 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
response to peptide hormone GO:0043434 278 0.025
response to monosaccharide GO:0034284 159 0.025
regulation of cellular component movement GO:0051270 150 0.025
organic substance catabolic process GO:1901575 316 0.024
positive regulation of gene expression GO:0010628 244 0.024
secretion GO:0046903 307 0.024
regulation of nervous system development GO:0051960 264 0.024
response to oxygen levels GO:0070482 265 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
circulatory system process GO:0003013 183 0.023
cell motility GO:0048870 202 0.023
organelle organization GO:0006996 266 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
regulation of neuron death GO:1901214 115 0.023
response to inorganic substance GO:0010035 377 0.023
response to acid chemical GO:0001101 222 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.022
regulation of ion transport GO:0043269 245 0.022
ras protein signal transduction GO:0007265 29 0.022
positive regulation of signaling GO:0023056 270 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
cellular chemical homeostasis GO:0055082 247 0.022
cellular component morphogenesis GO:0032989 155 0.022
neuron death GO:0070997 127 0.022
synaptic transmission GO:0007268 235 0.021
secretion by cell GO:0032940 248 0.021
response to decreased oxygen levels GO:0036293 237 0.021
regulation of anatomical structure size GO:0090066 135 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
cellular response to lipid GO:0071396 201 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
regulation of cell development GO:0060284 263 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
negative regulation of metabolic process GO:0009892 331 0.020
neuron projection development GO:0031175 273 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
mapk cascade GO:0000165 140 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
forebrain development GO:0030900 98 0.019
nucleic acid templated transcription GO:0097659 379 0.019
regulation of blood vessel size GO:0050880 89 0.019
response to glucose GO:0009749 136 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
response to peptide GO:1901652 292 0.019
response to hexose GO:0009746 144 0.019
carbohydrate metabolic process GO:0005975 130 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
regulation of cell projection organization GO:0031344 175 0.018
cell type specific apoptotic process GO:0097285 134 0.018
regulation of locomotion GO:0040012 148 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
gland development GO:0048732 155 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
calcium ion homeostasis GO:0055074 162 0.018
multi multicellular organism process GO:0044706 138 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
blood vessel development GO:0001568 69 0.018
regulation of molecular function GO:0065009 398 0.018
nucleotide metabolic process GO:0009117 279 0.018
cellular component assembly GO:0022607 360 0.017
positive regulation of signal transduction GO:0009967 175 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
single organism catabolic process GO:0044712 283 0.017
positive regulation of cell migration GO:0030335 96 0.017
single organism organelle organization GO:1902589 180 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
regulation of protein metabolic process GO:0051246 289 0.017
regulation of cellular component organization GO:0051128 368 0.017
macromolecule localization GO:0033036 252 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
cellular response to external stimulus GO:0071496 118 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
vascular process in circulatory system GO:0003018 96 0.017
regulation of neurogenesis GO:0050767 247 0.017
rna biosynthetic process GO:0032774 380 0.017
regulation of rna metabolic process GO:0051252 391 0.017
negative regulation of transport GO:0051051 136 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
monocarboxylic acid transport GO:0015718 52 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
reproductive structure development GO:0048608 128 0.016
regulation of neuron differentiation GO:0045664 208 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
response to ethanol GO:0045471 162 0.016
regulation of secretion GO:0051046 224 0.016
regulation of transcription dna templated GO:0006355 374 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
positive regulation of molecular function GO:0044093 230 0.016
muscle structure development GO:0061061 87 0.016
tissue development GO:0009888 252 0.016
positive regulation of ion transport GO:0043270 94 0.016
response to ketone GO:1901654 182 0.016
wound healing GO:0042060 122 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
cell projection morphogenesis GO:0048858 123 0.016
female pregnancy GO:0007565 122 0.016
regulation of mapk cascade GO:0043408 116 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
transcription dna templated GO:0006351 377 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
cell part morphogenesis GO:0032990 123 0.015
regulation of system process GO:0044057 208 0.015
response to retinoic acid GO:0032526 63 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
regulation of cell migration GO:0030334 128 0.015
negative regulation of cell communication GO:0010648 158 0.015
response to growth factor GO:0070848 189 0.015
protein transport GO:0015031 132 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
organ regeneration GO:0031100 101 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
single organism cellular localization GO:1902580 102 0.015
ion homeostasis GO:0050801 212 0.015
organic hydroxy compound transport GO:0015850 77 0.015
muscle system process GO:0003012 115 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
positive regulation of protein modification process GO:0031401 142 0.014
neural crest cell development GO:0014032 2 0.014
intracellular transport GO:0046907 185 0.014
amide transport GO:0042886 105 0.014
single organism intracellular transport GO:1902582 166 0.014
cellular cation homeostasis GO:0030003 180 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
neuron projection morphogenesis GO:0048812 122 0.014
regulation of tube size GO:0035150 89 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
cellular protein localization GO:0034613 122 0.014
defense response GO:0006952 194 0.014
cation homeostasis GO:0055080 195 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
metal ion homeostasis GO:0055065 186 0.014
cytoskeleton organization GO:0007010 111 0.014
negative regulation of cell death GO:0060548 229 0.014
muscle cell proliferation GO:0033002 84 0.014
regulation of cell motility GO:2000145 131 0.014
regulation of neuron projection development GO:0010975 161 0.014
regulation of hormone levels GO:0010817 187 0.013
rna metabolic process GO:0016070 406 0.013
sexual reproduction GO:0019953 148 0.013
response to alkaloid GO:0043279 132 0.013
cation transmembrane transport GO:0098655 263 0.013
Yeast
cellular response to growth factor stimulus GO:0071363 162 0.013
vasculature development GO:0001944 70 0.013
negative regulation of nervous system development GO:0051961 79 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
regulation of blood circulation GO:1903522 110 0.013
cellular response to acid chemical GO:0071229 75 0.013
regulation of secretion by cell GO:1903530 208 0.013
regulation of homeostatic process GO:0032844 101 0.013
positive regulation of cell development GO:0010720 176 0.013
heart morphogenesis GO:0003007 3 0.013
organophosphate metabolic process GO:0019637 370 0.013
regulation of synaptic transmission GO:0050804 141 0.013
aromatic compound catabolic process GO:0019439 168 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
negative regulation of developmental process GO:0051093 125 0.013
developmental growth GO:0048589 100 0.013
axon development GO:0061564 96 0.013
alpha amino acid metabolic process GO:1901605 71 0.013
immune system process GO:0002376 204 0.013
response to other organism GO:0051707 220 0.013
sex differentiation GO:0007548 113 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.012
regulation of metal ion transport GO:0010959 118 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
cognition GO:0050890 92 0.012
response to oxidative stress GO:0006979 186 0.012
negative regulation of signaling GO:0023057 157 0.012
rho protein signal transduction GO:0007266 11 0.012
neuron apoptotic process GO:0051402 88 0.012
peptidyl amino acid modification GO:0018193 126 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
gastrulation GO:0007369 2 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
response to cytokine GO:0034097 215 0.012
regulation of kinase activity GO:0043549 117 0.012
lipid metabolic process GO:0006629 283 0.012
axis specification GO:0009798 4 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of catalytic activity GO:0050790 304 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
signal release GO:0023061 145 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
positive regulation of nervous system development GO:0051962 178 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
neuron neuron synaptic transmission GO:0007270 60 0.012
purine containing compound metabolic process GO:0072521 253 0.012
regulation of transferase activity GO:0051338 123 0.012
growth GO:0040007 165 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
positive regulation of cell motility GO:2000147 97 0.012
hormone transport GO:0009914 121 0.012
rhythmic process GO:0048511 156 0.012
hexose metabolic process GO:0019318 58 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
multicellular organism growth GO:0035264 1 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
positive regulation of neuron death GO:1901216 43 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
cilium morphogenesis GO:0060271 2 0.011
regulation of response to stress GO:0080134 126 0.011
cellular response to alcohol GO:0097306 87 0.011
response to interleukin 1 GO:0070555 55 0.011
developmental process involved in reproduction GO:0003006 159 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
response to external biotic stimulus GO:0043207 221 0.011
regulation of body fluid levels GO:0050878 90 0.011
dicarboxylic acid transport GO:0006835 34 0.011
positive regulation of transferase activity GO:0051347 81 0.011
response to mechanical stimulus GO:0009612 134 0.011
peptide transport GO:0015833 97 0.011
response to lipopolysaccharide GO:0032496 191 0.011
vasoconstriction GO:0042310 54 0.011
angiogenesis GO:0001525 53 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
inflammatory response GO:0006954 150 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cellular response to peptide GO:1901653 133 0.011
regulation of protein transport GO:0051223 68 0.011
response to purine containing compound GO:0014074 126 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
regulation of vasculature development GO:1901342 44 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
proteolysis GO:0006508 175 0.010
reproductive system development GO:0061458 128 0.010
establishment of protein localization GO:0045184 141 0.010
response to vitamin GO:0033273 131 0.010
salivary gland morphogenesis GO:0007435 1 0.010
regulation of angiogenesis GO:0045765 39 0.010
protein localization GO:0008104 191 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
regulation of response to external stimulus GO:0032101 106 0.010
peptidyl tyrosine modification GO:0018212 72 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
biological adhesion GO:0022610 110 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
cell activation GO:0001775 97 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
chromosome segregation GO:0007059 2 0.010
calcium ion transport GO:0006816 131 0.010
axonogenesis GO:0007409 71 0.010
hepaticobiliary system development GO:0061008 90 0.010
cytokine production GO:0001816 61 0.010
cellular ion homeostasis GO:0006873 184 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
regulation of blood pressure GO:0008217 83 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
organophosphate biosynthetic process GO:0090407 143 0.010

Slc7a11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.020
disease of anatomical entity DOID:7 0 0.020
disease of metabolism DOID:0014667 0 0.011
central nervous system disease DOID:331 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
disease of cellular proliferation DOID:14566 0 0.011