Rattus norvegicus

24 known processes

Slco1a4

solute carrier organic anion transporter family, member 1a4

(Aliases: Slc21a5,Oatp2)

Slco1a4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lauric acid metabolic process GO:0048252 4 0.261
exogenous drug catabolic process GO:0042738 1 0.182
cellular lipid metabolic process GO:0044255 208 0.180
drug catabolic process GO:0042737 1 0.176
nitrogen compound transport GO:0071705 229 0.167
organic anion transport GO:0015711 132 0.151
alkaloid metabolic process GO:0009820 3 0.149
response to metal ion GO:0010038 253 0.137
regulation of amino acid transport GO:0051955 25 0.120
response to triglyceride GO:0034014 3 0.117
drug transmembrane transport GO:0006855 13 0.114
response to testosterone GO:0033574 55 0.110
choline transport GO:0015871 4 0.108
behavior GO:0007610 205 0.102
halogenated hydrocarbon metabolic process GO:0042197 4 0.091
monocarboxylic acid metabolic process GO:0032787 152 0.091
organonitrogen compound biosynthetic process GO:1901566 167 0.086
oxoacid metabolic process GO:0043436 290 0.086
carboxylic acid metabolic process GO:0019752 289 0.085
amino acid transmembrane transport GO:0003333 33 0.084
lipid metabolic process GO:0006629 283 0.083
drug metabolic process GO:0017144 11 0.083
transmembrane transport GO:0055085 412 0.079
macromolecule localization GO:0033036 252 0.076
response to transition metal nanoparticle GO:1990267 122 0.073
organic acid metabolic process GO:0006082 292 0.073
fluorene metabolic process GO:0018917 1 0.072
extracellular matrix constituent secretion GO:0070278 4 0.071
cellular catabolic process GO:0044248 295 0.068
glycerolipid metabolic process GO:0046486 67 0.068
monocarboxylic acid transport GO:0015718 52 0.067
response to cesium ion GO:0010164 2 0.064
organic hydroxy compound metabolic process GO:1901615 115 0.061
positive regulation of transport GO:0051050 245 0.059
response to toxic substance GO:0009636 133 0.058
response to acid chemical GO:0001101 222 0.055
single organism biosynthetic process GO:0044711 342 0.054
amine metabolic process GO:0009308 38 0.052
regulation of secretion GO:0051046 224 0.052
oligopeptide transport GO:0006857 4 0.052
amino acid transport GO:0006865 70 0.052
organic acid transport GO:0015849 116 0.051
long chain fatty acid metabolic process GO:0001676 32 0.051
positive regulation of multicellular organismal process GO:0051240 387 0.049
regulation of cellular component organization GO:0051128 368 0.049
toxin metabolic process GO:0009404 9 0.048
carboxylic acid transport GO:0046942 115 0.047
chlorinated hydrocarbon metabolic process GO:0042196 4 0.047
regulation of secretion by cell GO:1903530 208 0.047
toxin catabolic process GO:0009407 1 0.046
response to xenobiotic stimulus GO:0009410 23 0.046
epoxygenase p450 pathway GO:0019373 1 0.046
response to ketone GO:1901654 182 0.046
cellular amine metabolic process GO:0044106 38 0.046
trichloroethylene metabolic process GO:0018979 1 0.043
multi organism reproductive process GO:0044703 262 0.043
ion transmembrane transport GO:0034220 365 0.042
anion transmembrane transport GO:0098656 77 0.042
response to inorganic substance GO:0010035 377 0.041
response to other organism GO:0051707 220 0.040
oxidative demethylation GO:0070989 2 0.038
blood circulation GO:0008015 183 0.038
cellular homeostasis GO:0019725 252 0.037
dicarboxylic acid transport GO:0006835 34 0.035
reproductive process GO:0022414 372 0.035
benzene containing compound metabolic process GO:0042537 22 0.035
liver development GO:0001889 90 0.034
sulfur compound transport GO:0072348 8 0.034
cellular amino acid metabolic process GO:0006520 107 0.034
regulation of ion transport GO:0043269 245 0.034
vitamin transport GO:0051180 14 0.033
linoleic acid metabolic process GO:0043651 4 0.033
homeostatic process GO:0042592 331 0.033
synaptic transmission GO:0007268 235 0.032
cation transport GO:0006812 382 0.032
small molecule biosynthetic process GO:0044283 124 0.032
negative regulation of developmental process GO:0051093 125 0.031
amide transport GO:0042886 105 0.031
chemical homeostasis GO:0048878 292 0.030
response to peptide hormone GO:0043434 278 0.030
organic cyclic compound catabolic process GO:1901361 175 0.030
cellular response to hormone stimulus GO:0032870 247 0.030
protein localization GO:0008104 191 0.030
anion transport GO:0006820 178 0.030
regulation of gamma aminobutyric acid secretion GO:0014052 6 0.029
response to hypoxia GO:0001666 231 0.029
calcitriol biosynthetic process from calciol GO:0036378 2 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
modified amino acid transport GO:0072337 12 0.029
insecticide metabolic process GO:0017143 4 0.028
terpenoid metabolic process GO:0006721 37 0.028
fatty acid metabolic process GO:0006631 99 0.028
macromolecular complex assembly GO:0065003 273 0.028
negative regulation of serine type peptidase activity GO:1902572 1 0.028
response to decreased oxygen levels GO:0036293 237 0.028
secretion by cell GO:0032940 248 0.028
catabolic process GO:0009056 351 0.027
naphthalene metabolic process GO:0018931 2 0.027
response to extracellular stimulus GO:0009991 380 0.027
organonitrogen compound catabolic process GO:1901565 179 0.027
cellular sodium ion homeostasis GO:0006883 4 0.027
single organism behavior GO:0044708 130 0.026
positive regulation of secretion by cell GO:1903532 128 0.026
nicotine metabolic process GO:0018933 1 0.026
dopamine metabolic process GO:0042417 12 0.026
vesicle mediated transport GO:0016192 181 0.026
regulation of tube size GO:0035150 89 0.026
response to sulfur dioxide GO:0010477 3 0.026
small molecule catabolic process GO:0044282 59 0.025
regulation of serine type peptidase activity GO:1902571 1 0.025
alcohol metabolic process GO:0006066 77 0.025
multicellular organism growth GO:0035264 1 0.024
cellular ion homeostasis GO:0006873 184 0.024
angiotensin mediated drinking behavior GO:0003051 2 0.024
regulation of apoptotic process GO:0042981 335 0.024
secretion GO:0046903 307 0.024
response to external biotic stimulus GO:0043207 221 0.024
isoprenoid metabolic process GO:0006720 45 0.024
neurological system process GO:0050877 219 0.024
cellular component assembly GO:0022607 360 0.024
regulation of cellular localization GO:0060341 263 0.023
xenobiotic metabolic process GO:0006805 19 0.023
response to ethanol GO:0045471 162 0.023
head development GO:0060322 247 0.023
response to oxidative stress GO:0006979 186 0.023
negative regulation of serine type endopeptidase activity GO:1900004 1 0.022
response to peptide GO:1901652 292 0.022
circulatory system process GO:0003013 183 0.022
regulation of programmed cell death GO:0043067 341 0.022
response to vitamin b6 GO:0034516 1 0.022
cellular biogenic amine catabolic process GO:0042402 9 0.022
cellular chemical homeostasis GO:0055082 247 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
cytolysis GO:0019835 4 0.021
regulation of nervous system development GO:0051960 264 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
positive regulation of secretion GO:0051047 140 0.021
response to glucocorticoid GO:0051384 223 0.021
vasoconstriction GO:0042310 54 0.021
cellular response to lipid GO:0071396 201 0.021
response to ddt GO:0046680 1 0.021
amine catabolic process GO:0009310 9 0.020
organelle organization GO:0006996 266 0.020
organic hydroxy compound biosynthetic process GO:1901617 51 0.020
response to insecticide GO:0017085 21 0.020
intestinal absorption GO:0050892 3 0.020
regulation of neurotransmitter levels GO:0001505 42 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
negative regulation of nervous system development GO:0051961 79 0.020
cellular cation homeostasis GO:0030003 180 0.020
response to ionizing radiation GO:0010212 59 0.020
regulation of blood pressure GO:0008217 83 0.020
protein oligomerization GO:0051259 191 0.019
response to oxygen levels GO:0070482 265 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
metal ion transport GO:0030001 289 0.019
single organism organelle organization GO:1902589 180 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
cation homeostasis GO:0055080 195 0.019
cellular component biogenesis GO:0044085 368 0.019
phenylpropanoid metabolic process GO:0009698 5 0.019
phenol containing compound biosynthetic process GO:0046189 9 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
glutathione transport GO:0034635 2 0.018
regeneration GO:0031099 163 0.018
unsaturated fatty acid metabolic process GO:0033559 39 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
neuron differentiation GO:0030182 368 0.018
regulation of hormone levels GO:0010817 187 0.017
negative regulation of metabolic process GO:0009892 331 0.017
hormone transport GO:0009914 121 0.017
lipid biosynthetic process GO:0008610 128 0.017
positive regulation of nervous system development GO:0051962 178 0.017
regulation of amine transport GO:0051952 54 0.017
response to estrogen GO:0043627 232 0.017
regulation of anion transport GO:0044070 43 0.017
protein transport GO:0015031 132 0.017
cerebellar granule cell precursor proliferation GO:0021930 1 0.017
regulation of serine type endopeptidase activity GO:1900003 1 0.017
lipid localization GO:0010876 62 0.017
secondary metabolite catabolic process GO:0090487 1 0.017
fatty acid derivative metabolic process GO:1901568 38 0.017
central nervous system development GO:0007417 311 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.016
apoptotic process GO:0006915 381 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
organic substance catabolic process GO:1901575 316 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
response to fatty acid GO:0070542 65 0.016
metanephric comma shaped body morphogenesis GO:0072278 2 0.016
regulation of immune response GO:0050776 55 0.016
multicellular organism reproduction GO:0032504 233 0.016
regulation of organic acid transport GO:0032890 35 0.016
defense response to gram negative bacterium GO:0050829 3 0.016
regulation of phosphate metabolic process GO:0019220 349 0.015
cellular ketone metabolic process GO:0042180 51 0.015
organic hydroxy compound transport GO:0015850 77 0.015
cellular biogenic amine metabolic process GO:0006576 30 0.015
diterpenoid metabolic process GO:0016101 33 0.015
regulation of neurogenesis GO:0050767 247 0.015
cell proliferation in external granule layer GO:0021924 1 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
drug transport GO:0015893 18 0.015
beta alanine metabolic process GO:0019482 3 0.015
positive regulation of developmental process GO:0051094 283 0.015
transcription dna templated GO:0006351 377 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
brain development GO:0007420 247 0.015
carboxylic acid biosynthetic process GO:0046394 83 0.015
bile acid and bile salt transport GO:0015721 12 0.014
hepaticobiliary system development GO:0061008 90 0.014
response to mercury ion GO:0046689 15 0.014
organophosphate metabolic process GO:0019637 370 0.014
immune system process GO:0002376 204 0.014
heterocycle catabolic process GO:0046700 167 0.014
response to vitamin d GO:0033280 34 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
catechol containing compound metabolic process GO:0009712 19 0.014
negative regulation of cell communication GO:0010648 158 0.014
reproduction GO:0000003 245 0.014
medium chain fatty acid metabolic process GO:0051791 5 0.014
response to calcium ion GO:0051592 59 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
renin angiotensin regulation of aldosterone production GO:0002018 3 0.014
pyridine containing compound metabolic process GO:0072524 32 0.013
response to lead ion GO:0010288 33 0.013
regulation of immune system process GO:0002682 123 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
organic acid catabolic process GO:0016054 49 0.013
glycoside transport GO:1901656 2 0.013
response to nutrient levels GO:0031667 370 0.013
regulation of extracellular matrix constituent secretion GO:0003330 2 0.013
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.013
cellular response to stress GO:0033554 269 0.013
regulation of blood vessel size GO:0050880 89 0.013
antibiotic transport GO:0042891 2 0.013
intracellular transport GO:0046907 185 0.013
triglyceride metabolic process GO:0006641 21 0.013
secretion by tissue GO:0032941 37 0.013
response to methanol GO:0033986 1 0.013
circulatory system development GO:0072359 134 0.012
protein complex assembly GO:0006461 263 0.012
rna biosynthetic process GO:0032774 380 0.012
cellular response to xenobiotic stimulus GO:0071466 19 0.012
regulation of cell differentiation GO:0045595 320 0.012
response to purine containing compound GO:0014074 126 0.012
gland development GO:0048732 155 0.012
transmission of nerve impulse GO:0019226 42 0.012
localization of cell GO:0051674 202 0.012
regulation of anatomical structure size GO:0090066 135 0.012
tonic smooth muscle contraction GO:0014820 4 0.012
oxidation reduction process GO:0055114 304 0.012
protein complex biogenesis GO:0070271 263 0.012
regulation of protein metabolic process GO:0051246 289 0.012
glycogen metabolic process GO:0005977 23 0.012
organic cation transport GO:0015695 11 0.012
odontogenesis GO:0042476 32 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
aromatic amino acid family catabolic process GO:0009074 7 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
organic acid biosynthetic process GO:0016053 83 0.012
tripeptide transport GO:0042939 2 0.012
sexual reproduction GO:0019953 148 0.012
response to carbohydrate GO:0009743 183 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
nucleotide metabolic process GO:0009117 279 0.011
indole containing compound metabolic process GO:0042430 11 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
protein complex subunit organization GO:0071822 302 0.011
aromatic amino acid family metabolic process GO:0009072 9 0.011
catechol containing compound biosynthetic process GO:0009713 9 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
response to alkaloid GO:0043279 132 0.011
positive regulation of blood circulation GO:1903524 65 0.011
regulation of immunoglobulin production GO:0002637 4 0.011
indolalkylamine metabolic process GO:0006586 5 0.011
positive regulation of signaling GO:0023056 270 0.011
cellular hormone metabolic process GO:0034754 49 0.011
positive regulation of long term synaptic potentiation GO:1900273 4 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
lipid transport GO:0006869 61 0.011
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.011
carbohydrate metabolic process GO:0005975 130 0.011
growth GO:0040007 165 0.011
response to cadmium ion GO:0046686 35 0.011
negative regulation of protein metabolic process GO:0051248 114 0.010
gamma aminobutyric acid secretion GO:0014051 6 0.010
negative regulation of molecular function GO:0044092 133 0.010
positive regulation of extracellular matrix organization GO:1903055 4 0.010
cellular response to corticosteroid stimulus GO:0071384 69 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
positive regulation of amine transport GO:0051954 26 0.010
naphthalene containing compound metabolic process GO:0090420 2 0.010
single organism catabolic process GO:0044712 283 0.010
protein homooligomerization GO:0051260 91 0.010
developmental process involved in reproduction GO:0003006 159 0.010
neurotransmitter uptake GO:0001504 3 0.010

Slco1a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.132
vascular disease DOID:178 0 0.132
cardiovascular system disease DOID:1287 0 0.132
hypertension DOID:10763 0 0.044
artery disease DOID:0050828 0 0.044
essential hypertension DOID:10825 0 0.015
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010