Rattus norvegicus

47 known processes

Slco1a5

solute carrier organic anion transporter family, member 1a5

(Aliases: Slc21a7,OATP-3,Slco1a2,Oatp3)

Slco1a5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 365 0.187
cation transport GO:0006812 382 0.182
head development GO:0060322 247 0.180
divalent inorganic cation homeostasis GO:0072507 165 0.171
nitrogen compound transport GO:0071705 229 0.171
inorganic ion transmembrane transport GO:0098660 229 0.160
potassium ion transport GO:0006813 97 0.157
metal ion transport GO:0030001 289 0.140
monovalent inorganic cation transport GO:0015672 172 0.134
brain development GO:0007420 247 0.131
cellular ion homeostasis GO:0006873 184 0.108
central nervous system development GO:0007417 311 0.105
homeostatic process GO:0042592 331 0.098
anion transport GO:0006820 178 0.096
cellular homeostasis GO:0019725 252 0.089
cellular cation homeostasis GO:0030003 180 0.089
transmembrane transport GO:0055085 412 0.088
immune system process GO:0002376 204 0.085
cation transmembrane transport GO:0098655 263 0.082
cation homeostasis GO:0055080 195 0.074
calcium ion homeostasis GO:0055074 162 0.072
cellular amine metabolic process GO:0044106 38 0.071
positive regulation of multicellular organismal process GO:0051240 387 0.071
cellular chemical homeostasis GO:0055082 247 0.069
regulation of membrane potential GO:0042391 110 0.068
chemical homeostasis GO:0048878 292 0.067
metal ion homeostasis GO:0055065 186 0.066
cellular component biogenesis GO:0044085 368 0.063
detection of stimulus GO:0051606 24 0.062
inorganic cation transmembrane transport GO:0098662 202 0.060
response to cytokine GO:0034097 215 0.054
Rat
oxoacid metabolic process GO:0043436 290 0.052
Rat
anion transmembrane transport GO:0098656 77 0.050
regulation of intracellular signal transduction GO:1902531 218 0.050
immune system development GO:0002520 41 0.047
neuron development GO:0048666 286 0.047
cellular response to histamine GO:0071420 3 0.046
positive regulation of cell migration GO:0030335 96 0.045
regulation of secretion by cell GO:1903530 208 0.045
defense response GO:0006952 194 0.045
amine metabolic process GO:0009308 38 0.044
response to growth factor GO:0070848 189 0.044
reproductive process GO:0022414 372 0.044
eye morphogenesis GO:0048592 4 0.043
acute inflammatory response GO:0002526 58 0.041
intracellular signal transduction GO:0035556 314 0.041
coumarin catabolic process GO:0046226 3 0.041
single organism biosynthetic process GO:0044711 342 0.040
inflammatory response GO:0006954 150 0.040
reproduction GO:0000003 245 0.040
halogenated hydrocarbon metabolic process GO:0042197 4 0.039
cellular protein localization GO:0034613 122 0.039
divalent metal ion transport GO:0070838 132 0.037
regulation of immune system process GO:0002682 123 0.037
response to oxidative stress GO:0006979 186 0.037
organic acid metabolic process GO:0006082 292 0.036
Rat
organelle organization GO:0006996 266 0.035
regulation of protein metabolic process GO:0051246 289 0.035
blood circulation GO:0008015 183 0.035
ion homeostasis GO:0050801 212 0.034
cellular lipid metabolic process GO:0044255 208 0.034
positive regulation of phosphorylation GO:0042327 177 0.033
cellular response to stress GO:0033554 269 0.032
cellular metal ion homeostasis GO:0006875 172 0.032
regulation of signal transduction GO:0009966 318 0.031
negative regulation of transport GO:0051051 136 0.031
secretion by cell GO:0032940 248 0.031
protein localization GO:0008104 191 0.031
multi organism reproductive process GO:0044703 262 0.031
chlorinated hydrocarbon metabolic process GO:0042196 4 0.030
response to mechanical stimulus GO:0009612 134 0.030
macromolecular complex assembly GO:0065003 273 0.030
positive regulation of protein transport GO:0051222 41 0.030
sodium ion transport GO:0006814 82 0.029
hematopoietic or lymphoid organ development GO:0048534 36 0.029
response to external biotic stimulus GO:0043207 221 0.029
Rat
neurological system process GO:0050877 219 0.028
cell cell signaling GO:0007267 335 0.028
regulation of saliva secretion GO:0046877 3 0.028
synaptic transmission glycinergic GO:0060012 2 0.028
positive regulation of cellular component movement GO:0051272 102 0.028
response to ketone GO:1901654 182 0.028
regulation of potassium ion transport GO:0043266 29 0.027
forebrain development GO:0030900 98 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
regulation of ion transport GO:0043269 245 0.027
striated muscle contraction GO:0006941 44 0.027
regeneration GO:0031099 163 0.026
monocarboxylic acid metabolic process GO:0032787 152 0.026
glycerolipid metabolic process GO:0046486 67 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
lipid metabolic process GO:0006629 283 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
regulation of tube size GO:0035150 89 0.025
protein complex assembly GO:0006461 263 0.025
xenobiotic catabolic process GO:0042178 7 0.025
synaptic transmission gabaergic GO:0051932 22 0.025
eosinophil migration GO:0072677 3 0.025
positive regulation of transport GO:0051050 245 0.024
protein phosphorylation GO:0006468 345 0.024
single organism reproductive process GO:0044702 297 0.024
protein heterooligomerization GO:0051291 89 0.024
regulation of metal ion transport GO:0010959 118 0.024
cellular component assembly GO:0022607 360 0.024
protein oligomerization GO:0051259 191 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
amino acid transport GO:0006865 70 0.023
response to nutrient levels GO:0031667 370 0.023
multicellular organismal homeostasis GO:0048871 49 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
neuron neuron synaptic transmission GO:0007270 60 0.023
cellular response to external stimulus GO:0071496 118 0.023
carboxylic acid transport GO:0046942 115 0.023
response to peptide hormone GO:0043434 278 0.023
Rat
regulation of cellular localization GO:0060341 263 0.023
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.022
regulation of sodium ion transport GO:0002028 21 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.022
t cell chemotaxis GO:0010818 2 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
neuron differentiation GO:0030182 368 0.022
hormone metabolic process GO:0042445 69 0.022
Rat
angiogenesis GO:0001525 53 0.022
protein complex subunit organization GO:0071822 302 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
Rat
oligopeptide transport GO:0006857 4 0.022
Rat
phospholipid metabolic process GO:0006644 61 0.022
regulation of cell differentiation GO:0045595 320 0.021
signal transduction by phosphorylation GO:0023014 144 0.021
regulation of molecular function GO:0065009 398 0.021
involuntary skeletal muscle contraction GO:0003011 2 0.021
protein transport GO:0015031 132 0.021
positive regulation of cell death GO:0010942 184 0.021
regulation of transmembrane transport GO:0034762 122 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
lymphocyte migration GO:0072676 3 0.020
purine containing compound metabolic process GO:0072521 253 0.020
response to toxic substance GO:0009636 133 0.020
Rat
amide transport GO:0042886 105 0.020
Rat
cellular response to xenobiotic stimulus GO:0071466 19 0.020
positive regulation of dna metabolic process GO:0051054 39 0.020
regulation of transporter activity GO:0032409 50 0.020
protein secretion GO:0009306 34 0.020
mapk cascade GO:0000165 140 0.020
glucose homeostasis GO:0042593 75 0.020
heart morphogenesis GO:0003007 3 0.020
cellular component movement GO:0006928 248 0.020
organic anion transport GO:0015711 132 0.020
multicellular organism reproduction GO:0032504 233 0.019
glycerophospholipid metabolic process GO:0006650 47 0.019
regulation of phosphorylation GO:0042325 248 0.019
synaptic transmission GO:0007268 235 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
organ regeneration GO:0031100 101 0.019
regulation of immunoglobulin production GO:0002637 4 0.019
secretion GO:0046903 307 0.019
regulation of cell proliferation GO:0042127 359 0.019
dephosphorylation GO:0016311 98 0.019
cytosolic calcium ion homeostasis GO:0051480 140 0.018
dopamine metabolic process GO:0042417 12 0.018
regulation of establishment of protein localization GO:0070201 69 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
response to other organism GO:0051707 220 0.018
Rat
cell activation GO:0001775 97 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
cardiac muscle contraction GO:0060048 27 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
behavior GO:0007610 205 0.017
single organism catabolic process GO:0044712 283 0.017
lipid transport GO:0006869 61 0.017
liver development GO:0001889 90 0.017
Rat
regulation of mapk cascade GO:0043408 116 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
response to ionizing radiation GO:0010212 59 0.017
response to histamine GO:0034776 3 0.017
positive regulation of lymphocyte proliferation GO:0050671 20 0.017
synapse assembly GO:0007416 29 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
regulation of protein localization GO:0032880 81 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.016
lipid biosynthetic process GO:0008610 128 0.016
regulation of secretion GO:0051046 224 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
anterior posterior pattern specification GO:0009952 1 0.016
t cell extravasation GO:0072683 1 0.016
positive regulation of long term synaptic potentiation GO:1900273 4 0.016
response to xenobiotic stimulus GO:0009410 23 0.016
response to metal ion GO:0010038 253 0.016
positive regulation of immunoglobulin production GO:0002639 4 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
response to ammonium ion GO:0060359 71 0.016
response to hexose GO:0009746 144 0.016
phosphatidylinositol dephosphorylation GO:0046856 4 0.016
t cell migration GO:0072678 2 0.016
regulation of cytokine biosynthetic process GO:0042035 3 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
positive regulation of lymphocyte activation GO:0051251 25 0.016
calcium ion transport GO:0006816 131 0.016
response to monosaccharide GO:0034284 159 0.016
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
regulation of ion transmembrane transport GO:0034765 121 0.015
telencephalon development GO:0021537 62 0.015
response to cold GO:0009409 29 0.015
endothelial cell morphogenesis GO:0001886 1 0.015
response to alkaloid GO:0043279 132 0.015
positive regulation of locomotion GO:0040017 102 0.015
response to radiation GO:0009314 137 0.015
negative regulation of vesicle fusion GO:0031339 2 0.015
potassium ion transmembrane transport GO:0071805 71 0.015
positive regulation of cell development GO:0010720 176 0.015
eating behavior GO:0042755 21 0.015
regulation of response to external stimulus GO:0032101 106 0.015
regulation of protein transport GO:0051223 68 0.015
negative regulation of long term synaptic potentiation GO:1900272 1 0.015
neurotransmitter gated ion channel clustering GO:0072578 3 0.015
negative regulation of chronic inflammatory response GO:0002677 2 0.015
sensory perception GO:0007600 101 0.015
positive regulation of mononuclear cell proliferation GO:0032946 20 0.014
negative regulation of ion transport GO:0043271 51 0.014
organophosphate metabolic process GO:0019637 370 0.014
muscle contraction GO:0006936 88 0.014
acute phase response GO:0006953 20 0.014
divalent inorganic cation transport GO:0072511 134 0.014
negative regulation of molecular function GO:0044092 133 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
positive regulation of secretion GO:0051047 140 0.014
positive regulation of protein secretion GO:0050714 19 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
regulation of homeostatic process GO:0032844 101 0.014
blood vessel development GO:0001568 69 0.014
cell cycle GO:0007049 101 0.014
negative regulation of cell communication GO:0010648 158 0.014
blood vessel morphogenesis GO:0048514 58 0.014
saliva secretion GO:0046541 3 0.014
tissue development GO:0009888 252 0.014
lymphocyte proliferation GO:0046651 29 0.014
cellular biogenic amine metabolic process GO:0006576 30 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
retina morphogenesis in camera type eye GO:0060042 1 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.013
carboxylic acid catabolic process GO:0046395 49 0.013
retina development in camera type eye GO:0060041 27 0.013
regulation of cardiac muscle contraction GO:0055117 17 0.013
xenobiotic metabolic process GO:0006805 19 0.013
benzene containing compound metabolic process GO:0042537 22 0.013
pallium development GO:0021543 42 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.013
detection of temperature stimulus involved in sensory perception of pain GO:0050965 4 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
response to nutrient GO:0007584 248 0.013
endomembrane system organization GO:0010256 48 0.013
angioblast cell migration GO:0035476 1 0.013
response to extracellular stimulus GO:0009991 380 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
regulation of dna metabolic process GO:0051052 60 0.013
diaphragm contraction GO:0002086 2 0.013
response to wounding GO:0009611 254 0.013
regulation of homotypic cell cell adhesion GO:0034110 4 0.013
interleukin 1 biosynthetic process GO:0042222 1 0.013
regulation of lymphocyte chemotaxis GO:1901623 1 0.012
negative regulation of developmental process GO:0051093 125 0.012
positive regulation of developmental process GO:0051094 283 0.012
sensory organ development GO:0007423 74 0.012
regulation of synaptic transmission glutamatergic GO:0051966 26 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
aging GO:0007568 241 0.012
sexual reproduction GO:0019953 148 0.012
lymphocyte chemotaxis GO:0048247 3 0.012
regulation of angiogenesis GO:0045765 39 0.012
positive regulation of t cell migration GO:2000406 1 0.012
rhythmic process GO:0048511 156 0.012
regulation of cell development GO:0060284 263 0.012
male gamete generation GO:0048232 99 0.012
muscle system process GO:0003012 115 0.012
single organism organelle organization GO:1902589 180 0.012
male gonad development GO:0008584 59 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
cellular response to tumor necrosis factor GO:0071356 46 0.012
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
cellular potassium ion transport GO:0071804 72 0.012
spermatogenesis GO:0007283 99 0.012
antibiotic transport GO:0042891 2 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
cell cycle process GO:0022402 57 0.012
rho protein signal transduction GO:0007266 11 0.012
embryonic skeletal system development GO:0048706 3 0.012
urinary tract smooth muscle contraction GO:0014848 4 0.012
positive regulation of isotype switching GO:0045830 1 0.012
cellular response to growth factor stimulus GO:0071363 162 0.011
regulation of platelet activation GO:0010543 2 0.011
membrane depolarization GO:0051899 32 0.011
cellular ketone metabolic process GO:0042180 51 0.011
lymphocyte activation GO:0046649 43 0.011
cd8 positive alpha beta t cell extravasation GO:0035697 0 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.011
response to transforming growth factor beta GO:0071559 46 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
cell projection organization GO:0030030 302 0.011
regulation of protein secretion GO:0050708 28 0.011
regulation of synaptic transmission GO:0050804 141 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.011
vesicle organization GO:0016050 29 0.011
circadian rhythm GO:0007623 88 0.011
response to inorganic substance GO:0010035 377 0.011
response to ethanol GO:0045471 162 0.011
regulation of lymphocyte migration GO:2000401 1 0.011
vascular process in circulatory system GO:0003018 96 0.011
single organism membrane organization GO:0044802 74 0.011
cellular macromolecule localization GO:0070727 122 0.011
neurotransmitter transport GO:0006836 42 0.011
response to decreased oxygen levels GO:0036293 237 0.011
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
sensory perception of pain GO:0019233 73 0.011
response to corticosteroid GO:0031960 235 0.011
Rat
membrane organization GO:0061024 94 0.011
response to tumor necrosis factor GO:0034612 56 0.011
hormone transport GO:0009914 121 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.010
circulatory system process GO:0003013 183 0.010
positive regulation of immune system process GO:0002684 90 0.010
positive regulation of protein modification process GO:0031401 142 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
cellular response to nutrient levels GO:0031669 60 0.010
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.010
gamete generation GO:0007276 124 0.010
regulation of striated muscle contraction GO:0006942 21 0.010
camera type eye development GO:0043010 48 0.010
cofactor metabolic process GO:0051186 95 0.010
regulation of nervous system development GO:0051960 264 0.010
cellular response to glucose stimulus GO:0071333 65 0.010
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.010
eosinophil chemotaxis GO:0048245 3 0.010
hemopoiesis GO:0030097 34 0.010

Slco1a5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.045
inherited metabolic disorder DOID:655 0 0.045
sensory system disease DOID:0050155 0 0.019
disease of anatomical entity DOID:7 0 0.019
eye and adnexa disease DOID:1492 0 0.019
nervous system disease DOID:863 0 0.019
eye disease DOID:5614 0 0.019
retinal disease DOID:5679 0 0.015
retinal degeneration DOID:8466 0 0.015