Rattus norvegicus

0 known processes

Slfn8

schlafen 8

Slfn8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.155
positive regulation of cellular biosynthetic process GO:0031328 295 0.122
cellular response to hormone stimulus GO:0032870 247 0.119
immune system process GO:0002376 204 0.117
Human
response to peptide GO:1901652 292 0.117
intracellular signal transduction GO:0035556 314 0.108
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.108
regulation of molecular function GO:0065009 398 0.103
neuron death GO:0070997 127 0.093
positive regulation of rna metabolic process GO:0051254 203 0.088
organophosphate metabolic process GO:0019637 370 0.087
positive regulation of cell death GO:0010942 184 0.086
response to oxidative stress GO:0006979 186 0.086
positive regulation of biosynthetic process GO:0009891 319 0.085
regulation of phosphorus metabolic process GO:0051174 349 0.084
regulation of neuron death GO:1901214 115 0.083
regulation of rna metabolic process GO:0051252 391 0.080
cellular response to endogenous stimulus GO:0071495 377 0.079
regulation of neuron apoptotic process GO:0043523 83 0.077
regulation of signal transduction GO:0009966 318 0.074
regulation of rna biosynthetic process GO:2001141 381 0.074
protein phosphorylation GO:0006468 345 0.073
response to peptide hormone GO:0043434 278 0.073
cellular response to oxygen containing compound GO:1901701 386 0.072
regulation of immune system process GO:0002682 123 0.071
nucleobase containing small molecule metabolic process GO:0055086 316 0.070
programmed cell death GO:0012501 392 0.070
regulation of phosphate metabolic process GO:0019220 349 0.069
single organism intracellular transport GO:1902582 166 0.068
neuron apoptotic process GO:0051402 88 0.065
cellular response to peptide GO:1901653 133 0.064
response to inorganic substance GO:0010035 377 0.063
regulation of cellular protein metabolic process GO:0032268 267 0.061
carbohydrate derivative metabolic process GO:1901135 346 0.061
regulation of nucleic acid templated transcription GO:1903506 380 0.060
regulation of cellular component organization GO:0051128 368 0.060
nucleotide metabolic process GO:0009117 279 0.057
cellular response to nitrogen compound GO:1901699 210 0.057
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.056
positive regulation of phosphate metabolic process GO:0045937 262 0.054
ribose phosphate metabolic process GO:0019693 235 0.054
protein heterooligomerization GO:0051291 89 0.054
organic substance catabolic process GO:1901575 316 0.051
anatomical structure morphogenesis GO:0009653 298 0.051
response to hydrogen peroxide GO:0042542 89 0.050
regulation of lymphocyte migration GO:2000401 1 0.049
nucleoside triphosphate catabolic process GO:0009143 123 0.048
protein localization GO:0008104 191 0.048
purine ribonucleotide metabolic process GO:0009150 227 0.047
cellular response to organonitrogen compound GO:0071417 197 0.047
positive regulation of gene expression GO:0010628 244 0.046
ribonucleotide metabolic process GO:0009259 231 0.046
regulation of phosphorylation GO:0042325 248 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.045
regulation of cellular amine metabolic process GO:0033238 8 0.045
response to other organism GO:0051707 220 0.043
Human
nucleoside phosphate metabolic process GO:0006753 283 0.042
purine containing compound metabolic process GO:0072521 253 0.042
response to mechanical stimulus GO:0009612 134 0.042
regulation of catalytic activity GO:0050790 304 0.042
rna biosynthetic process GO:0032774 380 0.042
cellular amino acid metabolic process GO:0006520 107 0.041
regulation of intracellular signal transduction GO:1902531 218 0.039
response to wounding GO:0009611 254 0.039
positive regulation of response to stimulus GO:0048584 285 0.039
cell type specific apoptotic process GO:0097285 134 0.039
immune response activating signal transduction GO:0002757 15 0.038
rna metabolic process GO:0016070 406 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.037
regeneration GO:0031099 163 0.037
regulation of protein phosphorylation GO:0001932 183 0.036
response to reactive oxygen species GO:0000302 120 0.036
intracellular transport GO:0046907 185 0.036
regulation of programmed cell death GO:0043067 341 0.036
positive regulation of rna biosynthetic process GO:1902680 197 0.036
negative regulation of response to stimulus GO:0048585 155 0.035
cellular component movement GO:0006928 248 0.035
regulation of cellular localization GO:0060341 263 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.035
anatomical structure formation involved in morphogenesis GO:0048646 83 0.035
secretion by cell GO:0032940 248 0.035
cell activation GO:0001775 97 0.035
amine metabolic process GO:0009308 38 0.034
cellular catabolic process GO:0044248 295 0.034
regulation of protein metabolic process GO:0051246 289 0.034
regulation of protein modification process GO:0031399 194 0.034
response to metal ion GO:0010038 253 0.034
protein complex assembly GO:0006461 263 0.033
positive regulation of molecular function GO:0044093 230 0.033
response to external biotic stimulus GO:0043207 221 0.033
Human
peptidyl tyrosine phosphorylation GO:0018108 72 0.033
response to bacterium GO:0009617 200 0.033
positive regulation of catalytic activity GO:0043085 184 0.033
catabolic process GO:0009056 351 0.032
apoptotic process GO:0006915 381 0.032
cellular response to stress GO:0033554 269 0.032
single organism biosynthetic process GO:0044711 342 0.031
oxoacid metabolic process GO:0043436 290 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.031
negative regulation of cell communication GO:0010648 158 0.031
endocytosis GO:0006897 84 0.031
nucleoside catabolic process GO:0009164 126 0.031
protein complex biogenesis GO:0070271 263 0.030
regulation of transcription dna templated GO:0006355 374 0.030
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
positive regulation of cell development GO:0010720 176 0.029
homeostatic process GO:0042592 331 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
sex differentiation GO:0007548 113 0.029
regulation of response to stress GO:0080134 126 0.029
organ regeneration GO:0031100 101 0.029
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
macromolecular complex assembly GO:0065003 273 0.028
cellular nitrogen compound catabolic process GO:0044270 163 0.028
multi organism reproductive process GO:0044703 262 0.028
positive regulation of phosphorylation GO:0042327 177 0.027
positive regulation of neuron apoptotic process GO:0043525 33 0.027
response to acid chemical GO:0001101 222 0.027
nucleoside metabolic process GO:0009116 179 0.027
mapk cascade GO:0000165 140 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
purine nucleoside triphosphate catabolic process GO:0009146 122 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
purine nucleotide metabolic process GO:0006163 229 0.025
cellular response to abiotic stimulus GO:0071214 85 0.025
purine nucleoside triphosphate metabolic process GO:0009144 141 0.025
organonitrogen compound biosynthetic process GO:1901566 167 0.025
carboxylic acid metabolic process GO:0019752 289 0.025
protein transport GO:0015031 132 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
regulation of cell differentiation GO:0045595 320 0.025
cytokine production GO:0001816 61 0.025
regulation of secretion GO:0051046 224 0.025
cellular component assembly GO:0022607 360 0.025
cellular amine metabolic process GO:0044106 38 0.024
cellular response to lipid GO:0071396 201 0.024
response to estradiol GO:0032355 164 0.024
negative regulation of signaling GO:0023057 157 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
response to estrogen GO:0043627 232 0.024
regulation of cell migration GO:0030334 128 0.023
response to cytokine GO:0034097 215 0.023
regulation of mapk cascade GO:0043408 116 0.023
cytoplasmic transport GO:0016482 115 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
nucleic acid templated transcription GO:0097659 379 0.023
positive regulation of apoptotic process GO:0043065 154 0.023
positive regulation of signaling GO:0023056 270 0.023
positive regulation of neuron death GO:1901216 43 0.023
locomotion GO:0040011 237 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
organic acid metabolic process GO:0006082 292 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
immune response GO:0006955 104 0.022
positive regulation of intracellular protein transport GO:0090316 20 0.022
immune response regulating signaling pathway GO:0002764 19 0.022
neuron differentiation GO:0030182 368 0.022
proteolysis GO:0006508 175 0.022
cellular response to peptide hormone stimulus GO:0071375 120 0.021
cell cycle checkpoint GO:0000075 2 0.021
brain development GO:0007420 247 0.021
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.021
protein autophosphorylation GO:0046777 66 0.021
ion transmembrane transport GO:0034220 365 0.021
response to biotic stimulus GO:0009607 226 0.021
Human
positive regulation of locomotion GO:0040017 102 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
negative regulation of metabolic process GO:0009892 331 0.021
negative regulation of phosphate metabolic process GO:0045936 80 0.020
multicellular organism reproduction GO:0032504 233 0.020
cellular response to reactive oxygen species GO:0034614 55 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
regulation of smooth muscle cell proliferation GO:0048660 75 0.020
gland development GO:0048732 155 0.020
establishment of protein localization GO:0045184 141 0.020
response to radiation GO:0009314 137 0.020
ribonucleoside catabolic process GO:0042454 126 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
regulation of apoptotic process GO:0042981 335 0.020
guanosine containing compound metabolic process GO:1901068 74 0.020
protein oligomerization GO:0051259 191 0.019
transmembrane transport GO:0055085 412 0.019
localization of cell GO:0051674 202 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
regulation of secretion by cell GO:1903530 208 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
negative regulation of molecular function GO:0044092 133 0.019
regulation of neurogenesis GO:0050767 247 0.019
muscle cell proliferation GO:0033002 84 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
single organism catabolic process GO:0044712 283 0.018
positive regulation of cell communication GO:0010647 271 0.018
central nervous system development GO:0007417 311 0.018
peptidyl tyrosine modification GO:0018212 72 0.018
sequestering of calcium ion GO:0051208 8 0.018
cell cycle process GO:0022402 57 0.018
Human
positive regulation of protein modification process GO:0031401 142 0.018
sensory perception GO:0007600 101 0.018
cellular response to external stimulus GO:0071496 118 0.018
negative regulation of signal transduction GO:0009968 83 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
organelle organization GO:0006996 266 0.017
regulation of cell development GO:0060284 263 0.017
single organism reproductive process GO:0044702 297 0.017
regulation of hydrolase activity GO:0051336 143 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
transcription dna templated GO:0006351 377 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
metal ion homeostasis GO:0055065 186 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
nucleotide catabolic process GO:0009166 139 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
chemical homeostasis GO:0048878 292 0.017
aromatic compound catabolic process GO:0019439 168 0.017
response to hypoxia GO:0001666 231 0.017
regulation of intracellular transport GO:0032386 65 0.016
regulation of protein localization GO:0032880 81 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
cell projection organization GO:0030030 302 0.016
negative regulation of transport GO:0051051 136 0.016
reproduction GO:0000003 245 0.016
regulation of establishment of protein localization GO:0070201 69 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
protein complex subunit organization GO:0071822 302 0.016
forebrain development GO:0030900 98 0.016
positive regulation of immune response GO:0050778 42 0.015
positive regulation of signal transduction GO:0009967 175 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
negative regulation of cell death GO:0060548 229 0.015
response to corticosteroid GO:0031960 235 0.015
positive regulation of secretion GO:0051047 140 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
cellular chemical homeostasis GO:0055082 247 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
calcium ion homeostasis GO:0055074 162 0.015
cell cell signaling GO:0007267 335 0.015
response to decreased oxygen levels GO:0036293 237 0.015
reproductive structure development GO:0048608 128 0.015
cell migration GO:0016477 197 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
cellular response to insulin stimulus GO:0032869 81 0.015
cell motility GO:0048870 202 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
positive regulation of mapk cascade GO:0043410 92 0.015
cellular response to oxidative stress GO:0034599 76 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
circulatory system process GO:0003013 183 0.014
maintenance of location GO:0051235 17 0.014
secretion GO:0046903 307 0.014
positive regulation of developmental process GO:0051094 283 0.014
cellular homeostasis GO:0019725 252 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
response to lipopolysaccharide GO:0032496 191 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
jnk cascade GO:0007254 28 0.014
metal ion transport GO:0030001 289 0.014
ras protein signal transduction GO:0007265 29 0.013
activation of cysteine type endopeptidase activity GO:0097202 4 0.013
organophosphate catabolic process GO:0046434 148 0.013
negative regulation of homeostatic process GO:0032845 47 0.013
regulation of interleukin 1 beta secretion GO:0050706 3 0.013
cell adhesion GO:0007155 110 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
multicellular organismal homeostasis GO:0048871 49 0.013
cation homeostasis GO:0055080 195 0.013
regulation of system process GO:0044057 208 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
female sex differentiation GO:0046660 59 0.013
aging GO:0007568 241 0.013
purine containing compound catabolic process GO:0072523 138 0.013
cardiovascular system development GO:0072358 134 0.013
axis specification GO:0009798 4 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.013
cellular macromolecule localization GO:0070727 122 0.013
developmental process involved in reproduction GO:0003006 159 0.013
macromolecule localization GO:0033036 252 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
neurological system process GO:0050877 219 0.013
cellular protein localization GO:0034613 122 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
cellular response to acid chemical GO:0071229 75 0.013
rhythmic process GO:0048511 156 0.012
neuron development GO:0048666 286 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
response to toxic substance GO:0009636 133 0.012
cellular component biogenesis GO:0044085 368 0.012
response to nutrient levels GO:0031667 370 0.012
rho protein signal transduction GO:0007266 11 0.012
response to ethanol GO:0045471 162 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of protein transport GO:0051222 41 0.012
spermatogenesis GO:0007283 99 0.012
regulation of embryonic development GO:0045995 2 0.012
response to oxygen levels GO:0070482 265 0.012
regulation of protein transport GO:0051223 68 0.012
single organism organelle organization GO:1902589 180 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
regulation of cellular component movement GO:0051270 150 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of body fluid levels GO:0050878 90 0.012
regulation of protein kinase activity GO:0045859 105 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
muscle cell differentiation GO:0042692 52 0.012
regulation of homeostatic process GO:0032844 101 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
myoblast fusion GO:0007520 2 0.011
regulation of cell projection organization GO:0031344 175 0.011
dna metabolic process GO:0006259 96 0.011
regulation of kinase activity GO:0043549 117 0.011
response to nutrient GO:0007584 248 0.011
positive regulation of transport GO:0051050 245 0.011
erythrocyte homeostasis GO:0034101 2 0.011
syncytium formation by plasma membrane fusion GO:0000768 3 0.011
reproductive system development GO:0061458 128 0.011
behavior GO:0007610 205 0.011
antigen receptor mediated signaling pathway GO:0050851 1 0.011
response to monosaccharide GO:0034284 159 0.011
intracellular protein transport GO:0006886 79 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
actin filament based movement GO:0030048 16 0.011
head development GO:0060322 247 0.011
defense response to gram positive bacterium GO:0050830 2 0.011
cation transport GO:0006812 382 0.011
regulation of neuron differentiation GO:0045664 208 0.011
palate development GO:0060021 2 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
tissue development GO:0009888 252 0.011
angiogenesis GO:0001525 53 0.011
female gonad development GO:0008585 53 0.011
macromolecular complex subunit organization GO:0043933 339 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
response to ionizing radiation GO:0010212 59 0.010
leukocyte activation GO:0045321 76 0.010
response to alkaloid GO:0043279 132 0.010
response to ketone GO:1901654 182 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
ion homeostasis GO:0050801 212 0.010
tube development GO:0035295 89 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
positive regulation of humoral immune response GO:0002922 2 0.010
hemopoiesis GO:0030097 34 0.010
blood vessel morphogenesis GO:0048514 58 0.010

Slfn8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013