Rattus norvegicus

120 known processes

Slit1

slit homolog 1 (Drosophila)

(Aliases: MEGF4)

Slit1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.346
brain development GO:0007420 247 0.335
regulation of hormone levels GO:0010817 187 0.260
cell part morphogenesis GO:0032990 123 0.247
cell projection morphogenesis GO:0048858 123 0.218
apoptotic process GO:0006915 381 0.206
protein phosphorylation GO:0006468 345 0.197
neuron projection morphogenesis GO:0048812 122 0.182
response to monosaccharide GO:0034284 159 0.162
head development GO:0060322 247 0.162
response to extracellular stimulus GO:0009991 380 0.160
Rat
cation transport GO:0006812 382 0.149
regulation of apoptotic process GO:0042981 335 0.140
neuron development GO:0048666 286 0.140
cellular response to oxygen containing compound GO:1901701 386 0.131
secretion GO:0046903 307 0.130
regulation of cell proliferation GO:0042127 359 0.123
behavior GO:0007610 205 0.123
developmental growth GO:0048589 100 0.122
neuron death GO:0070997 127 0.119
regulation of anatomical structure size GO:0090066 135 0.110
positive regulation of developmental process GO:0051094 283 0.104
Zebrafish
neuron projection development GO:0031175 273 0.102
cellular response to endogenous stimulus GO:0071495 377 0.101
protein localization GO:0008104 191 0.101
cellular response to growth factor stimulus GO:0071363 162 0.099
response to estrogen GO:0043627 232 0.098
regulation of molecular function GO:0065009 398 0.093
regulation of catalytic activity GO:0050790 304 0.093
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.092
cell morphogenesis GO:0000902 142 0.091
intracellular signal transduction GO:0035556 314 0.088
axon guidance GO:0007411 24 0.087
tissue development GO:0009888 252 0.085
Fly
vascular process in circulatory system GO:0003018 96 0.084
positive regulation of multicellular organismal process GO:0051240 387 0.084
Zebrafish
anatomical structure morphogenesis GO:0009653 298 0.077
positive regulation of cell communication GO:0010647 271 0.077
regulation of secretion by cell GO:1903530 208 0.075
inorganic cation transmembrane transport GO:0098662 202 0.074
dna metabolic process GO:0006259 96 0.072
positive regulation of catalytic activity GO:0043085 184 0.072
response to ketone GO:1901654 182 0.072
regulation of protein metabolic process GO:0051246 289 0.071
macromolecule localization GO:0033036 252 0.071
regulation of neuron death GO:1901214 115 0.070
cation transmembrane transport GO:0098655 263 0.070
sensory organ development GO:0007423 74 0.069
reproductive system development GO:0061458 128 0.069
Fly
epithelial cell differentiation GO:0030855 71 0.067
cell cell signaling GO:0007267 335 0.065
Zebrafish Fly
cell projection organization GO:0030030 302 0.065
positive regulation of molecular function GO:0044093 230 0.064
negative regulation of apoptotic process GO:0043066 181 0.063
neuron apoptotic process GO:0051402 88 0.063
regulation of transferase activity GO:0051338 123 0.059
response to ethanol GO:0045471 162 0.059
response to wounding GO:0009611 254 0.057
Rat
axonogenesis GO:0007409 71 0.056
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
chemical homeostasis GO:0048878 292 0.055
salivary gland development GO:0007431 3 0.054
Fly
positive regulation of kinase activity GO:0033674 77 0.054
cell morphogenesis involved in differentiation GO:0000904 119 0.054
positive regulation of long term synaptic potentiation GO:1900273 4 0.054
cellular response to stress GO:0033554 269 0.054
transmembrane transport GO:0055085 412 0.053
regulation of protein kinase activity GO:0045859 105 0.053
cellular homeostasis GO:0019725 252 0.052
aging GO:0007568 241 0.052
organic acid metabolic process GO:0006082 292 0.050
homeostatic process GO:0042592 331 0.050
regulation of phosphorus metabolic process GO:0051174 349 0.050
cellular response to hormone stimulus GO:0032870 247 0.050
positive regulation of transport GO:0051050 245 0.050
hormone secretion GO:0046879 115 0.049
positive regulation of programmed cell death GO:0043068 157 0.049
cell type specific apoptotic process GO:0097285 134 0.049
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.049
protein transport GO:0015031 132 0.048
hormone transport GO:0009914 121 0.047
multi organism reproductive process GO:0044703 262 0.047
multicellular organism reproduction GO:0032504 233 0.047
response to growth factor GO:0070848 189 0.047
multi multicellular organism process GO:0044706 138 0.046
organonitrogen compound biosynthetic process GO:1901566 167 0.046
regulation of system process GO:0044057 208 0.044
cellular response to alcohol GO:0097306 87 0.044
positive regulation of ion transport GO:0043270 94 0.044
negative regulation of programmed cell death GO:0043069 183 0.044
negative regulation of cell death GO:0060548 229 0.044
response to ammonium ion GO:0060359 71 0.044
cellular ketone metabolic process GO:0042180 51 0.044
metal ion transport GO:0030001 289 0.044
divalent metal ion transport GO:0070838 132 0.044
dendrite development GO:0016358 72 0.043
Fly
regulation of blood vessel size GO:0050880 89 0.043
secretion by cell GO:0032940 248 0.043
regulation of dna metabolic process GO:0051052 60 0.043
respiratory gaseous exchange GO:0007585 4 0.043
response to cocaine GO:0042220 39 0.043
positive regulation of cell proliferation GO:0008284 249 0.043
regulation of programmed cell death GO:0043067 341 0.042
central nervous system development GO:0007417 311 0.042
regulation of nervous system development GO:0051960 264 0.041
carboxylic acid metabolic process GO:0019752 289 0.041
positive regulation of phosphorylation GO:0042327 177 0.040
regulation of phosphorylation GO:0042325 248 0.040
regulation of ion transport GO:0043269 245 0.040
positive regulation of signaling GO:0023056 270 0.039
multicellular organismal reproductive process GO:0048609 233 0.039
taxis GO:0042330 67 0.039
positive regulation of cellular component organization GO:0051130 200 0.039
Zebrafish
reproductive structure development GO:0048608 128 0.039
Fly
catabolic process GO:0009056 351 0.038
positive regulation of apoptotic process GO:0043065 154 0.038
organophosphate metabolic process GO:0019637 370 0.038
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.038
blood circulation GO:0008015 183 0.038
negative regulation of metabolic process GO:0009892 331 0.038
intracellular transport GO:0046907 185 0.038
regulation of cellular component organization GO:0051128 368 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.037
regulation of cell motility GO:2000145 131 0.037
Rat Fly
positive regulation of protein kinase activity GO:0045860 73 0.037
regulation of cell development GO:0060284 263 0.037
neuron differentiation GO:0030182 368 0.037
membrane organization GO:0061024 94 0.037
positive regulation of phosphorus metabolic process GO:0010562 262 0.036
rna biosynthetic process GO:0032774 380 0.036
response to vitamin GO:0033273 131 0.036
carbohydrate metabolic process GO:0005975 130 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.036
response to peptide hormone GO:0043434 278 0.035
regulation of protein serine threonine kinase activity GO:0071900 64 0.035
response to glucose GO:0009749 136 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
regulation of rna metabolic process GO:0051252 391 0.034
regulation of locomotion GO:0040012 148 0.034
positive regulation of cell development GO:0010720 176 0.034
Zebrafish
regulation of multicellular organismal development GO:2000026 376 0.034
organelle organization GO:0006996 266 0.034
reproductive process GO:0022414 372 0.034
Fly
carbohydrate derivative metabolic process GO:1901135 346 0.034
multicellular organismal signaling GO:0035637 44 0.034
eye development GO:0001654 50 0.034
establishment of protein localization GO:0045184 141 0.034
regulation of intracellular signal transduction GO:1902531 218 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.033
single organism biosynthetic process GO:0044711 342 0.033
circulatory system process GO:0003013 183 0.033
positive regulation of biosynthetic process GO:0009891 319 0.033
amine metabolic process GO:0009308 38 0.033
inorganic ion transmembrane transport GO:0098660 229 0.033
purine ribonucleotide metabolic process GO:0009150 227 0.033
signal release GO:0023061 145 0.032
motor neuron axon guidance GO:0008045 1 0.032
Human
organic hydroxy compound metabolic process GO:1901615 115 0.032
response to acid chemical GO:0001101 222 0.032
regulation of hormone secretion GO:0046883 106 0.032
response to peptide GO:1901652 292 0.032
regulation of protein transport GO:0051223 68 0.031
regulation of kinase activity GO:0043549 117 0.031
positive regulation of cell differentiation GO:0045597 217 0.031
Zebrafish
positive regulation of protein modification process GO:0031401 142 0.031
calcium ion transport GO:0006816 131 0.031
amide transport GO:0042886 105 0.031
negative regulation of protein metabolic process GO:0051248 114 0.030
cell motility GO:0048870 202 0.030
Mouse Rat Worm Fly
regulation of neurogenesis GO:0050767 247 0.030
positive regulation of hormone secretion GO:0046887 65 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
regulation of neuron apoptotic process GO:0043523 83 0.030
response to estradiol GO:0032355 164 0.029
growth GO:0040007 165 0.029
monovalent inorganic cation transport GO:0015672 172 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
regulation of membrane potential GO:0042391 110 0.029
positive regulation of cell death GO:0010942 184 0.029
peptide transport GO:0015833 97 0.028
positive regulation of cellular amine metabolic process GO:0033240 3 0.028
response to hexose GO:0009746 144 0.028
response to inorganic substance GO:0010035 377 0.028
multicellular organismal homeostasis GO:0048871 49 0.027
cellular response to nitrogen compound GO:1901699 210 0.027
positive regulation of dna metabolic process GO:0051054 39 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
cellular protein localization GO:0034613 122 0.027
positive regulation of humoral immune response GO:0002922 2 0.027
regulation of protein modification process GO:0031399 194 0.027
response to alkaloid GO:0043279 132 0.027
regulation of transcription dna templated GO:0006355 374 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
Fly
oxoacid metabolic process GO:0043436 290 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
small gtpase mediated signal transduction GO:0007264 36 0.026
response to insulin GO:0032868 133 0.026
organic substance catabolic process GO:1901575 316 0.026
regulation of axonogenesis GO:0050770 37 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
regulation of cell cycle GO:0051726 73 0.026
reproduction GO:0000003 245 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
response to corticosteroid GO:0031960 235 0.026
cell growth GO:0016049 104 0.025
response to oxygen levels GO:0070482 265 0.025
response to mineralocorticoid GO:0051385 49 0.025
male sex differentiation GO:0046661 64 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.025
regulation of peptide hormone secretion GO:0090276 80 0.025
regulation of map kinase activity GO:0043405 53 0.025
regulation of cell growth GO:0001558 85 0.025
negative regulation of neuron death GO:1901215 69 0.024
cellular catabolic process GO:0044248 295 0.024
positive regulation of blood circulation GO:1903524 65 0.024
regulation of catabolic process GO:0009894 113 0.024
transcription dna templated GO:0006351 377 0.024
multicellular organism growth GO:0035264 1 0.024
cellular component morphogenesis GO:0032989 155 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
negative regulation of cellular protein metabolic process GO:0032269 106 0.023
ion homeostasis GO:0050801 212 0.023
response to nutrient levels GO:0031667 370 0.023
Rat
action potential GO:0001508 54 0.023
striated muscle contraction GO:0006941 44 0.023
potassium ion transport GO:0006813 97 0.023
circadian rhythm GO:0007623 88 0.023
regulation of axon extension GO:0030516 24 0.023
response to biotic stimulus GO:0009607 226 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
ion transmembrane transport GO:0034220 365 0.022
regulation of growth GO:0040008 105 0.022
regulation of peptide transport GO:0090087 87 0.022
cellular response to peptide hormone stimulus GO:0071375 120 0.022
axon development GO:0061564 96 0.022
organic acid transport GO:0015849 116 0.022
cellular amine metabolic process GO:0044106 38 0.022
regulation of rna biosynthetic process GO:2001141 381 0.021
rna metabolic process GO:0016070 406 0.021
cellular macromolecule localization GO:0070727 122 0.021
regulation of calcium ion transport GO:0051924 77 0.021
respiratory system process GO:0003016 3 0.021
positive regulation of secretion by cell GO:1903532 128 0.021
negative regulation of phosphate metabolic process GO:0045936 80 0.021
regulation of developmental growth GO:0048638 45 0.021
protein localization to membrane GO:0072657 36 0.021
transmission of nerve impulse GO:0019226 42 0.021
positive regulation of nucleotide metabolic process GO:0045981 91 0.021
myelination GO:0042552 39 0.021
lymphoid progenitor cell differentiation GO:0002320 2 0.021
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
single organism behavior GO:0044708 130 0.021
single organism reproductive process GO:0044702 297 0.020
Fly
response to oxidative stress GO:0006979 186 0.020
regulation of secretion GO:0051046 224 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
nucleic acid templated transcription GO:0097659 379 0.020
amino acid transport GO:0006865 70 0.020
positive regulation of protein secretion GO:0050714 19 0.020
salivary gland morphogenesis GO:0007435 1 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.020
epithelium development GO:0060429 96 0.020
Fly
positive regulation of peptide hormone secretion GO:0090277 50 0.020
regulation of endocytosis GO:0030100 42 0.020
protein autophosphorylation GO:0046777 66 0.020
single organism intracellular transport GO:1902582 166 0.020
calcium ion transmembrane transport GO:0070588 70 0.020
regulation of body fluid levels GO:0050878 90 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
localization of cell GO:0051674 202 0.019
Mouse Rat Worm Fly
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.019
response to glucocorticoid GO:0051384 223 0.019
regulation of blood circulation GO:1903522 110 0.019
single organism catabolic process GO:0044712 283 0.019
response to hypoxia GO:0001666 231 0.019
negative regulation of catalytic activity GO:0043086 103 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
regulation of extent of cell growth GO:0061387 25 0.019
peptide secretion GO:0002790 86 0.019
axon ensheathment GO:0008366 40 0.019
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.019
regulation of camp metabolic process GO:0030814 43 0.019
regulation of peptide secretion GO:0002791 82 0.019
mapk cascade GO:0000165 140 0.019
cellular component movement GO:0006928 248 0.019
macromolecule catabolic process GO:0009057 58 0.019
positive regulation of nervous system development GO:0051962 178 0.019
Zebrafish
activation of protein kinase activity GO:0032147 47 0.019
negative regulation of transport GO:0051051 136 0.019
metanephric comma shaped body morphogenesis GO:0072278 2 0.019
negative regulation of secretion GO:0051048 82 0.019
divalent inorganic cation transport GO:0072511 134 0.018
positive regulation of renin secretion into blood stream GO:1900135 1 0.018
positive regulation of vasodilation GO:0045909 29 0.018
regulation of proteasomal protein catabolic process GO:0061136 4 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
vasodilation GO:0042311 44 0.018
locomotion GO:0040011 237 0.018
camera type eye development GO:0043010 48 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
regulation of tube size GO:0035150 89 0.018
glutamine family amino acid metabolic process GO:0009064 15 0.017
learning or memory GO:0007611 90 0.017
peptidyl tyrosine phosphorylation GO:0018108 72 0.017
cellular response to acid chemical GO:0071229 75 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
gonad development GO:0008406 104 0.017
Fly
nucleotide metabolic process GO:0009117 279 0.017
regulation of cell projection organization GO:0031344 175 0.017
peptide hormone secretion GO:0030072 84 0.017
ras protein signal transduction GO:0007265 29 0.017
negative regulation of cell communication GO:0010648 158 0.017
spindle organization GO:0007051 2 0.017
intracellular protein transport GO:0006886 79 0.017
cell cycle process GO:0022402 57 0.017
negative regulation of growth GO:0045926 37 0.017
response to nutrient GO:0007584 248 0.016
cellular component biogenesis GO:0044085 368 0.016
Zebrafish
dorsal ventral axon guidance GO:0033563 1 0.016
Mouse Worm
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
positive regulation of peptide secretion GO:0002793 52 0.016
response to corticosterone GO:0051412 40 0.016
protein catabolic process GO:0030163 30 0.016
negative regulation of protein phosphorylation GO:0001933 44 0.016
chemotaxis GO:0006935 66 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
Zebrafish
gliogenesis GO:0042063 93 0.016
Fly
protein secretion GO:0009306 34 0.016
cellular cation homeostasis GO:0030003 180 0.016
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.016
carboxylic acid transport GO:0046942 115 0.016
cyclic nucleotide metabolic process GO:0009187 80 0.015
nitrogen compound transport GO:0071705 229 0.015
oxidation reduction process GO:0055114 304 0.015
single organism membrane organization GO:0044802 74 0.015
development of primary sexual characteristics GO:0045137 107 0.015
Fly
g protein coupled acetylcholine receptor signaling pathway GO:0007213 5 0.015
regulation of hydrolase activity GO:0051336 143 0.015
regulation of cell size GO:0008361 37 0.015
sex differentiation GO:0007548 113 0.015
Fly
negative regulation of synaptic transmission glutamatergic GO:0051967 8 0.015
positive regulation of lipid kinase activity GO:0090218 2 0.015
regulation of neuron differentiation GO:0045664 208 0.015
cognition GO:0050890 92 0.015
regulation of vasodilation GO:0042312 36 0.015
ensheathment of neurons GO:0007272 40 0.014
astrocyte development GO:0014002 4 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
glial cell differentiation GO:0010001 65 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
Zebrafish
mitotic cell cycle process GO:1903047 35 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
anion transport GO:0006820 178 0.014
regulation of organelle organization GO:0033043 80 0.014
peptidyl amino acid modification GO:0018193 126 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
cellular response to magnesium ion GO:0071286 4 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
metanephric s shaped body morphogenesis GO:0072284 2 0.014
axon choice point recognition GO:0016198 2 0.014
Fly
arginine metabolic process GO:0006525 6 0.014
response to dexamethasone GO:0071548 49 0.014
heart contraction GO:0060047 57 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
response to reactive oxygen species GO:0000302 120 0.014
negative regulation of protein kinase activity GO:0006469 23 0.014
regulation of cellular catabolic process GO:0031329 101 0.013
alpha amino acid metabolic process GO:1901605 71 0.013
positive regulation of protein transport GO:0051222 41 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.013
cellular response to oxidative stress GO:0034599 76 0.013
chemosensory behavior GO:0007635 2 0.013
dna replication GO:0006260 37 0.013
cellular response to steroid hormone stimulus GO:0071383 93 0.013
nuclear transport GO:0051169 49 0.013
positive regulation of camp metabolic process GO:0030816 31 0.013
positive regulation of transferase activity GO:0051347 81 0.013
cellular response to external stimulus GO:0071496 118 0.013
single organism cellular localization GO:1902580 102 0.013
regulation of nucleic acid templated transcription GO:1903506 380 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
cerebellar purkinje cell layer development GO:0021680 2 0.013
sensory perception GO:0007600 101 0.013
cellular component assembly GO:0022607 360 0.013
Zebrafish
ribonucleotide biosynthetic process GO:0009260 85 0.013
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.013
adult locomotory behavior GO:0008344 4 0.013
negative regulation of phosphorylation GO:0042326 57 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
regulation of response to external stimulus GO:0032101 106 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
gamete generation GO:0007276 124 0.013
positive regulation of organelle organization GO:0010638 48 0.012
neuronal action potential GO:0019228 35 0.012
chromosome separation GO:0051304 1 0.012
activation of protein kinase b activity GO:0032148 3 0.012
prepulse inhibition GO:0060134 1 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
developmental process involved in reproduction GO:0003006 159 0.012
Fly
single organism organelle organization GO:1902589 180 0.012
negative regulation of transferase activity GO:0051348 29 0.012
carboxylic acid catabolic process GO:0046395 49 0.012
renin secretion into blood stream GO:0002001 1 0.012
cell cycle checkpoint GO:0000075 2 0.012
negative regulation of protein modification process GO:0031400 52 0.012
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.012
response to external biotic stimulus GO:0043207 221 0.012
forebrain development GO:0030900 98 0.012
Mouse
defense response GO:0006952 194 0.012
Rat
cellular ion homeostasis GO:0006873 184 0.012
dephosphorylation GO:0016311 98 0.012
insulin secretion GO:0030073 69 0.012
positive regulation of catabolic process GO:0009896 78 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
regulation of mapk cascade GO:0043408 116 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.012
regulation of vascular smooth muscle contraction GO:0003056 3 0.012
negative regulation of cell proliferation GO:0008285 119 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
organic acid catabolic process GO:0016054 49 0.011
purine containing compound metabolic process GO:0072521 253 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
organ regeneration GO:0031100 101 0.011
muscle contraction GO:0006936 88 0.011
regulation of signal transduction GO:0009966 318 0.011
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
hormone metabolic process GO:0042445 69 0.011
cell cycle GO:0007049 101 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
secretion by tissue GO:0032941 37 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
positive regulation of membrane potential GO:0045838 16 0.011
regulation of vasoconstriction GO:0019229 44 0.011
positive regulation of growth GO:0045927 55 0.011
Zebrafish
negative regulation of kinase activity GO:0033673 27 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
molting cycle GO:0042303 3 0.011
regulation of neuron projection development GO:0010975 161 0.011
sexual reproduction GO:0019953 148 0.011
cellular glucan metabolic process GO:0006073 23 0.011
protein dephosphorylation GO:0006470 38 0.011
interleukin 6 production GO:0032635 12 0.011
negative regulation of molecular function GO:0044092 133 0.011
positive regulation of signal transduction GO:0009967 175 0.011
positive regulation of lipid metabolic process GO:0045834 33 0.011
monoamine transport GO:0015844 43 0.011
response to carbohydrate GO:0009743 183 0.011
polysaccharide metabolic process GO:0005976 25 0.011
acute inflammatory response GO:0002526 58 0.011
cation homeostasis GO:0055080 195 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.010
nucleocytoplasmic transport GO:0006913 48 0.010
negative regulation of signal transduction GO:0009968 83 0.010
regulation of protein localization GO:0032880 81 0.010
response to antibiotic GO:0046677 39 0.010
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.010
negative regulation of gene expression GO:0010629 199 0.010
wound healing GO:0042060 122 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
synaptic transmission glutamatergic GO:0035249 33 0.010
protein maturation GO:0051604 68 0.010
regulation of cell cycle g2 m phase transition GO:1902749 4 0.010
muscle cell proliferation GO:0033002 84 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
cell migration GO:0016477 197 0.010
Mouse Rat Worm Fly
proteolysis GO:0006508 175 0.010
regulation of transporter activity GO:0032409 50 0.010
cellular response to reactive oxygen species GO:0034614 55 0.010

Slit1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.059
central nervous system disease DOID:331 0 0.022
sensory system disease DOID:0050155 0 0.019