Rattus norvegicus

158 known processes

Smad1

SMAD family member 1

(Aliases: Madh1)

Smad1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.720
transcription from rna polymerase ii promoter GO:0006366 252 0.613
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.501
apoptotic process GO:0006915 381 0.499
regulation of cellular protein metabolic process GO:0032268 267 0.479
Rat
nucleic acid templated transcription GO:0097659 379 0.475
response to wounding GO:0009611 254 0.472
negative regulation of apoptotic process GO:0043066 181 0.465
negative regulation of cell death GO:0060548 229 0.446
regulation of rna metabolic process GO:0051252 391 0.431
positive regulation of multicellular organismal process GO:0051240 387 0.429
cell type specific apoptotic process GO:0097285 134 0.425
regulation of rna biosynthetic process GO:2001141 381 0.389
regulation of nucleic acid templated transcription GO:1903506 380 0.376
anatomical structure morphogenesis GO:0009653 298 0.358
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.357
Rat
positive regulation of rna metabolic process GO:0051254 203 0.350
Rat
rna biosynthetic process GO:0032774 380 0.349
regulation of cell development GO:0060284 263 0.348
regulation of cellular component movement GO:0051270 150 0.341
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.331
Rat
intracellular signal transduction GO:0035556 314 0.325
immune system process GO:0002376 204 0.315
regulation of phosphorus metabolic process GO:0051174 349 0.306
Rat
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.306
Rat
response to hydrogen peroxide GO:0042542 89 0.299
programmed cell death GO:0012501 392 0.299
enzyme linked receptor protein signaling pathway GO:0007167 116 0.292
regulation of programmed cell death GO:0043067 341 0.290
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.279
Rat
positive regulation of biosynthetic process GO:0009891 319 0.278
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.270
Rat
positive regulation of gene expression GO:0010628 244 0.253
Human Rat
response to estrogen GO:0043627 232 0.251
Rat
regulation of multicellular organismal development GO:2000026 376 0.248
regulation of apoptotic process GO:0042981 335 0.248
response to cytokine GO:0034097 215 0.244
positive regulation of rna biosynthetic process GO:1902680 197 0.242
Rat
central nervous system development GO:0007417 311 0.242
positive regulation of response to stimulus GO:0048584 285 0.240
Rat
regulation of transcription dna templated GO:0006355 374 0.239
response to decreased oxygen levels GO:0036293 237 0.231
Rat
response to mechanical stimulus GO:0009612 134 0.229
rna metabolic process GO:0016070 406 0.225
neuron development GO:0048666 286 0.224
positive regulation of developmental process GO:0051094 283 0.216
negative regulation of muscle cell apoptotic process GO:0010656 21 0.211
positive regulation of signal transduction GO:0009967 175 0.211
Rat
response to oxidative stress GO:0006979 186 0.210
regulation of cell differentiation GO:0045595 320 0.209
apoptotic signaling pathway GO:0097190 27 0.208
Rat
response to inorganic substance GO:0010035 377 0.204
organelle organization GO:0006996 266 0.202
Rat
regulation of neuron death GO:1901214 115 0.202
regulation of phosphorylation GO:0042325 248 0.199
negative regulation of multicellular organismal process GO:0051241 203 0.194
neuron projection development GO:0031175 273 0.193
positive regulation of cellular protein metabolic process GO:0032270 167 0.192
Rat
behavior GO:0007610 205 0.191
Rat
development of primary sexual characteristics GO:0045137 107 0.189
head development GO:0060322 247 0.188
cellular response to hormone stimulus GO:0032870 247 0.188
cellular response to endogenous stimulus GO:0071495 377 0.187
Rat
regulation of phosphate metabolic process GO:0019220 349 0.186
Rat
regulation of cell proliferation GO:0042127 359 0.185
Rat
neuron differentiation GO:0030182 368 0.185
response to reactive oxygen species GO:0000302 120 0.183
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.182
Rat
muscle cell proliferation GO:0033002 84 0.181
negative regulation of programmed cell death GO:0043069 183 0.179
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.178
Rat
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.177
regulation of neurogenesis GO:0050767 247 0.176
neuron death GO:0070997 127 0.175
protein phosphorylation GO:0006468 345 0.175
negative regulation of transcription dna templated GO:0045892 116 0.173
Rat
gland development GO:0048732 155 0.171
response to oxygen levels GO:0070482 265 0.171
Rat
cellular response to lipid GO:0071396 201 0.167
regulation of cell migration GO:0030334 128 0.166
Rat
peptidyl amino acid modification GO:0018193 126 0.163
response to molecule of bacterial origin GO:0002237 194 0.163
blood vessel morphogenesis GO:0048514 58 0.159
signal transduction by phosphorylation GO:0023014 144 0.158
regulation of cellular component organization GO:0051128 368 0.156
organic acid metabolic process GO:0006082 292 0.156
cellular response to stress GO:0033554 269 0.155
cell morphogenesis GO:0000902 142 0.155
regulation of mesenchymal cell proliferation GO:0010464 4 0.153
cytokine mediated signaling pathway GO:0019221 43 0.153
regulation of molecular function GO:0065009 398 0.152
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.151
cellular response to cytokine stimulus GO:0071345 127 0.149
positive regulation of cell communication GO:0010647 271 0.149
Rat
positive regulation of cell death GO:0010942 184 0.147
Rat
cell adhesion GO:0007155 110 0.146
Rat
positive regulation of cell development GO:0010720 176 0.142
regulation of catalytic activity GO:0050790 304 0.142
Rat
negative regulation of developmental process GO:0051093 125 0.142
cellular component movement GO:0006928 248 0.141
Rat
regulation of protein metabolic process GO:0051246 289 0.141
Rat
regulation of immune system process GO:0002682 123 0.140
circulatory system development GO:0072359 134 0.140
positive regulation of phosphorus metabolic process GO:0010562 262 0.139
Rat
cellular response to organonitrogen compound GO:0071417 197 0.138
brain development GO:0007420 247 0.136
cellular ketone metabolic process GO:0042180 51 0.134
anatomical structure formation involved in morphogenesis GO:0048646 83 0.133
amine metabolic process GO:0009308 38 0.133
regulation of intracellular signal transduction GO:1902531 218 0.133
mapk cascade GO:0000165 140 0.132
regulation of neuron apoptotic process GO:0043523 83 0.132
response to other organism GO:0051707 220 0.132
regulation of protein modification process GO:0031399 194 0.132
proteolysis GO:0006508 175 0.129
Rat
response to hypoxia GO:0001666 231 0.129
Rat
reproductive process GO:0022414 372 0.128
Rat
positive regulation of protein metabolic process GO:0051247 178 0.127
Rat
biological adhesion GO:0022610 110 0.127
Rat
cellular response to oxygen containing compound GO:1901701 386 0.127
wound healing GO:0042060 122 0.126
positive regulation of signaling GO:0023056 270 0.125
Rat
positive regulation of cellular component movement GO:0051272 102 0.121
Rat
localization of cell GO:0051674 202 0.121
Rat
cellular chemical homeostasis GO:0055082 247 0.118
regulation of neuron projection development GO:0010975 161 0.118
response to metal ion GO:0010038 253 0.118
positive regulation of apoptotic process GO:0043065 154 0.116
Rat
cell migration GO:0016477 197 0.116
Rat
carboxylic acid metabolic process GO:0019752 289 0.114
regulation of anatomical structure morphogenesis GO:0022603 141 0.114
regulation of system process GO:0044057 208 0.114
oxoacid metabolic process GO:0043436 290 0.111
response to estradiol GO:0032355 164 0.110
positive regulation of cellular biosynthetic process GO:0031328 295 0.109
Rat
regulation of signal transduction GO:0009966 318 0.108
Rat
tissue development GO:0009888 252 0.108
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.107
Rat
neurological system process GO:0050877 219 0.107
positive regulation of programmed cell death GO:0043068 157 0.107
Rat
negative regulation of metabolic process GO:0009892 331 0.106
Rat
single organism reproductive process GO:0044702 297 0.106
Rat
response to acid chemical GO:0001101 222 0.106
regulation of cell motility GO:2000145 131 0.106
Rat
circulatory system process GO:0003013 183 0.105
cell projection organization GO:0030030 302 0.104
protein maturation GO:0051604 68 0.103
Rat
cellular response to organic cyclic compound GO:0071407 202 0.101
angiogenesis GO:0001525 53 0.100
rhythmic process GO:0048511 156 0.099
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.099
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.097
regulation of protein phosphorylation GO:0001932 183 0.097
mesenchymal cell proliferation GO:0010463 4 0.097
intracellular transport GO:0046907 185 0.094
response to growth factor GO:0070848 189 0.093
Rat
nucleotide metabolic process GO:0009117 279 0.093
growth GO:0040007 165 0.093
regulation of cytokine production GO:0001817 56 0.092
Rat
positive regulation of protein modification process GO:0031401 142 0.092
response to lipopolysaccharide GO:0032496 191 0.089
positive regulation of catalytic activity GO:0043085 184 0.088
Rat
regulation of apoptotic signaling pathway GO:2001233 13 0.087
Rat
regulation of locomotion GO:0040012 148 0.087
Rat
dephosphorylation GO:0016311 98 0.087
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.087
positive regulation of immune system process GO:0002684 90 0.086
regeneration GO:0031099 163 0.084
positive regulation of transcription dna templated GO:0045893 197 0.084
Rat
axon development GO:0061564 96 0.083
extrinsic apoptotic signaling pathway GO:0097191 10 0.083
learning or memory GO:0007611 90 0.082
regulation of protein kinase activity GO:0045859 105 0.082
positive regulation of molecular function GO:0044093 230 0.081
Rat
heart morphogenesis GO:0003007 3 0.081
gastrulation GO:0007369 2 0.079
macromolecular complex subunit organization GO:0043933 339 0.079
Human Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.079
Rat
myeloid leukocyte differentiation GO:0002573 20 0.079
secretion GO:0046903 307 0.078
negative regulation of gene expression GO:0010629 199 0.077
Rat
protein autophosphorylation GO:0046777 66 0.077
negative regulation of rna biosynthetic process GO:1902679 118 0.077
Rat
peptidyl tyrosine phosphorylation GO:0018108 72 0.076
cellular response to nitrogen compound GO:1901699 210 0.076
cellular response to peptide hormone stimulus GO:0071375 120 0.076
response to external biotic stimulus GO:0043207 221 0.076
inflammatory response GO:0006954 150 0.075
hematopoietic or lymphoid organ development GO:0048534 36 0.075
neuron apoptotic process GO:0051402 88 0.075
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.075
hepaticobiliary system development GO:0061008 90 0.074
peptidyl tyrosine modification GO:0018212 72 0.074
response to ethanol GO:0045471 162 0.073
cellular protein localization GO:0034613 122 0.073
positive regulation of neurogenesis GO:0050769 165 0.073
response to peptide GO:1901652 292 0.072
response to radiation GO:0009314 137 0.071
chemical homeostasis GO:0048878 292 0.071
regulation of cell morphogenesis GO:0022604 77 0.068
multicellular organism reproduction GO:0032504 233 0.068
organophosphate metabolic process GO:0019637 370 0.067
cellular response to tumor necrosis factor GO:0071356 46 0.067
epithelial cell differentiation GO:0030855 71 0.067
negative regulation of biosynthetic process GO:0009890 168 0.066
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.065
reproductive system development GO:0061458 128 0.065
cellular component morphogenesis GO:0032989 155 0.065
cellular amino acid metabolic process GO:0006520 107 0.065
regulation of response to stress GO:0080134 126 0.065
developmental process involved in reproduction GO:0003006 159 0.065
Rat
positive regulation of phosphorylation GO:0042327 177 0.065
positive regulation of cell migration GO:0030335 96 0.063
Rat
single organism organelle organization GO:1902589 180 0.063
Rat
sex differentiation GO:0007548 113 0.063
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.062
negative regulation of signal transduction GO:0009968 83 0.062
protein complex assembly GO:0006461 263 0.062
Human Rat
purine ribonucleotide metabolic process GO:0009150 227 0.062
protein complex biogenesis GO:0070271 263 0.062
Human Rat
vasculature development GO:0001944 70 0.061
regulation of stem cell proliferation GO:0072091 14 0.061
divalent metal ion transport GO:0070838 132 0.061
negative regulation of protein metabolic process GO:0051248 114 0.061
locomotion GO:0040011 237 0.060
Rat
cellular response to peptide GO:1901653 133 0.060
organ morphogenesis GO:0009887 75 0.060
regulation of cellular amine metabolic process GO:0033238 8 0.060
response to insulin GO:0032868 133 0.060
hemopoiesis GO:0030097 34 0.059
response to ketone GO:1901654 182 0.059
response to peptide hormone GO:0043434 278 0.059
negative regulation of macromolecule metabolic process GO:0010605 260 0.059
Rat
negative regulation of rna metabolic process GO:0051253 123 0.059
Rat
leukocyte activation GO:0045321 76 0.059
regulation of metanephros development GO:0072215 4 0.058
blood circulation GO:0008015 183 0.058
response to alkaloid GO:0043279 132 0.058
regulation of smooth muscle cell proliferation GO:0048660 75 0.058
liver development GO:0001889 90 0.058
cellular metal ion homeostasis GO:0006875 172 0.058
cellular homeostasis GO:0019725 252 0.058
defense response GO:0006952 194 0.057
regulation of blood circulation GO:1903522 110 0.057
regulation of growth GO:0040008 105 0.057
positive regulation of cellular component biogenesis GO:0044089 55 0.057
Rat
regulation of muscle cell apoptotic process GO:0010660 26 0.057
cellular amine metabolic process GO:0044106 38 0.057
cellular response to reactive oxygen species GO:0034614 55 0.057
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.056
negative regulation of cell proliferation GO:0008285 119 0.056
Rat
positive regulation of interleukin 1 beta production GO:0032731 6 0.056
Rat
homeostatic process GO:0042592 331 0.056
cellular response to ketone GO:1901655 51 0.056
cellular component assembly GO:0022607 360 0.055
Human Rat
cardiovascular system development GO:0072358 134 0.055
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.055
forebrain development GO:0030900 98 0.055
negative regulation of nucleic acid templated transcription GO:1903507 117 0.055
Rat
smooth muscle cell proliferation GO:0048659 77 0.055
embryonic pattern specification GO:0009880 1 0.055
multicellular organismal reproductive process GO:0048609 233 0.055
cell cycle GO:0007049 101 0.055
regulation of transforming growth factor beta3 production GO:0032910 2 0.055
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.055
epithelium development GO:0060429 96 0.055
positive regulation of cellular component organization GO:0051130 200 0.054
regulation of organelle organization GO:0033043 80 0.054
Rat
positive regulation of cell motility GO:2000147 97 0.054
Rat
response to interleukin 1 GO:0070555 55 0.053
digestive system development GO:0055123 41 0.053
establishment of protein localization GO:0045184 141 0.053
regulation of cellular amino acid metabolic process GO:0006521 2 0.053
positive regulation of cell differentiation GO:0045597 217 0.053
spindle organization GO:0007051 2 0.052
metal ion transport GO:0030001 289 0.052
immune response GO:0006955 104 0.052
positive regulation of protein transport GO:0051222 41 0.052
regulation of nervous system development GO:0051960 264 0.051
erythrocyte differentiation GO:0030218 1 0.051
development of primary female sexual characteristics GO:0046545 56 0.051
negative regulation of signaling GO:0023057 157 0.051
regulation of cell projection organization GO:0031344 175 0.051
response to biotic stimulus GO:0009607 226 0.050
nucleobase containing small molecule metabolic process GO:0055086 316 0.050
reproduction GO:0000003 245 0.050
negative regulation of cell differentiation GO:0045596 99 0.050
cellular component biogenesis GO:0044085 368 0.049
Human Rat
protein dephosphorylation GO:0006470 38 0.049
gonad development GO:0008406 104 0.049
regulation of mapk cascade GO:0043408 116 0.049
regulation of peptidase activity GO:0052547 55 0.049
Rat
protein complex subunit organization GO:0071822 302 0.049
Human Rat
carbohydrate derivative metabolic process GO:1901135 346 0.049
regulation of ion transport GO:0043269 245 0.048
cellular response to oxidative stress GO:0034599 76 0.048
regulation of map kinase activity GO:0043405 53 0.048
calcium ion transport GO:0006816 131 0.047
tube development GO:0035295 89 0.047
response to extracellular stimulus GO:0009991 380 0.047
positive regulation of cell proliferation GO:0008284 249 0.046
reproductive structure development GO:0048608 128 0.046
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.046
blood vessel development GO:0001568 69 0.046
cytoskeleton organization GO:0007010 111 0.046
Rat
regulation of immune response GO:0050776 55 0.046
aging GO:0007568 241 0.046
formation of primary germ layer GO:0001704 1 0.045
response to bacterium GO:0009617 200 0.045
metal ion homeostasis GO:0055065 186 0.045
reactive oxygen species metabolic process GO:0072593 37 0.045
positive regulation of protein phosphorylation GO:0001934 135 0.045
cation homeostasis GO:0055080 195 0.044
ovulation cycle process GO:0022602 50 0.044
organic substance catabolic process GO:1901575 316 0.044
positive regulation of nervous system development GO:0051962 178 0.044
response to hexose GO:0009746 144 0.044
bmp signaling pathway GO:0030509 4 0.044
ion homeostasis GO:0050801 212 0.044
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.044
Rat
negative regulation of transport GO:0051051 136 0.044
regulation of neuron differentiation GO:0045664 208 0.044
regulation of hydrolase activity GO:0051336 143 0.043
Rat
positive regulation of hydrolase activity GO:0051345 86 0.043
Rat
response to toxic substance GO:0009636 133 0.043
protein localization GO:0008104 191 0.043
cellular ion homeostasis GO:0006873 184 0.043
regulation of calcium ion transport GO:0051924 77 0.042
negative regulation of neuron apoptotic process GO:0043524 45 0.042
negative regulation of cellular component organization GO:0051129 83 0.042
cell motility GO:0048870 202 0.042
Rat
single organism intracellular transport GO:1902582 166 0.042
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.041
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.041
Rat
reactive oxygen species biosynthetic process GO:1903409 8 0.041
negative regulation of cell communication GO:0010648 158 0.040
transmembrane transport GO:0055085 412 0.040
response to transition metal nanoparticle GO:1990267 122 0.040
response to ionizing radiation GO:0010212 59 0.040
tissue regeneration GO:0042246 36 0.040
cognition GO:0050890 92 0.039
response to corticosteroid GO:0031960 235 0.039
cell activation GO:0001775 97 0.039
regulation of fat cell differentiation GO:0045598 3 0.039
response to axon injury GO:0048678 59 0.039
response to amino acid GO:0043200 75 0.038
divalent inorganic cation transport GO:0072511 134 0.038
regulation of response to external stimulus GO:0032101 106 0.038
Rat
cellular response to corticosteroid stimulus GO:0071384 69 0.038
positive regulation of immunoglobulin production GO:0002639 4 0.038
myeloid cell differentiation GO:0030099 22 0.038
sexual reproduction GO:0019953 148 0.038
negative regulation of neuron death GO:1901215 69 0.038
response to carbohydrate GO:0009743 183 0.037
regulation of reactive oxygen species metabolic process GO:2000377 26 0.037
positive regulation of mapk cascade GO:0043410 92 0.037
positive regulation of tumor necrosis factor production GO:0032760 8 0.037
developmental growth GO:0048589 100 0.037
calcium ion homeostasis GO:0055074 162 0.037
regulation of homeostatic process GO:0032844 101 0.037
actin filament bundle organization GO:0061572 19 0.036
Rat
axonogenesis GO:0007409 71 0.036
regulation of lipid metabolic process GO:0019216 68 0.036
activation of cysteine type endopeptidase activity GO:0097202 4 0.036
Rat
negative regulation of metanephros development GO:0072217 2 0.036
purine nucleoside triphosphate metabolic process GO:0009144 141 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.036
Rat
immune system development GO:0002520 41 0.035
protein transport GO:0015031 132 0.035
catabolic process GO:0009056 351 0.035
regulation of cell activation GO:0050865 50 0.035
regulation of metal ion transport GO:0010959 118 0.035
regulation of cellular localization GO:0060341 263 0.035
jak stat cascade GO:0007259 26 0.035
nucleoside triphosphate metabolic process GO:0009141 144 0.034
regulation of dna metabolic process GO:0051052 60 0.034
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.034
regulation of defense response GO:0031347 68 0.033
dna metabolic process GO:0006259 96 0.033
response to dexamethasone GO:0071548 49 0.033
cellular response to insulin stimulus GO:0032869 81 0.033
purine nucleotide biosynthetic process GO:0006164 83 0.032
mechanoreceptor differentiation GO:0042490 2 0.032
transforming growth factor beta3 production GO:0032907 2 0.032
Rat
single organism behavior GO:0044708 130 0.032
response to camp GO:0051591 91 0.032
response to purine containing compound GO:0014074 126 0.032
response to tumor necrosis factor GO:0034612 56 0.032
cellular response to growth factor stimulus GO:0071363 162 0.032
Rat
positive regulation of biomineral tissue development GO:0070169 4 0.032
Rat
cell part morphogenesis GO:0032990 123 0.032
cellular response to interleukin 1 GO:0071347 37 0.032
digestive tract development GO:0048565 39 0.032
cellular catabolic process GO:0044248 295 0.032
positive regulation of focal adhesion assembly GO:0051894 2 0.032
Rat
multicellular organism growth GO:0035264 1 0.032
negative regulation of cellular biosynthetic process GO:0031327 161 0.031
Rat
multi organism reproductive process GO:0044703 262 0.031
regulation of cell cycle GO:0051726 73 0.031
macromolecular complex assembly GO:0065003 273 0.031
Human Rat
muscle structure development GO:0061061 87 0.031
cellular response to lipopolysaccharide GO:0071222 55 0.031
negative regulation of kidney development GO:0090185 2 0.030
organophosphate biosynthetic process GO:0090407 143 0.030
positive regulation of behavior GO:0048520 38 0.030
Rat
cell cell signaling GO:0007267 335 0.030
positive regulation of kinase activity GO:0033674 77 0.030
cell junction organization GO:0034330 21 0.030
Rat
actin cytoskeleton organization GO:0030036 73 0.030
Rat
female sex differentiation GO:0046660 59 0.030
purine containing compound metabolic process GO:0072521 253 0.029
actin filament based process GO:0030029 86 0.029
Rat
muscle cell apoptotic process GO:0010657 30 0.029
positive regulation of locomotion GO:0040017 102 0.029
Rat
response to monosaccharide GO:0034284 159 0.029
purine ribonucleoside metabolic process GO:0046128 168 0.028
sequestering of calcium ion GO:0051208 8 0.028
erk1 and erk2 cascade GO:0070371 48 0.028
cell cycle process GO:0022402 57 0.028
purine nucleoside metabolic process GO:0042278 169 0.028
positive regulation of neuron differentiation GO:0045666 126 0.028
dendrite development GO:0016358 72 0.028
gamete generation GO:0007276 124 0.028
cellular response to alcohol GO:0097306 87 0.028
regulation of transferase activity GO:0051338 123 0.028
regulation of cytoskeleton organization GO:0051493 49 0.028
Rat
positive regulation of transport GO:0051050 245 0.028
cellular macromolecule localization GO:0070727 122 0.028
cellular calcium ion homeostasis GO:0006874 160 0.028
intracellular protein transport GO:0006886 79 0.028
regulation of protein localization GO:0032880 81 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.027
cytokine production GO:0001816 61 0.027
Rat
positive regulation of response to external stimulus GO:0032103 51 0.027
Rat
ameboidal type cell migration GO:0001667 26 0.027
motor neuron axon guidance GO:0008045 1 0.027
ribonucleoside triphosphate metabolic process GO:0009199 141 0.027
ribose phosphate metabolic process GO:0019693 235 0.026
oxidation reduction process GO:0055114 304 0.026
divalent inorganic cation homeostasis GO:0072507 165 0.026
negative regulation of molecular function GO:0044092 133 0.026
regulation of developmental growth GO:0048638 45 0.026
cellular response to acid chemical GO:0071229 75 0.026
lipid metabolic process GO:0006629 283 0.026
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.026
Rat
cell differentiation involved in kidney development GO:0061005 4 0.026
purine ribonucleotide biosynthetic process GO:0009152 81 0.026
positive regulation of neuron projection development GO:0010976 99 0.026
tissue morphogenesis GO:0048729 22 0.026
sensory perception GO:0007600 101 0.026
response to glucocorticoid GO:0051384 223 0.026
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003340 2 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
response to nutrient levels GO:0031667 370 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.025
Rat
regulation of cell substrate adhesion GO:0010810 18 0.025
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.025
limbic system development GO:0021761 38 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
Rat
protein heterooligomerization GO:0051291 89 0.024
striated muscle tissue development GO:0014706 58 0.024
neuron projection guidance GO:0097485 24 0.024
regulation of cytokine biosynthetic process GO:0042035 3 0.024
cation transport GO:0006812 382 0.024
dendrite morphogenesis GO:0048813 43 0.024
acute inflammatory response GO:0002526 58 0.024
regulation of epithelial cell differentiation GO:0030856 12 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
renal system development GO:0072001 67 0.024
cytoplasmic transport GO:0016482 115 0.024
negative regulation of neurogenesis GO:0050768 78 0.024
myoblast fusion GO:0007520 2 0.024
carbohydrate derivative biosynthetic process GO:1901137 124 0.024
vascular process in circulatory system GO:0003018 96 0.023
response to organophosphorus GO:0046683 102 0.023
response to glucose GO:0009749 136 0.023
positive regulation of cytokine production GO:0001819 42 0.023
Rat
leukocyte differentiation GO:0002521 30 0.023
protein import into nucleus GO:0006606 35 0.023
regulation of smooth muscle cell migration GO:0014910 36 0.023
regulation of hormone levels GO:0010817 187 0.023
nuclear import GO:0051170 35 0.023
regulation of secretion by cell GO:1903530 208 0.023
regulation of endopeptidase activity GO:0052548 51 0.023
Rat
female pregnancy GO:0007565 122 0.023
macromolecule localization GO:0033036 252 0.023
muscle cell differentiation GO:0042692 52 0.022
cellular cation homeostasis GO:0030003 180 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.022
kidney mesenchyme development GO:0072074 2 0.022
glial cell differentiation GO:0010001 65 0.022
regulation of body fluid levels GO:0050878 90 0.022
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 8 0.022

Smad1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.032