Rattus norvegicus

94 known processes

Smad2

SMAD family member 2

(Aliases: MGC156656,Madh2)

Smad2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to peptide GO:1901653 133 0.334
intracellular signal transduction GO:0035556 314 0.260
Human Rat
cellular response to endogenous stimulus GO:0071495 377 0.250
organelle organization GO:0006996 266 0.234
Rat
positive regulation of gene expression GO:0010628 244 0.212
negative regulation of macromolecule metabolic process GO:0010605 260 0.207
Human Rat
negative regulation of metabolic process GO:0009892 331 0.201
Human Rat
macromolecular complex subunit organization GO:0043933 339 0.197
Human Rat
transcription dna templated GO:0006351 377 0.164
response to peptide hormone GO:0043434 278 0.157
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.156
reproductive process GO:0022414 372 0.152
Rat
positive regulation of apoptotic process GO:0043065 154 0.143
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.141
regulation of cellular protein metabolic process GO:0032268 267 0.140
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.136
regulation of rna metabolic process GO:0051252 391 0.134
single organism biosynthetic process GO:0044711 342 0.127
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.126
macromolecule localization GO:0033036 252 0.124
programmed cell death GO:0012501 392 0.121
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.121
cellular response to organonitrogen compound GO:0071417 197 0.119
positive regulation of biosynthetic process GO:0009891 319 0.119
cellular response to nitrogen compound GO:1901699 210 0.115
regulation of rna biosynthetic process GO:2001141 381 0.113
response to peptide GO:1901652 292 0.109
macromolecular complex assembly GO:0065003 273 0.107
Human Rat
dephosphorylation GO:0016311 98 0.106
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.102
cell cycle GO:0007049 101 0.101
positive regulation of cellular biosynthetic process GO:0031328 295 0.094
protein complex subunit organization GO:0071822 302 0.094
Human Rat
protein complex biogenesis GO:0070271 263 0.092
Human Rat
positive regulation of cell death GO:0010942 184 0.092
Rat
positive regulation of transcription dna templated GO:0045893 197 0.090
single organism reproductive process GO:0044702 297 0.090
Rat
rna biosynthetic process GO:0032774 380 0.090
cellular component biogenesis GO:0044085 368 0.087
Human Rat
response to cytokine GO:0034097 215 0.087
regulation of cellular localization GO:0060341 263 0.086
positive regulation of cell differentiation GO:0045597 217 0.085
Rat
positive regulation of neurogenesis GO:0050769 165 0.085
Rat
regulation of molecular function GO:0065009 398 0.084
Rat
regulation of cellular component organization GO:0051128 368 0.082
Rat
rna metabolic process GO:0016070 406 0.081
positive regulation of rna metabolic process GO:0051254 203 0.081
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.080
Rat
protein transport GO:0015031 132 0.078
negative regulation of cellular biosynthetic process GO:0031327 161 0.078
Human Rat
protein oligomerization GO:0051259 191 0.078
regulation of nucleic acid templated transcription GO:1903506 380 0.077
cellular lipid metabolic process GO:0044255 208 0.076
regulation of anatomical structure morphogenesis GO:0022603 141 0.074
Rat
establishment of protein localization GO:0045184 141 0.073
cellular component assembly GO:0022607 360 0.071
Human Rat
negative regulation of multicellular organismal process GO:0051241 203 0.070
regulation of protein metabolic process GO:0051246 289 0.069
Rat
lipid metabolic process GO:0006629 283 0.069
positive regulation of cell communication GO:0010647 271 0.068
Human Rat
negative regulation of cellular metabolic process GO:0031324 281 0.067
Human Rat
sexual reproduction GO:0019953 148 0.066
negative regulation of biosynthetic process GO:0009890 168 0.066
Human Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.065
neurological system process GO:0050877 219 0.062
apoptotic process GO:0006915 381 0.062
Rat
single organism intracellular transport GO:1902582 166 0.061
regulation of transcription dna templated GO:0006355 374 0.061
regulation of cell differentiation GO:0045595 320 0.061
Rat
protein complex assembly GO:0006461 263 0.061
Human Rat
regulation of protein modification process GO:0031399 194 0.060
positive regulation of membrane potential GO:0045838 16 0.060
response to carbohydrate GO:0009743 183 0.059
regulation of response to stress GO:0080134 126 0.059
response to insulin GO:0032868 133 0.059
cellular response to oxygen containing compound GO:1901701 386 0.055
carbohydrate derivative metabolic process GO:1901135 346 0.054
regulation of neuron projection development GO:0010975 161 0.054
Rat
cellular response to insulin stimulus GO:0032869 81 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.054
cellular macromolecule localization GO:0070727 122 0.053
cellular protein localization GO:0034613 122 0.053
cell cycle phase transition GO:0044770 21 0.052
secretion GO:0046903 307 0.052
dendrite development GO:0016358 72 0.052
Rat
protein localization GO:0008104 191 0.051
regulation of cell development GO:0060284 263 0.051
Rat
secretion by cell GO:0032940 248 0.051
cell morphogenesis involved in differentiation GO:0000904 119 0.051
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.050
carboxylic acid metabolic process GO:0019752 289 0.050
negative regulation of rna metabolic process GO:0051253 123 0.048
Human Rat
positive regulation of response to external stimulus GO:0032103 51 0.048
Rat
positive regulation of interleukin 1 beta production GO:0032731 6 0.048
Rat
multi organism reproductive process GO:0044703 262 0.048
cation transport GO:0006812 382 0.048
cellular ketone metabolic process GO:0042180 51 0.047
protein targeting GO:0006605 61 0.047
cellular response to hormone stimulus GO:0032870 247 0.047
metal ion transport GO:0030001 289 0.047
mitotic cell cycle GO:0000278 49 0.047
enzyme linked receptor protein signaling pathway GO:0007167 116 0.046
positive regulation of signaling GO:0023056 270 0.046
Human Rat
negative regulation of developmental process GO:0051093 125 0.046
actin filament based process GO:0030029 86 0.044
Rat
organic substance catabolic process GO:1901575 316 0.044
regulation of lipid metabolic process GO:0019216 68 0.043
cellular response to organic cyclic compound GO:0071407 202 0.043
negative regulation of cell proliferation GO:0008285 119 0.043
intracellular protein transport GO:0006886 79 0.043
mapk cascade GO:0000165 140 0.043
Rat
neuron projection morphogenesis GO:0048812 122 0.043
Rat
brain development GO:0007420 247 0.042
negative regulation of protein metabolic process GO:0051248 114 0.042
chromosome segregation GO:0007059 2 0.042
organophosphate metabolic process GO:0019637 370 0.042
positive regulation of neuron differentiation GO:0045666 126 0.042
Rat
protein localization to organelle GO:0033365 57 0.041
reproduction GO:0000003 245 0.041
activation of cysteine type endopeptidase activity GO:0097202 4 0.041
Rat
catabolic process GO:0009056 351 0.041
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.041
Human Rat
cellular amino acid metabolic process GO:0006520 107 0.041
neuron projection development GO:0031175 273 0.040
Rat
positive regulation of cell projection organization GO:0031346 111 0.040
Rat
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.040
response to oxygen levels GO:0070482 265 0.040
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
cell cycle g1 s phase transition GO:0044843 13 0.040
response to toxic substance GO:0009636 133 0.039
regulation of neurogenesis GO:0050767 247 0.038
Rat
regulation of programmed cell death GO:0043067 341 0.038
Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.038
oxoacid metabolic process GO:0043436 290 0.038
regulation of apoptotic process GO:0042981 335 0.038
Rat
negative regulation of signaling GO:0023057 157 0.038
positive regulation of cellular component organization GO:0051130 200 0.037
Rat
negative regulation of transcription dna templated GO:0045892 116 0.037
Human Rat
multicellular organismal reproductive process GO:0048609 233 0.037
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.037
Rat
central nervous system development GO:0007417 311 0.036
regulation of secretion by cell GO:1903530 208 0.036
positive regulation of protein phosphorylation GO:0001934 135 0.036
neuron differentiation GO:0030182 368 0.036
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.036
Human Rat
regulation of phosphorus metabolic process GO:0051174 349 0.036
Rat
gland development GO:0048732 155 0.035
cell cycle process GO:0022402 57 0.035
negative regulation of response to stimulus GO:0048585 155 0.035
response to ethanol GO:0045471 162 0.035
intracellular transport GO:0046907 185 0.034
developmental process involved in reproduction GO:0003006 159 0.034
Rat
regulation of signal transduction GO:0009966 318 0.034
Human Rat
forebrain development GO:0030900 98 0.034
protein phosphorylation GO:0006468 345 0.034
Human
regulation of intracellular signal transduction GO:1902531 218 0.033
nucleic acid templated transcription GO:0097659 379 0.033
response to hexose GO:0009746 144 0.033
cell projection organization GO:0030030 302 0.033
Rat
positive regulation of intracellular protein transport GO:0090316 20 0.033
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
Rat
protein targeting to nucleus GO:0044744 35 0.033
cellular response to stress GO:0033554 269 0.033
positive regulation of cell development GO:0010720 176 0.032
Rat
regulation of phosphate metabolic process GO:0019220 349 0.032
Rat
circadian rhythm GO:0007623 88 0.032
head development GO:0060322 247 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
Human Rat
mitotic cell cycle phase transition GO:0044772 20 0.031
response to corticosteroid GO:0031960 235 0.031
neuron development GO:0048666 286 0.031
Rat
spermatogenesis GO:0007283 99 0.031
response to inorganic substance GO:0010035 377 0.030
amine metabolic process GO:0009308 38 0.030
regulation of cell morphogenesis GO:0022604 77 0.030
Rat
carbohydrate metabolic process GO:0005975 130 0.030
negative regulation of apoptotic process GO:0043066 181 0.030
Rat
organophosphate biosynthetic process GO:0090407 143 0.030
negative regulation of gene expression GO:0010629 199 0.030
Human Rat
positive regulation of developmental process GO:0051094 283 0.030
Human Rat
response to amino acid GO:0043200 75 0.030
regulation of phosphorylation GO:0042325 248 0.030
positive regulation of programmed cell death GO:0043068 157 0.029
Rat
positive regulation of protein modification process GO:0031401 142 0.029
dendrite morphogenesis GO:0048813 43 0.029
Rat
lipid biosynthetic process GO:0008610 128 0.029
gamete generation GO:0007276 124 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
single organism catabolic process GO:0044712 283 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
positive regulation of neuron projection development GO:0010976 99 0.028
Rat
response to decreased oxygen levels GO:0036293 237 0.028
Rat
reactive oxygen species biosynthetic process GO:1903409 8 0.028
negative regulation of cellular protein metabolic process GO:0032269 106 0.028
positive regulation of response to stimulus GO:0048584 285 0.028
Human Rat
purine nucleotide metabolic process GO:0006163 229 0.028
response to testosterone GO:0033574 55 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
Human Rat
response to purine containing compound GO:0014074 126 0.027
cognition GO:0050890 92 0.027
response to ketone GO:1901654 182 0.027
male mating behavior GO:0060179 3 0.027
somatic stem cell division GO:0048103 2 0.027
regulation of establishment of protein localization GO:0070201 69 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
Rat
cellular amine metabolic process GO:0044106 38 0.026
divalent metal ion transport GO:0070838 132 0.026
cell projection morphogenesis GO:0048858 123 0.026
Rat
aging GO:0007568 241 0.026
regulation of cell projection organization GO:0031344 175 0.026
Rat
chromatin assembly or disassembly GO:0006333 1 0.026
g1 s transition of mitotic cell cycle GO:0000082 12 0.026
eye morphogenesis GO:0048592 4 0.026
regulation of kinase activity GO:0043549 117 0.025
reactive nitrogen species metabolic process GO:2001057 1 0.025
response to glucose GO:0009749 136 0.025
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
protein processing GO:0016485 68 0.025
Rat
cytoplasmic transport GO:0016482 115 0.025
cell cell signaling GO:0007267 335 0.024
asymmetric stem cell division GO:0098722 2 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.024
Human Rat
cellular response to cytokine stimulus GO:0071345 127 0.024
purine containing compound metabolic process GO:0072521 253 0.024
regulation of neuron apoptotic process GO:0043523 83 0.024
regulation of hydrolase activity GO:0051336 143 0.024
Rat
limbic system development GO:0021761 38 0.024
homeostatic process GO:0042592 331 0.024
negative regulation of transport GO:0051051 136 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.024
Rat
synaptic transmission GO:0007268 235 0.024
single organism organelle organization GO:1902589 180 0.023
Rat
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.023
Rat
regulation of nervous system development GO:0051960 264 0.023
Rat
response to acid chemical GO:0001101 222 0.023
response to antibiotic GO:0046677 39 0.023
mitotic cell cycle process GO:1903047 35 0.023
cell type specific apoptotic process GO:0097285 134 0.023
Rat
cellular response to lipid GO:0071396 201 0.023
regulation of protein localization GO:0032880 81 0.023
cellular macromolecular complex assembly GO:0034622 58 0.023
Human Rat
protein heterooligomerization GO:0051291 89 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
Human Rat
actin cytoskeleton organization GO:0030036 73 0.022
Rat
ribose phosphate metabolic process GO:0019693 235 0.022
positive regulation of signal transduction GO:0009967 175 0.022
Human Rat
regulation of cell migration GO:0030334 128 0.022
Rat
calcium ion transport GO:0006816 131 0.022
cell fate determination GO:0001709 2 0.022
regeneration GO:0031099 163 0.022
tissue development GO:0009888 252 0.022
Human Rat
nuclear transport GO:0051169 49 0.022
response to alkaloid GO:0043279 132 0.022
transmembrane transport GO:0055085 412 0.021
protein homooligomerization GO:0051260 91 0.021
negative regulation of signal transduction GO:0009968 83 0.021
cellular component morphogenesis GO:0032989 155 0.021
Rat
rhythmic process GO:0048511 156 0.021
neuromuscular synaptic transmission GO:0007274 2 0.021
male gamete generation GO:0048232 99 0.021
regulation of secretion GO:0051046 224 0.021
cellular response to growth factor stimulus GO:0071363 162 0.020
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 3 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.020
neuron apoptotic process GO:0051402 88 0.020
immune system process GO:0002376 204 0.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.020
ribonucleotide metabolic process GO:0009259 231 0.019
regulation of developmental growth GO:0048638 45 0.019
translation GO:0006412 35 0.019
memory GO:0007613 54 0.019
regulation of catalytic activity GO:0050790 304 0.019
Rat
inflammatory response GO:0006954 150 0.019
response to estrogen GO:0043627 232 0.019
Rat
erythrocyte homeostasis GO:0034101 2 0.019
positive regulation of transcription factor import into nucleus GO:0042993 4 0.019
organic hydroxy compound metabolic process GO:1901615 115 0.019
organophosphate catabolic process GO:0046434 148 0.019
growth GO:0040007 165 0.019
positive regulation of dendrite morphogenesis GO:0050775 21 0.019
Rat
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.019
Human Rat
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.019
Rat
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.019
response to hydrogen peroxide GO:0042542 89 0.018
negative regulation of cell death GO:0060548 229 0.018
Rat
negative regulation of cell cycle phase transition GO:1901988 4 0.018
response to hypoxia GO:0001666 231 0.018
Rat
response to monosaccharide GO:0034284 159 0.018
establishment of protein localization to organelle GO:0072594 44 0.018
peptidyl amino acid modification GO:0018193 126 0.018
wound healing GO:0042060 122 0.018
Rat
regulation of cell cycle GO:0051726 73 0.018
regulation of mapk cascade GO:0043408 116 0.018
heart contraction GO:0060047 57 0.018
regulation of ion transport GO:0043269 245 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
embryonic pattern specification GO:0009880 1 0.018
Human
regulation of endopeptidase activity GO:0052548 51 0.018
Rat
response to glucocorticoid GO:0051384 223 0.018
cytoskeleton organization GO:0007010 111 0.018
Rat
multicellular organism reproduction GO:0032504 233 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
cellular catabolic process GO:0044248 295 0.018
small molecule catabolic process GO:0044282 59 0.018
centrosome organization GO:0051297 1 0.017
response to tumor necrosis factor GO:0034612 56 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
Rat
signal transduction by phosphorylation GO:0023014 144 0.017
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.017
transmission of nerve impulse GO:0019226 42 0.017
response to wounding GO:0009611 254 0.017
Rat
regulation of retinal cell programmed cell death GO:0046668 1 0.017
locomotion GO:0040011 237 0.017
Rat
nucleotide metabolic process GO:0009117 279 0.017
protein secretion GO:0009306 34 0.017
regulation of cell proliferation GO:0042127 359 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
ion transmembrane transport GO:0034220 365 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
regulation of smooth muscle cell proliferation GO:0048660 75 0.017
regulation of transferase activity GO:0051338 123 0.017
regulation of cellular response to stress GO:0080135 49 0.017
negative regulation of cell communication GO:0010648 158 0.016
regulation of protein kinase activity GO:0045859 105 0.016
sensory organ development GO:0007423 74 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
ras protein signal transduction GO:0007265 29 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.016
Rat
cardiac ventricle development GO:0003231 1 0.016
divalent inorganic cation transport GO:0072511 134 0.016
regulation of cytokine production GO:0001817 56 0.016
Rat
chemical homeostasis GO:0048878 292 0.016
response to other organism GO:0051707 220 0.016
single organism behavior GO:0044708 130 0.016
response to nutrient GO:0007584 248 0.016
response to reactive oxygen species GO:0000302 120 0.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.015
Rat
gastrulation GO:0007369 2 0.015
embryonic axis specification GO:0000578 1 0.015
Human
regulation of response to external stimulus GO:0032101 106 0.015
Rat
vesicle mediated transport GO:0016192 181 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.015
circulatory system development GO:0072359 134 0.015
steroid biosynthetic process GO:0006694 48 0.015
digestive tract development GO:0048565 39 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
Human Rat
blood circulation GO:0008015 183 0.015
neuron death GO:0070997 127 0.015
motor neuron axon guidance GO:0008045 1 0.015
nucleotide biosynthetic process GO:0009165 98 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
Rat
response to heat GO:0009408 60 0.015
regulation of system process GO:0044057 208 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
nitrogen compound transport GO:0071705 229 0.015
erythrocyte differentiation GO:0030218 1 0.015
retinal cell programmed cell death GO:0046666 1 0.014
regulation of hormone levels GO:0010817 187 0.014
positive regulation of interleukin 1 secretion GO:0050716 3 0.014
regulation of protein transport GO:0051223 68 0.014
stem cell division GO:0017145 4 0.014
regulation of cellular component movement GO:0051270 150 0.014
Rat
response to temperature stimulus GO:0009266 94 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
cell motility GO:0048870 202 0.014
Rat
syncytium formation GO:0006949 4 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
regulation of growth GO:0040008 105 0.014
posttranscriptional regulation of gene expression GO:0010608 37 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
hair cycle process GO:0022405 2 0.014
cell growth GO:0016049 104 0.014
cellular response to alcohol GO:0097306 87 0.014
response to nutrient levels GO:0031667 370 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
Rat
positive regulation of dendrite development GO:1900006 35 0.014
Rat
cardiac chamber development GO:0003205 1 0.014
positive regulation of molecular function GO:0044093 230 0.014
Rat
positive regulation of phosphorylation GO:0042327 177 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.014
muscle system process GO:0003012 115 0.014
organic acid metabolic process GO:0006082 292 0.014
phospholipid metabolic process GO:0006644 61 0.014
muscle structure development GO:0061061 87 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
Rat
lipid transport GO:0006869 61 0.014
multicellular organism growth GO:0035264 1 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
single organism membrane organization GO:0044802 74 0.013
multicellular organismal signaling GO:0035637 44 0.013
organ morphogenesis GO:0009887 75 0.013
learning or memory GO:0007611 90 0.013
nucleoside metabolic process GO:0009116 179 0.013
luteolysis GO:0001554 5 0.013
response to mechanical stimulus GO:0009612 134 0.013
protein autophosphorylation GO:0046777 66 0.013
response to growth factor GO:0070848 189 0.013
regulation of gluconeogenesis GO:0006111 4 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
positive regulation of transferase activity GO:0051347 81 0.013
defense response GO:0006952 194 0.013
interleukin 12 production GO:0032615 3 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
nucleosome organization GO:0034728 1 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
protein localization to nucleus GO:0034504 39 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
Human Rat
cellular protein complex assembly GO:0043623 44 0.013
Human Rat
neuronal action potential GO:0019228 35 0.013
cell cycle checkpoint GO:0000075 2 0.013
cation transmembrane transport GO:0098655 263 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
Rat
regulation of neuron differentiation GO:0045664 208 0.013
Rat
regulation of intracellular protein transport GO:0033157 34 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.013
regulation of membrane potential GO:0042391 110 0.012
developmental growth GO:0048589 100 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
hormone secretion GO:0046879 115 0.012
bmp signaling pathway GO:0030509 4 0.012
Human Rat
intracellular receptor signaling pathway GO:0030522 35 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
liver development GO:0001889 90 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 28 0.012
regulation of embryonic development GO:0045995 2 0.012
positive regulation of secretion GO:0051047 140 0.012
heart process GO:0003015 57 0.012
response to retinoic acid GO:0032526 63 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
cytokine mediated signaling pathway GO:0019221 43 0.012
calcium ion homeostasis GO:0055074 162 0.012
cytokine production GO:0001816 61 0.012
Rat
regulation of intracellular transport GO:0032386 65 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
response to metal ion GO:0010038 253 0.012
innate immune response GO:0045087 35 0.012
cell morphogenesis GO:0000902 142 0.012
Rat
negative regulation of intracellular signal transduction GO:1902532 38 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
glycerolipid metabolic process GO:0046486 67 0.012
aromatic compound catabolic process GO:0019439 168 0.012
response to molecule of bacterial origin GO:0002237 194 0.011
nucleotide catabolic process GO:0009166 139 0.011
regulation of muscle system process GO:0090257 79 0.011
regulation of microtubule cytoskeleton organization GO:0070507 14 0.011
cellular homeostasis GO:0019725 252 0.011
cell adhesion GO:0007155 110 0.011
Rat
alcohol metabolic process GO:0006066 77 0.011
sex differentiation GO:0007548 113 0.011
Rat
heterocycle catabolic process GO:0046700 167 0.011
negative regulation of secretion GO:0051048 82 0.011
localization of cell GO:0051674 202 0.011
Rat
neuron fate commitment GO:0048663 4 0.011
action potential GO:0001508 54 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
Rat
membrane organization GO:0061024 94 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
regulation of anatomical structure size GO:0090066 135 0.011
molting cycle process GO:0022404 2 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
Human
positive regulation of protein transport GO:0051222 41 0.011
cardiovascular system development GO:0072358 134 0.011
interleukin 1 beta secretion GO:0050702 3 0.011
neuronal stem cell division GO:0036445 1 0.011
regulation of cysteine type endopeptidase activity GO:2000116 32 0.011
Rat
molting cycle GO:0042303 3 0.011
negative regulation of cell development GO:0010721 82 0.011
positive regulation of organelle organization GO:0010638 48 0.011
Rat
regulation of blood circulation GO:1903522 110 0.011
signal release GO:0023061 145 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.010
regulation of peptidase activity GO:0052547 55 0.010
Rat
positive regulation of secretion by cell GO:1903532 128 0.010
adult locomotory behavior GO:0008344 4 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
response to lipopolysaccharide GO:0032496 191 0.010
behavior GO:0007610 205 0.010
Rat
pigment biosynthetic process GO:0046148 4 0.010
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.010
Rat

Smad2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
central nervous system disease DOID:331 0 0.012