Rattus norvegicus

94 known processes

Smad2

SMAD family member 2

(Aliases: MGC156656,Madh2)

Smad2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to peptide GO:1901653 133 0.334
intracellular signal transduction GO:0035556 314 0.260
Human Rat
cellular response to endogenous stimulus GO:0071495 377 0.250
organelle organization GO:0006996 266 0.234
Rat
positive regulation of gene expression GO:0010628 244 0.212
negative regulation of macromolecule metabolic process GO:0010605 260 0.207
Human Rat
negative regulation of metabolic process GO:0009892 331 0.201
Human Rat
macromolecular complex subunit organization GO:0043933 339 0.197
Human Rat
transcription dna templated GO:0006351 377 0.164
response to peptide hormone GO:0043434 278 0.157
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.156
reproductive process GO:0022414 372 0.152
Rat
positive regulation of apoptotic process GO:0043065 154 0.143
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.141
regulation of cellular protein metabolic process GO:0032268 267 0.140
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.136
regulation of rna metabolic process GO:0051252 391 0.134
single organism biosynthetic process GO:0044711 342 0.127
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.126
macromolecule localization GO:0033036 252 0.124
programmed cell death GO:0012501 392 0.121
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.121
cellular response to organonitrogen compound GO:0071417 197 0.119
positive regulation of biosynthetic process GO:0009891 319 0.119
cellular response to nitrogen compound GO:1901699 210 0.115
regulation of rna biosynthetic process GO:2001141 381 0.113
response to peptide GO:1901652 292 0.109
macromolecular complex assembly GO:0065003 273 0.107
Human Rat
dephosphorylation GO:0016311 98 0.106
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.102
cell cycle GO:0007049 101 0.101
positive regulation of cellular biosynthetic process GO:0031328 295 0.094
protein complex subunit organization GO:0071822 302 0.094
Human Rat
protein complex biogenesis GO:0070271 263 0.092
Human Rat
positive regulation of cell death GO:0010942 184 0.092
Rat
positive regulation of transcription dna templated GO:0045893 197 0.090
single organism reproductive process GO:0044702 297 0.090
Rat
rna biosynthetic process GO:0032774 380 0.090
cellular component biogenesis GO:0044085 368 0.087
Human Rat
response to cytokine GO:0034097 215 0.087
regulation of cellular localization GO:0060341 263 0.086
positive regulation of cell differentiation GO:0045597 217 0.085
Rat
positive regulation of neurogenesis GO:0050769 165 0.085
Rat
regulation of molecular function GO:0065009 398 0.084
Rat
regulation of cellular component organization GO:0051128 368 0.082
Rat
rna metabolic process GO:0016070 406 0.081
positive regulation of rna metabolic process GO:0051254 203 0.081
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.080
Rat
protein transport GO:0015031 132 0.078
negative regulation of cellular biosynthetic process GO:0031327 161 0.078
Human Rat
protein oligomerization GO:0051259 191 0.078
regulation of nucleic acid templated transcription GO:1903506 380 0.077
cellular lipid metabolic process GO:0044255 208 0.076
regulation of anatomical structure morphogenesis GO:0022603 141 0.074
Rat
establishment of protein localization GO:0045184 141 0.073
cellular component assembly GO:0022607 360 0.071
Human Rat
negative regulation of multicellular organismal process GO:0051241 203 0.070
regulation of protein metabolic process GO:0051246 289 0.069
Rat
lipid metabolic process GO:0006629 283 0.069
positive regulation of cell communication GO:0010647 271 0.068
Human Rat
negative regulation of cellular metabolic process GO:0031324 281 0.067
Human Rat
sexual reproduction GO:0019953 148 0.066
negative regulation of biosynthetic process GO:0009890 168 0.066
Human Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.065
neurological system process GO:0050877 219 0.062
apoptotic process GO:0006915 381 0.062
Rat
single organism intracellular transport GO:1902582 166 0.061
regulation of transcription dna templated GO:0006355 374 0.061
regulation of cell differentiation GO:0045595 320 0.061
Rat
protein complex assembly GO:0006461 263 0.061
Human Rat
regulation of protein modification process GO:0031399 194 0.060
positive regulation of membrane potential GO:0045838 16 0.060
response to carbohydrate GO:0009743 183 0.059
regulation of response to stress GO:0080134 126 0.059
response to insulin GO:0032868 133 0.059
cellular response to oxygen containing compound GO:1901701 386 0.055
carbohydrate derivative metabolic process GO:1901135 346 0.054
regulation of neuron projection development GO:0010975 161 0.054
Rat
cellular response to insulin stimulus GO:0032869 81 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.054
cellular macromolecule localization GO:0070727 122 0.053
cellular protein localization GO:0034613 122 0.053
cell cycle phase transition GO:0044770 21 0.052
secretion GO:0046903 307 0.052
dendrite development GO:0016358 72 0.052
Rat
protein localization GO:0008104 191 0.051
regulation of cell development GO:0060284 263 0.051
Rat
secretion by cell GO:0032940 248 0.051
cell morphogenesis involved in differentiation GO:0000904 119 0.051
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.050
carboxylic acid metabolic process GO:0019752 289 0.050
negative regulation of rna metabolic process GO:0051253 123 0.048
Human Rat
positive regulation of response to external stimulus GO:0032103 51 0.048
Rat
positive regulation of interleukin 1 beta production GO:0032731 6 0.048
Rat
multi organism reproductive process GO:0044703 262 0.048
cation transport GO:0006812 382 0.048
cellular ketone metabolic process GO:0042180 51 0.047
protein targeting GO:0006605 61 0.047
cellular response to hormone stimulus GO:0032870 247 0.047
metal ion transport GO:0030001 289 0.047
mitotic cell cycle GO:0000278 49 0.047
enzyme linked receptor protein signaling pathway GO:0007167 116 0.046
positive regulation of signaling GO:0023056 270 0.046
Human Rat
negative regulation of developmental process GO:0051093 125 0.046
actin filament based process GO:0030029 86 0.044
Rat
organic substance catabolic process GO:1901575 316 0.044
regulation of lipid metabolic process GO:0019216 68 0.043
cellular response to organic cyclic compound GO:0071407 202 0.043
negative regulation of cell proliferation GO:0008285 119 0.043
intracellular protein transport GO:0006886 79 0.043
mapk cascade GO:0000165 140 0.043
Rat
neuron projection morphogenesis GO:0048812 122 0.043
Rat
brain development GO:0007420 247 0.042
negative regulation of protein metabolic process GO:0051248 114 0.042
chromosome segregation GO:0007059 2 0.042
organophosphate metabolic process GO:0019637 370 0.042
positive regulation of neuron differentiation GO:0045666 126 0.042
Rat
protein localization to organelle GO:0033365 57 0.041
reproduction GO:0000003 245 0.041
activation of cysteine type endopeptidase activity GO:0097202 4 0.041
Rat
catabolic process GO:0009056 351 0.041
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.041
Human Rat
cellular amino acid metabolic process GO:0006520 107 0.041
neuron projection development GO:0031175 273 0.040
Rat
positive regulation of cell projection organization GO:0031346 111 0.040
Rat
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.040
response to oxygen levels GO:0070482 265 0.040
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
cell cycle g1 s phase transition GO:0044843 13 0.040
response to toxic substance GO:0009636 133 0.039
regulation of neurogenesis GO:0050767 247 0.038
Rat
regulation of programmed cell death GO:0043067 341 0.038
Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.038
oxoacid metabolic process GO:0043436 290 0.038
regulation of apoptotic process GO:0042981 335 0.038
Rat
negative regulation of signaling GO:0023057 157 0.038
positive regulation of cellular component organization GO:0051130 200 0.037
Rat
negative regulation of transcription dna templated GO:0045892 116 0.037
Human Rat
multicellular organismal reproductive process GO:0048609 233 0.037
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.037
Rat
central nervous system development GO:0007417 311 0.036
regulation of secretion by cell GO:1903530 208 0.036
positive regulation of protein phosphorylation GO:0001934 135 0.036
neuron differentiation GO:0030182 368 0.036
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.036
Human Rat
regulation of phosphorus metabolic process GO:0051174 349 0.036
Rat
gland development GO:0048732 155 0.035
cell cycle process GO:0022402 57 0.035
negative regulation of response to stimulus GO:0048585 155 0.035
response to ethanol GO:0045471 162 0.035
intracellular transport GO:0046907 185 0.034
developmental process involved in reproduction GO:0003006 159 0.034
Rat
regulation of signal transduction GO:0009966 318 0.034
Human Rat
forebrain development GO:0030900 98 0.034
protein phosphorylation GO:0006468 345 0.034
Human
regulation of intracellular signal transduction GO:1902531 218 0.033
nucleic acid templated transcription GO:0097659 379 0.033
response to hexose GO:0009746 144 0.033
cell projection organization GO:0030030 302 0.033
Rat
positive regulation of intracellular protein transport GO:0090316 20 0.033
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
Rat
protein targeting to nucleus GO:0044744 35 0.033
cellular response to stress GO:0033554 269 0.033
positive regulation of cell development GO:0010720 176 0.032
Rat
regulation of phosphate metabolic process GO:0019220 349 0.032
Rat
circadian rhythm GO:0007623 88 0.032
head development GO:0060322 247 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
Human Rat
mitotic cell cycle phase transition GO:0044772 20 0.031
response to corticosteroid GO:0031960 235 0.031
neuron development GO:0048666 286 0.031
Rat
spermatogenesis GO:0007283 99 0.031
response to inorganic substance GO:0010035 377 0.030
amine metabolic process GO:0009308 38 0.030
regulation of cell morphogenesis GO:0022604 77 0.030
Rat
carbohydrate metabolic process GO:0005975 130 0.030
negative regulation of apoptotic process GO:0043066 181 0.030
Rat
organophosphate biosynthetic process GO:0090407 143 0.030
negative regulation of gene expression GO:0010629 199 0.030
Human Rat
positive regulation of developmental process GO:0051094 283 0.030
Human Rat
response to amino acid GO:0043200 75 0.030
regulation of phosphorylation GO:0042325 248 0.030
positive regulation of programmed cell death GO:0043068 157 0.029
Rat
positive regulation of protein modification process GO:0031401 142 0.029
dendrite morphogenesis GO:0048813 43 0.029
Rat
lipid biosynthetic process GO:0008610 128 0.029
gamete generation GO:0007276 124 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
single organism catabolic process GO:0044712 283 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
positive regulation of neuron projection development GO:0010976 99 0.028
Rat
response to decreased oxygen levels GO:0036293 237 0.028
Rat
reactive oxygen species biosynthetic process GO:1903409 8 0.028
negative regulation of cellular protein metabolic process GO:0032269 106 0.028
positive regulation of response to stimulus GO:0048584 285 0.028
Human Rat
purine nucleotide metabolic process GO:0006163 229 0.028
response to testosterone GO:0033574 55 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
Human Rat
response to purine containing compound GO:0014074 126 0.027
cognition GO:0050890 92 0.027
response to ketone GO:1901654 182 0.027
male mating behavior GO:0060179 3 0.027
somatic stem cell division GO:0048103 2 0.027
regulation of establishment of protein localization GO:0070201 69 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
Rat
cellular amine metabolic process GO:0044106 38 0.026
divalent metal ion transport GO:0070838 132 0.026
cell projection morphogenesis GO:0048858 123 0.026
Rat
aging GO:0007568 241 0.026
regulation of cell projection organization GO:0031344 175 0.026
Rat
chromatin assembly or disassembly GO:0006333 1 0.026
g1 s transition of mitotic cell cycle GO:0000082 12 0.026
eye morphogenesis GO:0048592 4 0.026
regulation of kinase activity GO:0043549 117 0.025
reactive nitrogen species metabolic process GO:2001057 1 0.025
response to glucose GO:0009749 136 0.025
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
protein processing GO:0016485 68 0.025
Rat
cytoplasmic transport GO:0016482 115 0.025
cell cell signaling GO:0007267 335 0.024
asymmetric stem cell division GO:0098722 2 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.024
Human Rat
cellular response to cytokine stimulus GO:0071345 127 0.024
purine containing compound metabolic process GO:0072521 253 0.024
regulation of neuron apoptotic process GO:0043523 83 0.024
regulation of hydrolase activity GO:0051336 143 0.024
Rat
limbic system development GO:0021761 38 0.024
homeostatic process GO:0042592 331 0.024
negative regulation of transport GO:0051051 136 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.024
Rat
synaptic transmission GO:0007268 235 0.024
single organism organelle organization GO:1902589 180 0.023
Rat
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.023
Rat
regulation of nervous system development GO:0051960 264 0.023
Rat
response to acid chemical GO:0001101 222 0.023
response to antibiotic GO:0046677 39 0.023
mitotic cell cycle process GO:1903047 35 0.023
cell type specific apoptotic process GO:0097285 134 0.023
Rat
cellular response to lipid GO:0071396 201 0.023
regulation of protein localization GO:0032880 81 0.023
cellular macromolecular complex assembly GO:0034622 58 0.023
Human Rat
protein heterooligomerization GO:0051291 89 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
Human Rat
actin cytoskeleton organization GO:0030036 73 0.022
Rat
ribose phosphate metabolic process GO:0019693 235 0.022
positive regulation of signal transduction GO:0009967 175 0.022
Human Rat
regulation of cell migration GO:0030334 128 0.022
Rat
calcium ion transport GO:0006816 131 0.022
cell fate determination GO:0001709 2 0.022
regeneration GO:0031099 163 0.022
tissue development GO:0009888 252 0.022
Human Rat
nuclear transport GO:0051169 49 0.022
response to alkaloid GO:0043279 132 0.022
transmembrane transport GO:0055085 412 0.021
protein homooligomerization GO:0051260 91 0.021
negative regulation of signal transduction GO:0009968 83 0.021
cellular component morphogenesis GO:0032989 155 0.021
Rat
rhythmic process GO:0048511 156 0.021
neuromuscular synaptic transmission GO:0007274 2 0.021
male gamete generation GO:0048232 99 0.021
regulation of secretion GO:0051046 224 0.021
cellular response to growth factor stimulus GO:0071363 162 0.020
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 3 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.020
neuron apoptotic process GO:0051402 88 0.020
immune system process GO:0002376 204 0.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.020
ribonucleotide metabolic process GO:0009259 231 0.019
regulation of developmental growth GO:0048638 45 0.019
translation GO:0006412 35 0.019
memory GO:0007613 54 0.019
regulation of catalytic activity GO:0050790 304 0.019
Rat
inflammatory response GO:0006954 150 0.019
response to estrogen GO:0043627 232 0.019
Rat
erythrocyte homeostasis GO:0034101 2 0.019
positive regulation of transcription factor import into nucleus GO:0042993 4 0.019
organic hydroxy compound metabolic process GO:1901615 115 0.019
organophosphate catabolic process GO:0046434 148 0.019
growth GO:0040007 165 0.019
positive regulation of dendrite morphogenesis GO:0050775 21 0.019
Rat
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.019
Human Rat
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.019
Rat
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.019
response to hydrogen peroxide GO:0042542 89 0.018
negative regulation of cell death GO:0060548 229 0.018
Rat
negative regulation of cell cycle phase transition GO:1901988 4 0.018
response to hypoxia GO:0001666 231 0.018
Rat
response to monosaccharide GO:0034284 159 0.018
establishment of protein localization to organelle GO:0072594 44 0.018
peptidyl amino acid modification GO:0018193 126 0.018
wound healing GO:0042060 122 0.018
Rat
regulation of cell cycle GO:0051726 73 0.018
regulation of mapk cascade GO:0043408 116 0.018
heart contraction GO:0060047 57 0.018
regulation of ion transport GO:0043269 245 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
embryonic pattern specification GO:0009880 1 0.018
Human
regulation of endopeptidase activity GO:0052548 51 0.018
Rat
response to glucocorticoid GO:0051384 223 0.018
cytoskeleton organization GO:0007010 111 0.018
Rat
multicellular organism reproduction GO:0032504 233 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
cellular catabolic process GO:0044248 295 0.018
small molecule catabolic process GO:0044282 59 0.018
centrosome organization GO:0051297 1 0.017
response to tumor necrosis factor GO:0034612 56 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
Rat
signal transduction by phosphorylation GO:0023014 144 0.017
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.017
transmission of nerve impulse GO:0019226 42 0.017
response to wounding GO:0009611 254 0.017
Rat
regulation of retinal cell programmed cell death GO:0046668 1 0.017
locomotion GO:0040011 237 0.017
Rat
nucleotide metabolic process GO:0009117 279 0.017
protein secretion GO:0009306 34 0.017
regulation of cell proliferation GO:0042127 359 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
ion transmembrane transport GO:0034220 365 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
regulation of smooth muscle cell proliferation GO:0048660 75 0.017
regulation of transferase activity GO:0051338 123 0.017
regulation of cellular response to stress GO:0080135 49 0.017
negative regulation of cell communication GO:0010648 158 0.016
regulation of protein kinase activity GO:0045859 105 0.016
sensory organ development GO:0007423 74 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
ras protein signal transduction GO:0007265 29 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.016
Rat
cardiac ventricle development GO:0003231 1 0.016
divalent inorganic cation transport GO:0072511 134 0.016
regulation of cytokine production GO:0001817 56 0.016
Rat
chemical homeostasis GO:0048878 292 0.016
response to other organism GO:0051707 220 0.016
single organism behavior GO:0044708 130 0.016
response to nutrient GO:0007584 248 0.016
response to reactive oxygen species GO:0000302 120 0.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.015
Rat
gastrulation GO:0007369 2 0.015
embryonic axis specification GO:0000578 1 0.015
Human
regulation of response to external stimulus GO:0032101 106 0.015
Rat
vesicle mediated transport GO:0016192 181 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.015
circulatory system development GO:0072359 134 0.015
steroid biosynthetic process GO:0006694 48 0.015
digestive tract development GO:0048565 39 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
Human Rat
blood circulation GO:0008015 183 0.015
neuron death GO:0070997 127 0.015
motor neuron axon guidance GO:0008045 1 0.015
nucleotide biosynthetic process GO:0009165 98 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
Rat
response to heat GO:0009408 60 0.015
regulation of system process GO:0044057 208 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
nitrogen compound transport GO:0071705 229 0.015
erythrocyte differentiation GO:0030218 1 0.015
retinal cell programmed cell death GO:0046666 1 0.014
regulation of hormone levels GO:0010817 187 0.014
positive regulation of interleukin 1 secretion GO:0050716 3 0.014
regulation of protein transport GO:0051223 68 0.014
stem cell division GO:0017145 4 0.014
regulation of cellular component movement GO:0051270 150 0.014
Rat
response to temperature stimulus GO:0009266 94 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
cell motility GO:0048870 202 0.014
Rat
syncytium formation GO:0006949 4 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
regulation of growth GO:0040008 105 0.014
posttranscriptional regulation of gene expression GO:0010608 37 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
hair cycle process GO:0022405 2 0.014
cell growth GO:0016049 104 0.014
cellular response to alcohol GO:0097306 87 0.014
response to nutrient levels GO:0031667 370 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
Rat
positive regulation of dendrite development GO:1900006 35 0.014
Rat
cardiac chamber development GO:0003205 1 0.014
positive regulation of molecular function GO:0044093 230 0.014
Rat
positive regulation of phosphorylation GO:0042327 177 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.014
muscle system process GO:0003012 115 0.014
organic acid metabolic process GO:0006082 292 0.014
phospholipid metabolic process GO:0006644 61 0.014
muscle structure development GO:0061061 87 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
Rat
lipid transport GO:0006869 61 0.014
multicellular organism growth GO:0035264 1 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
single organism membrane organization GO:0044802 74 0.013
multicellular organismal signaling GO:0035637 44 0.013
organ morphogenesis GO:0009887 75 0.013
learning or memory GO:0007611 90 0.013
nucleoside metabolic process GO:0009116 179 0.013
luteolysis GO:0001554 5 0.013
response to mechanical stimulus GO:0009612 134 0.013
protein autophosphorylation GO:0046777 66 0.013
response to growth factor GO:0070848 189 0.013
regulation of gluconeogenesis GO:0006111 4 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
positive regulation of transferase activity GO:0051347 81 0.013
defense response GO:0006952 194 0.013
interleukin 12 production GO:0032615 3 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
nucleosome organization GO:0034728 1 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
protein localization to nucleus GO:0034504 39 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
Human Rat
cellular protein complex assembly GO:0043623 44 0.013
Human Rat
neuronal action potential GO:0019228 35 0.013
cell cycle checkpoint GO:0000075 2 0.013
cation transmembrane transport GO:0098655 263 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
Rat
regulation of neuron differentiation GO:0045664 208 0.013
Rat
regulation of intracellular protein transport GO:0033157 34 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.013
regulation of membrane potential GO:0042391 110 0.012
developmental growth GO:0048589 100 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
hormone secretion GO:0046879 115 0.012
bmp signaling pathway GO:0030509 4 0.012
Human Rat
intracellular receptor signaling pathway GO:0030522 35 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
liver development GO:0001889 90 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 28 0.012
regulation of embryonic development GO:0045995 2 0.012
positive regulation of secretion GO:0051047 140 0.012
heart process GO:0003015 57 0.012
response to retinoic acid GO:0032526 63 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
cytokine mediated signaling pathway GO:0019221 43 0.012
calcium ion homeostasis GO:0055074 162 0.012
cytokine production GO:0001816 61 0.012
Rat
regulation of intracellular transport GO:0032386 65 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
response to metal ion GO:0010038 253 0.012
innate immune response GO:0045087 35 0.012
cell morphogenesis GO:0000902 142 0.012
Rat
negative regulation of intracellular signal transduction GO:1902532 38 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
glycerolipid metabolic process GO:0046486 67 0.012
aromatic compound catabolic process GO:0019439 168 0.012
response to molecule of bacterial origin GO:0002237 194 0.011
nucleotide catabolic process GO:0009166 139 0.011
regulation of muscle system process GO:0090257 79 0.011
regulation of microtubule cytoskeleton organization GO:0070507 14 0.011
cellular homeostasis GO:0019725 252 0.011
cell adhesion GO:0007155 110 0.011
Rat
alcohol metabolic process GO:0006066 77 0.011
sex differentiation GO:0007548 113 0.011
Rat
heterocycle catabolic process GO:0046700 167 0.011
negative regulation of secretion GO:0051048 82 0.011
localization of cell GO:0051674 202 0.011
Rat
neuron fate commitment GO:0048663 4 0.011
action potential GO:0001508 54 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
Rat
membrane organization GO:0061024 94 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
regulation of anatomical structure size GO:0090066 135 0.011
molting cycle process GO:0022404 2 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
Human
positive regulation of protein transport GO:0051222 41 0.011
cardiovascular system development GO:0072358 134 0.011
interleukin 1 beta secretion GO:0050702 3 0.011
neuronal stem cell division GO:0036445 1 0.011
regulation of cysteine type endopeptidase activity GO:2000116 32 0.011
Rat
molting cycle GO:0042303 3 0.011
negative regulation of cell development GO:0010721 82 0.011
positive regulation of organelle organization GO:0010638 48 0.011
Rat
regulation of blood circulation GO:1903522 110 0.011
signal release GO:0023061 145 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.010
regulation of peptidase activity GO:0052547 55 0.010
Rat
positive regulation of secretion by cell GO:1903532 128 0.010
adult locomotory behavior GO:0008344 4 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
response to lipopolysaccharide GO:0032496 191 0.010
behavior GO:0007610 205 0.010
Rat
pigment biosynthetic process GO:0046148 4 0.010
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.010
Rat

Smad2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.022
cancer DOID:162 0 0.022
organ system cancer DOID:0050686 0 0.022
nervous system disease DOID:863 0 0.017
disease of anatomical entity DOID:7 0 0.017
central nervous system disease DOID:331 0 0.012