Rattus norvegicus

0 known processes

Smap2

small ArfGAP2

(Aliases: RGD1308418,Smap1l)

Smap2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 181 0.504
protein phosphorylation GO:0006468 345 0.189
cellular component assembly GO:0022607 360 0.175
regulation of molecular function GO:0065009 398 0.140
endocytosis GO:0006897 84 0.120
regulation of phosphorus metabolic process GO:0051174 349 0.105
regulation of catalytic activity GO:0050790 304 0.102
organelle organization GO:0006996 266 0.099
positive regulation of phosphorus metabolic process GO:0010562 262 0.096
oxoacid metabolic process GO:0043436 290 0.086
regulation of protein phosphorylation GO:0001932 183 0.085
regulation of signal transduction GO:0009966 318 0.077
cation transport GO:0006812 382 0.075
cellular component biogenesis GO:0044085 368 0.071
organic acid metabolic process GO:0006082 292 0.070
protein complex biogenesis GO:0070271 263 0.066
single organism behavior GO:0044708 130 0.063
synaptic growth at neuromuscular junction GO:0051124 1 0.062
actin filament based process GO:0030029 86 0.062
olfactory learning GO:0008355 1 0.062
nucleoside phosphate metabolic process GO:0006753 283 0.062
macromolecular complex subunit organization GO:0043933 339 0.061
intracellular signal transduction GO:0035556 314 0.059
positive regulation of phosphate metabolic process GO:0045937 262 0.057
positive regulation of transport GO:0051050 245 0.056
regulation of intracellular signal transduction GO:1902531 218 0.054
programmed cell death GO:0012501 392 0.054
positive regulation of protein phosphorylation GO:0001934 135 0.053
secretion by cell GO:0032940 248 0.053
negative regulation of signaling GO:0023057 157 0.052
apoptotic process GO:0006915 381 0.052
metal ion transport GO:0030001 289 0.052
secretion GO:0046903 307 0.050
actin cytoskeleton organization GO:0030036 73 0.050
regulation of cellular component organization GO:0051128 368 0.049
positive regulation of cell death GO:0010942 184 0.048
regulation of secretion by cell GO:1903530 208 0.048
regulation of phosphorylation GO:0042325 248 0.048
protein autophosphorylation GO:0046777 66 0.047
regulation of cellular amino acid metabolic process GO:0006521 2 0.047
peptidyl amino acid modification GO:0018193 126 0.047
regulation of cellular localization GO:0060341 263 0.046
negative regulation of response to stimulus GO:0048585 155 0.045
protein complex assembly GO:0006461 263 0.045
neuron differentiation GO:0030182 368 0.045
macromolecular complex assembly GO:0065003 273 0.045
organic substance catabolic process GO:1901575 316 0.045
small gtpase mediated signal transduction GO:0007264 36 0.044
cellular lipid metabolic process GO:0044255 208 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.044
single organism organelle organization GO:1902589 180 0.043
positive regulation of cellular component organization GO:0051130 200 0.042
chemosensory behavior GO:0007635 2 0.042
cellular amine metabolic process GO:0044106 38 0.042
ras protein signal transduction GO:0007265 29 0.042
regulation of protein kinase activity GO:0045859 105 0.041
positive regulation of cell communication GO:0010647 271 0.041
positive regulation of protein modification process GO:0031401 142 0.041
positive regulation of molecular function GO:0044093 230 0.040
cellular amino acid metabolic process GO:0006520 107 0.040
positive regulation of secretion GO:0051047 140 0.040
neuron projection development GO:0031175 273 0.040
reproductive process GO:0022414 372 0.040
developmental process involved in reproduction GO:0003006 159 0.040
intracellular transport GO:0046907 185 0.039
ion transmembrane transport GO:0034220 365 0.039
regulation of secretion GO:0051046 224 0.038
regulation of cell differentiation GO:0045595 320 0.038
gonad development GO:0008406 104 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.037
regulation of ion transport GO:0043269 245 0.037
locomotion GO:0040011 237 0.037
carboxylic acid metabolic process GO:0019752 289 0.037
cell projection organization GO:0030030 302 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
anion transport GO:0006820 178 0.035
regulation of cellular amine metabolic process GO:0033238 8 0.035
protein complex subunit organization GO:0071822 302 0.035
regulation of organelle organization GO:0033043 80 0.035
cellular protein localization GO:0034613 122 0.035
single organism reproductive process GO:0044702 297 0.035
cellular ketone metabolic process GO:0042180 51 0.034
aging GO:0007568 241 0.034
neuron development GO:0048666 286 0.034
protein localization GO:0008104 191 0.034
negative regulation of transport GO:0051051 136 0.034
regulation of multicellular organismal development GO:2000026 376 0.033
positive regulation of cellular amine metabolic process GO:0033240 3 0.033
negative regulation of cell death GO:0060548 229 0.033
development of primary sexual characteristics GO:0045137 107 0.033
negative regulation of cell communication GO:0010648 158 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
positive regulation of catalytic activity GO:0043085 184 0.032
negative regulation of molecular function GO:0044092 133 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
regulation of map kinase activity GO:0043405 53 0.031
negative regulation of metabolic process GO:0009892 331 0.031
regulation of protein modification process GO:0031399 194 0.031
positive regulation of cell proliferation GO:0008284 249 0.031
peptidyl tyrosine modification GO:0018212 72 0.031
positive regulation of secretion by cell GO:1903532 128 0.031
behavior GO:0007610 205 0.031
transmembrane transport GO:0055085 412 0.031
cellular macromolecule localization GO:0070727 122 0.030
signal transduction by phosphorylation GO:0023014 144 0.030
cellular component morphogenesis GO:0032989 155 0.030
regulation of protein complex assembly GO:0043254 33 0.030
positive regulation of rna metabolic process GO:0051254 203 0.030
response to radiation GO:0009314 137 0.029
olfactory behavior GO:0042048 2 0.029
positive regulation of developmental process GO:0051094 283 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
cellular response to stress GO:0033554 269 0.029
amine metabolic process GO:0009308 38 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
nitrogen compound transport GO:0071705 229 0.028
negative regulation of apoptotic process GO:0043066 181 0.028
protein localization to membrane GO:0072657 36 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.027
reproductive structure development GO:0048608 128 0.027
actin filament organization GO:0007015 42 0.027
signal release GO:0023061 145 0.027
regulation of nervous system development GO:0051960 264 0.027
establishment of organelle localization GO:0051656 37 0.027
establishment of protein localization GO:0045184 141 0.027
single organism catabolic process GO:0044712 283 0.026
organophosphate metabolic process GO:0019637 370 0.026
positive regulation of programmed cell death GO:0043068 157 0.026
regulation of apoptotic process GO:0042981 335 0.026
regulation of neuron death GO:1901214 115 0.026
regulation of actin cytoskeleton organization GO:0032956 30 0.026
regulation of rna metabolic process GO:0051252 391 0.026
membrane organization GO:0061024 94 0.026
insulin like growth factor receptor signaling pathway GO:0048009 3 0.026
head development GO:0060322 247 0.025
regulation of neuron apoptotic process GO:0043523 83 0.025
receptor mediated endocytosis GO:0006898 42 0.025
regulation of transferase activity GO:0051338 123 0.025
regulation of cell development GO:0060284 263 0.025
regulation of cell proliferation GO:0042127 359 0.024
sex differentiation GO:0007548 113 0.024
cellular macromolecular complex assembly GO:0034622 58 0.024
regulation of ion transmembrane transport GO:0034765 121 0.024
regulation of vesicle mediated transport GO:0060627 81 0.024
response to peptide hormone GO:0043434 278 0.024
cytoskeleton organization GO:0007010 111 0.024
regulation of transmembrane transport GO:0034762 122 0.024
positive regulation of protein kinase activity GO:0045860 73 0.024
positive regulation of neuron differentiation GO:0045666 126 0.024
exocytosis GO:0006887 60 0.024
negative regulation of protein phosphorylation GO:0001933 44 0.023
mapk cascade GO:0000165 140 0.023
reproduction GO:0000003 245 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.023
regulation of anatomical structure size GO:0090066 135 0.023
negative regulation of neuron apoptotic process GO:0043524 45 0.023
cell type specific apoptotic process GO:0097285 134 0.023
single organism cellular localization GO:1902580 102 0.023
regulation of programmed cell death GO:0043067 341 0.023
peptidyl tyrosine phosphorylation GO:0018108 72 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
negative regulation of phosphorus metabolic process GO:0010563 80 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
growth GO:0040007 165 0.022
regulation of neurogenesis GO:0050767 247 0.022
regulation of metal ion transport GO:0010959 118 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
nucleotide metabolic process GO:0009117 279 0.022
regulation of cytoskeleton organization GO:0051493 49 0.022
cellular protein complex assembly GO:0043623 44 0.022
female gonad development GO:0008585 53 0.022
positive regulation of cell migration GO:0030335 96 0.021
peptidyl serine modification GO:0018209 34 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
memory GO:0007613 54 0.021
cell morphogenesis GO:0000902 142 0.021
establishment of vesicle localization GO:0051650 31 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
receptor internalization GO:0031623 14 0.020
regulation of neuron projection development GO:0010975 161 0.020
reproductive system development GO:0061458 128 0.020
cytoplasmic transport GO:0016482 115 0.020
protein oligomerization GO:0051259 191 0.020
response to toxic substance GO:0009636 133 0.020
asymmetric protein localization GO:0008105 2 0.020
regulation of cellular component biogenesis GO:0044087 86 0.020
defense response GO:0006952 194 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
regulation of protein metabolic process GO:0051246 289 0.019
organelle localization GO:0051640 55 0.019
positive regulation of nervous system development GO:0051962 178 0.019
response to other organism GO:0051707 220 0.019
positive regulation of catabolic process GO:0009896 78 0.019
immune system process GO:0002376 204 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
peptidyl serine phosphorylation GO:0018105 33 0.018
immune response GO:0006955 104 0.018
divalent inorganic cation transport GO:0072511 134 0.018
regulation of kinase activity GO:0043549 117 0.018
purine containing compound metabolic process GO:0072521 253 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
regulation of hormone levels GO:0010817 187 0.018
anterior posterior pattern specification GO:0009952 1 0.018
response to wounding GO:0009611 254 0.018
brain development GO:0007420 247 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
maintenance of location GO:0051235 17 0.017
ovulation cycle process GO:0022602 50 0.017
positive regulation of gene expression GO:0010628 244 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
negative regulation of phosphate metabolic process GO:0045936 80 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
response to mechanical stimulus GO:0009612 134 0.017
negative regulation of signal transduction GO:0009968 83 0.017
response to ketone GO:1901654 182 0.017
positive regulation of lipid kinase activity GO:0090218 2 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
cell projection morphogenesis GO:0048858 123 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
neuron death GO:0070997 127 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.016
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.016
single organism intracellular transport GO:1902582 166 0.016
response to decreased oxygen levels GO:0036293 237 0.016
rna biosynthetic process GO:0032774 380 0.016
formation of primary germ layer GO:0001704 1 0.016
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.016
positive regulation of signaling GO:0023056 270 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
negative regulation of gene expression GO:0010629 199 0.016
cell adhesion GO:0007155 110 0.016
axis specification GO:0009798 4 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
positive regulation of immune system process GO:0002684 90 0.016
axonogenesis GO:0007409 71 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
cellular response to insulin stimulus GO:0032869 81 0.016
response to hydrogen peroxide GO:0042542 89 0.016
learning or memory GO:0007611 90 0.015
regulation of hydrolase activity GO:0051336 143 0.015
neuron projection morphogenesis GO:0048812 122 0.015
cellular chemical homeostasis GO:0055082 247 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
activation of protein kinase b activity GO:0032148 3 0.015
cytoskeleton dependent cytokinesis GO:0061640 2 0.015
calcium ion transport GO:0006816 131 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
regulation of ion transmembrane transporter activity GO:0032412 48 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
response to inorganic substance GO:0010035 377 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
negative regulation of protein kinase activity GO:0006469 23 0.015
regulation of actin filament based process GO:0032970 42 0.015
regulation of protein serine threonine kinase activity GO:0071900 64 0.015
adult locomotory behavior GO:0008344 4 0.015
sequestering of metal ion GO:0051238 9 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
neurological system process GO:0050877 219 0.015
negative regulation of innate immune response GO:0045824 4 0.015
sodium ion transport GO:0006814 82 0.015
cation transmembrane transport GO:0098655 263 0.015
muscle system process GO:0003012 115 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
regulation of transporter activity GO:0032409 50 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
response to extracellular stimulus GO:0009991 380 0.014
cell migration GO:0016477 197 0.014
ovulation cycle GO:0042698 67 0.014
regulation of growth GO:0040008 105 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
regulation of muscle system process GO:0090257 79 0.014
positive regulation of cell development GO:0010720 176 0.014
erk1 and erk2 cascade GO:0070371 48 0.014
homeostatic process GO:0042592 331 0.014
negative regulation of ion transmembrane transporter activity GO:0032413 12 0.014
sequestering of calcium ion GO:0051208 8 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
multicellular organism reproduction GO:0032504 233 0.014
axon development GO:0061564 96 0.014
regulation of locomotion GO:0040012 148 0.014
cellular cation homeostasis GO:0030003 180 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
regulation of anion transport GO:0044070 43 0.014
chemical homeostasis GO:0048878 292 0.014
response to cytokine GO:0034097 215 0.014
gastrulation GO:0007369 2 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
aromatic compound catabolic process GO:0019439 168 0.014
response to oxidative stress GO:0006979 186 0.014
immune effector process GO:0002252 53 0.013
lipid metabolic process GO:0006629 283 0.013
response to oxygen levels GO:0070482 265 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
negative regulation of cell cycle phase transition GO:1901988 4 0.013
cellular component movement GO:0006928 248 0.013
response to growth factor GO:0070848 189 0.013
response to alkaloid GO:0043279 132 0.013
response to ethanol GO:0045471 162 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
oxidation reduction process GO:0055114 304 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
response to heat GO:0009408 60 0.013
wound healing GO:0042060 122 0.013
protein transport GO:0015031 132 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
regulation of transmembrane transporter activity GO:0022898 49 0.013
cellular catabolic process GO:0044248 295 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of neuron differentiation GO:0045664 208 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
female sex differentiation GO:0046660 59 0.013
carbohydrate metabolic process GO:0005975 130 0.013
response to corticosteroid GO:0031960 235 0.013
positive regulation of phosphorylation GO:0042327 177 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
purine containing compound catabolic process GO:0072523 138 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
organic anion transport GO:0015711 132 0.012
regulation of erk1 and erk2 cascade GO:0070372 41 0.012
catabolic process GO:0009056 351 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
regulation of immune system process GO:0002682 123 0.012
histamine secretion involved in inflammatory response GO:0002441 3 0.012
central nervous system development GO:0007417 311 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
epidermal growth factor receptor signaling pathway GO:0007173 23 0.012
rna metabolic process GO:0016070 406 0.012
regulation of developmental growth GO:0048638 45 0.012
regulation of cell projection organization GO:0031344 175 0.012
nucleic acid templated transcription GO:0097659 379 0.012
response to glucocorticoid GO:0051384 223 0.012
positive regulation of organelle organization GO:0010638 48 0.012
embryonic pattern specification GO:0009880 1 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
response to carbohydrate GO:0009743 183 0.012
cell cell signaling GO:0007267 335 0.012
response to biotic stimulus GO:0009607 226 0.012
regulation of cellular component size GO:0032535 51 0.012
endomembrane system organization GO:0010256 48 0.012
taxis GO:0042330 67 0.012
single organism biosynthetic process GO:0044711 342 0.012
cell activation GO:0001775 97 0.012
actin polymerization or depolymerization GO:0008154 14 0.012
cellular response to oxygen levels GO:0071453 60 0.011
response to reactive oxygen species GO:0000302 120 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
nucleoside metabolic process GO:0009116 179 0.011
response to insulin GO:0032868 133 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
developmental growth GO:0048589 100 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
intracellular protein transport GO:0006886 79 0.011
hormone transport GO:0009914 121 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.011
heterocycle catabolic process GO:0046700 167 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cytokine production GO:0001816 61 0.011
muscle cell proliferation GO:0033002 84 0.011
divalent metal ion transport GO:0070838 132 0.011
amide transport GO:0042886 105 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
synaptic vesicle endocytosis GO:0048488 4 0.011
salivary gland morphogenesis GO:0007435 1 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
regulation of muscle contraction GO:0006937 53 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
organic acid transport GO:0015849 116 0.011
salivary gland development GO:0007431 3 0.011
cellular response to oxidative stress GO:0034599 76 0.011
cellular response to external stimulus GO:0071496 118 0.011
rna localization GO:0006403 4 0.011
localization of cell GO:0051674 202 0.011
muscle contraction GO:0006936 88 0.011
cell part morphogenesis GO:0032990 123 0.011
lipid storage GO:0019915 1 0.011
cell cycle checkpoint GO:0000075 2 0.011
response to amino acid GO:0043200 75 0.011
regulation of stem cell differentiation GO:2000736 2 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
synaptic transmission GO:0007268 235 0.010
regulation of calcium ion transport GO:0051924 77 0.010
regulation of transcription dna templated GO:0006355 374 0.010
vesicle docking involved in exocytosis GO:0006904 4 0.010
erbb signaling pathway GO:0038127 23 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
cellular response to peptide GO:1901653 133 0.010
regulation of body fluid levels GO:0050878 90 0.010
cell motility GO:0048870 202 0.010
response to lipopolysaccharide GO:0032496 191 0.010
negative regulation of intracellular signal transduction GO:1902532 38 0.010
dephosphorylation GO:0016311 98 0.010
cellular homeostasis GO:0019725 252 0.010
regulation of system process GO:0044057 208 0.010
response to axon injury GO:0048678 59 0.010
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.010

Smap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.014
nervous system disease DOID:863 0 0.014
disease of anatomical entity DOID:7 0 0.014