Rattus norvegicus

13 known processes

Smc1a

structural maintenance of chromosomes 1A

(Aliases: KIAA0178,Smc1l1,SMC-1A,SB1.8)

Smc1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin assembly or disassembly GO:0006333 1 0.232
negative regulation of rna biosynthetic process GO:1902679 118 0.156
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.149
transcription from rna polymerase ii promoter GO:0006366 252 0.133
positive regulation of biosynthetic process GO:0009891 319 0.114
response to nutrient levels GO:0031667 370 0.110
regulation of protein metabolic process GO:0051246 289 0.107
rna metabolic process GO:0016070 406 0.101
oxoacid metabolic process GO:0043436 290 0.091
regulation of molecular function GO:0065009 398 0.090
rna biosynthetic process GO:0032774 380 0.086
negative regulation of cellular metabolic process GO:0031324 281 0.082
protein complex biogenesis GO:0070271 263 0.081
carboxylic acid metabolic process GO:0019752 289 0.075
negative regulation of metabolic process GO:0009892 331 0.070
positive regulation of cell death GO:0010942 184 0.068
negative regulation of rna metabolic process GO:0051253 123 0.068
regulation of programmed cell death GO:0043067 341 0.066
positive regulation of apoptotic process GO:0043065 154 0.063
positive regulation of rna metabolic process GO:0051254 203 0.061
response to nutrient GO:0007584 248 0.061
lipid metabolic process GO:0006629 283 0.059
organic acid metabolic process GO:0006082 292 0.059
carbohydrate derivative metabolic process GO:1901135 346 0.057
negative regulation of cellular biosynthetic process GO:0031327 161 0.056
cell projection organization GO:0030030 302 0.056
wound healing GO:0042060 122 0.055
macromolecular complex subunit organization GO:0043933 339 0.054
nucleosome organization GO:0034728 1 0.054
regulation of rna metabolic process GO:0051252 391 0.052
dna packaging GO:0006323 4 0.051
response to extracellular stimulus GO:0009991 380 0.050
positive regulation of cellular biosynthetic process GO:0031328 295 0.049
nitrogen compound transport GO:0071705 229 0.048
cellular response to stress GO:0033554 269 0.048
positive regulation of gene expression GO:0010628 244 0.045
alternative mrna splicing via spliceosome GO:0000380 4 0.045
cellular component biogenesis GO:0044085 368 0.045
positive regulation of nucleic acid templated transcription GO:1903508 197 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
protein complex assembly GO:0006461 263 0.044
regulation of cellular component movement GO:0051270 150 0.044
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.044
ion transmembrane transport GO:0034220 365 0.044
nucleic acid templated transcription GO:0097659 379 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.042
monovalent inorganic cation transport GO:0015672 172 0.042
cation transmembrane transport GO:0098655 263 0.041
secretion GO:0046903 307 0.041
cellular amino acid metabolic process GO:0006520 107 0.041
positive regulation of cellular protein metabolic process GO:0032270 167 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.041
cation transport GO:0006812 382 0.040
regulation of canonical wnt signaling pathway GO:0060828 4 0.040
intracellular transport GO:0046907 185 0.040
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.040
macromolecular complex assembly GO:0065003 273 0.040
single organism biosynthetic process GO:0044711 342 0.040
tissue development GO:0009888 252 0.039
macromolecule localization GO:0033036 252 0.039
neuron differentiation GO:0030182 368 0.039
negative regulation of nucleic acid templated transcription GO:1903507 117 0.038
response to growth factor GO:0070848 189 0.038
positive regulation of phosphate metabolic process GO:0045937 262 0.037
response to molecule of bacterial origin GO:0002237 194 0.037
amine metabolic process GO:0009308 38 0.036
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
regulation of cellular protein metabolic process GO:0032268 267 0.035
metal ion transport GO:0030001 289 0.035
transmembrane transport GO:0055085 412 0.035
organophosphate metabolic process GO:0019637 370 0.035
positive regulation of transcription dna templated GO:0045893 197 0.035
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.034
single organism reproductive process GO:0044702 297 0.034
cellular response to endogenous stimulus GO:0071495 377 0.033
negative regulation of biosynthetic process GO:0009890 168 0.033
regulation of rna biosynthetic process GO:2001141 381 0.033
positive regulation of programmed cell death GO:0043068 157 0.033
reproduction GO:0000003 245 0.033
multicellular organism growth GO:0035264 1 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
cellular component assembly GO:0022607 360 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
regulation of mrna splicing via spliceosome GO:0048024 3 0.030
positive regulation of phosphorylation GO:0042327 177 0.030
single organism catabolic process GO:0044712 283 0.029
cellular response to growth factor stimulus GO:0071363 162 0.029
positive regulation of protein metabolic process GO:0051247 178 0.029
regulation of cellular response to stress GO:0080135 49 0.028
response to lipopolysaccharide GO:0032496 191 0.028
regulation of organelle organization GO:0033043 80 0.028
regulation of apoptotic process GO:0042981 335 0.028
negative regulation of gene expression GO:0010629 199 0.027
head development GO:0060322 247 0.027
organelle organization GO:0006996 266 0.027
cellular ketone metabolic process GO:0042180 51 0.027
programmed cell death GO:0012501 392 0.027
apoptotic signaling pathway GO:0097190 27 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
neuromuscular synaptic transmission GO:0007274 2 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
purine containing compound metabolic process GO:0072521 253 0.025
protein oligomerization GO:0051259 191 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
transforming growth factor beta3 production GO:0032907 2 0.025
establishment of protein localization GO:0045184 141 0.025
protein transport GO:0015031 132 0.025
regulation of signal transduction GO:0009966 318 0.024
positive regulation of cell communication GO:0010647 271 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
response to peptide GO:1901652 292 0.024
cofactor metabolic process GO:0051186 95 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
monocarboxylic acid metabolic process GO:0032787 152 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.023
transcription dna templated GO:0006351 377 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
hair cell differentiation GO:0035315 2 0.023
positive regulation of cell development GO:0010720 176 0.023
regulation of cellular localization GO:0060341 263 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
regulation of response to stress GO:0080134 126 0.023
inorganic cation transmembrane transport GO:0098662 202 0.022
potassium ion transport GO:0006813 97 0.022
regeneration GO:0031099 163 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.022
organophosphate biosynthetic process GO:0090407 143 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
cellular amine metabolic process GO:0044106 38 0.021
cellular homeostasis GO:0019725 252 0.021
positive regulation of protein modification process GO:0031401 142 0.021
sodium ion transport GO:0006814 82 0.021
cellular lipid metabolic process GO:0044255 208 0.021
regulation of neurogenesis GO:0050767 247 0.021
regulation of cell differentiation GO:0045595 320 0.021
Mouse
regulation of phosphorylation GO:0042325 248 0.021
chemical homeostasis GO:0048878 292 0.021
regulation of neuron projection development GO:0010975 161 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
apoptotic process GO:0006915 381 0.020
regulation of cellular component biogenesis GO:0044087 86 0.020
single organism carbohydrate metabolic process GO:0044723 118 0.020
regulation of cell proliferation GO:0042127 359 0.020
positive regulation of signal transduction GO:0009967 175 0.020
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
multi organism reproductive process GO:0044703 262 0.020
nucleotide metabolic process GO:0009117 279 0.019
positive regulation of transport GO:0051050 245 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
response to hypoxia GO:0001666 231 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
single organism intracellular transport GO:1902582 166 0.019
response to oxygen levels GO:0070482 265 0.019
protein complex subunit organization GO:0071822 302 0.019
brain development GO:0007420 247 0.019
vasculature development GO:0001944 70 0.019
regulation of cellular component organization GO:0051128 368 0.019
organophosphate catabolic process GO:0046434 148 0.019
response to starvation GO:0042594 59 0.019
regulation of transforming growth factor beta3 production GO:0032910 2 0.019
regulation of hormone levels GO:0010817 187 0.019
blood circulation GO:0008015 183 0.019
response to wounding GO:0009611 254 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
intracellular signal transduction GO:0035556 314 0.019
positive regulation of molecular function GO:0044093 230 0.019
peptidyl amino acid modification GO:0018193 126 0.019
response to ethanol GO:0045471 162 0.018
ribonucleoside catabolic process GO:0042454 126 0.018
activation of cysteine type endopeptidase activity GO:0097202 4 0.018
response to bacterium GO:0009617 200 0.018
positive regulation of cytokine production GO:0001819 42 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
mrna stabilization GO:0048255 2 0.018
negative regulation of rna splicing GO:0033119 3 0.018
positive regulation of signaling GO:0023056 270 0.018
regulation of bmp signaling pathway GO:0030510 2 0.018
response to toxic substance GO:0009636 133 0.018
monocarboxylic acid transport GO:0015718 52 0.017
proteolysis GO:0006508 175 0.017
regulation of transcription dna templated GO:0006355 374 0.017
establishment of protein localization to organelle GO:0072594 44 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
response to transforming growth factor beta GO:0071559 46 0.017
small molecule catabolic process GO:0044282 59 0.017
carbohydrate metabolic process GO:0005975 130 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
cellular response to abiotic stimulus GO:0071214 85 0.017
hormone secretion GO:0046879 115 0.017
regulation of growth GO:0040008 105 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
response to decreased oxygen levels GO:0036293 237 0.016
cellular component movement GO:0006928 248 0.016
female pregnancy GO:0007565 122 0.016
oxidation reduction process GO:0055114 304 0.016
regulation of chromosome organization GO:0033044 9 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
secretion by cell GO:0032940 248 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
signal release GO:0023061 145 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
locomotion GO:0040011 237 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
lipid biosynthetic process GO:0008610 128 0.015
central nervous system development GO:0007417 311 0.015
epithelial cell differentiation GO:0030855 71 0.015
epithelium development GO:0060429 96 0.015
gliogenesis GO:0042063 93 0.015
regulation of cell projection organization GO:0031344 175 0.015
protein phosphorylation GO:0006468 345 0.015
regulation of response to external stimulus GO:0032101 106 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
anion transport GO:0006820 178 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
sexual reproduction GO:0019953 148 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
response to tumor necrosis factor GO:0034612 56 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
immune system process GO:0002376 204 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
mrna metabolic process GO:0016071 20 0.014
inflammatory response GO:0006954 150 0.014
cell motility GO:0048870 202 0.014
protein processing GO:0016485 68 0.014
regulation of catalytic activity GO:0050790 304 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
small molecule biosynthetic process GO:0044283 124 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
negative regulation of secretion GO:0051048 82 0.014
camera type eye development GO:0043010 48 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
cellular component morphogenesis GO:0032989 155 0.013
regulation of mrna stability GO:0043488 3 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
response to vitamin GO:0033273 131 0.013
response to other organism GO:0051707 220 0.013
regulation of ion transport GO:0043269 245 0.013
circulatory system process GO:0003013 183 0.013
calcium ion homeostasis GO:0055074 162 0.013
cell type specific apoptotic process GO:0097285 134 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
bmp signaling pathway GO:0030509 4 0.013
rna localization GO:0006403 4 0.013
positive regulation of jnk cascade GO:0046330 13 0.013
regulation of metal ion transport GO:0010959 118 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
cytoplasmic transport GO:0016482 115 0.013
cellular chemical homeostasis GO:0055082 247 0.013
negative regulation of cell communication GO:0010648 158 0.013
regulation of cell migration GO:0030334 128 0.013
peptide secretion GO:0002790 86 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
positive regulation of cell projection organization GO:0031346 111 0.012
anterior posterior pattern specification GO:0009952 1 0.012
response to oxidative stress GO:0006979 186 0.012
multi multicellular organism process GO:0044706 138 0.012
protein autophosphorylation GO:0046777 66 0.012
neuron projection development GO:0031175 273 0.012
cation homeostasis GO:0055080 195 0.012
lipid transport GO:0006869 61 0.012
cardiovascular system development GO:0072358 134 0.012
nuclear transport GO:0051169 49 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
ossification GO:0001503 70 0.012
response to biotic stimulus GO:0009607 226 0.012
single organism organelle organization GO:1902589 180 0.012
response to purine containing compound GO:0014074 126 0.012
localization of cell GO:0051674 202 0.012
positive regulation of immune system process GO:0002684 90 0.012
positive regulation of ion transport GO:0043270 94 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.011
neuron development GO:0048666 286 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
coenzyme metabolic process GO:0006732 86 0.011
cellular response to lipid GO:0071396 201 0.011
regulation of nervous system development GO:0051960 264 0.011
cellular response to tumor necrosis factor GO:0071356 46 0.011
positive regulation of developmental process GO:0051094 283 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
chromatin modification GO:0016568 33 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
response to external biotic stimulus GO:0043207 221 0.011
axis specification GO:0009798 4 0.011
regulation of histone modification GO:0031056 8 0.011
response to metal ion GO:0010038 253 0.011
growth GO:0040007 165 0.011
immune response GO:0006955 104 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
single organism cellular localization GO:1902580 102 0.011
rna stabilization GO:0043489 2 0.011
positive regulation of cytoplasmic transport GO:1903651 32 0.011
regulation of anatomical structure size GO:0090066 135 0.011
metal ion homeostasis GO:0055065 186 0.011
regulation of secretion GO:0051046 224 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
alcohol metabolic process GO:0006066 77 0.010
nucleoside metabolic process GO:0009116 179 0.010
catabolic process GO:0009056 351 0.010
nucleic acid transport GO:0050657 3 0.010
regulation of system process GO:0044057 208 0.010
cell cycle checkpoint GO:0000075 2 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.010
regulation of locomotion GO:0040012 148 0.010
necroptotic process GO:0070266 2 0.010
protein targeting GO:0006605 61 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.010
heart contraction GO:0060047 57 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
negative regulation of signal transduction GO:0009968 83 0.010
circulatory system development GO:0072359 134 0.010

Smc1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.013