Rattus norvegicus

0 known processes

Sorbs3

sorbin and SH3 domain containing 3

(Aliases: MGC94509,Sh3d4)

Sorbs3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 379 0.308
regulation of nucleic acid templated transcription GO:1903506 380 0.298
positive regulation of gene expression GO:0010628 244 0.270
positive regulation of transcription dna templated GO:0045893 197 0.245
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.231
regulation of cell proliferation GO:0042127 359 0.199
negative regulation of cell differentiation GO:0045596 99 0.196
positive regulation of rna metabolic process GO:0051254 203 0.196
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.192
regulation of rna biosynthetic process GO:2001141 381 0.189
positive regulation of cell proliferation GO:0008284 249 0.184
rna metabolic process GO:0016070 406 0.170
positive regulation of nucleic acid templated transcription GO:1903508 197 0.164
regulation of transcription dna templated GO:0006355 374 0.152
positive regulation of rna biosynthetic process GO:1902680 197 0.147
negative regulation of transcription dna templated GO:0045892 116 0.145
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.120
negative regulation of metabolic process GO:0009892 331 0.120
positive regulation of biosynthetic process GO:0009891 319 0.119
regulation of rna metabolic process GO:0051252 391 0.114
negative regulation of macromolecule metabolic process GO:0010605 260 0.107
transmission of nerve impulse GO:0019226 42 0.101
positive regulation of cellular biosynthetic process GO:0031328 295 0.099
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.096
response to wounding GO:0009611 254 0.091
programmed cell death GO:0012501 392 0.086
transcription from rna polymerase ii promoter GO:0006366 252 0.085
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.084
intracellular signal transduction GO:0035556 314 0.077
transcription dna templated GO:0006351 377 0.077
neurological system process GO:0050877 219 0.074
regulation of neurogenesis GO:0050767 247 0.074
regulation of intracellular signal transduction GO:1902531 218 0.071
negative regulation of cellular metabolic process GO:0031324 281 0.071
regulation of signal transduction GO:0009966 318 0.070
positive regulation of phosphorus metabolic process GO:0010562 262 0.067
neuron development GO:0048666 286 0.067
rna biosynthetic process GO:0032774 380 0.064
regulation of nervous system development GO:0051960 264 0.061
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.058
negative regulation of nucleic acid templated transcription GO:1903507 117 0.055
cellular response to oxygen containing compound GO:1901701 386 0.054
positive regulation of cell development GO:0010720 176 0.054
negative regulation of rna metabolic process GO:0051253 123 0.051
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.049
apoptotic process GO:0006915 381 0.049
intracellular transport GO:0046907 185 0.049
neuron differentiation GO:0030182 368 0.047
regulation of multicellular organismal development GO:2000026 376 0.047
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.046
regulation of cell differentiation GO:0045595 320 0.045
anterior posterior pattern specification GO:0009952 1 0.044
tissue development GO:0009888 252 0.044
cellular response to lipid GO:0071396 201 0.043
regulation of molecular function GO:0065009 398 0.043
cell projection organization GO:0030030 302 0.042
regulation of neuron differentiation GO:0045664 208 0.041
response to extracellular stimulus GO:0009991 380 0.040
positive regulation of neurogenesis GO:0050769 165 0.040
localization of cell GO:0051674 202 0.039
negative regulation of biosynthetic process GO:0009890 168 0.039
cellular component movement GO:0006928 248 0.039
negative regulation of rna biosynthetic process GO:1902679 118 0.038
head development GO:0060322 247 0.038
regulation of programmed cell death GO:0043067 341 0.038
response to biotic stimulus GO:0009607 226 0.037
cell motility GO:0048870 202 0.037
kidney development GO:0001822 67 0.035
retinoic acid receptor signaling pathway GO:0048384 7 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.035
negative regulation of cell death GO:0060548 229 0.034
positive regulation of signaling GO:0023056 270 0.033
reproduction GO:0000003 245 0.033
organelle organization GO:0006996 266 0.033
Human
response to cytokine GO:0034097 215 0.033
negative regulation of cellular biosynthetic process GO:0031327 161 0.032
regulation of cell development GO:0060284 263 0.032
urogenital system development GO:0001655 78 0.032
positive regulation of developmental process GO:0051094 283 0.032
negative regulation of cell development GO:0010721 82 0.031
positive regulation of intracellular signal transduction GO:1902533 138 0.031
negative regulation of gene expression GO:0010629 199 0.031
protein complex assembly GO:0006461 263 0.031
cell cell signaling GO:0007267 335 0.030
immune system process GO:0002376 204 0.030
negative regulation of developmental process GO:0051093 125 0.030
anatomical structure morphogenesis GO:0009653 298 0.029
tube development GO:0035295 89 0.028
negative regulation of molecular function GO:0044092 133 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
response to bacterium GO:0009617 200 0.027
defense response GO:0006952 194 0.026
taxis GO:0042330 67 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
protein tetramerization GO:0051262 38 0.025
multicellular organismal signaling GO:0035637 44 0.025
response to nutrient GO:0007584 248 0.025
cardiac chamber development GO:0003205 1 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.024
regulation of neuron projection development GO:0010975 161 0.024
circulatory system process GO:0003013 183 0.024
regulation of lipid metabolic process GO:0019216 68 0.024
locomotion GO:0040011 237 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.023
response to inorganic substance GO:0010035 377 0.023
growth GO:0040007 165 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
negative regulation of catalytic activity GO:0043086 103 0.023
reproductive process GO:0022414 372 0.022
action potential GO:0001508 54 0.022
cell morphogenesis GO:0000902 142 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
cell adhesion GO:0007155 110 0.022
regulation of membrane potential GO:0042391 110 0.022
response to lipopolysaccharide GO:0032496 191 0.022
regulation of cellular component organization GO:0051128 368 0.022
Human
multi multicellular organism process GO:0044706 138 0.022
regulation of protein phosphorylation GO:0001932 183 0.021
neuron projection development GO:0031175 273 0.021
regulation of protein metabolic process GO:0051246 289 0.020
regulation of immune system process GO:0002682 123 0.020
cellular amine metabolic process GO:0044106 38 0.020
macromolecular complex assembly GO:0065003 273 0.020
cellular response to cytokine stimulus GO:0071345 127 0.020
circulatory system development GO:0072359 134 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 11 0.019
biological adhesion GO:0022610 110 0.019
muscle structure development GO:0061061 87 0.019
renal system development GO:0072001 67 0.019
negative regulation of cellular component organization GO:0051129 83 0.018
response to other organism GO:0051707 220 0.018
multi organism reproductive process GO:0044703 262 0.018
chemical homeostasis GO:0048878 292 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
protein complex subunit organization GO:0071822 302 0.018
Human
central nervous system development GO:0007417 311 0.018
cell migration GO:0016477 197 0.018
single organism intracellular transport GO:1902582 166 0.018
regulation of locomotion GO:0040012 148 0.018
carboxylic acid metabolic process GO:0019752 289 0.017
positive regulation of cell communication GO:0010647 271 0.017
negative regulation of nervous system development GO:0051961 79 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.017
negative regulation of immune system process GO:0002683 39 0.017
embryo development GO:0009790 49 0.017
establishment of tissue polarity GO:0007164 2 0.017
protein oligomerization GO:0051259 191 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
multicellular organismal response to stress GO:0033555 25 0.017
cell cycle GO:0007049 101 0.016
organic acid metabolic process GO:0006082 292 0.016
cellular ketone metabolic process GO:0042180 51 0.016
positive regulation of nervous system development GO:0051962 178 0.016
hepaticobiliary system development GO:0061008 90 0.016
cellular response to acid chemical GO:0071229 75 0.016
regulation of cell projection organization GO:0031344 175 0.016
blood circulation GO:0008015 183 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
regulation of apoptotic process GO:0042981 335 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
positive regulation of cellular component movement GO:0051272 102 0.015
positive regulation of cell death GO:0010942 184 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
organ morphogenesis GO:0009887 75 0.015
secretion GO:0046903 307 0.015
single organism reproductive process GO:0044702 297 0.015
protein phosphorylation GO:0006468 345 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
protein heterooligomerization GO:0051291 89 0.015
sensory perception GO:0007600 101 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
axon ensheathment GO:0008366 40 0.014
response to mechanical stimulus GO:0009612 134 0.014
catabolic process GO:0009056 351 0.014
protein complex biogenesis GO:0070271 263 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
ensheathment of neurons GO:0007272 40 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
circadian rhythm GO:0007623 88 0.014
inner ear morphogenesis GO:0042472 1 0.014
tissue morphogenesis GO:0048729 22 0.014
cation homeostasis GO:0055080 195 0.014
endocytosis GO:0006897 84 0.014
positive regulation of protein modification process GO:0031401 142 0.014
regulation of protein modification process GO:0031399 194 0.014
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 3 0.013
negative regulation of neuron differentiation GO:0045665 62 0.013
cellular chemical homeostasis GO:0055082 247 0.013
response to external biotic stimulus GO:0043207 221 0.013
heart morphogenesis GO:0003007 3 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
regulation of phosphorylation GO:0042325 248 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
calcium ion homeostasis GO:0055074 162 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
regeneration GO:0031099 163 0.012
ossification GO:0001503 70 0.012
regulation of catalytic activity GO:0050790 304 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
cellular component morphogenesis GO:0032989 155 0.012
epithelium development GO:0060429 96 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.012
b cell activation involved in immune response GO:0002312 1 0.012
regulation of response to stress GO:0080134 126 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
regulation of cell migration GO:0030334 128 0.012
sensory perception of bitter taste GO:0050913 4 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
cell type specific apoptotic process GO:0097285 134 0.012
regulation of protein localization GO:0032880 81 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
axis specification GO:0009798 4 0.012
cellular component biogenesis GO:0044085 368 0.012
Human
mitotic cell cycle GO:0000278 49 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
jak stat cascade GO:0007259 26 0.012
cardiovascular system development GO:0072358 134 0.011
developmental process involved in reproduction GO:0003006 159 0.011
lipid metabolic process GO:0006629 283 0.011
cell growth GO:0016049 104 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of cell motility GO:2000145 131 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
amine metabolic process GO:0009308 38 0.011
negative regulation of cell communication GO:0010648 158 0.011
negative regulation of intracellular signal transduction GO:1902532 38 0.011
membrane organization GO:0061024 94 0.011
homeostatic process GO:0042592 331 0.011
erythrocyte homeostasis GO:0034101 2 0.011
single organism cellular localization GO:1902580 102 0.011
mesenchymal to epithelial transition GO:0060231 3 0.011
ras protein signal transduction GO:0007265 29 0.011
cell part morphogenesis GO:0032990 123 0.011
regulation of cell cycle process GO:0010564 31 0.010
cellular cation homeostasis GO:0030003 180 0.010
eye morphogenesis GO:0048592 4 0.010
protein processing GO:0016485 68 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
regulation of cell cycle GO:0051726 73 0.010
steroid metabolic process GO:0008202 73 0.010

Sorbs3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.041
disease of anatomical entity DOID:7 0 0.041
sensory system disease DOID:0050155 0 0.020