Rattus norvegicus

0 known processes

Sorcs2

sortilin-related VPS10 domain containing receptor 2

Sorcs2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cognition GO:0050890 92 0.126
response to corticosteroid GO:0031960 235 0.107
organic acid metabolic process GO:0006082 292 0.099
catabolic process GO:0009056 351 0.094
regulation of signal transduction GO:0009966 318 0.068
macromolecule localization GO:0033036 252 0.061
Yeast
cell morphogenesis GO:0000902 142 0.058
organic substance catabolic process GO:1901575 316 0.056
negative regulation of macromolecule metabolic process GO:0010605 260 0.054
behavior GO:0007610 205 0.053
aging GO:0007568 241 0.052
positive regulation of multicellular organismal process GO:0051240 387 0.052
nucleobase containing small molecule metabolic process GO:0055086 316 0.052
purine ribonucleotide metabolic process GO:0009150 227 0.051
oxidation reduction process GO:0055114 304 0.051
positive regulation of signaling GO:0023056 270 0.051
apoptotic process GO:0006915 381 0.050
response to glucocorticoid GO:0051384 223 0.049
nucleotide catabolic process GO:0009166 139 0.048
cellular component movement GO:0006928 248 0.047
organophosphate catabolic process GO:0046434 148 0.047
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.046
transmembrane transport GO:0055085 412 0.046
ribonucleoside triphosphate catabolic process GO:0009203 122 0.046
nucleoside phosphate catabolic process GO:1901292 140 0.045
neuron projection development GO:0031175 273 0.045
cellular catabolic process GO:0044248 295 0.044
regulation of establishment of planar polarity GO:0090175 2 0.043
axon development GO:0061564 96 0.043
organonitrogen compound catabolic process GO:1901565 179 0.043
negative regulation of metabolic process GO:0009892 331 0.043
negative regulation of cellular metabolic process GO:0031324 281 0.042
central nervous system development GO:0007417 311 0.041
regulation of protein modification process GO:0031399 194 0.040
aromatic compound catabolic process GO:0019439 168 0.039
programmed cell death GO:0012501 392 0.039
ribose phosphate metabolic process GO:0019693 235 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.038
purine ribonucleotide catabolic process GO:0009154 136 0.038
purine containing compound metabolic process GO:0072521 253 0.038
purine nucleotide catabolic process GO:0006195 136 0.038
small gtpase mediated signal transduction GO:0007264 36 0.038
regulation of molecular function GO:0065009 398 0.038
sensory perception of pain GO:0019233 73 0.038
purine nucleoside triphosphate catabolic process GO:0009146 122 0.037
brain development GO:0007420 247 0.037
regulation of cell projection organization GO:0031344 175 0.037
response to acid chemical GO:0001101 222 0.036
regulation of cell proliferation GO:0042127 359 0.036
ribonucleoside triphosphate metabolic process GO:0009199 141 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.036
regulation of phosphate metabolic process GO:0019220 349 0.035
single organism catabolic process GO:0044712 283 0.035
regulation of phosphorylation GO:0042325 248 0.035
response to oxygen levels GO:0070482 265 0.035
cellular response to lipid GO:0071396 201 0.035
regulation of catabolic process GO:0009894 113 0.035
purine ribonucleoside metabolic process GO:0046128 168 0.035
nucleoside metabolic process GO:0009116 179 0.034
nucleic acid templated transcription GO:0097659 379 0.034
regulation of nervous system development GO:0051960 264 0.034
regulation of intracellular signal transduction GO:1902531 218 0.034
purine ribonucleoside catabolic process GO:0046130 124 0.033
single organism reproductive process GO:0044702 297 0.033
regulation of nucleotide catabolic process GO:0030811 65 0.033
negative regulation of cell communication GO:0010648 158 0.032
response to nutrient levels GO:0031667 370 0.032
nucleoside triphosphate metabolic process GO:0009141 144 0.032
divalent metal ion transport GO:0070838 132 0.032
response to inorganic substance GO:0010035 377 0.032
glycosyl compound catabolic process GO:1901658 126 0.032
reproductive process GO:0022414 372 0.031
carbohydrate derivative catabolic process GO:1901136 147 0.031
neuron projection morphogenesis GO:0048812 122 0.031
positive regulation of cell death GO:0010942 184 0.031
amine metabolic process GO:0009308 38 0.030
cellular component biogenesis GO:0044085 368 0.030
neuron differentiation GO:0030182 368 0.030
intracellular signal transduction GO:0035556 314 0.030
oxoacid metabolic process GO:0043436 290 0.030
regulation of apoptotic process GO:0042981 335 0.029
negative regulation of signaling GO:0023057 157 0.029
purine nucleoside triphosphate metabolic process GO:0009144 141 0.029
cell motility GO:0048870 202 0.029
regulation of ion transmembrane transport GO:0034765 121 0.028
ion transmembrane transport GO:0034220 365 0.028
regulation of neurogenesis GO:0050767 247 0.028
protein phosphorylation GO:0006468 345 0.028
purine nucleotide metabolic process GO:0006163 229 0.028
ribonucleotide catabolic process GO:0009261 136 0.028
response to ketone GO:1901654 182 0.028
anatomical structure morphogenesis GO:0009653 298 0.027
single organism behavior GO:0044708 130 0.027
regulation of axonogenesis GO:0050770 37 0.027
response to mechanical stimulus GO:0009612 134 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
cellular nitrogen compound catabolic process GO:0044270 163 0.027
ras protein signal transduction GO:0007265 29 0.027
regulation of programmed cell death GO:0043067 341 0.027
locomotory exploration behavior GO:0035641 1 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
ribonucleoside metabolic process GO:0009119 174 0.026
positive regulation of neuron differentiation GO:0045666 126 0.026
response to metal ion GO:0010038 253 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
purine nucleoside catabolic process GO:0006152 124 0.026
positive regulation of cell differentiation GO:0045597 217 0.025
regulation of cellular catabolic process GO:0031329 101 0.025
generation of precursor metabolites and energy GO:0006091 62 0.025
organic cyclic compound catabolic process GO:1901361 175 0.025
cell migration GO:0016477 197 0.025
regulation of hydrolase activity GO:0051336 143 0.025
circulatory system process GO:0003013 183 0.025
gland development GO:0048732 155 0.025
growth GO:0040007 165 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.024
ribonucleoside catabolic process GO:0042454 126 0.024
response to decreased oxygen levels GO:0036293 237 0.024
negative regulation of gene expression GO:0010629 199 0.024
nucleoside catabolic process GO:0009164 126 0.024
regulation of anatomical structure size GO:0090066 135 0.023
regulation of secretion GO:0051046 224 0.023
positive regulation of nervous system development GO:0051962 178 0.023
purine containing compound catabolic process GO:0072523 138 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
positive regulation of neuron migration GO:2001224 2 0.023
sodium ion transport GO:0006814 82 0.023
tissue development GO:0009888 252 0.022
cation transport GO:0006812 382 0.022
rna metabolic process GO:0016070 406 0.022
regulation of cell differentiation GO:0045595 320 0.022
establishment of tissue polarity GO:0007164 2 0.022
cellular component assembly GO:0022607 360 0.022
response to hypoxia GO:0001666 231 0.022
n methyl d aspartate receptor clustering GO:0097114 2 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
regulation of protein metabolic process GO:0051246 289 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.022
organophosphate metabolic process GO:0019637 370 0.022
transcription dna templated GO:0006351 377 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
regulation of transmembrane transport GO:0034762 122 0.022
positive regulation of cell projection organization GO:0031346 111 0.022
cardiovascular system development GO:0072358 134 0.022
response to oxidative stress GO:0006979 186 0.022
multicellular organism reproduction GO:0032504 233 0.021
synapse assembly GO:0007416 29 0.021
cell adhesion GO:0007155 110 0.021
head development GO:0060322 247 0.021
cell projection organization GO:0030030 302 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
rna biosynthetic process GO:0032774 380 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
sensory perception GO:0007600 101 0.021
synapse organization GO:0050808 46 0.021
regulation of cell development GO:0060284 263 0.021
positive regulation of ion transport GO:0043270 94 0.021
female pregnancy GO:0007565 122 0.021
positive regulation of developmental process GO:0051094 283 0.020
regulation of system process GO:0044057 208 0.020
regulation of growth GO:0040008 105 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
heterocycle catabolic process GO:0046700 167 0.020
regulation of purine nucleotide metabolic process GO:1900542 115 0.020
regulation of cellular localization GO:0060341 263 0.020
locomotion GO:0040011 237 0.020
cellular homeostasis GO:0019725 252 0.020
regulation of nucleoside metabolic process GO:0009118 66 0.020
regulation of neuron projection development GO:0010975 161 0.020
biological adhesion GO:0022610 110 0.020
regulation of transcription dna templated GO:0006355 374 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
positive regulation of cell migration GO:0030335 96 0.019
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 3 0.019
cellular response to stress GO:0033554 269 0.019
localization of cell GO:0051674 202 0.019
learning or memory GO:0007611 90 0.019
response to reactive oxygen species GO:0000302 120 0.019
regulation of ion transport GO:0043269 245 0.019
response to wounding GO:0009611 254 0.019
negative regulation of phosphate metabolic process GO:0045936 80 0.019
response to extracellular stimulus GO:0009991 380 0.019
nucleotide metabolic process GO:0009117 279 0.019
positive regulation of neuron projection development GO:0010976 99 0.019
establishment of planar polarity GO:0001736 1 0.019
secretion by cell GO:0032940 248 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
axonogenesis GO:0007409 71 0.019
cellular amine metabolic process GO:0044106 38 0.019
neurological system process GO:0050877 219 0.019
regulation of g0 to g1 transition GO:0070316 3 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
gtp catabolic process GO:0006184 71 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
protein complex subunit organization GO:0071822 302 0.018
chemical homeostasis GO:0048878 292 0.018
single organism intracellular transport GO:1902582 166 0.018
Yeast
dephosphorylation GO:0016311 98 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
positive regulation of cell development GO:0010720 176 0.018
mapk cascade GO:0000165 140 0.018
response to carbohydrate GO:0009743 183 0.018
response to monosaccharide GO:0034284 159 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
response to estradiol GO:0032355 164 0.017
reproductive system development GO:0061458 128 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
synaptic transmission GO:0007268 235 0.017
response to growth factor GO:0070848 189 0.017
rhythmic process GO:0048511 156 0.017
organic hydroxy compound transport GO:0015850 77 0.017
neuron development GO:0048666 286 0.017
neuron apoptotic process GO:0051402 88 0.017
guanosine containing compound catabolic process GO:1901069 71 0.017
regulation of cell morphogenesis GO:0022604 77 0.017
divalent inorganic cation transport GO:0072511 134 0.017
regulation of catalytic activity GO:0050790 304 0.017
response to peptide GO:1901652 292 0.017
cell growth GO:0016049 104 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
epithelium development GO:0060429 96 0.017
chemosensory behavior GO:0007635 2 0.017
single organism carbohydrate metabolic process GO:0044723 118 0.016
cellular response to alcohol GO:0097306 87 0.016
response to hydrogen peroxide GO:0042542 89 0.016
sequestering of metal ion GO:0051238 9 0.016
neurotransmitter gated ion channel clustering GO:0072578 3 0.016
blood circulation GO:0008015 183 0.016
developmental process involved in reproduction GO:0003006 159 0.016
regulation of locomotion GO:0040012 148 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
cell projection morphogenesis GO:0048858 123 0.016
protein localization to membrane GO:0072657 36 0.016
positive regulation of cell communication GO:0010647 271 0.016
metestrus GO:0060210 1 0.016
regulation of cell adhesion GO:0030155 52 0.016
forebrain development GO:0030900 98 0.016
carbohydrate homeostasis GO:0033500 75 0.016
regulation of cell growth GO:0001558 85 0.016
proteolysis GO:0006508 175 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
lipid metabolic process GO:0006629 283 0.015
regulation of cellular component movement GO:0051270 150 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
positive regulation of hydrolase activity GO:0051345 86 0.015
regulation of mesenchymal cell proliferation GO:0010464 4 0.015
neuron fate commitment GO:0048663 4 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
morphogenesis of a polarized epithelium GO:0001738 1 0.015
memory GO:0007613 54 0.015
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.015
vasoconstriction GO:0042310 54 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
cell part morphogenesis GO:0032990 123 0.015
salivary gland development GO:0007431 3 0.014
response to peptide hormone GO:0043434 278 0.014
heart process GO:0003015 57 0.014
rho protein signal transduction GO:0007266 11 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
response to alkaloid GO:0043279 132 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
response to hexose GO:0009746 144 0.014
synaptic transmission glutamatergic GO:0035249 33 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
calcium ion transport GO:0006816 131 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
reproductive structure development GO:0048608 128 0.014
cardiac conduction GO:0061337 2 0.014
regulation of mapk cascade GO:0043408 116 0.014
cell cell signaling GO:0007267 335 0.014
regulation of synaptic plasticity GO:0048167 70 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
homeostatic process GO:0042592 331 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
response to fatty acid GO:0070542 65 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
peptide transport GO:0015833 97 0.013
organic acid transport GO:0015849 116 0.013
regulation of dendrite development GO:0050773 59 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
response to glucose GO:0009749 136 0.013
response to other organism GO:0051707 220 0.013
regulation of secretion by cell GO:1903530 208 0.013
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
respiratory system process GO:0003016 3 0.013
negative regulation of growth GO:0045926 37 0.013
negative regulation of signal transduction GO:0009968 83 0.013
positive regulation of protein modification process GO:0031401 142 0.013
heart contraction GO:0060047 57 0.013
respiratory gaseous exchange GO:0007585 4 0.013
regulation of synaptic transmission GO:0050804 141 0.013
glucose homeostasis GO:0042593 75 0.013
regeneration GO:0031099 163 0.013
hepaticobiliary system development GO:0061008 90 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
development of primary sexual characteristics GO:0045137 107 0.013
positive regulation of molecular function GO:0044093 230 0.013
asymmetric stem cell division GO:0098722 2 0.013
gtp metabolic process GO:0046039 72 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
mechanoreceptor differentiation GO:0042490 2 0.013
response to electrical stimulus GO:0051602 56 0.013
eye morphogenesis GO:0048592 4 0.013
defense response GO:0006952 194 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
response to insulin GO:0032868 133 0.012
cellular lipid metabolic process GO:0044255 208 0.012
glial cell differentiation GO:0010001 65 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
peptide hormone secretion GO:0030072 84 0.012
response to biotic stimulus GO:0009607 226 0.012
exploration behavior GO:0035640 1 0.012
regulation of erk1 and erk2 cascade GO:0070372 41 0.012
developmental growth GO:0048589 100 0.012
regulation of postsynaptic membrane potential GO:0060078 25 0.012
regulation of lyase activity GO:0051339 22 0.012
multi organism reproductive process GO:0044703 262 0.012
regulation of epithelial cell proliferation GO:0050678 49 0.012
circulatory system development GO:0072359 134 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
positive regulation of cell motility GO:2000147 97 0.012
small molecule biosynthetic process GO:0044283 124 0.012
nitrogen compound transport GO:0071705 229 0.012
regulation of rna metabolic process GO:0051252 391 0.012
protein localization GO:0008104 191 0.012
Yeast
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
response to ethanol GO:0045471 162 0.012
cell type specific apoptotic process GO:0097285 134 0.012
intracellular transport GO:0046907 185 0.012
Yeast
sexual reproduction GO:0019953 148 0.012
regulation of cellular component organization GO:0051128 368 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.011
secretion GO:0046903 307 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
reproduction GO:0000003 245 0.011
peptide secretion GO:0002790 86 0.011
amide transport GO:0042886 105 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
positive regulation of peptide hormone secretion GO:0090277 50 0.011
somatic stem cell division GO:0048103 2 0.011
regulation of protein localization GO:0032880 81 0.011
actin filament based process GO:0030029 86 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
response to axon injury GO:0048678 59 0.011
macromolecular complex assembly GO:0065003 273 0.011
energy derivation by oxidation of organic compounds GO:0015980 46 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
regulation of gtpase activity GO:0043087 57 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
regulation of epithelial to mesenchymal transition GO:0010717 2 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
regulation of metal ion transport GO:0010959 118 0.011
defecation GO:0030421 1 0.011
multi multicellular organism process GO:0044706 138 0.011
male gamete generation GO:0048232 99 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
regulation of cell motility GO:2000145 131 0.011
liver development GO:0001889 90 0.011
organ regeneration GO:0031100 101 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
metal ion transport GO:0030001 289 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
organelle organization GO:0006996 266 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
cellular glucan metabolic process GO:0006073 23 0.010
positive regulation of catabolic process GO:0009896 78 0.010
regulation of muscle system process GO:0090257 79 0.010
cellular response to metal ion GO:0071248 55 0.010
negative regulation of response to external stimulus GO:0032102 37 0.010
cellular macromolecule localization GO:0070727 122 0.010
Yeast
regulation of blood circulation GO:1903522 110 0.010
protein complex biogenesis GO:0070271 263 0.010
cellular response to oxidative stress GO:0034599 76 0.010
regulation of sensory perception GO:0051931 29 0.010
cellular response to inorganic substance GO:0071241 65 0.010
membrane depolarization during action potential GO:0086010 1 0.010
positive regulation of signal transduction GO:0009967 175 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
gonad development GO:0008406 104 0.010
feeding behavior GO:0007631 53 0.010
regulation of transferase activity GO:0051338 123 0.010
regulation of protein kinase activity GO:0045859 105 0.010
neurotrophin signaling pathway GO:0038179 18 0.010
regulation of synaptic transmission glutamatergic GO:0051966 26 0.010

Sorcs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.036
disease of anatomical entity DOID:7 0 0.036
central nervous system disease DOID:331 0 0.017
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011